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https://www.readbyqxmd.com/read/29457438/-ct-and-mri-manifestation-of-primary-spinal-large-b-cell-lymphoma
#1
Ping Tian, Kai Jiang, Zhi-Qiang Cai, Yong-Tao Wang, Sheng-de Deng
OBJECTIVE: To investigate CT and MRI characteristics of primary spinal large B cell lymphoma. METHODS: CT and MRI data of 23 patients with primary spinal large B cell lymphoma confirmed by histopathology were retrospectively analyzed from March 2011 to August 2015. Among them, including 14 males and 9 females aged from 28 to 70 years old with an average of 53.4 years old. The clinical manifestation mainly focus on pain around spinal and minority peripheral nerve symptom...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29456757/the-natural-history-of-spinal-deformity-in-patients-with-coffin-lowry-syndrome
#2
M Welborn, S Farrell, P Knott, E Mayekar, S Mardjetko
Purpose: Little is known about the natural history of spinal deformities in Coffin-Lowry syndrome (CLS). Our goal was to evaluate the spinal deformity progression and clinical impact. Methods: In this institutional review board-approved study, we performed a multinational retrospective review of six male CLS patients, aged 13 to 22 years at final follow-up, for a mean of 7.25 years (3 to 13). Results: All showed delayed skeletal maturity. Three had calcifications of their lower cervical ligamentum flavum, all experienced neural axis abnormalities, including lower extremity weakness, numbness and tingling and in one, quadriparesis...
February 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29456756/relationship-between-thoracic-kyphosis-and-neural-axis-abnormalities-in-patients-with-adolescent-idiopathic-scoliosis
#3
I Swarup, P Derman, E Sheha, J Nguyen, J Blanco, R Widmann
Purpose: Previous studies have suggested an association between increased thoracic kyphosis and neural axis abnormalities in patients with adolescent idiopathic scoliosis (AIS). However, the basis for this finding is unclear, and this association has been mainly noted in retrospective studies on a non-consecutive series of patients. The purpose of this study was to assess the relationship between thoracic kyphosis and neural axis abnormalities in patients with AIS. Methods: We studied a consecutive series of AIS patients treated with spinal fusion...
February 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29456443/the-screening-process-of-a-patient-with-low-back-pain-and-suspected-thoracic-myelopathy-a-case-report
#4
Guillaume Christe, Toby Hall
Background: Thoracic disc herniations are rare and difficult to diagnose. Myelopathy is a potential consequence that can lead to irreversible neurological impairment if not treated appropriately. It is incumbent on all clinicians who see patients with low back pain (LBP) to be aware of such pathologies. This case describes a screening process in the detection of a rare serious spinal pathology and discusses the use of red flags and central nervous system signs and symptoms in the decision leading to immediate referral...
February 2018: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/29455490/-clinical-application-of-anterior-thoracoscopically-assisted-surgery-with-posterior-one-stage-total-en-block-spondylectomy-for-thoracic-spinal-tumor
#5
Wen Xue, Xiao-Li Guan, Zeng-Ping Wang, Zhong-Yu Hao, Lin Liu, Yao-Wen Qian
OBJECTIVE: To investigate the clincial effects and feasibility of anterior thoracoscopically assisted surgery (TAS) with posterior one-stage total en block spondylectomy(TES) for thoracic spinal tumour. METHODS: From October 2014 to January 2016, 4 patients with thoracic spinal tumour were treated by anterior thoracoscopically assisted surgery with posterior one-stage total en block spondylectomy. There were 2 males and 2 females, aged 16, 35, 46, 60 years. Courses of disease were 1, 4, 6, 9 months...
September 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29454667/pten-expression-in-astrocytic-processes-after-spinal-cord-injury
#6
T V Povysheva, Y O Mukhamedshina, A A Rizvanov, Y A Chelyshev
The role of the Rho/ROCK/PTEN signaling pathway in the regulation of astrocyte function for consolidation/stabilization of the synapse has not been thoroughly studied. In this study, the expression of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) in GFAP-positive astrocytic processes in the ventral horns (VH) of the rat spinal cord has been evaluated in the normal condition and in a delayed period (30 days) after dosed contusion spinal cord injury (SCI) in caudal thoracic segments. In intact rats and at 30 days post-injury (dpi), semi-quantitative immunohistochemical analysis showed that there is approximately 2 folds less synaptophysin reactivity in the motoneuron perikarya than outside the perikarya, i...
February 15, 2018: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/29454133/prevalence-and-risk-factors-for-neural-axis-anomalies-in-idiopathic-scoliosis-a-systematic-review
#7
REVIEW
Johan L Heemskerk, Moyo C Kruyt, Dino Colo, René M Castelein, Diederik H R Kempen
BACKGROUND: There is ongoing controversy about the routine use of magnetic resonance imaging (MRI) preoperatively in patients with presumed idiopathic scoliosis (IS). Routine MRI can help identify possible causes for the deformity and detect anomalies which could complicate deformity surgery. However, routine MRI increases health care costs significantly and may reveal mild variations from normal without clinical relevance, that can still lead to anxiety and influence decision making...
