keyword
https://read.qxmd.com/read/38251655/ferredoxin-1-is-essential-for-embryonic-development-and-lipid-homeostasis
#21
JOURNAL ARTICLE
Shakur Mohibi, Yanhong Zhang, Vivian Perng, Mingyi Chen, Jin Zhang, Xinbin Chen
Mammalian ferredoxin 1 and 2 (FDX1/2) belong to an evolutionary conserved family of iron-sulfur cluster containing proteins and act as electron shutters between ferredoxin reductase (FDXR) and numerous proteins involved in critical biological pathways. FDX1 is involved in biogenesis of steroids and bile acids, Vitamin A/D metabolism, and lipoylation of tricarboxylic acid (TCA) cycle enzymes. FDX1 has been extensively characterized biochemically but its role in physiology and lipid metabolism has not been explored...
January 22, 2024: ELife
https://read.qxmd.com/read/38247534/association-between-oxidative-stress-with-psychological-and-biochemical-variables-in-a-sample-of-healthy-mexican-people-a-cross-sectional-study
#22
JOURNAL ARTICLE
Ana Míriam Saldaña-Cruz, Sergio Gabriel Gallardo-Moya, Liliana Campos-Medina, Aniel Jessica Leticia Brambila-Tapia
Oxidative stress (OS) has been linked to cell damage and chronic disease development; however, the study of psychological factors related with OS has been limited, as has its relationship with biochemical and personal variables. Therefore, the aim of this study was to evaluate the association between a wide variety of personal, psychological, and biochemical factors with OS in a sample of healthy Mexican people. A total of 134 participants, from which 70 (52%) were women, without known chronic conditions were included in the study, and the molecule 8-hydroxy-2'-deoxyguanosine (8-OHdG) was also measured as a marker of OS...
January 17, 2024: Antioxidants (Basel, Switzerland)
https://read.qxmd.com/read/38226372/nutraceutical-effects-of-justicia-carnea-leaf-powder-supplementations-on-performance-blood-indices-heat-shock-protein-70-oxidative-deoxyribonucleic-acid-damage-biomarkers-and-intestinal-microbes-of-broiler-chickens-under-tropical-condition
#23
JOURNAL ARTICLE
O D Oloruntola, S O Ayodele, O A Jimoh, D A Oloruntola, C O Osowe
The main reason preventing broiler chickens from reaching their genetic potential and hurting their performance in the tropics is heat stress. This study aimed to ascertain how Justicia carnea leaf powder (JLP) supplementation affects broiler chickens' performance, blood indices, antioxidant status, and gut microflora in tropical environments. A completely randomized method was used to assign 240 Cobb 500 broiler chicks to the experimental diets (6 replicates per diet, 10 birds per replication). Diet 1 included no supplement (negative control), diet 2 included 200 mg/kg vitamin C (positive control), diet 3 included 2,500 mg/kg JLP, and diet 4 included 5,000 mg/kg JLP...
August 2023: Archives of Razi Institute
https://read.qxmd.com/read/38224323/vitamin-d-levels-and-lipid-profile-in-children-and-adolescents-a-tight-correlation
#24
JOURNAL ARTICLE
Daniele Ceruti, Carla Colombo, Martina Loiodice, Simone DE Leo, Valeria Calcaterra, Valentina Fabiano
INTRODUCTION: Vitamin D is an essential hormone for humans, playing an important role in musculoskeletal and calcium homeostasis. Its deficiency/insufficiency seems to contribute to the development of cardiometabolic diseases in adults: this correlation appears less clear for children and adolescents. The aim of this paper was to review literature data on the relationship between vitamin D and lipid profile alterations in pediatric population. EVIDENCE ACQUISITION: We carried out a comprehensive research in electronic databases, including MEDLINE and PubMed up to December 2022, for cross-sectional or prospective studies that investigated the correlation between serum vitamin D levels and lipid profile in children and adolescents...
