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Vitamin B 6

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https://www.readbyqxmd.com/read/29034851/nitrosopumilus-maritimus-gen-nov-sp-nov-nitrosopumilus-cobalaminigenes-sp-nov-nitrosopumilus-oxyclinae-sp-nov-and-nitrosopumilus-ureiphilus-sp-nov-four-marine-ammonia-oxidizing-archaea-of-the-phylum-thaumarchaeota
#1
Wei Qin, Katherine R Heal, Rasika Ramdasi, Julia N Kobelt, Willm Martens-Habbena, Anthony D Bertagnolli, Shady A Amin, Christopher B Walker, Hidetoshi Urakawa, Martin Könneke, Allan H Devol, James W Moffett, E Virginia Armbrust, Grant J Jensen, Anitra E Ingalls, David A Stahl
Four mesophilic, neutrophilic, and aerobic marine ammonia-oxidizing archaea, designated strains SCM1(T), HCA1(T), HCE1(T) and PS0(T), were isolated from a tropical marine fish tank, dimly lit deep coastal waters, the lower euphotic zone of coastal waters, and near-surface sediment in the Puget Sound estuary, respectively. Cells are straight or slightly curved small rods, 0.15-0.26 µm in diameter and 0.50-1.59 µm in length. Motility was not observed, although strain PS0(T) possesses genes associated with archaeal flagella and chemotaxis, suggesting it may be motile under some conditions...
October 16, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29032627/complementary-feeding-practices-for-infants-and-young-children-in-south-asia-a-review-of-evidence-for-action-post-2015
#2
Víctor M Aguayo
Some 37% (~64 million) South Asian children under 5 years are stunted. Most stunting occurs during the complementary feeding period (6-23 months). Our objective was to (a) characterize complementary feeding practices in South Asia and (b) review the effectiveness of information, education, and counselling (IEC) interventions aiming to improve complementary feeding in South Asia. We conducted a comprehensive review of (a) the latest nationally representative survey data and (b) peer-reviewed interventions (January 1990 to December 2015) that used IEC as the main strategy to improve complementary feeding...
October 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29027817/oral-supplementation-of-parturient-mothers-with-vitamin-d-and-its-effect-on-25ohd-status-of-exclusively-breastfed-infants-at-6-months-of-age-a-double-blind-randomized-placebo-controlled-trial
#3
Prasanna Naik, M M A Faridi, Prerna Batra, S V Madhu
BACKGROUND: Exclusively breastfed infants are at increased risk of vitamin D deficiency and many lactating mothers have been found deficient in 25OHD stores. OBJECTIVE: To compare serum vitamin D levels in exclusively breastfed infants at 6 months of age with or without oral supplementation of 600,000 IU of vitamin D3 to mothers in early postpartum period. METHODS: Exclusively breastfeeding term parturient mothers were randomized 24-48 hours following delivery to receive either 600,000 IU of vitamin D3 (Cholecalciferol) over 10 days in a dose of 60,000 IU/day or placebo...
October 13, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29026390/renal-histoarchitectural-changes-in-nevirapine-therapy-possible-role-of-kolaviron-and-vitamin-c-in-an-experimental-animal-model
#4
Ugochukwu Offor, Sunday Adelaja Ajayi, Isaac Ayoola Jegede, Salem Kharwa, Edwin Coleridge Naidu, Onyemaechi Okpara Azu
BACKGROUND: There is paucity of literature regarding the nephrotoxicity of antiretroviral drugs and its interaction with plant-based adjuvants. This study investigates the attenuating effect of kolaviron in nevirapine-therapy on the histological structure of the kidneys of adult male Sprague-Dawley rats. OBJECTIVE: To determine the attenuating influence of anti-oxidant status of kolaviron on the kidneys of experimental animals following nevirapine administration...
