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Vitamin D AND cholesterol

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https://www.readbyqxmd.com/read/29349100/vitamin-d-deficiency-associated-with-markers-of-cardiovascular-disease-in-children-with-obesity
#1
Marisa Censani, Hoda T Hammad, Paul J Christos, Tiffany Schumaker
Adult studies have reported associations of low 25-hydroxyvitamin D (25OHD) with dyslipidemia and cardiovascular disease; however, there are scarce pediatric data regarding relationships between vitamin D status and specific lipid markers affecting cardiovascular risk. In this cross-sectional study of children evaluated at university-based pediatric endocrinology clinics, 178 patients meeting criteria for overweight or obesity had 25OHD levels assessed over a 2-year period; 60 of 178 had non-HDL (high-density lipoprotein) cholesterol and fasting lipid parameters performed...
2018: Global Pediatric Health
https://www.readbyqxmd.com/read/29331793/moderate-dose-simvastatin-therapy-potentiates-the-effect-of-vitamin-d-on-thyroid-autoimmunity-in-levothyroxine-treated-women-with-hashimoto-s-thyroiditis-and-vitamin-d-insufficiency
#2
Robert Krysiak, Witold Szkróbka, Bogusław Okopień
BACKGROUND: Vitamin D preparations reduce titers of thyroid antibodies in women with autoimmune thyroiditis. The same effect was induced by high-dose, but not moderate-dose-, statin therapy. No previous study has investigated the impact of concomitant treatment with a statin and vitamin D on thyroid autoimmunity. METHODS: The study included three matched groups of women with Hashimoto's thyroiditis and low vitamin D status. Groups B (n = 19) and C (n = 20) were treated with vitamin D (2000 IU daily)...
July 27, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29330987/pattern-of-dyslipidaemia-and-its-association-with-hypovitaminosis-d-in-type-2-diabetes-mellitus
#3
Farhat Bashir, Zia Ullah Khan, Naresh Kumar Seetlani, Zaman Sheikh
BACKGROUND: Macrovascular atherosclerosis is an important long-term complication of type 2 diabetes mellitus. Concurrent dyslipidaemia acts as an additional risk factor for these complications. Hypovitaminosis D has been associated with adverse cardiovascular events. These modifiable risk factors of cardiovascular disease are inter-related. In the presence of an increasing incidence of type 2 diabetes mellitus and its associated metabolic abnormalities and widespread vitamin D deficiency in Pakistan, this association needs to be investigated...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29329572/socio-demographic-and-lifestyle-determinants-of-dietary-patterns-in-french-speaking-switzerland-2009-2012
#4
Pedro Marques-Vidal, Gérard Waeber, Peter Vollenweider, Idris Guessous
BACKGROUND: Food intake is a complex behaviour which can be assessed using dietary patterns. Our aim was to characterize dietary patterns and associated factors in French-speaking Switzerland. METHODS: Cross-sectional study conducted between 2009 and 2012 in the city of Lausanne, Switzerland, including 4372 participants (54% women, 57.3 ± 10.3 years). Food consumption was assessed using a validated food frequency questionnaire. Dietary patterns were assessed by principal components analysis...
January 12, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29326421/vitamin-d3-fortified-milk-did-not-affect-glycemic-control-lipid-profile-and-anthropometric-measures-in-patients-with-type-2-diabetes-a-triple-blind-randomized-clinical-trial
#5
Saedeh Salehi, Fatemeh Sadeghi, Masoumeh Akhlaghi, Mohammad Amin Hanifpour, Mahdi Roshanzamir
BACKGROUND/OBJECTIVES: The effect of vitamin D on glycemic status of diabetes patients is controversial. The objective was to assess the effect of vitamin D3-fortified milk on cardiometabolic markers of patients with type 2 diabetes. SUBJECTS/METHODS: In this randomized triple-blind, placebo-controlled trial, 102 patients (34 males and 68 females) aged 31-74 years with type 2 diabetes were randomized to receive either 250 ml unfortified or 250 ml 1000 IU vitamin D3-fortified milk daily for 9 weeks...
