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Chao Fang, Ronghui Zheng, Yusheng Zhang, Fukun Hong, Jingli Mu, Mengyun Chen, Puqing Song, Longshan Lin, Heshan Lin, Fengfeng Le, Jun Bo
The seafloor is recognized as one of the major sinks for microplastics (MPs). However, to date there have been no studies reported the MP contamination in benthic organisms from the Arctic and sub-Arctic regions. Therefore, this study provided the first data on the abundances and characteristics of MPs in a total of 413 dominant benthic organisms representing 11 different species inhabiting in the shelf of Bering and Chukchi Seas. The mean abundances of MP uptake by the benthos from all sites ranged from 0...
June 14, 2018: Chemosphere
Aron H Blaesi, Nannaji Saka
Recently, we have introduced fibrous dosage forms prepared by 3D-micro-patterning of drug-laden viscous melts. Such dosage forms enable predictable microstructures and increased drug release rates, and they can be manufactured continuously. However, melt processing is not applicable if the melting temperature of the formulation is greater than the degradation temperature of the drug or of the excipient. In this work, therefore, a continuous wet micro-patterning process that operates at ambient temperature is presented...
June 19, 2018: European Journal of Pharmaceutics and Biopharmaceutics
Justin DiSanti, Caroline Lisee, Karl Erickson, David Bell, Michael Shingles, Christopher Kuenze
Study Design Phenomenographic, cross-sectional. Background Adolescent athletes struggle to return to sport (RTS) following ACL reconstruction (ACLR) for a number of physical and psychosocial reasons. The ability to incorporate contextual evidence obtained directly from patients with the growing body of quantitative rehabilitation research may aid clinicians in taking an evidence-based approach to rehabilitation and return to sports within the adolescent population.. Objectives To assess perceived barriers to RTS as well as positive and negative factors influencing recovery among high school athletes with recent history of ACLR...
June 22, 2018: Journal of Orthopaedic and Sports Physical Therapy
Michael Habs, Karin Binder, Stefan Krauss, Karolina Müller, Brigitte Ernst, Luzia Valentini, Michael Koller
OBJECTIVES: Pyrrolizidine alkaloids (PA) exist ubiquitously in our environment. More than 6000 plants, about 3% of the world’s flowering plants, are known to synthesize PA. As a consequence, many herbal ingredients, including St. John’s wort (SJW), are contaminated with PA that can possess acute and subchronic toxic effects as well as mutagenic and genotoxic properties. Therefore, the possible benefits of SJW as an herbal remedy against depression need to be weighed against the possible risks of unwanted PA intake...
June 22, 2018: Nutrients
G D Raby, J Sundin, F Jutfelt, S J Cooke, T D Clark
Adult bluespotted rockcod Cephalopholis cyanostigma, a coral-reef grouper, were acclimated to either ambient (mean ± S.D. 41.12 ± 2.13 Pa;) or high pCO2 (95.75 ± 11.75 Pa) conditions in a laboratory for 8-9 days, then released at the water surface directly above a reef (depth c. 5 m) and followed on video camera (for 191 ± 21 s) by scuba divers until they sought cover in the reef. No differences were detected between groups in any of the six measured variables, which included the time fish spent immobile after release, tail beat frequency during swimming and the time required to locate and enter the protective shelter of the reef...
June 21, 2018: Journal of Fish Biology
Satomi Kasashima, Atsuhiro Kawashima, Fuminori Kasashima, Masamitsu Endo, Yasushi Matsumoto, Kengo Kawakami
Immunoglobulin (IgG) 4-related diseases (IgG4-RDs) are fibro-inflammatory conditions characterized by tumorous swelling and serum IgG4 levels. Intrapelvic IgG4-RD has been subclassified according to the localization site and aortic shape as IgG4-related aortic aneurysms (IgG4-AAs), periaortitis (IgG4-PA), and retroperitoneal fibrosis (IgG4-RF). The IgG4-AA pathogenesis would involve interleukin (IL)-6 upregulation, and Th2-predominant and Treg-activated immune conditions. We characterized the features of intrapelvic IgG4-RD lesions, including presence of vascular lesions...
June 21, 2018: Heart and Vessels
Masayuki Takahashi, Hisashi Yokoshiki, Hirofumi Mitsuyama, Taro Tenma, Masaya Watanabe, Rui Kamada, Ryo Sasaki, Yuki Chiba, Motoki Maeno, Toshihisa Anzai
Prolongation of the pulmonary artery potentials (PAPs) in response to short coupling intervals was related to polymorphic QRS configurations during the ventricular tachycardia originating above the pulmonary valve (PA-VT). This prospective study was aimed to investigate the mechanisms of polymorphic changes during the PA-VT. We performed the mapping above the pulmonary valve using a 20-polar circumferential catheter and three-dimensional integrated intracardiac echocardiography in 9 consecutive patients with outflow tract arrhythmias undergoing catheter ablation (UMIN ID: UMIN000021682)...
