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pancreatitis acute classification

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https://www.readbyqxmd.com/read/29660323/nationwide-trends-in-acute-and-chronic-pancreatitis-among-privately-insured-children-and-non-elderly-adults-in-the-united-states-2007-2014
#1
Zachary M Sellers, Donna MacIsaac, Helen Yu, Melody Dehghan, Ke-You Zhang, Rachel Bensen, Jessie J Wong, Cindy Kin, K T Park
BACKGROUND & AIMS: Epidemiologic analyses of acute and chronic pancreatitis (AP and CP) provide insight into causes and strategies for prevention, and affect allocation of resources to its study and treatment. We sought to determine current and accurate incidences of AP and CP, along with the prevalence of CP, in children and adults in the United States. METHODS: We collected data from the Truven MarketScan Research Databases of commercial inpatient and outpatient insurance claims in the United States from 2007 through 2014 (patients 0-64 years old)...
April 13, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29657614/acute-pancreatitis-in-children
#2
Urszula Grzybowska-Chlebowczyk, Martyna Jasielska, Anna Flak-Wancerz, Sabina Więcek, Katarzyna Gruszczyńska, Wojciech Chlebowczyk, Halina Woś
Introduction: The acute pancreatitis is a rare disease, but it has started to be diagnosed more often in children. Aim: The aim of the study was single-centre, retrospective analysis of the incidence, aetiology, and clinical course of acute pancreatitis in children. Material and methods: We analysed the medical records of patients with acute pancreatitis hospitalised in the Gastroenterology Unit of the Paediatrics Department, Medical University of Silesia from Jan 2004 to Dec 2013...
2018: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29644912/amalgamation-of-systemic-inflammatory-response-syndrome-score-with-c-reactive-protein-level-in-evaluating-acute-pancreatitis-severity-in-children
#3
Wei Zheng, Linqian Zhang, Gao Long, Bo Chen, Xiaoli Shu, Mizu Jiang
BACKGROUND AND AIM: Systemic inflammatory response syndrome (SIRS) has to do with how the body reacts to injury. Herein, we analyzed the clinical features of acute pancreatitis (AP) in children with SIRS complication and investigated the role of SIRS score combined with C-reactive protein (CRP) level in assessing AP severity in children. METHODS: This retrospective cohort study involved 111 children hospitalized with AP at the Children's Hospital of Zhejiang University School of Medicine between January 2012 and August 2017...
April 12, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29600506/prediabetes-directly-deteriorates-into-diabetic-ketoacidosis-and-hyperosmolar-hyperglycemic-syndrome-triggered-by-acute-pancreatitis-a-case-report-illustrating-a-chicken-and-egg-paradigm-in-ketosis-prone-diabetes
#4
Runbo Song, Shanjin Cao
INTRODUCTION: Diabetic crises occur most often in patients with type 1 diabetes and occasionally in type 2 diabetes, especially under stressful conditions. However, a diabetic crisis occurring directly from prediabetes is an unusual phenomenon. CASE REPORT: A 45-year-old woman presented with postprandial left upper quadrant abdominal pain, nausea, and vomiting. She had a past medical history of prediabetes with impaired fasting glucose and HbA1c 6.4%. On admission, routine laboratory tests showed high anion gap metabolic acidosis (pH 6...
March 29, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29575044/correlation-between-neutrophil-lymphocyte-ratio-and-ranson-score-in-acute-pancreatitis
#5
Bahri Abaylı, Genco Gençdal, Şerife Değirmencioğlu
BACKGROUND: Acute pancreatitis (AP) is characterized by inflammation of the pancreas, elevated pancreatic enzymes, and abdominal pain. The neutrophil to lymphocyte ratio (NLR) is used as a marker of inflammation. In this retrospective study, we aimed to investigate novel early prognostic predictors of AP, such as NLR and its correlation with the Ranson score. METHODS: A total 435 patients (Male: 152; 34.9%, Age: 63.53 ± 17.22 years) were included in the study...
