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Ayako Okada, Morio Shoda, Hiroaki Tabata, Wataru Shoin, Hideki Kobayashi, Takahiro Okano, Koji Yoshie, Yasutaka Oguchi, Takahiro Takeuchi, Ken Kato, Koichiro Kuwahara
BACKGROUND: The estimated incidence of infected cardiac implantable electric devices (CIED) has recently increased to 1-2% in Japan. Extraction of long-term implanted devices is generally difficult. There are few reports about lead extraction in Japan. We describe our experience with and outcomes of lead extraction using excimer lasers, mechanical sheaths, and manual extraction. METHODS: We retrospectively analyzed the characteristics, types of devices, and indications for extraction in 29 patients with 67 leads who required CIED lead extraction at Shinshu University Hospital between April 2014 and October 2016...
September 13, 2017: Journal of Cardiology
Maryam Mahmood, Ayse Tuba Kendi, Saira Farid, Saira Ajmal, Geoffrey B Johnson, Larry M Baddour, Panithaya Chareonthaitawee, Paul A Friedman, M Rizwan Sohail
OBJECTIVE: We performed a meta-analysis evaluating the use of fluorine-18-fluorodeoxyglucose ((18)F-FDG) positron-emission tomography (PET)/computed tomography (CT) in the diagnosis of cardiovascular implantable electronic device (CIED) infections. BACKGROUND: PET/CT may be helpful in the diagnosis of CIED infection, particularly in patients with the absence of localizing signs or definitive echocardiographic findings. METHODS: PubMed, Embase, Cochrane library, CINAHL, Web of Knowledge, and www...
September 14, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Ahad Ollah Ezzati, Matthew T Studenski
PURPOSE: To quantify the relative neutron damage induced in CIEDs from clinical 18 MV photon beams for varying field sizes, depths and off axis distances. METHODS AND MATERIALS: Damage was assessed using silicon damage response functions and ICRP neutron dose conversion factors in MCNPX. Particular attention was devoted to the modelling of the Varian 2100C/D linear accelerator to ensure accurate contamination neutron spectra. Neutron dose, fluence and relative damage to CIEDs was calculated...
September 14, 2017: Medical Physics
Giovanna Parisi, Marco Colella, Serena Monticelli, Giuseppe Romanazzi, Wolfgang Holzer, Thierry Langer, Leonardo Degennaro, Vittorio Pace, Renzo Luisi
The first direct and straightforward nucleophilic fluoromethylation of organic compounds is reported. The tactic employs a "fleeting" lithium fluorocarbenoid (LiCH2F) generated from commercially available fluoroiodomethane. Precise reaction conditions were devel-oped for generation and synthetic exploitation of such a labile spe-cies. The versatility of the strategy is showcased in about 50 examples involving a plethora of electrophiles. Highly valuable chemicals such as fluoro alcohols, fluoro amines and fluoromethylated oxy-genated heterocycles could be prepared in very good yields through a single synthetic operation...
September 11, 2017: Journal of the American Chemical Society
William Tchabo, Yongkun Ma, Emmanuel Kwaw, Haining Zhang, Lulu Xiao, Maurice T Apaliya
The four different methods of color measurement of wine proposed by Boulton, Giusti, Glories and Commission International de l'Eclairage (CIE) were applied to assess the statistical relationship between the phytochemical profile and chromatic characteristics of sulfur dioxide-free mulberry (Morus nigra) wine submitted to non-thermal maturation processes. The alteration in chromatic properties and phenolic composition of non-thermal aged mulberry wine were examined, aided by the used of Pearson correlation, cluster and principal component analysis...
January 15, 2018: Food Chemistry
Wei-Lin Wan, Yu-Jung Lin, Hsin-Lung Chen, Chieh-Cheng Huang, Po-Chien Shih, Yu-Ru Bow, Wei-Tso Chia, Hsing-Wen Sung
Hydrogen (H2) gas can reduce cytotoxic reactive oxygen spe-cies (ROS) that are produced in inflamed tissues. Inspired by natural photosynthesis, this work proposes a multicomponent nanoreactor (NR) that comprises chlorophyll a, L-ascorbic acid, and gold nanoparticles that are encapsulated in a liposomal (Lip) system that can produce H2 gas in situ upon photon absorption to mitigate inflammatory responses. Unlike a bulk system that contains free reacting molecules, this Lip NR system provides an optimal reaction environment, facilitating rapid activation of the photosynthesis of H2 gas, locally providing a high therapeu-tic concentration thereof...
