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procalcitonin sensitivity

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https://www.readbyqxmd.com/read/28639554/evaluation-of-procalcitonin-and-hs-crp-levels-in-sudden-sensorineural-hearing-loss
#1
Sercan Göde, Göksel Turhal, İsa Kaya, Halil İbrahim Mavili, Tayfun Kirazlı
OBJECTIVE: The aim of this study was to evaluate procalcitonin and high sensitive c-reactive protein (hs-CRP) levels in idiopathic sudden sensorineural hearing loss (ISSNHL) patients and assess their correlations with the clinical prognosis. MATERIALS AND METHODS: Twenty-three ISSNHL patients were included in the study (group A). The control group was consisted of 19 patients (group B). Procalcitonin and hs-CRP levels were compared between the groups. The relationship between procalcitonin and hs-CRP levels and the configuration of the audiogram, degree of hearing loss [partial or total (>90 dB)], and status of improvement (improvement of > 15 dB in the first month PTA) were evaluated...
June 21, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28625262/-predictive-value-of-sofa-score-combined-agi-grading-system-in-elderly-patients-with-sepsis-a-retrospective-analysis-with-91-patients
#2
Lingling Wang, Rui Chen, Zexun Mo, Jiahui Dong, Zhaokun Sun, Fei Xiao, Shaoting Hu, Richeng Xiong, Jie Sun, Zhou Yu, Zhenhui Guo
OBJECTIVE: To explore the predictive value of sequential organ failure assessment (SOFA) score combined the acute gastrointestinal injury (AGI) grading system in critical elderly patients with sepsis. METHODS: A retrospective analysis was conducted. Elderly patients with sepsis aged > 60 years admitted to medical intensive care unit (MICU) of General Hospital of Guangzhou Military Command from March 2014 to December 2015 and experiencing critical care over 48 hours were enrolled...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28625261/-formulation-of-combined-predictive-indicators-using-logistic-regression-model-in-predicting-sepsis-and-prognosis
#3
Liwei Duan, Sheng Zhang, Zhaofen Lin
OBJECTIVE: To explore the method and performance of using multiple indices to diagnose sepsis and to predict the prognosis of severe ill patients. METHODS: Critically ill patients at first admission to intensive care unit (ICU) of Changzheng Hospital, Second Military Medical University, from January 2014 to September 2015 were enrolled if the following conditions were satisfied: (1) patients were 18-75 years old; (2) the length of ICU stay was more than 24 hours; (3) All records of the patients were available...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28625258/-plasma-level-of-neutrophil-extracellular-traps-in-septic-patients-and-its-clinical-significance-a-prospective-observational-study
#4
Fangxiao Zhang, Zhidan Zhang, Xiaochun Ma
OBJECTIVE: To investigate the changes of neutrophil extracellular traps (NETs) level in plasma of sepsis patients and judge its clinical value for early diagnosing of sepsis. METHODS: A prospective observational study was conducted. The patients after surgery aged > 18 years and expected to stay in the ICU > 24 hours admitted to intensive care unit (ICU) of the First Affiliated Hospital of China Medical University from November 2014 to February 2015 were enrolled...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28625236/-eosinophil-could-predict-the-prognosis-of-patients-with-bloodstream-infection-a-retrospective-analysis-of-305-cases
#5
Duan Guo, Chao Jia, Hang Su
OBJECTIVE: To investigate the value of peripheral blood for the prognosis of patients with bloodstream infection. METHODS: A retrospective analysis of patients with bloodstream infection was conducted in the intensive care unit (ICU) of Mianyang Central Hospital of Sichuan from January 2012 to October 2016. According to the 28-day survival, the patients were divided into survival group and death group. The white blood cell (WBC), neutrophils count (NEU), lymphocyte count (LYM), neutrophil/lymphocyte ratio (NLR), monocyte count (MO), eosinophil count (EO), basophil count (BA), hemoglobin (Hb), platelet count (PLT) and procalcitonin (PCT) in peripheral blood were recorded when patients were diagnosed with blood infection...
