keyword
MENU ▼
Read by QxMD icon Read
search

Victor Perez

keyword
https://www.readbyqxmd.com/read/28440768/clinical-and-metabolic-profile-of-patients-with-latent-autoimmune-diabetes-in-adults-in-specialized-care-in-madrid
#1
Alfonso Arranz Martín, Edurne Lecumberri Pascual, Miguel Ángel Brito Sanfiel, Víctor Andía Melero, Lia Nattero Chavez, Iván Sánchez López, Gloria Cánovas Molina, Francisco Arrieta Blanco, Noemí González Perez Del Villar
OBJECTIVE: To report the clinical characteristics of patients with latent autoimmune diabetes in adults (LADA), and to ascertain their metabolic control and associated chronic complications. METHODS: Patients with DM attending specialized medical care in Madrid who met the following criteria: age at diagnosis of DM >30years, initial insulin independence for at least 6months and positive GAD antibodies were enrolled. Clinical profiles, data on LADA diagnosis, associated autoimmunity, C-peptide levels, therapeutic regimen, metabolic control, and presence of chronic complications were analyzed...
January 2017: Endocrinol Diabetes Nutr
https://www.readbyqxmd.com/read/28438995/csilsfm-combines-light-sheet-fluorescence-microscopy-and-coherent-structured-illumination-for-a-lateral-resolution-below-100-nm
#2
Bo-Jui Chang, Victor Didier Perez Meza, Ernst H K Stelzer
Light-sheet-based fluorescence microscopy (LSFM) features optical sectioning in the excitation process. It minimizes fluorophore bleaching as well as phototoxic effects and provides a true axial resolution. The detection path resembles properties of conventional fluorescence microscopy. Structured illumination microscopy (SIM) is attractive for superresolution because of its moderate excitation intensity, high acquisition speed, and compatibility with all fluorophores. We introduce SIM to LSFM because the combination pushes the lateral resolution to the physical limit of linear SIM...
April 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28427292/chemical-analyses-and-in-vitro-and-in-vivo-toxicity-of-fruit-methanol-extract-of-sechium-edule-var-nigrum-spinosum
#3
Itzen Aguiñiga-Sánchez, Jorge Cadena-Íñiguez, Edelmiro Santiago-Osorio, Guadalupe Gómez-García, Víctor Manuel Mendoza-Núñez, Juana Rosado-Pérez, Mirna Ruíz-Ramos, Víctor Manuel Cisneros-Solano, Edgar Ledesma-Martínez, Angel de Jesus Delgado-Bordonave, Ramón Marcos Soto-Hernández
CONTEXT: Sechium edule (Jacq.) Sw. (Cucurbitaceae) is used in ethnomedicine, but the diversity of the varietal groups of this species has not often been considered. This is important because we previously reported that different variety of species exhibit different activities across different tumor cell lines. OBJECTIVE: This study investigates the chemical composition and biological activities of extracts obtained from S. edule var. nigrum spinosum. MATERIALS AND METHODS: The leukemia P388 cell line and mononuclear bone marrow cells (MNCBMs) were treated with the extract at a concentration ranging from 40 to 2370 μg/mL for cytotoxicity and viability assays...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28426442/amniotic-membrane-use-for-management-of-corneal-limbal-stem-cell-deficiency
#4
Alfonso L Sabater, Victor L Perez
PURPOSE OF REVIEW: The current article reviews the most recent surgical techniques for management of corneal limbal stem cell deficiency (LSCD) using amniotic membrane tissue. RECENT FINDINGS: Early successes with amniotic membrane transplantation (AMT) for the treatment of ocular surface disorders have encouraged clinicians to investigate new applications. The use of AMT as a temporary patch in emergency cases in which LSCD may develop has considerably improved the prognosis of these patients...
April 19, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28420367/rationale-and-methods-of-the-ifightdepression-study-a-double-blind-randomized-controlled-trial-evaluating-the-efficacy-of-an-internet-based-self-management-tool-for-moderate-to-mild-depression
#5
Azucena Justicia, Matilde Elices, Ana Isabel Cebria, Diego J Palao, Jesús Gorosabel, Dolors Puigdemont, Javier de Diego-Adeliño, Andrea Gabilondo, Alvaro Iruin, Ulrich Hegerl, Víctor Pérez
BACKGROUND: During the last decade online interventions have emerged as a promising approach for patients with mild/moderate depressive symptoms, reaching at large populations and representing cost-effective alternatives. The main objective of this double-blind, randomized controlled trial is to examine the efficacy of an internet-based self-management tool (iFightDepression) for mild to moderate depression as an add-on to treatment as usual (TAU) versus internet-based psychoeducation plus TAU...
