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https://www.readbyqxmd.com/read/28323547/the-extent-that-health-professionals-suspect-and-address-addiction-to-medicines-in-primary-care-findings-from-a-survey-in-northwest-england
#1
Geoff Bates, Madeleine Cochrane, Adam John Mackridge
Addiction to medicines available over the counter or via prescription is of growing international concern. The authors of the current article ran an online survey of health professionals in general medical practice and community pharmacy settings in Northwest England to explore the frequency of suspecting and responding to addiction to medicines. Health professionals reported frequently identifying addiction to medicines among patients including those with long-term pain, mental health problems, sleep disorders, and other substance use disorders, but that these addictions often go unchallenged...
March 1, 2017: Journal of Addictive Diseases
https://www.readbyqxmd.com/read/28317327/a-research-agenda-for-moving-early-medical-pregnancy-termination-over-the-counter
#2
REVIEW
Nathalie Kapp, Daniel Grossman, Emily Jackson, Laura Castleman, Dalia Brahmi
Given the overall safety profile and increasing availability of medical pregnancy termination drugs, we asked: would the mifepristone-misoprostol regimen for medical termination at ≤10 weeks gestation meet U.S. FDA regulatory criteria for over-the-counter (OTC) approval, and if not, what are the present research gaps? We conducted a literature review of consumer behaviors necessary for a successful OTC application for medical termination ≤10 weeks and identified crucial research gaps. If we were to embark on a development program for OTC or more generally, self-use of medical termination, the critical elements missing are the label comprehension, self -selection and actual use studies...
March 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28314704/over-the-counter-access-to-oral-contraceptives-for-adolescents
#3
REVIEW
Krishna K Upadhya, John S Santelli, Tina R Raine-Bennett, Melissa J Kottke, Daniel Grossman
Oral contraceptives (OCs) are used by millions of women in the U.S. The requirement to obtain OCs by prescription from a clinician may serve as a barrier to contraceptive initiation and continuation for women, in particular adolescents. Over-the-counter (OTC) availability would reduce this barrier and could further reduce unintended pregnancy rates. This review explores the scientific issues and regulatory processes involved in switching OCs to OTC status for minor adolescents. We review: (1) the regulatory criteria for switching a drug to OTC status; (2) risk of pregnancy and safety during use of OCs including combined oral contraceptives and progestin-only pills for adolescents; (3) the ability of adolescents to use OCs consistently and correctly; (4) OTC access to OCs and potential effect on sexual risk behaviors; and (5) the potential for reduced opportunities for clinicians to counsel and provide recommended reproductive health care to adolescents...
March 6, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28295595/optometry-australia-scope-of-practice-survey-2015
#4
Patricia M Kiely, Skye Cappuccio, Ellen McIntyre
BACKGROUND: This paper presents results from the inaugural Scope of Practice Survey of Optometry Australia members conducted in October 2015. The survey gathered information related to confidence in detecting and diagnosing key ocular conditions, grading diabetic retinopathy, prescribing scheduled medicines, access to equipment, confidence using equipment, incidence of patients requiring therapeutic management, referral practices and services provided. METHODS: The survey was developed, piloted, modified and administered to members of Optometry Australia (excluding student and retired members), who had a current email address...
March 13, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28294014/prescribing-power
#5
Xboro
Nurses should be able to prescribe items usually dispensed over the counter. It would make it so much easier than having to bother a GP to prescribe eczema cream.