March 2017: African Health Sciences
https://www.readbyqxmd.com/read/29020329/vitamin-d3-supplementation-increases-spine-bone-mineral-density-in-adolescents-and-young-adults-with-hiv-infection-being-treated-with-tenofovir-disoproxil-fumarate-a-randomized-placebo-controlled-trial
#5
Peter L Havens, Charles B Stephensen, Marta D Van Loan, Gertrud U Schuster, Leslie R Woodhouse, Patricia M Flynn, Catherine M Gordon, Cynthia G Pan, Brandy Rutledge, D Robert Harris, Georgine Price, Alyne Baker, William A Meyer, Craig M Wilson, Rohan Hazra, Bill G Kapogiannis, Kathleen Mulligan
Background: Tenofovir disoproxil fumarate (TDF) decreases bone mineral density (BMD). We hypothesized vitamin D3 (VITD3) would increase BMD in youth receiving TDF. Methods: Randomized double-blind placebo-controlled trial of directly observed VITD3 vs. placebo every 4 weeks for 48 weeks in youth ages 16-24 years with HIV, viral load <200 copies/mL, taking TDF-containing combination antiretroviral therapy (TDF-cART) for ≥180 days. Participants (N=214) received a daily multivitamin containing VITD3 400 IU and calcium 162 mg, plus monthly randomized VITD3 50,000 IU (N=109) or placebo (N=105)...
August 21, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28993847/vitamin%C3%A2-d-deficiency-and-functional-response-to-crt-in%C3%A2-heart-failure-patients
#6
A Separham, L Pourafkari, B Kazemi, Y Haghizadeh, F Akbarzadeh, M Toufan, H Sate, N D Nader
BACKGROUND: Vitamin D deficiency has been associated with a poor outcome in patients with heart failure (HF). We examined the role of vitamin D in the response of HF patients to cardiac resynchronization therapy (CRT). METHODS: The study comprised 50 patients (30 men and 20 women) with HF undergoing CRT implantation who were prospectively enrolled. Response to CRT was defined as a combination of ≥15% reduction in left ventricular end-systolic volume (LVESV) and ≥10% improvement in the 6‑Minute Walk Test within 6 months...
October 9, 2017: Herz
https://www.readbyqxmd.com/read/28992189/vitamin-k-antagonist-use-and-mortality-in-dialysis-patients
#7
Pauline W M Voskamp, Maarten B Rookmaaker, Marianne C Verhaar, Friedo W Dekker, Gurbey Ocak
Background: The risk-benefit ratio of vitamin K antagonists for different CHA 2 DS 2 -VASc scores in patients with end-stage renal disease treated with dialysis is unknown. The aim of this study was to investigate the association between vitamin K antagonist use and mortality for different CHA 2 DS 2 -VASc scores in a cohort of end-stage renal disease patients receiving dialysis treatment. Methods: We prospectively followed 1718 incident dialysis patients. Hazard ratios were calculated for all-cause and cause-specific (stroke, bleeding, cardiovascular and other) mortality associated with vitamin K antagonist use...
August 2, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28992017/digestible-metabolizable-and-net-energy-of-camelina-cake-fed-to-growing-pigs-and-additivity-of-energy-in-mixed-diets
#8
J W Kim, B Koo, C M Nyachoti
This experiment was conducted to determine the DE, ME, and NE contents of camelina cake (CC) and to test the hypothesis that dietary glucosinolates originating from CC will affect the additivity of energy in mixed diets containing different inclusion levels of corn, soybean meal (SBM), and CC. A total of 30 growing barrows ([Yorkshire × Landrace] × Duroc) with a mean BW of 16.8 kg (SD 1.4) were randomly allotted to 1 of 5 treatments with 6 replicates per treatment. Pigs were fed experimental diets for 16 d, including 10 d for adaptation and 6 d for total collection of feces and urine...
September 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28978540/functional-vitamin-b-6-status-and-long-term-mortality-in-renal-transplant-recipients
#9
Isidor Minović, Anna van der Veen, Martijn van Faassen, Ineke J Riphagen, Else van den Berg, Claude van der Ley, António W Gomes-Neto, Johanna M Geleijnse, Manfred Eggersdorfer, Gerjan J Navis, Ido P Kema, Stephan Jl Bakker
Background: Low plasma concentrations of pyridoxal 5'-phosphate (PLP) are common in renal transplant recipients (RTRs) and confer increased risk of long-term mortality. To our knowledge, it is not known whether low plasma PLP concentrations have functional (i.e., intracellular) consequences and, if so, whether such consequences are associated with increased risk of mortality.Objectives: We assessed the association of plasma PLP with functional vitamin B-6 status and explored the potential association of functional vitamin B-6 status with long-term mortality in RTRs...
October 4, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28977620/case-series-of-infantile-tremor-syndrome-in-tertiary-care-paediatric-centre-from-southern-india
#10
Vykuntaraju K Gowda, Vinyasa Kolli, Asha Benakappa, Varunvenkat M Srinivasan, Sanjay K Shivappa, Naveen Benakappa
Introduction: Infantile tremor syndrome (ITS) is characterized by anaemia, skin depigmentation, tremors and developmental delay. The lack of sufficient literature on ITS and its conflicting association with vitamin B12 deficiency made us present this article. Objective: The objective of this study is to describe demographic, clinical and laboratory profile and outcome of ITS. Methods: This is a retrospective chart review of all children presenting with typical features of ITS attending a tertiary paediatric centre in southern India between January 2014 and January 2017...
