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Cardiac resynchronization therapy or CRT

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https://www.readbyqxmd.com/read/29667745/cardiac-resynchronization-therapy-in-clinical-practice-some-interesting-news-but-methodological-advances-are-needed
#1
EDITORIAL
Aldo P Maggioni, Luigi Tavazzi
No abstract text is available yet for this article.
April 18, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29667071/optimizing-cardiac-resynchronization-therapy-an-update-on-new-insights-and-advancements
#2
REVIEW
Adam Grimaldi, Eiran Z Gorodeski, John Rickard
PURPOSE OF REVIEW: This review focuses on the current advancements in optimizing patient response to cardiac resynchronization therapy (CRT). RECENT FINDINGS: It has been well known that not every patient will derive benefit from CRT, and of those that do, there are varying levels of response. Optimizing CRT begins well before device implant and involves appropriate patient selection and an understanding of the underlying substrate. After implant, there are different CRT device programming options that can be enabled to help overcome barriers as to why a patient may not respond...
April 17, 2018: Current Heart Failure Reports
https://www.readbyqxmd.com/read/29665405/adherence-to-2016-european-society-of-cardiology-guidelines-predicts-outcome-in-a-large-real-world-population-of-heart-failure-patients-requiring-cardiac-resynchronization-therapy-adherence-to-guidelines-predicts-crt-outcome
#3
Giuseppe Stabile, Patrizia Pepi, Pietro Palmisano, Antonio D'Onofrio, Antonio De Simone, Salvatore Ivan Caico, Domenico Pecora, Antonio Rapacciuolo, Giuseppe Arena, Massimiliano Marini, Paolo Pieragnoli, Sandra Badolati, Gianluca Savarese, Gianpiero Maglia, Assunta Iuliano, Giovanni Luca Botto, Maurizio Malacrida, Emanuele Bertaglia
BACKGROUND: Professional guidelines are based on the best available evidence. However, patients treated in clinical practice may differ from those included in reference trials. OBJECTIVE: The aim of this study was to evaluate the effects of cardiac resynchronization therapy (CRT) in a large population of patients implanted with a CRT device, stratified in accordance with the 2016 European heart failure (HF) guidelines. METHODS: We collected data on 930 consecutive patients from the CRT-MORE registry...
April 14, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29657598/late-ratchet-syndrome-involving-isolated-left-ventricular-lead-dislodgement-post-cardiac-resynchronization-therapy-defibrillator-generator-change
#4
Vern Hsen Tan, Kelvin Wong
Lead dislodgement following cardiac implantable electronic device (CIED) generator change is rare. We report a case including the postulate mechanism of an isolated left ventricular lead dislodgement 3 months after cardiac resynchronization therapy defibrillator pulse generator change.
April 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29657594/clinical-and-echocardiographic-response-of-apical-vs-nonapical-right-ventricular-lead-position-in-crt-a-meta-analysis
#5
Sharan Prakash Sharma, Khagendra Dahal, Paari Dominic, Rajbir S Sangha
Background: Traditionally the right ventricular (RV) pacing lead is placed in the RV apex in cardiac resynchronization therapy (CRT). It is not clear whether nonapical placement of the RV lead is associated with a better response to CRT. We aimed to perform a meta-analysis of all randomized controlled trials (RCTs) that compared apical and nonapical RV lead placement in CRT. Methods: We searched PubMed, EMBASE, Cochrane, Scopus, and relevant references for studies and performed meta-analysis using random effects model...
April 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29657589/prognostic-significance-of-nonsustained-ventricular-tachycardia-in-patients-receiving-cardiac-resynchronization-therapy-for-primary-prevention-analysis-of-the-japan-cardiac-device-treatment-registry-database
#6
Hisashi Yokoshiki, Akihiko Shimizu, Takeshi Mitsuhashi, Hiroshi Furushima, Yukio Sekiguchi, Tetsuyuki Manaka, Nobuhiro Nishii, Takeshi Ueyama, Norishige Morita, Hideo Okamura, Takashi Nitta, Kenzo Hirao, Ken Okumura
Background: Whether nonsustained ventricular tachycardia (NSVT) is a marker of increased risk of sustained ventricular tachyarrhythmias (VTAs) remains to be established in patients receiving cardiac resynchronization therapy with a defibrillator (CRT-D) for primary prevention. Methods: Among the follow-up data of the Japan cardiac device treatment registry (JCDTR) with an implantation date between January 2011 and August 2015, information regarding a history of NSVT before the CRT-D implantation for primary prevention had been registered in 269 patients...
