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https://www.readbyqxmd.com/read/29150165/effects-of-programmed-exercise-on-depressive-symptoms-in-midlife-and-older-women-a-meta-analysis-of-randomized-controlled-trials
#1
REVIEW
Faustino R Pérez-López, Samuel J Martínez-Domínguez, Héctor Lajusticia, Peter Chedraui
OBJECTIVE: To perform a systematic review and meta-analysis to clarify the effect of programmed exercise on depressive symptoms (DSs) in midlife and older women. METHODS: We carried out a structured search of PubMed-Medline, Web of Science, Scopus, Embase, Cochrane Library and Scielo, from database inception through June 29, 2017, without language restriction. The search included the following terms: "depression", "depressive symptoms", "exercise", "physical activity", "menopause", and "randomized controlled trial" (RCTs) in midlife and older women...
December 2017: Maturitas
https://www.readbyqxmd.com/read/29112595/risk-factors-associated-with-intensity-of-climacteric-symptoms-in-brazilian-middle-aged-women-a-population-based-household-survey
#2
Jeffrey Frederico Lui-Filho, Adriana Orcesi Pedro, Luiz Francisco Baccaro, Lucia Costa-Paiva
OBJECTIVE: To determine the factors associated with the intensity of climacteric somatovegetative, psychological, and urogenital symptoms among middle-aged women in the Metropolitan Region of Campinas, Brazil. METHODS: A cross-sectional population-based household survey was conducted with 749 women aged 45 to 60 years. The dependent variable was the intensity of menopausal symptoms assessed using the Menopause Rating Scale. The independent variables were sociodemographic data, health-related habits and problems, self-perception of health, and gynecological background...
November 6, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29110803/sexual-dysfunction-in-primary-care-an-exploratory-descriptive-analysis-of-medical-record-diagnoses
#3
Katie M Heiden-Rootes, Joanne Salas, Sarah Gebauer, Matthew Witthaus, Jeffrey Scherrer, Kristin McDaniel, Dasha Carver
BACKGROUND: The prevalence of sexual dysfunction (SDx) diagnoses in primary care settings is not well known, which is a concern because of the high prevalence of comorbid chronic health conditions in patients diagnosed with SDx. AIM: To explore the relation of SDx diagnosis, chronic health conditions, and prescription medications commonly associated with SDx for men and women in primary care using medical records diagnoses. METHODS: Exploratory descriptive analyses were used to interpret secondary data from a primary care patient database...
November 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29074884/evidence-for-stress-like-alterations-in-the-hpa-axis-in-women-taking-oral-contraceptives
#4
Johannes Hertel, Johanna König, Georg Homuth, Sandra Van der Auwera, Katharina Wittfeld, Maik Pietzner, Tim Kacprowski, Liliane Pfeiffer, Anja Kretschmer, Melanie Waldenberger, Gabi Kastenmüller, Anna Artati, Karsten Suhre, Jerzy Adamski, Sönke Langner, Uwe Völker, Henry Völzke, Matthias Nauck, Nele Friedrich, Hans Joergen Grabe
Using oral contraceptives has been implicated in the aetiology of stress-related disorders like depression. Here, we followed the hypothesis that oral contraceptives deregulate the HPA-axis by elevating circulating cortisol levels. We report for a sample of 233 pre-menopausal women increased circulating cortisol levels in those using oral contraceptives. For women taking oral contraceptives, we observed alterations in circulating phospholipid levels and elevated triglycerides and found evidence for increased glucocorticoid signalling as the transcript levels of the glucocorticoid-regulated genes DDIT4 and FKBP5 were increased in whole blood...
October 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29071997/-effect-of-electroacupuncture-on-hypothalamus-pituitary-ovary-hpo-axis-in-rats-with-peri-menopausal-depression
#5
Xi-Rong Jiang, Lu Ren, Chun-Ri Li
OBJECTIVE: To observe the effect of electroacupuncture (EA) on the hormones derived from the hypothalamus-pituitary-ovary (HPO) axis, so as to explore the neuroendocrine mechanism induced by EA on rats with perimenopausal depression disorder. METHODS: Sixty female sprague-dawley rats were randomly divided into blank control group, model group, sham-operation (sham) group, clomipramine group, and electroacupuncture (EA) group, with 12 rats in each group. Perimenopausal depression model was established by bilateral ovariectomy combined with chronic unpredictable stimulation...