June 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28623003/serum-procalcitonin-levels-as-a-diagnostic-marker-for-septic-arthritis-a-meta-analysis
#6
Jingyi Zhao, Shufeng Zhang, Lei Zhang, Xianhui Dong, Jianhui Li, Ying Wang, Yinhui Yao
BACKGROUND: The aim of this study was to assess the value of serum procalcitonin (PCT) levels as a diagnostic marker for septic arthritis (SA) via meta-analysis. METHODS: We searched PubMed, Embase and the Cochrane Library, as well as the reference lists of relevant articles, for studies published up to May 21, 2015 and did not impose language restrictions. We selected original studies reporting the usefulness of PCT or C-reactive protein (CRP) as a diagnostic marker for SA...
June 7, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28616918/-value-of-procalcitonin-high-sensitivity-c-reactive-protein-and-pancreatic-stone-protein-in-predicting-prognosis-of-children-with-sepsis
#7
Jun-Ming Huo, Rui Huo, Ling Hu, Si-Wei Lu, Jian Zu
OBJECTIVES: To determine the value of procalcitonin (PCT), high sensitivity C-reactive protein (hs-CRP) and pancreatic stone protein(PSP) in predicting the prognosis of children with sepsis. METHODS: A total of 106 hospitalized children [(4.4±1.6) year-old] with sepsis were enrolled in this study. The expressions of PTC, hs-CRP and PSP in the serum samples of the children were detected on the first day of admission to hospital. Pearson correlation analyses were performed to test the correlations between pediatric critical illness score (PCIS) and PTC, hs-CRP and PSP...
May 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28614777/increased-circulating-endocan-in-patients-with-cirrhosis-relation-to-bacterial-infection-and-severity-of-disease
#8
J Zuwala-Jagiello, K Simon, M Kukla, E Murawska-Cialowicz, J Gorka-Dynysiewicz, E Grzebyk, M Pazgan-Simon
Life expectancy of patients with liver cirrhosis is closely linked to the degree of liver dysfunction and the occurrence of bacterial infection. An early diagnosis of infection helps to initiate adequate and timely measures and improves outcome of cirrhotic patients. Endocan is a newly recognized biomarker of sepsis. However, there have been no studies of the trends in endocan levels in cirrhotic patients with bacterial infection and their associations with markers of infection and inflammation. This study sought to assess the diagnostic value of serum levels of endocan, procalcitonin (PCT), C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) in 126 patients with cirrhosis: 51 with decompensated infected cirrhosis, 56 with decompensated uninfected and 19 with compensated uninfected cirrhosis at inclusion...
April 2017: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/28614698/sardine-procalcitonin-amino-terminal-cleavage-peptide-has-a-different-action-from-calcitonin-and-promotes-osteoblastic-activity-in-the-scales-of-goldfish
#9
Yoichi Kase, Takahiro Ikari, Toshio Sekiguchi, Masayuki Sato, Shouzo Ogiso, Tsuyoshi Kawada, Shin Matsubara, Honoo Satake, Yuichi Sasayama, Masato Endo, Kei-Ichiro Kitamura, Atsuhiko Hattori, Takushi X Watanabe, Yusuke Maruyama, Yoshinari Watanabe, Hisayuki Funahashi, Akira Kambegawa, Nobuo Suzuki
The nucleotide sequence of a sardine preprocalcitonin precursor has been determined from their ultimobranchial glands in the present study. From our analysis of this sequence, we found that sardine procalcitonin was composed of procalcitonin amino-terminal cleavage peptide (N-proCT) (53 amino acids), CT (32 amino acids), and procalcitonin carboxyl-terminal cleavage peptide (C-proCT) (18 amino acids). As compared with C-proCT, N-proCT has been highly conserved among teleosts, reptiles, and birds, which suggests that N-proCT has some bioactivities...