March 15, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28290947/widespread-use-of-prescription-nonsteroidal-anti-inflammatory-drugs-among-u-s-army-active-duty-soldiers
#6
Leila A Walker, Edward J Zambraski, Roger F Williams
INTRODUCTION: Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain and inflammation by inhibiting prostaglandin synthesis. There is a high incidence of musculoskeletal injuries in the military, which would validate the widespread use of NSAIDs. This study determined the amount and specific types of NSAIDs being prescribed to U.S. Army active duty soldiers. METHODS AND MATERIALS: This study was a quantitative study which utilized an existing database of de-identified data; therefore, institutional review board approval was not required...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28280379/amylmetacresol-2-4-dichlorobenzyl-alcohol-hexylresorcinol-or-carrageenan-lozenges-as-active-treatments-for-sore-throat
#7
Martina Morokutti-Kurz, Christine Graf, Eva Prieschl-Grassauer
Up to 80% of sore throats are caused by viruses. Several over the counter products are available which provide symptomatic, not causal relief. For such lozenges, containing the antiseptics and local anesthetics amylmetacresol (AMC) and 2,4-dichlorobenzyl alcohol (DCBA) or hexylresorcinol (HR), recently an additional virucidal effect was published. Therefore, we tested a set of Strepsils(®) lozenges, containing either HR (Max [#2]) or AMC/DCBA (Original [#3], Extra Strong [#4], Warm [#5], Orange and Vitamin C [#6], Sugar free Lemon [#7], Children/Strawberry [#8] and Soothing Honey and Lemon [#9]) for their antiviral efficiency against representatives of respiratory viruses known to cause sore throat: human rhinovirus (HRV) 1a, HRV8, influenza virus A H1N1n, Coxsackievirus A10, and human coronavirus (hCoV) OC43...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28279072/aspirin-in-older-adults
#8
Mandi Sehgal, Sarah K Wood, Joseph G Ouslander, Charles H Hennekens
In the treatment or secondary prevention of cardiovascular disease (CVD), there is general consensus that the absolute benefits of aspirin far outweigh the absolute risks. Despite evidence from randomized trials and their meta-analyses, older adults, defined as aged 65 years or older, are less likely to be prescribed aspirin than their middle-aged counterparts. In primary prevention, the optimal utilization of aspirin is widely debated. There is insufficient randomized evidence among apparently healthy participants at moderate to high risk of a first CVD event, so general guidelines seem premature...
January 1, 2017: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28265784/-all-i-need-is-help-to-do-well-herbs-medicines-faith-and-syncretism-in-the-negotiation-of-elder-health-treatment-in-rural-ghana
#9
Eileen Smith-Cavros, Joyce Avotri-Wuaku, Albert Wuaku, Amal Bhullar
This qualitative research sought answers to questions about how elders in Agate, Ghana, coped with the challenges of illness in a rural village and in particular how they negotiated treatment for their illnesses within a flawed and limited healthcare system. In our study, 22 of 28 interviewees used all methods available to them (biomedical approaches [doctors and/or hospitals and/or doctor-prescribed medications], herbs, over-the-counter medicines [i.e., acetaminophen painkillers], and faith-based methods [praying/fasting/laying of hands/holy food and/or water]) in attempts to heal their illnesses...
March 6, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28258279/management-of-respiratory-tract-infections-in-young-children-a-qualitative-study-of-primary-care-providers-perspectives
#10
Ruby Biezen, Bianca Brijnath, Danilla Grando, Danielle Mazza
Respiratory tract infections in young children are the most common cause of general practice visits in Australia. Despite the availability of clinical practice guidelines, the treatment and management of respiratory tract infections in young children is inconsistent. The aim of the study was to explore the management of respiratory tract infections in young children from a multi-disciplinary perspective using across-sectional qualitative research design based on the theoretical domains framework and the Capability, Opportunity and Motivation-B model...
December 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28257536/over-the-counter-hearing-aids-the-path-forward
#11
Elizabeth Warren, Chuck Grassley
No abstract text is available yet for this article.
March 3, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28252160/the-effects-of-service-delivery-model-and-purchase-price-on-hearing-aid-outcomes-in-older-adults-a-randomized-double-blind-placebo-controlled-clinical-trial
#12
Larry E Humes, Sara E Rogers, Tera M Quigley, Anna K Main, Dana L Kinney, Christine Herring
Objectives: The objectives of this study were to determine efficacy of hearing aids in older adults using audiology best practices, to evaluate the efficacy of an alternative over-the-counter (OTC) intervention, and to examine the influence of purchase price on outcomes for both service-delivery models. Design: The design of this study was a single-site, prospective, double-blind placebo-controlled randomized trial with three parallel branches: (a) audiology best practices (AB), (b) consumer decides OTC model (CD), and (c) placebo devices (P)...
March 2, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/28247445/detection-of-dna-from-undeclared-animal-species-in-commercial-elimination-diets-for-dogs-using-pcr
#13
Christa Horvath-Ungerboeck, Karoline Widmann, Stefanie Handl
BACKGROUND: Elimination diets are the gold standard for the diagnosis of adverse food reactions (AFR). A broad variety of commercial diets are available containing either hydrolysed protein or novel ingredients which claim to be suitable for elimination diets. Contamination may be one factor accounting for the failure of commercial elimination diet trials. HYPOTHESIS/OBJECTIVES: To test commercial diets labelled as suitable for elimination diets for dogs, for DNA of animal origin other than that declared on the label...
