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https://www.readbyqxmd.com/read/28329603/job-recruitment
#1
University Of California Davis School Of Medicine
The University of California Davis, School of Medicine, Department of Dermatology is recruiting for a full-time position at the Associate or Full Professor level in the Clinical X Series or Health Sciences Clinical Professor (HSCP) Series. The successful candidate is nominated to be the holder of the Frederick G. Novy, Jr. M.D Endowed Professorship. Appointees to the ClinX series are expected to conduct independent research. Both series require significant participation in teaching and University/public service...
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28317660/safety-tolerability-and-efficacy-of-intradermal-rabies-immunization-with-debioject%C3%A2
#2
Paul Vescovo, Nils Rettby, Nirinarilala Ramaniraka, Julie Liberman, Karen Hart, Astrid Cachemaille, Laurent-Dominique Piveteau, Reto Zanoni, Pierre-Alexandre Bart, Giuseppe Pantaleo
In a single-center study, 66 healthy volunteers aged between 18 and 50years were randomized to be immunized against rabies with three different injection routes: intradermal with DebioJect™ (IDJ), standard intradermal with classical needle (IDS), also called Mantoux method, and intramuscular with classical needle (IM). "Vaccin rabique Pasteur®" and saline solution (NaCl 0.9%) were administered at D0, D7 and D28. Antigen doses for both intradermal routes were 1/5 of the dose for IM. Tolerability, safety and induced immunogenicity of IDJ were compared to IDS and IM routes...
March 27, 2017: Vaccine
https://www.readbyqxmd.com/read/28315612/ultrasound-assessment-of-peripheral-nerve-pathology-in-neurofibromatosis-type-1-and-2
#3
Natalie Winter, Tim W Rattay, Hubertus Axer, Eva Schäffer, Bernhard F Décard, Isabel Gugel, Martin Schuhmann, Alexander Grimm
OBJECTIVE: The neurofibromatoses (NF) type 1 and 2 are hereditary tumor predisposition syndromes caused by germline mutations in the NF1 and NF2 tumor suppressor genes. In NF1 and 2, peripheral nerve tumors occur regularly. For further characterizing nerve ultrasound was performed in patients with NF1 and 2. METHODS: Patients with established diagnosis of NF1 (n=27) and NF2 (n=10) were included. Ultrasound of peripheral nerves and cervical roots was performed during routine follow-up visits...
February 20, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28300372/lung-volume-reproducibility-under-abc-control-and-self-sustained-breath-holding
#4
Evangelia Kaza, Alex Dunlop, Rafal Panek, David J Collins, Matthew Orton, Richard Symonds-Tayler, Dualta McQuaid, Erica Scurr, Vibeke Hansen, Martin O Leach
An Active Breathing Coordinator (ABC) can be employed to induce breath-holds during CT imaging and radiotherapy of lung, breast and liver cancer, and recently during lung cancer MRI. The apparatus measures and controls respiratory volume, hence subject lung volume reproducibility is its principal measure of effectiveness. To assess ABC control quality, the intra-session reproducibility of ABC-induced lung volumes was evaluated and compared with that reached by applying the clinical standard of operator-guided self-sustained breath-holds on healthy volunteers during MRI...
March 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28284926/moderate-short-term-local-hyperglycemia-attenuates-forearm-endothelium-dependent-vasodilation-after-transient-ischemia-reperfusion-in-human-volunteers
#5
Thomas J Ebert, Jutta Novalija, Jill A Barney, Toni D Uhrich, Shahbaz R Arain, Julie K Freed, Paul S Pagel
OBJECTIVE: Acute hyperglycemia causes endothelial dysfunction in diabetic patients, abolishes ischemic pre- and postconditioning, and is an independent predictor of adverse outcome after myocardial infarction in nondiabetic patients. Its effects on endothelial-dependent vasodilation are controversial in healthy subjects. The authors studied the effect of moderate short-term local hyperglycemia on forearm endothelium-dependent vasodilation in healthy volunteers. DESIGN: Randomized, crossover, blinded, 2-visit, pilot design...
