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https://www.readbyqxmd.com/read/29130113/long-term-results-of-closed-reduction-for-developmental-dislocation-of-the-hip-in-children-of-walking-age-under-eighteen-months-old
#1
Soo Min Cha, Hyun Dae Shin, Byung Kon Shin
BACKGROUND: Developmental dysplasia of the hip (DDH) diagnosed in older postnatal children can be effectively treated by closed reduction (CR) alone. However, no prospective or comparative trial to explore the differential effectiveness of CR between non-walking and walking postnatal children has yet been reported. This study investigated the clinical and radiologic outcomes of CR in the age range of interest (12-18 months old) via a prospective trial and compared these results with those of a younger age group who also underwent CR...
November 13, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29125919/autologous-chondrocyte-implantation-sandwich-technique-compared-with-autologous-bone-grafting-for-deep-osteochondral-lesions-in-the-knee
#2
Tom Minas, Takahiro Ogura, Jeff Headrick, Tim Bryant
BACKGROUND: Treating symptomatic osteochondral defects is challenging, especially in young adults with deep (>8-10 mm) empty defects after osteochondritis dissecans (OCD) or collapsed condyles secondary to avascular necrosis (AVN). For this population, osteoarthritis (OA) is inevitable if articular congruence is not restored. PURPOSE: To describe the autologous chondrocyte implantation (ACI) "sandwich" technique with autologous bone grafting (ABG) and compare it with ABG alone for restoration of the osteochondral unit...
November 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29114187/use-of-fibular-bone-graft-and-cancellous-screw-fixation-in-the-management-of-neglected-femur-neck-fractures-in-young-patients
#3
Ghulam Mustafa Kaim Khani, Kamran Hafeez, Muhammad Bux, Nusrat Rasheed, Naveed Ahmed, M Perwez Anjum
Objective: To present the clinical outcome of patients with neglected femur neck fracture treated with fibular bone graft. Methods: During May 2010-February 2013, 15 patients younger than 35 years of age with neglected fracture neck of femur were managed with non-vascularized fibular graft and cannulated screws. Fractures were classified according to Sandhu Classification. Hip function was assessed using Harris hip score. Results: Fifteen patients with mean age of 28...
November 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/29106948/good-functional-outcome-but-not-regained-health-related-quality-of-life-in-the-majority-of-20-69-years-old-patients-with-femoral-neck-fracture-treated-with-internal-fixation-a-prospective-2-year-follow-up-study-of-182-patients
#4
Pierre Campenfeldt, Margareta Hedström, Wilhelmina Ekström, Amer N Al-Ani
BACKGROUND AND PURPOSE: Prospective studies on patient related outcome in patients <70years with a femoral neck fracture (FNF) are few. We aimed to investigate functional outcome and health-related quality of life (HRQoL) in 20-69years old patients with a FNF treated with internal fixation. PATIENTS AND METHODS: 182 patients, 20-69years with a FNF treated with internal fixation were prospectively included in a multicenter study. Follow up included radiographic and clinical examination at 4, 12 and 24 months...
October 18, 2017: Injury
https://www.readbyqxmd.com/read/29081846/avascular-necrosis-in-children-with-cerebral-palsy-after-reconstructive-hip-surgery
#5
L Phillips, K Hesketh, E K Schaeffer, J Andrade, J Farr, K Mulpuri
PURPOSE: Progressive hip displacement is one of the most common orthopaedic pathologies in children with cerebral palsy (CP). Reconstructive hip surgery has become the standard treatment of care. Reported avascular necrosis (AVN) rates for hip reconstructive surgery in these patients vary widely in the literature. The purpose of this study is to identify the frequency and associated risk factors of AVN for reconstructive hip procedures. METHODS: A retrospective analysis was performed of 70 cases of reconstructive hip surgery in 47 children with CP, between 2009 and 2013...