September 5, 2017: Journal of the American Chemical Society
Srinivasan Natarajan, Jagannatha Gopalakrishnan, Sourav Laha, Anupam Bhim
We have explored garnet structured oxide materials containing 3d-transition metal ions (Co2+, Ni2+, Cu2+, Fe3+) for the development of new inorganic colored materials. For this purpose, we have synthesized new garnets, Ca3Sb2Ga2ZnO12 (I) and Ca3Sb2Fe2ZnO12 (II), that are isostructural with Ca3Te2Zn3O12. Substitution of Co2+, Ni2+, Cu2+ at the tetrahedral Zn2+ sites in (I) and (II) gives rise to brilliantly colored materials (different shades of blue, green, turquoise and red). The materials are characterized by optical absorption spectral study and CIE chromaticity diagrams...
September 4, 2017: Chemistry, An Asian Journal
Kelsy R Steele, Loretta Szczotka-Flynn
Corneal infiltrative events (CIEs) are well established as a risk associated with soft contact lens wear. The incidence of symptomatic CIEs during extended soft lens wear ranges from 2.5 to six per cent; when asymptomatic CIEs are included, the incidence can be as high as 20-25 per cent. In daily soft lens wear, the annual incidence of symptomatic CIEs is about three per cent. There are various accepted methods of categorising CIEs, and a scoring system based on clinical signs and symptoms is a good approach to grade severity...
September 4, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Sijia Sun, Hao Ding, Hong Zhou
We obtained hydrophobic barite (BaSO4) and rutile titanium dioxide (TiO2) particles (as raw materials) by organic surface modification. Subsequently, TiO2-coated barite composite pigments were prepared via the hydrophobic aggregation of heterogeneous particles in a water medium. The pigment properties of the TiO2-coated barite composite pigments were characterized and evaluated by determining their hiding power, oil absorption value and whiteness. The optical properties were determined by obtaining their UV-vis diffuse reflectance spectra and using the CIE-L*a*b* method...
August 30, 2017: Scientific Reports
Daniel C DeSimone, Anwar A Chahal, Christopher V DeSimone, Samuel J Asirvatham, Paul A Friedman, Larry M Baddour, M Rizwan Sohail
BACKGROUND: Cardiovascular implantable electronic devices (CIEDs) can be life-saving. However, complications from CIED infection can be life-threatening often requiring device removal. Despite publication of CIED infection management guidelines there remains marked variation in clinical practice. OBJECTIVE: To better understand and quantify these differences, we conducted a multi-national survey of practitioners of CIED management. METHODS: An electronic survey was sent to Heart Rhythm Society members, spanning 70 countries across six continents...
August 28, 2017: Pacing and Clinical Electrophysiology: PACE
Eugene M Tan, Avish Nagpal, Daniel C DeSimone, Brenda Anderson, Jane Linderbaum, Thomas De Ziel, Zhuo Li, Muhammad R Sohail, Yong-Mei Cha, Erica Loomis, Raul Espinosa, Paul A Friedman, Kevin Greason, Henry Schiller, Abinash Virk, Walter R Wilson, James M Steckelberg, Larry M Baddour
PURPOSE: Cardiovascular implantable electronic device infection (CIEDI) rates are rising. To improve outcomes, our institution developed an online care process model (CPM) and a specialized inpatient heart rhythm service (HRS). METHODS: This retrospective review compared hospital length of stay (LOS), mortality, and times to subspecialty consultation and procedures before and after CPM and HRS availability. RESULTS: CPM use was associated with shortened time to surgical consultation (median 2 days post-CPM vs...
August 26, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Hua He, Bing-Bing Ke, Yan Li, Fu-Sheng Han, Xiaodong Li, Yu-Jie Zeng
PURPOSE: Network meta-analysis (NMA) has advantages including being able to simultaneously compare and rank multiple treatments over traditional meta-analysis. We evaluated by a NMA the optimal antithrombotic strategy during the perioperative period of implantation of cardiovascular implantable electronic devices (CIEDs). METHODS: We performed a network meta-analysis of observational studies (cohort and case-control studies). The eligible studies tested the following antithrombotic therapy during the CIED placement: aspirin, clopidogrel, warfarin, novel oral anticoagulants (NOACs), and heparin bridging...
August 25, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Jürg Schläpfer, Hein J Wellens
Computerized interpretation of the electrocardiogram (CIE) was introduced to improve the correct interpretation of the electrocardiogram (ECG), facilitating health care decision making and reducing costs. Worldwide, millions of ECGs are recorded annually, with the majority automatically analyzed, followed by an immediate interpretation. Limitations in the diagnostic accuracy of CIE were soon recognized and still persist, despite ongoing improvement in ECG algorithms. Unfortunately, inexperienced physicians ordering the ECG may fail to recognize interpretation mistakes and accept the automated diagnosis without criticism...
