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https://www.readbyqxmd.com/read/28544204/receipt-and-use-of-spoken-and-written-over-the-counter-medicine-information-insights-into-australian-and-uk-consumers-experiences
#1
Vivien Tong, David K Raynor, Parisa Aslani
OBJECTIVES: To explore Australian and UK consumers' receipt and use of spoken and written medicine information and examine the role of leaflets for consumers of over-the-counter (OTC) medicines. METHODS: Semistructured interviews were conducted with 37 Australian and 39 UK consumers to explore information received with their most recent OTC medicine purchase, and how information was used at different times post-purchase. Interviews were audio-recorded, transcribed verbatim and thematically analysed...
May 24, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28541171/modeling-the-social-dynamics-of-moral-enhancement-social-strategies-sold-over-the-counter-and-the-stability-of-society
#2
Anders Sandberg, Joao Fabiano
How individuals tend to evaluate the combination of their own and other's payoffs-social value orientations-is likely to be a potential target of future moral enhancers. However, the stability of cooperation in human societies has been buttressed by evolved mildly prosocial orientations. If they could be changed, would this destabilize the cooperative structure of society? We simulate a model of moral enhancement in which agents play games with each other and can enhance their orientations based on maximizing personal satisfaction...
July 2017: Cambridge Quarterly of Healthcare Ethics: CQ: the International Journal of Healthcare Ethics Committees
https://www.readbyqxmd.com/read/28539982/misuse-of-topical-corticosteroids-on-facial-skin-a-study-of-200-patients
#3
Rohini Sharma, Sameer Abrol, Mashqoor Wani
BACKGROUND: Topical corticosteroids have become available as over the counter drugs and are widely misused for various conditions. OBJECTIVE: The aim of this study is to assess the clinical and epidemiological aspects of the unjustified use of topical corticosteroids for facial skin. METHODS: A total of 200 patients with facial dermatoses and topical corticosteroid misapplication daily over face for not less than 30 days were included in the study...
March 31, 2017: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/28538459/patient-comprehension-and-compliance-survey-to-assess-postoperative-pain-regimens-in-the-orthopaedic-trauma-population
#4
Anup K Gangavalli, Ajith Malige, Saqib Rehman, Chinenye O Nwachuku
OBJECTIVE: This study aims to determine the groups of patients who are at risk for noncompliance and misunderstanding of their pain regimen. DESIGN: Survey-based cohort study. SETTING: Suburban Level-I trauma center. PATIENTS/PARTICIPANTS: A total of 171 patients between the ages of 18-89 years who underwent surgical fixation of fractures involving the pelvis, long bones, or periarticular regions of the knee, ankle, elbow, and wrist...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538314/do-neuromuscular-dentistry-designed-mouthguards-enhance-dynamic-movement-ability-in-competitive-athletes
#5
Joshua A Cotter, Steve T Jamison, Sarah A Schloemer, Ajit M W Chaudhari
Cotter, JA, Jamison, ST, Schloemer, SA, and Chaudhari, AMW. Do neuromuscular dentistry-designed mouthguards enhance dynamic movement ability in competitive athletes? J Strength Cond Res 31(6): 1627-1635, 2017-The purpose of this study was to examine the effect of a neuromuscular dentistry-designed mouthguard (NMDD) on dynamic movement ability. Forty-two competitive athletes (8 women, 21.9 ± 2.9 years, 66.8 ± 18.8 kg, 1.68 ± 0.11 m; 34 men, 22.8 ± 4.8 years, 77.4 ± 12.7 kg, 1.78 ± 0.08 m) with greater than 2 years' experience in their designated sport were enrolled in the study...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28534685/biotin-interference-with-routine-clinical-immunoassays-understand-the-causes-and-mitigate-the-risks
#6
Shanika Samarasinghe, Farah Meah, Vinita Singh, Arshi Basit, Nicholas Emanuele, Mary Ann Emanuele, Alaleh Mazhari, Earle W Holmes
OBJECTIVES: The objectives of this report are to review the mechanisms of biotin interference with streptavidin/biotin-based immunoassays, identify automated immunoassay systems vulnerable to biotin interference, describe how to estimate and minimize the risk of biotin interference in vulnerable assays, and review the literature pertaining to biotin interference in endocrine function tests. METHODS: The data in the manufacturer's "Instructions for Use" for each of the methods utilized by seven immunoassay system were evaluated...
