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https://www.readbyqxmd.com/read/29458200/influence-of-treatment-modality-on-morbidity-and-mortality-in-periprosthetic-femoral-fracture-a-comparative-study-of-71-fractures-treated-by-internal-fixation-or-femoral-implant-revision
#1
S Cohen, X Flecher, S Parratte, M Ollivier, J N Argenson
INTRODUCTION: The incidence of periprosthetic femoral fracture is constantly increasing, with high associated morbidity and mortality. Surgical treatment is guided by the Vancouver classification, but the influence of type of treatment on morbidity and mortality has been little analyzed. The theoretic advantage of implant revision over internal fixation is that it should allow earlier weight-bearing, although the impact of this on morbidity and mortality and autonomy has not been demonstrated...
February 16, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29456193/changes-in-shoulder-girdle-strength-in-3-consecutive-years-in-elite-adolescent-swimmers-a-longitudinal-cohort-study
#2
Fernanda A P Habechian, Kim Van Malderen, Paula R Camargo, Ann M Cools
BACKGROUND: The shoulder complex is highly loaded during swimming. No studies were found analyzing the changes in shoulder girdle strength in young swimmers, through the years. OBJECTIVE: To analyze the changes in strength of internal rotators and external rotators of the arm, lower trapezius and supraspinatus and in the external rotators/internal rotators ratio in young elite swimmers through 3 years. METHODS: 31 adolescent elite swimmers (14-18 years, of both sexes) participated in the study...
February 6, 2018: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29456040/a-very-rare-case-of-renal-cell-carcinoma-metastasis-to-spermatic-cord-and-a-condensed-literature-review
#3
Ioannis Tsouknidas, Nikolaos Tasis, Charalambos Kokkinos, Helen Trihia, Dimitrios Filippou, Panagiotis Skandalakis, Theodoros Troupis
INTRODUCTION: Renal cell carcinoma (RCC) is proved to be the ninth most common malignancy. Two-third of the patients suffering from RCC will present metastases. Secondary metastases of RCC to spermatic cord are very rare. PRESENTATION OF CASE: In this report we present the case of a patient with renal cell carcinoma with metachronous metastasis to the spermatic cord occurring two years after the initial diagnosis of the disease. DISCUSSION: Our patient was treated according to EAU guidelines...
December 26, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29455555/employment-status-is-related-to-sleep-problems-in-adults-with-autism-spectrum-disorder-and-no-comorbid-intellectual-impairment
#4
Emma K Baker, Amanda L Richdale, Agnes Hazi
Both sleep problems and unemployment are common in adults with autism spectrum disorder; however, little research has explored this relationship in this population. This study aimed to explore factors that may be associated with the presence of an International Classification of Sleep Disorders-Third Edition defined sleep disorder in adults with autism spectrum disorder (IQ > 80). A total of 36 adults with autism spectrum disorder and 36 controls were included in the study. Participants completed a 14-day actigraphy assessment and questionnaire battery...
February 1, 2018: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29455458/diagnosis-presentation-and-initial-severity-of-autoimmune-hepatitis-aih-in-patients-attending-28-hospitals-in-the-uk
#5
Victoria Gordon, Ratul Adhikary, Victoria Appleby, Debasis Das, James Day, Toby Delahooke, Selena Dixon, David Elphick, Claire Hardie, Barbara Hoeroldt, Patricia Hooper, John Hutchinson, Rebecca Jones, Faisal Khan, Guruprasad P Aithal, John McGonigle, Andrew Nelson, Alick Nkhoma, Stavroula Pelitari, Martin Prince, Annell Prosser, Vinay Sathanarayana, Sophia Savva, Naina Shah, Sushma Saksena, Sreedhari Thayalasekaran, Deven Vani, Andrew Yeoman, Dermot Gleeson
BACKGROUND AND AIMS: There is limited information regarding patients with AIH outside relatively few large centres. We describe here the presenting features of patients with AIH, collected as part of an audit involving 28 UK hospitals. METHODS: Patients (incident since 1/1/2007 or prevalent since 1/1/2000) were >18 years and either met 1999 International AIH Group (IAIHG) diagnostic criteria (n=1164), or received immunosuppressive therapy for clinically diagnosed AIH (n=103)...
