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Cardiac resynchronization therapy or CRT

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https://www.readbyqxmd.com/read/29452309/echocardiography-for-the-management-of-patients-with-biventricular-pacing-possible-roles-in-cardiac-resynchronization-therapy-implementation
#1
REVIEW
Emmanouil Poulidakis, Constantina Aggeli, Konstantinos Kappos, Antonis S Manolis, Skevos Sideris, Konstantinos Gatzoulis, Evangelos Oikonomou, Dimitrios Tousoulis
Cardiac Resynchronization Therapy (CRT) is an established therapeutic option for the subset of patients with heart failure (HF), reduced ejection fraction (EF) and dyssynchrony evidenced by electrocardiography. Benefit from CRT has been proven in many clinical trials, yet a sizeable proportion of these patients with wide QRS do not respond to this intervention, despite the updated practice guidelines. Several echocardiographic indices, targeting mechanical rather than electrical dyssynchrony, have been suggested to address this issue, but research so far has not succeeded in providing a single and simple measurement with adequate sensitivity and specificity for identification of responders...
February 13, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29442199/multisite-cardiac-resynchronization-therapy-for-traditional-and-non-traditional-indications
#2
Avishag Laish-Farkash, Sharon Bruoha, Vladimir Khalameizer, Chaim Yosefy, Yoav Michowitz, Mahmoud Suleiman, Amos Katz
PURPOSE: Multisite cardiac resynchronization therapy (MSCRT) with dual-vein left ventricular (LV) pacing has theoretical advantages over conventional CRT in faster and more physiological LV activation. We aimed to define indications, feasibility, safety, acute, and long-term results of MSCRT. METHODS: All patients implanted with MSCRT during 2008-2014 in a single center were reviewed and analyzed. RESULTS: Thirty-nine patients (90% CRT-defibrillators, 64 ± 9 years, 85% male, 74% ischemic etiology) were included...
February 13, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29439300/angiovac-system-used-as-an-adjunct-treatment-for-intra-cardiac-lead-and-valvular-vegetations
#3
Vishesh Kumar, Shahbaz A Malik, Maryam Sheikh, Adam Stys
Infections are known complications of cardiovascular implantable electronic devices (CIEDs). We describe a case of a 62-year-old male who presented with pulseless electrical activity (PEA) cardiac arrest and respiratory failure. He had a history of cardiac resynchronization device and defibrillator (CRT-D) implantation for nonischemic cardiomyopathy. After resuscitation, he was found to have methicillin sensitive Staphylococcus aureus (MSSA) bacteremia on blood culture and large vegetations on the CRT-D lead and tricuspid valve found on echocardiography...
January 2018: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/29435997/coronary-venous-angioplasty-to-facilitate-trans-venous-left-ventricular-lead-placement-a-single-center-13-year-experience
#4
Aaron B Hesselson, Sandeep Duggal, Michael Rukavina, Peter L Gallagher, Gery F Tomassoni
BACKGROUND: Barriers to successful left ventricular lead placement within the coronary venous anatomy may include focal stenoses, thromboses, phrenic nerve stimulation, vessel tortuosity, small vessel caliber, non-excitable tissue and valve presence. A large series describing the utilization of coronary venous angioplasty (CVAP) for relief of these issues is absent in the literature. OBJECTIVE: We report our experience for all patients treated with CVAP in a single-center 13-year experience...
February 12, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29435789/chronic-right-ventricular-pacing-in-the-heart-failure-population
#5
REVIEW
Justin Gould, Benjamin Sieniewicz, Bradley Porter, Baldeep Sidhu, Christopher A Rinaldi
PURPOSE OF REVIEW: We review the trials that have demonstrated potentially harmful effects from right ventricular (RV) apical pacing as well as reviewing the evidence of alternative RV pacing sites and cardiac resynchronization therapy (CRT) for patients who have heart failure and atrioventricular (AV) block. RECENT FINDINGS: The role of CRT in patients with AV block and impaired left ventricular function remains an important consideration. The BLOCK HF trial demonstrated better outcomes with CRT pacing over RV pacing in patients with left ventricular systolic dysfunction (LVSD) and AV block who were expected to have a high RV pacing burden, but failed to demonstrate a mortality benefit...
