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https://www.readbyqxmd.com/read/28438003/wavelength-multicasting-through-four-wave-mixing-with-an-optical-comb-source
#1
Hong-Fu Ting, Ke-Yao Wang, Jasper R Stroud, Keith G Petrillo, Hongcheng Sun, Amy C Foster, Mark A Foster
Based on four-wave mixing (FWM) with an optical comb source (OCS), we experimentally demonstrate 26-way or 15-way wavelength multicasting of 10-Gb/s differential phase-shift keying (DPSK) data in a highly-nonlinear fiber (HNLF) or a silicon waveguide, respectively. The OCS provides multiple spectrally equidistant pump waves leading to a multitude of FWM products after mixing with the signal. We achieve error-free operation with power penalties less than 5.7 dB for the HNLF and 4.2 dB for the silicon waveguide, respectively...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437950/maximum-likelihood-sequence-estimation-for-optical-complex-direct-modulation
#2
Di Che, Feng Yuan, William Shieh
Semiconductor lasers are versatile optical transmitters in nature. Through the direct modulation (DM), the intensity modulation is realized by the linear mapping between the injection current and the light power, while various angle modulations are enabled by the frequency chirp. Limited by the direct detection, DM lasers used to be exploited only as 1-D (intensity or angle) transmitters by suppressing or simply ignoring the other modulation. Nevertheless, through the digital coherent detection, simultaneous intensity and angle modulations (namely, 2-D complex DM, CDM) can be realized by a single laser diode...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437929/robust-overlay-metrology-with-differential-mueller-matrix-calculus
#3
Xiuguo Chen, Honggang Gu, Hao Jiang, Chuanwei Zhang, Shiyuan Liu
Overlay control is of vital importance to good device performances in semiconductor manufacturing. In this work, the differential Mueller matrix calculus is introduced to investigate the Mueller matrices of double-patterned gratings with overlay displacements, which helps to reveal six elementary optical properties hidden in the Mueller matrices. We find and demonstrate that, among these six elementary optical properties, the linear birefringence and dichroism, LB' and LD', along the ± 45° axes show a linear response to the overlay displacement and are zero when the overlay displacement is absent at any conical mounting...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437900/model-and-reconstruction-of-a-k-edge-contrast-agent-distribution-with-an-x-ray-photon-counting-detector
#4
Bo Meng, Wenxiang Cong, Yan Xi, Bruno De Man, Jian Yang, Ge Wang
Contrast-enhanced computed tomography (CECT) helps enhance the visibility for tumor imaging. When a high-Z contrast agent interacts with X-rays across its K-edge, X-ray photoelectric absorption would experience a sudden increment, resulting in a significant difference of the X-ray transmission intensity between the left and right energy windows of the K-edge. Using photon-counting detectors, the X-ray intensity data in the left and right windows of the K-edge can be measured simultaneously. The differential information of the two kinds of intensity data reflects the contrast-agent concentration distribution...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437887/influence-of-sinomenine-upon-mesenchymal-stem-cells-in-osteoclastogenesis
#5
Biao Zhou, Xiaolong Lu, Zhi Tang, Dan Liu, Youliang Zhou, Peng Zeng, Hui Xiong
With the advent of aging, the morbidity rates of such diseases as osteoarthritis, rheumatoid arthritis, and osteoporosis has witnessed a significant increase. As a common rattan drug, sinomenine (SIN) has been widely applied for the treatment of various arthritic diseases in traditional Chinese medicine (TCM) clinics. Given that SIN has been reported to inhibit the expression of Prostaglandin E2 (PGE2) in several types of cells, in this study, the influence of SIN treatment on PGE2 expression in mesenchymal stem cells (MSCs), thereby changing the osteoprotegerin (OPG) receptor/activator for the nuclear factor-κ B ligand (RANKL) ratio, was investigated...
