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Nasopharygneal carcinoma

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https://www.readbyqxmd.com/read/21224300/evaluation-of-radiation-induced-changes-to-parotid-glands-following-conventional-radiotherapy-in-patients-with-nasopharygneal-carcinoma
#1
V W C Wu, M T C Ying, D L W Kwong
OBJECTIVES: Xerostomia is a common post-radiotherapy (post-RT) complication in nasopharyngeal carcinoma (NPC) patients. This study evaluated the relation of post-RT parotid gland changes with the dose received. METHODS: Data from 18 NPC patients treated by radiotherapy between 1997 and 2001 were collected. Parotid gland volumes were measured and compared between their pre-RT and post-RT CT images; both sets of CT were conducted with the same scanning protocol. Doppler ultrasound was used to assess the haemodynamic condition of the glands after radiotherapy...
September 2011: British Journal of Radiology
https://www.readbyqxmd.com/read/18246791/-radiosensitization-of-paclitaxel-combined-with-radiation-on-nasopharygneal-carcinoma-cells-cne-i-in-vitro
#2
Zhi-Yong Yuan, Wei-Zhi Yang, Jing Jin, Li Gao, Xin-Fan Liu, Guo-Zhen Xu
OBJECTIVE: To evaluate the radiosensitization of paclitaxel combined with radiation on nasopharygneal carcinoma cells( CNE-I) in vitro. METHODS: Human CNE-I cells were used for this study. Clonogenic assay was used to determine the drug dose of IC10, IC50 and IC90 for CNE-I Cells. The cells treated with different concentration of paclitaxel for 24 hours before or after radiation (dose ranged from 0 - 10 Gy ) were used to evaluate the radiosensitizing effect of paclitaxel combined with radiation...
September 2007: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/12764773/-the-expression-in-situ-of-transforming-growth-factor-beta-s-their-receptors-and-tgf-beta-receptor-interacting-protein-1-in-nasopharygneal-carcinoma
#3
L Bin, C Hu, F Zhan
OBJECTIVE: To study the expression of transforming growth factor(TGF) beta s, their receptors and TGF beta-receptor interacting protein-1 (TRIP-1) in nasopharygneal carcinoma. METHODS: Immunohistochemical technology and in situ hybridization methods were adopted to detect the TRIP-1 mRNA and 3 kinds of TGF beta isoforms and 2 kinds of TGF beta receptors protein in the same biopsy specimen. RESULTS: The positive expression of TGF beta 1, TGF beta 2, TGF beta 3, TGF beta R I and TGF beta R II was stronger in the tumor adjacent epithelium than in the tumor itself, which were 65...
August 1999: Zhonghua Er Bi Yan Hou Ke za Zhi
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