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Vitamin B1

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https://www.readbyqxmd.com/read/28924437/fundus-findings-in-wernicke-encephalopathy
#1
Tal Serlin, Elad Moisseiev
Wernicke encephalopathy (WE) is an acute neuropsychiatric syndrome resulting from thiamine (vitamin B1) deficiency, classically characterized by the triad of ophthalmoplegia, confusion, and ataxia. While commonly associated with chronic alcoholism, WE may also occur in the setting of poor nutrition or absorption. We present a 37-year-old woman who underwent laparoscopic sleeve gastrectomy and presented with visual disturbance with bilateral horizontal nystagmus, confusion, and postural imbalance. Fundus examination revealed bilateral optic disc edema with a retinal hemorrhage in the left eye...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28914188/a-retrospect-study-on-thiazole-derivatives-as-the-potential-antidiabetic-agents-in-drug-discovery-amp-developments
#2
Gopal L Khatik, Ashok Kumar Datusalia, Waquar Ahsan, Paranjeet Kaur, Manish Vyas, Amit Mittal, Surendra Kumar Nayak
BACKGROUND: Heterocycles containing thiazole, a moiety with sulfur and nitrogen is a core structure which found in a number of biologically active compounds. The thiazole ring is notable as a component of the certain natural products, such as vitamin B1 (thiamine) and penicillins. Thiazole is also known as wonder nucleus and has versatile in different biological fields. A number of new compounds contain heterocycle thiazole moieties, thus it is one of the important areas of research. METHODS: We searched the scientific database using relevant keywords...
September 15, 2017: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/28904494/vitamin-d-deficiency-does-not-influence-reproductive-outcomes-of-ivf-icsi-a-study-of-oocyte-donors-and-recipients
#3
Manish Banker, Dipesh Sorathiya, Sandeep Shah
BACKGROUND: Vitamin D and its active metabolite, 1,25-dihydroxy vitamin D (1,25-(OH)2D3), play a significant role in reproduction. AIM: To assess the effect of serum 25-hydroxy vitamin D level on oocyte quality and endometrial receptivity by studying oocyte donors and their recipients. MATERIALS AND METHODS: This prospective study consisted of two groups: Group A (recipient group) and Group B (donor group). All the participants of Groups A1 and B1 as well as Groups A2 and B2 were subcategorized into vitamin D-deficient (<20 ng/mL) and vitamin D replete-insufficient (20 to ≥30 ng/mL), respectively...
April 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/28904467/post-bariatric-surgery-acute-axonal-polyneuropathy-doing-your-best-is-not-always-enough
#4
Zakia Mohammad Yasawy, Ali Hassan
Neurological complications are frequently recognized with weight reduction surgeries for morbid obesity. The spectrum of peripheral neuropathies complicating the weight loss surgery is wide, and among them, the acute axonal peripheral neuropathy resembling Guillain-Barre syndrome is rare and only less than a dozen cases are reported. We present three cases, which after bariatric surgery developed acute polyneuropathy that rapidly progressed over 4 weeks from the onset. All patients responded to aggressive parenteral Vitamin B1 and B12 replacement therapy...
July 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28890765/evaluation-of-nutritional-composition-of-the-dried-seaweed-ulva-lactuca-from-pameungpeuk-waters-indonesia
#5
Abdullah Rasyid
The nutritional composition of the dried seaweed Ulva lactuca from Pameungpeuk waters, including proximate, vitamins, minerals, dietary fibre and heavy metal has been carried out. The objective of this present study is to know the nutritional composition of the dried seaweed U. lactuca for utilisation in human nutrition in the future. Results show that carbohydrate was the major component in the proximate analysis of U. lactuca in the present study. The carbohydrate content was 58.1%. Moisture, ash, protein and fat content were 16...
