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https://www.readbyqxmd.com/read/29045985/entry-of-medical-school-graduates-into-family-medicine-residencies-2016-2017
#1
Stanley M Kozakowski, Alexandra Travis, Julie P Marcinek, Ashley Bentley, Gerald T Fetter
This annual report is an expansion on previous reports in this series that provides further evidence that the current medical school system is failing, collectively, to produce the primary care workforce that is needed to achieve optimal health in the United States. Inclusion of data on the performance of DO-granting and international medical schools, creates a more complete and complex picture of the contribution of all medical school types to the primary care workforce that should allow stakeholders to set goals, identify institutions with models from which to learn, and develop strategies for continuous improvement...
October 2017: Family Medicine
https://www.readbyqxmd.com/read/29045875/the-effect-of-solutes-on-the-temperature-of-miscibility-transitions-in-multicomponent-membranes
#2
David W Allender, M Schick
We address questions posed by experiments that show small-chain alcohols reduce the miscibility transition temperature when added to giant plasma membrane vesicles (GPMVs), but increase that temperature when added to giant unilamellar vesicles. In giant unilamellar vesicles the change in temperature displays a definite minimum, between decanol and tetradecanol, as a function of alcohol chain length; in GPMVs there is no such minimum. To emphasize the competition between internal entropies of the components and the interactions between them, we model the system as consisting of three different linear polymers...
October 17, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/29044874/information-processing-from-the-motor-cortices-to-the-subthalamic-nucleus-and-globus-pallidus-and-their-somatotopic-organizations-revealed-electrophysiologically-in-monkeys
#3
Hirokazu Iwamuro, Yoshihisa Tachibana, Yoshikazu Ugawa, Nobuhito Saito, Atsushi Nambu
To understand how the information derived from different motor cortical areas representing different body parts is organized in the basal ganglia, we examined the neuronal responses in the subthalamic nucleus (STN), and the external (GPe) and internal (GPi) segments of the globus pallidus, input, relay, and output nuclei, respectively, to stimulation of the orofacial, forelimb, and hindlimb regions of the primary motor cortex (MI) and supplementary motor area (SMA) in macaque monkeys under awake state. Most STN and GPe/GPi neurons responded exclusively to stimulation of either the MI or SMA, and one-fourth to one-third of neurons responded to both...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29044302/functional-ability-in-younger-and-older-elderlies-after-discharge-from-the-intensive-care-unit-a-prospective-cohort
#4
Camila Dietrich, Juliana Rezende Cardoso, Fernanda Vargas, Evelin Carneiro Sanchez, Francine Hoffmann Dutra, Cátia Moreira, Marina Bessel, Caroline Robinson, Maicon Falavigna, Cassiano Teixeira
OBJECTIVE: To compare the functional capacity of younger elderly individuals (60 to 79 years old) with that of older elderly individuals (≥ 80 years old) during the first 6 months after discharge from the intensive care unit. METHODS: A multicenter prospective cohort study was conducted, in which data on intensive care unit admission and outcomes after hospital discharge (immediate post-discharge, after 3 months and after 6 months) were collected. Muscle strength was evaluated through the protocol of the Medical Research Council and dynamometry (handgrip); the ability to perform activities of daily life and functional independence were assessed by the Barthel index and the usual level of physical activity (International Physical Activity Questionnaire); and quality of life was assessed by the 12-Item Short-Form Health Survey Version 2...