February 14, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29454122/rope-jumping-induced-traumatic-compression-fractures-the-underestimated-danger-of-repetitive-axial-load-forces
#8
Tobias A Mattei
The author describes a case of a non-osteoporotic adult presenting with multilevel compression fractures at the apex of the thoracic kyphosis after strenuous rope jumping. MRI demonstrated diffuse bone marrow changes in the vertebral bodies with only a very small unilateral endplate fracture. Besides highlighting the oftentimes neglected role of repetitive sub-pathological axial load forces in traumatic spinal injuries, the observed imaging pattern substantiates previous experimental studies which demonstrated that under cyclic axial loading the initial damage occurs in the cancellous regions of the bone (with observation of microscopic/50-100 μM long cracks), ultimately leading to a reduction in its elastic modulus...
February 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29448993/adjacent-level-spondylodiscitis-in-a-patient-with-thoracic-spondylodiscitis-a-case-report-and-review-of-the-literature
#9
K Farah, T Graillon, H Dufour, S Fuentes
INTRODUCTION: Adjacent level spondylodiscitis (ALS) after primary surgery for thoracic spondylodiscitis is a very rare condition. CASE REPORT: We report the case of a 76-year-old man with this pathology. A first posterior minimally invasive approach combined with anterior approach to the thoracic spine was safely performed for thoracic spondylodiscitis. More than a year later, exploration of recurrent symptoms with 18 FDG PET scan helped to diagnose ALS. Further surgery was performed...
February 12, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29447489/compulsory-use-of-the-backboard-is-associated-with-increased-frequency-of-thoracolumbar-imaging
#10
Brian M Clemency, Christopher T Tanski, Jennifer Gibson Chambers, Michael O'Brien, Andrew S Knapp, Alexander J Clark, Patrick McGoff, Johanna Innes, Heather A Lindstrom, David Hostler
BACKGROUND: Backboards have been shown to cause pain in uninjured patients. This may alter physical exam findings, leading emergency department (ED) providers to suspect a spinal injury when none exists resulting in additional imaging of the thoracolumbar spine. New York had previously employed a "Spinal Immobilization" protocol that included compulsory backboard application for all patients with suspected spinal injuries. In 2015, New York instituted a new "Spinal Motion Restriction" protocol that made backboard use optional for these patients...
February 15, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29445966/thoracic-ossification-of-ligamentum-flavum-manifesting-holocord-syringomyelia-case-report
#11
Yoshiaki Takamura, Yasuhiro Takeshima, Ryuta Matsuoka, Young Soo Park, Hiroyuki Nakase
It has been reported that syringomyelia is rarely associated with degenerative spinal disorders, but the case of holocord syringomyelia is never reported. We here present a case of a 59-year-old woman with right shoulder pain, dysesthesia of the right hand, and gait disturbance. Radiographically, examinations of the spine demonstrated holocord syringomyelia with ossification of ligamentum flavum at T2/3 level. Holocord syringomyelia was reduced remarkably after posterior decompression at the T2/3 level, and her symptoms also improved...
February 14, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29445948/intraspinal-neural-axis-abnormalities-in-severe-spinal-deformity-a-10-year-mri-review
#12
Ying Zhang, Jingming Xie, Yingsong Wang, Ni Bi, Tao Li, Jie Zhang, Zhi Zhao, Hua Ou, Siyuan Liu
PURPOSE: Documents indicated that the average prevalence of intraspinal neural axis abnormalities (INAAs) in presumed idiopathic scoliosis (PIS) patients was about 17.7%. However, paucity study focuses on the incidence of INAAs in severe spinal deformity (SSDs). In this study, we investigate the incidence of intraspinal neural axis abnormalities (IINAAs) and the clinical relevance in SSD at a single center. METHODS: All the patients with SSDs admitted for spinal surgery were evaluated from 2003 to 2014...
February 14, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29445946/paravertebral-tumours-of-the-cervicothoracic-junction-extending-into-the-mediastinum-surgical-strategies-in-a-no-man-s-land
#13
Georgios K Prezerakos, Parag Sayal, Antonios Kourliouros, Periclis Pericleous, George Ladas, Adrian Casey
PURPOSE: Cervicothoracic paravertebral neoplasms extending into the mediastinum pose a surgical challenge due the complex regional anatomy, their biological nature, rarity and surgeon's unfamiliarity with the region. We aim to define a surgical access framework addressing the aforementioned complexities whilst achieving oncological clearance. METHODS: We carried out a retrospective review of 28 consecutive patients operated in two tertiary referral centres between 1998 and 2015...
February 14, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29445509/a-case-of-paraplegia-that-developed-6-years-after-thoracic-endovascular-aortic-repair-for-blunt-traumatic-aortic-injury
#14
Hiroyuki Takahashi, Tomohisa Shoko, Fumino Taketazu, Keiichi Kuriyama, Kazuhide Yoshikawa, Yoshizumi Deguchi
Case: Thoracic endovascular aortic repair (TEVAR) is becoming the standard therapy for blunt thoracic aortic injury (BTAI). However, the long-term outcomes of TEVAR for BTAI remain unclear. A 36-year-old man was admitted to our emergency department with dyspnea. He had been involved in a serious traffic accident 6 years earlier, requiring TEVAR for BTAI. Outcome: Acute heart failure and pneumonia were diagnosed on this admission. His respiratory condition improved, but paraplegia developed 10 h after hospitalization...