July 2017: Tropical Life Sciences Research
https://www.readbyqxmd.com/read/28884726/-polyneuropathies-in-intestinal-diseases
#6
I V Damulin, D A Degterev
Different aspects of polyneuropathies (PN) developed due to the deficit of group B vitamins in intestinal diseases are considered. Neurological disturbances related to intestinal diseases are caused by malabsorption that leads to the deficit of some compounds extremely important for normal cell metabolism, pathological changes of mucous coat of the stomach and intestine and higher sensitivity to the plant protein gluten. Vitamin B12 deficit can lead to a number of neurological disturbances; patients with pernicious anemia most often develop myelopathy and PN...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28880568/macro-and-micronutrients-of-human-milk-composition-are-they-related-to-maternal-diet-a-comprehensive-systematic-review
#7
Mojtaba Keikha, Maryam Bahreynian, Mohammad Saleki, Roya Kelishadi
BACKGROUND: This study aims at systematically reviewing the observational and interventional studies on the association of maternal macro- and micronutrient intake with breast milk content. METHODS: We systematically searched the Medline via PubMed, Scopus, and ISI Web of Knowledge till October 2016 with the following search strategy: ("human milk" OR "breast milk" OR "breast milk composition" OR "human breast milk composition" OR "composition breast milk" OR "mother milk" OR "human breast milk") AND ("maternal diet" OR "maternal nutrition")...
September 7, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28875857/is-there-a-link-between-vitamin-b-and-multiple-sclerosis
#8
Natalie Nemazannikova, Kathleen Mikkelsen, Lily Stojanovska, Gregory L Blatch, Vasso Apostolopoulos
BACKGROUND: Damage to the myelin sheath (demyelination) is one of the main manifestations of multiple sclerosis (MS). Interestingly, both MS and vitamin B deficiency results in severe myelin degeneration that leads to loss in neuronal signal transmission. OBJECTIVE: Deficiency in vitamin B complex vary, although common symptoms include fatigue, increased oxidative stress, inflammation and demyelination. In particular, vitamin B12 (cobalamin) has had increased attention for its role in the methylation process, involvement in myelination and re-myelination, and reversal of MS symptoms...
September 6, 2017: Medicinal Chemistry
https://www.readbyqxmd.com/read/28873391/high-prevalence-of-thiamine-vitamin-b1-deficiency-in-early-childhood-among-a-nationally-representative-sample-of-cambodian-women-of-childbearing-age-and-their-children
#9
Kyly C Whitfield, Geoffry Smith, Chhoun Chamnan, Crystal D Karakochuk, Prak Sophonneary, Khov Kuong, Marjoleine Amma Dijkhuizen, Rathavuth Hong, Jacques Berger, Tim J Green, Frank Tammo Wieringa
BACKGROUND: Thiamine deficiency is thought to be an issue in Cambodia and throughout Southeast Asia due to frequent clinical reports of infantile beriberi. However the extent of this public health issue is currently unknown due to a lack of population-representative data. Therefore we assessed the thiamine status (measured as erythrocyte thiamine diphosphate concentrations; eThDP) among a representative sample of Cambodian women of childbearing age (15-49 y) and their young children (6-69 mo)...
September 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28871327/micronutrient-intake-adequacy-and-depression-risk-in-the-sun-cohort-study
#10
Almudena Sánchez-Villegas, Aurora Pérez-Cornago, Itziar Zazpe, Susana Santiago, Francisca Lahortiga, Miguel Angel Martínez-González
PURPOSE: The aim of the study was to prospectively assess the association between micronutrient intake adequacy and risk of depression. METHODS: This dynamic cohort study involves Spanish university graduates (SUN Project). Dietary intake was assessed at baseline and after 10 years of follow-up with a semi-quantitative food frequency questionnaire. Micronutrient intake adequacy for vitamins B1, B2, B3, B6, B12, C, A, D, E, folic acid, zinc, iodine, selenium, iron, calcium, potassium, phosphorus, magnesium and chrome was estimated...
September 4, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28861696/treatment-of-vitamin-and-mineral-deficiencies-after-biliopancreatic-diversion-with-or-without-duodenal-switch-a-major-challenge
#11
Jens Homan, Wendy Schijns, Edo O Aarts, Ignace M C Janssen, Frits J Berends, Hans de Boer
BACKGROUND: Vitamin and mineral deficiencies are a major concern after biliopancreatic diversion (BPD) and BPD with duodenal switch (BPD/DS). Evidence-based guidelines how to prevent or how to treat deficiencies in these patients are currently lacking. The aim of the current study is to give an overview of postsurgical deficiencies and how to prevent and treat these deficiencies. METHODS: Retrospective evaluation of a 1-year structured monitoring and treatment schedule for various deficiencies in 34 patients after BPD or BPD/DS...