January 15, 2024: Minerva pediatrics
https://read.qxmd.com/read/38220370/is-vitamin-d-deficiency-associated-with-retinopathy-in-type-2-diabetes-mellitus-a-case-control-study
#25
JOURNAL ARTICLE
Maryam Zahedi, Mohammad Mehdi Motahari, Farima Fakhri, Nastaran Moeini Aphshari, Shayan Poursharif, Romina Jahed, Omid Nikpayam
BACKGROUND AND AIMS: This study aimed to determine the associations between vitamin D deficiency and diabetic retinopathy (DR) progression risk in type 2 diabetes mellitus (T2DM) patients. METHODS: This is a case-control study that enrolled 201 diabetic retinopathy (DR) patients as case and 201 T2DM without DR as a control. Demographic variables were obtained during an interview using a questionnaire, furthermore, anthropometric measures were evaluated based on the standard protocol...
February 2024: Clinical Nutrition ESPEN
https://read.qxmd.com/read/38213245/taohong-siwu-decoction-ameliorates-atherosclerosis-in-rats-possibly-through-toll-like-receptor-4-myeloid-differentiation-primary-response-protein-88-nuclear-factor-%C3%AE%C2%BAb-signal-pathway
#26
JOURNAL ARTICLE
Chang Fengjin, Zhou Peng, L I Guoying, Zhang Weizhi, Zhang Yanyan, Peng Daiyin, Chen Guangliang
OBJECTIVE: To investigate the effect of Taohong Siwu decoction (, TSD) on atherosclerosis in rats as well as investigate the underlying mechanism based on molecular docking. METHODS: Sixty healthy male Sprague-Dawley rats were randomly divided into 6 groups with 10 rats in each group: control group, model group, atorvastatin group (AT, 2.0 mg/kg), and TSD groups (20, 10, 5 g/kg) after 7 d of acclimation. The model of atherosclerosis was successfully established except the control group by high fat diet (HFD) and vitamin D2 ...
February 2024: Journal of Traditional Chinese Medicine
https://read.qxmd.com/read/38199870/effects-of-vitamin-d-omega-3-and-a-simple-strength-exercise-programme-in-cardiovascular-disease-prevention-the-do-health-randomized-controlled-trial
#27
JOURNAL ARTICLE
Stephanie Gaengler, Angélique Sadlon, Caroline De Godoi Rezende Costa Molino, Walter C Willett, JoAnn E Manson, Bruno Vellas, Elisabeth Steinhagen-Thiessen, Arnold Von Eckardstein, Frank Ruschitzka, René Rizzoli, José A P da Silva, Reto W Kressig, John Kanis, E John Orav, Andreas Egli, Heike A Bischoff-Ferrari
BACKGROUND: The effects of non-pharmaceutical interventions in the prevention of cardiovascular diseases (CVD) in older adults remains unclear. Therefore, the aim was to investigate the effect of 2000 IU/day of vitamin D3 , omega-3 fatty acids (1 g/day), and a simple home strength exercise program (SHEP) (3×/week) on lipid and CVD biomarkers plasma changes over 3 years, incident hypertension and major cardiovascular events (MACE). METHODS: The risk of MACE (coronary heart event or intervention, heart failure, stroke) was an exploratory endpoint of DO-HEALTH, incident hypertension and change in biomarkers were secondary endpoints...