April 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28416565/cingulo-insular-structural-alterations-associated-with-psychogenic-symptoms-childhood-abuse-and-ptsd-in-functional-neurological-disorders
#6
David L Perez, Nassim Matin, Arthur Barsky, Victor Costumero-Ramos, Sara J Makaretz, Sigrid S Young, Jorge Sepulcre, W Curt LaFrance, Matcheri S Keshavan, Bradford C Dickerson
OBJECTIVE: Adverse early-life events are predisposing factors for functional neurological disorder (FND) and post-traumatic stress disorder (PTSD). Cingulo-insular regions are implicated in the biology of both conditions and are sites of stress-mediated neuroplasticity. We hypothesised that functional neurological symptoms and the magnitude of childhood abuse would be associated with overlapping anterior cingulate cortex (ACC) and insular volumetric reductions, and that FND and PTSD symptoms would map onto distinct cingulo-insular areas...
April 17, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28412088/tobacco-smoking-and-its-association-with-cognition-in-first-episode-psychosis-patients
#7
Lauren M Hickling, Rocio Perez-Iglesias, Victor Ortiz-García de la Foz, Vincent Balanzá-Martínez, Philip McGuire, Benedicto Crespo-Facorro, Rosa Ayesa-Arriola
Available evidence suggests that nicotine may enhance cognitive functioning. Moreover, it has been suggested that the high prevalence of smoking in people with schizophrenia is in part due to self-medication behaviour to alleviate cognitive deficits. We assessed the association between tobacco smoking and cognitive functioning in a large population of first episode psychosis (FEP) patients (n=304) and healthy controls (n=156). Smokers were not tobacco deprived, or were minimally deprived (≤2h). Verbal memory, visual memory, working memory, processing speed, executive function, motor dexterity and attention were assessed...
April 12, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28408672/the-genome-sequence-of-avibacterium-paragallinarum-strain-cl-has-a-large-repertoire-of-insertion-sequence-elements
#8
Guillermo Horta-Valerdi, Maria Patricia Sanchez-Alonso, Victor M Perez-Marquez, Erasmo Negrete-Abascal, Sergio Vaca-Pacheco, Ismael Hernandez-Gonzalez, Zulema Gomez-Lunar, Gabriela Olmedo-Álvarez, Candelario Vázquez-Cruz
The draft genome sequence of Avibacterium paragallinarum strain CL serovar C is reported here. The genome comprises 154 contigs corresponding to 2.4 Mb with 41% G+C content and many insertion sequence (IS) elements, a characteristic not previously reported in A. paragallinarum.
April 13, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28403219/incidental-hepatocellular-carcinoma-after-liver-transplantation-prevalence-histopathological-features-and-prognostic-impact
#9
Pablo Pérez, Manuel Rodríguez-Perálvarez, Lourdes Guerrero, Víctor González, Rafael Sánchez, Macarena Centeno, Antonio Poyato, Javier Briceño, Marina Sánchez-Frías, Jose Luis Montero, Manuel De la Mata
BACKGROUND: Incidental hepatocellular carcinoma (iHCC) is a histological finding after liver transplantation (LT) which relevance has been scarcely studied. AIMS: to describe the histopathological features of iHCC and to determine its prognostic impact in terms of tumor recurrence and overall survival. METHODS: Observational study including 451 consecutive adult LT patients (2000-2013). Patients aged<18, retransplanted or with early postoperative death were excluded...
2017: PloS One
https://www.readbyqxmd.com/read/28398330/remote-detection-of-buried-landmines-using-a-bacterial-sensor
#10
Shimshon Belkin, Sharon Yagur-Kroll, Yossef Kabessa, Victor Korouma, Tali Septon, Yonatan Anati, Cheinat Zohar-Perez, Zahi Rabinovitz, Amos Nussinovitch, Aharon J Agranat
No abstract text is available yet for this article.
April 11, 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/28382862/inflammatory-bowel-disease-new-therapeutic-options-in-the-post-anti-tnf%C3%AE-era
#11
Miguel Jiménez Pérez, Raúl V Olmedo Martín, Víctor M Amo Trillo, Rocío González Gande
Inflammatory bowel diseasesare chronic bowel disorders the causes of which have not been fully elucidated,though they all sharean immunological basis. They have an important impact on both quality of life of the patient and on healthcare services. The incorporation of biological agents against tumour necrosis factor (TNF) alpha some 15 years ago represented a revolution in the management of patients with disease that did not respond to conventional treatment, enabling an overall improvement in the quality of life of many of these patients...
April 6, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28380749/passive-athermalization-of-multimode-interference-devices-for-wavelength-locking-applications
#12
Victor I Ruiz-Perez, Daniel A May-Arrioja, Jose R Guzman-Sepulveda
In this paper we demonstrate the passive, material-based athermalization of all-fiber architectures by cascading multimode interference (MMI) devices. In-line thermal compensation is achieved by including a liquid-core multimode section of variable length that allows ensuring temperature-independent operation while preserving the inherent filter-like spectral response of the MMI devices. The design of the temperature compensation unit is straightforward and its fabrication is simple. The applicability of our approach is experimentally verified by fabricating a wavelength-locked MMI laser with sensitivity of only -0...
