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Hip Pathology

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https://www.readbyqxmd.com/read/28546767/increase-and-regulation-of-synovial-calcitonin-gene-related-peptide-expression-in-patients-with-painful-knee-osteoarthritis
#1
Shotaro Takano, Kentaro Uchida, Gen Inoue, Atsushi Minatani, Masayuki Miyagi, Jun Aikawa, Dai Iwase, Kenji Onuma, Manabu Mukai, Masashi Takaso
BACKGROUND: Recent studies suggest that the vasodilatory neuropeptide calcitonin gene-related peptide (CGRP) is localized in the synovial tissue and may be involved in the pathology of hip and knee osteoarthritis (OA). However, the regulation and relationship between pain and CGRP expression levels in the synovial tissue of human OA patients are not fully understood. METHODS: Synovial tissues were harvested from 74 participants with radiographic knee OA (unilateral Kellgren/Lawrence grades 3-4) during total knee arthroplasty...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28539168/effectiveness-of-nutritional-supplementation-on-sarcopenia-and-recovery-in-hip-fracture-patients-a-multi-centre-randomized-trial
#2
Vincenzo Malafarina, Francisco Uriz-Otano, Concetta Malafarina, J Alfredo Martinez, M Angeles Zulet
BACKGROUND AND OBJECTIVES: Functional deterioration and reduced mobility in elderly patients with a hip fracture are associated with a loss of both muscle mass and function (sarcopenia). The aim of this study was to assess whether oral nutritional supplementation (ONS) improves muscle mass and nutritional markers (BMI, proteins) in elderly patients with hip fracture. METHODS: Patients aged 65 years and over with hip fractures admitted to either of two rehabilitation facilities were included...
July 2017: Maturitas
https://www.readbyqxmd.com/read/28537994/changes-in-gait-parameters-after-femoral-derotational-osteotomy-in-cerebral-palsy-patients-with-medial-femoral-torsion
#3
Ha Yong Kim, Yong Han Cha, Jae Yong Byun, Young Sub Chun, Won Sik Choy
Medial femoral torsion (MFT) is a common pathologic gait in cerebral palsy (CP) children that can be corrected by femoral derotational osteotomy (FDO). It is not clearly known as to how much various gait parameters change after FDO. The aim of this study was to quantify changes in gait parameters after FDO. The study group included 19 young CP patients (28 limbs, age<20 years, average age: 13.2 years) with symptomatic MFT, treated with distal FDO. The study group was divided into two groups: the unilateral FDO group (UG) and the bilateral FDO group (BG)...
May 19, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28537235/-serotonergic-genes-in-the-development-of-anxiety-depression-like-state-and-pathology-of-aggressive-behavior-in-male-mice-rna-seq-data
#4
N N Kudryavtseva, D A Smagin, I L Kovalenko, A G Galyamina, G B Vishnivetskaya, V N Babenko, Yu L Orlov
In course of daily agonistic interactions, mice tend to stratify into those with chronic social defeats and those that repeatedly display aggression, which lead to the development of mixed anxiety/depression-like state and the pathology of aggressive behavior, respectively. Using the data of whole transcriptome analysis (RNA-seq), the changes in the expression of serotonergic genes involved in the synthesis, inactivation, and reception of serotonin, as well as of the Creb1 (transcription factor) gene and the Bdnf (brain-derived neurotrophic factor) gene were detected in the striatum (STR), ventral tegmental area (VTA), midbrain raphe nuclei (MRN), hypothalamus (HYP), and hippocampus (HIP) of defeated and aggressive male mice...
March 2017: Molekuliarnaia Biologiia
https://www.readbyqxmd.com/read/28536211/pathological-fracture-of-the-femoral-neck-following-septic-coxitis-and-chronic-osteomyelitis-a-potential-complication-of-lemierre-s-syndrome
#5
Dominik Maximilian Vogt, Ludger Tüshaus, Martin Kaiser, Martin Russlies
We portray the case of a 16-year-old girl who was initially admitted to the paediatric emergency department with non-specific symptoms of a severe cold and was first treated symptomatically on an ambulatory basis. Within 6 days she developed the full clinical picture of Lemierre's syndrome with the extraordinary manifestation of involvement of her right hip. Despite an interdisciplinary coordinated treatment as well as surgical therapy, a full-blown sepsis evolved within a short time period and resulted in almost 2 months of intensive care...
