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https://www.readbyqxmd.com/read/29775801/narrative-review-on-the-effect-of-shockwave-treatment-for-management-of-upper-and-lower-extremity-musculoskeletal-conditions
#1
REVIEW
Julia M Reilly, Eric Bluman, Adam S Tenforde
Extracorporeal shockwave therapy (ESWT) is a technology that was first introduced into clinical practice in 1982 for urological conditions. Subsequent clinical applications in musculoskeletal conditions have been described in treatment of plantar fasciopathy, both upper and lower extremity tendinopathies, greater trochanteric pain syndrome, medial tibial stress syndrome, management of non-union fractures, and joint disease including avascular necrosis (AVN). The aim of this review is to summarize the current understanding of treatment of musculoskeletal conditions with ESWT, accounting for differences in treatment protocol and energy levels...
May 15, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29752504/duration-of-immobilization-after-developmental-dysplasia-of-the-hip-and-open-reduction-surgery
#2
Khaled Emara, Mohamed Ahmed Al Kersh, Fahad Abdulazeez Hayyawi
BACKGROUND: There is no consensus about the duration of post-operative immobilization in the treatment of DDH (developmental dysplasia of hip). Our aim in this study is to compare between two post-operative immobilization protocols for patients undergoing open reduction. MATERIALS AND METHODS: Thirty-eight hips in 32 patients assigned to group A were immobilized in hip spica for four weeks followed by abduction brace application which was gradually weaned through the periods of several months and 29 hips in 24 patients assigned to group B immobilized in hip spica for 12 weeks without further bracing...
May 11, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29726862/natural-and-synthetic-avenanthramides-activate-caspases-2-8-3-and-downregulate-htert-mdr1-and-cox-2-genes-in-caco-2-and-hep3b-cancer-cells
#3
E S Scarpa, M Mari, E Antonini, F Palma, P Ninfali
Avenanthramides (AVNs) are natural polyphenols obtained from oat sprouts and can also be chemically synthetized. The aim of the present study was to assess the anticancer, anti-inflammatory and antioxidant effects of individual synthetized AVNs (s-2c, s-2p, s-2f) and a natural AVN mixture (n-MIX) on CaCo-2 and Hep3B cancer cells. In CaCo-2, the AVN s-2c was found to be the most cytotoxic followed by the n-MIX. In Hep3B cells, a marked cytotoxic effect was found but no significant difference was observed between the synthesized AVNs and the n-MIX...
May 4, 2018: Food & Function
https://www.readbyqxmd.com/read/29715363/hip-joint-contact-pressure-distribution-during-pavlik-harness-treatment-of-an-infant-hip-a-patient-specific-finite-element-model
#4
Behzad Vafaeian, Samer Adeeb, Marwan El-Rich, Dornoosh Zonoobi, Abhilash R Hareendranathan, Jacob L Jaremko
Developmental dysplasia of the hip (DDH) in infants under 6 months of age is typically treated by the Pavlik harness (PH). During successful PH treatment, a subluxed/dislocated hip is spontaneously reduced into the acetabulum, and DDH undergoes self-correction. PH treatment may fail due to avascular necrosis (AVN) of the femoral head. An improved understanding of mechanical factors accounting for the success/failure of PH treatment may arise from investigating articular cartilage contact pressure (CCP) within a hip during treatment...
July 1, 2018: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29687316/bernese-type-triple-pelvic-osteotomy-through-a-single-incision-in-children-over-five-years-a-retrospective-study-of-twenty-eight-cases
#5
YiQiang Li, HongWen Xu, Theddy Slongo, QingHe Zhou, Yuanzhong Liu, WeiDong Chen, JingChun Li, Federico Canavese
INTRODUCTION: Bernese-type triple pelvic osteotomy (BTPO) combines periacetabular and triple innominate osteotomy techniques. However, studies that evaluate the clinical and radiographic outcomes of BTPO are scarce. The aim of this study is to report on the clinical and radiographic outcomes of ambulatory children with developmental dysplasia of the hip (DDH) or Legg-Calvé-Perthes disease (LCPD) managed with BTPO that were older than five years of age at the time of surgery. MATERIALS AND METHODS: We retrospectively reviewed the records of 27 consecutive patients with DDH or LCPD (mean age 7...
