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Victor Perez

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https://www.readbyqxmd.com/read/28092256/-resection-of-intracardiac-myxoma-case-report
#1
Víctor Manuel Carmona-Delgado, Angélica María Deloya-Maldonado, María Lourdes Carranza-Bernal, Arturo Hinojosa-Pérez, Leobardo Farías-Mayene
Myxomas are the most common benign cardiac tumors, which are considered emergency surgery. The resection should not be delayed because 8-9% of affected patients may die due to intracardiac blood flow obstruction. We presente a clinical case of a 47 year old female, history of dyslipidemia. Disease starts with retrosternal oppression feeling, dyspnea on moderate exercise, dizziness, pain in joints hands. Arrhytmic heart sounds, diastolic mitral murmur II/IV, breth sounds present, no lymph. Laboratory: hemoglobin 11...
January 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28092247/-emergency-obstetric-causes-and-immediate-response-team-in-a-secondary-hospital
#2
Luis Rafael López-Ocaña, Norma Angélica Hernández-Pineda, Polita Rocío Cruz-Cruz, Manuel Ramiro-H, Víctor Octavio Pérez Del Valle-Ibarra
BACKGROUND: The aim of this work is to describe the causes of the obstetric emergency, which motivates the activation of the Immediate Response Team at a second level hospital of the Instituto Mexicano del Seguro Social, which has not an Intensive Care Unit for Adult Patients. METHODS: Retrospective observational study of the causes of obstetric emergency that occurred in the domains of Admission, Hospitalization, Labor, Delivery Room, Operating Room and Recovery of the Hospital General de Zona 53 of the IMSS, during the years 2014 and 2015...
January 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28088073/strategies-to-design-clinical-studies-to-identify-predictive-biomarkers-in-cancer-research
#3
REVIEW
Jose Luis Perez-Gracia, Miguel F Sanmamed, Ana Bosch, Ana Patiño-Garcia, Kurt A Schalper, Victor Segura, Joaquim Bellmunt, Josep Tabernero, Christopher J Sweeney, Toni K Choueiri, Miguel Martín, Juan Pablo Fusco, Maria Esperanza Rodriguez-Ruiz, Alfonso Calvo, Celia Prior, Luis Paz-Ares, Ruben Pio, Enrique Gonzalez-Billalabeitia, Alvaro Gonzalez Hernandez, David Páez, Jose María Piulats, Alfonso Gurpide, Mapi Andueza, Guillermo de Velasco, Roberto Pazo, Enrique Grande, Pilar Nicolas, Francisco Abad-Santos, Jesus Garcia-Donas, Daniel Castellano, María J Pajares, Cristina Suarez, Ramon Colomer, Luis M Montuenga, Ignacio Melero
The discovery of reliable biomarkers to predict efficacy and toxicity of anticancer drugs remains one of the key challenges in cancer research. Despite its relevance, no efficient study designs to identify promising candidate biomarkers have been established. This has led to the proliferation of a myriad of exploratory studies using dissimilar strategies, most of which fail to identify any promising targets and are seldom validated. The lack of a proper methodology also determines that many anti-cancer drugs are developed below their potential, due to failure to identify predictive biomarkers...
December 30, 2016: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28062831/glioblastoma-on-a-microfluidic-chip-generating-pseudopalisades-and-enhancing-aggressiveness-through-blood-vessel-obstruction-events
#4
Jose M Ayuso, Rosa Monge, Alicia Martínez-González, María Virumbrales-Muñoz, Guillermo A Llamazares, Javier Berganzo, Aurelio Hernández-Laín, Jorge Santolaria, Manuel Doblaré, Christopher Hubert, Jeremy N Rich, Pilar Sánchez-Gómez, Víctor M Pérez-García, Ignacio Ochoa, Luis J Fernández
BACKGROUND: Glioblastoma (GBM) is one of the most lethal tumor types. Hypercellular regions, named pseudopalisades, are characteristic in these tumors and have been hypothesized to be waves of migrating glioblastoma cells. These "waves" of cells are thought to be induced by oxygen and nutrient depletion caused by tumor-induced blood vessel occlusion. Although the universal presence of these structures in GBM tumors suggests that they may play an instrumental role in GBM's spread and invasion, the recreation of these structures in vitro has remained challenging...