May 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28532220/the-adipokine-tartrate-resistant-acid-phosphatase-5a-in-serum-correlates-to-adipose-tissue-expansion-in-obesity
#6
Christina Patlaka, Laia Mira Pascual, Staffan Paulie, Anni-Frid Henriksson, Peter Arner, Pernilla Lång, Göran Andersson
PURPOSE: Tartrate resistant acid phosphatase (TRAP) exists as two isoforms, 5a and 5b. TRAP 5a is elevated in adipose tissue of obese women, interacts with pre-adipocytes and is linked to insulin-sensitive hyperplastic obesity when overexpressed in mice. The aim of this study was to investigate the relation between serum TRAP 5a, adiposity indices and metabolic syndrome risk markers in lean and obese women, using a newly developed TRAP 5a-specific ELISA. MATERIALS AND METHODS: A TRAP 5a sandwich ELISA was optimized using TRAP 5a-specific monoclonal antibodies and tested in sera of healthy males...
May 22, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/28516234/assessing-long-term-return-to-play-after-hip-arthroscopy-in-football-players-evaluating-risk-factors-for-good-prognosis
#7
D Barastegui, R Seijas, P Alvarez-Diaz, E Rivera, E Alentorn-Geli, G Steinbacher, X Cuscó, R Cugat
PURPOSE: Groin pain is the third most common disease in football players and has often been associated with hip pathology such as femoroacetabular impingement and labral lesions. Hip arthroscopy offers possibilities of function restoration via minimally invasive procedures. The aim of this study is to evaluate professional football player's injuries and their return to play after hip arthroscopy for FAI and labral injuries. METHODS: Patients that underwent hip arthroscopy between 2009 and 2014 were selected retrospectively...
May 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28509827/leptin-elevation-as-a-risk-factor-for-slipped-capital-femoral-epiphysis-independent-of-obesity-status
#8
Schuyler J Halverson, Tracy Warhoover, Gregory A Mencio, Steven A Lovejoy, Jeffrey E Martus, Jonathan G Schoenecker
BACKGROUND: Slipped capital femoral epiphysis (SCFE) is strongly associated with childhood obesity, yet the prevalence of obesity is orders of magnitude greater than the prevalence of SCFE. Therefore, it is hypothesized that obesity is not, by itself, a sufficient condition for SCFE, but rather one component of a multifactorial process requiring preexisting physeal pathology. Leptin elevation is seen to varying degrees in patients with obesity, and as leptin has been shown to cause physeal pathology similar to the changes seen in SCFE, we propose that leptin may be a factor distinguishing between patients with SCFE and equally obese children without hip abnormalities...
May 17, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28509596/joint-moment-angle-properties-of-the-hip-abductors-and-hip-extensors
#9
Curtis Kindel, John Challis
PURPOSE: Strengthening of hip joint musculature is common in the rehabilitation of the lower extremity. However, strength curves for hip abduction and extension have not been assessed when varying the position of the knee. The force-length properties of the biarticular muscles can be affected when altering the position of the knee during the production of hip moments. METHODS: Maximum isometric joint moments were measured at four different angles of hip abduction and hip extension, at the two knee positions (0° and 90°)...
