keyword
MENU ▼
Read by QxMD icon Read
search

3D printing medicine

keyword
https://www.readbyqxmd.com/read/28103751/3d-bioprinting-towards-the-era-of-manufacturing-human-organs-as-spare-parts-for-healthcare-and-medicine
#1
Tanveer Ahmad Mir, Makoto Nakamura
3D printing technology has been used in industrial worlds for decades. 3D bioprinting has recently received an increasing attention across the globe among researchers, academicians, students and even the ordinary people. This emerging technique has a great potential to engineer highly organized functional bioconstructs with complex geometries and tailored components for engineering bio-artificial tissues/organs for widespread applications, including transplantation, therapeutic investigation, drug development, bioassay and disease modelling...
January 19, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/28078628/3d-printed-drugs-for-children-are-we-ready-yet
#2
REVIEW
Maren Preis, Heidi Öblom
The first medicine manufactured by three-dimensional (3D) printing was recently approved by the Food and Drug Administration (FDA). The advantages of printing as a manufacturing route enabling more flexibility regarding the dose, and enlarging individual treatment options, have been demonstrated. There is a particular need for flexible drug delivery solutions when it comes to children. Printing as a new pharmaceutical manufacturing technology brings manufacturing closer to the patient and can easily be adjusted to the required dosing scheme, offering more flexibility for treatments...
January 11, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28067628/3d-bioprinting-improving-in-vitro-models-of-metastasis-with-heterogeneous-tumor-microenvironments
#3
REVIEW
Jacob L Albritton, Jordan S Miller
Even with many advances in treatment over the past decades, cancer still remains a leading cause of death worldwide. Despite the recognized relationship between metastasis and increased mortality rate, surprisingly little is known about the exact mechanism of metastatic progression. Currently available in vitro models cannot replicate the three-dimensionality and heterogeneity of the tumor microenvironment sufficiently to recapitulate many of the known characteristics of tumors in vivo Our understanding of metastatic progression would thus be boosted by the development of in vitro models that could more completely capture the salient features of cancer biology...
January 1, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28017869/endosteal-like-extracellular-matrix-expression-on-melt-electrospun-written-scaffolds
#4
Maria Lourdes Muerza-Cascante, Ali Shokoohmand, Kiarash Khosrotehrani, David Haylock, Paul D Dalton, Dietmar W Hutmacher, Daniela Loessner
: Tissue engineering technology platforms constitute a unique opportunity to integrate cells and extracellular matrix (ECM) proteins into scaffolds and matrices that mimic the natural microenvironments in vitro. The developments of tissue-engineered 3D models that mimic the endosteal microenvironment enable researchers to discover the causes and improve treatments for blood and immune-related diseases. The aim of this study was to establish a physiologically relevant in vitro model using 3D printed scaffolds to assess the contribution of human cells to the formation of a construct that mimics human endosteum...
December 22, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/28008429/applications-of-patient-specific-3d-printing-in-medicine
#5
Martin Heller, Heide-Katharina Bauer, Elisabeth Goetze, Matthias Gielisch, Klaus E Roth, Philipp Drees, Gerrit S Maier, Bernhard Dorweiler, Ahmed Ghazy, Meik Neufurth, Werner E G Müller, Heinz C Schröder, Xiaohong Wang, Christian-Friedrich Vahl, Bilal Al-Nawas
Already three decades ago, the potential of medical 3D printing (3DP) or rapid prototyping for improved patient treatment began to be recognized. Since then, more and more medical indications in different surgical disciplines have been improved by using this new technique. Numerous examples have demonstrated the enormous benefit of 3DP in the medical care of patients by, for example, planning complex surgical interventions preoperatively, reducing implantation steps and anesthesia times, and helping with intraoperative orientation...
2016: International Journal of Computerized Dentistry
https://www.readbyqxmd.com/read/28008428/materials-and-scaffolds-in-medical-3d-printing-and-bioprinting-in-the-context-of-bone-regeneration
#6
Martin Heller, Heide-Katharina Bauer, Elisabeth Goetze, Matthias Gielisch, Ibrahim T Ozbolat, Kazim K Moncal, Elias Rizk, Hermann Seitz, Michael Gelinsky, Heinz C Schröder, Xiaohong H Wang, Werner E G Müller, Bilal Al-Nawas
The structural and functional repair of lost bone is still one of the biggest challenges in regenerative medicine. In many cases, autologous bone is used for the reconstruction of bone tissue; however, the availability of autologous material is limited, which always means additional stress to the patient. Due to this, more and more frequently various biocompatible materials are being used instead for bone augmentation. In this context, in order to ensure the structural function of the bone, scaffolds are implanted and fixed into the bone defect, depending on the medical indication...
