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Non-ionic contrast

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https://www.readbyqxmd.com/read/29352692/ckd-epi-versus-cockcroft-gault-formula-for-predicting-contrast-induced-nephropathy-following-percutaneous-coronary-intervention-in-patients-without-significant-renal-impairment
#1
Mário B G Nunes, Antônio C Filho, Valéria R C Alvares, Rafael Moreno, Edgar Lamas, Vitor Loures, Daniel Chamié, Alexandre Abizaid
INTRODUCTION: Individuals with glomerular filtration rate (GFR) ≥60 ml/min/1.73 m2 estimated by the Cockcroft-Gault formula (CG) who undergo percutaneous coronary intervention (PCI) frequently develop contrast-induced nephropathy (CIN). This study aimed to assess whether individuals with significant renal impairment assessed by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, but not by CG, more often develop CIN following PCI than those without renal impairment by either formula...
January 15, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29314826/influence-of-salt-on-supramolecular-oscillatory-structural-forces-and-stratification-in-micellar-freestanding-films
#2
Subinuer Yilixiati, Rabees Rafiq, Yiran Zhang, Vivek Sharma
Freestanding films of soft matter containing micelles, nanoparticles, polyelectrolyte-surfactant complexes, bilayers and smectic liquid crystals exhibit stratification. Stepwise thinning and coexisting thick-thin regions associated with drainage via stratification are attributed to the confinement-induced structuring and layering of supramolecular structures, that contribute supramolecular oscillatory structural forces. In freestanding micellar films, formed by a solution of an ionic surfactant above its critical micelle concentration, both interfacial adsorption and the micelle size and shape, are determined by the concentration of surfactant and of added electrolytes...
January 9, 2018: ACS Nano
https://www.readbyqxmd.com/read/29306703/trace-organic-contaminant-rejection-by-aquaporin-forward-osmosis-membrane-transport-mechanisms-and-membrane-stability
#3
Ming Xie, Wenhai Luo, Hao Guo, Long D Nghiem, Chuyang Y Tang, Stephen R Gray
We investigated transport mechanisms of trace organic contaminants (TrOCs) through aquaporin thin-film composite forward osmosis (FO) membrane, and membrane stability under extreme conditions with respect to TrOC rejections. Morphology and surface chemistry of the aquaporin membrane were characterised to identify the incorporation of aquaporin vesicles into membrane active layer. Pore hindrance model was used to estimate aquaporin membrane pore size as well as to describe TrOC transport. TrOC transport mechanisms were revealed by varying concentration and type of draw solutions...
December 28, 2017: Water Research
https://www.readbyqxmd.com/read/29303417/evaluation-of-detergent-free-and-detergent-based-methods-for-decellularization-of-murine-skin
#4
Ali Farrokhi, Mohammadreza Pakyari, Layla Nabai, Amir Pourghadiri, Ryan Hartwell, Reza B Jalili, Aziz Ghahary
Acute and chronic wounds contribute to increased morbidity and mortality in affected people and impose significant financial burdens on healthcare systems. For these challenging wounds, Acellular Dermal Matrices (ADMs) have been used as a biological wound coverage. Unlike engineered dermal matrices, ADMs are prepared through the removal of cells from skin, while preserving the extracellular matrix structure and function. In this study, our primary objective was to develop a detergent-free method of decellularization of the skin to mitigate chemical stress on matrix molecules...
January 5, 2018: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29277987/bioinspired-manganese-chelated-alginate-poly-dopamine-nanomaterials-for-efficient-in-vivo-t1%C3%A2-weighted-magnetic-resonance-imaging-mri
#5
Kefyalew Dagnew Addisu, Balkew Zewge Hailemeskel, Shewaye Lakew Mekuria, Abegaz Tizazu Andrgie, Yu-Chun Lin, Hsieh-Chih Tsai
Manganese-based nanomaterials are an emerging new class of magnetic resonance imaging (MRI) contrast agents (CAs) that provide impressive contrast abilities. MRI CAs that can respond to pathophysiological parameters like pH or redox potential are also highly demanded for MRI guided tumor diagnosis. Until now, synthesizing nanomaterials with good biocompatibility, physio-chemical stability, and good contrast effects remain challenging. This study investigated two new systems of calcium/manganese cations complexed with either alginate-polydopamine or alginate-dopamine nanogels (AlgPDA(Ca/Mn) NG or AlgDA (Ca/Mn) NG)...
