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https://www.readbyqxmd.com/read/28916535/spinal-cord-perfusion-pressure-predicts-neurologic-recovery-in-acute-spinal-cord-injury
#1
Jordan W Squair, Lise M Bélanger, Angela Tsang, Leanna Ritchie, Jean-Marc Mac-Thiong, Stefan Parent, Sean Christie, Christopher Bailey, Sanjay Dhall, John Street, Tamir Ailon, Scott Paquette, Nicolas Dea, Charles G Fisher, Marcel F Dvorak, Christopher R West, Brian K Kwon
OBJECTIVE: To determine whether spinal cord perfusion pressure (SCPP) as measured with a lumbar intrathecal catheter is a more predictive measure of neurologic outcome than the conventionally measured mean arterial pressure (MAP). METHODS: A total of 92 individuals with acute spinal cord injury were enrolled in this multicenter prospective observational clinical trial. MAP and CSF pressure (CSFP) were monitored during the first week postinjury. Neurologic impairment was assessed at baseline and at 6 months postinjury...
September 15, 2017: Neurology
https://www.readbyqxmd.com/read/28912277/advantages-of-70-kv-ct-angiography-for-the-visualization-of-the-adamkiewicz-artery-comparison-with-120-kv-imaging
#2
S Shimoyama, T Nishii, Y Watanabe, A K Kono, K Kagawa, S Takahashi, K Sugimura
BACKGROUND AND PURPOSE: Preprocedural identification of the Adamkiewicz artery is crucial in patients with aortic diseases. This study aimed to compare 70-kV CTA with conventional 120-kV CTA for the identification of the Adamkiewicz artery, examining differences in radiation dose and image quality. MATERIALS AND METHODS: We retrospectively analyzed 2 equal groups of 60 patients who had undergone 70-kV or 120-kV CTA to detect the Adamkiewicz artery before aortic repair...
September 14, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28895135/paired-associative-stimulation-goes-spinal
#3
Dirk Czesnik, Walter Paulus
Efficiency, reliability and reproducibility of transcranial stimulation (TS) protocols have been refined repeatedly in the past and will continue to be in the future. This article is protected by copyright. All rights reserved.
September 12, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28891546/work-related-musculoskeletal-pain-among-lebanese-dentists-an-epidemiological-study
#4
S Bou Jaoude, N Naaman, E Nehme, J Gebeily, M Daou
INTRODUCTION: The aim of this study was to evaluate the prevalence of musculoskeletal disorders and identify their associated factors among a group of Lebanese dentists. MATERIALS AND METHODS: A total of 314 Lebanese, dentists completed an anonymous questionnaire that focused on occupational health problems. This study was approved by the ethics committee of Saint-Joseph University of Beirut, Lebanon. The statistical analyses were performed using SPSS for windows...
August 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28890869/multifunctional-biomimetic-spinal-cord-new-approach-to-repair-spinal-cord-injuries
#5
REVIEW
Yang Liu, Qian Li, Bin Zhang, De-Xiang Ban, Shi-Qing Feng
The incidence of spinal cord injury (SCI) has been gradually increasing, and the treatment has troubled the medical field all the time. Primary and secondary injuries ultimately lead to nerve impulse conduction block. Microglia and astrocytes excessively accumulate and proliferate to form the glial scar. At present, to reduce the effect of glial scar on nerve regeneration is a hot spot in the research on the treatment of SCI. According to the preliminary experiments, we would like to provide a new bionic spinal cord to reduce the negative effect of glial scar on nerve regeneration...
August 20, 2017: World Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28889721/spinal-myoclonus-responding-to-continuous-intrathecal-morphine-pump
#6
Jung-Eun Ahn, Dallah Yoo, Ki-Young Jung, Jong-Min Kim, Beom Seok Jeon, Myung Chong Lee
Spinal myoclonus is a sudden, brief, and involuntary movement of segmental or propriospinal muscle groups. Spinal myoclonus has occasionally been reported in patients undergoing opioid therapy, but the pathophysiology of opioid-induced myoclonus has not been elucidated yet. Here, we present two patients with spinal segmental myoclonus secondary to ischemic and radiation myelopathy. Conventional medications did not help treat persistent myoclonus in both legs. Continuous intrathecal morphine infusion was implanted for pain control in one patient, which relieved spinal myoclonus entirely...
September 12, 2017: Journal of Movement Disorders
https://www.readbyqxmd.com/read/28886922/lumbar-pseudo-tail-associated-with-dermal-sinus-a-case-report
#7
Alexandra Seromenho-Santos, Rita Valsassina, José Pimentel, José Miguéns, Claudia C Faria
BACKGROUND: Lumbosacral and coccygeal skin covered appendages are a rare malformation, considered human-tails. CASE REPORT: The authors describe the case of a full term newborn girl with lumbar skin appendage and a normal neurologic examination. The magnetic resonance of the spine revealed a dermal sinus continuous with the skin appendage and with extension into to the spinal canal. Due to the infection risk, a surgery was performed on the third day of life, with dermal sinus ligation and appendage removal...