December 2, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28275375/a-comparative-phase-i-study-of-combination-homologous-subtype-c-dna-mva-and-env-gp140-protein-adjuvant-hiv-vaccines-in-two-immunization-regimes
#6
Sarah Joseph, Killian Quinn, Aldona Greenwood, Alethea V Cope, Paul F McKay, Peter J Hayes, Jakub T Kopycinski, Jill Gilmour, Aleisha N Miller, Christof Geldmacher, Yuka Nadai, Mohamed I M Ahmed, David C Montefiori, Len Dally, George Bouliotis, David J M Lewis, Roger Tatoud, Ralf Wagner, Mariano Esteban, Robin J Shattock, Sheena McCormack, Jonathan Weber
There remains an urgent need for a prophylactic HIV vaccine. We compared combined MVA and adjuvanted gp140 to sequential MVA/gp140 after DNA priming. We expected Env-specific CD4+ T-cells after DNA and MVA priming, and Env-binding antibodies in 100% individuals after boosting with gp140 and that combined vaccines would not compromise safety and might augment immunogenicity. Forty volunteers were primed three times with DNA plasmids encoding (CN54) env and (ZM96) gag-pol-nef at 0, 4 and 8 weeks then boosted with MVA-C (CN54 env and gag-pol-nef) and glucopyranosyl lipid adjuvant-aqueous formulation (GLA-AF) adjuvanted CN54gp140...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28275087/community-health-workers-as-social-marketers-of-injectable-contraceptives-a-case-study-from-ethiopia
#7
REVIEW
Karen Weidert, Amanuel Gessessew, Suzanne Bell, Hagos Godefay, Ndola Prata
Ethiopia has made notable progress in increasing awareness and knowledge of family planning and is considered a success story among funders and program planners. Yet unmet need among rural women (28.6%) is almost double that of urban women (15.5%), with a wide gap in total fertility rate depending on urban (2.6) or rural (5.5) residence. This study investigates the impact of a service delivery model that combines community-based distribution (CBD) of contraception with social marketing in Tigray, Ethiopia, to create a more sustainable approach to CBD...
March 8, 2017: Global Health, Science and Practice
https://www.readbyqxmd.com/read/28272697/research-on-the-relations-between-the-variation-of-mirna-184-before-and-after-treatment-of-acute-myocardial-infarction-and-prognosis
#8
Z-H Liu, X-P Sun, S-L Zhou, H-X Wang
OBJECTIVE: Several miRNAs have been shown to be released into the circulation and play roles during acute myocardial infarction (AMI). This study aimed at detecting the variation of miRNA-184 before and after treatment of acute myocardial infarction and assessing its prognostic value. PATIENTS AND METHODS: 72 AMI patients participated in the study, alongside 10 patients with stable coronary disease and 10 healthy volunteers for comparison. The expression levels of miRNA-184 were measured in AMI patients at 6 h, 12 h, 48 h, 7 d, and 14 d after the onset of symptoms, using blood samples and an RT-PCR method...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28271554/examination-of-wound-healing-after-curettage-by-multiphoton-tomography-of-human-skin-in-vivo
#9
S Springer, M Zieger, A Böttcher, J Lademann, M Kaatz
BACKGROUND: The multiphoton tomography (MPT) has evolved into a useful tool for the non-invasive investigation of morphological and biophysical characteristics of human skin in vivo. Until now, changes of the skin have been evaluated mainly by using clinical and histological techniques. In this study, the progress of wound healing was investigated by MPT over 3 weeks with a final examination after 24 months. Especially, the collagen degradation, reepithelization and tissue formation were examined...
March 7, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28270201/exploration-of-haplotype-research-consortium-imputation-for-genome-wide-association-studies-in-20-032-generation-scotland-participants
#10
Reka Nagy, Thibaud S Boutin, Jonathan Marten, Jennifer E Huffman, Shona M Kerr, Archie Campbell, Louise Evenden, Jude Gibson, Carmen Amador, David M Howard, Pau Navarro, Andrew Morris, Ian J Deary, Lynne J Hocking, Sandosh Padmanabhan, Blair H Smith, Peter Joshi, James F Wilson, Nicholas D Hastie, Alan F Wright, Andrew M McIntosh, David J Porteous, Chris S Haley, Veronique Vitart, Caroline Hayward
BACKGROUND: The Generation Scotland: Scottish Family Health Study (GS:SFHS) is a family-based population cohort with DNA, biological samples, socio-demographic, psychological and clinical data from approximately 24,000 adult volunteers across Scotland. Although data collection was cross-sectional, GS:SFHS became a prospective cohort due to of the ability to link to routine Electronic Health Record (EHR) data. Over 20,000 participants were selected for genotyping using a large genome-wide array...
