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Cardiac resynchronization therapy or CRT

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https://www.readbyqxmd.com/read/29054593/association-between-the-baseline-peripheral-blood-monocyte-counts-the-size-of-spleen-and-the-response-to-cardiac-resynchronization-therapy
#1
Mami Fujinami, Hidekazu Kondo, Kunio Yufu, Tetsuji Shinohara, Yumi Ishii, Yasushi Teshima, Mikiko Nakagawa, Naohiko Takahashi
BACKGROUND: Spleen reserves monocytes, which deploy to inflammatory sites. Monocytosis is known to be observed in chronic low-grade inflammatory state, including chronic heart failure (CHF). CHF also induces splenomegaly. We tested the hypotheses that the number of peripheral blood monocytes and size of spleen at baseline could be related to the response to cardiac resynchronization therapy (CRT). METHODS: From 2010, a total of 49 consecutive patients implanted with CRT device were evaluated at baseline and 6-8 months later...
October 17, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/29054206/corrigendum-to-cardiac-resynchronization-therapy-in-patients-with-mild-heart-failure-is-a-reversal-therapy-indian-heart-j-69-1-2017-112-118
#2
Sadeq Ali-Hasan-Al-Saegh, Seyed Jalil Mirhosseini, Ali Akbar Karimi-Bondarabadi, Azadeh Shahidzadeh, Parisa Mahdavi, Mahbube Tahernejad, Safieyehsadat Heydari, Alexander Weymann, Mohamed Zeriouh, Anton Sabashnikov, Aron-Frederik Popov
No abstract text is available yet for this article.
September 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29052249/image-noise-reduction-technology-allows-significant-reduction-of-radiation-dosage-in-cardiac-device-implantation-procedures
#3
Rainer Hoffmann, Lukas Langenbrink, Doris Reimann, Mirlind Kastrati, Michael Becker, Michal Piatkowski, Jochen Michaelsen
BACKGROUND: Novel X-ray systems with real-time image noise reduction technology (INRT) to reduce radiation dose during fluoroscopy and cine acquisition have become available. This study evaluated the reduction of radiation dose in device implantation with INRT. METHODS: Radiation dose data from 132 consecutive new device implantation procedures (102 pacemaker (PM) or implantable cardioverter defibrillator (ICD) and 30 cardiac resynchronization therapy (CRT) devices) performed between 1-2015 and 12-2015 on an angiography system with INRT (Allura ClarityIQ) were collected...
October 20, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29052236/heart-failure-severity-inappropriate-icd-therapy-and-novel-icd-programming-a-madit-rit-sub-study
#4
Usama A Daimee, Katherine Vermilye, Spencer Rosero, Claudio D Schuger, James P Daubert, Wojciech Zareba, Scott McNitt, Bronislava Polonsky, Arthur J Moss, Valentina Kutyifa
BACKGROUND: The effects of heart failure (HF) severity on risk of inappropriate implantable cardioverter-defibrillator (ICD) therapy have not been thoroughly investigated. We aimed to study the association between HF severity and inappropriate ICD therapy in MADIT-RIT. METHODS: MADIT-RIT randomized 1500 patients to three ICD programming arms: conventional (Arm A), high-rate cut-off (Arm B: ≥200 bpm), and delayed therapy (Arm C: 60-second delay for ≥170 bpm)...
October 20, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29050686/gender-differences-in-cardiac-resynchronization-therapy-device-choice-and-outcome-in-patients-%C3%A2-75-years-of-age-with-heart-failure
#5
Yanting Wang, Michael S Sharbaugh, Mohammad Bilal Munir, Evan C Adelstein, Norman C Wang, Andrew D Althouse, Samir Saba
Cardiac resynchronization therapy (CRT) is an established therapy for heart failure and can be delivered through a CRT pacemaker (CRT-P) or a CRT defibrillator (CRT-D). CRT-P devices are smaller and less expensive, have better battery longevity, and have been subject to fewer recalls and advisories but cannot deliver high-energy shocks to terminate potentially lethal ventricular arrhythmias. As published guidelines do not distinguish between CRT-P and CRT-D indications, we examined the practice of prescribing these devices in older women and men with heart failure...