2016: International Journal of Computerized Dentistry
https://www.readbyqxmd.com/read/28008427/social-and-legal-frame-conditions-for-3d-and-bioprinting-in-medicine
#7
Heide-Katharina Bauer, Martin Heller, Matthias Fink, Daniela Maresch, Johannes Gartner, Ulrich M Gassner, Bilal Al-Nawas
The beginnings of three-dimensional (3D) printing and bioprinting can be traced to as early as 1984. From printing inorganic models for the generation of biologic scaffolds, additive manufacturing (AM) developed to the direct printing of organic materials, including specialized tissues, proteins, and cells. In recent years, these technologies have gained significantly in relevance, and there have been several innovations, especially in the field of regenerative medicine. It is becoming increasingly important to consider the economic and social aspects of AM, particularly in education and information of medical human resources, society, and politics, as well as for the establishment of homogenous, globally adapted legal regulations...
2016: International Journal of Computerized Dentistry
https://www.readbyqxmd.com/read/28008426/editorial-3d-printing-in-medicine-promise-or-reality
#8
Bilal Al-Nawas
No abstract text is available yet for this article.
2016: International Journal of Computerized Dentistry
https://www.readbyqxmd.com/read/27997104/direct-write-fabrication-of-4d-active-shape-changing-structures-based-on-a-shape-memory-polymer-and-its-nanocomposite
#9
Hongqiu Wei, Qiwei Zhang, Yongtao Yao, Liwu Liu, Yanju Liu, Jinsong Leng
Four-dimensional (4D) active shape-changing structures based on shape memory polymers (SMPs) and shape memory nanocomposites (SMNCs) are able to be controlled in both space and time and have attracted increasing attention worldwide. However, conventional processing approaches have restricted the design space of such smart structures. Herein, 4D active shape-changing architectures in custom-defined geometries exhibiting thermally and remotely actuated behaviors are achieved by direct-write printing of ultraviolet (UV) cross-linking poly(lactic acid)-based inks...
December 20, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27995203/barofuse-a-novel-pressure-driven-adjustable-throughput-perfusion-system-for-tissue-maintenance-and-assessment
#10
Austin Rountree, Amit Karkamkar, Gamal Khalil, Albert Folch, Daniel L Cook, Ian R Sweet
OBJECTIVES: Microfluidic perfusion systems are used for assessing cell and tissue function while assuring cellular viability. Low perfusate flow rates, desired both for conserving reagents and for extending the number of channels and duration of experiments, conventionally depend on peristaltic pumps to maintain flow yet such pumps are unwieldy and scale poorly for high-throughput applications requiring 16 or more channels. The goal of the study was to develop a scalable multichannel microfluidics system capable of maintaining and assessing kinetic responses of small amounts of tissue to drugs or changes in test conditions...
December 2016: Heliyon
https://www.readbyqxmd.com/read/27918636/4d-printing-of-shape-memory-based-personalized-endoluminal-medical-devices
#11
Matt Zarek, Nicola Mansour, Shir Shapira, Daniel Cohn
The convergence of additive manufacturing and shape-morphing materials is promising for the advancement of personalized medical devices. The capability to transform 3D objects from one shape to another, right off the print bed, is known as 4D printing. Shape memory thermosets can be tailored to have a range of thermomechanical properties favorable to medical devices, but processing them is a challenge because they are insoluble and do not flow at any temperature. This study presents here a strategy to capitalize on a series of medical imaging modalities to construct a printable shape memory endoluminal device, exemplified by a tracheal stent...
December 5, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/27917823/3d-bioprinting-of-functional-human-skin-production-and-in-vivo-analysis
#12
Nieves Cubo, Marta Garcia, Juan F Del Cañizo, Diego Velasco, Jose L Jorcano
Significant progress has been made over the past 25 years in the development of in vitro-engineered substitutes that mimic human skin, either to be used as grafts for the replacement of lost skin, or for the establishment of in vitro human skin models. In this sense, laboratory-grown skin substitutes containing dermal and epidermal components offer a promising approach to skin engineering. In particular, a human plasma-based bilayered skin generated by our group, has been applied successfully to treat burns as well as traumatic and surgical wounds in a large number of patients in Spain...
December 5, 2016: Biofabrication
https://www.readbyqxmd.com/read/27906687/economic-3d-printing-approach-for-transplantation-of-human-stem-cell-derived-%C3%AE-like-cells
#13
Jiwon Song, Jeffrey R Millman
Transplantation of human pluripotent stem cells (hPSC) differentiated into insulin-producing β cells is a regenerative medicine approach being investigated for diabetes cell replacement therapy. This report presents a multifaceted transplantation strategy that combines differentiation into stem cell-derived β (SC-β) cells with 3D printing. By modulating the parameters of a low-cost 3D printer, we created a macroporous device composed of polylactic acid (PLA) that houses SC-β cell clusters within a degradable fibrin gel...
