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"frank's sign"

Anay R Patel, Patrick Sweeney, George Ochenjele, Richard Wixson, S David Stulberg, Lalit M Puri
Polyethylene wear and subsequent osteolysis are major obstacles to the long-term success of total hip arthroplasty (THA). We conducted a study to determine the incidence of loose acetabular components that did not show frank signs of loosening on either plain radiography or computed tomography (CT), or radiographically silent loosening (RSL). In this retrospective study, we evaluated patients who underwent revision THA and were evaluated with plain radiography and CT between 2000 and 2012. Any patient with imaging that showed signs of component movement was excluded...
September 2015: American Journal of Orthopedics
Shoaib Bilal Fareedy, Ranjan Pathak, Ahmed Salman, Richard Alweis
No abstract text is available yet for this article.
2015: Journal of Community Hospital Internal Medicine Perspectives
C-H Lo, W-S Lin
No abstract text is available yet for this article.
September 2015: QJM: Monthly Journal of the Association of Physicians
Risheng Xu, John Pham
No abstract text is available yet for this article.
2014: BMJ Case Reports
H S Füessl
No abstract text is available yet for this article.
April 3, 2014: MMW Fortschritte der Medizin
George Griffing
A 59-year-old man with long-standing hypertension presented with exertional chest pain. An electrocardiogram and cardiac stress testing were unremarkable. Coronary angiography, however, revealed substantial stenosis, and two stents were placed. The patient's recovery was uneventful, and he has..
March 6, 2014: New England Journal of Medicine
Avi Ohry
Physical diagnosis is considered to be a cornerstone in clinical medicine. Examination of the ears is frequently forgotten although, in many clinical situations, it may help: in gout (tophi), lupus, congenital anomalies, trauma and in local malignancies. We may add another physical-acquired sign: the Frank's sign in which a diagonal notch in the ear lobe is found in patients with coronary heart disease.
March 2011: Harefuah
Leopoldo Rubaltelli, Valeria Beltrame, Alberto Tregnaghi, Elena Scagliori, Anna Chiara Frigo, Roberto Stramare
OBJECTIVE: The aim of this study was to ascertain the utility of contrast-enhanced ultrasound in assessing the significance of focal cortical thickening in the lymph nodes of patients followed up after surgery for cutaneous melanoma. MATERIALS AND METHODS: Ultrasound was used to examine 460 consecutive patients to identify nodes with focal hypoechoic cortical thickening. Patients whose nodes revealed these features underwent contrast-enhanced ultrasound and ultrasound-guided fine-needle aspiration cytology (FNAC) focusing on the area of cortical thickening...
January 2011: AJR. American Journal of Roentgenology
István Pataki, Myroslav Horzov, William Chanis
The complicated diaphragmatic hernia of traumatic origin, is a life-threatening condition. In most cases, the diaphragmatic rupture is caused by blunt trauma that affects the chest or abdomen, but penetrating wounds may represent also an etiological factor. Traffic accidents are primarily involved, in time of peace. We report a case of a 59-year-old male patient, who had a traffic accident 16 years before his admission to the emergency department. In these years he produced vague dyspeptic symptoms and was treated several times for pleural effusions and COPD...
June 2010: Magyar Sebészet
Astrid Jeibmann, Martin Hasselblatt, Joachim Gerss, Brigitte Wrede, Rupert Egensperger, Rudi Beschorner, Volkmar H J Hans, Christian H Rickert, Johannes E Wolff, Werner Paulus
The prognostic significance of atypical histologic features in choroid plexus tumors remains uncertain. Therefore, a series of 164 choroid plexus tumors was evaluated for the presence of atypical histologic features, including mitotic activity, increased cellularity, nuclear pleomorphism, blurring of papillary growth pattern, and necrosis. The impact of histopathologic and clinical features on the probability of recurrence and survival was investigated. Twenty-four tumors displaying frank signs of malignancy were diagnosed as choroid plexus carcinoma according to World Health Organization criteria...
November 2006: Journal of Neuropathology and Experimental Neurology
Yeon-Jeen Chang, Vijay Mittal, Stephen Remine, Harish Manyam, Mubashir Sabir, Todd Richardson, Shun Young
Carcinoma of the parathyroid is a rare malignancy that can be cured surgically if the proper diagnosis and treatment is given initially. Arriving to the clinical suspicion of a malignancy preoperatively is by far the most important step for a good prognosis. Our goal is to review the correlation between clinical and final histopathological findings that can arouse the suspicion of such malignancy and their true predictive value in the diagnosis. All patients that underwent surgical removal of the parathyroid mass between March of 1992 and March of 2003 were reviewed retrospectively at Providence Hospital and Medical Centers...
May 2006: American Surgeon
Herbert Pickell, Edward Klima, Tracy Love, Mark Kritchevsky, Ursula Bellugi, Gregory Hickok
Recent lesion studies have shown that left hemisphere lesions often give rise to frank sign language aphasias in deaf signers, whereas right hemisphere lesions do not, suggesting similar patterns of hemispheric asymmetry for signed and spoken language. We present here a case of a left-handed, deaf, life-long signer who became aphasic after a right-hemisphere lesion. The subject exhibits deficits in sign language comprehension and production typically associated with left hemisphere damaged signers. He also exhibits evidence of local versus global deficits similar to left-hemisphere lesioned hearing patients...