June 21, 2018: Heart and Vessels
Sheri A Rowland, Kris E Berg, Kevin A Kupzyk, Carol H Pullen, Marlene Z Cohen, Paula S Schulz, Bernice C Yates
Most working women do not meet current guidelines for physical activity (PA). A 12-week pilot study tested a workplace, peer modeling PA intervention. Inactive female employees from a health system were randomized to an attention control group (ACG; n = 26) or an intervention group (IG; n = 26). The ACG received health information. The IG participated in six group sessions with an active peer model and received an exercise prescription and PA information. Pre and post measures were PA (ActiGraph), Estimated VO2max (cycle ergometer), resting heart rate (HR), glucose and lipids, and cardiovascular risk...
June 1, 2018: Workplace Health & Safety
Jian Zeng, Min Chen, Minfang Zheng, Yusheng Qiu, Wentao He, Yingxue He, Xiao Liu
Although the influence of suspended particulate matter (SPM) on denitrifying activity has been identified in river waters recently through metabolic incubations and community gene analysis, the regulations of SPM to denitrification in marine systems are still poorly understood. In the present study, the effects of suspended particle properties (including concentration, composition and size) on potential denitrification were explored in the coastal Beibu Gulf water columns based on a series of 15 N-labeled incubations under artificial anaerobic condition...
May 15, 2018: Science of the Total Environment
Pengcheng Peng, Hui Huang, Hongqiang Ren, Haijun Ma, Yuan Lin, Jinju Geng, Ke Xu, Yan Zhang, Lili Ding
Startup of biofilm process triggered by initial adhesion of bacteria is difficult in high ammonia nitrogen wastewater treatment. In this study, the influence of two commonly used N-acyl homoserine lactones (AHLs), N-Hexanoyl-l-homoserine lactone (C6-HSL) and N-Octanoyl-l-homoserine lactone (C8-HSL), on the adhesion of soluble macromolecules and bacteria in four types of high ammonia nitrogen wastewater to surfaces of model biocarriers (i.e. polystyrene, polyamide and polyethylene terephthalate) was investigated by using a quartz crystal microbalance with dissipation (QCM-D) monitoring technology...
May 15, 2018: Science of the Total Environment
Pau Comajoan, Carme Gubern, Gemma Huguet, Joaquín Serena, Elisabet Kádár, Mar Castellanos
Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is the only pharmacological approved treatment for ischemic stroke, despite its associated increasing risk of hemorrhagic transformation. Since many of rt-PA effects in blood-brain barrier (BBB) are not well characterized, the study of protein changes in BBB cells after rt-PA administration may help to understand its adverse effects. Our aim was to analyze protein levels of four commonly used housekeeping proteins: β-Actin, α-Tubulin, GAPDH and HPRT in bEnd...
June 18, 2018: Journal of Proteomics
Binglin Li, Dandan Duan, Jiao Wang, Huanyu Li, Xiaoli Zhang, Binxia Zhao
Phospholipase D (PLD) was firstly hyperactivated by the bio-imprinting and, then, these hyperactivated PLD molecules were immobilized by adsorption and precipitation, followed by cross-linking. The high degree of conformational rigidification provided by intra- and intermolecular cross-linking can make PLD "remember" imprint-induced characteristics even in aqueous solutions. The obtained immobilized PLD showed the excellent catalytic performance. The maximum activity of immobilized PLD reached 166953 U/gprotein , which was approximately 14 times higher than that of free form (11922 U/gprotein )...
June 18, 2018: Journal of Biotechnology
Wei Zhang, Sirong He, Yao Cheng, Jie Xia, Mingliang Lai, Nansheng Cheng, Zuojin Liu
BACKGROUND: The use of surgical drains has been considered mandatory after pancreatic surgery. The role of prophylactic abdominal drainage to reduce postoperative complications after pancreatic surgery is controversial. OBJECTIVES: To assess the benefits and harms of routine abdominal drainage after pancreatic surgery, compare the effects of different types of surgical drains, and evaluate the optimal time for drain removal. SEARCH METHODS: For the last version of this review, we searched CENTRAL (2016, Issue 8), and MEDLINE, Embase, Science Citation Index Expanded, and Chinese Biomedical Literature Database (CBM) to 28 August 2016)...