January 6, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28039838/fibroblast-growth-factor-21-and-its-novel-association-with-oxidative-stress
#5
REVIEW
Miguel Ángel Gómez-Sámano, Mariana Grajales-Gómez, Julia María Zuarth-Vázquez, Ma Fernanda Navarro-Flores, Mayela Martínez-Saavedra, Óscar Alfredo Juárez-León, Mariana G Morales-García, Víctor Manuel Enríquez-Estrada, Francisco J Gómez-Pérez, Daniel Cuevas-Ramos
Fibroblast growth factor 21 (FGF21) is an endocrine-member of the FGF family. It is synthesized mainly in the liver, but it is also expressed in adipose tissue, skeletal muscle, and many other organs. It has a key role in glucose and lipid metabolism, as well as in energy balance. FGF21 concentration in plasma is increased in patients with obesity, insulin resistance, and metabolic syndrome. Recent findings suggest that such increment protects tissue from an increased oxidative stress environment. Different types of physical stress, such as strenuous exercising, lactation, diabetic nephropathy, cardiovascular disease, and critical illnesses, also increase FGF21 circulating concentration...
December 22, 2016: Redox Biology
https://www.readbyqxmd.com/read/28025484/cross-view-gait-recognition-using-joint-direct-linear-discriminant-analysis
#6
Jose Portillo-Portillo, Roberto Leyva, Victor Sanchez, Gabriel Sanchez-Perez, Hector Perez-Meana, Jesus Olivares-Mercado, Karina Toscano-Medina, Mariko Nakano-Miyatake
This paper proposes a view-invariant gait recognition framework that employs a unique view invariant model that profits from the dimensionality reduction provided by Direct Linear Discriminant Analysis (DLDA). The framework, which employs gait energy images (GEIs), creates a single joint model that accurately classifies GEIs captured at different angles. Moreover, the proposed framework also helps to reduce the under-sampling problem (USP) that usually appears when the number of training samples is much smaller than the dimension of the feature space...
December 22, 2016: Sensors
https://www.readbyqxmd.com/read/28017790/the-cb1-receptor-is-required-for-the-establishment-of-the-hyperlocomotor-phenotype-in-developmentally-induced-hypothyroidism-in-mice
#7
Elena Giné, Victor Echeverry-Alzate, Jose Antonio Lopez-Moreno, Fernando Rodriguez de Fonseca, Ana Perez-Castillo, Angel Santos
Alterations in motor functions are well-characterized features observed in humans and experimental animals with thyroid hormone dysfunctions during development. We have previously suggested the implication of the endocannabinoid system in the hyperlocomotor phenotype observed in developmentally induced hypothyroidism in rats. In this work we have further analyzed the implication of endocannabinoids in the effect of hypothyroidism on locomotor activity. To this end, we evaluated the locomotor activity in adult mice lacking the cannabinoid receptor type 1 (CB1R(-/-)) and in their wild type littermates (CB1R(+/+)), whose hypothyroidism was induced in day 12 of gestation and maintained during the experimental period...
December 23, 2016: Neuropharmacology
https://www.readbyqxmd.com/read/27995169/complementary-pharmacological-and-toxicological-characterization-data-on-the-pharmacological-profile-of-n-2-6-dichlorophenyl-2-4-methyl-1-piperidinyl-acetamide
#8
Myrna Déciga-Campos, Gabriel Navarrete-Vázquez, Francisco Javier López-Muñoz, Tadeusz Librowski, Amanda Sánchez-Recillas, Victor Yañez-Pérez, Rolffy Ortiz-Andrade
This text presents complementary data corresponding to pharmacological and toxicological characterization of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide (LIA) compound. These data support our research article entitled "Pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide, a novel analog of lidocaine" Déciga-Campos M., Navarrete-Vázquez G., López-Muñoz F.J., Librowski T., Sánchez-Recillas A., Yañez-Pérez V., Ortiz-Andrade R. (2016) [1]. Toxicity was predicted through the ACD/ToxSuite software and evaluated in vivo using brine shrimp larvae (Artemia salina L...
September 2016: Data in Brief
https://www.readbyqxmd.com/read/27981471/metabolic-tumor-burden-assessed-by-dual-time-point-18-f-fdg-pet-ct-in-locally-advanced-breast-cancer-relation-with-tumor-biology
#9
Ana María Garcia-Vicente, Julián Pérez-Beteta, Víctor Manuel Pérez-García, David Molina, German Andrés Jiménez-Londoño, Angel Soriano-Castrejón, Alicia Martínez-González
PURPOSE: The aim of the study was to investigate the influence of dual time point 2-deoxy-2-[(18)F]fluoro-D-glucose ([(18)F]FDG) positron emission tomography/x-ray computed tomography (PET/CT) on the standard uptake value (SUV) and volume-based metabolic variables of breast lesions and their relation with biological characteristics and molecular phenotypes. PROCEDURES: Retrospective analysis including 67 patients with locally advanced breast cancer (LABC). All patients underwent a dual time point [(18)F]FDG PET/CT, 1 h (PET-1) and 3 h (PET-2) after [(18)F]FDG administration...