July 27, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28975362/significant-bone-loss-after-stopping-long-term-denosumab-treatment-a-post-freedom-study
#11
M B Zanchetta, J Boailchuk, F Massari, F Silveira, C Bogado, J R Zanchetta
We evaluate 38 elderly women who had received long-term denosumab treatment after stopping the drug. Taking into account the gain during treatment and the loss after stopping treatment, they lost 35.5% of the total gain in the spine, 44.6% of the total gain in the femoral neck, and 103.3% in the total hip. INTRODUCTION: Denosumab (DMAb) is a soluble inhibitor of the receptor activator of nuclear factor-kappaB ligand (RANKL) and, therefore, does not incorporate into the bone matrix. Consistently, DMAb discontinuation is associated with reversal of the effects attained with treatment...
October 3, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28971606/methionine-and-vitamin-b-complex-ameliorate-antitubercular-drugs-induced-toxicity-in-exposed-patients
#12
Kennedy I Amagon, Olufunsho Awodele, Abidemi J Akindele
Tuberculosis therapy utilizes drugs that while effective cause treatment-related toxicity. Modulation of antitubercular drugs-induced toxicity by methionine and vitamin B-complex in patients was evaluated. 285 treatment-naïve tuberculosis patients at the Chest Clinics of Infectious Diseases Hospital, Yaba and General Hospital, Lagos in Lagos, Nigeria was prospectively recruited and allotted into test (antitubercular medicines, methionine and vitamin B-complex) and control groups (antitubercular medicines)...
October 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28971236/gender-specific-association-between-dietary-acid-load-and-total-lean-body-mass-and-its-dependency-on-protein-intake-in-seniors
#13
A M Faure, K Fischer, B Dawson-Hughes, A Egli, H A Bischoff-Ferrari
Diet-related mild metabolic acidosis may play a role in the development of sarcopenia. We investigated the relationship between dietary acid load and total lean body mass in male and female seniors age ≥ 60 years. We found that a more alkaline diet was associated with a higher %TLM only among senior women. INTRODUCTION: The aim of this study was to determine if dietary acid load is associated with total lean body mass in male and female seniors age ≥ 60 years. METHODS: We investigated 243 seniors (mean age 70...
October 2, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28969507/societal-costs-of-micronutrient-deficiencies-in-6-to-59-month-old-children-in-pakistan
#14
Simon Wieser, Beatrice Brunner, Christina Tzogiou, Rafael Plessow, Michael B Zimmermann, Jessica Farebrother, Sajid Soofi, Zaid Bhatti, Imran Ahmed, Zulfiqar A Bhutta
BACKGROUND: In Pakistan, nearly half of children younger than 5 years are stunted and 1 in 3 is underweight. Micronutrient deficiencies, a less visible form of undernutrition, are also endemic. They may lead to increased morbidity and mortality as well as to impaired cognitive and physical development. OBJECTIVE: To estimate the lifetime costs of micronutrient deficiencies in Pakistani children aged between 6 and 59 months. METHODS: We develop a health economic model of the lifetime health and cost consequences of iodine, iron, vitamin A, and zinc deficiencies...
January 1, 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28958614/thiamine-and-riboflavin-inhibit-production-of-cytokines-and-increase-the-anti-inflammatory-activity-of-a-corticosteroid-in-a-chronic-model-of-inflammation-induced-by-complete-freund-s-adjuvant
#15
Raquel R Menezes, Adriana M Godin, Felipe Fernandes Rodrigues, Giovanna M E Coura, Ivo S F Melo, Ana Mercy S Brito, Caryne M Bertollo, Tony P Paulino, Milene A Rachid, Renes R Machado, Márcio M Coelho
BACKGROUND: The effects induced by thiamine and riboflavin, isolated or in association with corticosteroids, in models of chronic inflammation are not known. Thus, we evaluated the effect induced by these B vitamins, isolated or in association with dexamethasone, on the mechanical allodynia, paw edema and cytokine production induced by complete Freund's adjuvant (CFA) in rats. METHODS: Chronic inflammation was induced by two injections of CFA. Nociceptive threshold, paw volume and body temperature were evaluated for 21days...