February 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29069110/vortioxetine-for-major-depressive-disorder-vasomotor-and-cognitive-symptoms-associated-with-the-menopausal-transition
#6
Marlene P Freeman, Laura J Cheng, Danna Moustafa, Abigail Davies, Alexandra Z Sosinsky, Betty Wang, Laura F Petrillo, Charlotte Hogan, Lee S Cohen
BACKGROUND: In a preliminary trial, we assessed the efficacy of vortioxetine for major depressive disorder (MDD) during the menopausal transition. Secondary outcomes included hot flashes (HFs), anxiety, and cognitive complaints. METHODS: Perimenopausal and early postmenopausal women with MDD (N = 27) received 8 weeks of open-label, flexible-dose treatment with vortioxetine. The Montgomery-Åsberg Depression Rating Scale (MADRS) was the primary outcome measure. Secondary measures included: HF frequency, the Greene Climacteric Scale (GCS), Menopause-Specific Quality of Life Questionnaire (MEN-QOL), Beck Anxiety Inventory (BAI), Cognitive and Physical Functioning Questionnaire (CPFQ), Digit Symbol Substitution Test (DSST), and Cogstate testing...
November 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/29061416/prevalence-of-depression-among-middle-aged-women-in-the-rural-area-of-kerala
#7
Archana Ps, Soumitra Das, Sairu Philip, Rekha Rachel Philip, Jose Joseph, Varghese P Punnoose, Deepthilal Pachan Lalithambika
AIMS: The aim of this study was to determine the prevalence of Depression among women aged 40-60 years in the rural area of Kerala using Patient Health Questionnaire 9 (PHQ-9). SETTINGS AND DESIGN: Ambalappuzha is an area of rural background under the District of Alappuzha. The study was conducted by Preventive and Social Medicine department of Govt. T. D. Medical College, Kerala in collaboration with the department of Psychiatry with the help of Ambalappuzha health centre...
October 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29054014/sex-differences-in-behavioral-and-neurochemical-effects-of-gonadectomy-and-aromatase-inhibition-in-rats
#8
N Kokras, N Pastromas, D Papasava, C de Bournonville, C A Cornil, C Dalla
Aromatase inhibitors, which are widely used for the treatment of estrogen-dependent cancers, have been associated with psychiatric side effects ranging from mania to depression. In the present study, we investigated sex differences in the behavioral and neurochemical effects of aromatase inhibition on male and female, sham-operated or gonadectomized adult rats. Three weeks after surgery, rats received chronic treatment with the aromatase inhibitor letrozole or vehicle and were then subjected to the open field test, which assesses general activity...
October 10, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29040218/perimenopausal-depression-and-early-menopause-cause-or-consequence
#9
Katherine M Reding, Peter J Schmidt, David R Rubinow
No abstract text is available yet for this article.
October 16, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29031895/chronic-pelvic-pain-in-an-interdisciplinary-setting-1-year-prospective%C3%A2-cohort
#10
Catherine Allaire, Christina Williams, Sonja Bodmer-Roy, Sean Zhu, Kristina Arion, Kristin Ambacher, Jessica Wu, Ali Yosef, Fontayne Wong, Heather Noga, Susannah Britnell, Holly Yager, Mohamed A Bedaiwy, Arianne Y Albert, Sarka Lisonkova, Paul J Yong
BACKGROUND: Chronic pelvic pain affects ∼15% of women, and presents a challenging problem for gynecologists due to its complex etiology involving multiple comorbidities. Thus, an interdisciplinary approach has been proposed for chronic pelvic pain, where these multifactorial comorbidities can be addressed by different interventions at a single integrated center. Moreover, while cross-sectional studies can provide some insight into the association between these comorbidities and chronic pelvic pain severity, prospective longitudinal cohorts can identify comorbidities associated with changes in chronic pelvic pain severity over time...