January 9, 2024: Journal of Nutrition, Health & Aging
https://read.qxmd.com/read/38192498/relationship-of-vitamin-d-deficiency-with-kidney-disease-in-patients-with-type-2-diabetes-mellitus-t2dm-in-the-makkah-region-a-cross-sectional-study
#28
JOURNAL ARTICLE
Ahmad A Obaid, Abdulrahman Mujalli, Wesam F Farrash, Rami Hatem Tayeb, Rashad Jameel Bougeis, Alaa Adel Aljehani, Bandar Ali Alshehri, Sulafa Ezzat Sharaf, Saud Fahad Alqurashi
AIM: Vitamin D deficiency is linked with type 2 diabetes mellitus (T2DM) and the occurrence of complications in patients with type 2 diabetes mellitus. None of the studies have focused on the association between vitamin D levels in patients with type 2 diabetes mellitus and diabetic nephropathy (DN) in the Makkah region, Saudi Arabia. Hence, the purpose of this study is to investigate the relationship of vitamin D with kidney disease in patients with T2DM in the Makkah region, of Saudi Arabia...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38179961/impact-of-phthalate-metabolites-on-vitamin-d-levels-and-subclinical-inflammation-national-health-and-nutrition-examination-survey-2013-2018
#29
JOURNAL ARTICLE
Elhassan Mahmoud, Abdalla Moustafa Elsayed, Muhammad Zain Kaleem, Hamad A Alkorbi, Amgad M Elshoeibi, Tawanda Chivese, Susu M Zughaier
This study explores the association between phthalates and total vitamin D levels and the link between phthalates exposure and subclinical inflammation using monocyte percentage to high-density lipoprotein cholesterol ratio (MHR), utilizing three National Health and Nutrition Examination Survey (NHANES) survey cycles 2013-2018. This study is cross-sectional, utilizing one-time urine samples from randomly selected NHANES participants to assess phthalate metabolites. An inverse association between vitamin D and all Di(2-ethylhexyl) phthalate (DEHP) metabolites was found...
January 5, 2024: International Journal of Environmental Health Research
https://read.qxmd.com/read/38179878/impact-of-elexacaftor-tezacaftor-ivacaftor-on-lipid-and-fat-soluble-vitamin-levels-and-association-with-body-mass-index
#30
JOURNAL ARTICLE
Tanvi Patel, Kimberly McBennett, Senthilkumar Sankararaman, Teresa Schindler, Krithika Sundaram, Nori Mercuri Minich, Sindhoosha Malay, Katherine Kutney
INTRODUCTION: Cystic fibrosis transmembrane conductance regulator (CFTR) modulators improve gastrointestinal absorption of nutrients and may result in changes in body mass index (BMI), serum lipids, and fat-soluble vitamin levels. We hypothesized that serum lipids and vitamin levels would increase with CFTR modulator therapy and that greater increase in lipids and vitamin levels would be related to greater increase in BMI. METHODS: A retrospective study was performed to evaluate the impact of elexacaftor/tezacaftor/ivacaftor (ETI) on nutritional parameters, serum lipids, and fat-soluble vitamin levels...
January 5, 2024: Pediatric Pulmonology
https://read.qxmd.com/read/38179344/novel-insight-into-the-relationship-of-vitamin-d-hydroxylase-and-vitamin-d-with-obesity-in-patients-with-type-2-diabetes-mellitus
#31
JOURNAL ARTICLE
Maha M Bakhuraysah, Amal F Gharib, Asmaa F Hassan, Ghadi K Al Harthi, Raghad F Al Thobaiti, Maha M Al Adwani, Ahmed D Alharbi, Abdullah S Alzahrani, Khwaimsah M Alsubei, Rana F Al-Asiri
BACKGROUND: In patients with type 2 diabetes mellitus (T2DM) and obesity, there is often a vitamin D deficiency, which is crucial for many physiological processes. The enzyme 25-D hydroxylase activates vitamin D, and its status has been linked to glucose and lipid metabolism in these patients. This study investigates the correlation between the levels of 25-D hydroxylase and 25-hydroxyvitamin D, and their impact on glucose and lipid metabolism in Saudi patients with T2DM and obesity. METHODS: This study involved 150 Saudi participants (ages 35-70) of both genders from King Faisal Medical Complex in Taif...
December 2023: Curēus
https://read.qxmd.com/read/38177036/no-benefit-of-vitamin-d-supplementation-on-muscle-function-and-health-related-quality-of-life-in-primary-cardiovascular-prevention-patients-with-statin-associated-muscle-symptoms-a-randomized-controlled-trial
#32
JOURNAL ARTICLE
Paul Peyrel, Pascale Mauriège, Jérôme Frenette, Nathalie Laflamme, Karine Greffard, Sébastien S Dufresne, Claire Huth, Jean Bergeron, Denis R Joanisse
BACKGROUND: Statins are the leading lipid-lowering drugs, reducing blood cholesterol by controlling its synthesis. Side effects are linked to the use of statins, in particular statin-associated muscle symptoms (SAMS). Some data suggest that vitamin D supplementation could reduce SAMS. OBJECTIVE: The purpose of this study was to evaluate the potential benefits of the vitamin D supplement in a randomized controlled trial. METHODS: Men (n = 23) and women (n = 15) (50...