February 17, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29455344/lower-third-molar-displaced-to-lateral-pharyngeal-space-after-mandibular-angle-fracture-a-case-report
#6
Rodrigo Dos Santos Pereira, Jonathan Ribeiro da Silva, João Paulo Bonardi, Eduardo Hochuli-Vieira
The removal of displaced dental elements from deep anatomical spaces is a condition that requires the knowledge of the region and skills to perform the procedure. The lateral pharyngeal space contains important structures such as the internal carotid artery and close proximity with the cranium basis. The aim of this paper is to report a clinical case of a lower third molar displaced to the lateral pharyngeal space after a mandibular angle fracture and its treatment by surgical intervention. The tooth was removed under general anesthesia by direct approach and the fracture was reduced and fixed with a plate and screws...
February 18, 2018: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29455310/germans-learn-how-to-save-lives-a-nationwide-cpr-education-initiative
#7
Manuela Malsy, Richard Leberle, Bernhard Graf
BACKGROUND: Sudden cardiac death is one of the most frequent causes of death in Germany and the third leading cause of death in the industrialized world. Yet, the percentage of people providing first aid in the case of sudden cardiac arrest in Germany is alarmingly low by international comparison. Training Germans or reminding them of the simple but effective steps of resuscitation, so that everybody can save a live in an emergency. METHODS: For the campaign 'Resuscitation Week', physicians and paramedics trained passers-by in cardiovascular resuscitation free of charge...
February 17, 2018: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29455119/developing-a-safety-heatmap-of-uncontrolled-intersections-using-both-conflict-probability-and-severity
#8
Yingying Ma, Xiaoran Qin, Offer Grembek, Zhiwei Chen
This paper presents a method to assess the safety of uncontrolled intersections considering two major properties of traffic conflicts-conflict probability and severity. This method assesses both the safety level of the entire intersection in addition to the distribution of safety within it. Intersections are modeled by a two-dimensional Cartesian coordinate system and the internal space of intersections is divided into cells. First, the vehicle movement characteristics of an uncontrolled intersection are modeled...
February 15, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29454807/characterization-of-chronic-obstructive-pulmonary-disease-prescribing-patterns-in-the-united-states
#9
Sarah Petite
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the third-leading cause of death in the United States. Guideline recommendations for medication therapy include the use of inhaled medications for management of stable COPD. There are limited data available describing prescribing percentages of medications in patients with COPD. AIM: To determine the prescribing percentages of medications for COPD in a national, cross-sectional study. METHODS: This was a national, cross-sectional study using data from the National Ambulatory Medical Care Survey (NAMCS) in 2013...
February 15, 2018: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29454739/spanish-and-catalan-translation-cultural-adaptation-and-validation-of-the-picker-patient-experience-questionnaire-15
#10
M J Bertran, M Viñarás, M Salamero, F Garcia, C Graham, A McCulloch, J Escarrabill
OBJECTIVE: To develop and test a culturally adapted core set of questions to measure patients' experience after in-patient care. MATERIAL AND METHODS: Following the methodology recommended by international guides, a basic set of patient experience questions, selected from Picker Institute Europe questionnaires (originally in English), was translated to Spanish and Catalan. Acceptability, construct validity and reliability of the adapted questionnaire were assessed via a cross-sectional validation study...