September 5, 2017: Neurocirugía
https://www.readbyqxmd.com/read/28886249/chronic-5-ht-sub-2-sub-receptor-blockade-unmasks-the-role-of-5-ht-sub-1f-sub-receptors-in-the-inhibition-of-the-rat-cardioaccelerator-sympathetic-outflow
#8
José Ángel García-Pedraza, Oswaldo Hernández-Abreu, Mónica García, Asunción Morán, Carlos M Villalón
Serotonin (5-hydroxytryptamine; 5-HT) inhibits the rat cardioaccelerator sympathetic outflow by 5-HT<sub>1B/1D/5</sub> receptors. Since chronic blockade of sympatho-excitatory 5-HT<sub>2</sub> receptors is beneficial in several cardiovascular pathologies, this study investigated whether sarpogrelate (a 5-HT<sub>2</sub> receptor antagonist) alters the pharmacological profile of the above sympatho-inhibition. Rats were pretreated during 2 weeks with sarpogrelate in drinking water (30 mg/kg...
September 8, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28884476/probiotics-for-preventing-urinary-tract-infection-in-people-with-neuropathic-bladder
#9
REVIEW
Swee-Ling Toh, Claire L Boswell-Ruys, Bon San B Lee, Judy M Simpson, Kate R Clezy
BACKGROUND: Neuropathic or neurogenic bladder describes a process of dysfunctional voiding as the result of injury in the brain, spinal cord or nerves innervating the bladder. People with neuropathic bladder, such as from spinal cord injury (SCI), are at significant risk of morbidity from urinary tract infections (UTI). Effective methods to prevent UTI in people with SCI have been sought for many years. Probiotics (micro-organisms that exert beneficial health effects in the host) have been recommended for bacterial interference of the urological tract to reduce colonisation by uropathogen and to manage the dual problems of infection and antibiotic resistance...
September 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28882606/managing-spine-surgery-referrals-the-consultation-of-neurosurgery-and-its-nuances
#10
B Debono, P Sabatier, A Koudsie, K Buffenoir, O Hamel
INTRODUCTION: Spinal disorders, particularly low back pain, are among the most common reasons for general practitioner (GP) consultation and can sometimes be a source of professional friction. Despite their frequency and published guidelines, many patients are still mistakenly referred by their GP to specialists for spinal surgery consultation which can create colleague relationship problems, suboptimal or unnessary delayed care, as well as the financial implications for patients. PURPOSE: To assess the management of GP lumbar spine referrals made to 4 neurosurgeons from 3 neurosurgical teams specialized in spinal surgery...
September 4, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28882348/hemostasis-and-safety-of-a-novel-fibrin-dressing-versus-standard-gauze-in-bleeding-cancellous-bone-in-a-caprine-spine-surgery-model
#11
C Timothy Floyd, Rodolfo A Padua, Curtis E Olson
BACKGROUND: Decorticated bone is a significant source of blood loss in scoliosis surgery. Current hemostatic methods include packed gauze (GS), physical barriers such as bone wax, and xenograft collagen-based materials. We assessed the safety and efficacy of a novel fibrin dressing (dextran-thrombin-fibrinogen [DTF]) compared to GS. This dressing comprises lyophilized thrombin and fibrinogen embedded in an elastic electrospun nanofiber dextran matrix. PURPOSE: The study tests the hypothesis that DTF is more efficacious than GS in control of bleeding from cancellous bone...
September 2017: Spine Deformity
https://www.readbyqxmd.com/read/28880133/epidemiological-study-of-spinal-cord-injury-individuals-from-halfway-houses-in-shanghai-china
#12
Feng-Shui Chang, Qi Zhang, Mei Sun, Hui-Jiong Yu, Long-Jun Hu, Jing-Hua Wu, Gang Chen, Lian-Ding Xue, Jun Lu
OBJECTIVE: To describe the characteristics of spinal cord injury (SCI) individuals in Shanghai and examine their treatment and rehabilitation for traumatic and complete SCI individuals. DESIGN: Community-based secondary data analyses. SETTING: Shanghai, China. METHODS: We analyzed gender, age at injury, complications, disturbances of function, treatment, etiology, and severity of injury of SCI individuals that enrolled in "halfway houses", government-supported community co-op centers...
September 7, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28880132/linking-spinal-cord-injury-rehabilitation-between-the-world-wars-the-r-tait-mckenzie-legacy
#13
John F Ditunno
Spinal cord injury (SCI) medicine emerged after World War II due to mass casualties, which required specialized treatment centers. This approach to categorical care, however, was first developed during World War I, led by pioneers R. Tait McKenzie and George Deaver, who demonstrated that soldiers disabled by paralysis could return to society through fitness/mobility, recreational and vocational training. McKenzie, a Canadian and the first professor of physical therapy in the US, influenced Deaver and military physicians in Britain, Canada, and the U...