April 23, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28954742/outcomes-of-orthopedic-surgery-in-a-cohort-of-49-patients-with-x-linked-hypophosphatemic-rickets-xlhr
#16
A Gizard, A Rothenbuhler, Z Pejin, G Finidori, C Glorion, B de Billy, A Linglart, P Wicart
BACKGROUND: X-linked hypophosphatemic rickets (XLHR) is due to mutations in PHEX leading to unregulated production of FGF23 and hypophosphatemia. XLHR is characterized by leg bowing of variable severity. Phosphate supplements and oral vitamin analogs, partially or, in some cases, fully restore the limb straightness. Surgery is the alternative for severe or residual limb deformities. OBJECTIVE: To retrospectively assess the results of surgical limb correction in XLHR (osteotomies and bone alignment except for 3 transient hemiepiphysiodesis)...
November 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28954197/vitamin-d-analogues-with-a-p-hydroxyphenyl-group-at-the-c25-position-crystal-structure-of-vitamin-d-receptor-ligand-binding-domain-complexed-with-the-ligand-explains-the-mechanism-underlying-full-antagonistic-action
#17
Akira Kato, Makiko Yamao, Yuta Hashihara, Hiroaki Ishida, Toshimasa Itoh, Keiko Yamamoto
Vitamin D receptor (VDR) antagonists can be classified into two categories: the first category of VDR antagonists, which do not stabilize the helix 11-12, and the second category of antagonists, which destabilize the helix 6-7 region. To elucidate the mechanism underlying the first category antagonists by using the crystal structure, we designed and synthesized several VDR ligands with a p-hydroxyphenyl group at the C25-position. Of these, 22S-butyl-25-carbonyl analogue 5b and 25-di-p-hydoroxyphenyl analogues 6a,b showed strong antagonistic activity...
September 27, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28925036/combining-food-based-dietary-recommendations-using-optifood-with-zinc-fortified-water-potentially-improves-nutrient-adequacy-among-4-to-6-year-old-children-in-kisumu-west-district-kenya
#18
Prosper Kujinga, Karin J Borgonjen-van den Berg, Cecilia Superchi, Hermine J Ten Hove, Elizabeth Opiyo Onyango, Pauline Andang'o, Valeria Galetti, Michael B Zimmerman, Diego Moretti, Inge D Brouwer
Children in developing countries often face multiple micronutrient deficiencies. Introduction of zinc-fortified water can increase zinc intake, but additional recommendations are required to address overall diet nutrient adequacy. We developed and tested food-based recommendations (FBRs) that included zinc-fortified water for children aged between 4 and 6 years from rural Kenya to achieve the best possible nutrient adequacy. Dietary intakes of 60 children aged 4-6 years, from Kisumu West district, Kenya, were assessed using a quantitative multipass 24-hr recall...
September 19, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28924002/variations-in-infant-and-childhood-vitamin-d-supplementation-programs-across-europe-and-factors-influencing-adherence
#19
Suma Uday, Ardita Kongjonaj, Magda Aguiar, Ted Tulchinsky, Wolfgang Hoegler
BACKGROUND: Nutritional rickets is a growing global public health concern despite existing prevention programs and health policies. We aimed to compare infant and childhood vitamin D supplementation policies, implementation strategies and practices across Europe and explore factors influencing adherence. METHODS: European Society for Paediatric Endocrinology Bone and Growth Plate Working Group members and other specialists completed a questionnaire on country-specific vitamin D supplementation policy and child healthcare programs, socioeconomic factors, policy implementation strategies, and adherence...
September 18, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28917239/screening-for-inadequate-dietary-vitamin-b-12-intake-in-south-asian-women-using-a-nutrient-specific-semi-quantitative-food-frequency-questionnaire
#20
Gael Janine Mearns, Elaine Carolyn Rush
BACKGROUND AND OBJECTIVES: A high prevalence of vitamin B-12 (B-12) deficiency among young women of South Asian origin predisposes to significant health risks for these women and their future offspring. Vegetarian or low-meat based dietary practices contribute to B-12 deficiency. This study validated a nutrient-specific, semi-quantitative food frequency questionnaire (B12FFQ), developed to estimate dietary B-12 intake in South Asian women. METHODS AND STUDY DESIGN: The B12FFQ was developed, then tested in 60 apparently healthy South Asian women aged 18-50 years, living in Auckland, New Zealand...
2017: Asia Pacific Journal of Clinical Nutrition
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