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Vitamin B 6

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https://www.readbyqxmd.com/read/29231753/rates-of-insufficiency-and-deficiency-of-vitamin-d-levels-in-elite-professional-male-and-female-skiers-a-chronobiologic-approach
#1
Jacopo Antonino Vitale, Giovanni Lombardi, Luca Cavaleri, Rosa Graziani, Herbert Schoenhuber, Antonio La Torre, Giuseppe Banfi
Vitamin D is essential for the maintenance and promotion of musculoskeletal health, for the functioning of the immune, cardiovascular and reproductive systems, and its main action is to keep calcium and phosphate plasmatic physiological concentrations at intestinal, renal and bony level. Vitamin D affects several parameters related to physical performance too and a particularly high percentage of vitamin D insufficiency and deficiency in professional athletes has been observed. Several variables are able to impair the synthesis of 25(OH)D in athletes, specifically both genetic and environmental factors, but the most probable explanation for the deficient/insufficient vitamin D levels is the insufficient ultraviolet B light (UVB) exposure during winter...
December 12, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29224648/effect-of-high-dose-oral-multivitamins-and-minerals-in-participants-not-treated-with-statins-in-the-randomized-trial-to-assess-chelation-therapy-tact
#2
Omar M Issa, Rhonda Roberts, Daniel B Mark, Robin Boineau, Christine Goertz, Yves Rosenberg, Eldrin F Lewis, Erminia Guarneri, Jeanne Drisko, Allan Magaziner, Kerry L Lee, Gervasio A Lamas
IMPORTANCE: In a prespecified subgroup analysis of participants not on statin therapy at baseline in the TACT, a high-dose complex oral multivitamins and multimineral regimen was found to have a large unexpected benefit compared with placebo. The regimen tested was substantially different from any vitamin regimen tested in prior clinical trials. OBJECTIVE: To explore these results, we performed detailed additional analyses of participants not on statins at enrollment in TACT...
January 2018: American Heart Journal
https://www.readbyqxmd.com/read/29222896/serum-vitamin-b-12-in-children-presenting-with-vasovagal-syncope
#3
Ayhan Pektas, Resit Koken, Halit Bugra Koca
BACKGROUND AND OBJECTIVES: The present study aims to determine the serum vitamin B-12 in children presenting with vasovagal syncope. METHODS AND STUDY DESIGN: This is a prospective review of 160 children presenting with vasovagal syncope. Subgroup analysis was done based on the results of head up tilt test. RESULTS: Head up tilt test gave positive results in 80 children and yielded negative results in the remaining 80 children. The tilt test positive children had significantly lower thyroid stimulating hormone concentrations (p=0...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29222885/chronic-low-grade-inflammation-measured-by-dietary-inflammatory-index-and-its-association-with-obesity-among-school-teachers-in-yangon-myanmar
#4
Khin Mittar Moe San, Umi Fahmida, Fiastuti Wijaksono, Htin Lin, Ko Ko Zaw, Min Kyaw Htet
BACKGROUND AND OBJECTIVES: This study was aimed to investigate the association between obesity and chronic low grade inflammation (CLGI) measured by Dietary Inflammatory Index (DII) as a proxy indicator of CLGI among obese and non-obese teachers. METHODS AND STUDY DESIGN: We conducted a cross sectional study among 128 non-obese (BMI <25) and 116 obese (BMI >=25) female teachers aged 25-60 years from six urban schools in Yangon, Myanmar between January and March 2015...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29220424/genetically-deprived-vitamin-d-exposure-predisposes-to-atrial-fibrillation
#5
Yap-Hang Chan, Kai-Hang Yiu, Jo Jo Hai, Pak-Hei Chan, Tai-Hing Lam, Ben J Cowling, Pak-Chung Sham, Chu-Pak Lau, Karen Siu-Ling Lam, Chung-Wah Siu, Hung-Fat Tse
Aims: Low vitamin D level is associated with atrial fibrillation (AF) and may be implicated in its pathogenesis. Methods and results: We studied single nucleotide polymorphisms (SNPs) of vitamin D mechanistic pathways and serum 25-hydroxyvitamin D [25(OH)D] levels in an age- and gender-matched case-control study (controls without AF: mean age 68.6 ± 8.7 years, female 25%; n = 1019; with AF: mean age 69.7 ± 9.5 years, female 30%; n = 156) recruited from a Chinese clinical cohort of patients with stable coronary artery disease...