April 23, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29681819/avascular-necrosis-of-bone-following-chemotherapy-in-cancer-patients-with-coagulopathy-report-of-two-cases
#6
Hui-Ching Hsu, Tzu-Yao Liao, Dave Wei-Chih Chen, Yu-Hsiang Juan, Chuang-Chi Liaw
We report 2 cases of patients with solid tumors and coagulopathy who experienced avascular necrosis (AVN) of the bone following chemotherapy. Both cases exhibited nontraumatic bilateral AVN of the femoral heads, and one also showed bilateral AVN of the humeral heads. One case had multiple thromboembolic complications, including pulmonary obstructive syndrome and paraneoplastic pain. The other showed multiple paraneoplastic syndromes, with hypercalcemia and thrombocytosis. Groin pain and claudication of the lower extremities developed and persisted...
January 2018: Case Reports in Oncology
https://www.readbyqxmd.com/read/29624126/health-related-quality-of-life-and-personal-life-goals-of-adults-with-sickle-cell-disease-after-hematopoietic-stem-cell-transplantation
#7
Agatha M Gallo, Crystal Patil, Tokunbo Adeniyi, Lewis L Hsu, Damiano Rondelli, Santosh Saraf
Allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen (HLA)-matched sibling donor offers a unique therapy to reverse SCD. This mixed-methods study explores recipients' perception of HSCT success, personal life goals, and associated health-related quality of life (HRQOL) more than 1 year after HSCT. Recipients completed the Short Form-36, version 1 (SF-36v1) HRQOL survey followed by a 60- to 90-min face-to-face or telephone audio-recorded interview. Eleven of 15 eligible recipients participated in the study...
April 1, 2018: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/29623481/effect-of-antazoline-on-electrophysiological-properties-of-atrial-muscle-and-conduction-system-of-the-heart
#8
Bartłomiej Jacek Bińkowski, Marcin Makowski, Paweł Kubiński, Andrzej Lubiński
PURPOSE: Antazoline is a first-generation antihistaminic agent with additional anticholinergic properties and antiarrhythmic potential. Recent data shows its high effectiveness in sinus rhythm restoration among patients with paroxysmal atrial fibrillation. The effect of antazoline on electrophysiological parameters of the heart in vivo has not yet been examined. The aim of this study was to evaluate changes in electrophysiological parameters of the heart muscle and conduction system as a response to increasing doses of antazoline...
April 6, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29619587/rheumatic-diseases-in-hiv-infected-patients-in-the-post-antiretroviral-therapy-era-a-tertiary-care-center-experience
#9
Konstantinos Parperis, Yasir Abdulqader, Robert Myers, Bikash Bhattarai, Muhsen Al-Ani
The aim of the study was to calculate the proportion of rheumatic diseases in HIV patients who were receiving ART and to identify association of the HIV medications with the development of rheumatologic diseases. We conducted a retrospective chart review during the period of 2010 to 2016. We identified 2996 patients as having chronic HIV infection and on ART, and we collected data regarding patient's demographic characteristics, comorbidities, CD 4 count, HIV viral load, and ART. One hundred thirteen out of 2996 HIV patients (3...
April 4, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29580297/clinical-impact-of-pure-empirical-catheter-ablation-of-slow-pathway-in-patients-with-non-ecg-documented-clinical-on-off-tachycardia
#10
Shqipe Gerguri, Nikesh Jathanna, Tina Lin, Patrick Müller, Lukas Clasen, Jan Schmidt, Muhammed Kurt, Dong-In Shin, Christian Blockhaus, Malte Kelm, Alexander Fürnkranz, Hisaki Makimoto
BACKGROUND: Catheter ablation of slow-pathway (CaSP) has been reported to be effective in patients with dual atrioventricular nodal conduction properties (dcp-AVN) and clinical ECG documentation but without the induction of tachycardia during electrophysiological studies (EPS). However, it is unknown whether CaSP is beneficial in the absence of pre-procedural ECG documentation and without the induction of tachycardia during EPS. The aim of this study was to evaluate long-term results after a "pure" empirical CaSP (peCaSP)...