April 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29657037/cardiac-resynchronization-therapy-consensus-guidelines-evolution-or-revolution
#7
EDITORIAL
Christopher A Rinaldi
No abstract text is available yet for this article.
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29657035/cardiac-resynchronization-therapy-how-did-consensus-guidelines-from-europe-and-the-united-states-evolve-in-the-last-15-years
#8
Giuseppe Boriani, Matteo Ziacchi, Martina Nesti, Antonella Battista, Filippo Placentino, Vincenzo Livio Malavasi, Igor Diemberger, Luigi Padeletti
Cardiac resynchronization therapy (CRT) was proposed around 20 years ago, and its clinical use rapidly moved from pioneering experiences to randomized controlled trials (RCT). Since 2002 recommendations for CRT have been included in international consensus guidelines that even in an early phase recommended CRT as an effective treatment for improving symptoms, reducing hospitalizations and mortality in well-selected patients with wide QRS, left ventricular dysfunction and moderate to severe heart failure (NYHA classes III-IV), on optimal medical therapy...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29652994/-association-of-osmr-gene-polymorphisms-with-dilated-cardiomyopathy-in-a-han-chinese-population
#9
Xiaohui Dai, Ying Peng, Bin Zhou, Chunmei Li, Huizi Song, Qingyu Dou, Xiaochuan Xie, Li Rao
OBJECTIVE: To assess the association of polymorphisms of oncostatin M receptor (OSMR) gene with dilated cardiomyopathy (DCM) in a Han Chinese population. METHODS: For 351 DCM patients and 418 healthy controls, two single nucleotide polymorphisms (SNPs) of the OSMR gene, namely rs2292016 (promoter, -100G/T) and rs2278329 (missense, Asp553Asn), were genotyped with a TaqMan SNP genotyping assay. Two hundred of the patients were also followed up for (49.85 ± 22.52) months...
April 10, 2018: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/29651826/new-percutaneous-interventions-in-heart-failure
#10
Elisabetta Moscarella, Salvatore Brugaletta, Manel Sabaté
Chronic heart failure (HF) is one of the main causes of mortality and morbidity worldwide and represents a growing challenge in interventional cardiology. Its prevalence is recently increasing due to the improvements in cardiac care with subsequent significant reduction in the HF acute mortality. HF may occur with either a reduced left ventricular ejection fraction (LVEF) (LVEF<40%, HFrEF) or a preserved EF (typically LVEF≥50%, HFpEF) indicative of diastolic dysfunction. Despite recent advances in drug therapies as well as in nonpharmacological strategies, including defibrillators, cardiac resynchronization therapy, LV assist devices (LVAD), mortality in HF remains high...
April 12, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29649579/prognostic-value-of-nutrition-status-in-the-response-of-cardiac-resynchronization-therapy
#11
Belén Alvarez-Alvarez, Javier García-Seara, Moisés Rodríguez-Mañero, Diego Iglesias-Alvarez, Jose L Martínez-Sande, Rosa M Agra-Bermejo, Xesús A Fernández López, Laila González-Melchor, Francisco Gude Sampedro, Carla Díaz-Louzao, José R González-Juanatey
BACKGROUND: Cardiac resynchronization therapy (CRT) is indicated in symptomatic heart failure (HF) patients after achieving optimal medical therapy. However, there are still a large percentage of patients who do not respond to CRT. Malnutrition is a frequent comorbidity in patients with HF, and it is associated with a poorer prognosis. Here, we evaluate the nutritional status of patients assessed by Controlling Nutritional Status (CONUT) score and its association with structural remodeling and cardiovascular events...