February 12, 2018: Current Heart Failure Reports
https://www.readbyqxmd.com/read/29432133/programming-cardiac-resynchronization-therapy-for-electrical-synchrony-reaching-beyond-left-bundle-branch-block-and-left-ventricular-activation-delay
#6
Niraj Varma, David O'Donnell, Mohammed Bassiouny, Philippe Ritter, Carlo Pappone, Jan Mangual, Daniel Cantillon, Nima Badie, Bernard Thibault, Brian Wisnoskey
BACKGROUND: QRS narrowing following cardiac resynchronization therapy with biventricular (BiV) or left ventricular (LV) pacing is likely affected by patient-specific conduction characteristics (PR, qLV, LV-paced propagation interval), making a universal programming strategy likely ineffective. We tested these factors using a novel, device-based algorithm (SyncAV) that automatically adjusts paced atrioventricular delay (default or programmable offset) according to intrinsic atrioventricular conduction...
February 6, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29431254/guideline-recommendations-for-cardiac-resynchronization-therapy-evolve-but-does-clinical-practice-match-the-pace
#7
EDITORIAL
Camilla Normand, Kenneth Dickstein
No abstract text is available yet for this article.
February 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29428140/right-ventricular-pacing-and-cardiac-resynchronization-devices
#8
REVIEW
Tharian S Cherian, Gaurav A Upadhyay
Long-term right ventricular pacing is associated with electrical and mechanical dyssynchrony and ultimately development of pacing-induced cardiomyopathy (PICM) in a subset of patients. Patients with a high degree of pacing burden and reduced left ventricular (LV) function prior to pacemaker implantation are at the greatest risk for developing PICM. Cardiac resynchronization therapy (CRT) has an established role in the treatment of patients with LV systolic heart failure and intraventricular delay and has been used to successfully treat PICM...
March 2018: Cardiac Electrophysiology Clinics
https://www.readbyqxmd.com/read/29428139/leadless-pacemakers-state-of-the-art-and-future-perspectives
#9
REVIEW
Domenico G Della Rocca, Carola Gianni, Luigi Di Biase, Andrea Natale, Amin Al-Ahmad
Leadless pacemaker therapy is a new technology that aims at avoiding lead- and pocket-related complications of conventional transvenous and epicardial pacing. To date, 2 self-contained leadless pacemakers for right ventricular pacing have been clinically available: the Nanostim Leadless Pacemaker System and the Micra Transcatheter Pacing System. Additionally, a new multicomponent leadless pacemaker for endocardial left ventricular pacing has been proposed as an alternative choice for cardiac resynchronization therapy...
March 2018: Cardiac Electrophysiology Clinics
https://www.readbyqxmd.com/read/29425569/significant-impact-of-electrical-storm-on-mortality-in-patients-with-structural-heart-disease-and-an-implantable-cardiac-defibrillator
#10
Takashi Noda, Takashi Kurita, Takashi Nitta, Yasutaka Chiba, Hiroshi Furushima, Naoki Matsumoto, Takeshi Toyoshima, Akihiko Shimizu, Hideo Mitamura, Ken Okumura, Tohru Ohe, Yoshifusa Aizawa
BACKGROUND: Electrical storm (E-Storm), defined as multiple episodes of ventricular arrhythmias within a short period of time, is an important clinical problem in patients with an implantable cardiac defibrillator (ICD) including cardiac resynchronization therapy devices capable of defibrillation. The detailed clinical aspects of E-Storm in large populations especially for non-ischemic dilated cardiomyopathy (DCM), however, remain unclear. OBJECTIVE: This study was performed to elucidate the detailed clinical aspects of E-Storm, such as its predictors and prevalence among patients with structural heart disease including DCM...