June 11, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28596927/necrotizing-pseudomonas-aeruginosa-community-acquired-pneumonia-a-case-report-and-review-of-the-literature
#10
Satish Maharaj, Carmen Isache, Karan Seegobin, Simone Chang, Grant Nelson
Lung cavities are not typically associated with community-acquired pneumonia (CAP). CAP due to P. aeruginosa is rare and even less commonly causes necrotizing pneumonia. We report a case of P. aeruginosa CAP that progressed to necrotizing pneumonia and was eventually fatal. Procalcitonin (PCT) has been well investigated in guiding antibiotic therapy (especially CAP) in adults. In this case, PCT at presentation and sequentially was negative. We discuss this caveat and present hypotheses as to the sensitivity and specificity of PCT and C-reactive protein (CRP) in these patients...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28593411/c-reactive-protein-fibrinogen-and-procalcitonin-levels-as-early-markers-of-staple-line-leak-after-laparoscopic-sleeve-gastrectomy-in-morbidly-obese-patients-within-an-enhanced-recovery-after-surgery-eras-program
#11
Jaime Ruiz-Tovar, Jose Luis Muñoz, Juan Gonzalez, Alejandro Garcia, Carlos Ferrigni, Montiel Jimenez, Manuel Duran
INTRODUCTION: The performance of most bariatric procedures within an Enhanced Recovery After Surgery program has resulted in significant advantages, including a reduction in the length of hospital stay to 2-3 days. However, some postoperative complications may appear after the patient has been discharged. The aim of this study was to investigate the efficacy of various acute-phase parameters determined 24 h after a laparoscopic sleeve gastrectomy for predicting staple line leak in the postoperative course...
June 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28587429/variation-in-the-levels-of-il-6-in-pediatric-patients-with-severe-bacterial-infectious-diseases-and-correlation-analysis-between-the-levels-of-il-6-and-procalcitonin
#12
Fangfang Bian, Yue-E Wu, Chong-Lin Zhang
The objective of the present study was to investigate variations in the levels of interleukin (IL)-6, procalcitonin (PCT), and C-reactive protein (CRP) in children with severe bacterial infectious diseases and to analyze the correlation between the levels of IL-6 and PCT to determine the value of combined diagnosis with IL-6 and PCT. We analyzed 126 patients admitted to Xuzhou Children's Hospital for treatment, who were divided into severe bacterial infection (observation group, n=65) and non-bacterial infection groups (control group, n=61)...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28587428/early-diagnosis-of-bacterial-infection-in-patients-with-septicopyemia-by-laboratory-analysis-of-pct-crp-and-il-6
#13
Liqin Gao, Xinghui Liu, Denghai Zhang, Fengxia Xu, Qing Chen, Ye Hong, Gang Feng, Qin Shi, Bin Yang, Limin Xu
The aim of the present study was to investigate the early diagnostic values of measuring procalcitonin (PCT), C-reactive protein (CRP), and interleukin-6 (lL-6) levels in patients with bacterial infections and septicopyemia. Ninety-two patients with septicopyemia who were diagnosed and treated in the First Affiliated Hospital of Fujian Medical University between December 2012 and October 2013 were randomly selected. Based on results of hemoculture, the patients were divided into the Gram-negative bacterial infection group (n=47) and the Gram-positive bacterial infection group (n=45)...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28587330/principles-of-antibiotic-application-in-children-with-lobar-pneumonia-step-up-or-step-down
#14
Yan Li, Feng Han, Yan Yang, Jianwei Chu
In order to provide a scientific basis for rational use of antibiotics, we studied and compared the therapeutic effects of step-down and step-up antibiotic treatment schemes in children with lobar pneumonia. Eighty cases of children with lobar pneumonia were enrolled in this study and were randomly divided into two groups: The observation group and the control group, with 40 cases in each group. In the observation group, there were 23 cases with mild and 17 cases with severe lobar pneumonia, and in the control group, 25 were mild and 15 were severe cases...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28585679/diagnostic-value-of-selected-biochemical-markers-in-the-detection-of-recurrence-of-medullary-thyroid-cancer-comparison-of-calcitonin-procalcitonin-chromogranin-a-and-carcinoembryonic-antigen
#15
Kosma Woliński, Jarosław Kaznowski, Aleksandra Klimowicz, Adam Maciejewski, Dagny Łapińska-Cwojdzińska, Edyta Gurgul, Adrian D Car, Marta Fichna, Paweł Gut, Maria Gryczyńska, Marek Ruchała
INTRODUCTION: Medullary thyroid cancer (MTC) is a malignancy of the thyroid gland, which derives from parafollicular C cells. Periodic measurement of biochemical markers of MTC remains a crucial part of patient follow-up and disease monitoring. The aim of the study was to compare the diagnostic value of four selected markers - calcitonin (Ct), procalcitonin (PCT), chromogranin A (CgA), and carcinoembryonic antigen (CEA). METHODS: Patients with histopathologically confirmed MTC hospitalised in a single department between January 2015 and December 2015 were included in the study...
