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pain neuroscience

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https://www.readbyqxmd.com/read/27903159/recognition-and-treatment-of-central-sensitization-in-chronic-pain-patients-not-limited-to-specialized-care
#1
Jo Nijs, Dorien Goubert, Kelly Ickmans
Modern pain neuroscience has substantially improved our understanding of the (development of) chronic musculoskeletal pain. The time has come for orthopaedic and sports physical therapists to implement modern pain neuroscience in specialized, but definitely also in primary, care settings, including the role of central sensitization (CS) in amplifying and explaining the presence of the pain experience. Central sensitization dominates the clinical picture in a subgroup of the musculoskeletal pain population, ranging from tennis elbow over shoulder pain to osteoarthritis and whiplash...
December 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27887679/-mindfulness-based-interventions-in-obsessive-compulsive-disorder-mechanisms-of-action-and-presentation-of-a-pilot-study
#2
M Gasnier, A Pelissolo, G Bondolfi, S Pelissolo, M Tomba, L Mallet, K N'diaye
Obsessive-compulsive disorder (OCD) is a frequent and severe disease, potentially inducing a major impairment for the patient and burden for their family. Recent research in psychiatry and neuroscience have led to better comprehension of the disease's mechanisms and helped to improve its treatment. However, a large proportion of patients have refractory symptoms, including for traditional cognitive and behavioral therapy by exposure and response prevention (ERP), leading clinicians to look for new treatments...
November 22, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27885658/early-skin-to-skin-contact-for-mothers-and-their-healthy-newborn-infants
#3
REVIEW
Elizabeth R Moore, Nils Bergman, Gene C Anderson, Nancy Medley
BACKGROUND: Mother-infant separation post birth is common. In standard hospital care, newborn infants are held wrapped or dressed in their mother's arms, placed in open cribs or under radiant warmers. Skin-to-skin contact (SSC) begins ideally at birth and should last continually until the end of the first breastfeeding. SSC involves placing the dried, naked baby prone on the mother's bare chest, often covered with a warm blanket. According to mammalian neuroscience, the intimate contact inherent in this place (habitat) evokes neuro-behaviors ensuring fulfillment of basic biological needs...
November 25, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27790160/the-neuropsychoanalytic-approach-using-neuroscience-as-the-basic-science-of-psychoanalysis
#4
Brian Johnson, Daniela Flores Mosri
Neuroscience was the basic science behind Freud's psychoanalytic theory and technique. He worked as a neurologist for 20 years before being aware that a new approach to understand complex diseases, namely the hysterias, was needed. Solms coined the term neuropsychoanalysis to affirm that neuroscience still belongs in psychoanalysis. The neuropsychoanalytic field has continued Freud's original ideas as stated in 1895. Developments in psychoanalysis that have been created or revised by the neuropsychoanalysis movement include pain/relatedness/opioids, drive, structural model, dreams, cathexis, and dynamic unconscious...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27720917/tetrahydrocannabinol-does-not-reduce-pain-in-patients-with-chronic-abdominal-pain-in-a-phase-2-placebo-controlled-study
#5
Marjan de Vries, Dagmar C M van Rijckevorsel, Kris C P Vissers, Oliver H G Wilder-Smith, Harry van Goor
BACKGROUND & AIMS: Delta-9-atetrahydrocannabinol (THC) is the most abundant cannabinoid from the plant Cannabis sativa. There is only equivocal evidence that THC has analgesic effects. We performed a phase 2 controlled trial to evaluate the analgesic efficacy, pharmacokinetics, safety, and tolerability of an oral tablet containing purified THC in patients with chronic abdominal pain. METHODS: Sixty-five patients with chronic abdominal pain for 3 months or more (numeric rating scale scores of 3 or more) after surgery or because of chronic pancreatitis were randomly assigned to groups given the THC tablet or identical matching placebos for 50-52 days...
October 5, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27719874/nature-of-the-placebo-and-nocebo-effect-in-relation-to-functional-neurologic-disorders
#6
E Carlino, A Piedimonte, F Benedetti
Placebos have long been considered a nuisance in clinical research, for they have always been used as comparators for the validation of new treatments. By contrast, today they represent an active field of research, and, due to the involvement of many mechanisms, the study of the placebo effect can actually be viewed as a melting pot of concepts and ideas for neuroscience. There is not a single placebo effect, but many, with different mechanisms across different medical conditions and therapeutic interventions...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27696337/the-psycho-neurology-of-cross-species-affective-social-neuroscience-understanding-animal-affective-states-as-a-guide-to-development-of-novel-psychiatric-treatments
#7
Jaak Panksepp
During the past half century of research with preclinical animal models, affective neuroscience has helped identify and illuminate the functional neuroanatomies and neurochemistries of seven primary process, i.e., genetically provided emotional systems of mammalian brains. All are subcortically localized, allowing animal models to guide the needed behavioral and neuroscientific analyses at levels of detail that cannot be achieved through human research, including modern brain imaging. They consist of the following neuronal processes: SEEKING/Enthusiasm, RAGE/Anger, FEAR/Anxiety, sexual LUST/Passion, maternal CARE/Nurturance, separation-distress PANIC/Grief and PLAY/Social Joy...