March 27, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29570157/femoral-head-wedge-resection-for-the-treatment-of-avascular-necrosis-of-the-femoral-head-after-pediatric-femoral-neck-fracture-a-case-report
#11
Ha Yong Kim, Yong Han Cha, Won Sik Choy, Sang Wook Jeung, Yeon Seung Min
This research focuses on femoral head wedge resection for the treatment of avascular necrosis (AVN) of the femoral head. A 9-year-old girl presented to the emergency room complaining of right hip pain that occurred after a pedestrian car accident. After 8 months of internal fixation using cannulated screws for Delbet-type 2 fracture of the femoral neck, AVN of the femoral head developed in the patient. Even though valgus-derotation-extension intertrochanteric osteotomy was performed for the treatment of AVN, it progressed further and femoral head wedge resection was performed to recover the femoral head sphericity...
May 2018: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/29566686/synthesis-of-avenanthramides-using-engineered-escherichia-coli
#12
Su Jin Lee, Geun Young Sim, Hyunook Kang, Won Seok Yeo, Bong-Gyu Kim, Joong-Hoon Ahn
BACKGROUND: Hydroxycinnamoyl anthranilates, also known as avenanthramides (avns), are a group of phenolic alkaloids with anti-inflammatory, antioxidant, anti-itch, anti-irritant, and antiatherogenic activities. Some avenanthramides (avn A-H and avn K) are conjugates of hydroxycinnamic acids (HC), including p-coumaric acid, caffeic acid, and ferulic acid, and anthranilate derivatives, including anthranilate, 4-hydroxyanthranilate, and 5-hydroxyanthranilate. Avns are primarily found in oat grain, in which they were originally designated as phytoalexins...
March 22, 2018: Microbial Cell Factories
https://www.readbyqxmd.com/read/29564212/neglected-traumatic-hip-dislocation-influence-of-the-increased-intracapsular-pressure
#13
Elsayed Ibraheem Elsayed Massoud
AIM: To investigate that the increased intracapsular pressure, during the delay period, can interrupt the blood flow to the femoral head. METHODS: An observational retrospective study included a group of 17 patients with traumatic hip dislocation, their ages at time of injury averaged 26 (range from 3 to 70) years. Outcomes were assessed clinically and radiographically at a period averaged 11.5 (range from 4 to 20) years. RESULTS: Minor trauma caused dislocation in seven and severe trauma in ten patients...
March 18, 2018: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29555896/talar-neck-fracture-with-dislocation-combined-with-bimalleolar-ankle-fracture-a-case-report
#14
Ahmad M Radaideh, Ziad A Audat, Abdullah A Saleh
BACKGROUND Fractures of the talus are uncommon injuries that usually involve the talar neck, rather than the talar body. This report is of a rare case of combined left talar neck fracture and adjacent joint dislocation with an ipsilateral bimalleolar ankle fracture. CASE REPORT A 37-year-old man presented with an injury to his left foot following a motor vehicle accident. When he presented to the hospital emergency department, his left foot and ankle were swollen, the overlying skin was intact but badly contused, and there was no neurovascular deficit...
March 20, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29541270/early-results-of-the-a-l-p-s-proximal-humerus-locking-plate
#15
Miltiadis Argyropoulos, Matthew Kent
Background: Open reduction internal fixation of displaced 3 and 4-part proximal humerus fractures is an effective treatment modality particularly for the younger age group, but it is not without complications. Fixed angled locking screw plates are the mainstay of fixation. The A.L.P.S. Proximal Humerus Plating System is a new implant that has smooth locking pegs in the place of humeral head screws to help reduce glenoid damage in the event of cut-out and is designed to sit low on the humerus in order to reduce the risk of subacromial impingement...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29537314/custom-3d-printed-total-talar-prostheses-restore-normal-joint-anatomy-throughout-the-hindfoot
#16
Joseph Tracey, Danny Arora, Christopher E Gross, Selene G Parekh
BACKGROUND: Third generation total talar prostheses (TTPs) are viable options for talar avascular necrosis (AVN) in the absence of neighboring joint pathology. The use of modern three-dimensional (3D) printing allows the production of custom implants that exactly mimic the patient's anatomy. The aim of this study is to determine the accuracy of 3D printing in reproducing a synthetic talus and, in doing so, restoring more normal anatomical relationships. We hypothesize that this mode of replication will restore and maintain normal radiographic alignment of the ankle, subtalar, and forefoot joints in the setting of talar AVN...