December 15, 2023: Journal of Clinical Lipidology
https://read.qxmd.com/read/38155808/prevalence-of-vitamin-e-inadequacy-dietary-intake-and-sources-of-alpha-tocopherol-and-predictors-of-alpha-and-gamma-tocopherol-status-in-adolescent-girls-in-central-mozambique
#33
JOURNAL ARTICLE
Liisa Korkalo, Georg Alfthan, Lourdes Fidalgo, Riitta I Freese
An adequate alpha-tocopherol status is important for females at reproductive age. We studied the dietary intake and sources of alpha-tocopherol and alpha- and gamma-tocopherol status indicators in 14-19-year-old girls in Central Mozambique. We also explored factors associated with alpha- and gamma-tocopherol status. The participants ( n 508) were from the cross-sectional ZANE Study that was conducted in 2010. We recruited two separate samples, one in January-February and the other in May-June. We collected venous blood samples and conducted 24 h dietary recall interviews...
2023: Journal of Nutritional Science
https://read.qxmd.com/read/38139156/transcriptomic-changes-in-response-to-form-of-selenium-on-the-interferon-tau-signaling-mechanism-in-the-caruncular-tissue-of-beef-heifers-at-maternal-recognition-of-pregnancy
#34
JOURNAL ARTICLE
Sarah N Carr, Benjamin R Crites, Harshraj Shinde, Phillip J Bridges
We have reported that selenium (Se) provided to grazing beef cattle in an inorganic (ISe) form versus a 1:1 mixture (MIX) of inorganic and organic (OSe) forms affects cholesterol biosynthesis in the corpus luteum (CL), the abundance of interferon tau (IFNτ) and progesterone (P4)-induced mRNAs in the caruncular (CAR) tissue of the endometrium, and conceptus length at maternal recognition of pregnancy (MRP). In this study, beef heifers were supplemented with a vitamin-mineral mix containing 35 ppm Se as ISe or MIX to achieve a Se-adequate status...
December 10, 2023: International Journal of Molecular Sciences
https://read.qxmd.com/read/38137858/using-machine-learning-to-identify-the-relationships-between-demographic-biochemical-and-lifestyle-parameters-and-plasma-vitamin-d-concentration-in-healthy-premenopausal-chinese-women
#35
JOURNAL ARTICLE
Chun-Kai Wang, Ching-Yao Chang, Ta-Wei Chu, Yao-Jen Liang
INTRODUCTION: Vitamin D plays a vital role in maintaining homeostasis and enhancing the absorption of calcium, an essential component for strengthening bones and preventing osteoporosis. There are many factors known to relate to plasma vitamin D concentration (PVDC). However, most of these studies were performed with traditional statistical methods. Nowadays, machine learning methods (Mach-L) have become new tools in medical research. In the present study, we used four Mach-L methods to explore the relationships between PVDC and demographic, biochemical, and lifestyle factors in a group of healthy premenopausal Chinese women...
November 27, 2023: Life
https://read.qxmd.com/read/38137228/a-general-review-of-methodologies-used-in-the-determination-of-cholesterol-c-27-h-46-o-levels-in-foods
#36
REVIEW
Ashwell R Ndhlala, Arzu Kavaz Yüksel, Neslihan Çelebi, Hülya Öztürk Doğan
Cholesterol (C27 H46 O) is a lipid-derived substance found in lipoproteins and cell membranes. It is also one of the main sources for the production of bile acids, vitamin D, and steroid hormones. Today, foods are evaluated by consumers not only according to their taste and nutritional content but also according to their effects on consumer health. For example, many consumers choose foods according to their cholesterol level. The cholesterol in the food can directly affect the blood cholesterol level when consumed, which can lead to cardiovascular diseases...