October 2, 2016: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/27676667/subtle-sensory-abnormalities-detected-by-quantitative-sensory-testing-in-patients-with-trigeminal-neuralgia
#8
Herta Flor, Dirk Rasche, Ariyan Pirayesh Islamian, Claudia Rolko, Pinar Yilmaz, Marc Ruppolt, H Holger Capelle, Volker Tronnier, Joachim K Krauss
BACKGROUND: Trigeminal neuralgia (TN) is characterized by paroxysmal pain attacks affecting the somatosensory distributions of the trigeminal nerve. It is thought to be associated with a neurovascular conflict most frequently, but pathomechanisms have not been fully elucidated. In general, no sensory deficit is found in routine clinical examination. There is limited data available, however, showing subtle subclinical sensory deficits upon extensive testing. OBJECTIVE: We used quantitative sensory testing (QST) to detect abnormalities in sensory processing in patients with TN by comparing the affected and non-affected nerve branches with their contralateral counterparts and by comparing the results of the patients with those of controls...
September 2016: Pain Physician
https://www.readbyqxmd.com/read/27498037/animal-models-of-resistance-exercise-and-their-application-to-neuroscience-research
#9
REVIEW
Justin C Strickland, Mark A Smith
BACKGROUND: Numerous studies have demonstrated that participation in regular resistance exercise (e.g., strength training) is associated with improvements in mental health, memory, and cognition. However, less is known about the neurobiological mechanisms mediating these effects. The goal of this mini-review is to describe and evaluate the available animal models of resistance exercise that may prove useful for examining CNS activity. NEW METHOD: Various models have been developed to examine resistance exercise in laboratory animals...
November 1, 2016: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/27485952/consensus-paper-cerebellum-and-emotion
#10
M Adamaszek, F D'Agata, R Ferrucci, C Habas, S Keulen, K C Kirkby, M Leggio, P Mariën, M Molinari, E Moulton, L Orsi, F Van Overwalle, C Papadelis, A Priori, B Sacchetti, D J Schutter, C Styliadis, J Verhoeven
Over the past three decades, insights into the role of the cerebellum in emotional processing have substantially increased. Indeed, methodological refinements in cerebellar lesion studies and major technological advancements in the field of neuroscience are in particular responsible to an exponential growth of knowledge on the topic. It is timely to review the available data and to critically evaluate the current status of the role of the cerebellum in emotion and related domains. The main aim of this article is to present an overview of current facts and ongoing debates relating to clinical, neuroimaging, and neurophysiological findings on the role of the cerebellum in key aspects of emotion...
August 2, 2016: Cerebellum
https://www.readbyqxmd.com/read/27468610/-effect-of-instrumental-surgical-fusion-on-the-quality-of-life-in-degenerative-spondylolisthesis
#11
Enikő Sáró, Ferenc Misik, Péter Banczerowski
OBJECTIVE: There is no internationally accepted guideline for treatment of spondylolisthesis in the literature, otherwise this degenerative disease has great social and economical impact. There is no hungarian study examining the efficacy of instrumented fusion procedure in surgical treatment of spondylolisthesis. In current study we examined the effectiveness of fusion technique focusing on the impact of quality of life. METHODS: Between 1st January, 2011 and 30th June, 2012 we examined a group of patients--who were operated on by instrumented fusion technique because of spondylolisthesis--, in the National Institute of Clinical Neurosciences, using the Oswestry Low Back Disability Questionnaire...
March 30, 2016: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/27461519/corrigendum-to-neuropathic-pain-induced-by-spinal-cord-injury-role-of-endothelin-eta-and-etb-receptors-neurosci-lett-617-2016-14-21
#12
S Forner, A C Martini, E L Andrade, G A Rae
No abstract text is available yet for this article.
July 23, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27456330/referrals-to-integrative-medicine-in-a-tertiary-hospital-findings-from-electronic-health-record-data-and-qualitative-interviews
#13
Kristen H Griffin, Kent C Nate, Rachael L Rivard, Jon B Christianson, Jeffery A Dusek
OBJECTIVE: To examine patterns of, and decision-making processes, informing referrals for inpatient access to integrative medicine (IM) services at a large, acute care hospital. DESIGN: Retrospective electronic health record review and structured qualitative interviews. SETTING: A 630-bed tertiary care hospital with an IM service available to inpatients. PARTICIPANTS: IM referrals of all inpatients aged ≥18 years between July 2012 and December 2014 were identified using the hospital's electronic health record...