December 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29211007/contribution-of-dietary-supplements-to-nutritional-adequacy-in-various-adult-age-groups
#6
Jeffrey B Blumberg, Balz Frei, Victor L Fulgoni, Connie M Weaver, Steven H Zeisel
Many Americans have inadequate intakes of several nutrients. The Dietary Guidelines for Americans 2015-2020 specifically identified vitamins A, C, D and E, calcium, magnesium, iron, potassium, choline and fiber as "underconsumed nutrients". Based on nationally representative data in 10,698 adults from National Health and Nutrition Examination Surveys (NHANES), 2009-2012, assessments were made of age-group differences in the impact of dietary supplements on nutrient intake and inadequacies. Compared to food alone, use of any dietary supplement plus food was associated with significantly (p < 0...
December 6, 2017: Nutrients
https://www.readbyqxmd.com/read/29209689/could-a-vitamin-d-deficiency-cause-a-combined-long-term-fev1-and-bone-mineral-density-deterioration-in-female-asthmatics
#7
B Sposato, M Scalese, L Petruzzelli, E Baldini, N Nikiforakis, M Tosti Balducci
OBJECTIVES: We already know that asthma is associated to osteoporosis/osteopenia and characterized by an accelerated lung function decline. Our study aimed at assessing whether lung function decline and bone mineral density (BMD) deterioration in time were associated in a group of female long-standing asthmatics. We also tried to understand whether these two aspects were related to ICS treatment and vitamin D levels. METHODS: 35 female asthmatics were retrospectively analysed...
November 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29207799/change-in-bone-mineral-density-and-role-of-vitamin-d-and-calcium-supplementation-during-treatment-of-first-episode-nephrotic-syndrome
#8
Virendra Kumar Yadav, Shobha Sharma, Pradeep Kumar Debata, Seema Patel, Bhaskar C Kabi, Kailash Chandra Aggrawal
Introduction: Nephrotic Syndrome (NS) is one of the common illnesses in childhood. Oral glucocorticoids are mainstay of treatment, which are known to cause various short term and long term adverse effects including osteoporosis. Children with first episode and infrequent relapsing NS are not prescribed Calcium (Ca) and Vitamin D (VitD) supplements routinely. Aim: To observe change in Bone Mineral Density (BMD) in children during first episode of NS and role of VitD and Ca supplementation during the treatment of first episode of NS...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29206972/nutritional-deficiencies-and-clinical-correlates-in-first-episode-psychosis-a-systematic-review-and-meta-analysis
#9
Joseph Firth, Rebekah Carney, Brendon Stubbs, Scott B Teasdale, Davy Vancampfort, Philip B Ward, Michael Berk, Jerome Sarris
Objective: Diet is increasingly recognized as a potentially modifiable factor influencing the onset and outcomes of psychiatric disorders. Whereas, previous research has shown long-term schizophrenia is associated with various nutritional deficiencies, this meta-analysis aimed to determine the prevalence and extent of nutritional deficits in first-episode psychosis (FEP). Method: A search of electronic databases conducted in July 2017 identified 28 eligible studies, examining blood levels of 6 vitamins and 10 minerals across 2612 individuals: 1221 individuals with FEP and 1391 control subjects...
November 30, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29200604/genetic-impact-of-rht-dwarfing-genes-on-grain-micronutrients-concentration-in-wheat
#10
Govindan Velu, Ravi P Singh, Julio Huerta, Carlos Guzmán
Wheat is a major staple food crop providing about 20% of dietary energy and proteins, and food products made of whole grain wheat are a major source of micronutrients like Zinc (Zn), Iron (Fe), Manganese (Mn), Magnesium (Mg), Vitamin B and E. Wheat provides about 40% intake of essential micronutrients by humans in the developing countries relying on wheat based diets. Varieties with genetically enhanced levels of grain micronutrient concentrations can provide a cost-effective and sustainable option to resource poor wheat consumers...
December 2017: Field Crops Research
https://www.readbyqxmd.com/read/29190137/high-risk-gastric-pathology-and-prevalent-autoimmune-diseases-in-patients-with-pernicious-anemia
#11
Jing W Hughes, Brian D Muegge, Garry S Tobin, Marina Litvin, Lulu Sun, Jose B Saenz, C Prakash Gyawali, Janet B McGill
OBJECTIVE: Pernicious anemia (PA) develops from atrophic gastritis due to autoimmune destruction of parietal cells and results in achlorhydria, vitamin B12 and iron deficiencies, anemia, neurologic deficits, and premalignant and malignant stomach lesions. We report the presentation, diagnosis and gastric complications of PA in patients from an endocrinology practice. METHODS: Thirty-four patients (31 female, 3 male) with PA who underwent esophagogastroduodenoscopy (EGD) or gastrectomy were identified...