July 2017: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/29042389/what-s-up-doc-a-national-cross-sectional-study-of-psychological-wellbeing-of-hospital-doctors-in-ireland
#5
Blánaid Hayes, Lucia Prihodova, Gillian Walsh, Frank Doyle, Sally Doherty
OBJECTIVES: To measure levels of psychological distress, psychological wellbeing and self-stigma in hospital doctors in Ireland. DESIGN: National cross-sectional study of randomised sample of hospital doctors. Participants provided sociodemographic data (age, sex, marital status), work grade (consultant, higher/basic specialist trainee), specialty and work hours and completed well-being questionnaires (the Depression Anxiety Stress Scale, WHO Well-being Index, General Health Questionnaire) and single-item scales on self-rated health and self-stigma...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29042145/electronic-clinical-evaluation-exercise-e-cex-a-new-patient-centered-ehr-use-tool
#6
Maria Alcocer Alkureishi, Wei Wei Lee, Maureen Lyons, Kristen Wroblewski, Jeanne M Farnan, Vineet M Arora
INTRODUCTION: Electronic Health Record (EHR) use can enhance or weaken patient-provider communication. Despite EHR adoption, no validated tool exists to assess EHR communication skills. We aimed to develop and validate such a tool. METHODS: Electronic-Clinical Evaluation Exercise (e-CEX) is a 10-item-tool based on systematic literature review and pilot-testing. Second-year (MS2s) students participated in an EHR-use lecture and structured Clinical Examination (OSCE)...
October 10, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29041982/costs-related-to-cardiac-arrest-management-a-systematic-review-protocol
#7
Guillaume Geri, Joshua Gilgan, Carolyn Ziegler, Wanrudee Isaranuwatchai, Laurie J Morrison
BACKGROUND: Each year, about 500,000 people suffer a cardiac arrest (either out-of-hospital or in-hospital) in the USA. Although significant improvements in survival have occurred through the implementation of complex high-quality protocols of care, global costs related to such management are not clearly described. METHODS: We will undertake a systematic review of the published literature on costs related to the acute phase of cardiac arrest management (from collapse to hospital discharge)...
October 17, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29038898/molecular-and-immunological-characterisation-of-tropomyosin-from-anisakis-pegreffii
#8
Abdouslam Asnoussi, Ibukun E Aibinu, Robin B Gasser, Andreas L Lopata, Peter M Smooker
Tropomyosin (TM) is a major allergen in shellfish, known to cross-react with mite, cockroach and/or some roundworm (nematode) TM. In this study, we aimed to express and purify TM from the parasitic nematode Anisakis pegreffii and also to characterise its cross-reactivity with TM from shellfish. A. pegreffii was isolated from the flathead tiger fish (Neoplatycephalus richardsoni) and characterised using single-strand conformation polymorphism (SSCP)-based sequencing of the first and second internal transcribed spacers (ITS-1 and ITS-2) of nuclear ribosomal DNA...
October 16, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29038687/mental-health-status-of-north-korean-refugees-in-south-korea-and-risk-and-protective-factors-a-10-year-review-of-the-literature
#9
REVIEW
Yeeun Lee, Minji Lee, Subin Park
Background: North Korean refugees (NKRs) are often exposed to traumatic events in North Korea and during their defection. Furthermore, they face sociocultural barriers in adapting to the new society to which they have defected. Objective: To integrate previous findings on this mentally vulnerable population, we systematically reviewed articles on the mental health of NKRs in South Korea. Method: We searched for empirical studies conducted in the last 10 years in six online databases (international journals: Embase, PubMed, Scopus, Web of Science; Korean journals: DBPIA, KMbase) through June 2017...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29038184/optimising-the-quality-of-antibiotic-prescribing-in-out-of-hours-primary-care-in-belgium-a-study-protocol-for-an-action-research-project
#10
Annelies Colliers, Samuel Coenen, Hilde Philips, Roy Remmen, Sibyl Anthierens
INTRODUCTION: Antimicrobial resistance is a major public health threat driven by inappropriate antibiotic use, mainly in general practice and for respiratory tract infections. In Belgium, the quality of general practitioners' (GPs) antibiotic prescribing is low. To improve antibiotic use, we need a better understanding of this quality problem and corresponding interventions. A general practitioners cooperative (GPC) for out-of-hours (OOH) care presents a unique opportunity to reach a large group of GPs and work on quality improvement...