March 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29425552/sex-related-differences-in-chronic-heart-failure
#11
Alberto Aimo, Giuseppe Vergaro, Andrea Barison, Silvia Maffei, Chiara Borrelli, Doralisa Morrone, Matteo Cameli, Alberto Palazzuoli, Giuseppe Ambrosio, Stefano Coiro, Ketty Savino, Elisabetta Cerbai, Rossella Marcucci, Roberto Pedrinelli, Luigi Padeletti, Claudio Passino, Michele Emdin
The prevalence of chronic heart failure (CHF) is steadily increasing. Both sexes are affected, with significant differences in etiology, epidemiology and clinical presentation, prognosis, comorbidities, and response to treatment. Women tend to develop CHF at a more advanced age, present more often with HF with preserved ejection fraction, are more symptomatic, and have a worse quality of life than men, but also a better prognosis. In women, CHF has more frequently a non-ischemic etiology, and arterial hypertension and diabetes mellitus are leading comorbidities...
March 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29424196/exercise-based-cardiac-rehabilitation-in-cardiac-resynchronization-therapy-recipients-a-primer-for-practicing-clinicians
#12
Marco Ambrosetti, Simona Sarzi Braga, Franco Giada, Roberto F E Pedretti
Cardiac resynchronization therapy (CRT) is a therapeutic option of increasing importance for chronic heart failure (CHF) and criteria for implantation now concern a large amount of patient populations. As a consequence, subjects with ongoing CRT (or immediately after CRT implantation) are more often referred to Cardiac Rehabilitation (CR) programmes, and it has been recently estimated that about one third of CHF patients attending CR in Italy currently have this kind of device. The presence of CRT represents a modulating factor for exercise prescription and monitoring, since CRT patients may be considered per se as a target group for CR...
November 30, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/29411719/gender-differences-and-demographics-and-type-of-cardiac-device-over-a-10-year-period
#13
M Aktoz, M F Uçar, M A Yılmaztepe, G Taylan, S Altay
AIMS: This study aims to review the influence of gender-specific differences and patient demographics on cardiac device and pacing mode selection over a 10-year period. METHODS: We retrospectively reviewed patients who underwent first implantation of the cardiac device between January 1, 2006 and June 31, 2016. RESULTS: During the study period, 704 patients underwent first cardiac device implantation. Number of patients undergoing pacemaker was 452 and number of patients undergoing implantable cardioverter defibrillator/cardiac resynchronization therapy and defibrillator (ICD/CRT-D) was 252...
January 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29409794/management-of-complications-caused-by-a-massive-left-ventricle-tumor-in-a-neonate
#14
Mouhammad Yabrodi, Christopher W Mastropietro, Robert K Darragh, John J Parent, Mark D Ayres, Adam C Kean, Mark Turrentine
We report a case of a neonate born with a giant fibroma occupying the entirety of her left ventricle. Due to the extensive resection, her postoperative course was complicated by severely diminished left ventricular function and complete heart block necessitating extracorporeal support. Ultimately, cardiac resynchronization therapy was employed, after which the infant's ventricular function gradually improved and she was successfully discharged to home.
February 1, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29405324/combination-of-the-best-pacing-configuration-and-atrioventricular-and-interventricular-delays-optimization-in-cardiac-resynchronization-therapy
#15
Pierre Socie, Fabien Squara, Marc Semichon, Olivier Thomas, Alain Khemache, Philippe Riccini, Pierre Squara, Vincent Algalarrondo, Ghassan Moubarak
BACKGROUND: Cardiac resynchronization therapy optimization can be pursued by left ventricular pacing vector selection, atrioventricular (AV) and interventricular (VV) delays optimization. The combination of these methods and its comparison with multipoint pacing (MPP) is scarcely studied. METHODS: Using non-invasive cardiac output (CO) measurement, the best of five left ventricular pacing vectors was determined, then AV and VV delays optimization was applied on top of the best vector...
February 6, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29402420/effect-of-optimization-of-medical-treatment-on-long-term-survival-of-patients-with-heart-failure-after-implantable-cardioverter-defibrillator-and-cardiac-resynchronization-device-implantation-from-the-french-national-egb-database
#16
Grégoire Massoullié, Chenaf Chouki, Aurélien Mulliez, Patrick Rossignol, Sylvain Ploux, Bruno Pereira, Adrien Reuillard, Fréderic Jean, Marius Andronache, Alain Eschalier, Pascal Motreff, Guillaume Clerfond, Pierre Bordachar, Nicolas Authier, Romain Eschalier
Prognosis of heart failure with reduced ejection fraction (HFrEF) is improved by drug optimization according to guidelines; however, little is known regarding such optimization in HFrEF patients with an implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy (CRT). This study aimed to describe implementation of this optimized strategy and its impact in patients implanted with an ICD/CRT. Using a 1/97th representative sample of the French national health-care insurance system claims database, a retrospective cohort study was conducted including HFrEF patients implanted with ICD or CRT between January 2009 and December 2014...
