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https://www.readbyqxmd.com/read/28917614/age-and-fecundability-in-a-north-american-preconception-cohort-study
#1
Amelia K Wesselink, Kenneth J Rothman, Elizabeth E Hatch, Ellen M Mikkelsen, Henrik T Sørensen, Lauren A Wise
BACKGROUND: There is a well-documented decline in fertility treatment success with increasing female age; however, there are few preconception cohort studies examining female age and natural fertility. In addition, data on male age and fertility is inconsistent. Given the increasing number of couples attempting conception at older ages, a more detailed characterization of age-related fecundability in the general population is of great clinical utility. OBJECTIVE: To examine the association between female and male age with fecundability...
September 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28914852/-efficiency-of-immunosuppressive-therapy-in-virus-negative-and-virus-positive-patients-with-morphologically-verified-lymphocytic-myocarditis
#2
O V Blagova, A V Nedostup, E A Kogan, V A Sulimov
AIM: To evaluate the efficiency of immunosuppressive therapy (IST) in virus-negative (V-) and virus-positive (V+) patients with lymphocytic myocarditis (LM). SUBJECTS AND METHODS: 60 patients (45 males) (mean age 46.7±11.8 years) with dilated cardiomyopathy (mean left ventricular (LV) end diastolic size (EDS) 6.7±0.7 cm; ejection fraction (EF) 26.2±9.1%) were examined. The diagnosis of active/borderline LM was verified by right ventricular endomyocardial biopsy in 38 patients, by intraoperative LV biopsy in 10, in the study of explanted hearts from 3 patients and at autopsy in 9...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28912936/combination-of-q-switched-nd-yag-and-fractional-erbium-yag-lasers-in-treatment-of-melasma-a-randomized-controlled-clinical-trial
#3
Shiva Alavi, Ehsan Abolhasani, Sharin Asadi, Mohammadali Nilforoushzadeh
Introduction: Ablative and nonablative lasers have been used to treat melasma. We aimed to assess and compare the combining Q-switched Nd:YAG laser (QSNYL) and fractional erbium:YAG laser (FEYL) with QSNYL alone in treatment of melasma. Methods: This randomized controlled clinical trial was performed in our Research Center during 2013-2014. Women with melasma and without a history of keloid formation, hypersensitivity to hydroquinone, or pigmentary changes due to laser therapy were randomly allocated to receive four sessions of either QSNYL-FEYL combination or QSNYL alone...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/28912704/reliability-of-eeg-measures-of-interaction-a-paradigm-shift-is-needed-to-fight-the-reproducibility-crisis
#4
Yvonne Höller, Andreas Uhl, Arne Bathke, Aljoscha Thomschewski, Kevin Butz, Raffaele Nardone, Jürgen Fell, Eugen Trinka
Measures of interaction (connectivity) of the EEG are at the forefront of current neuroscientific research. Unfortunately, test-retest reliability can be very low, depending on the measure and its estimation, the EEG-frequency of interest, the length of the signal, and the population under investigation. In addition, artifacts can hamper the continuity of the EEG signal, and in some clinical situations it is impractical to exclude artifacts. We aimed to examine factors that moderate test-retest reliability of measures of interaction...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28911510/long-term-prognostic-value-of-gasping-during-out-of-hospital-cardiac%C3%A2-arrest
#5
Guillaume Debaty, Jose Labarere, Ralph J Frascone, Marvin A Wayne, Robert A Swor, Brian D Mahoney, Robert M Domeier, Michael L Olinger, Brian J O'Neil, Demetris Yannopoulos, Tom P Aufderheide, Keith G Lurie
BACKGROUND: Gasping is a natural reflex that enhances oxygenation and circulation during cardiopulmonary resuscitation (CPR). OBJECTIVES: This study sought to assess the relationship between gasping during out-of-hospital cardiac arrest and 1-year survival with favorable neurological outcomes. METHODS: The authors prospectively collected incidence of gasping on all evaluable subjects in a multicenter, randomized, controlled, National Institutes of Health-funded out-of-hospital cardiac arrest clinical trial from August 2007 to July 2009...