March 6, 2017: Optics Express
https://www.readbyqxmd.com/read/28380695/adherence-to-nutrition-based-cancer-prevention-guidelines-and-breast-prostate-and-colorectal-cancer-risk-in-the-mcc-spain-case-control-study
#13
Dora Romaguera, Esther Gracia-Lavedan, Amaia Molinuevo, Jordi de Batlle, Michelle Mendez, Victor Moreno, Carmen Vidal, Adela Castelló, Beatriz Pérez-Gómez, Vicente Martín, Antonio J Molina, Verónica Dávila-Batista, Trinidad Dierssen-Sotos, Inés Gómez-Acebo, Javier Llorca, Marcela Guevara, Jesús Castilla, Carmen Urtiaga, Cristóbal Llorens-Ivorra, Guillermo Fernández-Tardón, Adonina Tardón, José Andrés Lorca, Rafael Marcos-Gragera, José María Huerta, Rocío Olmedo-Requena, José Juan Jimenez-Moleon, Jone Altzibar, Silvia de Sanjosé, Marina Pollán, Núria Aragonés, Gemma Castaño-Vinyals, Manolis Kogevinas, Pilar Amiano
Prostate, breast and colorectal cancer are the most common tumours in Spain. The aim of the present study was to evaluate the association between adherence to nutrition-based guidelines for cancer prevention and prostate, breast and colorectal cancer, in the MCC-Spain case-control study. A total of 1718 colorectal, 1343 breast and 864 prostate cancer cases and 3431 population-based controls recruited between 2007 and 2012, were included in the present study. The World Cancer Research Fund/American Institute for Cancer Research (WCRC/AICR) score based on six recommendations for cancer prevention (on body fatness, physical activity, foods and drinks that promote weight gain, plant foods, animal foods and alcoholic drinks; score range 0-6) was constructed...
April 5, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28377175/tactile-object-categories-can-be-decoded-from-the-parietal-and-lateral-occipital-cortices
#14
Raúl Hernández-Pérez, Laura V Cuaya, Eduardo Rojas-Hortelano, Azalea Reyes-Aguilar, Luis Concha, Victor de Lafuente
The visual system classifies objects into categories, and distinct populations of neurons within the temporal lobe respond preferentially to objects of a given perceptual category. We can also classify the objects we recognize with the sense of touch, but less is known about the neuronal correlates underlying this cognitive function. To address this question, we performed a multivariate pattern analysis (MVPA) of functional magnetic resonance imagining (fMRI) activity to identify the cortical areas that can be used to decode the category of objects explored with the hand...
April 2, 2017: Neuroscience
https://www.readbyqxmd.com/read/28376919/eye-movement-desensitization-and-reprocessing-therapy-versus-supportive-therapy-in-affective-relapse-prevention-in-bipolar-patients-with-a-history-of-trauma-study-protocol-for-a-randomized-controlled-trial
#15
Ana Moreno-Alcázar, Joaquim Radua, Ramon Landín-Romero, Laura Blanco, Mercè Madre, Maria Reinares, Mercè Comes, Esther Jiménez, Jose Manuel Crespo, Eduard Vieta, Victor Pérez, Patricia Novo, Marta Doñate, Romina Cortizo, Alicia Valiente-Gómez, Walter Lupo, Peter J McKenna, Edith Pomarol-Clotet, Benedikt L Amann
BACKGROUND: Up to 60% of patients with bipolar disorder (BD) have a history of traumatic events, which is associated with greater episode severity, higher risk of comorbidity and higher relapse rates. Trauma-focused treatment strategies for BD are thus necessary but studies are currently scarce. The aim of this study is to examine whether Eye Movement Desensitization and Reprocessing (EMDR) therapy focusing on adherence, insight, de-idealisation of manic symptoms, prodromal symptoms and mood stabilization can reduce episode severity and relapse rates and increase cognitive performance and functioning in patients with BD...
April 4, 2017: Trials
https://www.readbyqxmd.com/read/28375014/mapping-the-long-range-electron-transfer-route-in-ligninolytic-peroxidases
#16
Sandra Acebes, Francisco J Ruiz-Dueñas, Mario Toubes, Veronica Sáez-Jiménez, Marta Pérez-Boada, M Fátima Lucas, Angel T Martínez, Victor Guallar
Combining a computational analysis with site-directed mutagenesis, we have studied the long-range electron transfer pathway in versatile and lignin peroxidases, two enzymes of biotechnological interest that play a key role for fungal degradation of the bulky lignin molecule in plant biomass. The in silico study established two possible electron transfer routes starting at the surface tryptophan residue previously identified as responsible for oxidation of the bulky lignin polymer. Moreover, in both enzymes, a second buried tryptophan residue appears as a top electron transfer carrier, indicating the prevalence of one pathway...