January 11, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29316405/magnesium-zinc-calcium-vitamin-d-co-supplementation-improves-glycemic-control-and-markers-of-cardio-metabolic-risk-in-gestational-diabetes-a-randomized-double-blind-placebo-controlled-trial
#6
Maryam Karamali, Shahla Bahramimoghadam, Fateme Sharifzadeh, Zatollah Asemi
To the best our knowledge, data on the effects of magnesium-zinc-calcium-vitamin D co-supplementation on glycemic control and markers of cardio-metabolic risk in gestational diabetes mellitus (GDM) are scarce. The purpose of this study was to establish the effects of magnesium-zinc-calcium-vitamin D co-supplementation on glycemic control and markers of cardio-metabolic risk of GDM patients. Sixty patients with GDM, aged 18-40 years old were randomised into two groups to intake either magnesium-zinc-calcium-vitamin D co-supplements or placebo (n=30 each group) for 6 weeks in a randomized, double-blind, placebo-controlled trial...
January 9, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29313442/osteoprotegerin-concentration-is-associated-with-the-presence-and-severity-of-peripheral-arterial-disease-in-type-2-diabetes-mellitus
#7
Katarína Demková, Miriam Kozárová, Zuzana Malachovská, Martin Javorský, Ivan Tkáč
BACKGROUND: Osteoprotegerin plays a role in the development of several bone diseases. In addition, osteoprotegerin may contribute to the development of vascular disease. Little is known about the association between serum osteoprotegerin levels and the presence or severity of peripheral arterial disease (PAD). The aim of this study was to examine the association between serum osteoprotegerin levels and both the presence as well as the severity of lower extremity arterial disease in patients with type 2 diabetes (T2DM)...
January 9, 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29298969/-dietetary-recommendation-for-non-alcoholic-fatty-liver-disease
#8
REVIEW
Anna Jeznach-Steinhagen, Joanna Ostrowska, Aneta Czerwonogrodzka-Senczyna, Iwona Boniecka, Wioletta Gronostajska
Non-alcoholic Fatty Liver Disease (NAFLD) is currently the most common chronic liver disease in the developed world. Nowadays, in the adult population of Europe it is estimated at 14% to 21%. Its most important risk factors are obesity and metabolic syndrome. Introducing lifestyle changes such as: dietary intervention and increased physical activity are the first-line treatment and are intended to support not only NAFLD but also associated diseases such as obesity, insulin resistance, diabetes and dyslipidemia...
December 22, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29298649/an-inflammation-related-nutrient-pattern-is-associated-with-both-brain-and-cognitive-measures-in-a-multiethnic-elderly-population
#9
Yian Gu, Jennifer J Manly, Richard P Mayeux, Adam M Brickman
BACKGROUND: Accumulating evidence suggest that dietary factors are associated with Alzheimer's disease, and brain and cognitive health. It is unclear whether inflammation explains this association. OBJECTIVE: To examine whether an inflammation-related nutrient pattern (INP) was associated with neuroimaging and cognitive measures of brain health. METHOD: The current cross-sectional study included 330 non-demented elderly (mean age 79 years at MRI scan) participants in a multi-ethnic, community-based cohort study who had information on nutritional intakes (estimated from food frequency questionnaire), circulating C-reactive protein and interleukin-6 (measured by ELISA), MRI scans, and cognition...
January 1, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29287191/a-compromised-maternal-vitamin-d-status-is-associated-with-congenital-heart-defects-in-offspring
#10
M P H Koster, L van Duijn, Y H M Krul-Poel, J S Laven, W A Helbing, S Simsek, R P M Steegers-Theunissen
BACKGROUND: Interactions between genetic and environmental factors, including modifiable maternal nutrition and lifestyle, play a significant role in the pathogenesis of most congenital heart defects (CHD). The aim of this study was to investigate associations between periconceptional maternal vitamin D status and the prevalence of CHD in offspring. METHODS: A case-control study was performed in 345 mothers of a child with CHD and 432 mothers of a child without CHD from four tertiary hospitals in the Netherlands between 2003 and 2005...