June 6, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/28580081/the-prognostic-value-of-procalcitonin-c-reactive-protein-and-cholesterol-in-patients-with-an-infection-and-multiple-organ-dysfunction
#16
Siarhei Anatolevich Tachyla, Alexey Viktorovich Marochkov, Artur Leonidovich Lipnitski, Yulia Gennadevna Nikiforova
BACKGROUND: To establish the prognostic value of procalcitonin, C-reactive protein and cholesterol levels for mortality in patients with an infection and multiple organ dysfunction. METHODS: A prospective case-control study was performed, including 67 patients admitted to the intensive care unit with an infection and multiple organ dysfunction in whom cholesterol, procalcitonin, and C-reactive protein levels were measured on admission and during the course of treatment...
June 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28553881/the-relationship-between-levels-of-plasma-soluble-urokinase-plasminogen-activator-receptor-supar-and-presence-of-migraine-attack-and-aura
#17
Nigar Yılmaz, Mustafa Yılmaz, Burcu Sirin, Sureyya Yılmaztekin, Gülnihal Kutlu
Migraine is one of the most common types of pain associated with sterile inflammatory conditions. Soluble urokinase plasminogen activator receptor (suPAR) is a potential novel inflammatory marker. We aim to determine the association between serum values of suPAR, procalcitonin, fibrinogen, and high-sensitivity C-reactive protein (hs-CRP) and migraine disease characteristics. The study involved a total of 60 migraine patients (33 patients in the interictal period, 27 patients in the attack period) and 30 healthy individuals...
May 29, 2017: Journal of Receptor and Signal Transduction Research
https://www.readbyqxmd.com/read/28552399/evaluation-of-lactate-white-blood-cell-count-neutrophil-count-procalcitonin-and-immature-granulocyte-count-as-biomarkers-for-sepsis-in-emergency-department-patients
#18
Brad S Karon, Nicole V Tolan, Amy M Wockenfus, Darci R Block, Nikola A Baumann, Sandra C Bryant, Casey M Clements
BACKGROUND: Lactate, white blood cell (WBC) and neutrophil count, procalcitonin and immature granulocyte (IG) count were compared for the prediction of sepsis, and severe sepsis or septic shock, in patients presenting to the emergency department (ED). METHODS: We prospectively enrolled 501 ED patients with a sepsis panel ordered for suspicion of sepsis. WBC, neutrophil, and IG counts were measured on a Sysmex XT-2000i analyzer. Lactate was measured by i-STAT, and procalcitonin by Brahms Kryptor...
May 25, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28548632/diagnostic-and-prognostic-value-of-inflammatory-parameters-including-neopterin-in-the-setting-of-pneumonia-copd-and-acute-exacerbations
#19
Alex Pizzini, Fabian Lunger, Amra Sahanic, Nada Nemati, Dietmar Fuchs, Günter Weiss, Katharina Kurz, Rosa Bellmann-Weiler
Acute exacerbations and community-acquired pneumonia (CAP) are severe complications in patients with chronic obstructive pulmonary disease (COPD). In this study, we analyzed inflammatory parameters in serum including C-reactive protein (CRP), procalcitonin (PCT), and serum neopterin (NPT) to determine their potential to differentiate between patients with CAP+COPD and with acute exacerbations of COPD (AECOPD) without pneumonia. 102 (39 women and 63 men) patients were included in this retrospective study, of whom 48 presented with CAP without underlying COPD, 20 with CAP+COPD and 34 with AECOPD...
June 2017: COPD
https://www.readbyqxmd.com/read/28541274/cerebrospinal-fluid-procalcitonin-as-a-biomarker-of-bacterial-meningitis-in-neonates
#20
Z Reshi, M Nazir, W Wani, M Malik, J Iqbal, S Wajid
OBJECTIVE: The objective of the study was to study the performance of cerebrospinal fluid (CSF) procalcitonin as a marker for bacterial meningitis in neonates, and to determine its optimal 'cutoff' in CSF that can be called significant for the diagnosis. STUDY DESIGN: Neonates qualifying for lumbar puncture were prospectively studied. Procalcitonin and established CSF parameters were recorded. RESULTS: At a cut-off value of 0.33 ng ml(-1), CSF procalcitonin had a sensitivity of 0...
May 25, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
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