April 19, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28437860/chronic-inhibition-of-fatty-acid-amide-hydrolase-by-urb597-produces-differential-effects-on-cardiac-performance-in-normotensive-and-hypertensive-rats
#6
Anna Pedzinska-Betiuk, Jolanta Weresa, Marek Toczek, Marta Baranowska-Kuczko, Irena Kasacka, Ewa Harasim-Symbor, Barbara Malinowska
BACKGROUND AND PURPOSE: Fatty acid amide hydrolase (FAAH) inhibitors are postulated to possess anti-hypertensive potential, because their acute injection decreases blood pressure (BP) in spontaneously hypertensive rats (SHR) partially through normalization of cardiac contractile function. Here, we examined whether the potential hypotensive effect of chronic FAAH inhibition by URB597 in hypertensive rats correlates with changes in cardiac performance. EXPERIMENTAL APPROACH: Experiments were performed using perfused hearts and left atria isolated from 8-10 week old SHR, age-matched deoxycorticosterone acetate (DOCA-salt) rats and normotensive controls chronically treated with URB597 (1 mg kg(-1) ) or vehicle...
April 24, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28437856/microstructure-variations-in-the-soft-hard-tissue-junction-of-the-human-anterior-cruciate-ligament
#7
Lei Zhao, Peter V Lee, David C Ackland, Neil D Broom, Ashvin Thambyah
The role of the sub-bundles in the anterior cruciate ligament (ACL) has been defined, such that the anterior-medial bundle directly resists anterior tibial translation while the posterior lateral bundle is involved in rotational stability. With regards to this biomechanical function, much of the previous work on bundle-specific morphology has been carried out on the macro-scale, with much less attention given to the micro-to-ultrastructural scalar levels. This is especially true of the enthesis and its microstructure, a biomechanically significant region that has been largely neglected in the published literature dealing with ACL sub-bundle anatomy...
April 24, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28437850/public-perception-of-uncertainties-within-climate-change-science
#8
Vivianne H M Visschers
Climate change is a complex, multifaceted problem involving various interacting systems and actors. Therefore, the intensities, locations, and timeframes of the consequences of climate change are hard to predict and cause uncertainties. Relatively little is known about how the public perceives this scientific uncertainty and how this relates to their concern about climate change. In this article, an online survey among 306 Swiss people is reported that investigated whether people differentiate between different types of uncertainty in climate change research...
April 24, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28437820/-therapy-of-hemifacial-spasm-with-botulinum-toxin
#9
Wolfgang H Jost, Rainer Laskawi, Anja Palmowski-Wolfe, Peter P Urban
Hemifacial spasm (HFS) is a frequent disorder characterized by involuntary contractions of those muscles innervated by the facialis nerve on one side of the face. The symptoms can appear as tonic or clonic, intermittent or permanent. Diagnosis is based purely on clinical observation. Differential diagnosis should rely on cranial MRI, which can demonstrate a pathological contact between the nerves and vessels and exclude alternative causation. Often, the symptoms are not marked so that therapy may not be necessary...
April 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/28437815/-cancer-related-fatigue-in-rehabilitation-care
#10
Susanne Kuhnt, Carina Szalai, Bianca Erdmann-Reusch, Conrad Kubel, Anna Boehncke, Wilfried Hoffmann, Anja Mehnert, Joachim Weis
Aim of the study was to provide information about the prevalence of cancer related fatigue and the association between treatment-related factors and fatigue in cancer patients during the rehabilitation care. In a multicenter study 693 cancer patients (27% breast cancer, 17% prostate cancer etc.) completed the Multidimensional Fatigue Inventory (MFI-20) and sociodemographic and treatment information was noted. 51% of the patients suffer from fatigue (n=356). Fatigue prevalence differed according to tumour localization (p≤0...