October 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29075150/avenanthramide-c-reduces-the-viability-of-mda-mb-231-breast-cancer-cells-through-an-apoptotic-mechanism
#6
Jordan Hastings, Jason Kenealey
BACKGROUND: Avenanthramides (AVN) are a relatively unstudied family of phytochemicals that could be novel chemotherapeutics. These compounds, found in oats, are non-toxic to healthy cells and have been shown to reduce viability of human colon and liver cancers in vitro. However, these studies do not elucidate a molecular mechanism for individual AVN. In this study we aim to see the effects of AVN on MDA-MB-231 breast cancer cells. METHODS: An MTT assay was used to determine cell viability...
2017: Cancer Cell International
https://www.readbyqxmd.com/read/29068514/high-incidence-of-aseptic-hip-necrosis-in-hodgkin-lymphoma-patients-treated-with-escalated-beacopp-receiving-methylprednisolone
#7
Sandra Basic-Kinda, Ivan Karlak, Nadira Durakovic, Zvonimir Ivan Lubina, Ivo Radman, Snježana Dotlic, Zinaida Peric, Ida Hude, Igor Aurer
BACKGROUND: Escalated BEACOPP (eBEACOPP) is an effective but fairly toxic regimen for treatment of Hodgkin lymphoma (HL). Avascular necrosis of femoral head (AVN) was previously reported to be increased in patients treated with eBEACOPP, but so far no systematic analysis of its frequency has been published. AIMS: We aimed to analyze frequency and identify possible risk factors for AVN development in patients treated with eBEACOPP. METHODS: We identified 26 patients treated with eBEACOPP for newly diagnosed high-risk advanced stage HL, 25 patients alive at the time of study...
October 25, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29068288/timing-of-surgical-intervention-for-developmental-dysplasia-of-the-hip-a-randomised-controlled-trial-hip-op
#8
Charlotte L Williams, Susie Weller, Lisa Roberts, Isabel Reading, Andrew Cook, Louisa Little, Wendy Wood, Louise Stanton, Andreas Roposch, Nicholas Mp Clarke
BACKGROUND: Developmental dysplasia of the hip (DDH) is a very common congenital disorder, and late-presenting cases often require surgical treatment. Surgical reduction of the hip may be complicated by avascular necrosis (AVN), which occurs as a result of interruption to the femoral head blood supply during treatment and can result in long-term problems. Some surgeons delay surgical treatment until the ossific nucleus (ON) has developed, whereas others believe that the earlier the reduction is performed, the better the result...
October 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29061495/femoral-osteochondroplasty-can-be-performed-effectively-without-the-risk-of-avascular-necrosis-or-femoral-neck-fractures-in-an-experimental-ovine-fai-model
#9
F Schmaranzer, L Arendt, T D Lerch, S D Steppacher, K Nuss, N Wolfer, H E Dawson, B von Rechenberg, P R Kircher, M Tannast
OBJECTIVE: The experimental induction of cam-type femoroacetabular impingement (FAI) in sheep is established. To tap the full potential of this ovine model, one should be able to perform a femoral osteochondroplasty safely. This study was based on previous cadaver experiments on the blood supply to the ovine femoral head and on the biomechanical strength of the proximal femur following offset creation. We hypothesized that offset creation in this ovine FAI model does not lead to (1) avascular necrosis (AVN) of the ovine femoral head or (2) iatrogenic femoral neck fractures and (3) can be performed effectively...
October 20, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29027184/low-rate-of-clinically-important-avascular-necrosis-of-the-femoral-head-after-ludloff-s-procedure
#10
Jesper Holbeck-Brendel, Bjarne Møller-Madsen, Ivan Hvid, Michel B Hellfritzsch, Line K Pedersen, Peter Dalsgaard, Ole Rahbek
INTRODUCTION: Ludloff's procedure for open reduction of congenital dislocation of the hip (CDH) is recommended for its minimal tissue damage, but is criticised for the risk of late avascular necrosis (AVN) of the femoral head. The aim of present study was primarily to assess the risk of late AVN of the femoral head and secondly the range of motion (ROM) of the hip and the quality of life in children following Ludloff's procedure. METHODS AND MATERIALS: 13 hips in 11 children after Ludloff's procedure due to CDH were included retrospectively from 1997 to 2005 at Aarhus University Hospital...