April 14, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28368991/ocular-surface-parameters-predicting-patient-satisfaction-after-a-single-vectored-thermal-pulsation-procedure-for-management-of-symptomatic-meibomian-gland-dysfunction
#17
Allister Gibbons, Daniel Waren, Nilufer Yesilirmak, Kendra Davis, Felipe Valenzuela, Juan C Murillo, Victor L Perez
PURPOSE: To evaluate the ocular surface parameters that could predict patient satisfaction after single application of vectored thermal pulsation (VTP). METHODS: This is a retrospective interventional case series; it included consecutive patients who underwent bilateral VTP for management of symptomatic meibomian gland dysfunction (MGD). Patients received a full ocular surface evaluation. The outcome was patient subjective improvement during the first 3-4 months after 3 follow-up visits...
March 31, 2017: Cornea
https://www.readbyqxmd.com/read/28367087/expression-of-sterol-regulatory-element-binding-proteins-in-epicardial-adipose-tissue-in-patients-with-coronary-artery-disease-and-diabetes-mellitus-preliminary-study
#18
Luis M Pérez-Belmonte, Inmaculada Moreno-Santos, Fernando Cabrera-Bueno, Gemma Sánchez-Espín, Daniel Castellano, Miguel Such, María G Crespo-Leiro, Fernando Carrasco-Chinchilla, Luis Alonso-Pulpón, Miguel López-Garrido, Amalio Ruiz-Salas, Víctor M Becerra-Muñoz, Juan J Gómez-Doblas, Eduardo de Teresa-Galván, Manuel Jiménez-Navarro
Objectives: Sterol regulatory element-binding proteins (SREBP) genes are crucial in lipid biosynthesis and cardiovascular homeostasis. Their expression in epicardial adipose tissue (EAT) and their influence in the development of coronary artery disease (CAD) and type-2 diabetes mellitus remain to be determined. The aim of our study was to evaluate the expression of SREBP genes in EAT in patients with CAD according to diabetes status and its association with clinical and biochemical data. Methods: SREBP-1 and SREBP-2 mRNA expression levels were measured in EAT from 49 patients with CAD (26 with diabetes) and 23 controls without CAD or diabetes...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28356599/towards-personalized-medicine-in-melanoma-implementation-of-a-clinical-next-generation-sequencing-panel
#19
Blanca de Unamuno Bustos, Rosa Murria Estal, Gema Pérez Simó, Inmaculada de Juan Jimenez, Begoña Escutia Muñoz, Mercedes Rodríguez Serna, Victor Alegre de Miquel, Margarita Llavador Ros, Rosa Ballester Sánchez, Eduardo Nagore Enguídanos, Sarai Palanca Suela, Rafael Botella Estrada
Molecular diagnostics are increasingly performed routinely in the diagnosis and management of patients with melanoma due to the development of novel therapies that target specific genetic mutations. The development of next-generation sequencing (NGS) technologies has enabled to sequence multiple cancer-driving genes in a single assay, with improved sensitivity in mutation detection. The main objective of this study was the design and implementation of a melanoma-specific sequencing panel, and the identification of the spectrum of somatic mutations in a series of primary melanoma samples...
March 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28355222/transaldolase-inhibition-impairs-mitochondrial-respiration-and-induces-a-starvation-like-longevity-response-in-caenorhabditis-elegans
#20
Christopher F Bennett, Jane J Kwon, Christine Chen, Joshua Russell, Kathlyn Acosta, Nikolay Burnaevskiy, Matthew M Crane, Alessandro Bitto, Helen Vander Wende, Marissa Simko, Victor Pineda, Ryan Rossner, Brian M Wasko, Haeri Choi, Shiwen Chen, Shirley Park, Gholamali Jafari, Bryan Sands, Carissa Perez Olsen, Alexander R Mendenhall, Philip G Morgan, Matt Kaeberlein
Mitochondrial dysfunction can increase oxidative stress and extend lifespan in Caenorhabditis elegans. Homeostatic mechanisms exist to cope with disruptions to mitochondrial function that promote cellular health and organismal longevity. Previously, we determined that decreased expression of the cytosolic pentose phosphate pathway (PPP) enzyme transaldolase activates the mitochondrial unfolded protein response (UPRmt) and extends lifespan. Here we report that transaldolase (tald-1) deficiency impairs mitochondrial function in vivo, as evidenced by altered mitochondrial morphology, decreased respiration, and increased cellular H2O2 levels...
March 2017: PLoS Genetics
keyword
keyword
94769
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"