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https://www.readbyqxmd.com/read/29765923/insomnia-with-musculoskeletal-pain-in-postmenopause-associations-with-symptoms-mood-and-quality-of-life
#1
Cristina Frange, Helena Hachul, Camila Hirotsu, Sergio Tufik, Monica Levy Andersen
Objectives: To investigate the relationship between insomnia (INS) combined with chronic musculoskeletal pain (MSP) in postmenopausal women and its characteristics regarding MSP, menopausal and mood symptoms, sleep and quality of life (QOL). Methods: A cross-sectional control study in 4 groups of postmenopausal women: control (n = 15), MSP (n = 15), INS (n =15) and INS + MSP (n = 17). Sixty-two participants completed questionnaires and had blood collected, and 43 underwent polysomnography...
April 2018: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/29755029/a-double-blind-placebo-controlled-trial-of-fennel-foeniculum-vulgare-on-menopausal-symptoms-a-high-placebo-response
#2
Masumeh Ghazanfarpour, Mona Najaf Najafi, Nosrat Baharian Sharghi, Mahsa Sadat Mousavi, Masoudeh Babakhanian, Hassan Rakhshanded
OBJECTIVE: The present study aimed to evaluate the oral fennel effects on the menopausal symptoms. MATERIAL AND METHODS: This double-blind, randomized, placebo-controlled trial was conducted on fifty postmenopausal women in Mashhad (Iran). Patients randomly divided into two groups of fennel ( n = 25) and placebo ( n= 25). The measurements were carried out at the baseline and after three months through Menopause-Specific Quality of Life (MENQOL) questionnaire. RESULTS: Both placebo and treatment groups revealed significant improvement in the hot flush score ( p< 0...
May 14, 2018: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/29747982/asthma-over-the-age-of-65-all-s-well-that-ends-well
#3
Alan P Baptist, Paula J Busse
Asthma in older adults (often classified as those 65 years or older) is relatively common, underdiagnosed, and suboptimally treated. It is an important health problem, as the population of the United States continues to age. Unfortunately, asthma morbidity and mortality rates are highest in this age group. Alterations in the innate and adaptive immune responses occur with aging, and contribute to pathophysiologic differences and subsequent treatment challenges. The symptoms of asthma may differ from those in younger populations, and often include fatigue...
May 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29744010/prevention-of-cardiovascular-disease-in-women
#4
REVIEW
Anum Saeed, June Kampangkaew, Vijay Nambi
Cardiovascular diseases are the leading cause of morbidity and mortality among women worldwide. The pathophysiological basis of cardiovascular health among men and women is not identical. This leads to variable cardiovascular responses to stimulus and presentation of cardiovascular disease symptoms, both of which can have a direct effect on treatment outcomes. Traditionally, the enrollment of women in clinical trials has been minimal, resulting in a lack of gender-specific analysis of clinical trial data and, therefore, the absence of concrete risk factor assessment among women...
October 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29739458/anti-stress-effects-of-human-placenta-extract-possible-involvement-of-the-oxidative-stress-system-in-rats
#5
Hyun-Jung Park, Hyun Soo Shim, Sunyoung Lee, Dae Hyun Hahm, Hyejung Lee, Chang Taek Oh, Hae Jung Han, Hyi Jeong Ji, Insop Shim
BACKGROUND: Human placenta hydrolysate (hPH) has been utilized to improve menopausal, fatigue, liver function. Its high concentration of bioactive substances is known to produce including antioxidant, anti-inflammatory and anti-nociceptive activities. However, its mechanisms of stress-induced depression remain unknown. METHODS: The present study examined the effect of hPH on stress-induced depressive behaviors and biochemical parameters in rats. hPH (0.02 ml, 0...