October 12, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29026869/associations-between-antiretroviral-treatment-and-avascular-bone-necrosis-the-swiss-hiv-cohort-study
#11
Cornelia Bayard, Bruno Ledergerber, Markus Flepp, Thanh Lecompte, Estelle Moulin, Matthias Hoffmann, Rainer Weber, Cornelia Staehelin, Caroline Di Benedetto, Christoph A Fux, Philip E Tarr, Barbara Hasse
BACKGROUND: HIV-infected individuals have an increased risk of avascular bone necrosis (AVN). Antiretroviral therapy (ART) and particularly protease inhibitors (PI) have been implicated as a risk factor. We aimed to study the associations of ART with the occurrence of AVN among Swiss HIV Cohort Study participants (SHCS). METHODS: We used incidence density sampling to perform a case control study within the Swiss HIV Cohort Study (SHCS) comparing prospectively collected AVN cases and controls by conditional logistic regression analysis...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28975397/traumatic-inferior-shoulder-dislocation-a-review-of-management-and-outcome
#12
REVIEW
M Nambiar, D Owen, P Moore, A Carr, M Thomas
INTRODUCTION: Traumatic inferior shoulder dislocation (ISD) is rare, estimated to occur in 0.5% of all shoulder dislocations. We describe the demographics, natural history and outcome of this injury. HYPOTHESIS/AIM: The aim of the study is to provide a summary of the demographics, clinical presentation, management and outcome of patients who suffer ISD METHODS: We conducted a systematic review of the English language literature on ISD using PubMed, Medline, CINHAL, Cochrane Database and Evidence-Based Medicine Reviews...
October 3, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28971937/a-complete-characterization-of-all-versus-nothing-arguments-for-stabilizer-states
#13
Samson Abramsky, Rui Soares Barbosa, Giovanni Carù, Simon Perdrix
An important class of contextuality arguments in quantum foundations are the all-versus-nothing (AvN) proofs, generalizing a construction originally due to Mermin. We present a general formulation of AvN arguments and a complete characterization of all such arguments that arise from stabilizer states. We show that every AvN argument for an n-qubit stabilizer state can be reduced to an AvN proof for a three-qubit state that is local Clifford-equivalent to the tripartite Greenberger-Horne-Zeilinger state. This is achieved through a combinatorial characterization of AvN arguments, the AvN triple theorem, whose proof makes use of the theory of graph states...
November 13, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28963163/cemented-total-hip-arthroplasty-following-acetabular-fracture
#14
C E H Scott, D MacDonald, M Moran, T O White, J T Patton, J F Keating
AIMS: To evaluate the outcomes of cemented total hip arthroplasty (THA) following a fracture of the acetabulum, with evaluation of risk factors and comparison with a patient group with no history of fracture. PATIENTS AND METHODS: Between 1992 and 2016, 49 patients (33 male) with mean age of 57 years (25 to 87) underwent cemented THA at a mean of 6.5 years (0.1 to 25) following acetabular fracture. A total of 38 had undergone surgical fixation and 11 had been treated non-operatively; 13 patients died at a mean of 10...
October 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28951638/non-parallel-screw-fixation-for-femoral-neck-fractures-in-young-adults
#15
Sherif Galal, Mohamed Nagy
INTRODUCTION: Current literature shows divergence of views regarding screws positioning in femoral neck fractures fixation. The goal of this study is to evaluate the efficiency of divergent screw fixation for fracture neck of femur (NOF). METHODS: The study was conducted at an academic Level 1 Trauma Center. This is a retrospective study conducted from October 2013 to October 2016. The study included 41 patients (33 males, 8 females) suffering from fracture NOF who were fixed using BDSF technique (26 within 24 h...