December 10, 2023: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38131799/factors-associated-with-sars-cov-2-infection-evaluated-by-antibody-response-in-a-sample-of-workers-from-the-emilia-romagna-region-northern-italy
#37
JOURNAL ARTICLE
Stefania Paduano, Michele Granata, Sara Turchi, Alberto Modenese, Pasquale Galante, Alessandro Poggi, Isabella Marchesi, Giuseppina Frezza, Giulia Dervishaj, Roberto Vivoli, Sara Verri, Simona Marchetti, Fabriziomaria Gobba, Annalisa Bargellini
Factors associated with SARS-CoV-2 infection risk are still debated. This case-control study aims to investigate the possible relationship between SARS-CoV-2 infection, evaluated through antibody response, and the main sociodemographic, occupational, clinical-anamnestic, and biochemical factors in a population of Modena province (Northern Italy), mainly workers. Both workers who voluntarily joined the screening campaign proposed by companies and self-referred individuals who underwent serological testing were enrolled...
December 1, 2023: Antibodies
https://read.qxmd.com/read/38110391/diet-in-relation-to-metabolic-sleep-and-psychological-health-status-dimets-protocol-for-a-cross-sectional-study
#38
JOURNAL ARTICLE
Donya Poursalehi, Farnaz Shahdadian, Zahra Hajhashemy, Keyhan Lotfi, Zahra Moradmand, Parisa Rouhani, Sobhan Mohammadi, Elahe Mokhtari, Parvane Saneei
INTRODUCTION: Metabolic disturbances are of major health concerns in the world. In addition to their high prevalence, these disorders have substantial roles in developing other physical and mental diseases. Diet could have a considerable influence on managing the progression of these conditions and their consequent health-related effects. The aim of the 'Diet in relation to Metabolic, sleep and psychological health Status' Project is to explore the association of nutrition with metabolic, sleep and mental health, considering potential mediators including brain-derived neurotrophic factor (BDNF) and adropin...
December 18, 2023: BMJ Open
https://read.qxmd.com/read/38100942/nutritional-value-of-meat-lipid-fraction-obtained-from-mallard-duck-anas-platyrhynchos-reared-in-semiextensive-conditions-for-hunting-purposes
#39
JOURNAL ARTICLE
M A G Quaresma, F Abade Dos Santos, L C Roseiro, A P Ribeiro, J D Ferreira, S P Alves, R J B Bessa
The mallard duck or wild duck (Anas platyrhynchos) is the world's most widespread and numerous dabbling duck, being traditionally hunted across many countries in Europe and North America. This study aims to provide a detailed characterization of mallard duck's meat lipid fraction obtained from farmed specimens, reared for hunting purposes, under semiextensive conditions. The mallard's duck meat total lipid content averaged 2.0 and 4.26 g/100 g of fresh meat in breast and leg meat portions, and its meat comprised 23 individual fatty acids (FA) and 3 dimethylacetals (DMA), independently of the sex or meat portion...
November 27, 2023: Poultry Science
https://read.qxmd.com/read/38068810/the-impact-of-clinical-factors-vitamin-b12-and-total-cholesterol-on-severity-of-anorexia-nervosa-a-multicentric-cross-sectional-study
#40
JOURNAL ARTICLE
Letizia Maria Affaticati, Massimiliano Buoli, Nadia Vaccaro, Francesca Manzo, Alberto Scalia, Sara Coloccini, Tommaso Zuliani, Davide La Tegola, Enrico Capuzzi, Monica Nicastro, Fabrizia Colmegna, Massimo Clerici, Antonios Dakanalis, Alice Caldiroli
Severe forms of Anorexia Nervosa (AN) are characterized by medical complications, psychiatric comorbidity, and high mortality. This study investigated potential associations between clinical/biological factors and the severity of AN, measured by the Body Mass Index (BMI). Red and white blood cells, hemoglobin, platelets, iron, vitamins D and B12, folate, and total cholesterol were measured in a mixed sample of 78 inpatients and outpatients. Linear regressions and one-way analyses of variance (ANOVAs) were carried out to evaluate the relationship between BMI and clinical/biochemical variables...
November 29, 2023: Nutrients
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