February 14, 2018: Revista de Calidad Asistencial: Organo de la Sociedad Española de Calidad Asistencial
https://www.readbyqxmd.com/read/29454194/diagnostic-and-treatment-services-for-patients-with-psychogenic-nonepileptic-seizures-pnes-a-survey-of-health-professionals-in-urban-china
#11
Xin Tong, Dongmei An, Markus Reuber, Qin Zhang, Dong Zhou
PURPOSE: This study is intended to provide an overview of diagnostic and treatment services for patients with psychogenic nonepileptic seizures (PNES) across China. METHODS: Using a questionnaire devised by the PNES Task Force of Neuropsychiatry Commission of the International League Against Epilepsy (ILAE), we conducted a survey among Chinese health professionals at the Sixth Advanced International Course: Clinical Epileptology. Descriptive analyses were performed...
January 31, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29451709/shortcomings-in-the-management-of-undescended-testis-guideline-intention-vs-reality-and-the-underlying-causes-insights-from-the-biggest-german-cohort
#12
Philip Boehme, Berit Geis, Johannes Doerner, Stefan Wirth, Kai O Hensel
OBJECTIVES: To assess the implementation of the current guideline and identify potential underlying causes for late surgery in children with Undescended testis (UDT) in Germany. UDT is the most common surgical issue in paediatric urology. To avoid malignant degeneration and subfertility current guidelines recommend orchidopexy during the first year of life. However, this seems not to be implemented in practice. PATIENTS AND METHODS: 5547 patients with cryptorchidism at 16 hospitals nationwide were studied regarding age at orchidopexy between 2003 and 2016...
February 16, 2018: BJU International
https://www.readbyqxmd.com/read/29449827/sun-exposure-across-the-life-course-significantly-modulates-early-multiple-sclerosis-clinical-course
#13
Steve Simpson, Ingrid van der Mei, Robyn M Lucas, Anne-Louise Ponsonby, Simon Broadley, Leigh Blizzard, Bruce Taylor
Background: Low vitamin D and/or sun exposure have been associated with increased risk of multiple sclerosis (MS) onset. However, comparatively, few studies have prospectively examined associations between these factors and clinical course. Objectives: To evaluate the association of sun exposure parameters and vitamin D levels with conversion to MS and relapse risk in a prospectively monitored cohort of 145 participants followed after a first demyelinating event up to 5-year review (AusLong Study)...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29449171/changes-in-antimicrobial-susceptibility-of-commonly-clinically-significant-isolates-before-and-after-the-interventions-on-surgical-prophylactic-antibiotics-spas-in-shanghai
#14
Su Wang, Li-Zhong Han, Yu-Xing Ni, Yi-Bo Zhang, Qun Wang, Da-Ke Shi, Wen-Hui Li, Yi-Chen Wang, Chen-Rong Mi
Surveillances and interventions on antibiotics use have been suggested to improve serious drug-resistance worldwide. Since 2007, our hospital have proposed many measures for regulating surgical prophylactic antibiotics (carbapenems, third gen. cephalosporins, vancomycin, etc.) prescribing practices, like formulary restriction or replacement for surgical prophylactic antibiotics and timely feedback. To assess the impacts on drug-resistance after interventions, we enrolled infected patients in 2006 (pre-intervention period) and 2014 (post-intervention period) in a tertiary hospital in Shanghai...
February 12, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29448480/quantum-thermodynamics-from-the-nonequilibrium-dynamics-of-open-systems-energy-heat-capacity-and-the-third-law
#15
J-T Hsiang, C H Chou, Y Subaşı, B L Hu
In a series of papers, we intend to take the perspective of open quantum systems and examine from their nonequilibrium dynamics the conditions when the physical quantities, their relations, and the laws of thermodynamics become well defined and viable for quantum many-body systems. We first describe how an open-system nonequilibrium dynamics (ONEq) approach is different from the closed combined system + environment in a global thermal state (CGTs) setup. Only after the open system equilibrates will it be amenable to conventional thermodynamics descriptions, thus quantum thermodynamics (QTD) comes at the end rather than assumed in the beginning...