October 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29038046/multiple-reversals-of-strand-asymmetry-in-molluscs-mitochondrial-genomes-and-consequences-for-phylogenetic-inferences
#11
Shao'e Sun, Qi Li, Lingfeng Kong, Hong Yu
Strand asymmetry in nucleotide composition is a remarkable feature of animal mitochondrial genomes. The strand-specific bias in the nucleotide composition of the mtDNA has been known to be highly problematic for phylogenetic analyses. Here, the strand asymmetry was compared across 140 mollusc species and analyzed for a mtDNA fragment including twelve protein-coding genes. The analyses show that almost all species in Gastropoda (except Heterobranchia) and all species in Bivalvia present reversals of strand bias...
October 13, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/29037645/postural-insoles-on-gait-in-children-with-cerebral-palsy-randomized-controlled-double-blind-clinical-trial
#12
Hugo Pasin Neto, Luanda André Collange Grecco, Luis Alfredo Braun Ferreira, Natália Almeida Carvalho Duarte, Manuela Galli, Claudia Santos Oliveira
The aim of the present study was to assess the effect of postural insoles on gait performance in children with Cerebral Palsy (CP). Twenty four children between four and 12 years of age were randomly allocated either the control group (n = 12) or experimental group (n = 12). The control group used placebo insoles and the experimental group used postural insoles. Three-dimensional gait analysis was performed under three conditions: barefoot, in shoes and in shoes with insoles. Three evaluations were carried out: 1)immediately following placement of the insoles; 2)after three months of insole use; and 3)one month after suspending insole use...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29036756/acupuncture-or-acupressure-for-induction-of-labour
#13
REVIEW
Caroline A Smith, Mike Armour, Hannah G Dahlen
BACKGROUND: This is one of a series of reviews of methods of cervical ripening and labour induction. The use of complementary therapies is increasing. Women may look to complementary therapies during pregnancy and childbirth to be used alongside conventional medical practice. Acupuncture involves the insertion of very fine needles into specific points of the body. Acupressure is using the thumbs or fingers to apply pressure to specific points. The limited observational studies to date suggest acupuncture for induction of labour has no known adverse effects to the fetus, and may be effective...
October 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29035132/hybrid-lipid-polymer-nanoparticles-for-pulmonary-delivery-of-sirna-development-and-fate-upon-in-vitro-deposition-on-the-human-epithelial-airway-barrier
#14
Ivana d'Angelo, Gabriella Costabile, Estelle Durantie, Paola Brocca, Valeria Rondelli, Annapina Russo, Giulia Russo, Agnese Miro, Fabiana Quaglia, Alke Petri-Fink, Barbara Rothen-Rutishauser, Francesca Ungaro
BACKGROUND: Nowadays, the downregulation of genes involved in the pathogenesis of severe lung diseases through local siRNA delivery appears an interesting therapeutic approach. In this study, we propose novel hybrid lipid-polymer nanoparticles (hNPs) consisting of poly(lactic-co-glycolic) acid (PLGA) and dipalmitoyl phosphatidylcholine (DPPC) as siRNA inhalation system. METHODS: A panel of DPPC/PLGA hNPs was prepared by emulsion/solvent diffusion and fully characterized...
October 16, 2017: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/29033118/physical-activity-stigma-and-quality-of-life-in-patients-with-epilepsy
#15
Gloria Maria Almeida Souza Tedrus, Guilherme Sabbag Sterca, Renato Buarque Pereira
Indication of physical activity (PA) for people with epilepsy (PWE) is debatable. This study investigated whether the International Physical Activity Questionnaire (IPAQ) score is related to the clinical aspects of epilepsy, QOLIE-31, and the Stigma Scale of Epilepsy (SSE) score of 67 PWE at a significance level of 5% (p<0.05). About one-third (32.8%) of the PWE were sedentary/irregularly active. Lower QOLIE-31 scores and higher SSE scores were found in PWE who did not practice PA for fear of seizures and in sedentary/irregularly active PWE...