September 19, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29048460/cardiovascular-magnetic-resonance-imaging-in-patients-with-cardiac-implantable-electronic-devices-a-device-dependent-imaging-strategy-for-improved-image-quality
#6
Sebastian Hilbert, Cosima Jahnke, Susanne Loebe, Sabrina Oebel, Alexander Weber, Ricardo Spampinato, Sergio Richter, Michael Doering, Andreas Bollmann, Philipp Sommer, Gerhard Hindricks, Ingo Paetsch
Aims: To prospectively determine evaluability of routine cardiovascular magnetic resonance (CMR) diagnostic modules in a referral population of implanted rhythm device all-comers, and to establish a device-dependent CMR imaging strategy to achieve optimal image quality. Methods and results: One hundred and twenty-eight patients with cardiac implantable electronic devices [insertable cardiac monitoring system, n = 14; implantable loop-recorder, n = 21; pacemaker, n = 31; implantable cardioverter-defibrillator (ICD), n = 50; and cardiac resynchronization therapy defibrillator (CRT-D), n = 12] underwent clinically indicated CMR at 1...
October 18, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29047378/comparison-of-strain-parameters-in-dyssynchronous-heart-failure-between-speckle-tracking-echocardiography-vendor-systems
#7
Wouter M van Everdingen, Alexander H Maass, Kevin Vernooy, Mathias Meine, Cornelis P Allaart, Frederik J De Lange, Arco J Teske, Bastiaan Geelhoed, Michiel Rienstra, Isabelle C Van Gelder, Marc A Vos, Maarten J Cramer
BACKGROUND: Although mechanical dyssynchrony parameters derived by speckle tracking echocardiography (STE) may predict response to cardiac resynchronization therapy (CRT), comparability of parameters derived with different STE vendors is unknown. METHODS: In the MARC study, echocardiographic images of heart failure patients obtained before CRT implantation were prospectively analysed with vendor specific STE software (GE EchoPac and Philips QLAB) and vendor-independent software (TomTec 2DCPA)...
October 18, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/29047028/de-novo-implantation-vs-upgrade-cardiac-resynchronization-therapy-a-systematic-review-and-meta-analysis
#8
REVIEW
Annamaria Kosztin, Mate Vamos, Daniel Aradi, Walter Richard Schwertner, Attila Kovacs, Klaudia Vivien Nagy, Endre Zima, Laszlo Geller, Gabor Zoltan Duray, Valentina Kutyifa, Bela Merkely
Patients with conventional pacemakers or implanted defibrillators are often considered for cardiac resynchronization therapy (CRT). Our aim was to summarize the available evidences regarding the clinical benefits of upgrade procedures. A systematic literature search was performed from studies published between 2006 and 2017 in order to compare the outcome of CRT upgrade vs. de novo implantations. Outcome data on all-cause mortality, heart failure events, New York Heart Association (NYHA) Class, QRS narrowing and echocardiographic parameters were analysed...
October 19, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/29045344/atrial-fibrillation-and-cardiac-resynchronization-therapy
#9
Maurizio Gasparini, Paola Galimberti
PURPOSE OF REVIEW: Atrial fibrillation and heart failure are commonly encountered in current clinical practice. This review aims to revisit the complex interaction of these two common situations and the best treatment whenever both occurs, especially focusing on heart failure patients undergoing cardiac resynchronization therapy (CRT). RECENT FINDINGS: It has been recently confirmed that in patients undergoing cardiac resynchronization therapy, 100% biventricular pacing percentage should be pursued...
October 17, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29045311/cardiac-resynchronization-therapy-outcomes-in-patients-with-chronic-heart-failure-cardiac-resynchronization-therapy-with-pacemaker-versus-cardiac-resynchronization-therapy-with-defibrillator
#10
Michael Drozd, John Gierula, Judith E Lowry, Maria F Paton, Eleanor Joy, Haqeel A Jamil, Richard M Cubbon, Mark T Kearney, David A Cairns, Klaus K Witte
AIMS: Cardiac resynchronization therapy (CRT) for chronic heart failure with left ventricular systolic dysfunction (LVSD) consistently improves survival against optimal medical therapy alone. Limited data exist comparing the outcomes between CRT with pacemaker (CRT-P) and with defibrillator (CRT-D). We aimed to investigate the long-term prognosis of patients who received CRT-P or CRT-D. METHODS AND RESULTS: Data were prospectively collected from consecutive patients with standard indications for CRT, who were implanted at a single large tertiary centre between 2008 and 2012...