May 8, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29738424/effects-of-vaginal-estradiol-tablets-and-moisturizer-on-menopause-specific-quality-of-life-and-mood-in-healthy-postmenopausal-women-with-vaginal-symptoms-a-randomized-clinical-trial
#6
Susan J Diem, Katherine A Guthrie, Caroline M Mitchell, Susan D Reed, Joseph C Larson, Kristine E Ensrud, Andrea Z LaCroix
OBJECTIVE: Compare the effects of a vaginal estradiol tablet and a vaginal moisturizer, each to placebo, on menopause-related quality of life and mood in postmenopausal women with moderate-severe vulvovaginal symptoms. METHODS: A total of 302 postmenopausal women enrolled in a 12-week, double-blind, placebo-controlled randomized trial were assigned to vaginal 10 μg estradiol tablet plus placebo gel (n = 102), vaginal moisturizer plus placebo tablet (n = 100), or dual placebo (n = 100)...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29738418/anxiety-levels-predict-fracture-risk-in-postmenopausal-women-assessed-for-osteoporosis
#7
Antonino Catalano, Gabriella Martino, Federica Bellone, Agostino Gaudio, Carmen Lasco, Viviana Langher, Antonino Lasco, Nunziata Morabito
OBJECTIVE: There has been increasing interest in the association of psychiatric disorders with fracture risk. This study aimed at investigating the role of severity of anxiety in bone health. METHODS: Multiple clinical risk factors for fractures, the Fracture Risk Assessment Tool score, the bone mineral density (BMD) at the lumbar spine and femoral neck, Hamilton Anxiety Rating Scale (HAMA) scores, Beck Depression Inventory scores, and the 36-Item Short Form Health Survey (SF-36) scores for evaluation of the quality of life were determined, and x-ray vertebral morphometry was carried out in postmenopausal women referred for osteoporosis...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29723767/tibolone-improves-depression-in-women-through-the-menopause-transition-a-double-blind-randomized-controlled-trial-of-adjunctive-tibolone
#8
Jayashri Kulkarni, Emorfia Gavrilidis, Natalie Thomas, Abdul-Rahman Hudaib, Roisin Worsley, Caroline Thew, Caitlin Bleeker, Caroline Gurvich
BACKGROUND: Many women with no past psychiatric history experience severe mood symptoms for the first time in their life during the menopausal transition, with debilitating long-term consequences. Women with a history of depression can experience a relapse or worsening of symptoms during the menopause transition. Traditional antidepressants, SSRIs or SNRIs, are commonly prescribed as the first line response. However, such treatment has shown only small improvements with side effects. Hormone therapies directly targeting the perimenopausal fluctuations in reproductive hormonal systems such as tibolone, have significant potential to treat perimenopausal depression...
April 24, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29721647/cardiac-autonomic-modulation-impairments-in-advanced-breast-cancer-patients
#9
Claudia Arab, Luiz Carlos Marques Vanderlei, Laércio da Silva Paiva, Kyle Levi Fulghum, Carlos Elias Fristachi, Afonso Celso Pinto Nazario, Simone Elias, Luiz Henrique Gebrim, Celso Ferreira Filho, Yori Gidron, Celso Ferreira
AIM: To compare cardiac autonomic modulation in early- versus advanced-stage breast cancer patients before any type of cancer treatment and investigate associated factors. METHODS AND RESULTS: This cross-sectional study included women (30-69 years old) with primary diagnosis of breast cancer and women with benign breast tumors. We evaluated cardiac modulation by heart rate variability and assessed factors of anxiety, depression, physical activity, and other relevant medical variables...
May 2, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29700350/mindfulness-based-stress-reduction-mbsr-or-psychoeducation-for-the-reduction-of-menopausal-symptoms-a-randomized-controlled-clinical-trial
#10
Carmen Wong, Benjamin Hon-Kei Yip, Ting Gao, Kitty Yu Yuk Lam, Doris Mei Sum Woo, Annie Lai King Yip, Chloe Yu Chin, Winnie Pui Yin Tang, Mandy Mun Tse Choy, Katrina Wai Key Tsang, Suzanne C Ho, Helen Shuk Wah Ma, Samuel Yeung Shan Wong
Psychological and behavioural interventions may be effective in reducing menopause-related symptoms. This randomized controlled trial aimed to evaluate the effectiveness of Mindfulness-based Stress Reduction (MBSR) in reducing menopause-related symptoms by comparing with an active control group, the menopause education control (MEC). Symptomatic peri-menopausal and post-menopausal women with mild to moderate symptoms were recruited. The primary outcome was overall menopausal symptoms measured by modified Greene Climacteric Scale (GCS)...