June 2005: Neurocase
Timothy Pastoor, Patrick Rose, Sara Lloyd, Richard Peffer, Trevor Green
Thiamethoxam (CGA293343; 3-(2-chloro-thiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylidene-N-nitroamine) was shown to increase the incidence of mouse liver tumors in an 18-month study; however, thiamethoxam was not hepatocarcinogenic in rats. Thiamethoxam is not genotoxic, and, given the late life generation of mouse liver tumors, suggests a time-related progression of key hepatic events that leads to the tumors. These key events were identified in a series of studies of up to 50 weeks that showed the time-dependent evolution of relatively mild liver dysfunction within 10 weeks of dosing, followed by frank signs of hepatotoxicity after 20 weeks, leading to cellular attrition and regenerative hyperplasia...
July 2005: Toxicological Sciences: An Official Journal of the Society of Toxicology
Liviu V Titu, Gerard Laden, Gerard M Purdy, Kevin R Wedgwood
Stomach rupture can occur as a consequence of the expansion of compressed air during rapid ascent after diving. We present the case of a middle-aged woman who suffered a gastric tear from surfacing too quickly after diving, and discuss the diagnosis and management of such patients by reviewing previously reported similar events. Gastric barotrauma should be suspected in divers who complain of abdominal pain, even in the absence of frank signs of peritoneal irritation. Although pneumoperitoneum is always present in these patients, it can also occur as a consequence of pulmonary barotrauma, making gastroscopy or radiological contrast studies, or both, essential for a definitive diagnosis...
2003: Surgery Today
T M Davis, M Balme, D Jackson, G Stuccio, D G Bruce
BACKGROUND: The diagonal ear lobe crease (ELC) has been suggested as a simple marker of vascular disease in the general population but there are few data from diabetic patients despite their increased risk of angiopathy. AIM: To determine whether the ELC is a clinically useful sign of coronary artery disease (CAD) or retinopathy in type 2 diabetes. METHODS: One thousand and twenty-two patients from the multi-ethnic urban catchment area of Fremantle Hospital in Western Australia were studied...
October 2000: Australian and New Zealand Journal of Medicine
J Emmerich
The non-invasive diagnosis of pulmonary emboli is based, in part, on evidencing a deep venous thrombosis (TVP-DVT); one of the principal features of thromboembolic disease with pulmonary emboli. Ultrasonic venograms have been introduced as the best non-invasive morphological examination for the diagnosis of DVT. Its sensitivity in subjects suspected of having pulmonary emboli (but having no frank signs of DVT) is inferior to that observed in cases where there is a clinical suspicion of DVT. On the other hand, only 70 per cent of subjects having pulmonary emboli have a DVT of the lower limbs on phlebography...
November 1999: Revue des Maladies Respiratoires
O Watanabe, M Torda, J Meldolesi
Neurosecretory PC12 cells were exposed in a variety of experimental conditions to nanomolar concentrations of alpha-latrotoxin purified from the venom of the black widow spider. When applied in a modified Ringer medium containing millimolar Ca2+ the toxin rapidly elicited a marked stimulation of exocytosis, as indicated by the appearance of typical images of granule-plasmalemma interaction and by the decreased density (number/unit area) of secretion granules in the cytoplasm. Without Ca2+ in the medium this early toxin effect was delayed and evolved less rapidly, but was still clearly appreciable...
November 1983: Neuroscience
A P van Nieuwstadt, J Verhoeff
The epidemiology of bovine herpesvirus 1 (BHV 1) infections was studied in 20 dairy herds. Periodic serological surveillance of these herds during three consecutive years (1980-82) was combined with clinical studies. In 19 herds seropositive cows were found indicating previous exposure to BHV 1. One herd had its first experience with BHV 1 during the study. No indication of virus circulation for at least three years was found in eight herds. In five herds an interval of 2 years without an indication of virus circulation was followed by infections in yearlings, first- and second-calf cows during the third year...
October 1983: Journal of Hygiene
J P Lesbre, B Castier, C Tribouilloy, B Labeille, C Isorni
The authors study the sensitivity, the specificity and the predicting value of Frank's sign (presence of a groove at the level of the earlobe) on a group of 172 patients undergoing a clinical examination, an EKG at rest and effort, and a selective coronary arteriogram for suspicion of coronary disease. The criteria retained for the diagnosis of coronary disease is the presence of stenosis superior or equal to 75 p. cent in one of the three main coronary vascular trunks. Statistical studies using the CHI 2 test reveal a highly significant association between Frank's sign and coronary disease (p less than 0...
January 1987: Annales de Cardiologie et D'angéiologie
J M Isner, K Rosenfield, C J White, S Ramee, M Kearney, A Pieczek, R E Langevin, S Razvi
BACKGROUND: The pathological consequences of cardiovascular laser irradiation have been studied extensively in vitro. Previous in vivo studies of laser-induced injury have included analyses of acute and/or chronic findings in experimental animals. Little information, however, is available regarding the acute effects of laser irradiation of human vascular tissues in vivo. METHODS AND RESULTS: To determine the acute pathology resulting from laser irradiation of human vascular tissue in vivo, specimens retrieved from 23 patients by directional atherectomy immediately after laser angioplasty (19 peripheral and four coronary) were examined by light microscopy...
June 1992: Circulation
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