October 16, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29043465/comparison-of-strain-imaging-techniques-in-crt-candidates-cmr-tagging-cmr-feature-tracking-and-speckle-tracking-echocardiography
#11
Wouter M van Everdingen, Alwin Zweerink, Robin Nijveldt, Odette A E Salden, Mathias Meine, Alexander H Maass, Kevin Vernooy, Frederik J De Lange, Albert C van Rossum, Pierre Croisille, Patrick Clarysse, Bastiaan Geelhoed, Michiel Rienstra, Isabelle C Van Gelder, Marc A Vos, Cornelis P Allaart, Maarten J Cramer
Parameters using myocardial strain analysis may predict response to cardiac resynchronization therapy (CRT). As the agreement between currently available strain imaging modalities is unknown, three different modalities were compared. Twenty-seven CRT-candidates, prospectively included in the MARC study, underwent cardiac magnetic resonance (CMR) imaging and echocardiographic examination. Left ventricular (LV) circumferential strain was analysed with CMR tagging (CMR-TAG), CMR feature tracking (CMR-FT), and speckle tracking echocardiography (STE)...
October 17, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29042422/cardiac-resynchronization-therapy-using-quadripolar-versus-non-quadripolar-left-ventricular-leads-programmed-to-biventricular-pacing-with-single-site-left-ventricular-pacing-impact-on-survival-and-heart-failure-hospitalization
#12
Francisco Leyva, Abbasin Zegard, Tian Qiu, Edmund Acquaye, Gaetano Ferrante, Jamie Walton, Howard Marshall
BACKGROUND: In cardiac resynchronization therapy (CRT), quadripolar (QUAD) left ventricular (LV) leads are less prone to postoperative complications than non-QUAD leads. Some studies have suggested better clinical outcomes. METHODS AND RESULTS: Clinical events were assessed in 847 patients after CRT-pacing or CRT-defibrillation using either QUAD (n=287) or non-QUAD (n=560), programmed to single-site site LV pacing. Over a follow-up period of 3.2 years (median [interquartile range, 1...
October 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29040554/frailty-syndrome-an-emerging-clinical-problem-in-the-everyday-management-of-clinical-arrhythmias-the-results-of-the-european-heart-rhythm-association-survey
#13
Stefano Fumagalli, Tatjana S Potpara, Torben Bjerregaard Larsen, Kristina H Haugaa, Dan Dobreanu, Alessandro Proclemer, Nikolaos Dagres
The age of patients presenting with complex arrhythmias is increasing. Frailty is a multifaceted syndrome characterized by an increased vulnerability to stressors and a decreased ability to maintain homeostasis. The prevalence of frailty is associated with age. The aims of this European Heart Rhythm Association (EHRA) EP Wire survey were to evaluate the proportion of patients with frailty and its influence on the clinical management of arrhythmias. A total of 41 centres-members of the EHRA Electrophysiology Research Network-in 14 European countries completed the web-based questionnaire in June 2017...
October 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29040523/is-the-rapidly-paced-pig-the-optimal-model-for-endocardial-cardiac-resynchronization-therapy-the-author-s-reply
#14
Gerard Amoros-Figueras, Esther Jorge, Jose M Guerra
No abstract text is available yet for this article.
October 12, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29040521/is-the-rapidly-paced-pig-the-optimal-model-for-endocardial-cardiac-resynchronization-therapy
#15
S A Niederer, J Gould, B Sieniewicz, F Prinzen, C A Rinaldi
No abstract text is available yet for this article.
October 12, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29038172/precision-medicine-for-cardiac-resynchronization-predicting-quality-of-life-benefits-for-individual-patients-an-analysis-from-5-clinical-trials
#16
Michael E Nassif, Yuanyuan Tang, John G Cleland, William T Abraham, Cecilia Linde, Michael R Gold, James B Young, J Claude Daubert, Lou Sherfesee, Dan Schaber, Anthony S L Tang, Philip G Jones, Suzanne V Arnold, John A Spertus
BACKGROUND: Clinical trials have established the average benefit of cardiac resynchronization therapy (CRT), but estimating benefit for individual patients remains difficult because of the heterogeneity in treatment response. Accordingly, we created a multivariable model to predict changes in quality of life (QoL) with and without CRT. METHODS AND RESULTS: Patient-level data from 5 randomized trials comparing CRT with no CRT were used to create a prediction model of change in QoL at 3 months using a partial proportional odds model for no change, small, moderate, and large improvement, or deterioration of any magnitude...