January 2018: Physical Review. E
https://www.readbyqxmd.com/read/29447109/sepsis-2018-definitions-and-guideline-changes
#16
Lena M Napolitano
BACKGROUND: Sepsis is a global healthcare issue and continues to be the leading cause of death from infection. Early recognition and diagnosis of sepsis is required to prevent the transition into septic shock, which is associated with a mortality rate of 40% or more. DISCUSSION: New definitions for sepsis and septic shock (Third International Consensus Definitions for Sepsis and Septic Shock [Sepsis-3]) have been developed. A new screening tool for sepsis (quick Sequential Organ Failure Assessment [qSOFA]) has been proposed to predict the likelihood of poor outcome in out-of-intensive care unit (ICU) patients with clinical suspicion of sepsis...
February 2018: Surgical Infections
https://www.readbyqxmd.com/read/29445965/traumatic-subarachnoid-hemorrhage-related-to-ophthalmic-artery-avulsion-a-case-report
#17
Alessandro Prior, Luca Allegretti, Ilaria Melloni, Marta Bovio, Francesco Laganà, Marco Ceraudo, Gianluigi Zona
We present a case of ophthalmic artery (OA) traumatic avulsion, leading to a post-traumatic subarachnoid hemorrhage (SAH) with ventricular blood invasion and hydrocephalus, mimicking an internal carotid aneurysm rupture. This is the third case of such an event reported in literature and the first without orbital fractures and optic nerve avulsion. Conservative treatment was sufficient for the avulsion, but surgery was needed for the coexisting eye luxation. Traumatic OA avulsion is a rare but possible event and should be suspected in case of basal cisterns SAH, evidence of orbital trauma and CT angiogram or angiographic absence of opacification of the OA...
February 14, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29445433/upright-catheter-based-cerebral-angiography
#18
Adnan I Qureshi, Muhammad A Saleem, Omer Naveed, Mohtasim A Qureshi, Shawn S Wallery
Background: Several studies using Doppler ultrasound have suggested cerebral venous drainage is through paravertebral venous plexus due to the collapse of internal jugular veins in an upright position. Methods: We present a technique of acquiring venographic images during an upright position as part of catheter-based angiography to provide additional information regarding cerebral venous diseases. Angiographic images in anteroposterior projection were acquired in lying position and after patients were placed at 60° using radiolucent supporting wedges on angiographic table...
December 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/29445311/fetal-growth-restriction-in-rural-bangladesh-a-prospective-study
#19
Farzana Ferdous, Md Harunor Rashid, Enbo Ma, Rubhana Raqib, Hiromi Hamada, Yukiko Wagatsuma
Background: Fetal growth restriction (FGR) and low birth weight(LBW) are serious public health problems. In developing countries, the incidence of low birth weight is predominantly the result of FGR, and both low birth weight and FGR are associated with neonatal death and later growth and development. Fetal growth charts are important for assessing the size of the fetus during pregnancy. The aims of this study were to describe the fetal growth pattern of a population in rural Bangladesh where maternal undernutrition is prevalent and to compare the timing of FGR in that population with WHO and INTERGROWTH- 21st international reference values...
2018: Tropical Medicine and Health
https://www.readbyqxmd.com/read/29444827/site-specific-polyubiquitination-differentially-regulates-parathyroid-hormone-receptor-initiated-mapk-signaling-and-cell-proliferation
#20
Qiangmin Zhang, Kunhong Xiao, Hongda Liu, Lei Song, Jennifer C McGarvey, W Bruce Sneddon, Alessandro Bisello, Peter A Friedman
G protein-coupled receptor (GPCR) signaling and trafficking are essential for cellular function and regulated by phosphorylation, β-arrestin, and ubiquitination. The GPCR parathyroid hormone receptor (PTHR) exhibits time-dependent reversible ubiquitination. The exact ubiquitination sites in PTHR are unknown, but extend upstream of its intracellular tail. Here, using tandem MS, we identified Lys-388 in the third loop and Lys-484 in the C-terminal tail as primary ubiquitination sites in PTHR. We found that PTHR ubiquitination requires β-arrestin and does not display a preference for β-arrestin1 or 2...
February 14, 2018: Journal of Biological Chemistry
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