March 24, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29560666/persistent-systemic-inflammatory-response-syndrome-predicts-the-need-for-tertiary-care-in-acute-pancreatitis
#6
Biku Joseph John, Swaminathan Sambandam, Prerna Garg, Gursharan Singh, Maninder Kaur, Rathi Baskaran, Gautham Srinivasan, Venkatakrishnan Leelakrishnan, Krishnaveni Janarthan
INTRODUCTION: Patients with Acute Pancreatitis (AP) presenting with Systemic Inflammatory Response syndrome (SIRS) are more likely to have severe acute pancreatitis and are at increased risk of complications. Additionally, persistence of SIRS at 48 hrs after admission is associated with persistent organ failure and a worse outcome. We investigated the usefulness of SIRS as a criterion for referring patients to a tertiary pancreatic care centre. MATERIAL AND METHODS: Retrospective analyses of patients admitted with AP over a one year period...
July 2017: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29521066/new-predictor-of-acute-necrotizing-pancreatitis-red-cell-distribution-width
#7
Mehmet Suat Yalçın, Adnan Tas, Banu Kara, Sehmus Olmez, Bunyamin Saritas
BACKGROUND: Acute pancreatitis (AP) is inflammation of the pancreas of various severity ranging from mild abdominal pain to mortality. AP may be classified as acute interstitial edematous pancreatitis (AEP) or acute necrotizing pancreatitis (ANP), according to the revised Atlanta criteria. Most of the patients with AP are AEP (75-85% of patients), while 15-25% of patients have ANP. The mortality rate is 3% in AEP and 15% in ANP. Thus, it is important to predict the severity of AP to decrease the morbidity and mortality...
February 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29513171/persistent-systemic-inflammatory-response-syndrome-predicts-the-need-for-tertiary-care-in-acute-pancreatitis
#8
B J John, S Sambandam, P Garg, G Singh, B Edizer, M Kaur, R Baskaran, G Srinivasan, V Leelakrishnan, K Janarthan
INTRODUCTION: Patients with Acute Pancreatitis (AP) presenting with Systemic Inflammatory Response syndrome (SIRS) are more likely to have severe acute pancreatitis and are at increased risk of complications. Additionally, persistence of SIRS at 48 hrs after admission is associated with persistent organ failure and a worse outcome. We investigated the usefulness of SIRS as a criterion for referring patients to a tertiary pancreatic care centre. MATERIALS METHODS: Retrospective analyses of patients admitted with AP over a one year period...
July 2017: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29468366/utility-of-ct-classifications-to-predict-unfavorable-outcomes-in-children-with-acute-pancreatitis
#9
Yojhan E Izquierdo, Eileen V Fonseca, Luz-Ángela Moreno, Rubén D Montoya, Rafael Guerrero Lozano
BACKGROUND: Computed tomography (CT) is useful for the diagnosis of local complications in children with acute pancreatitis but its role as a prognostic tool remains controversial. OBJECTIVE: To establish the correlation between the CT Severity Index and the Revised Atlanta Classification regarding unfavorable outcomes such as severe acute pancreatitis and need for Pediatric Special Care Unit attention in children with acute pancreatitis. MATERIALS AND METHODS: We conducted a retrospective and concordance cohort study in which we obtained abdominal CT scans from 30 patients ages 0 to 18 years with acute pancreatitis...
February 21, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29398347/epc-hpsg-evidence-based-guidelines-for-the-management-of-pediatric-pancreatitis
#10
REVIEW
Andrea Párniczky, Maisam Abu-El-Haija, Sohail Husain, Mark Lowe, Grzegorz Oracz, Miklós Sahin-Tóth, Flóra K Szabó, Aliye Uc, Michael Wilschanski, Heiko Witt, László Czakó, Tassos Grammatikopoulos, Ib Christian Rasmussen, Robert Sutton, Péter Hegyi
BACKGROUND: Pediatric pancreatitis is an underdiagnosed disease with variable etiology. In the past 10-15 years the incidence of pediatric pancreatitis has increased, it is now 3.6-13.3 cases per 100,000 children. Up-to-date evidence based management guidelines are lacking for the pediatric pancreatitis. The European Pancreatic Club, in collaboration with the Hungarian Pancreatic Study Group organized a consensus guideline meeting on the diagnosis and management of pancreatitis in the pediatric population...