September 19, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28910930/-emotional-and-behavioral-problems-associated-with-sleep-problems-in-preschool-aged-children
#6
Y X Chen, X Y Erigene, K Wu, W P Huang, S H Yu, H Y Chen, A H Ye, F B Zhang, Fangbiao Tao
Objective: To examine whether sleep problems are related to both emotional and behavioral problems in children aged 3-6 years. Methods: A large cross-sectional study was conducted in Anqing, Wuhu, Tongling and Yangzhou from March to June 2015. A total of 8 900 preschool aged children were included. Sleep problems were obtained by using adapted BISQ completed by the parents or the people who took care of children. Emotional and behavioral problems of the children were accessed by using Strengths and Difficulties Questionnaire (SDQ), and multivariate logistic regression model was used for statistical analyses...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28910891/-clinical-study-of-aged-patients-with-secondary-benign-paroxysmal-positional-vertigo
#7
Z J Zhu, L P Wei, Z X Xu, H J Xu, Q Liu, N Luo
Objective: To investigate the clinical features and evaluate the efficacy of manual reduction in treatment of age patients with secondary benign paroxysmal positional vertigo (s-BPPV). Methods: Thirty-two cases of aged patients ( the s-BPPV group: including 19 cases of female and 13 males, age from 60 to 86 years old)with secondary benign paroxysmal positional vertigo from Jul. 2013 to Sep. 2015 in our hospital were retrospectively analyzed. The results were compared with 121 patients( the primary group: including 82 cases of female and 39males, aged from 60 to 86 years old)with aged primary benign paroxysmal positional vertigo(p -BPPV)...
September 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28910874/-expression-of-c3d-in-normal-human-liver-tissues-with-non-immunologic-osmostic-mechanism
#8
H J Huang, C Y Feng, Z Y Zheng
Objective: To observe the deposition of complement C3d at different development stages in human normal organs and tissues, and investigate the significance of its deposition. Methods: Using immunohistochemical methods, the deposition of C3d was detected at different development stages of 60 normal human organs and tissue specimens and double staining was performed in some specimens. Ninty-five cases of other organs or tissues were collected as control group. Results: In 50 of 60 livers, it was observed the deposition of C3d in Glisson's capsule and periportal sheath, with irregular linear network-like disposition surrounding the portal sheath...
September 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28910438/long-term-outcomes-of-subtotal-septal-reconstruction-in-rhinoplasty
#9
Scott A Asher, Akta S Kakodkar, Dean M Toriumi
Importance: Significant nasal septal deviation may require complex reconstruction to achieve complete correction. Subtotal septal reconstruction is a method for addressing deviations in the L-strut. Objectives: To review the long-term outcomes of subtotal septal reconstruction and provide objective evidence of functional and aesthetic improvement. Design, Setting, and Participants: This medical record review obtained data on 144 patients who underwent subtotal septal reconstruction from September 1, 2008, to September 1, 2013...
September 14, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28910431/hla-mismatched-microtransplant-in-older-patients-newly-diagnosed-with-acute-myeloid-leukemia-results-from-the-microtransplantation-interest-group
#10
Mei Guo, Nelson J Chao, Jian-Yong Li, David A Rizzieri, Qi-Yun Sun, Ann Mohrbacher, Elizabeth F Krakow, Wan-Jun Sun, Xu-Liang Shen, Xin-Rong Zhan, De-Pei Wu, Li Liu, Juan Wang, Min Zhou, Lin-Hua Yang, Yang-Yi Bao, Zheng Dong, Bo Cai, Kai-Xun Hu, Chang-Lin Yu, Jian-Hui Qiao, Hong-Li Zuo, Ya-Jing Huang, Anthony D Sung, Jun-Xiao Qiao, Zhi-Qing Liu, Tie-Qiang Liu, Bo Yao, Hong-Xia Zhao, Si-Xuan Qian, Wei-Wei Liu, Rafael Forés, Rafael F Duarte, Hui-Sheng Ai
Importance: The outcome of older patients with acute myeloid leukemia (AML) remains unsatisfactory. Recent studies have shown that HLA-mismatched microtransplant could improve outcomes in such patients. Objective: To evaluate outcomes in different age groups among older patients with newly diagnosed AML who receive HLA-mismatched microtransplant. Design, Setting, and Participants: This multicenter clinical study included 185 patients with de novo AML at 12 centers in China, the United States, and Spain in the Microtransplantation Interest Group...
