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https://www.readbyqxmd.com/read/28639423/emergency-contraceptive-pill-users-risk-perceptions-for-sexually-transmitted-infections-and-future-unintended-pregnancy
#1
Mary T Hickey, Michele G Shedlin
BACKGROUND AND PURPOSE: The availability of emergency contraception pills (ECP) over the counter (OTC) has the potential to reduce the incidence of unintended pregnancy; however, the increased risk for sexually transmitted infection (STI) acquisition, related to unprotected intercourse, has not been adequately addressed. The purpose of this study is to gain insight into risk perceptions for STIs and subsequent unintended pregnancy in women who have purchased ECP OTC. METHODS: Twenty-one women, aged 18-24, attending a private university in an urban setting, who purchased and used ECP OTC participated in 1-h, individual interviews...
June 22, 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/28639298/prevalence-patterns-and-factors-associated-with-psychotropic-use-in-older-adults-with-intellectual-disabilities-in-ireland
#2
M O'Dwyer, J Peklar, N Mulryan, P McCallion, M McCarron, M C Henman
BACKGROUND: People with intellectual disability (ID) are at increased risk of exposure to psychotropic drugs and psychotropic polypharmacy because of the higher prevalence of mental health conditions present and more controversially, the use of these agents to treat challenging behaviours. Despite the fact that many adults with ID are exposed to psychotropic polypharmacy, few studies to date have focused on the patterns of use of multiple psychotropics, or factors associated with psychotropic polypharmacy, particularly in the older population...
June 21, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28632121/anti-inflammatory-treatment-and-risk-for-depression-after-first-time-stroke-in-a-cohort-of-147-487-danish-patients
#3
Ida Kim Wium-Andersen, Marie Kim Wium-Andersen, Martin Balslev Jørgensen, Merete Osler
BACKGROUND: Depression is a common complication after stroke, and inflammation may be a pathophysiological mechanism. This study examines whether anti-inflammatory treatment with acetylsalicylic acid (ASA), nonsteroid anti-inflammatory drugs (NSAID) or statins influence the risk of depression after stroke. METHODS: A register-based cohort including all patients admitted to hospital with a first-time stroke from Jan. 1, 2001, through Dec. 31, 2011, and a nonstroke population with a similar age and sex distribution was followed for depression until Dec...
June 20, 2017: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/28630687/emerging-antimicrobial-resistance-in-early-and-late-onset-neonatal-sepsis
#4
Lamiaa Mohsen, Nermin Ramy, Dalia Saied, Dina Akmal, Niveen Salama, Mona M Abdel Haleim, Hany Aly
BACKGROUND: Compared to developed countries, the use of antimicrobials in Egypt is less regulated and is available over the counter without the need for prescriptions. The impact of such policy on antimicrobial resistance has not been studied. This study aimed to determine the prevalence of early and late onset sepsis, and the frequency of antimicrobial resistance in a major referral neonatal intensive care unit (NICU). METHODS: The study included all neonates admitted to the NICU over a 12-month period...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28629602/management-of-dentin-hypersensitivity-by-practitioners-in-the-national-dental-practice-based-research-network
#5
Dorota T Kopycka-Kedzierawski, Cyril Meyerowitz, Mark S Litaker, Marc W Heft, Nirmala Tasgaonkar, Marianne R Day, Andretta Porter-Williams, Valeria V Gordan, Robin L Yardic, Timothy M Lawhorn, Gregg H Gilbert
BACKGROUND: Dentin hypersensitivity (DH) is a condition commonly encountered in clinical dental practice. The authors conduct a study to identify the treatments recommended to manage DH among dentists in the United States. METHODS: The authors conducted a multicenter study of 1,862 patients with DH who received a diagnosis and were treated by 171 dentists with the National Dental Practice-Based Research Network. RESULTS: The most common treatment recommended was desensitizing over-the-counter (OTC) potassium nitrate toothpaste (alone or in combination with other treatments) for 924 of 1,862 patients (50%)...
June 16, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28628392/potential-drug-drug-and-herb-drug-interactions-in-patients-with-cancer-a-prospective-study-of-medication-surveillance
#6
Allan Ramos-Esquivel, Álvaro Víquez-Jaikel, Cristina Fernández
PURPOSE: Patients with cancer frequently use herbal supplements and concomitant medications along with antineoplastic agents. These patients are at high risk of herb-drug interactions (HDIs) and drug-drug interactions (DDIs). We aimed to determine clinically relevant DDIs and HDIs leading to pharmaceutical intervention. METHODS: Patients starting a new anticancer therapy were asked to complete a questionnaire to identify concomitant use of any over-the-counter drug or herbal supplement...