August 29, 2017: Journal of the American College of Cardiology
Rajamouli Boddula, Kasturi Singh, Santanab Giri, Sivakumar Vaidyanathan
A new diphenylamine-functionalized ancillary-ligand-coordinated europium(III) β-diketonate complex showed incomplete photoexcitation energy transfer from a ligand to a Eu(III) ion. A solvatochromism study led to a balancing of the primary colors to obtain single-molecule white-light emission. Thermal-sensing analysis of the europium complex was executed. The europium complex, conjugated with a near-UV-light-emitting diode (395 nm), showed appropriate white-light-emission CIE color coordinates (x = 0.34 and y = 0...
August 24, 2017: Inorganic Chemistry
Mariana S Parahuleva, Nedim Soydan, Dimitar Divchev, Ulrich Lüsebrink, Bernhard Schieffer, Ali Erdogan
BACKGROUND: The Home Monitoring (HM) system of cardiac implantable electronic devices (CIEDs) permits early detection of arrhythmias or device system failures. The aim of this pilot study was to examine how the safety and efficacy of the HM system in patients after ambulatory implanted primary CIEDs compare to patients with a standard procedure and hospitalization. HYPOTHESIS: We hypothesized that HM and their modifications would be a useful extension of the present concepts for ambulatory implanted CIEDs...
August 21, 2017: Clinical Cardiology
Adam Kimbrough, Giordano de Guglielmo, Jenni Kononoff, Marsida Kallupi, Eric P Zorrilla, Olivier George
BACKGROUND: In humans, emotional and physical signs of withdrawal from ethanol are commonly seen. Many of these symptoms, including anxiety-like and depression-like behavior, have been characterized in animal models of ethanol dependence. One issue with several current behavioral tests that measure withdrawal in animal models is they are often not repeatable within subjects over time. Additionally, irritability, one of the most common symptoms of ethanol withdrawal in humans, has not been well characterized in animal models...
August 23, 2017: Alcoholism, Clinical and Experimental Research
Karin Rybak
Telemonitoring (TM) features are implemented in nearly all cardiac implantable electronic devices (CIEDs) that have recently been released to the market. In combination with pacemakers, defibrillators and systems for cardiac resynchronization it is a safe and efficient method for routine technical aftercare of the devices as well as for monitoring heart failure and arrhythmias. Using TM has the potential to optimize patient care with regard to economic, clinical and safety aspects. Despite the good availability of existing data and clear recommendations of the responsible scientific societies, it is often seen as an isolated solution which is not fully integrated into standard care, although it has its own EBM number for implantable cardioverter-defibrillators and cardiac resynchronization therapy systems...
August 22, 2017: Herzschrittmachertherapie & Elektrophysiologie
Sean D Pokorney, Xiaojuan Mi, Robert K Lewis, Melissa Greiner, Laurence M Epstein, Roger G Carrillo, Emily P Zeitler, Sana M Al-Khatib, Donald D Hegland, Jonathan P Piccini
Background -Lead management is an increasingly important aspect of care in patients with cardiac implantable electronic devices (CIED); however, relatively little is known about long-term outcomes after capping and abandoning leads. Methods -Using the 5% Medicare sample, we identified patients with (1) de novo CIED implants between 1/1/2000 and 12/31/2013 and (2) a subsequent lead addition or extraction ≥12 months after the de novo implant. Patients who underwent extraction for infection were excluded. Using multivariable Cox proportional hazards models, cumulative incidence of all-cause mortality, device-related infection, device revision, and lead extraction at 1 and 5 years were compared for the extract versus the cap and abandon groups...
August 22, 2017: Circulation
Pin-Chun Lin, Kuei-Ting Hsu, Ming-Hsiu Shiu, Wei-Ren Liu
To facilitate the next generation of environmental material for white light emitting diodes, the discovery of natural luminesce is essential. In this study, we disclose a rare-earth free and yellow-emission phosphor, Phellodendron, which could be both excited by near ultraviolet light and blue light. The new yellow phosphor is obtained by extraction of Phellodendron chinense Schneid. The emission wavelength, full width at half maximum and CIE coordinates of extracted Phellodendron are 540 nm, 120 nm and (0...
August 21, 2017: Scientific Reports
Westyn Branch-Elliman
PURPOSE OF REVIEW: Cardiovascular implantable electronic device (CIED) infections are highly morbid, common, and costly, and rates are increasing (Sohail et al. Arch Intern Med 171(20):1821-8 2011; Voigt et al. J Am Coll Cardiol 48(3):590-1 2006). Factors that contribute to the development of CIED infections include patient factors (comorbid conditions, self-care, microbiome), procedural details (repeat procedure, contamination during procedure, appropriate pre-procedural prep, and antimicrobial use), environmental and organizational factors (patient safety culture, facility barriers, such as lack of space to store essential supplies, quality of environmental cleaning), and microbial factors (type of organism, virulence of organism)...
August 16, 2017: Current Infectious Disease Reports
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