January 4, 2018: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29390422/type-v-hypertriglyceridemia-in-children-a-therapeutic-challenge-in-pediatrics-a-case-report-and-a-review-of-the-literature
#11
Cristina Oana Mărginean, Lorena Elena Meliţ, Minodora Dobreanu, Maria Oana Mărginean
RATIONALE: Hypertriglyceridemia is defined as a level of triglycerides above 150 mg/dL. The complex causes and classification of hypertriglyceridemia lead to difficulties in the diagnosis and management of this condition. PATIENT CONCERNS: We present the case of a 15 years and 6 months old female teenager, admitted in our clinic for the following complaints: severe abdominal pain predominantly in the lateral left quadrant, nausea, vomiting, and the lack of stools for 2 days...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29358867/association-between-acute-pancreatitis-and-small-intestinal-bacterial-overgrowth-assessed-by-hydrogen-breath-test
#12
Mei Zhang, Hong-Ming Zhu, Fang He, Bang-Yi Li, Xiao-Cui Li
AIM: To elucidate the effects of small intestinal bacterial overgrowth (SIBO) on the severity and complications of acute pancreatitis (AP). METHODS: In total, 208 patients with AP as defined by the revised Atlanta classification were admitted to Xuanwu Hospital of Capital Medical University from 2013 to 2016. All patients were admitted within 72 h of AP onset. The hydrogen breath test was performed 7 d after AP onset to detect hydrogen production and evaluate the development of SIBO...
December 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29332096/higher-thrombin-antithrombin-iii-complex-levels-may-indicate-severe-acute-pancreatitis
#13
Sami Fidan, Murat Erkut, Arif Mansur Cosar, Yasar Yogun, Asım Örem, Mehmet Sönmez, Mehmet Arslan
AIM: Coagulation disorders may develop in association with severe acute pancreatitis (AP). Plasma thrombin-antithrombin III complex (TAT) levels are one of the principal markers of coagulation disorder. The purpose of this study was to evaluate TAT and other hemostatic parameters in patients with AP and to examine whether or not these parameters indicate the severity of AP. METHOD: Forty-six patients with AP (14 severe, 32 non-severe) and a 30-member healthy control group were recruited...
2018: Digestive Diseases
https://www.readbyqxmd.com/read/29287582/acute-pancreatitis-a-rare-but-serious-complication-for-living-liver-donors-risk-factors-and-outcomes
#14
Adil Baskiran, Metin Kement, Bora Barut, Oguzhan Ozsay, Serdar Karakas, Cemalettin Koç, Sezai Yilmaz
OBJECTIVES: The purposes of this study were to determine the incidence of acute pancreatitis after living donor hepatectomy and to investigate potential risk factors and outcomes. MATERIALS AND METHODS: Clinical data of all donors who underwent donor hepatectomy between January 2015 and December 2016 in our liver transplant institute were reviewed. Donor data were obtained from a prospectively maintained database. The donors were divided into 2 groups according to whether they developed postoperative pancreatitis...
December 29, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29215631/which-patients-with-mild-acute-pancreatitis-require-prolonged-hospitalization
#15
Harkirat Singh, Amir Gougol, Rawad Mounzer, Dhiraj Yadav, Efstratios Koutroumpakis, Adam Slivka, David C Whitcomb, Georgios I Papachristou
OBJECTIVES: In our experience, a subset of mild acute pancreatitis (AP) patients, as defined by the Revised Atlanta Classification, has longer than expected hospitalization. Our aims are to report the prevalence of patients with mild AP who have a prolonged length of stay (LOS), evaluate the etiology, thoroughly phenotype, and finally compare this subset to those with expected LOS. METHODS: Patients admitted with AP from 2003 to 2015 were prospectively enrolled into this cohort study...