June 19, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28626504/comparing-healthcare-utilization-and-costs-among-medicaid-insured-patients-with-chronic-noncancer-pain-with-and-without-opioid-induced-constipation-a-retrospective-analysis
#7
Tope Olufade, Amanda M Kong, Nicole Princic, Paul Juneau, Rucha Kulkarni, Kui Zhang, Catherine Datto
BACKGROUND: Constipation is a common adverse effect of opioid use and has been associated with increased healthcare utilization and costs among patients receiving opioids for pain management. OBJECTIVE: To compare the healthcare utilization and costs of Medicaid patients with chronic noncancer pain with and without constipation who were receiving opioids. METHODS: This retrospective, claims-based study was conducted using data from the Truven Health MarketScan Medicaid Multi-State database...
April 2017: American Health & Drug Benefits
https://www.readbyqxmd.com/read/28625446/a-novel-treatment-for-chronic-opioid-use-after-surgery
#8
Paul F White, Ofelia Loani Elvir-Lazo, Hector Hernandez
In a recent article from the Center for Disease Control, the authors addressed the current opioid epidemic in America and emphasized the importance of utilizing non-opioid analgesic alternatives to opioid medication for treating chronic pain. In cases where non-opioid analgesic drugs alone have failed to produce adequate pain relief, these authors suggested that non-pharmacologic therapies should also be considered. This Case Series describes a pilot study designed to evaluate a novel non-pharmacologic approach to treating long-standing (>1year) opioid dependency...
August 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28616436/initiatives-to-reduce-nonprescription-sales-and-dispensing-of-antibiotics-findings-and-implications
#9
Vanda Marković-Peković, Nataša Grubiša, Johanita Burger, Ljubica Bojanić, Brian Godman
OBJECTIVE: Irrational use of antimicrobials is a major driver of antimicrobial resistance, exacerbated by dispensing antibiotics without a prescription. Our previous study suggested this was a problem in the Republic of Srpska despite legislation. Since then, a number of activities have been initiated. Consequently, the study aimed to ascertain whether these multiple initiatives had reduced this. METHODS: Patients visiting all community pharmacies in the Republic from October 2014 to July 2015 presenting with symptoms typical of an acute, viral, and mostly uncomplicated upper respiratory tract infection, with results compared to the previous study...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28615153/-click-for-closer-care-a-content-analysis-of-community-pharmacy-websites-in-four-countries
#10
Sandra Zwier
BACKGROUND: Combinations of professional and commercial communication are typically very controversial, particularly in health care communication on the Internet. Websites of licensed community pharmacies on the other hand tend to raise remarkably little controversy, although they typically contain controversial combinations of clinical and commercial services previously unprecedented in professional health care communication. OBJECTIVE: The aim of this study was to fill the void of knowledge about the combination of clinical and commercial services presented on the websites of licensed community pharmacies...
June 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28610434/isoflavones-and-gastrointestinal-infection-two-potential-triggers-for-reversible-cerebral-vasoconstriction-syndrome
#11
Björn Machner, Tobias Boppel, Thomas Münte
Background Reversible cerebral vasoconstriction syndrome (RCVS) is an important differential diagnosis of singular or recurrent thunderclap headache. Prognosis is generally good, however complications of the transient segmental vasospasms of cerebral arteries such as stroke, subarachnoidal hemorrhage and brain edema may worsen the clinical outcome. Although the exact pathomechanism is still unclear, various vasoactive substances and conditions (e.g. post partum) have been identified as triggering RCVS. Cases We report on the clinical course and management of two cases of typical RCVS that were associated with two different precipitants previously not described: A gastrointestinal infection and isoflavones, which are phytoestrogens used for menopausal vasomotor symptoms...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28609513/in-home-over-the-counter-sleep-apnea-sensor-on-the-horizon
#12
Jennifer Abbasi
No abstract text is available yet for this article.
June 13, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28603893/allodynia-is-associated-with-initial-and-sustained-response-to-acute-migraine-treatment-results-from-the-american-migraine-prevalence-and-prevention-study
#13
Richard B Lipton, Sagar Munjal, Dawn C Buse, Alix Bennett, Kristina M Fanning, Rami Burstein, Michael L Reed
OBJECTIVE: In a population sample of persons with migraine treating with a single category of acute migraine medication, to identify rates and factors associated with acute treatment outcomes, including 2-hour pain freedom (2hPF), 24-hour pain response (24hPR), and 24-hour sustained pain response (24hSPR). Key predictors include acute treatment type (triptans and other medication categories), the influence of allodynia on response to medication, and the interaction between medication category and presence of allodynia in response to treatment among people with migraine...