June 21, 2018: Cochrane Database of Systematic Reviews
Dongmiao Chen, Yajie Zhang, Yinjuan Xu, Tingting Shen, Guorui Cheng, Bingkang Huang, Xiandong Ruan, Congrong Wang
Objective: This study aimed to compare the performance of chemiluminescence immunoassay (CLIA), enzyme-linked immunosorbent assay (ELISA), and passive agglutination (PA) method in detecting Mycoplasma pneumoniae (MP) infection. Methods: This study enrolled a total of 280 patients who were consecutively seen at the Nanfang Hospital of the Southern Medical University in Guangdong Province, China, between August and December 2016. Serum was collected and examined by CLIA, ELISA, and PA, respectively...
2018: Therapeutics and Clinical Risk Management
Kowsar Bavarsad, Mousa-Al-Reza Hadjzadeh, Mahmoud Hosseini, Roghayeh Pakdel, Farimah Beheshti, Soleyman Bafadam, Zeinab Ashaari
The effect of levothyroxine (L-T4) on the learning and memory impairment induced by streptozotocin (STZ) and brain tissue oxidative damage in rats was evaluated. An animal model of the Alzheimer's disease (AD) was established by intracerebroventricular injection of STZ (3 mg/kg) in male Wistar rats (250 ± 50 g). After that, the rats were treated for 3 weeks with L-T4 (10, 100 μg/kg) or normal saline. Passive avoidance (PA) learning and spatial memory were evaluated using shuttle box and Morris water maze (MWM), respectively...
June 21, 2018: Drug and Chemical Toxicology
Tracey Covassin, Kyle M Petit, Jennifer L Savage, Abigail C Bretzin, Meghan E Fox, Lauren F Walker, Daniel Gould
BACKGROUND: Sports-related concussion (SRC) injury rates, and identifying those athletes at the highest risk, have been a primary research focus. However, no studies have evaluated at which time point during an athletic event athletes are most susceptible to SRCs. PURPOSE: To determine the clinical incidence of SRCs during the start, middle, and end of practice and competition among high school male and female athletes in the state of Michigan. STUDY DESIGN: Descriptive epidemiological study...
June 1, 2018: American Journal of Sports Medicine
David Herrera, Belén Retamal-Valdes, Bettina Alonso, Magda Feres
OBJECTIVE: To critically evaluate the existing literature on acute lesions occurring in the periodontium (periodontal abscesses [PA], necrotizing periodontal diseases [NPD], and endo-periodontal lesions [EPL]) to determine the weight of evidence for the existence of specific clinical conditions that may be grouped together according to common features. The ultimate goal is to support an objective classification system. IMPORTANCE: Although PA, NPD, and EPL occur with relatively low frequency, these lesions are of clinical relevance, because they require immediate management and might severely compromise the prognosis of the tooth...
June 2018: Journal of Periodontology
Xinya Jiang, Huijun Wang, Ruo Yuan, Yaqin Chai
Reliable and sensitive in situ detection of molecule released from live cells attracts tremendous research interests as it shows significance in pathological and physiological investigation. In present work, a novel N-(aminobutyl)-N- (ethylisoluminol) functionalized Ag nanoparticles modified three dimensional (3D) polyaniline-phytic acid conducting hydrogels (ABEI-Ag@PAni-PA) are synthesized to adhere cells for in situ sensitive electrochemiluminescence (ECL) detection of hydrogen peroxide (H2O2) released from live cells...
June 21, 2018: Analytical Chemistry
David Herrera, Belén Retamal-Valdes, Bettina Alonso, Magda Feres
OBJECTIVE: To critically evaluate the existing literature on acute lesions occurring in the periodontium (periodontal abscesses [PA], necrotizing periodontal diseases [NPD], and endo-periodontal lesions [EPL]) to determine the weight of evidence for the existence of specific clinical conditions that may be grouped together according to common features. The ultimate goal is to support an objective classification system. IMPORTANCE: Although PA, NPD, and EPL occur with relatively low frequency, these lesions are of clinical relevance, because they require immediate management and might severely compromise the prognosis of the tooth...
June 2018: Journal of Clinical Periodontology
Iris Schaub, Christel Baum, Rhena Schumann, Ulf Karsten
Early successional biological soil crusts (BSCs), a consortium of bacteria, cyanobacteria, and other microalgae, are one of the first settlement stages on temperate coastal sand dunes. In this study, we investigated the algal biomass (Chlorophyll a (Chl a)), algal (Calgal ) and microbial carbon (Cmic ), elemental stoichiometry (C:N:P), and acid and alkaline phosphatase activity (AcidPA and AlkPA) of two algae-dominated BSCs from a coastal white dune (northeast Germany, on the southwestern Baltic Sea) which differed in the exposure to wind forces...
June 20, 2018: Microbial Ecology
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