January 3, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29399763/significant-mitral-regurgitation-predicts-the-long-term-prognosis-in-patients-receiving-cardiac-resynchronization-therapy
#17
Han Jin, Shengwen Yang, Wei Hua, Min Gu, Hongxia Niu, Ligang Ding, Jing Wang, Cong Xue, Shu Zhang
BACKGROUND: Cardiac resynchronization therapy (CRT) has been shown to reduce Functional mitral regurgitation (FMR), although the relationship between significant mitral regurgitation (SMR) and the clinical prognosis of CRT remains uncertain. AIM: To investigate the association of baseline of SMR with long-term outcomes in patients undergoing CRT. METHODS: A total of 296 consecutive patients undergoing CRT were enrolled. SMR was quantified by color Doppler in all the patients at baseline and defined as grading scale ≥ 3...
February 5, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29391388/a-patient-with-left-bundle-branch-block-and-persistent-atrial-fibrillation-treated-with-cardiac-catheter-ablation-and-pharmacologic-cardiac-resynchronization-therapy-without-the-use-of-an-implantable-cardiac-device
#18
Hideyuki Hasebe
BACKGROUND Left bundle branch block (LBBB) is associated with atrial fibrillation (AF) and systolic heart failure, which can be treated with cardiac resynchronization therapy (CRT) that includes an implantable cardiac device (ICD). However, in some patients, LBBB may vary with heart rate, and during episodes of AF in LBBB, aberrant ventricular conduction, or wide QRS complex tachycardia (Ashman beats) can occur. This report is a case of LBBB treated with pharmacologic CRT, without the use of an ICD. CASE REPORT A 68-year-old man presented with persistent AF and systolic heart failure...
February 2, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29388068/characterizing-left-ventricular-mechanical-and-electrical-activation-in-patients-with-normal-and-impaired-systolic-function-using-a-non-fluoroscopic-cardiovascular-navigation-system
#19
Christopher Piorkowski, Arash Arya, Craig D Markovitz, Hedi Razavi, Chunlan Jiang, Stuart Rosenberg, Ole-A Breithardt, Sascha Rolf, Silke John, Jedrzej Kosiuk, Yan Huo, Michael Döring, Sergio Richter, Kyungmoo Ryu, Thomas Gaspar, Frits W Prinzen, Gerhard Hindricks, Philipp Sommer
PURPOSE: Cardiac disease frequently has a degenerative effect on cardiac pump function and regional myocardial contraction. Therefore, an accurate assessment of regional wall motion is a measure of the extent and severity of the disease. We sought to further validate an intra-operative, sensor-based technology for measuring wall motion and strain by characterizing left ventricular (LV) mechanical and electrical activation patterns in patients with normal (NSF) and impaired systolic function (ISF)...
January 31, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29387972/effect-of-cardiac-resynchronization-therapy-on-mitral-valve-geometry-a-novel-aspect-as-reversed-mitral-remodeling
#20
Oguz Karaca, Beytullah Cakal, Mehmet Onur Omaygenc, Haci Murat Gunes, Filiz Kizilirmak, Sinem Deniz Cakal, Deniz Dilan Naki, Irfan Barutcu, Bilal Boztosun, Fethi Kilicaslan
Amelioration of the valvular geometry is a possible mechanism for mitral regurgitation (MR) improvement in patients receiving cardiac resynchronization therapy (CRT). We aimed to establish the precise definition, incidence, and predictors of reversed mitral remodeling (RMR), as well as the association with MR improvement and short-term CRT outcome. Ninety-five CRT recipients were retrospectively evaluated for the end-point of "MR response" defined as the absolute reduction in regurgitant volume (RegV) at 6 months...
January 31, 2018: International Journal of Cardiovascular Imaging
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