November 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29188877/vitamin-d-status-and-elevated-red-cell-distribution-width-in-community-dwelling-adults-results-from-the-national-health-and-nutrition-examination-survey-2001-2006
#12
T M N Otero, D J Monlezun, K B Christopher, C A Camargo, S A Quraishi
OBJECTIVES: Elevated red cell distribution width (RDW) is associated with morbidity and mortality in community-dwelling individuals. Although RDW is traditionally used to diagnose anemia, it may also be a marker of systemic inflammation. Since vitamin D is a potent modulator of inflammatory cytokines our goal was to investigate whether 25-hydroxyvitamin D levels (25OHD) are associated with RDW in non-hospitalized adults. DESIGN: To investigate this association, we conducted a cross-sectional study...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29188293/variation-of-thyroidectomy-specific-outcomes-among-hospitals-and-their-association-with-risk-adjustment-and-hospital-performance
#13
Jason B Liu, Julie A Sosa, Raymon H Grogan, Yaoming Liu, Mark E Cohen, Clifford Y Ko, Bruce L Hall
Importance: Current surgical quality metrics might be insufficient to fully judge the quality of certain operations because they are not procedure specific. Hypocalcemia, recurrent laryngeal nerve (RLN) injury, and hematoma are considered to be the most relevant outcomes to measure after thyroidectomy. Whether these outcomes can be used as hospital quality metrics is unknown. Objectives: To evaluate whether thyroidectomy-specific outcomes vary among hospitals, whether the addition of thyroidectomy-specific variables affects risk adjustment, and whether differences in hospital performance are associated with thyroidectomy-specific care processes...
November 29, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29187783/the-effect-of-micronutrient-supplementation-on-active-tb-incidence-early-in-hiv-infection-in-botswana
#14
Adriana Campa, Marianna K Baum, Hermann Bussmann, Sabrina Sales Martinez, Mansour Farahani, Erik van Widenfelt, Sikhulile Moyo, Joseph Makhema, Max Essex, Richard Marlink
Background: Coinfection with active tuberculosis (TB) is one of the leading causes of death in people living with HIV (PLWH) in Africa. This investigation explores the role of micronutrient supplementation in preventing active TB in PLWH. Methods: A randomized trial of nutritional supplementation was conducted among antiretroviral- naïve (without previous antiretroviral treatment [ART]) HIV-infected people in Botswana between 2004 and 2009. The study had a factorial design with four arms: the selenium (Se) alone arm, the multivitamins (MVT) alone arm that contained vitamin B complex and vitamins C and E, the combined Se+MVT group and the placebo group...
2017: Nutrition and Dietary Supplements
https://www.readbyqxmd.com/read/29187089/pyridoxine-deficiency-after-solid-organ-transplant
#15
Summer Van Arsdale, Sarah E Yost, Chiu-Hsieh Hsu, Mary Meer, Shari Schoentag, Shahid Habib
OBJECTIVE: Pyridoxine is 1 of 8 B vitamins that assist in a variety of essential functions including immune functions. The purpose of this study was to assess the risk factors associated with low pyridoxine levels in solid organ transplantation recipients. DESIGN: The study cohort was divided into 2 groups: (a) patients with normal pyridoxine levels or (b) patients with low pyridoxine levels. Dietary evaluation and clinical characteristics of all patients, rejection episodes, and immunosuppression were collected...
September 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29186865/role-of-vitamin-d-in-maintaining-renal-epithelial-barrier-function-in-uremic-conditions
#16
Milos Mihajlovic, Michele Fedecostante, Miriam J Oost, Sonja K P Steenhuis, Eef G W M Lentjes, Inge Maitimu-Smeele, Manoe J Janssen, Luuk B Hilbrands, Rosalinde Masereeuw
As current kidney replacement therapies are not efficient enough for end-stage renal disease (ESRD) treatment, a bioartificial kidney (BAK) device, based on conditionally immortalized human proximal tubule epithelial cells (ciPTEC), could represent an attractive solution. The active transport activity of such a system was recently demonstrated. In addition, endocrine functions of the cells, such as vitamin D activation, are relevant. The organic anion transporter 1 (OAT-1) overexpressing ciPTEC line presented 1α-hydroxylase (CYP27B1), 24-hydroxylase (CYP24A1) and vitamin D receptor (VDR), responsible for vitamin D activation, degradation and function, respectively...