January 2018: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29441246/spinal-cord-infarction-mimicking-acute-transverse-myelitis
#15
Nilesh H Pawar, Ealing Loke, Derrick C Aw
Spinal cord infarction (SCI) is a rare type of stroke. The initial magnetic resonance imaging (MRI) is usually normal and can mimic the presentation of the acute transverse myelitis (ATM), acute inflammatory demyelinating polyneuropathy, and compressive myelopathies from neoplasm, epidural or subdural hematoma, or abscess. The aim of this report is to describe and discuss the case of a patient with SCI presenting as a diagnostic confusion with acute transverse myelitis. A 64-year-old male with a medical history of hypertension presented with an acute onset of urinary retention with lower limb weakness...
December 6, 2017: Curēus
https://www.readbyqxmd.com/read/29435500/three-dimensional-reconstructions-of-lenke-1a-curves
#16
J-C Bernard, E Berthonnaud, J Deceuninck, L Journoud-Rozand, G Notin, E Chaleat-Valayer
Background: Scoliosis is a 3D deformity that can be reconstructed through 2D antero-posterior and lateral radiographs, which provide an upper view of the deformed spine as well as regional planes matching all vertebrae of elective plane for each curve. The objective of this study is to explore whether all idiopathic scoliosis classified Lenke 1A have the same 3D representation made with regional planes. Methods: All patients treated for idiopathic thoracic scoliosis during the growth period and classified Lenke 1A were included in this study conducted in the pediatric spinal orthopedic department of Centre des Massues...
2018: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/29434866/logistic-regression-analysis-of-risk-factors-for-postoperative-recurrence-of-spinal-tumors-and-analysis-of-prognostic-factors
#17
Shanyong Zhang, Lili Yang, Chuangang Peng, Minfei Wu
The aim of the present study was to investigate the risk factors for postoperative recurrence of spinal tumors by logistic regression analysis and analysis of prognostic factors. In total, 77 male and 48 female patients with spinal tumor were selected in our hospital from January, 2010 to December, 2015 and divided into the benign (n=76) and malignant groups (n=49). All the patients underwent microsurgical resection of spinal tumors and were reviewed regularly 3 months after operation. The McCormick grading system was used to evaluate the postoperative spinal cord function...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29434464/arm-cycling-combined-with-passive-leg-cycling-enhances-vo2peak-in-persons-with-spinal-cord-injury-above-the-sixth-thoracic-vertebra
#18
Tom Tørhaug, Berit Brurok, Jan Hoff, Jan Helgerud, Gunnar Leivseth
Objective: To test whether passive leg cycling (PLC) during arm cycling ergometry (ACE) affects peak oxygen uptake (VO2peak) differently in individuals with spinal cord injury (SCI) at/above the 6th thoracic vertebra (T6) and below T6. Methods: We conducted a cross-sectional study, analyzed by univariate and multivariate regression models. Between- and within-group differences were examined during (a) ACE only, (b) ACE combined with PLC (ACE-PLC), and (c) ACE combined with functional electrical stimulation cycling (FES hybrid)...
2018: Topics in Spinal Cord Injury Rehabilitation
https://www.readbyqxmd.com/read/29433818/spinal-adhesive-arachnoiditis-following-the-rupture-of-an-adamkiewicz-aneurysm-literature-review-and-a-case-illustration
#19
REVIEW
J Todeschi, S Chibbaro, A Gubian, R Pop, F Proust, H Cebula
BACKGROUND: The rupture of an isolated spinal aneurysm is an exceptional occurrence. It might be responsible for a spinal subarachnoid haemorrhage (SSAH) that in rare cases can be complicated by arachnoiditis. Among the former the adhesive type is the most severe leading to the formation of a cyst and/or a syrinx. PATIENTS AND METHODS: The literature review was performed via a PubMed search using the following keywords. Adhesive arachnoiditis; spinal subarachnoid haemorrhage; spinal arachnoiditis; spinal arachnoid cyst; arachnoid cyst ...
February 9, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29432301/adenovirus-delivered-gfp-ho-1c-increment-23-attenuates-blood-spinal-cord-barrier-permeability-after-rat-spinal-cord-contusion
#20
Sheng Chang, Yunlong Bi, Xiangwei Meng, Lin Qu, Yang Cao
The blood-spinal cord barrier (BSCB) plays a key role in maintaining the microenvironment and is primarily composed of tight junction proteins and nonfenestrated capillary endothelial cells. After injury, BSCB damage results in increasing capillary permeability and release of inflammatory factors. Recent studies have reported that haem oxygenase-1 (HO-1) fragments lacking 23 amino acids at the C-terminus (HO-1C[INCREMENT]23) exert novel anti-inflammatory and antioxidative effects in vitro. However, no study has identified the role of HO-1C[INCREMENT]23 in vivo...
February 9, 2018: Neuroreport
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