July 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28904634/treatment-of-chronic-stable-slipped-capital-femoral-epiphysis-via-surgical-hip-dislocation-with-combined-osteochondroplasty-and-imhauser-osteotomy
#16
J B Erickson, W P Samora, K E Klingele
PURPOSE: Treatment of slipped capital femoral epiphysis (SCFE), including the modified Dunn procedure, restores anatomy with significant risk for avascular necrosis (AVN), if performed in the setting of moderate to severe, stable SCFE. The Imhauser osteotomy has been shown to be an effective way to correct residual deformity without the risk of AVN. We sought to evaluate the effectiveness and safety of a combined Imhauser osteotomy and osteochondroplasty, performed via a surgical hip dislocation approach for the acute and delayed treatment of stable SCFE...
August 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28893630/engineered-axially-vascularized-osteogenic-grafts-from-human-adipose-derived-cells-to-treat-avascular-necrosis-of-bone-in-a-rat-model
#17
Tarek Ismail, Rik Osinga, Atanas Todorov, Alexander Haumer, Laurent A Tchang, Christian Epple, Nima Allafi, Nadia Menzi, René D Largo, Alexandre Kaempfen, Ivan Martin, Dirk J Schaefer, Arnaud Scherberich
BACKGROUND: Avascular necrosis of bone (AVN) leads to sclerosis and collapse of bone and joints. The standard of care, vascularized bone grafts, is limited by donor site morbidity and restricted availability. The aim of this study was to generate and test engineered, axially vascularized SVF cells-based bone substitutes in a rat model of AVN. METHODS: SVF cells were isolated from lipoaspirates and cultured onto porous hydroxyapatite scaffolds within a perfusion-based bioreactor system for 5days...
November 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28874289/clinical-predictors-of-challenging-atrioventricular-node-ablation-procedure-for-rate-control-in-patients-with-atrial-fibrillation
#18
Baptiste Polin, Nathalie Behar, Vincent Galand, Vincent Auffret, Albin Behaghel, Dominique Pavin, Jean-Claude Daubert, Philippe Mabo, Christophe Leclercq, Raphael P Martins
INTRODUCTION: Atrioventricular node (AVN) ablation is usually a simple procedure but may sometimes be challenging. We aimed at identifying pre-procedural clinical predictors of challenging AVN ablation. METHODS: Patients referred for AVN ablation from 2009 to 2015 were retrospectively included. Baseline clinical data, procedural variables and outcomes of AVN ablation were collected. A "challenging procedure" was defined 1) total radiofrequency delivery to get persistent AVN block≥400s, 2) need for left-sided arterial approach or 3) failure to obtain AVN ablation...
October 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28865592/corrigendum-to-case-series-of-17-modified-weil-s-osteotomies-for-freiberg-s-and-k%C3%A3-hler-s-ii-avn-with-aofas-scoring-pre-and-post-operatively-foot-ankle-surg-17-1-2011-19-24
#19
M C Edmondson, K R Sherry, J Afolayan, A R Armitage, A D Skyrme
No abstract text is available yet for this article.
September 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28861192/comparison-of-outcomes-of-total-hip-arthroplasty-between-patients-with-ankylosing-spondylitis-and-avascular-necrosis-of-the-femoral-head
#20
Sun-Ho Lee, Gun-Woo Lee, Young-Jun Seol, Kyung-Soon Park, Taek-Rim Yoon
BACKGROUND: The objective of this study was to compare clinical and radiological outcomes of total hip arthroplasty (THA) between ankylosing spondylitis (AS) of the hip joint and avascular necrosis (AVN) of the femoral head. METHODS: Thirty patients (30 hips) underwent cementless THA for AS between 2003 and 2012. They were compared to 30 patients (30 hips) who underwent the same procedure for AVN of the femoral head. Each group was matched for age and gender, and both groups had similar preoperative demographic characteristics...
September 2017: Clinics in Orthopedic Surgery
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