April 24, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28437813/presenting-symptoms-of-pituitary-apoplexy
#11
Efstratios-Stylianos Pyrgelis, Ioannis Mavridis, Maria Meliou
The classical term "pituitary apoplexy" (PA) describes a clinical syndrome usually characterized by abrupt onset of headache accompanied by neurologic and/or endocrinologic deterioration due to sudden expansion of a mass within the sella turcica as a result of hemorrhage or infarction within a pituitary tumor and adjacent pituitary gland. PA is a medical emergency and a difficult diagnosis to establish. Thus this article reviews the presenting symptoms of PA patients to help clinicians recognize or at least suspect this critical condition early on...
April 24, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28437789/comparative-proteomics-uncovers-correlated-signaling-network-and-potential-biomarkers-for-progression-of-prostate-cancer
#12
Jianzhong Ai, Yi Lu, Qiang Wei, Hong Li
BACKGROUND/AIMS: Prostate cancer is one of the most common cancers for males worldwide, and it is prone to show the metastatic foci in lymph node and bone with high mortality. To date, the potential mechanism and the corresponding biomarkers for metastatic prostate cancer are still lacking. Hence, our study aims to clarify the mechanism of prostate cancer progression and identify the useful biomarkers for metastatic prostate cancer. METHODS: The proteins and network tightly associated with tumor metastasis were identified using quantitative proteomics...
January 10, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28437782/detection-of-renal-hypoxia-in-lupus-nephritis-using-blood-oxygen-level-dependent-mr-imaging-a-multiple-correspondence-analysis
#13
Huilan Shi, Tiekun Yan, Dong Li, Junya Jia, Wenya Shang, Li Wei, Zhenfeng Zheng
BACKGROUND/AIMS: Nephrologists have pursued ideal, dynamic and noninvasive methods for assessing renal function and disease progression. Blood oxygen level dependent (BOLD) imaging is a useful technique for assessing renal disease. This current study was performed to explore the correlation between the hypoxia iconographical index and renal pathological features in lupus nephritis. METHODS: Adult patients with lupus nephritis (LN) and healthy volunteers were recruited for this study...
April 5, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28437761/negative-appraisals-and-fear-extinction-are-independently-related-to-ptsd-symptoms
#14
Daniel V Zuj, Matthew A Palmer, Kate E Gray, Chia-Ming K Hsu, Emma L Nicholson, Gin S Malhi, Richard A Bryant, Kim L Felmingham
BACKGROUND: Considerable research has revealed impaired fear extinction to be a significant predictor of PTSD. Fear extinction is also considered the primary mechanism of exposure therapy, and a critical factor in PTSD recovery. The cognitive theory of PTSD proposes that symptoms persist due to excessive negative appraisals about the trauma and its sequelae. Research has not yet examined the relationship between fear extinction and negative appraisals in PTSD. METHODS: A cross-sectional sample of participants with PTSD (n =21), and trauma-exposed controls (n =33) underwent a standardized differential fear conditioning and extinction paradigm, with skin conductance response (SCR) amplitude serving as the index of conditioned responses...
April 17, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28437736/murine-diet-induced-obesity-remodels-cardiac-and-liver-mitochondrial-phospholipid-acyl-chains-with-differential-effects-on-respiratory-enzyme-activity
#15
E Madison Sullivan, Amy Fix, Miranda J Crouch, Genevieve C Sparagna, Tonya N Zeczycki, David A Brown, Saame Raza Shaikh
Cardiac phospholipids, notably cardiolipin, undergo acyl chain remodeling and/or loss of content in aging and cardiovascular diseases, which is postulated to mechanistically impair mitochondrial function. Less is known about how diet-induced obesity influences cardiac phospholipid acyl chain composition and thus mitochondrial responses. Here we first tested if a high fat diet remodeled murine cardiac mitochondrial phospholipid acyl chain composition and consequently disrupted membrane packing, supercomplex formation and respiratory enzyme activity...