March 1, 2018: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/29515680/transosseous-suture-fixation-of-true-4-part-valgus-impacted-fractures-of-the-proximal-humerus-clinical-and-radiological-outcome-in-49-patients
#17
Andreas Panagopoulos, Irini Tatani, Seferlis Yannis, Bavelou Aikaterini, Antonis Kouzelis, Minos Tyllianakis, Panayotis Dimakopoulos
Background: The valgus-impacted (VI) 4-part fractures are a subset of fractures of the proximal humerus with a unique anatomic configuration characterized by a relatively lower incidence of avascular necrosis after operative intervention. Objectives: The present study reports the midterm clinical and radiological results of a large series of consecutive patients with 4-part VI fractures treated with a minimal invasive technique of internal fixation. Methods: Over a ten-year period (2004-2014), we treated 56 patients with a true 4-part valgus impacted fracture of the proximal part of the humerus...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29502127/detection-of-acute-myocardial-infarction-in-a-pig-model-using-the-san-atrial-avn-his-saah-electrocardiogram-ecg-model-phs-a10-an-automated-and-integrated-signals-recognition-system
#18
Wenjiao Zhao, Guihua Lu, Li Liu, Zhishan Sun, Mingxin Wu, Wenyan Yi, Haiyan Chen, Yanhui Li, Lilong Tang, Jianping Zeng
BACKGROUND The aim of this study was to compare the use of the standard 12-lead electrocardiogram (ECG) with the SAN-Atrial-AVN-His (SAAH) ECG (Model PHS-A10), a new automated and integrated signals recognition system that detects micro-waveforms within the P, QRS, and T-wave, in a pig model of acute myocardial infarction (MI). MATERIAL AND METHODS Six medium-sized domestic Chinese pigs underwent general anesthesia, and an angioplasty balloon was placed and dilated for 120 minutes in the first diagonal coronary artery arising from the left anterior descending (LAD) coronary artery...
March 4, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29496606/safety-and-feasibility-of-leadless-pacemaker-in-patients-undergoing-atrioventricular-node-ablation-for-atrial-fibrillation
#19
Bharath Yarlagadda, Mohit K Turagam, Tawseef Dar, Pragna Jangam, Vaishnavi Veerapaneni, Donita Atkins, Sudharani Bommana, Paul Friedman, Abhishek J Deshmukh, Rahul Doshi, Vivek Y Reddy, Srinivas R Dukkipati, Andrea Natale, Dhanunjaya Lakkireddy
BACKGROUND: Atrioventricular node (AVN) ablation and permanent pacing is an established strategy for rate control in the management of symptomatic atrial fibrillation (AF). Leadless pacemakers (LPs) can overcome some of the short-term and long-term limitations of conventional transvenous pacemakers (CTPs). OBJECTIVES: The purpose of this study was to compare the feasibility and safety of LP with those of single-chamber CTP in patients with AF undergoing AVN ablation...
March 1, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29478323/identification-and-quantification-of-avenanthramides-and-free-and-bound-phenolic-acids-in-eight-cultivars-of-husked-oat-avena-sativa-l-from-finland
#20
Salvatore Multari, Juha-Matti Pihlava, Priscilla Ollennu-Chuasam, Veli Hietaniemi, Baoru Yang, Jukka-Pekka Suomela
Finland is the second largest oat producer in Europe. Despite the existing knowledge of phenolics in oat, there is little information on the phenolic composition of oats from Finland. The aim of the study was to investigate the concentrations of free and bound phenolic acids, as well as avenanthramides in eight Finnish cultivars of husked oat ( Avena sativa L.). Seven phenolic acids and one phenolic aldehyde were identified, including, in decreasing order of abundance: p-coumaric, ferulic, cinnamic, syringic, vanillic, 2,4-dihydroxybenzoic, and o-coumaric acids and syringaldehyde...
March 21, 2018: Journal of Agricultural and Food Chemistry
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