December 26, 2017: Early Human Development
https://www.readbyqxmd.com/read/29282129/dietary-patterns-plasma-vitamins-and-trans-fatty-acids-are-associated-with-peripheral-artery-disease
#11
Mohsen Mazidi, Nathan D Wong, Niki Katsiki, Dimitri P Mikhailidis, Maciej Banach
BACKGROUND: To investigate the association between dietary patterns (DP), plasma vitamins and trans fatty acids (TFAs) with the likelihood of peripheral artery disease (PAD). METHODS: National Health and Nutrition Examination Survey (NHANES) data for the years 1999-2002 were used. PAD was diagnosed by ankle brachial index assessment. Plasma concentrations of vitamins were measured using high performance liquid chromatography. Vitamin D levels were measured by radioimmunoassay...
December 28, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29273925/safety-and-effectiveness-of-single-anastomosis-duodenal-switch-procedure-2-year-result-from-a-single-us-institution
#12
Rena C Moon, Lori Gaskins, Andre F Teixeira, Muhammad A Jawad
BACKGROUND: Single-anastomosis duodenal switch (DS) was introduced by Sanchez-Pernaute et al. as a modification of the biliopancreatic diversion with duodenal switch. We have published preliminary results of the loop DS as the first report of the procedure in the USA. This study aims to evaluate the loop DS procedures again, in terms of weight loss, comorbidity resolution, complication rate, and address the nutritional concerns. METHODS: A retrospective chart review was performed on initial 128 patients who underwent laparoscopic or robot-assisted laparoscopic single-stage loop DS between December 17, 2013 and September 23, 2016...
December 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29259961/relationship-between-serum-25-hydroxy-vitamin-d-concentration-and-risk-of-metabolic-syndrome-in-patients-with-fatty-liver
#13
Hee-Sook Lim, Tae-Hee Kim, Hae-Hyeog Lee, Soon-Kyung Kim, Bora Lee, Yoon-Hyung Park
Background: The vitamin D deficiency rate in Koreans is still high and dietary intake is insufficient. The purpose of this study was to provide basic data for the management of metabolic syndrome (MetS) by analyzing the effect of vitamin D levels on the MetS in patients with fatty liver. Methods: We analyzed the MetS ratio and serum 25-hydroxy-vitamin D (25[OH]D) concentration in 151 adults diagnosed with fatty liver by using obesity index and blood profiles. We collected data on demographic factors, nutrient intake, and lifestyle habits...
November 2017: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29249178/biomarkers-of-cardiometabolic-health-and-nutritional-status-in-individuals-with-positive-celiac-disease-serology
#14
Joseph Jamnik, David Ja Jenkins, Ahmed El-Sohemy
BACKGROUND: Celiac disease (CD) is an autoimmune disorder characterized by damage to the intestinal mucosa and nutrient malabsorption in severe cases. However, it remains unclear whether nutrient deficiencies and other adverse health effects are prevalent in individuals with positive CD serology identified through screening studies. OBJECTIVE: The objective was to determine whether biomarkers of cardiometabolic health and nutritional status differ between those with positive and negative CD serology identified in a screening study of Canadian adults...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/29247784/efficacy-of-vitamin-d-interventional-strategies-in-saudi-children-and-adults
#15
REVIEW
Nasser M Al-Daghri, Sherif H Abd-Alrahman, Amaresh Panigrahy, Yousef Al-Saleh, Naji Aljohani, Omar S Al-Attas, Majed Alokail, Malak N K Khattak
Despite the amount of sunshine in Saudi Arabia, vitamin D (25(OH)D) deficiency is highly prevalent among Saudis. Several strategies are known to improve 25(OH)D status. The aim of this study was to evaluate the efficacy of different interventional strategies in improving 25(OH)D status in Saudi children and adults. This interventional study was undertaken among 593 out of 1152 Saudi subjects [530 students (aged 13-17 years) and 63 teachers (aged 26-46 years)] over a 6-month period from different secondary schools in Riyadh, Saudi Arabia...
December 13, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29243851/alterations-in-gene-expression-in-vitamin-d-deficiency-down-regulation-of-liver-cyp7a1-and-renal-oat3-in-mice
#16
Holly P Quach, Keumhan Noh, Stacie Y Hoi, Adrie Bruinsma, Geny M M Groothuis, Albert P Li, Edwin C Y Chow, K Sandy Pang
The vitamin D-deficient model, established in C57BL/6 mouse after 8-week feeding of vitamin D-deficient diets in absence or presence of added calcium, was found associated with elevated levels of plasma parathyroid hormone (PTH) and plasma and liver cholesterol, and reduction in cholesterol 7α-hydroxylase (Cyp7a1, rate-limiting enzyme for cholesterol metabolism) and renal Oat3 mRNA/protein expression levels. There was, however, no change in plasma calcium and phosphate levels. Appraisal of the liver revealed up-regulation of mRNA expressions of the small heterodimer partner (Shp) and attenuation of Cyp7a1, which contributed to hypercholesterolemia in vitamin D-deficiency...