May 16, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28507970/a-new-technique-for-surgical-treatment-of-proximal-hamstring-tendinopathy-in-a-triathlon-athlete
#10
Lincoln Paiva Costa, Antônio Augusto Guimarães Barros, Carlos Cesar Vassalo, Bertrand Sonnery-Cottet, Victor Atsushi Kasuya Barbosa, Eduardo Frois Temponi
INTRODUCTION: Proximal hamstring tendinopathy (PHT) is the result of chronic overload caused by repetitive eccentric contraction. Surgical treatment becomes an option for patients with chronic symptoms that do not respond to conservative treatment. CASE REPORT: This report describes a case of a 48-year-old man, an amateur triathlete, with deep gluteal pain in the left hip for 12 months, leading to a decline in sports performance. Magnetic resonance imaging revealed abnormalities that suggested a PHT...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28507967/surgery-of-a-rare-case-of-multiple-synovial-osteochondromatosis-of-the-hip-joint
#11
Yi Min Zhang, Xiaoguang Liu
INTRODUCTION: Primary synovial osteochondromatosis of the hip is a benign disorder, which is not frequently seen clinically. The characteristic of this disease is proliferation of synovium and formation of loose bodies inside the joint. It is known that only the loose bodies derived from synovium were called synovial osteochondromatosis. Although it can take place in any joint, the knee is most commonly affected, involvement of the hip joint is relatively rare. We report a young man who has multiple synovial osteochondromatosis in his left hip...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28507776/the-current-situation-in-hip-arthroscopy
#12
REVIEW
Oliver Marin-Peña, Marc Tey-Pons, Luis Perez-Carro, Hatem G Said, Pablo Sierra, Pedro Dantas, Richard N Villar
Hip arthroscopy is an evolving surgical technique that has recently increased in popularity.Although femoroacetabular impingement was an important launch pad for this technique, extra-articular pathology has been described through hip endoscopy.Good clinical results in the medium term will allow improvements in this technique and increase its indications. Cite this article: EFORT Open Rev 2017;2:58-65. DOI: 10.1302/2058-5241.2.150041.
March 2017: EFORT Open Rev
https://www.readbyqxmd.com/read/28506617/arthroscopic-treatment-of-hip-pain-in-adolescent-patients-with-borderline-dysplasia-of-the-hip-minimum-2-year-follow-up
#13
Peter T Evans, John M Redmond, Jon E Hammarstedt, Yuan Liu, Edwin O Chaharbakhshi, Benjamin G Domb
PURPOSE: To examine arthroscopic treatment of hip pain in patients with borderline hip dysplasia (lateral center edge angle [LCEA] between 20° and 25°). METHODS: From 2008 to 2013, patients below 18 years of age who underwent arthroscopic hip surgery with an LCEA between 20° and 25° were retrospectively matched 1:1 to a control group without dysplasia (LCEA ≥25°) based on age, gender, femoroplasty, labral treatment, and capsular plication. Indications for surgery included failure to improve with nonoperative treatments and anti-inflammatory medications after 3 months...
May 12, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28506616/outcomes-of-hip-arthroscopy-in-competitive-athletes
#14
Itay Perets, David E Hartigan, Edwin O Chaharbakhshi, Lyall Ashberg, Victor Ortiz-Declet, Benjamin G Domb
PURPOSE: To evaluate the minimum 2-year postoperative clinical outcomes and the rate of return to sports in athletes who underwent capsular plication for the treatment of ligamentous laxity and/or borderline dysplasia during hip arthroscopy for the treatment of femoroacetabular impingement and labral pathology. METHODS: Since 2008, data were prospectively collected on patients who underwent hip arthroscopy for the treatment of femoroacetabular impingement and/or labral tears...
May 12, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28501221/return-to-sport-and-clinical-outcomes-after-hip-arthroscopic-labral-repair-in-young-amateur-athletes-minimum-2-year-follow-up
#15
Rohith Mohan, Nick R Johnson, Mario Hevesi, Christopher M Gibbs, Bruce A Levy, Aaron J Krych
PURPOSE: To determine the rate of return of young amateur athletes to sport after hip arthroscopy, their clinical outcomes, and pathologic risk factors for worse outcomes 2 years after surgery. METHODS: This study included all patients between age 13 and 23 who participated in a sport prior to surgery with intent to return who underwent hip arthroscopy after failure of comprehensive nonoperative management for whom 2-year outcome scores were available. Outcomes collected retrospectively included modified Harris Hip Score (mHHS) and the Hip Outcome Scores (HOS) subscales for activities of daily living (ADL) and sport (HOS Sport)...
