Stephanie Gaengler, Angélique Sadlon, Caroline De Godoi Rezende Costa Molino, Walter C Willett, JoAnn E Manson, Bruno Vellas, Elisabeth Steinhagen-Thiessen, Arnold Von Eckardstein, Frank Ruschitzka, René Rizzoli, José A P da Silva, Reto W Kressig, John Kanis, E John Orav, Andreas Egli, Heike A Bischoff-Ferrari
BACKGROUND: The effects of non-pharmaceutical interventions in the prevention of cardiovascular diseases (CVD) in older adults remains unclear. Therefore, the aim was to investigate the effect of 2000 IU/day of vitamin D3 , omega-3 fatty acids (1 g/day), and a simple home strength exercise program (SHEP) (3×/week) on lipid and CVD biomarkers plasma changes over 3 years, incident hypertension and major cardiovascular events (MACE). METHODS: The risk of MACE (coronary heart event or intervention, heart failure, stroke) was an exploratory endpoint of DO-HEALTH, incident hypertension and change in biomarkers were secondary endpoints...
January 9, 2024: Journal of Nutrition, Health & Aging