April 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29690858/effects-of-menopausal-symptoms-and-depression-on-the-quality-of-life-of-premenopausal-women-with-breast-cancer-in-korea
#11
Jeong Ae Han, So Young Choi, Seonah Lee
INTRODUCTION: As breast cancer survivors have increased, improving quality of life of the survivors becomes an important issue. The purpose of this study was to examine relationships among menopausal symptoms, depression, and quality of life and to identify the factors affecting the quality of life in premenopausal women with breast cancer. METHOD: This was a descriptive, correlational study using structured questionnaires for 90 premenopausal women with breast cancer attending the outpatient clinic of a tertiary hospital in Korea...
April 1, 2018: Journal of Transcultural Nursing: Official Journal of the Transcultural Nursing Society
https://www.readbyqxmd.com/read/29680438/factors-associated-with-poor-sleep-during-menopause-results-from-the-midlife-women-s-health-study
#12
Rebecca L Smith, Jodi A Flaws, Megan M Mahoney
BACKGROUND: Poor sleep is one of the most common problems reported during menopause, and is known to vary throughout the menopause transition. The objective of this study was to describe the dynamics of poor sleep among participants of the Midlife Women's Health Study and to identify risk factors associated with poor sleep during the menopausal transition. METHODS: Annual responses to surveys that included questions about the frequency of sleep disturbances and insomnia were analyzed to determine the likelihood of persistent poor sleep throughout the menopausal transition and the correlation of responses to the different sleep-related questions, including frequency of restless sleep during the first year of the study...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29673827/menopause-ageing-and-alcohol-use-disorders-in-women
#13
REVIEW
Jelena Milic, Marija Glisic, Trudy Voortman, Laura Pletsch Borba, Eralda Asllanaj, Lyda Z Rojas, Jenna Troup, Jessica C Kiefte-de Jong, Ed van Beeck, Taulant Muka, Oscar H Franco
Alcohol intake affects the female body differently than it affects the male body. This is caused by females' lower levels of dehydrogenase enzymes, the enzyme that breaks down alcohol, coupled with the higher fat/water ratio of the female body. Both these factors cause alcohol levels to rise more quickly after ingestion in women than in men. This makes females more vulnerable to alcohol's harmful effects, and consequently women tend to develop alcohol-related diseases earlier in life than do men. As women age and go through menopause, they experience changes in body composition and life changes like retirement or loss of a loved one...
May 2018: Maturitas
https://www.readbyqxmd.com/read/29672210/prognostic-utility-of-stress-testing-and-cardiac-biomarkers-in-menopausal-women-at-low-to-intermediate-risk-for-coronary-artery-disease-smart-study-5-year-outcome
#14
Sahar S Abdelmoneim, Caroline A Ball, Francesca Mantovani, Mary E Hagen, Susan Eifert-Rain, Susan Wilansky, Ramon Castello, Patricia A Pellikka, Patricia J M Best, Sharon L Mulvagh
BACKGROUND: In women with low to intermediate risk of coronary artery disease (CAD), prognostic detection strategies have been controversial. We present the follow-up data of the SMART trial in peri/postmenopausal women at low to intermediate risk of CAD. OBJECTIVES: To determine the value of contrast stress echocardiography (CSE), stress electrocardiogram (sECG), and serum biomarkers for prediction of cardiovascular events (CE) in peri/postmenopausal women at low to intermediate risk of CAD...
April 19, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29668349/climacteric-women-at-work-what-lurks-behind-poor-occupational-quality-of-life
#15
Tatjana Gazibara, Biljana Rancic, Sanja Radovanovic, Ilma Kurtagic, Selmina Nurkovic, Nikolina Kovacevic, Jelena Dotlic
Physical and psychological changes during menopausal transition may affect various aspects of everyday functioning including women's work ability and work productivity. Presence of menopausal symptoms has been well-acknowledged to negatively affect quality of life (QOL). However, data on factors associated with occupational QOL among women at this period of life are lacking. The authors' purpose in this study was to evaluate factors affecting occupational QOL in a sample of employed mid-life women who are experiencing menopause...