September 14, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28910267/surveillance-for-certain-health-behaviors-and-conditions-among-states-and-selected-local-areas-behavioral-risk-factor-surveillance-system-united-states-2013-and-2014
#11
Sonya Gamble, Tebitha Mawokomatanda, Fang Xu, Pranesh P Chowdhury, Carol Pierannunzi, David Flegel, William Garvin, Machell Town
PROBLEM: Chronic diseases and conditions (e.g., heart diseases, stroke, arthritis, and diabetes) are the leading causes of morbidity and mortality in the United States. These conditions are costly to the U.S. economy, yet they are often preventable or controllable. Behavioral risk factors (e.g., excessive alcohol consumption, tobacco use, poor diet, frequent mental distress, and insufficient sleep) are linked to the leading causes of morbidity and mortality. Adopting positive health behaviors (e...
September 15, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/28906363/predictors-of-noninstitutionalized-survival-1-year-after-hip-fracture-a-prospective-observational-study-to-develop-the-marburg-rehabilitation-tool-for-hip-fractures-marthi
#12
Benjamin Buecking, Daphne Eschbach, Matthias Knobe, Ludwig Oberkircher, Monika Balzer-Geldsetzer, Richard Dodel, Robert Sielski, Bettina Doering, Steffen Ruchholtz, Christopher Bliemel
Hip fractures are frequent fractures in geriatric patients. These fractures have great socioeconomic implications because of the significantly higher risk of mortality and institutionalization. The aim of this study was to develop a prognostic tool to predict survival without institutionalization within 1 year after hip fracture.A total of 402 hip fracture patients aged >60 years (84% community-dwelling) were included in a prospective observational cohort study. Multiple regression analyses determined independent predictors for noninstitutionalized 1-year survival...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28904634/treatment-of-chronic-stable-slipped-capital-femoral-epiphysis-via-surgical-hip-dislocation-with-combined-osteochondroplasty-and-imhauser-osteotomy
#13
J B Erickson, W P Samora, K E Klingele
PURPOSE: Treatment of slipped capital femoral epiphysis (SCFE), including the modified Dunn procedure, restores anatomy with significant risk for avascular necrosis (AVN), if performed in the setting of moderate to severe, stable SCFE. The Imhauser osteotomy has been shown to be an effective way to correct residual deformity without the risk of AVN. We sought to evaluate the effectiveness and safety of a combined Imhauser osteotomy and osteochondroplasty, performed via a surgical hip dislocation approach for the acute and delayed treatment of stable SCFE...
August 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28903892/effectiveness-of-smartmoms-a-novel-ehealth-intervention-for-management-of-gestational-weight-gain-randomized-controlled-pilot-trial
#14
Leanne M Redman, L Anne Gilmore, Jeffrey Breaux, Diana M Thomas, Karen Elkind-Hirsch, Tiffany Stewart, Daniel S Hsia, Jeffrey Burton, John W Apolzan, Loren E Cain, Abby D Altazan, Shelly Ragusa, Heather Brady, Allison Davis, J Mick Tilford, Elizabeth F Sutton, Corby K Martin
BACKGROUND: Two-thirds of pregnant women exceed gestational weight gain (GWG) recommendations. Because excess GWG is associated with adverse outcomes for mother and child, development of scalable and cost-effective approaches to deliver intensive lifestyle programs during pregnancy is urgent. OBJECTIVE: The aim of this study was to decrease the proportion of women who exceed the Institute of Medicine (IOM) 2009 GWG guidelines. METHODS: In a parallel-arm randomized controlled trial, 54 pregnant women (age 18-40 years) who were overweight (n=25) or obese (n=29) were enrolled to test whether an intensive lifestyle intervention (called SmartMoms) decreased the proportion of women with excess GWG, defined as exceeding the 2009 IOM guidelines, compared to no intervention (usual care group)...