December 15, 2017: Biopharmaceutics & Drug Disposition
https://www.readbyqxmd.com/read/29242845/no-effect-of-vitamin-d-supplementation-on-cardiovascular-risk-factors-in-subjects-with-metabolic-syndrome-a-pilot-randomised-study
#17
Stefania E Makariou, Moses Elisaf, Anna Challa, Nikolaos Tentolouris, Evangelos N Liberopoulos
Introduction: Patients with metabolic syndrome (MetS) may have lower 25-hydroxyvitamin D (25(OH)VitD) serum levels compared with non-MetS individuals. Vitamin D (VitD) deficiency is associated with various cardiovascular disease (CVD) risk factors. Yet, the effect of VitD supplementation on MetS remains uncertain. Our aim was to examine the effect of VitD supplementation on CVD risk factors in MetS subjects. Material and methods: This pilot study had a PROBE (prospective, randomised, open-label, blinded end-point) design...
2017: Archives of Medical Sciences. Atherosclerotic Diseases
https://www.readbyqxmd.com/read/29242817/vitamin-d-deficiency-and-association-with-body-mass-index-and-lipid-levels-in-hispanic-american-adolescents
#18
Mohan Kumaratne, Gayle Early, Jasmine Cisneros
In this retrospective study, vitamin D deficiency was examined with body mass index (BMI) and lipid levels in a sample of Hispanic American adolescents. The prevalence of vitamin D deficiency among 234 subjects aged 13 to 19 years was 27.8%. Vitamin D deficiency was significantly associated with a BMI of 85 kg/m2 or higher (odds ratio = 2.02, 95% confidence interval = 1.11-3.69, χ2 = 5.37, P = .021), and 55.6% of the sample were overweight or obese (BMI ≥ 85%). In the overweight or obese subjects, vitamin D deficiency was significantly associated with higher mean lipid levels compared with those with adequate vitamin D levels: total cholesterol = 165 ± 28...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/29239815/provider-recommendations-for-patient-reported-muscle-symptoms-on-statin-therapy-insights-from-the-understanding-statin-use-in-america-and-gaps-in-patient-education-survey
#19
Terry A Jacobson, Abdullah Khan, Kevin C Maki, Eliot A Brinton, Jerome D Cohen
BACKGROUND: Statin-associated muscle symptoms are reported by 10% to 29% of patients in clinical practice and are a major determinant of statin nonadherence, discontinuation, and switching. Little is known about what advice patients receive from their providers when dealing with these symptoms. OBJECTIVE: The objective of the study was to assess patient's reports of provider advice when experiencing new or worsened muscle symptoms while taking a statin. METHODS: Data were analyzed from the Understanding Statin Use in America and Gaps in Education survey, a self-administered internet-based survey of 10,138 adults with a reported history of high cholesterol and statin use...
October 12, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29238479/vitamin-d-receptor-gene-polymorphisms-as-a-risk-factor-for-obesity-in-saudi-men
#20
Ayman Saeed Al-Hazmi, Mazin Mohammed Al-Mehmadi, Sarah Mohammad Al-Bogami, Ashjan Ali Shami, Ahmed Ali Al-Askary, Anas Mohammad Alomery, Saad Saeed Al-Shehri, Haytham Dahlawi, Khadija Abdulrazag, Tariq Ali, Abdalaziz Al-Bogami, Emad Sheshah, Abdalaziz Al-Mutairi, Salh Al-Suhimi, Faris Alharb
Background: The prevalence of obesity and vitamin D deficiency in Saudi Arabia has increased recently. Decreased physical activity might play a role in obesity. Previous studies showed an association between low vitamin D level and its receptor polymorphism with obesity development. Objective: To determine association of low vitamin D level and its receptor polymorphism with obesity in Saudi men. Methods: This case control study was carried out from March 2016 through March 2017...
October 2017: Electronic Physician
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