December 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29260811/the-aggregation-of-an-alkyl-c60-derivative-as-a-function-of-concentration-temperature-and-solvent-type
#6
Martin J Hollamby, Catherine F Smith, Melanie M Britton, Ashleigh E Danks, Zoe Schnepp, Isabelle Grillo, Brian R Pauw, Akihiro Kishimura, Takashi Nakanishi
Contrast-variation small-angle neutron scattering (CV-SANS), small-angle X-ray scattering (SAXS), nuclear magnetic resonance (NMR) measurements of diffusion and isothermal titration calorimetry (ITC) are used to gain insight into the aggregation of an alkyl-C60 derivative, molecule 1, in n-hexane, n-decane and toluene as a function of concentration and temperature. Results point to an associative mechanism of aggregation similar to other commonly associating molecules, including non-ionic surfactants or asphaltenes in non-aqueous solvents...
December 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29220750/differential-sensitivity-of-light-harnessing-photosynthetic-events-in-wheat-and-sunflower-to-exogenously-applied-ionic-and-nanoparticulate-silver
#7
P Pardha-Saradhi, Nisha Shabnam, P Sharmila, Ashok K Ganguli, Hyunook Kim
Potential impacts of inevitable leaks of silver nanoparticles (AgNPs) into environment on human beings need attention. Owing to the vitality of photosynthesis in maintaining life and ecosystem functioning, impacts of exogenously applied nanoparticulate and Ag+ on photosystem (PS)II function, which governs overall photosynthesis, in wheat and sunflower were evaluated. PSII efficiency and related Chl a fluorescence kinetics of these two plants remained unaffected by AgNPs. However, Ag+ caused a significant decline in the PSII activity and related fluorescence steps in wheat, but not in sunflower...
November 22, 2017: Chemosphere
https://www.readbyqxmd.com/read/29215947/co-metabolic-degradation-of-iomeprol-by-a-pseudomonas-sp-and-its-application-in-biological-aerated-filter-systems
#8
Bingjie Xu, Bin Xu, Shiwei Shan, Gang Xue, Tianfeng Wang, Xiuwen Qiu, Changchao Zhan
The non-ionic water-soluble X-ray contrast agent iomeprol (IOM) enters the water supply through sewage treatment plants, which can cause considerable environmental harm. In this study, Pseudomonas sp. I-24 (I-24) was tested for its ability to remove IOM from water via co-metabolic pathways. The optimum removal rate of IOM by I-24 was 38.43% ± 3.70% when starch served as the source of external carbon, and its co-metabolism of IOM conformed to the first-order kinetics. The highest activity of intracellular enzyme (degrading enzyme) extracted from I-24 was 0...
December 7, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/29214792/life-threatening-thrombocytopenia-following-intravenous-contrast-media-infusion
#9
Mihwa Park, Minjeong Kim, Jisun Park, Jinhyun Cho
Radiocontrast media-induced acute severe thrombocytopenia is a very rare complication and potentially life-threatening. Here, we report the case of a 63-year-old male patient with severe acute thrombocytopenia following first exposure to intravenous non-ionic contrast media without immediate allergic reactions. His platelet count dropped from 107000/μL to 2000/μL after six hours of radiocontrast infusion. After administration of corticosteroid and transfusion of platelet concentrates, the platelet count returned gradually to normal within 5 days...
January 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29203375/free-energy-calculations-on-the-stability-of-the-14-3-3%C3%AE-protein
#10
Zuzana Jandova, Zuzana Trosanova, Veronika Weissova, Chris Oostenbrink, Jozef Hritz
Mutations of cysteine are often introduced to e.g. avoid formation of non-physiological inter-molecular disulfide bridges in in-vitro experiments, or to maintain specificity in labeling experiments. Alanine or serine is typically preferred, which usually do not alter the overall protein stability, when the original cysteine was surface exposed. However, selecting the optimal mutation for cysteines in the hydrophobic core of the protein is more challenging. In this work, the stability of selected Cys mutants of 14-3-3 ζ was predicted by free-energy calculations and the obtained data were compared with experimentally determined stabilities...