August 31, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28859374/vitamin-b1-diversity-and-characterization-of-biosynthesis-genes-in-cassava
#12
Nathalie Mangel, Jared B Fudge, Teresa B Fitzpatrick, Wilhelm Gruissem, Hervé Vanderschuren
Vitamin B1, which consists of the vitamers thiamin and its phosphorylated derivatives, is an essential micronutrient for all living organisms because it is required as a metabolic cofactor in several enzymatic reactions. Genetic diversity of vitamin B1 biosynthesis and accumulation has not been investigated in major crop species other than rice and potato. We analyzed cassava germplasm for accumulation of B1 vitamers. Vitamin B1 content in leaves and roots of 41 cassava accessions showed significant variation between accessions...
June 15, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28847140/effects-of-b-vitamins-overload-on-plasma-insulin-level-and-hydrogen-peroxide-generation-in-rats
#13
Wuping Sun, Mingzhu Zhai, Qian Zhou, Chengrui Qian, Changyu Jiang
It has been reported that nicotinamide-overload induces oxidative stress associated with insulin resistance, the key feature of type 2 diabetes mellitus (T2DM). This study aimed to investigate the effects of B vitamins in T2DM. Glucose tolerance tests were carried out in adult Sprague-Dawley rats treated with or without cumulative doses of B vitamins. More specifically, insulin tolerance tests were also carried out in adult Sprague-Dawley rats treated with or without cumulative doses of Vitamin B3. We found that cumulative Vitamin B1 and Vitamin B3 administration significantly increased the plasma H₂O₂ levels associated with high insulin levels...
August 31, 2017: Chinese Journal of Physiology
https://www.readbyqxmd.com/read/28846867/simultaneous-measurement-of-whole-blood-vitamin-b1-and-vitamin-b6-using-lc-esi-ms-ms
#14
R J A C Roelofsen-de Beer, B D van Zelst, R Wardle, P G Kooij, Y B de Rijke
Vitamin B1 and B6 have recently been included in the Dutch clinical guidelines for the general practitioner in the differential diagnosis of dementia. To keep up with the sharp rise in the number of requests, an LC-MS/MS method using stable isotopes as internal standards was developed. The active vitamers thiamine pyrophosphate (TPP) and pyridoxal-5'-phosphate (PLP) in whole blood are simultaneously measured with a short run time of 2min. Whole blood is mixed with internal standard solution containing both TPP-d3 and PLP-d3, followed by deproteinization with a trichloroacetic acid (TCA) solution...
August 12, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28830473/survival-outcomes-of-hepatectomy-for-stage-b-hepatocellular-carcinoma-in-the-bclc-classification
#15
Toshiya Kamiyama, Tatsuya Orimo, Kenji Wakayama, Shingo Shimada, Akihisa Nagatsu, Hideki Yokoo, Hirofumi Kamachi, Kenichiro Yamashita, Tsuyoshi Shimamura, Akinobu Taketomi
BACKGROUND: Because hepatectomy is not recommended in patients with stage B hepatocellular carcinoma (HCC) of the Barcelona Clinic Liver Cancer (BCLC) staging, we evaluated the survival outcomes of hepatectomy for stage B in the BCLC system. METHODS: Data were collected from 297 consecutive adult stage B patients who underwent curative hepatectomy for HCC between 1996 and 2014 in Hokkaido University Hospital. Overall survival (OS), disease-free survival (DFS), and risk factors were analyzed using the Kaplan-Meier method...