April 12, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28437731/children-and-adolescents-facing-a-continuous-security-threat-aggressive-behavior-and-post-traumatic-stress-symptoms
#16
Orit Nuttman-Shwartz
There is extensive research evidence indicating that children and youth are the most vulnerable population for developing psychological symptoms relating to war and terror. Although studies have documented a wide range of detrimental emotional and behavioral effects of such exposure, much less is known about the effects of exposure to a continuous security threat for children and adolescents. Against this background, the current article examined the implications of continuous exposure to missile attacks among 1096 children and adolescents enrolled in public schools near the Israeli border with Gaza...
April 21, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28437729/evaluation-of-the-effects-of-polymeric-chitosan-tripolyphosphate-and-solid-lipid-nanoparticles-on-germination-of-zea-mays-brassica-rapa-and-pisum-sativum
#17
Daniele Y Nakasato, Anderson E S Pereira, Jhones L Oliveira, Halley C Oliveira, Leonardo F Fraceto
Although the potential toxicity of many metallic and carbon nanoparticles to plants has been reported, few studies have evaluated the phytotoxic effects of polymeric and solid lipid nanoparticles. The present work described the preparation and characterization of chitosan/tripolyphosphate (CS/TPP) nanoparticles and solid lipid nanoparticles (SLN) and evaluated the effects of different concentrations of these nanoparticles on germination of Zea mays, Brassica rapa, and Pisum sativum. CS/TPP nanoparticles presented an average size of 233...
April 21, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28437727/new-inter-correlated-genes-targeted-by-diatom-derived-polyunsaturated-aldehydes-in-the-sea-urchin-paracentrotus-lividus
#18
Nadia Ruocco, Anna Maria Fedele, Susan Costantini, Giovanna Romano, Adrianna Ianora, Maria Costantini
The marine environment is continually subjected to the action of stressors (including natural toxins), which represent a constant danger for benthic communities. In the present work using network analysis we identified ten genes on the basis of associated functions (FOXA, FoxG, GFI-1, nodal, JNK, OneCut/Hnf6, TAK1, tcf4, TCF7, VEGF) in the sea urchin Paracentrotus lividus, having key roles in different processes, such as embryonic development and asymmetry, cell fate specification, cell differentiation and morphogenesis, and skeletogenesis...
April 21, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28437722/effective-active-vaccination-against-methamphetamine-in-female-rats
#19
J D Nguyen, P T Bremer, C S Hwang, S A Vandewater, K C Collins, K M Creehan, K D Janda, M A Taffe
BACKGROUND: Immunotherapies directed against methamphetamine (MA) abuse have shown success in rodent models, however only a limited number of studies have investigated active vaccination in female mice and none in female rats. It is critical to determine if potential immunotherapeutic strategies generalize across sex, particularly for drugs that may produce significant sex-differences on behavioral or physiological endpoints. METHODS: Female Wistar rats were initially vaccinated with keyhole-limpet hemocyanin (KLH) or an anti-methamphetamine-KLH conjugate (MH6-KLH) three times over five weeks and implanted with radiotelemetry devices to assess locomotor activity and body temperature responses to MA...
April 14, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28437718/nontargeted-metabolomics-approach-for-the-differentiation-of-cultivation-ages-of-mountain-cultivated-ginseng-leaves-using-uhplc-qtof-ms
#20
Xiangwei Chang, Juanjuan Zhang, Dekun Li, Dazheng Zhou, Yuling Zhang, Jincheng Wang, Bing Hu, Aichun Ju, Zhengliang Ye
The adulteration or falsification of the cultivation age of mountain cultivated ginseng (MCG) has been a serious problem in the commercial MCG market. To develop an efficient discrimination tool for the cultivation age and to explore potential age-dependent markers, an optimized ultra high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UHPLC/QTOF-MS)-based metabolomics approach was applied in the global metabolite profiling of 156 MCG leaf (MGL) samples aged from 6 to 18 years...
April 13, 2017: Journal of Pharmaceutical and Biomedical Analysis
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