December 7, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/29215544/the-251-a-t-polymorphism-in-the-il8-promoter-is-a-risk-factor-for-acute-pancreatitis
#16
Shrinivas Bishu, Efstratios Koutroumpakis, Rawad Mounzer, Kimberly Stello, Nijole Pollock, Anna Evans, David C Whitcomb, Georgios I Papachristou
OBJECTIVES: Inflammation in the setting of acute pancreatitis (AP) is partially driven by pathogen recognition receptors that recognize damage-associated molecular patterns. Interleukin (IL)-8 is a chemotactic factor produced by pathogen recognition receptor-expressing cells. A single-nucleotide polymorphism in IL8 promoter region (-251 A/T) has been implicated in inflammatory diseases. We examined whether this IL8 polymorphism confers susceptibility to AP. METHODS: Patients with AP (n = 357) were prospectively recruited...
January 2018: Pancreas
https://www.readbyqxmd.com/read/29215534/incidence-and-predictors-of-readmissions-in-acute-pancreatitis-a-nationwide-analysis
#17
Sushil Kumar Garg, James P Campbell, Chimaobi Anugwom, Vaibhav Wadhwa, Rajeshwar Singh, Nancy Gupta, Madhusudhan R Sanaka
OBJECTIVES: Acute pancreatitis (AP) is a common cause for hospitalization, and readmission is common, with variable associated risk factors for readmission. Here, we assessed the incidence and risk factors for readmission in AP in a large national database. METHODS: We analyzed data from the National Readmission Database during the year 2013. Index admissions with a primary discharge diagnosis of AP using the International Classification of Diseases, Ninth Revision, Clinical Modification were identified from January to November to identify 30-day readmission rates...
January 2018: Pancreas
https://www.readbyqxmd.com/read/29209119/how-severe-is-moderately-severe-acute-pancreatitis-clinical-validation-of-revised-2012-atlanta-classification
#18
Povilas Ignatavicius, Aiste Gulla, Karolis Cernauskis, Giedrius Barauskas, Zilvinas Dambrauskas
AIM: To explore the outcomes and the appropriate treatment for patients with moderately severe acute pancreatitis (AP). METHODS: Statistical analysis was performed on data from the prospectively collected database of 103 AP patients admitted to the Department of Surgery, Hospital of Lithuanian University of Health Sciences in 2008-2013. All patients were confirmed to have the diagnosis of AP during the first 24 h following admission. The severity of pancreatitis was assessed by MODS and APACHE II scale...
November 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29202530/-a-comparison-between-the-revision-of-atlanta-classification-and-determinant-based-classification-in-acute-pancreatitis
#19
COMPARATIVE STUDY
D Wu, B Lu, H D Xue, Y M Lai, J M Qian, H Yang
Objective: To compare the performance of the revision of Atlanta classification (RAC) and determinant-based classification (DBC) in acute pancreatitis. Methods: Consecutive patients with acute pancreatitis admitted to a single center from January 2001 to January 2015 were retrospectively analyzed. Patients were classified into mild, moderately severe and severe categories based on RAC and were simultaneously classified into mild, moderate, severe and critical grades according to DBC. Disease severity and clinical outcomes were compared between subgroups...
December 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29201763/role-of-clinical-biochemical-and-imaging-parameters-in-predicting-the-severity-of-acute-pancreatitis
#20
Dina Zerem, Omar Zerem, Enver Zerem
Aim: The assessment of the severity of acute pancreatitis (AP) is important for proper management of the disease and for its prognosis. The aim was to correlate clinical, biochemical, and imaging diagnostic parameters and evaluate their prognostic values in the early assessment of severity of AP. Materials and methods: We prospectively studied 128 consecutive patients with AP. The predictors were clinical, biochemical, and imaging diagnostic parameters. The outcome measure was the occurrence of complications...
January 2017: Euroasian Journal of Hepato-Gastroenterology
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