August 22, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28808005/conformational-dynamics-of-1-deoxy-d-xylulose-5-phosphate-synthase-on-ligand-binding-revealed-by-h-d-exchange-ms
#16
Jieyu Zhou, Luying Yang, Alicia DeColli, Caren Freel Meyers, Natalia S Nemeria, Frank Jordan
The enzyme 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) is a key enzyme in the methylerythritol 4-phosphate pathway and is a target for the development of antibiotics, herbicides, and antimalarial drugs. DXPS catalyzes the formation of 1-deoxy-d-xylulose 5-phosphate (DXP), a branch point metabolite in isoprenoid biosynthesis, and is also used in the biosynthesis of thiamin (vitamin B1) and pyridoxal (vitamin B6). Previously, we found that DXPS is unique among the superfamily of thiamin diphosphate (ThDP)-dependent enzymes in stabilizing the predecarboxylation intermediate, C2-alpha-lactyl-thiamin diphosphate (LThDP), which has subsequent decarboxylation that is triggered by d-glyceraldehyde 3-phosphate (GAP)...
August 29, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28806727/formation-of-friable-embryogenic-callus-in-cassava-is-enhanced-under-conditions-of-reduced-nitrate-potassium-and-phosphate
#17
Yoshinori Utsumi, Chikako Utsumi, Maho Tanaka, Vu The Ha, Akihiro Matsui, Satoshi Takahashi, Motoaki Seki
Agrobacterium-mediated transformation is an important research tool for the genetic improvement of cassava. The induction of friable embryogenic callus (FEC) is considered as a key step in cassava transformation. In the present study, the media composition was optimized for enhancing the FEC induction, and the effect of the optimized medium on gene expression was evaluated. In relative comparison to MS medium, results demonstrated that using a medium with reducing nutrition (a 10-fold less concentration of nitrogen, potassium, and phosphate), the increased amount of vitamin B1 (10 mg/L) and the use of picrolam led to reprogram non-FEC to FEC...
2017: PloS One
https://www.readbyqxmd.com/read/28806113/-hungarian-diet-and-nutritional-status-survey-the-otap2014-study-v-vitamin-intake-of-the-hungarian-population
#18
Erzsébet Schreiberné Molnár, Zsuzsanna Nagy-Lőrincz, Barbara Nagy, Márta Bakacs, Orsolya Kis, Eszter Sarkadi Nagy, Éva Martos
INTRODUCTION AND AIM: The Hungarian Diet and Nutritional Status Survey was implemented on a sub-sample of the European Health Interview Survey. In this paper, the authors present the data on the vitamin intake of the Hungarian population. METHOD: The survey represents the vitamin intake of the Hungarian non-institutionalised adult population of 18 years and older. There are significant differences between men's and women's vitamin intake. RESULTS: The intake of all water-soluble vitamins except for vitamin C is higher in men than in women, and the difference between the genders regarding the intake of vitamin E and D is significant...
August 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28799782/effects-of-nutrient-and-bioactive-food-components-on-alzheimer-s-disease-and-epigenetic
#19
Elİf Celİk, Nevİn Sanlİer
Alzheimer's disease (AD) is the most common form of dementia in the elderly and is a chronic neurodegenerative disease that is becoming widespread. For this reason, in recent years factors affecting the development, progression and cognitive function of the AD have been emphasized. Nutrients and other bioactive nutrients are among the factors that are effective in AD. In particular, vitamins A, C and E, vitamins B1, B6 and B12, folate, magnesium, choline, inositol, anthocyanins, isoflavones etc. nutrients and bioactive nutrients are known to be effective in the development of AD...
August 11, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28763984/solvation-behavior-and-sweetness-response-of-carbohydrates-their-derivatives-and-sugar-alcohols-in-thiamine-hcl-vitamin-b1-and-pyridoxine-hcl-vitamin-b6-at-different-temperatures
#20
Parampaul K Banipal, Mousmee Sharma, Tarlok S Banipal
Volumetric properties are important tools to study the solvation behavior of solutes and reveal valuable information about solute-solute/cosolute interactions. Therefore, standard partial molar volumes at infinite dilution have been calculated from density measurements for monosaccharides, their methoxy and deoxy derivatives, disaccharides and sugar alcohols in (0.05, 0.15, 0.25 and 0.35)molkg(-1) thiamine HCl(aq) and pyridoxine HCl(aq) solutions over temperature range (288.15-318.15)K at pressure, p=0.1MPa...
December 15, 2017: Food Chemistry
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