October 12, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29024954/physical-activity-a-primary-health-quality-determinant-among-community-dwelling-geriatric-women-in-taiwan
#11
Ching Hwa Hsu, Heng-Hsin Tung, Daniel L Clinciu, Liang-Kung Chen, Wei-Hsian Yin, Usman Iqbal, Tsae-Jyy Wang
Objective: To investigate the associations between frailty, physical activity and depression in community-dwelling geriatric women. Design: A cross-sectional research design. Setting: Community geriatric women in Illan County, Taiwan. Study participants: Of note 216 participants, 65 years and older with full mobility, independent and able to communicate in Mandarin or Taiwanese Hokkien. Main Outcome Measures: An average weekly physical activity score International Physical Activity Questionnaire-Short Form (IPAQ-SF) and Taiwan Geriatric Depression Scale...
August 19, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28979126/depression-and-family-support-in-breast-cancer-patients
#12
Jian-An Su, Dah-Cherng Yeh, Ching-Chi Chang, Tzu-Chin Lin, Ching-Hsiang Lai, Pei-Yun Hu, Yi-Feng Ho, Vincent Chin-Hung Chen, Tsu-Nai Wang, Michael Gossop
BACKGROUND: Breast cancer is the most common cancer in women. Among the survivors, depression is one of the most common psychiatric comorbidities. This paper reports the point prevalence of major depressive disorder among breast cancer patients and the association between family support and major depressive disorder. METHODS: Clinical data were collected from a breast cancer clinic of a general hospital in central Taiwan. Participants included 300 patients who were older than 18 years and diagnosed with breast cancer...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28966324/association-between-blood-pressure-lowering-and-quality-of-life-by-treatment-of-azilsartan
#13
MULTICENTER STUDY
Nobuharu Fujiwara, Atsushi Tanaka, Atsushi Kawaguchi, Motoko Tago, Jun-Ichi Oyama, Yasufumi Uchida, Kazuo Matsunaga, Kazuo Moroe, Shigeru Toyoda, Teruo Inoue, Hideo Ikeda, Koichi Node
The authors assessed the effects of switching from a conventional angiotensin II receptor blocker (ARB) to azilsartan on blood pressure (BP) and health-related quality of life (HR-QOL) in patients with uncontrolled hypertension. Key eligibility criteria were uncontrolled hypertension treated for ≥ 1 month with an ARB, excluding azilsartan, that did not reach the target BP. We recruited 147 patients (64 males and 83 females; mean ± standard deviation age 73 ± 15 years). Azilsartan reduced both systolic and diastolic BP significantly, from 151 ± 16/82 ± 12 to 134 ± 17/73 ± 12 mm Hg, 3 months after switching...
October 21, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28934376/managing-menopausal-symptoms-and-associated-clinical-issues-in-breast-cancer-survivors
#14
REVIEW
Richard J Santen, Cynthia A Stuenkel, Susan R Davis, JoAnn V Pinkerton, Anne Gompel, Mary Ann Lumsden
Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and expert opinion from professional societies. Background: Symptoms and clinical problems associated with estrogen depletion-sleep disorders, vulvovaginal atrophy (VVA), vasomotor symptoms (VMS), mood changes, depressive symptoms, cardiovascular disease, osteopenia, and osteoporosis-confront the estimated 9...
October 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28930222/add-on-complementary-medicine-in-cancer-care-evidence-in-literature-and-experiences-of-integration
#15
REVIEW
Elio Rossi, Mariella Di Stefano, Fabio Firenzuoli, Maria Valeria Monechi, Sonia Baccetti
Background: According to the literature an increasing number of cancer patients demand for complementary therapies during their disease. Research has demonstrated that some of these therapies are effective and safe as adjunctive treatments in specific symptoms of these patients. Methods: The aims of the paper are to review the main and recent papers of international literature on the effectiveness of complementary medicine (CM) therapies on side effects of anti-cancer protocols and improvement in the quality of life of oncological patients, and to describe the integration of evidence-based acupuncture, herbal medicine and homeopathy treatments in Public Cancer Network of the region of Tuscany...
January 24, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28923310/factors-associated-with-specific-diagnostic-and-statistical-manual-of-mental-disorders-fourth-edition-sexual-dysfunctions-in-breast-cancer-survivors-a-study-of-patients-and-their-partners
#16
Susanna B Hummel, Daniela E E Hahn, Jacques J D M van Lankveld, Hester S A Oldenburg, Eva Broomans, Neil K Aaronson
BACKGROUND: Many women develop sexual problems after breast cancer (BC) treatment. Little is known about BC survivors with a Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) sexual dysfunction and their partners, and the factors associated with their sexual functioning. AIM: To evaluate (i) patient-related and clinical factors associated with (a) specific DSM-IV sexual dysfunctions and (b) level of sexual functioning and sexual distress as reported by BC survivors and (ii) the association between the sexual functioning of BC survivors and that of their partners...