2016: BMJ Open
https://www.readbyqxmd.com/read/27445835/atp1a2-mutations-in-migraine-seeing-through-the-facets-of-an-ion-pump-onto-the-neurobiology-of-disease
#14
REVIEW
Thomas Friedrich, Neslihan N Tavraz, Cornelia Junghans
Mutations in four genes have been identified in familial hemiplegic migraine (FHM), from which CACNA1A (FHM type 1) and SCN1A (FHM type 3) code for neuronal voltage-gated calcium or sodium channels, respectively, while ATP1A2 (FHM type 2) encodes the α2 isoform of the Na(+),K(+)-ATPase's catalytic subunit, thus classifying FHM primarily as an ion channel/ion transporter pathology. FHM type 4 is attributed to mutations in the PRRT2 gene, which encodes a proline-rich transmembrane protein of as yet unknown function...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27419354/photobiomodulation-implications-for-anesthesia-and-pain-relief
#15
Roberta T Chow, Patricia J Armati
OBJECTIVE: This review examines the evidence of neural inhibition as a mechanism underlying pain relief and anesthetic effect of photobiomodulation (PBM). BACKGROUND: PBM for pain relief has also been used for more than 30 years; however, the mechanism of its effectiveness has not been well understood. METHODS: We review electrophysiological studies in humans and animal models and cell culture studies to examine neural responses to PBM. RESULTS: Evidence shows that PBM can inhibit nerve function in vivo, in situ, ex vivo, and in culture...
July 15, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27417433/contribution-of-delta-opioid-receptors-to-pathophysiological-events-explored-by-endogenous-enkephalins
#16
Bernard P Roques
Very few discoveries in the neurosciences have triggered clinical speculation and experimentation regarding the etiology of psychiatric illness to the same extent as that following identification of the opiate receptor(s) and subsequent isolation of endogenous morphine-like peptides. There is overwhelming evidence in animals and in human that opioids are involved in behaviorally relevant issues such as the modulation of pain, the response to stress, motivation, addiction, sexuality, food intake, etc., but our knowledge on the possible relation between opioids and mental illness is still very limited...
July 15, 2016: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/27400330/special-issue-perspectives-on-pain-neuroscience-education
#17
Scott Hasson
No abstract text is available yet for this article.
July 2016: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/27385918/-c-r-e-a-t-e-ing-unique-primary-source-research-paper-assignments-for-a-pleasure-and-pain-course-teaching-neuroscientific-principles-in-a-large-general-education-undergraduate-course
#18
Richard J Bodnar, Francis M Rotella, Ilyssa Loiacono, Tricia Coke, Kerstin Olsson, Alicia Barrientos, Lauren Blachorsky, Deena Warshaw, Agata Buras, Ciara M Sanchez, Raihana Azad, James R Stellar
A large (250 registrants) General Education lecture course, Pleasure and Pain, presented basic neuroscience principles as they related to animal and human models of pleasure and pain by weaving basic findings related to food and drug addiction and analgesic states with human studies examining empathy, social neuroscience and neuroeconomics. In its first four years, the course grade was based on weighted scores from two multiple-choice exams and a five-page review of three unique peer-reviewed research articles...
2016: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/27362980/combining-manual-therapy-with-pain-neuroscience-education-in-the-treatment-of-chronic-low-back-pain-a-narrative-review-of-the-literature
#19
Emilio J Puentedura, Timothy Flynn
Teaching people with chronic low back pain (CLBP) about the neurobiology and neurophysiology of their pain is referred to as pain neuroscience education (PNE). There is growing evidence that when PNE is provided to patients with chronic musculoskeletal pain, it can result in decreased pain, pain catastrophization, disability, and improved physical performance. Because the aim of PNE is to shift the patient's focus from the tissues in the low back as the source of their pain to the brain's interpretation of inputs, many clinicians could mistakenly believe that PNE should be a "hands-off," education-only approach...
July 2016: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/27356079/reconciling-movement-and-exercise-with-pain-neuroscience-education-a-case-for-consistent-education
#20
Cory Blickenstaff, Neil Pearson
This article will introduce a conceptual framework of kinesthetic education that is consistent with and reinforces pain neuroscience education. This article will also provide some specific guidance for integrating pain neuroscience education with exercise and movement in a more congruent manner. Our belief is that this will enhance the effectiveness of specific movement approaches such as graded exposure techniques. Over the past decade, a new paradigm of pain education has been explored in an effort to improve patient outcomes...
July 2016: Physiotherapy Theory and Practice
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