May 23, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28533689/medication-related-costs-of-rhinitis-in-australia-a-nostradata-cross-sectional-study-of-pharmacy-purchases
#7
Pete Smith, David Price, Richard Harvey, Andrew Simon Carney, Vicky Kritikos, Sinthia Z Bosnic-Anticevich, Louise Christian, Derek Skinner, Victoria Carter, Alice Marie Sybille Durieux
PURPOSE: There is a relative paucity of research regarding medication expenditure associated with multiple-therapy use for rhinitis in Australia. To describe 1) the nature and extent of multiple-therapy use for rhinitis in Australia using data on therapies purchased with prescription or over-the-counter (OTC) and 2) additional costs incurred by multiple-therapy use compared with intranasal corticosteroid (INCS) therapy alone. PATIENTS AND METHODS: A retrospective observational study was carried out using a database containing anonymous pharmacy transaction data available from 20% of pharmacies in Australia that links doctor prescriptions and OTC purchase information...
2017: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/28532204/management-of-allergic-rhinitis-in-the-era-of-effective-over-the-counter-treatments
#8
Warner W Carr, Barbara P Yawn
Allergic rhinitis (AR) may be regarded as a trivial issue unworthy of the doctor's time, and with the availability of many different over-the-counter (OTC) treatments, up to two thirds of patients self-manage AR before seeking medical care. Yet, AR can have a significant impact on health-related quality of life and is associated with a greater detriment to work productivity than other chronic diseases such as diabetes and hypertension. For many patients, the impact on quality of life is greater than suggested by reported symptoms and should also be a focus of treatment...
May 22, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28524293/the-contribution-of-direct-patient-reported-adrs-to-drug-safety-signals-in-the-netherlands-from-2010-to-2015
#9
Florence van Hunsel, Susan de Waal, Linda Härmark
PURPOSE: The purpose of this study was to investigate the contribution of patient reports to signals sent by the Netherlands Pharmacovigilance Centre Lareb to the Dutch Medicines Evaluation Board and to determine if there are certain types of signals where patient report add a distinct contribution. METHOD: All signals from 2010 until 2015 were included. First, we investigated how many patient reports were present in the signals and the characteristics of these reports compared to the health care professional and marketing authorization holders' reports...
May 19, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28523055/antibiotics-and-over-the-counter-medication-use-and-its-correlates-among-arab-pregnant-women-visiting-a-tertiary-care-hospital-in-riyadh-saudi-arabia
#10
Hafsa Raheel, Sulaiman Alsakran, Abdulkhaliq Alghamdi, Majed Ajarem, Salman Alsulami, Afzal Mahmood
BACKGROUND AND OBJECTIVE: The use of over the counter medications (OTCMs) is a common practice globally. OTCMs are of special concern among pregnant women as they pose risk to the mother and fetus. The objective was to assess the use of OTCMs by pregnant woman, and factors associated with it. METHODS: A cross-sectional study, using a structured self-administrated questionnaire was conducted at the obstetric and antenatal clinics at King Khalid University hospital, Riyadh...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28521601/significance-of-pregnancy-test-false-negative-results-due-to-elevated-levels-of-%C3%AE-core-fragment-hcg
#11
Sarah Johnson, Saji Eapen, Peter Smith, Graham Warren, Michael Zinaman
Very high levels of β-core fragment human chorionic gonadotrophin (βcf-hCG) are reported to potentially cause false negative results in point-of-care (POC)/over-the-counter (OTC) pregnancy tests. To investigate this further, women's daily early morning urine samples, collected prior to conception and during pregnancy, were analysed for intact, free β- and βcf-hCG. The proportion of βcf-hCG was found to be related to that of hCG produced and in circulation. Therefore, best practice for accuracy testing of POC/OTC pregnancy tests would be to test devices against clinical samples containing high levels of βcf-hCG as well as standards spiked with biologically relevant ratios...