December 15, 2016: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/27959928/an-efficient-microarray-based-genotyping-platform-for-the-identification-of-drug-resistance-mutations-in-majority-and-minority-subpopulations-of-hiv-1-quasispecies
#10
Verónica Martín, Celia Perales, María Fernández-Algar, Helena G Dos Santos, Patricia Garrido, María Pernas, Víctor Parro, Miguel Moreno, Javier García-Pérez, José Alcamí, José Luis Torán, David Abia, Esteban Domingo, Carlos Briones
The response of human immunodeficiency virus type 1 (HIV-1) quasispecies to antiretroviral therapy is influenced by the ensemble of mutants that composes the evolving population. Low-abundance subpopulations within HIV-1 quasispecies may determine the viral response to the administered drug combinations. However, routine sequencing assays available to clinical laboratories do not recognize HIV-1 minority variants representing less than 25% of the population. Although several alternative and more sensitive genotyping techniques have been developed, including next-generation sequencing (NGS) methods, they are usually very time consuming, expensive and require highly trained personnel, thus becoming unrealistic approaches in daily clinical practice...
2016: PloS One
https://www.readbyqxmd.com/read/27958608/efficient-preparation-of-carbamates-by-rh-catalysed-oxidative-carbonylation-unveiling-the-role-of-the-oxidant
#11
Amaia Iturmendi, Manuel Iglesias, Julen Munárriz, Victor Polo, Jesús J Pérez-Torrente, Luis A Oro
The synthesis of a wide variety of carbamates from amines, alcohols and carbon monoxide has been achieved by means of a Rh-catalysed oxidative carbonylation reaction that uses Oxone as a stoichiometric oxidant. In-depth studies on the reaction mechanism shed light on the intimate role of Oxone in the catalytic cycle.
December 22, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27928075/detecting-mutations-in-the-mycobacterium-tuberculosis-pyrazinamidase-gene-pnca-to-improve-infection-control-and-decrease-drug-resistance-rates-in-human-immunodeficiency-virus-coinfection
#12
Matthew Z Dudley, Patricia Sheen, Robert H Gilman, Eduardo Ticona, Jon S Friedland, Daniela E Kirwan, Luz Caviedes, Richard Rodriguez, Lilia Z Cabrera, Jorge Coronel, Louis Grandjean, David A J Moore, Carlton A Evans, Luz Huaroto, Víctor Chávez-Pérez, Mirko Zimic
Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)-positive patients, as these patients are at heightened risk of developing TB. Pyrazinamide (PZA) is a potent drug that effectively sterilizes persistent Mycobacterium tuberculosis bacilli. However, PZA resistance associated with mutations in the nicotinamidase/pyrazinamidase coding gene, pncA, is increasing. A total of 794 patient isolates obtained from four sites in Lima, Peru, underwent spoligotyping and drug resistance testing...
December 7, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27907177/correction-predicting-response-trajectories-during-cognitive-behavioural-therapy-for-panic-disorder-no-association-with-the-bdnf-gene-or-childhood-maltreatment
#13
Martí Santacana, Bárbara Arias, Marina Mitjans, Albert Bonillo, María Montoro, Sílvia Rosado, Roser Guillamat, Vicenç Vallès, Víctor Pérez, Carlos G Forero, Miquel A Fullana
[This corrects the article DOI: 10.1371/journal.pone.0158224.].
2016: PloS One
https://www.readbyqxmd.com/read/27905915/erratum-to-validation-of-the-spanish-version-of-the-borderline-symptom-list-short-form-bsl-23
#14
Joaquim Soler, Daniel Vega, Albert Feliu-Soler, Joan Trujols, Ángel Soto, Matilde Elices, Cristina Ortiz, Víctor Pérez, Martin Bohus, Juan Carlos Pascual
No abstract text is available yet for this article.
December 1, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27902799/genomic-prediction-of-genotype-%C3%A3-environment-interaction-kernel-regression-models
#15
Jaime Cuevas, José Crossa, Víctor Soberanis, Sergio Pérez-Elizalde, Paulino Pérez-Rodríguez, Gustavo de Los Campos, O A Montesinos-López, Juan Burgueño
In genomic selection (GS), genotype × environment interaction (G × E) can be modeled by a marker × environment interaction (M × E). The G × E may be modeled through a linear kernel or a nonlinear (Gaussian) kernel. In this study, we propose using two nonlinear Gaussian kernels: the reproducing kernel Hilbert space with kernel averaging (RKHS KA) and the Gaussian kernel with the bandwidth estimated through an empirical Bayesian method (RKHS EB). We performed single-environment analyses and extended to account for G × E interaction (GBLUP-G × E, RKHS KA-G × E and RKHS EB-G × E) in wheat ( L...