October 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29036446/cardiac-resynchronization-therapy-when-no-lateral-pacing-option-exists-vectorcardiographic-guided-non-lateral-left-ventricular-lead-placement-predicts-acute-hemodynamic-response
#17
Stian Ross, Hans Henrik Odland, Alfonso Aranda, Thor Edvardsen, Lars Ove Gammelsrud, Trine Fink Haland, Richard Cornelussen, Einar Hopp, Erik Kongsgaard
Aims: A difficult cardiac resynchronization therapy (CRT) implantation scenario emerges when no lateral pacing option exists. The aim of this study was to explore the effect of biventricular pacing (BIVP) on vectorcardiographic parameters in patients with a non-lateral left ventricular (LV) lead position. We hypothesized that perimeter and area reduction for both the QRS complex and T-wave would predict acute CRT response. Methods and results: Twenty-six patients (14 ischaemic) with a mean age of 63 ± 10 years and standard CRT indication underwent device implantation with continuous LV pressure registration...
September 23, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29036370/estimation-of-the-effects-of-multipoint-pacing-on-battery-longevity-in-routine-clinical-practice
#18
Finn Akerström, Irene Narváez, Alberto Puchol, Marta Pachón, Cristina Martín-Sierra, Moisés Rodríguez-Mañero, Luis Rodríguez-Padial, Miguel A Arias
Aims: Multipoint pacing (MPP) permits simultaneous multisite pacing of the left ventricle (LV); initial studies suggest haemodynamic and clinical benefits over conventional (single LV site) cardiac resynchronization therapy (CRT). The aim of this study was to estimate the impact of MPP activation on battery longevity in routine clinical practice. Methods and results: Patient (n = 46) and device data were collected from two centres at least 3 months after MPP-CRT device implantation...
September 23, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29036292/association-between-implantable-cardioverter-defibrillator-therapy-and-different-lead-positions-in-patients-with-cardiac-resynchronization-therapy
#19
Mads Brix Kronborg, Jens Brock Johansen, Jens Haarbo, Sam Riahi, Berit Thornvig Philbert, Ole Dan Jørgensen, Jens Cosedis Nielsen
Aims: To evaluate the impact of different right and left ventricular lead positions (RV-LP and LV-LP) on the risk of therapy for ventricular tachycardia/ventricular fibrillation in patients with a cardiac resynchronization therapy device (CRT-D). Methods and results: We performed a large nationwide cohort study on patients in Denmark receiving a CRT-D device from 2008 to 2012 from the Danish Pacemaker and implantable cardioverter defibrillator (ICD) registry. Lead positions were registered during the implantation and categorized as anterior/lateral/posterior and basal/mid-ventricular/apical for the LV-LP, and as apical/non-apical for the RV-LP...
September 27, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29034563/heart-failure-study-of-multipoint-pacing-effects-on-ventriculoarterial-coupling-rationale-and-design-of-the-humvee-trial
#20
Christina Chrysohoou, Polychronis Dilaveris, Christos-Konstantinos Antoniou, Ioannis Skiadas, Konstantinos Konstantinou, Konstantinos Gatzoulis, Ioannis Kallikazaros, Dimitrios Tousoulis
Cardiac resynchronization therapy (CRT) is an established therapy for symptomatic heart failure (HF). Unfortunately, many recipients remain nonresponders. Studies have revealed the potential role of multipoint pacing (MPP) in improving response and outcomes. The aim of this study is to compare the effects of MPP against those of standard biventricular pacing (BVP) on (i) ventriculoarterial coupling (VAC) and energy efficiency of the failing heart, (ii) diastolic function, (iii) quality of life, and (iv) NT-proBNP levels and glomerular filtration rate (GFR) during a follow-up of 13 months...
October 15, 2017: Annals of Noninvasive Electrocardiology
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