December 1, 2016: Biofabrication
https://www.readbyqxmd.com/read/27898010/applications-of-alginate-based-bioinks-in-3d-bioprinting
#14
REVIEW
Eneko Axpe, Michelle L Oyen
Three-dimensional (3D) bioprinting is on the cusp of permitting the direct fabrication of artificial living tissue. Multicellular building blocks (bioinks) are dispensed layer by layer and scaled for the target construct. However, only a few materials are able to fulfill the considerable requirements for suitable bioink formulation, a critical component of efficient 3D bioprinting. Alginate, a naturally occurring polysaccharide, is clearly the most commonly employed material in current bioinks. Here, we discuss the benefits and disadvantages of the use of alginate in 3D bioprinting by summarizing the most recent studies that used alginate for printing vascular tissue, bone and cartilage...
November 25, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27875945/three-dimensional-printing-articular-cartilage-recapitulating-the-complexity-of-native-tissue
#15
Ting Guo, Josephine Lembong, Lijie Grace Zhang, John P Fisher
In the past few decades, the field of tissue engineering combined with rapid prototyping (RP) techniques has been successful in creating biological substitutes that mimic tissues. Its applications in regenerative medicine have drawn efforts in research from various scientific fields, diagnostics, and clinical translation to therapies. While some areas of therapeutics are well developed, such as skin replacement, many others such as cartilage repair can still greatly benefit from tissue engineering and RP due to the low success and/or inefficiency of current existing, often surgical treatments...
December 27, 2016: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/27785150/applications-of-3d-printing-in-healthcare
#16
Helena Dodziuk
3D printing is a relatively new, rapidly expanding method of manufacturing that found numerous applications in healthcare, automotive, aerospace and defense industries and in many other areas. In this review, applications in medicine that are revolutionizing the way surgeries are carried out, disrupting prosthesis and implant markets as well as dentistry will be presented. The relatively new field of bioprinting, that is printing with cells, will also be briefly discussed.
September 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/27784251/review-application-of-fused-deposition-modelling-fdm-method-of-3d-printing-in-drug-delivery
#17
Jingjunjiao Long, Hamideh Gholizadeh, Jun Lu, Craig Bunt, Ali Seyfoddin
Three-dimensional (3D) printing is an emerging manufacturing technology for biomedical and pharmaceutical applications. Fused deposition modelling (FDM) is a low cost extrusion-based 3D printing technique that can deposit materials layer-by-layer to create solid geometries. This review article aims to provide an overview of FDM based 3D printing application in developing new drug delivery systems. The principle methodology, suitable polymers and important parameters in FDM technology and its applications in fabrication of personalised tablets and drug delivery devices are discussed in this review...
October 26, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27776880/guided-autotransplantation-of-teeth-a-novel-method-using-virtually-planned-3-dimensional-templates
#18
Georg D Strbac, Albrecht Schnappauf, Katharina Giannis, Michael H Bertl, Andreas Moritz, Christian Ulm
INTRODUCTION: The aim of this study was to introduce an innovative method for autotransplantation of teeth using 3-dimensional (3D) surgical templates for guided osteotomy preparation and donor tooth placement. METHODS: This report describes autotransplantation of immature premolars as treatment of an 11-year-old boy having suffered severe trauma with avulsion of permanent maxillary incisors. This approach uses modified methods from guided implant surgery by superimposition of Digital Imaging and Communications in Medicine files and 3D data sets of the jaws in order to predesign 3D printed templates with the aid of a fully digital workflow...
December 2016: Journal of Endodontics
https://www.readbyqxmd.com/read/27770218/3d-cell-culturing-and-possibilities-for-myometrial-tissue-engineering
#19
Minoo Heidari Kani, Eng-Cheng Chan, Roger C Young, Trent Butler, Roger Smith, Jonathan W Paul
Research insights into uterine function and the mechanisms of labour have been hindered by the lack of suitable animal and cellular models. The use of traditional culturing methods limits the exploration of complex uterine functions, such as cell interactions, connectivity and contractile behaviour, as it fails to mimic the three-dimensional (3D) nature of uterine cell interactions in vivo. Animal models are an option, however, use of these models is constrained by ethical considerations as well as translational limitations to humans...
October 21, 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/27733894/3d-printed-auto-mixing-chip-enables-rapid-smartphone-diagnosis-of-anemia
#20
Kimberly Plevniak, Matthew Campbell, Timothy Myers, Abby Hodges, Mei He
Clinical diagnosis requiring central facilities and site visits can be burdensome for patients in resource-limited or rural areas. Therefore, development of a low-cost test that utilizes smartphone data collection and transmission would beneficially enable disease self-management and point-of-care (POC) diagnosis. In this paper, we introduce a low-cost iPOC(3D) diagnostic strategy which integrates 3D design and printing of microfluidic POC device with smartphone-based disease diagnosis in one process as a stand-alone system, offering strong adaptability for establishing diagnostic capacity in resource-limited areas and low-income countries...
September 2016: Biomicrofluidics
keyword
keyword
94673
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"