March 7, 2017: Genome Medicine
https://www.readbyqxmd.com/read/28253839/effectiveness-of-integrated-care-on-delaying-progression-of-stage-3-4-chronic-kidney-disease-in-rural-communities-of-thailand-escort-study-a-cluster-randomized-controlled-trial
#11
Teerayuth Jiamjariyapon, Atiporn Ingsathit, Krit Pongpirul, Kotcharat Vipattawat, Suphattra Kanchanakorn, Akhathai Saetie, Duangjit Kanistanon, Patimaporn Wongprompitak, Vinai Leesmidt, Watcharapong Watcharasaksilp, Wei Wang, Anil K Chandraker, Kriang Tungsanga
BACKGROUND: In developing countries, renal specialists are scarce and physician-to-patient contact time is limited. While conventional hospital-based, physician-oriented approach has been the main focus of chronic kidney disease (CKD) care, a comprehensive multidisciplinary health care program (Integrated CKD Care) has been introduced as an alternate intervention to delay CKD progression in a community population. The main objective is to assess effectiveness of Integrated CKD Care in delaying CKD progression...
March 2, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28230696/the-call-to-service-is-personal-from-vietnam-to-red-cross-volunteer
#12
Robert J Hassmiller
Updated several times a week with posts by a wide variety of authors, AJN's blog Off the Charts allows us to provide more timely-and often more personal-perspectives on professional, policy, and clinical issues. Best of the Blog will be a regular column to bring AJN readers recent posts that we think deserve a wider audience. To read more, please visit: www.ajnoffthecharts.com.
March 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28228424/widespread-sucralose-exposure-in-a-randomized-clinical-trial-in-healthy-young-adults
#13
Allison C Sylvetsky, Peter J Walter, H Martin Garraffo, Kim Robien, Kristina I Rother
Background: Low-calorie sweeteners (LCSs) are found in many foods and beverages, but consumers may not realize their presence, and their role in appetite, weight, and health is controversial. Although consumption limits based on toxicologic safety are well established, the threshold required to exert clinically relevant metabolic effects is unknown.Objectives: This study aimed to determine whether individuals who do not report consumption of LCSs can be correctly characterized as "unexposed" and to investigate whether instructions to avoid LCSs are effective in minimizing exposure...
February 22, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28192745/accepted-monitoring-or-endured-quarantine-ebola-contacts-perceptions-in-senegal
#14
Alice Desclaux, Dioumel Badji, Albert Gautier Ndione, Khoudia Sow
During the 2014-2016 West Africa Ebola epidemic, transmission chains were controlled through contact tracing, i.e., identification and follow-up of people exposed to Ebola cases. WHO recommendations for daily check-ups of physical symptoms with social distancing for 21 days were unevenly applied and sometimes interpreted as quarantine. Criticisms arose regarding the use of coercion and questioned contact tracing on ethical grounds. This article aims to analyze contact cases' perceptions and acceptance of contact monitoring at the field level...
February 7, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28167957/histological-and-immunohistochemical-evaluation-of-the-efficacy-of-a-new-cosmetic-formulation-in-the-treatment-of-skin-photoaging
#15
M T Truchuelo, N Jiménez, L Miguel-Gomez, A Hermosa, N Sánchez-Neila, J Cuevas
Objective. Mechanism of action of cosmetic products is not often studied. The aim of this study is to determine the histological, immunohistochemical, and clinical changes of a new cosmetic formulation. Methods. Prospective, single-blind, patient-controlled, randomized study in 10 volunteers with mild to moderate skin photoaging on the back of their hands. The product was applied on one hand and a standard cream on the other hand, twice a day for three months. Standardized photographs were taken on basal (T0) and final visit (T1) and skin biopsies were performed...