October 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29031468/gunslingers-poker-players-and-chickens-1-decision-making-under-physical-performance-pressure-in-elite-athletes
#16
Beth L Parkin, Katie Warriner, Vincent Walsh
BACKGROUND: The cognitive skills required during sport are highly demanding; accurate decisions based on the processing of dynamic environments are made in a fraction of a second (Walsh, 2014). Optimal decision-making abilities are crucial for success in sporting competition (Bar-Eli et al., 2011; Kaya, 2014). Moreover, for the elite athlete, decision making is required under conditions of intense mental and physical pressure (Anshel and Wells, 2000), yet much of the work in this area has largely ignored the highly stressful context in which athletes operate...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/29029258/acupuncture-improves-peri-menopausal-insomnia-a-randomized-controlled-trial
#17
Fu Cong, Zhao Na, Liu Zhen, Yuan Lu-Hua, Xie Chen, Yang Wen-Jia, Yu Xin-Tong, Yu Huan, Chen Yun-Fei
Study Objective: To evaluate the short-term efficacy of acupuncture for the treatment of peri-menopausal insomnia (PMI). Methods: Design: A randomized, participant-blind, placebo-controlled trial consisted of the acupuncture group (n=38) and placebo-acupuncture group (n=38). Setting: A tertiary teaching and general hospital. Participants: 76 peri-menopausal women with insomnia disorder based on the International Classification of Sleep Disorders, third Edition. Interventions: A 10-session of acupuncture at bilateral Shenshu (BL 23) and Ganshu (BL 18) with unilateral Qimen (LR 14) and Jingmen (GB 25) or Streitberger needles at the same acupoints was performed for over 3 weeks...
September 22, 2017: Sleep
https://www.readbyqxmd.com/read/29028112/the-role-of-declining-adaptive-homeostasis-in-ageing
#18
Laura C D Pomatto, Kelvin J A Davies
Adaptive homeostasis is, 'the transient expansion or contraction of the homeostatic range for any given physiological parameter in response to exposure to sub-toxic, non-damaging, signalling molecules or events, or the removal or cessation of such molecules or events (Davies, 2016a)." Adaptive homeostasis enables biological systems to make continuous short-term adjustments for optimal functioning despite ever-changing internal and external environments. Initiation of adaptation in response to an appropriate signal allows organisms to successfully cope with much greater, normally toxic, stresses...
October 13, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29025723/setting-the-stage-for-2018-how-the-changes-in-the-american-joint-committee-on-cancer-union-for-international-cancer-control-cancer-staging-manual-eighth-edition-impact-radiologists
#19
C M Glastonbury, S K Mukherji, B O'Sullivan, W M Lydiatt
The updated eighth edition of the Cancer Staging Manual of the American Joint Committee on Cancer will be implemented in January 2018. There are multiple changes to the head and neck section of the manual, which will be relevant to radiologists participating in multidisciplinary head and neck tumor boards and reading pretreatment head and neck cancer scans. Human papillomavirus-related/p16(+) oropharyngeal squamous cell carcinoma will now be staged separately; this change reflects the markedly better prognosis of these tumors compared with non-human papillomavirus/p16(-) oropharyngeal squamous cell carcinoma...
October 12, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29025452/management-of-failed-spinal-anaesthesia-for-caesarean-section
#20
Gavin Wyndham Jones, Raphael Anthony Samuel, Bruce McClure Biccard
BACKGROUND: Failed spinal anaesthesia for caesarean section (CS) may be partial or complete and the subsequent discomfort is the most commonly cited cause of litigation in obstetric anaesthesia. OBJECTIVES: To determine if there is a standardised approach to: (i) testing the level of block of spinal anaesthesia; and (ii) the management of failed spinal anaesthesia for CS. METHODS: A structured questionnaire to ascertain the current practice of testing the level of block and management of three different scenarios of failed spinal anaesthesia was distributed to 51 government hospitals in KwaZulu-Natal, South Africa (SA)...
June 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
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