October 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28899509/a-standardized-humulus-lupulus-l-ethanol-extract-partially-prevents-ovariectomy-induced-bone-loss-in-the-rat-without-induction-of-adverse-effects-in-the-uterus
#17
Annekathrin M Keiler, Janina Helle, Manuela I Bader, Tino Ehrhardt, Kristin Nestler, Georg Kretzschmar, Ricardo Bernhardt, Günter Vollmer, Dejan Nikolić, Judy L Bolton, Guido F Pauli, Shao-Nong Chen, Birgit M Dietz, Richard B van Breemen, Oliver Zierau
BACKGROUND: Hops (Humulus lupulus (L.)) dietary supplements are of interest as herbal remedies to alleviate menopausal symptoms, such as hot flushes, depression and anxiety. So far, the evidence regarding estrogenic and related properties of hops preparations has been considered insufficient for a market authorization for menopausal indications. PURPOSE: The study aims to investigate a chemically standardized hops extract regarding its safety in the uterus, as wells as its efficacy to prevent bone loss in the ovariectomized rat model...
October 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28891367/effect-of-foeniculum-vulgare-fennel-on-symptoms-of-depression-and-anxiety-in-postmenopausal-women-a-double-blind-randomised-controlled-trial
#18
Masumeh Ghazanfarpour, Fatemeh Mohammadzadeh, Paymaneh Shokrollahi, Talat Khadivzadeh, Mona Najaf Najafi, Hamidreza Hajirezaee, Maliheh Afiat
The aim of this study was to evaluate the effect of Foeniculum vulgare (fennel) on anxiety and depression symptoms in postmenopausal women. This study was a double-blind, randomised, placebo-controlled trial, in which 60 eligible postmenopausal women were selected and then randomly assigned to fennel and placebo groups. Then, symptoms of anxiety and depression were measured using Hospital Anxiety and Depression Scale (HADS) and Zung's Self Rating Depression Scale (SDS). Following the intervention, the score of HADS (depression and anxiety subgroups) and SDS did not show any significant decrease in the sample under study...
September 11, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28857628/correlation-between-allopregnanolone-levels-and-depressive-symptoms-during-late-menopausal-transition-and-early-postmenopause
#19
Radoslaw Slopien, Nicola Pluchino, Alina Warenik-Szymankiewicz, Stefan Sajdak, Michele Luisi, Panagiotis Drakopoulos, Andrea R Genazzani
OBJECTIVES: This observational, cross-sectional study included 140 women with climacteric symptoms. The aim of the study was to evaluate the correlation between the presence and severity of depressive symptoms and allopregnanolone levels in women during late menopausal transition and early postmenopause. METHODS: The study group was divided into two groups: 45 women in late menopausal transition and 95 early postmenopausal women. We evaluated Kupperman index, Hamilton scale and serum follicle-stimulating hormone, luteinizing hormone, 17β-estradiol, prolactin, total testosterone, dehydroepiandrosterone sulfate and allopregnanolone levels...
August 31, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28854893/self-reported-sexual-health-breast-cancer-survivors-compared-to-women-from-the-general-population-an-observational-study
#20
Anne Oberguggenberger, Caroline Martini, Nathalie Huber, Lesley Fallowfield, Michael Hubalek, Martin Daniaux, Barbara Sperner-Unterweger, Bernhard Holzner, Monika Sztankay, Eva Gamper, Verena Meraner
BACKGROUND: Cancer survivorship is of increasing importance in post-treatment care. Sexual health (SH) and femininity can be crucial issues for women surviving cancer. We aimed to determine a more complete understanding of the contribution that a breast cancer (BC) diagnosis and its treatment exert on patients' follow-up SH. For this purpose, self-reported levels and predictors of SH in breast cancer survivors (BCS) were compared with those of women with no previous or current BC (WNBC)...
August 30, 2017: BMC Cancer
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