November 2016: Plant Genome
https://www.readbyqxmd.com/read/27893092/global-patterns-in-health-burden-of-uncorrected-refractive-error
#16
Lixia Lou, Chunlei Yao, Yanhua Jin, Victor Perez, Juan Ye
Purpose: To evaluate the global patterns in health burden of uncorrected refractive error (URE) by year, age and sex, region, and socioeconomic status, using disability-adjusted life years (DALYs). Methods: Global, regional, or national DALY numbers, crude DALY rates, and age-standardized DALY rates caused by URE, by year, or age and sex, were obtained from the Global Burden of Disease Study 2013. Human development index (HDI) in 2013 as a national socioeconomic indicator was obtained from the Human Development Report...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27886269/in-silico-clustering-of-salmonella-global-gene-expression-data-reveals-novel-genes-co-regulated-with-the-spi-1-virulence-genes-through-hild
#17
Irma Martínez-Flores, Deyanira Pérez-Morales, Mishael Sánchez-Pérez, Claudia C Paredes, Julio Collado-Vides, Heladia Salgado, Víctor H Bustamante
A wide variety of Salmonella enterica serovars cause intestinal and systemic infections to humans and animals. Salmonella Patogenicity Island 1 (SPI-1) is a chromosomal region containing 39 genes that have crucial virulence roles. The AraC-like transcriptional regulator HilD, encoded in SPI-1, positively controls the expression of the SPI-1 genes, as well as of several other virulence genes located outside SPI-1. In this study, we applied a clustering method to the global gene expression data of S. enterica serovar Typhimurium from the COLOMBOS database; thus genes that show an expression pattern similar to that of SPI-1 genes were selected...
November 25, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27885555/meat-intake-cooking-methods-and-doneness-and-risk-of-colorectal-tumours-in-the-spanish-multicase-control-study-mcc-spain
#18
Jordi de Batlle, Esther Gracia-Lavedan, Dora Romaguera, Michelle Mendez, Gemma Castaño-Vinyals, Vicente Martín, Núria Aragonés, Inés Gómez-Acebo, Rocío Olmedo-Requena, José Juan Jimenez-Moleon, Marcela Guevara, Mikel Azpiri, Cristóbal Llorens-Ivorra, Guillermo Fernandez-Tardon, Jose Andrés Lorca, José María Huerta, Victor Moreno, Elena Boldo, Beatriz Pérez-Gómez, Jesús Castilla, Tania Fernández-Villa, Juan Pablo Barrio, Montserrat Andreu, Antoni Castells, Trinidad Dierssen, Jone M Altzibar, Manolis Kogevinas, Marina Pollán, Pilar Amiano
PURPOSE: Although there is convincing evidence that red and processed meat intake increases the risk of colorectal cancer (CRC), the potential role of meat cooking practices has not been established yet and could partly explain the current heterogeneity of results among studies. Therefore, we aimed to investigate the association between meat consumption and cooking practices and the risk of CRC in a population-based case-control study. METHODS: A total of 1671 CRC cases and 3095 controls recruited in Spain between September 2008 and December 2013 completing a food frequency questionnaire with a meat-specific module were included in the analyses...
November 24, 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/27877139/corrigendum-regularization-techniques-for-ecg-imaging-during-atrial-fibrillation-a-computational-study
#19
Carlos Figuera, Víctor Suárez-Gutiérrez, Ismael Hernández-Romero, Miguel Rodrigo, Alejandro Liberos, Felipe Atienza, María S Guillem, Óscar Barquero-Pérez, Andreu M Climent, Felipe Alonso-Atienza
[This corrects the article on p. 466 in vol. 7, PMID: 27790158.].
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27876836/nf-kappa%C3%AE-inducing-kinase-regulates-stem-cell-phenotype-in-breast-cancer
#20
Karla Vazquez-Santillan, Jorge Melendez-Zajgla, Luis Enrique Jimenez-Hernandez, Javier Gaytan-Cervantes, Laura Muñoz-Galindo, Patricia Piña-Sanchez, Gustavo Martinez-Ruiz, Javier Torres, Patricia Garcia-Lopez, Carolina Gonzalez-Torres, Victor Ruiz, Federico Avila-Moreno, Marco Velasco-Velazquez, Mayra Perez-Tapia, Vilma Maldonado
Breast cancer stem cells (BCSCs) overexpress components of the Nuclear factor-kappa B (NF-κB) signaling cascade and consequently display high NF-κB activity levels. Breast cancer cell lines with high proportion of CSCs exhibit high NF-κB-inducing kinase (NIK) expression. The role of NIK in the phenotype of cancer stem cell regulation is poorly understood. Expression of NIK was analyzed by quantitative RT-PCR in BCSCs. NIK levels were manipulated through transfection of specific shRNAs or an expression vector...
November 23, 2016: Scientific Reports
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