May 10, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28487630/analysis-of-interrelationships-among-voluntary-and-prosthetic-leg-joint-parameters-using-cyclograms
#16
Farahiyah Jasni, Nur Azah Hamzaid, Nor Elleeiana Mohd Syah, Tze Y Chung, Noor Azuan Abu Osman
The walking mechanism of a prosthetic leg user is a tightly coordinated movement of several joints and limb segments. The interaction among the voluntary and mechanical joints and segments requires particular biomechanical insight. This study aims to analyze the inter-relationship between amputees' voluntary and mechanical coupled leg joints variables using cyclograms. From this analysis, the critical gait parameters in each gait phase were determined and analyzed if they contribute to a better powered prosthetic knee control design...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28484993/hip-fracture-pattern-at-a-major-tanzanian-referral-hospital-focus-on-fragility-hip-fractures
#17
Munyaradzi Tsabasvi, Sonya Davey, Rogers Temu
This study examined hip fractures during a 5-year period at Kilimanjaro Christian Medical Center (KCMC). There was a general increase in proportions of fragility hip fractures during this period. PURPOSE: Fragility hip fractures are expected to increase in low-resource countries. This study examined hip fractures in the osteoporotic age group during a 5-year period at the Kilimanjaro Christian Medical Center (KCMC), which is located in Moshi, Tanzania. METHODS: We conducted a retrospective study of all hip fracture patients above the age of 50 who were admitted to KCMC between January 1, 2011 and December 31, 2015...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28479436/a-synovial-cyst-originating-from-the-hip-joint-as-a-rare-cause-of-recurrent-femoral-vein-thrombosis-case-report-and-literature-review
#18
Michael Keese, Firouza Dahi, Edelgard Lindhoff-Last
Thrombosis of the femoral vein may be caused by external obstruction. A 48-year-old female patient presented with leg swelling and a history of recurrent femoral venous thrombosis caused by a ganglion originating from the left hip joint. A CT-guided puncture had also been performed, which was followed by rapid refilling of the cyst. Thereafter, femoral vein was decompressed and the ganglion was resected. Pathology confirmed a synovial cyst. After an uneventful stay the patient was discharged on oral anticoagulation...
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28474251/hip-fractures-in-young-adults-a-retrospective-cross-sectional-study-of-characteristics-injury-mechanism-risk-factors-complications-and-follow-up
#19
Michael T Wang, Sarah H Yao, Phillip Wong, Anne Trinh, Peter R Ebeling, Ton Tran, Frances Milat, Nora Mutalima
This study characterises risk factors, complications and follow-up of minimal trauma hip fractures in young adults, adding to limited information examining the management framework. This group have severe systemic disease and significant risk of post-operative complications and subsequent fractures. Improved medical referral pathways enable management of osteoporosis and comorbid diseases. AIMS: There is a paucity of literature examining minimal trauma hip fractures in young adults, despite extensive management guidelines for older patients...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28473519/feasibility-of-administrative-data-for-studying-complications-after-hip-fracture-surgery
#20
Katie Jane Sheehan, Boris Sobolev, Pierre Guy, Michael Tang, Lisa Kuramoto, Philip Belmont, James A Blair, Susan Sirett, Suzanne N Morin, Donald Griesdale, Susan Jaglal, Eric Bohm, Jason M Sutherland, Lauren Beaupre
PURPOSE: There is limited information in administrative databases on the occurrence of serious but treatable complications after hip fracture surgery. This study sought to determine the feasibility of identifying the occurrence of serious but treatable complications after hip fracture surgery from discharge abstracts by applying the Agency for Healthcare Research and Quality (AHRQ) Patient Safety Indicator 4 (PSI-4) case-finding tool. METHODS: We obtained Canadian Institute for Health Information discharge abstracts for patients 65 years or older, who were surgically treated for non-pathological first hip fracture between 1 January 2004 and 31 December 2012 in Canada, except for Quebec...
May 4, 2017: BMJ Open
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