May 19, 2017: Journal of Immunoassay & Immunochemistry
https://www.readbyqxmd.com/read/28516288/efficacy-and-safety-of-ibuprofen-in-infants-aged-between-3-and-6-months
#12
Victoria C Ziesenitz, Andreas Zutter, Thomas O Erb, Johannes N van den Anker
Ibuprofen is a non-steroidal anti-inflammatory drug frequently administered to children of various ages for relief of fever and pain and is approved as an over-the-counter medication in many countries worldwide. Although there are extensive data on its efficacy and safety in children and adults, there are divergent dosing recommendations for analgesia and treatment of fever in infants, especially in the age group between 3 and 6 months of age. In this article, we have assessed the safety and efficacy of ibuprofen use in infants in an attempt to find the optimal method of pain and fever management in this specific age group...
May 17, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28513425/actual-use-of-and-adherence-to-ibuprofen-400%C3%A2-mg-tablet-dosing-instructions-in-a-simulated-otc-environment%C3%A2
#13
Suzanne Meeves, Rina Leyva, Clark Richardson, Brenda Wilson, David Savastano
OBJECTIVE: Evaluate adherence of US consumers to proposed label directions for a new 400 mg ibuprofen formulation. METHODS: In this single-arm, open-label, multicenter, 30-day study simulating an over-the-counter (OTC)-like environment, US analgesic consumers reviewed proposed product packaging for a new 400 mg ibuprofen formulation and made a purchase decision. Purchasers used the product as needed and recorded use over 30 days. Outcomes included the percentage of participants who exhibited correct or acceptable product use for the primary endpoint (not exceeding 1,200 mg/day > 2 times during the study) or secondary endpoint (not exceeding 400 mg/dose > 2 times during the study) and adherence to the labeled dosing interval of 6 - 8 hours...
May 17, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28512775/a-porphyrin-based-fluorescence-method-for-zinc-determination-in-commercial-propolis-extracts-without-sample-pretreatment
#14
Gastón Darío Pierini, Victor Hugo A Pinto, Clarissa G C Maia, Wallace D Fragoso, Julio S Reboucas, María Eugenia Centurión, Marcelo Fabián Pistonesi, María Susana Di Nezio
The quantification of zinc in over-the-counter drugs as commercial propolis extracts by molecular fluorescence technique using meso-tetrakis(4-carboxyphenyl)porphyrin (H2 TCPP(4) ) was developed for the first time. The calibration curve is linear from 6.60 to 100 nmol L(-1) of Zn(2+) . The detection and quantification limits were 6.22 nmol L(-1) and 19.0 nmol L(-1) , respectively. The reproducibility and repeatability calculated as the percentage variation of slopes of seven calibration curves were 6.75% and 4...
May 16, 2017: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/28512368/-analysis-of-the-phenomenon-of-over-the-counter-drug-abuse-and-not-controlled-herbs-trade-by-polish-adolescents-part-i
#15
REVIEW
Daria Suchecka, Jolanta Kucharska-Mazur, Katarzyna Groszewska, Monika Mak, Jerzy Samochowiec, Agnieszka Samochowiec
The phenomenon of stupefying by the use of available over-the-counter drugs (OTC) among adolescents is an essential problem in both Poland and throughout the world. Popular analgesics, cold medicine and antihistamines contain psychedelic substances, such as dextromethorphan (DXM), pseudoephedrine/ephedrine, codeine (methylmorphine), dimenhydrinate, paracetamol (acetaminophren) and others. Cases of fatal addiction to dextromethorphan, one of the active substances contained in medicines, e.g., the common cold, have been reported...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28510525/-850-per-bowel-movement-hard-to-justify-that-cost
#16
Thomas Morrow
Constipation can be a serious and painful problem, and we shouldn't dismiss other people's suffering. On the other hand there's a danger when new medications are compared against placebo rather than against over-the-counter products with a history of effectiveness.