November 26, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29184373/occurrence-treatment-protocols-and-outcomes-of-colic-in-horses-within-nairobi-county-kenya
#17
Anderson Gitari, James Nguhiu, Vijay Varma, Eddy Mogoa
Aim: The aim of this study was to determine the treatments and their outcomes in horses with colic in Nairobi County, Kenya. Materials and Methods: This is a retrospective study to determine the occurrence, treatments, pain management, and outcomes of colic in horses in Nairobi County. Association between pain management protocols and the outcomes of colic with regard to recovery or death was also determined. Data collected from four equine practitioners were organized manually and given numerical codes as appropriate to facilitate entry into the computer...
October 2017: Veterinary World
https://www.readbyqxmd.com/read/29176978/requirement-of-gamma-carboxyglutamic-acid-modification-and-phosphatidylserine-binding-for-the-activation-of-tyro3-axl-and-mertk-receptors-by-growth-arrest-specific-6
#18
Ke Geng, Sushil Kumar, Stanley G Kimani, Vladyslav Kholodovych, Canan Kasikara, Kensaku Mizuno, Oleta Sandiford, Pranela Rameshwar, Sergei V Kotenko, Raymond B Birge
The Tyro3, Axl, and Mertk (TAM) receptors are homologous type I receptor tyrosine kinases that have critical functions in the clearance of apoptotic cells in multicellular organisms. TAMs are activated by their endogenous ligands, growth arrest-specific 6 (Gas6), and protein S (Pros1), that function as bridging molecules between externalized phosphatidylserine (PS) on apoptotic cells and the TAM ectodomains. However, the molecular mechanisms by which Gas6/Pros1 promote TAM activation remains elusive. Using TAM/IFNγR1 reporter cell lines to monitor functional TAM activity, we found that Gas6 activity was exquisitely dependent on vitamin K-mediated γ-carboxylation, whereby replacing vitamin K with anticoagulant warfarin, or by substituting glutamic acid residues involved in PS binding, completely abrogated Gas6 activity as a TAM ligand...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29176817/individual-and-community-factors-contributing-to-anemia-among-women-in-rural-baja-california-mexico
#19
Molly A Moor, Miguel A Fraga, Richard S Garfein, Hooman H Rashidi, John Alcaraz, Donna Kritz-Silverstein, John P Elder, Stephanie K Brodine
INTRODUCTION: Anemia is a public health concern among women in rural Baja California, Mexico. The purpose of this study was to identify the individual and community factors contributing to the disproportionately high prevalence of anemia among women in this region. METHODS: A cross-sectional study of 118 women (15-49 years) was performed in a rural colonia (small settlement) in Baja California, Mexico in 2012. Participants completed a survey comprised of demographic, socioeconomic, health, and dietary questions and provided a capillary blood sample...
2017: PloS One
https://www.readbyqxmd.com/read/29175667/vitamin-k1-inversely-correlates-with-glycemia-and-insulin-resistance-in-patients-with-type-2-diabetes-t2d-and-positively-regulates-sirt1-ampk-pathway-of-glucose-metabolism-in-liver-of-t2d-mice-and-hepatocytes-cultured-in-high-glucose
#20
Anjum Dihingia, Dibyajyoti Ozah, Shatadal Ghosh, Abhijit Sarkar, Pranab Kumar Baruah, Jatin Kalita, Parames C Sil, Prasenjit Manna
There is no previous study in the literature that has examined the relationship between circulating vitamin K1 (VK1) with glycemic status in type 2 diabetes (T2D). Moreover, scientific explanation for the beneficial role of VK1 supplementation in lowering glycemia in diabetes is yet to be determined. This study for the first time demonstrated that circulating VK1 was significantly lower in T2D patients compared to age-matched control subjects, and VK1 levels in T2D were significantly and inversely associated with fasting glucose and insulin resistance [homeostatic model assessment of insulin resistance (HOMA-IR)], which suggest that boosting plasma VK1 may reduce the fasting glucose and insulin resistance in T2D patients...
October 12, 2017: Journal of Nutritional Biochemistry
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