February 28, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28245081/limited-effectiveness-of-over-the-counter-plant-preparations-used-for-the-treatment-of-urinary-tract-infections-as-inhibitors-of-the-urease-activity-from-staphylococcus-saprophyticus
#14
Charles E Deutch
AIMS: Urease is a key virulence factor for the Gram-positive urinary tract pathogen Staphylococcus saprophyticus and a potential target for antimicrobial therapy. The enzyme from S. saprophyticus is unusual in that it does not contain cysteine at the active site. The aims of this study were to test fourteen over-the-counter plant preparations as inhibitors of this urease and to determine if they can prevent the increase in pH that normally occurs in bacterial cultures containing urea...
February 28, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28242966/over-the-counter-mtp-pills-and-its-impact-on-women-s-health
#15
Sarojini, T R Ashakiran, B T Bhanu, Radhika
OBJECTIVES: To study the complications and consequences including maternal morbidity and mortality following indiscriminate self-consumption of abortion pills reporting to a tertiary care center. METHODOLOGY: This is an observational study conducted at Vanivilas hospital between January 2012 to December 2013 for 24 months. After applying inclusion and exclusion criteria, 104 women were studied with respect to period of gestation, parity, clinical features at presentation and management in the institution...
February 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28241932/automated-discovery-of-safety-and-efficacy-concerns-for-joint-muscle-pain-relief-treatments-from-online-reviews
#16
David Z Adams, Richard Gruss, Alan S Abrahams
OBJECTIVES: Product issues can cost companies millions in lawsuits and have devastating effects on a firm's sales, image and goodwill, especially in the era of social media. The ability for a system to detect the presence of safety and efficacy (S&E) concerns early on could not only protect consumers from injuries due to safety hazards, but could also mitigate financial damage to the manufacturer. Prior studies in the field of automated defect discovery have found industry-specific techniques appropriate to the automotive, consumer electronics, home appliance, and toy industries, but have not investigated pain relief medicines and medical devices...
April 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28237389/over-the-counter-otc-artificial-tear-drops-for-dry-eye-syndrome-a-cochrane-review-summary
#17
Loendi van der Westhuizen, Andrew D Pucker
No abstract text is available yet for this article.
November 17, 2016: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28223344/an-intestinal-farnesoid-x-receptor-ceramide-signaling-axis-modulates-hepatic-gluconeogenesis-in-mice
#18
Cen Xie, Changtao Jiang, Jingmin Shi, Xiaoxia Gao, Dongxue Sun, Lulu Sun, Ting Wang, Shogo Takahashi, Mallappa Anitha, Kristopher W Krausz, Andrew D Patterson, Frank J Gonzalez
Increasing evidence supports the view that intestinal farnesoid X receptor (FXR) is involved in glucose tolerance and that FXR signaling can be profoundly impacted by the gut microbiota. Selective manipulation of the gut microbiota-FXR signaling axis was reported to significantly impact glucose intolerance, but the precise molecular mechanism remains largely unknown. Here, caffeic acid phenethyl ester (CAPE), an over-the-counter dietary supplement and an inhibitor of bacterial bile salt hydrolase, increased levels of intestinal tauro-β-muricholic acid, which selectively suppresses intestinal FXR signaling...
March 2017: Diabetes
https://www.readbyqxmd.com/read/28218925/off-label-prescribing-and-polypharmacy-minimizing-the-risks
#19
Laura G Leahy
Off-label prescribing and polypharmacy are commonplace in today's health care environment. Patients are treated with multiple medications obtained through multiple providers, and all too frequently, there is no collaboration amongst professionals. Nurses can address these issues by educating themselves and their patients regarding medication indications and uses, side effects, risks, and benefits. By exploring a patient's medication reconciliation, including over-the-counter agents, and identifying the U.S...
February 1, 2017: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/28216953/therapeutic-potential-of-alpha-ketoglutarate-against-acetaminophen-induced-hepatotoxicity-in-rats
#20
Lalita Mehra, Yasha Hasija, Gaurav Mittal
OBJECTIVE: Alpha-ketoglutarate (α-KG) is a cellular intermediary metabolite of Krebs cycle, involved in energy metabolism, amino acid synthesis, and nitrogen transport. It is available over-the-counter and marketed as a nutritional supplement. There is a growing body of evidence to suggest that dietary α-KG has the potential to maintain cellular redox status and thus can protect various oxidative stress induced disease states. The aim of the present study was to investigate the hepatoprotective role of α-KG in acetaminophen (APAP) induced toxicity in rats...
October 2016: Journal of Pharmacy & Bioallied Sciences
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