June 11, 2017: Headache
https://www.readbyqxmd.com/read/28603499/campania-preventability-assessment-committee-italy-a-focus-on-the-preventability-of-non-steroidal-anti-inflammatory-drugs-adverse-drug-reactions
#14
Maurizio Sessa, Liberata Sportiello, Annamaria Mascolo, Cristina Scavone, Silvia Gallipoli, Gabriella di Mauro, Daniela Cimmaruta, Concetta Rafaniello, Annalisa Capuano
Purpose: This study aims to investigate preventability criteria of adverse drug reactions (ADRs) involving non-steroidal anti-inflammatory drugs (NSAIDs) by analyzing individual case safety reports (ICSRs) sent through Campania region (Italy) spontaneous reporting system from July 2012 to October 2016. Methods: For all the ICSRs that reported NSAIDs as suspected drug, a trained multidisciplinary team of Campania Pharmacovigilance Regional Centre composed of clinical pharmacologists and pharmacists with pluriannual experience in Pharmacovigilance assessed preventability by using the P-method...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28597531/attitudes-in-australia-on-the-upscheduling-of-over-the-counter-codeine-to-a-prescription-only-medication
#15
Jacqui McCoy, Raimondo Bruno, Suzanne Nielsen
INTRODUCTION AND AIMS: In December 2016, the Australian Therapeutic Goods Administration announced that over-the-counter (OTC) codeine would be available by prescription-only in February 2018. Prior to this announcement, the authors aimed to evaluate attitudes among Australian codeine consumers, pharmacists and general medical practitioners (GP) towards the proposed upscheduling of OTC codeine. DESIGN AND METHODS: Public Therapeutic Goods Administration submissions on codeine upscheduling were assessed, and a brief questionnaire was developed to assess the common issues raised...
June 8, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28594339/cardiac-dysrhythmias-associated-with-substitutive-use-of-loperamide-a-systematic-review
#16
Irbaz Bin Riaz, Muhammad Shahzeb Khan, Muhammad Umar Kamal, Qurat-Ul-Ain Riaz Sipra, Anum Riaz, Umar Zahid, Sandipan Bhattacharjee
BACKGROUND: Recently, several deaths secondary to cardiac arrhythmias have been reported in association with substitutive use of loperamide. Therefore, we conducted a systematic review of all reported cases to overview the epidemiologic patterns and clinical outcomes to better elucidate loperamide-induced cardiac complications. AREAS OF UNCERTAINTY: Association between substitutive use of loperamide and cardiac arrhythmias. DATA SOURCES: A comprehensive literature search was conducted across 6 databases using variety of keywords to identify all reports of cardiac side effects associated with loperamide abuse...
April 27, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28593214/association-between-gender-and-drug-cost-for-over-the-counter-minoxidil
#17
Mackenzie R Wehner, Kevin T Nead, Jules B Lipoff
No abstract text is available yet for this article.
June 7, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28589268/e-cigarette-users-attitudes-on-the-banning-of-sales-of-nicotine-e-liquid-its-implication-on-e-cigarette-use-behaviours-and-alternative-sources-of-nicotine-e-liquid
#18
Li Ping Wong, Haridah Alias, Nasrin Agha Mohammadi, Azadeh Ghadimi, Victor Chee Wai Hoe
The banning of sales of nicotine e-liquid in e-cigarette shops has been implemented in several states in Malaysia. The distribution of nicotine e-liquid can only be allowed by licensed pharmacies or registered medical practitioners. This study aimed to evaluate e-cigarette users' responses to the control policy in a cross-sectional survey of 851 e-cigarette users by utilizing a self-report questionnaire that assessed (1) attitudes on regulation policy of e-cigarette banning; (2) e-cigarette use behaviors; and (3) sources of e-liquid after the regulation policy has been implemented...
June 6, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28588946/assessing-the-independent-and-combined-effects-of-subsidies-for-antimalarials-and-rapid-diagnostic-testing-on-fever-management-decisions-in-the-retail-sector-results-from-a-factorial-randomised-trial-in-western-kenya
#19
Wendy Prudhomme O'Meara, Manoj Mohanan, Jeremiah Laktabai, Adriane Lesser, Alyssa Platt, Elisa Maffioli, Elizabeth L Turner, Diana Menya
OBJECTIVES: There is an urgent need to understand how to improve targeting of artemisinin combination therapy (ACT) to patients with confirmed malaria infection, including subsidised ACTs sold over-the-counter. We hypothesised that offering an antimalarial subsidy conditional on a positive malaria rapid diagnostic test (RDT) would increase uptake of testing and improve rational use of ACTs. METHODS: We designed a 2×2 factorial randomised experiment evaluating 2 levels of subsidy for RDTs and ACTs...
August 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28587476/do-the-new-fda-guidance-documents-help-improving-performance-of-blood-glucose-monitoring-systems-compared-with-iso-15197
#20
Guido Freckmann, Annette Baumstark, Stefan Pleus
Recently, the Food and Drug Administration (FDA) published guidance documents for point-of-care testing (POCT) and over-the-counter (OTC) blood glucose monitoring systems (BGMS). These are expected to improve weaknesses of the already established ISO 15197:2013 standard accuracy evaluation for OTC BGMS; however, the proposed criteria and procedures rather raise new questions. As an example, the OTC guidance stipulates tighter accuracy criteria in the low glycemic range than the POCT guidance for no obvious reason...
June 1, 2017: Journal of Diabetes Science and Technology
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