September 7, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28875709/continuous-epidural-infusion-versus-programmed-intermittent-epidural-bolus-for-labor-analgesia-optimal-configuration-of-parameters-to-reduce-physician-administered-top-ups
#14
Carlos Delgado, Christopher Ciliberto, Laurent Bollag, Margaret Sedensky, Ruth Landau
BACKGROUND AND OBJECTIVES: Programmed intermittent epidural bolus (PIEB) is a delivery mode associated with decreased local analgesia dosing, motor block, and physician-administered top-ups (PATU) during labor analgesia. We hypothesized that PIEB delivery at different settings will result in fewer PATU for labor analgesia than the same hourly volume of a continuous epidural infusion (CEI). METHODS: 'Before and after' study design of combined-spinal epidural (CSE) for labor, with bupivacaine 0...
September 6, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28874984/neuropathic-pain-after-spinal-surgery
#15
REVIEW
Jae Hwan Cho, Jae Hyup Lee, Kwang-Sup Song, Jae-Young Hong
Neuropathic pain after spinal surgery, the so-called failed back surgery syndrome (FBSS), is a frequently observed troublesome disease entity. Although medications may be effective to some degree, many patients continue experiencing intolerable pain and functional disability. Only gabapentin has been proven effective in patients with FBSS. No relevant studies regarding manipulation or physiotherapy for FBSS have been published. Spinal cord stimulation (SCS) has been widely investigated as a treatment option for chronic neuropathic pain, including FBSS...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28870836/the-patient-s-experience-with-non-surgical-treatment-for-lumbar-spinal-stenosis-a-qualitative-study
#16
Allyn M Bove, Andrew D Lynch, Carlo Ammendolia, Michael Schneider
BACKGROUND CONTEXT: Lumbar spinal stenosis (LSS) is a highly prevalent disease in older adults that causes significant limitations in walking and other daily activities. There is a lack of research into optimal nonsurgical treatment approaches for LSS. PURPOSE: The purpose of this qualitative study is to assess the opinions of participants in a randomized clinical trial of non-surgical LSS treatments regarding the interventions they received, factors contributing to adherence to the interventions, and methods of outcomes assessment...
September 1, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28870357/neurostimulation-devices-for-the-treatment-of-neurologic-disorders
#17
REVIEW
Christine A Edwards, Abbas Kouzani, Kendall H Lee, Erika K Ross
Rapid advancements in neurostimulation technologies are providing relief to an unprecedented number of patients affected by debilitating neurologic and psychiatric disorders. Neurostimulation therapies include invasive and noninvasive approaches that involve the application of electrical stimulation to drive neural function within a circuit. This review focuses on established invasive electrical stimulation systems used clinically to induce therapeutic neuromodulation of dysfunctional neural circuitry. These implantable neurostimulation systems target specific deep subcortical, cortical, spinal, cranial, and peripheral nerve structures to modulate neuronal activity, providing therapeutic effects for a myriad of neuropsychiatric disorders...
September 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28870058/technologically-advanced-assessment-of-upper-limb-spasticity-a-pilot-study
#18
Federico Posteraro, Simona Crea, Stefano Mazzoleni, Mihai Berteanu, Ileana Ciobanu, Nicola Vitiello, Marco Cempini, Sabata Gervasio, Natalie Mrachacz-Kersting
BACKGROUND: Spasticity is a muscle disorder associated with upper motor neuron syndrome occurring in neurological disorders, such as stroke, multiple sclerosis, spinal cord injury and others. It influences the patient's rehabilitation, interfering with function, limiting independence, causing pain and producing secondary impairments, such as contractures or other complications. Due to the heterogeneity of clinical signs of spasticity, there is no agreement on the most appropriate assessment and measurement modality for the evaluation of treatment outcomes...
September 4, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28867993/impact-of-prefrontal-theta-burst-stimulation-on-clinical-neuropsychological-tasks
#19
Raquel Viejo-Sobera, Diego Redolar-Ripoll, Mercè Boixadós, Marc Palaus, Antoni Valero-Cabré, Elena M Marron
Theta burst stimulation (TBS) protocols hold high promise in neuropsychological rehabilitation. Nevertheless, their ability to either decrease (continuous, cTBS) or increase (intermittent, iTBS) cortical excitability in areas other than the primary motor cortex, and their consistency modulating human behaviors with clinically relevant tasks remain to be fully established. The behavioral effects of TBS over the dorsolateral prefrontal cortex (dlPFC) are particularly interesting given its involvement in working memory (WM) and executive functions (EF), often impaired following frontal brain damage...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28866058/surgical-fat-patch-improves-secondary-intracranial-hypotension-orthostatic-headache-associated-with-lumbosacral-dural-ectasia-case-report
#20
Beretta Elena, Franzini Andrea, Cordella Roberto, Nazzi Vittoria, Valentini Laura Grazia, Franzini Angelo
BACKGROUND: Secondary intracranial hypotension is a clinical syndrome associated with the reduction of the cerebrospinal fluid volume and dural continuity violation. The main symptoms are orthostatic headache associated with nausea, vomiting, diplopia, dizziness and tinnitus. The treatment is usually non-specific. CASE DESCRIPTION: The authors describe the case of a 37-years-old woman who developed secondary intracranial hypotension caused by lumbosacral iatrogenic dural ectasia following de-tethering surgery...
August 30, 2017: World Neurosurgery
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