March 2017: Managed Care
https://www.readbyqxmd.com/read/28503778/a-topical-zinc-ionophore-blocks-tumorigenic-progression-in-uv-exposed-skh-1-high-risk-mouse-skin
#17
Rebecca Justiniano, Jessica Perer, Anh Hua, Mohammad Fazel, Andrea Krajisnik, Christopher M Cabello, Georg T Wondrak
Nonmelanoma skin cancer (NMSC) is the most common malignancy in the United States representing a considerable public health burden. Pharmacological suppression of skin photo-carcinogenesis has shown promise in preclinical and clinical studies, but more efficacious photochemopreventive agents are needed. Here, we tested feasibility of harnessing pharmacological disruption of intracellular zinc-homeostasis for photochemoprevention in vitro and in vivo. Employing the zinc-ionophore and FDA-approved microbicidal agent zinc pyrithione (ZnPT), used worldwide in over-the-counter (OTC) topical consumer products, we first demonstrated feasibility of achieving ZnPT-based intracellular Zn(2+) -overload in cultured malignant keratinocytes (HaCaT-ras II-4; SCC-25) employing membrane-permeable fluorescent probes...
May 15, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28503226/consumer-views-on-safety-of-over-the-counter-drugs-preferred-retailers-and-information-sources-in-sweden-after-re-regulation-of-the-pharmacy-market
#18
Tommy Westerlund, Sahra Barzi, Cecilia Bernsten
BACKGROUND: The availability of over-the-counter drugs (OTCs) has increased in Sweden since a re-regulation of the pharmacy market in 2009, through which non-pharmacy retailers became permitted to provide certain OTCs. OBJECTIVE: To examine the adult general public's views on safety, purchasing and information channels, storage and disposal of OTCs in Sweden, three years after the re-regulation of the pharmacy market. METHODS: A questionnaire study in 2012-13 in a stratified, random sample of all inhabitants in Sweden ≥ 18 years old...
January 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28503221/management-of-musculoskeletal-pain-in-retail-drug-outlets-within-a-nigerian-community-a-descriptive-study
#19
Samirah N Abdu-Aguye, Aishatu Shehu, Ubaidullah I Ahmad
OBJECTIVE: This work aimed to describe attitudes and practices of both community pharmacies and patent and proprietary medicine vendor (PPMV) outlets towards over-the-counter (OTC) analgesic use for musculoskeletal pain states within Zaria, Nigeria. METHODS: The study was carried out in 2 phases from May to August 2016. Phase one was a cross-sectional survey of 40 retail drug outlets (10 community pharmacies and 30 PPMVs). A simulated patient scenario of a young adult male complaining of acute onset back pain was used to collect data on the type and quality of analgesic recommended, duration of consultation, as well as nature of information provided during the drug dispensing process...
January 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28503217/assessment-and-use-of-drug-information-references-in-utah-pharmacies
#20
Krystal L Moorman, Elyse A Macdonald, Anthony Trovato, Casey R Tak
OBJECTIVE: To determine which drug references Utah pharmacists use most frequently. To determine which types of drug information questions are most commonly asked, and whether Utah pharmacists have access to adequate references to respond to these questions. METHODS: A 19-question survey was created using Qualtrics, LLC (Provo, Utah) software. An electronic survey link was sent to 1,431 pharmacists with a valid e-mail address listed in the Department of Professional Licensing database...
January 2017: Pharmacy Practice
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