April 18, 2018: Health Care for Women International
https://www.readbyqxmd.com/read/29643431/an-estradiol-independent-bdnf-npy-cascade-is-involved-in-the-antidepressant-effect-of-mechanical-acupuncture-instruments-in-ovariectomized-rats
#16
Su Yeon Seo, Ji-Young Moon, Suk-Yun Kang, O Sang Kwon, Sunoh Kwon, Se Kyun Bang, Soo Phil Kim, Kwang-Ho Choi, Yeonhee Ryu
Menopause-related depression devastates women's quality of life after middle age. Previous research has shown that estrogen hormone therapy has serious adverse effects; thus, complementary and integrative therapies have been considered clinically. The present study investigates whether stimulation of an acupoint using a mechanical acupuncture instrument (MAI) can mitigate depression-like behavior caused by estrogen deficiency in ovariectomized (OVX) rats. The animals were divided into Sham OVX, OVX, OVX + Sameumgyo (SP6) and OVX + NonAcu (non-acupuncture point) groups...
April 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29622056/psychosocial-and-health-related-risk-factors-for-depressive-symptom-trajectories-among-midlife-women-over-15-years-study-of-women-s-health-across-the-nation-swan
#17
Joyce T Bromberger, Laura L Schott, Nancy E Avis, Sybil L Crawford, Sioban D Harlow, Hadine Joffe, Howard M Kravitz, Karen A Matthews
BACKGROUND: Psychosocial and health-related risk factors for depressive symptoms are known. It is unclear if these are associated with depressive symptom patterns over time. We identified trajectories of depressive symptoms and their risk factors among midlife women followed over 15 years. METHODS: Participants were 3300 multiracial/ethnic women enrolled in a multisite longitudinal menopause and aging study, Study of Women's Health Across the Nation. Biological, psychosocial, and depressive symptom data were collected approximately annually...
April 6, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29609615/metabolic-syndrome-in-hypertensive-women-in-the-age-of-menopause-a-case-study-on-data-from-general-practice-electronic-health-records
#18
Šefket Šabanović, Majnarić Trtica Ljiljana, František Babič, Michal Vadovský, Ján Paralič, Aleksandar Včev, Andreas Holzinger
BACKGROUND: There is potential for medical research on the basis of routine data used from general practice electronic health records (GP eHRs), even in areas where there is no common GP research platform. We present a case study on menopausal women with hypertension and metabolic syndrome (MS). The aims were to explore the appropriateness of the standard definition of MS to apply to this specific, narrowly defined population group and to improve recognition of women at high CV risk. METHODS: We investigated the possible uses offered by available data from GP eHRs, completed with patients interview, in goal of the study, using a combination of methods...
April 2, 2018: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/29561915/relationship-between-symptoms-of-temporomandibular-disorders-and-estrogen-levels-in-women-with-different-menstrual-status
#19
Nedeljka Ivković, Maja Racic, Radoslavka Lecic, Djordje Bozovic, Milan Kulic
AIMS: To evaluate whether serum estrogen level is associated with chronic pain, masticatory dysfunction, and depressive symptoms and/or somatization in women with temporomandibular disorders (TMD) and different menstrual cycle status. METHODS: A total of 64 women were allocated into one of three groups: one composed of women with normal menstrual cycles (Group 1), one composed of pregnant women (Group 2), and one composed of women in surgical menopause (Group 3)...
March 21, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29545008/the-international-society-for-the-study-of-women-s-sexual-health-process-of-care-for-management-of-hypoactive-sexual-desire-disorder-in-women
#20
REVIEW
Anita H Clayton, Irwin Goldstein, Noel N Kim, Stanley E Althof, Stephanie S Faubion, Brooke M Faught, Sharon J Parish, James A Simon, Linda Vignozzi, Kristin Christiansen, Susan R Davis, Murray A Freedman, Sheryl A Kingsberg, Paraskevi-Sofia Kirana, Lisa Larkin, Marita McCabe, Richard Sadovsky
The International Society for the Study of Women's Sexual Health process of care (POC) for management of hypoactive sexual desire disorder (HSDD) algorithm was developed to provide evidence-based guidelines for diagnosis and treatment of HSDD in women by health care professionals. Affecting 10% of adult females, HSDD is associated with negative emotional and psychological states and medical conditions including depression. The algorithm was developed using a modified Delphi method to reach consensus among the 17 international panelists representing multiple disciplines...
April 2018: Mayo Clinic Proceedings
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