April 9, 2018: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29628471/a-case-of-a-cardiac-resynchronization-therapy-defibrillator-exhibiting-a-lower-and-alternately-variable-basic-rate
#12
Keigo Iwazaki, Toshiya Kojima, Takahide Murasawa, Jun Yokota, Hikaru Tanimoto, Jun Matsuda, Nobuaki Fukuma, Takumi Matsubara, Yu Shimizu, Gaku Oguri, Eriko Hasumi, Hitoshi Kubo, Kyungho Chang, Katsuhito Fujiu, Issei Komuro
A cardiac resynchronization therapy defibrillator (CRT-D) (Medtronic Inc. Protecta XT) was implanted in a 67-year-old man who had cardiac sarcoidosis with extremely low cardiac function. He had ventricular tachycardia which was controlled by catheter ablation, medication and pacing. The programmed mode was DDI, lower rate was 90 beats/minute, paced AV delay was 150 ms, and the noncompetitive atrial pacing (NCAP) function was programmed as 300 ms.After his admission for pneumonia and heart failure, we changed his DDI mode to a DDD mode because he had atrial tachycardia, which led to inadequate bi-ventricular pacing...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29628460/effect-of-qrs-morphology-and-duration-on-clinical-outcomes-after-cardiac-resynchronization-therapy-analysis-of-japanese-multicenter-registry
#13
Takafumi Oka, Koichi Inoue, Koji Tanaka, Yuko Hirao, Takaaki Isshiki, Takeshi Kimura, Masakiyo Nobuyoshi, Satoshi Shizuta, Takeshi Arita, Satoki Fujii, Katsuomi Iwakura, Kenshi Fujii, Kenji Ando
BACKGROUND: QRS duration (QRSd) and morphology are established response predictors of cardiac resynchronization therapy (CRT). However, evidence in Japanese populations is lacking.Methods and Results:We retrospectively analyzed the Japanese multicenter CRT database. We divided patients according to their intrinsic QRSd and morphology, and assessed echocardiographic responses and clinical outcomes. The primary endpoint was a composite of all-cause death or hospitalization because of heart failure...
April 7, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29627955/t-wave-positivity-in-lead-avr-is-associated-with-mortality-in-patients-with-cardiac-resynchronization-therapy
#14
Yahya Kemal İçen, Yurdaer Dönmez, Hasan Koca, Mehmet Uğurlu, Mevlüt Koç
PURPOSE: Positive T wave polarity in lead aVR (TPaVR) is associated with a poor prognostic indicator in patients with heart failure reduce ejection fraction (HFrEF). Our aim was to investigate the relationship between positive TPaVR and mortality in patients with cardiac resynchronization therapy defibrillator (CRT-D). METHODS: We included retrospectively 224 HFrEF patients with CRT-D in sinus rhythm. Laboratory, electrocardiographic (ECG), and echocardiographic data were recorded...
April 8, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29627954/hemodynamic-comparison-of-different-multisites-and-multipoint-pacing-strategies-in-cardiac-resynchronization-therapies
#15
Francesco Zanon, Lina Marcantoni, Enrico Baracca, Gianni Pastore, Giuseppina Giau, Gianluca Rigatelli, Daniela Lanza, Claudio Picariello, Silvio Aggio, Sara Giatti, Marco Zuin, Loris Roncon, Domenico Pacetta, Franco Noventa, Frits W Prinzen
PURPOSE: In order to increase the responder rate to CRT, stimulation of the left ventricular (LV) from multiple sites has been suggested as a promising alternative to standard biventricular pacing (BIV). The aim of the study was to compare, in a group of candidates for CRT, the effects of different pacing configurations-BIV, triple ventricular (TRIV) by means of two LV leads, multipoint (MPP), and multipoint plus a second LV lead (MPP + TRIV) pacing-on both hemodynamics and QRS duration...