2017: Dermatology Research and Practice
https://www.readbyqxmd.com/read/28164458/comparison-of-hair-removal-efficacy-and-side-effect-of-neodymium-yttrium-aluminum-garnet-laser-and-intense-pulsed-light-systems-18-month-follow-up
#16
Georgina Zita Szima, Eszter Anna Janka, Anikó Kovács, Blanka Bortély, Edina Bodnár, Irina Sawhney, Éva Szabó, Éva Remenyik
BACKGROUND: Photothermal destruction of hair shaft melanin with intense pulsed light (IPL) and neodymium:yttrium-aluminum-garnet (Nd:YAG) laser has become an effective treatment of hair removal. AIMS: Our aim was to compare efficacy, satisfactory levels, safety, and side effects of Nd:YAG and IPL in hair reduction. METHODS: This was a prospective randomized intrapatient, right-left, assessor-blinded comparison of Nd:YAG vs IPL. There were 38 volunteers recruited...
February 6, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28157138/expectancy-reduces-symptoms-but-not-functional-impairment-following-exercise-induced-musculoskeletal-injury
#17
William C Hedderson, Geoffrey C Dover, Steven Z George, Joshua A Crow, Paul A Borsa
OBJECTIVES: To quantify the extent to which the participant-provider interaction influences the response to sham treatment following exercised-induced acute musculoskeletal pain. METHODS: Forty participants between the ages of 18 and 35 volunteered for the study. Participants came to the laboratory for three test sessions 48-hours apart (Day 1, 3 and 5). During the initial session, baseline measures were assessed and participants underwent a fatigue protocol for the biceps brachii...
February 2, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28152160/new-or-worsening-symptoms-and-signs-in-community-dwelling-persons-with-dementia-incidence-and-relation-to-use-of-acute-medical-services
#18
Philip D Sloane, Christopher H Schifeling, Anna S Beeber, Kimberly T Ward, David Reed, Lisa P Gwyther, Bobbi Matchar, Sheryl Zimmerman
OBJECTIVES: To understand the range of symptoms that present to family caregivers of community-dwelling persons with Alzheimer's disease and related dementias (ADRD). DESIGN: Six-month longitudinal prospective study to identify the incidence of new or worsening symptoms and their association with acute care medical service use. SETTING: Community-based sample of volunteers from multiple states. PARTICIPANTS: A total of 136 patient-caregiver dyads with a range of dementia severity...
February 2, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28118310/ratings-of-perceived-exertion-during-acute-resistance-exercise-performed-at-imposed-and-self-selected-loads-in-recreationally-trained-women
#19
Joshua A Cotter, Matthew J Garver, Taylor K Dinyer, Ciaran M Fairman, Brian C Focht
Resistance exercise (RE) is commonly employed to elicit skeletal muscle adaptation. Relative intensity of a training load links closely with the outcomes of regular RE. This study examined the RPE responses to acute bouts of RE using imposed (40% and 70% of 1RM) and self-selected loads (SS) in recreationally trained women. Twenty physically active women (23.15 ±2.92 yrs.) who reported regular RE training of at least three weekly sessions for the past year, volunteered to participate. During the initial visit, participants completed one repetition maximum (1RM) testing on four exercises in the following order: leg extension, chest press, leg curl, and lat pull-down...
January 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28115837/effects-of-tai-chi-qigong-on-psychosocial-well-being-among-hidden-elderly-using-elderly-neighborhood-volunteer-approach-a-pilot-randomized-controlled-trial
#20
Aileen Wk Chan, Doris Sf Yu, K C Choi
PURPOSE: To test the feasibility and preliminary effectiveness of a tai chi qigong program with the assistance of elderly neighborhood volunteers in strengthening social networks and enhancing the psychosocial well-being of hidden elderly. PATIENTS AND METHODS: "Hidden elderly" is a term used to describe older adults who are socially isolated and refuse social participation. This pilot randomized controlled trial recruited 48 older adults aged 60 or above who did not engage in any social activity...
2017: Clinical Interventions in Aging
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