September 13, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28903447/locoregionally-recurrent-head-and-neck-squamous-cell-carcinoma-incidence-survival-prognostic-factors-and-treatment-outcomes
#15
Jer-Hwa Chang, Chia-Che Wu, Kevin Sheng-Po Yuan, Alexander T H Wu, Szu-Yuan Wu
PURPOSE: For locoregionally recurrent head and neck squamous cell carcinoma (HNSCC), appropriate therapeutic decisions remain unclear. We examined the treatment outcomes of a national cohort to determine suitable treatments for and prognostic factors in patients with locoregionally recurrent HNSCCs at different stages and sites. PATIENTS AND METHODS: We analyzed data of >20-year-old patients with HNSCC at American Joint Committee on Cancer clinical stages I-IV without metastasis from Taiwan National Health Insurance and cancer registry databases...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28902930/association-between-polymorphisms-in-the-apob-gene-and-hyperlipidemia-in-the-chinese-yugur-population
#16
Q-L Gu, Y Han, Y-M Lan, Y Li, W Kou, Y-S Zhou, X-J Hai, B Yan, C-H Ci
We investigated the influence of apolipoprotein B gene (APOB) variants on the risk of hyperlipidemia (HL) in 631 middle-aged and elderly members of the Chinese Yugur population (HL, n=336; normolipidemia, n=295). APOB polymorphisms were identified using mass spectrometry, and five single nucleotide polymorphisms (rs1042034, rs2163204, rs512535, rs676210, and rs679899) and serum lipids were further analyzed. rs1042034 and rs676210 were significantly associated with HL (P<0.05). Compared with the GG or AA genotype, individuals with AG and AG+AA in rs1042034 and with AG and AG+GG in rs676210 had a 1...
September 12, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28902817/-clinical-efficacy-of-electric-stimulation-of-crural-muscles-in-comprehensive-treatment-of-post-thrombotic-disease
#17
V V Ryzhkin, K V Lobastov, A V Vorontsova, I V Schastlivtsev, V E Barinov, E K Naumov, L A Laberko
The purpose of the study was to evaluate clinical efficacy of electromyostimulation (EMS) of the crural muscles as part of comprehensive therapy for post-thrombotic disease in patients with residual venous obstruction in the femoropopliteal segment. We carried out a prospective comparative clinical study enrolling patients having endured a fist episode of clinically unprovoked venous thrombosis of the femoropopliteal segment and completed the standard 6-month course of anticoagulant therapy and presenting with ultrasonographic signs of complete recanalization of the proximal venous segments (stenosis of 20% and more from the vessel's initial diameter), as well as scoring 5 points and more by the Villalta scale...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28902458/the-impact-of-some-natural-phenolic-compounds-on-carbonic-anhydrase-acetylcholinesterase-butyrylcholinesterase-and-%C3%AE-glycosidase-enzymes-an-antidiabetic-anticholinergic-and-antiepileptic-study
#18
Parham Taslimi, Cuneyt Caglayan, İlhami Gulcin
Natural products from food and plant sources have been used for medicinal usage for ages. Also, natural products with therapeutic significance are compounds derived from animals, plants, or any microorganism. In this study, chrysin, carvacrol, hesperidin, zingerone, and naringin as natural phenols showed excellent inhibitory effects against human (h) carbonic anhydrase (CA) isoforms I and II (hCA I and II), α-glucosidase (α-Gly), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE). These phenolic compounds were tested for the inhibition of α-glycosidase, hCA I, hCA II, AChE, and BChE enzymes and demonstrated efficient inhibition profiles with Ki values in the range of 3...
September 13, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28902119/determination-of-vertical-jump-as-a-measure-of-neuromuscular-readiness-and-fatigue
#19
Casey M Watkins, Saldiam R Barillas, Megan A Wong, David C Archer, Ian J Dobbs, Robert G Lockie, Jared W Coburn, Tai T Tran, Lee E Brown
Coaches closely monitor training loads and periodize sessions throughout the season to create optimal adaptations at the proper time. However, only monitoring training loads ignores the innate physiological stress each athlete feels individually. Vertical jump (VJ) is widely used as a measure of lower body power, and has been used in post-match studies to demonstrate fatigue levels. However, no pre-training monitoring via VJ performance has been previously studied. Therefore, the purpose of this study was to determine the sensitivity of VJ as a measure of readiness and fatigue on a daily sessional basis...
September 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28902011/meibomian-gland-dysfunction-associated-with-periocular-radiotherapy
#20
Young Jun Woo, JaeSang Ko, Yong Woo Ji, Tae-Im Kim, Jin Sook Yoon
PURPOSE: To investigate the influence of periocular radiotherapy on meibomian glands. METHODS: We evaluated 28 patients (40 eyes) who received radiotherapy (RT group) for conjunctival or orbital lymphoma and 30 age-matched control subjects (60 eyes). Subjects underwent slit-lamp examination of the eyelids, Schirmer test, meibography, and evaluation of tear film breakup time (TBUT), Ocular Surface Disease Index (OSDI) scores, meibomian glands evaluation (meiboscore, meibum expressibility, and lid margin abnormality scores), and tear film lipid layer thickness using an ocular surface interferometer...
September 8, 2017: Cornea
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