April 7, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29625702/comparison-of-long-term-survival-benefits-with-cardiac-resynchronization-therapy-in-patients-with-mild-heart-failure-with-versus-without-diabetes-mellitus-from-the-multicenter-automatic-defibrillator-implantation-trial-with-cardiac-resynchronization-therapy
#16
Valentina Kutyifa, Syed Yaseen Naqvi, Mary Brown, Scott McNitt, Ilan Goldenberg, Helmut Klein, Arthur J Moss
We have previously shown a reduction in HF events with cardiac resynchronization therapy with defibrillator (CRT-D) in patients with mild heart failure (HF) and diabetes mellitus (DM). It remains unknown whether HF remission in DM patients with CRT-D translates into reduced mortality. The effects of CRT-D versus an implantable cardioverter-defibrillator (ICD) alone to reduce long-term mortality were assessed in patients with left bundle branch block with DM (n = 386) and without DM (n = 982), enrolled in the Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy (MADIT-CRT)...
March 14, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29624601/sleep-apnea-detection-by-a-cardiac-resynchronization-device-integrated-thoracic-impedance-sensor-a-validation-study-against-the-gold-standard-polysomnography
#17
Fabian Barbieri, Wolfgang Dichtl, Anna Heidbreder, Elisabeth Brandauer, Ambra Stefani, Agne Adukauskaite, Thomas Senoner, Wilfried Schgör, Florian Hintringer, Birgit Högl
BACKGROUND: Sleep disordered breathing is a common but often undiagnosed comorbidity in heart failure patients. Cardiac implantable electronic devices used for cardiac resynchronization therapy (CRT) may detect sleep apnea by use of a transthoracic impedance sensor. Validation of the AP scan® algorithm (Boston Scientific®) was performed by using the diagnostic gold standard polysomnography (PSG). METHODS: Forty-one patients with impaired left ventricular ejection fraction, frequent right ventricular pacing due to atrioventricular block and heart failure symptoms despite optimal medical therapy underwent upgrading to biventricular pacing...
2018: PloS One
https://www.readbyqxmd.com/read/29622980/successful-pregnancies-after-transvenous-cardiac-resynchronization-therapy-in-a-woman-with-congenitally-corrected-transposition-of-the-great-arteries
#18
Sana Ouali, Slim Kacem, Rim Gribaa, Elyes Neffeti, Fahmi Remedi, Essia Boughzela
Congenitally corrected transposition of the great arteries is a rare heart defect that can be associated with systemic ventricular dysfunction and conduction disturbances. The use of cardiac resynchronization therapy in patients with congenital heart disease is not fully established, and achievement of successful pregnancies after implantation of transvenous, biventricular system has never been described, and which resulted in a significant clinical improvement. We describe a 33-year-old female with congenitally corrected transposition of the great arteries, who achieved six pregnancies and successful vaginal deliveries...
September 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29622458/usefulness-of-a-clinical-risk-score-to-predict-the-response-to-cardiac-resynchronization-therapy
#19
Rui Providencia, Eloi Marijon, Sergio Barra, Christian Reitan, Alexander Breitenstein, Pascal Defaye, Nikolaos Papageorgiou, Rudolph Duehmke, Stephan Winnik, Richard Ang, Didier Klug, Daniel Gras, Tardu Oezkartal, Oliver R Segal, Jean-Claude Deharo, Christophe Leclercq, Pier D Lambiase, Laurent Fauchier, Pierre Bordachar, Jan Steffel, Nicolas Sadoul, Olivier Piot, Rasmus Borgquist, Sharad Agarwal, Anthony Chow, Serge Boveda
BACKGROUND: Almost 1/3 of heart failure patients fail to respond to cardiac resynchronization therapy (CRT). A simple clinical score to predict who these patients are at the moment of referral or at time of implant may be of importance for early optimization of their management. METHODS: Observational study. A risk score was derived from factors associated to CRT response. The derivation cohort was composed of 1301 patients implanted with a CRT defibrillator in a multi-center French cohort-study...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29622417/can-we-screen-response-to-cardiac-resynchronization-therapy-by-a-simple-score
#20
EDITORIAL
Tsuneaki Sadanaga
No abstract text is available yet for this article.
June 1, 2018: International Journal of Cardiology
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