December 1, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29202235/tuning-of-nanoparticle-micelle-interactions-and-resultant-phase-behavior
#11
Debes Ray, Sugam Kumar, Vinod Kumar Aswal, Joachim Kohlbrecher
The evolution of the interaction between an anionic nanoparticle and a non-ionic surfactant and their resultant phase behavior in aqueous solution in the presence of electrolyte and ionic surfactants has been studied. The mixed system of anionic silica nanoparticles (Ludox LS30) with non-ionic surfactant decaethylene glycol monododecylether (C12E10) forms a highly stable clear phase over a wide concentration range of surfactant. Small-angle neutron scattering (SANS) and dynamic light scattering (DLS) data show that the surfactant micelles adsorb on the surface of the nanoparticle, resulting in the micellar-decorated nanoparticle structures...
December 4, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29165448/shedding-light-on-the-different-behavior-of-ionic-and-nonionic-surfactants-in-emulsion-polymerization-from-atomistic-simulations-to-experimental-observations
#12
Giulia Magi Meconi, Nicholas Ballard, José M Asua, Ronen Zangi
Although surfactants are known to play a vital role in polymerization reactions carried out in dispersed media, many aspects of their use are poorly understood, perhaps none more so than the vastly different action of ionic and nonionic surfactants in emulsion polymerization. In this work, we combine experimental measurements of emulsion polymerization of styrene with atomistic molecular dynamics simulations to better understand the behavior of surfactants at monomer/polymer-water interfaces. In a batch emulsion polymerization of styrene, the nonionic surfactant Disponil AFX 1080 leads to two nucleation periods, in contrast to the behavior observed for the ionic surfactant SDS...
November 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29159151/a-case-of-unusual-presentation-of-contrast-induced-encephalopathy-after-cerebral-angiography-using-iodixanol
#13
Jun Chul Park, Jun Hyong Ahn, In Bok Chang, Jae Keun Oh, Ji Hee Kim, Joon Ho Song
Contrast-induced encephalopathy after cerebral angiography is a rare complication and until now, only few cases have been reported. This paper reports on contras-induced encephalopathy mimicking meningoencephalitis after cerebral angiography by using iodixanol, an iso-osmolar non-ionic contrast agent. A 58-year-old woman underwent cerebral angiography for the evaluation of multiple intracranial aneurysms. A few hours later, she had persistent headache, vomiting, fever, and seizures. Brain computed tomography (CT) showed sulcal obliteration of right cerebral hemisphere and cerebrospinal fluid profile was unremarkable...
September 2017: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/29107695/contrast-enhanced-%C3%AE-ct-imaging-of-early-articular-changes-in-a-pre-clinical-model-of-osteoarthritis
#14
D S Reece, T Thote, A S P Lin, N J Willett, R E Guldberg
OBJECTIVE: The objective of this study was to characterize early osteoarthritis (OA) development in cartilage and bone tissues in the rat medial meniscus transection (MMT) model using non-destructive equilibrium partitioning of an ionic contrast agent micro-computed tomography (EPIC-μCT) imaging. Cartilage fibrillation, one of the first physiological developments in OA, was quantified in the rat tibial plateau as three-dimensional (3D) cartilage surface roughness using a custom surface-rendering algorithm...
October 28, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29049297/functional-connectivity-structure-of-cortical-calcium-dynamics-in-anesthetized-and-awake-mice
#15
Patrick W Wright, Lindsey M Brier, Adam Q Bauer, Grant A Baxter, Andrew W Kraft, Matthew D Reisman, Annie R Bice, Abraham Z Snyder, Jin-Moo Lee, Joseph P Culver
The interplay between hemodynamic-based markers of cortical activity (e.g. fMRI and optical intrinsic signal imaging), which are an indirect and relatively slow report of neural activity, and underlying synaptic electrical and metabolic activity through neurovascular coupling is a topic of ongoing research and debate. As application of resting state functional connectivity measures is extended further into topics such as brain development, aging and disease, the importance of understanding the fundamental physiological basis for functional connectivity will grow...
2017: PloS One
https://www.readbyqxmd.com/read/28948252/exploring-the-bulk-phase-structure-of-ionic-liquid-mixtures-using-small-angle-neutron-scattering
#16
Christopher P Cabry, Lucía D'Andrea, Karina Shimizu, Isabelle Grillo, Peixun Li, Sarah Rogers, Duncan W Bruce, José N Canongia Lopes, John M Slattery
Small-angle neutron scattering experiments, supported by molecular dynamics simulations, have been performed on a range of compositions of the [C2mim]1-x[C12mim]x[Tf2N] ionic liquid mixture system. Isotopic contrast variation, through selective deuteration of both cations, has been used to assist in fitting the data to different scattering models. These data, and subsequent fitting, show that the structure of the ionic liquid mixtures changes substantially as a function of composition. Mixtures where x < 0...
September 26, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28931812/evidence-for-percolation-diffusion-of-cations-and-reordering-in-disordered-pyrochlore-from-accelerated-molecular-dynamics
#17
Romain Perriot, Blas P Uberuaga, Richard J Zamora, Danny Perez, Arthur F Voter
Diffusion in complex oxides is critical to ionic transport, radiation damage evolution, sintering, and aging. In complex oxides such as pyrochlores, anionic diffusion is dramatically affected by cation disorder. However, little is known about how disorder influences cation transport. Here, we report results from classical and accelerated molecular dynamics simulations of vacancy-mediated cation diffusion in Gd2Ti2O7 pyrochlore, on the microsecond timescale. We find that diffusion is slow at low levels of disorder, while higher disorder allows for fast diffusion, which is then accompanied by antisite annihilation and reordering, and thus a slowing of cation transport...
September 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/28891160/co2-angiography-colorless-odorless-but-definitely-not-useless
#18
EDITORIAL
Robert D Safian
Contemporary approaches to minimize the risk of acute kidney injury from radiographic contrast (AKI-RC) rely on preferential use of low- or non-ionic contrast; pre-hydration; and limiting contrast volume. This study utilized a meta-analysis of 677 patients to compare the risk of AKI-RC after CO2 peripheral angiography versus iodinated contrast (4.3% vs. 11.1%, odds ratio [OR] 0.465, P = 0.048). There was no difference in AKI-RC in patients with CKD. This study has many limitations. CO2 angiography is an important technique; proper understanding of its strengths and limitations is essential...
September 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28880082/perovskite-type-incoo3-with-low-spin-co-3-effect-of-in-o-covalency-on-structural-stabilization-in-comparison-with-rare-earth-series
#19
Koji Fujita, Takahiro Kawamoto, Ikuya Yamada, Olivier Hernandez, Hirofumi Akamatsu, Yu Kumagai, Fumiyasu Oba, Pascal Manuel, Ryo Fujikawa, Suguru Yoshida, Masayuki Fukuda, Katsuhisa Tanaka
Perovskite rare-earth cobaltites ACoO3 (A = Sc, Y, La-Lu) have been of enduring interest for decades due to their unusual structural and physical properties associated with the spin-state transitions of low-spin Co(3+) ions. Herein, we have synthesized a non-rare-earth perovskite cobaltite, InCoO3, at 15 GPa and 1400 °C and investigated its crystal structure and magnetic ground state. Under the same high-pressure and high-temperature conditions, we also prepared a perovskite-type ScCoO3 with an improved cation stoichiometry in comparison to that in a previous study, where synthesis at 6 GPa and 1297 °C yielded a perovskite cobaltite with cation mixing on the A-site, (Sc0...
September 7, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28857310/orotracheal-manganese-enhanced-mri-memri-an-effective-approach-for-lung-tumor-detection
#20
Andrea Bianchi, Oliviero L Gobbo, Sandrine Dufort, Lucie Sancey, François Lux, Olivier Tillement, Jean-Luc Coll, Yannick Crémillieux
Lung cancer is a primary cause of cancer deaths worldwide. Timely detection of this pathology is necessary to delay or interrupt lung cancer progression, ultimately resulting in a possible better prognosis for the patient. In this context, magnetic resonance imaging (MRI) is especially promising. Ultra-short echo time (UTE) MRI sequences, in combination with gadolinium-based contrast agents, have indeed shown to be especially adapted to the detection of lung neoplastic lesions at submillimeter precision. Manganese-enhanced MRI (MEMRI) increasingly appears to be a possible effective alternative to gadolinium-enhanced MRI...
August 31, 2017: NMR in Biomedicine
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