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https://www.readbyqxmd.com/read/29718336/a-clinical-decision-support-system-algorithm-for-intravenous-to-oral-antibiotic-switch-therapy-validity-clinical-relevance-and-usefulness-in-a-three-step-evaluation-study
#1
H Akhloufi, M Hulscher, C P van der Hoeven, J M Prins, H van der Sijs, D C Melles, A Verbon
Objectives: To evaluate a clinical decision support system (CDSS) based on consensus-based intravenous to oral switch criteria, which identifies intravenous to oral switch candidates. Methods: A three-step evaluation study of a stand-alone CDSS with electronic health record interoperability was performed at the Erasmus University Medical Centre in the Netherlands. During the first step, we performed a technical validation. During the second step, we determined the sensitivity, specificity, negative predictive value and positive predictive value in a retrospective cohort of all hospitalized adult patients starting at least one therapeutic antibacterial drug between 1 and 16 May 2013...
April 26, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29701797/commentary-on-appropriate-use-criteria-for-sij-pain
#2
Mark Laslett
No abstract text is available yet for this article.
April 26, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29690728/-efficacy-of-yisaipu-tapering-in-the-treatment-of-ankylosing-spondylitis
#3
Z X Huang, X Q Guo, W M Deng, S L Zheng, X Guo, Y K Huang, T W Li
Objective: To assess the efficacy of Yisaipu tapering in patients with ankylosing spondylitis (AS). Methods: A total of 87 cases of AS patients from Guangdong Second Provincial General Hospital who were treated with Yisaipu and celecoxib were retrospectively analyzed from February 2013 to April 2017.All patients received full dose Yisaipu and celecoxib in the initial 12 weeks.After that, the patients in the full dose group maintained Yisaipu (50 mg/w) treatment from the 13(rd) to 24(th) week, while tapering group received Yisaipu 50 mg subcutaneous injection once every other week...
April 17, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29678187/an-unexpected-cause-of-sacroiliitis-in-a-patient-with-gout-and-chronic-psoriasis-with-inflammatory-arthritis-a-case-report
#4
Safi Alqatari, Roberta Visevic, Nina Marshall, John Ryan, Grainne Murphy
BACKGROUND: Inflammatory back pain is a condition characterized by inflammation of the sacroiliac joints and lower spine. It is frequently seen in patients with spondyloarthropathies like ankylosing spondylitis, psoriatic arthritis, enteropathic arthritis and reactive arthritis. Inflammatory back pain can be caused by many other conditions like infection and crystal deposition such as gout. In this case, it is difficult to specifically identify gout as a cause by ordinary imaging like magnetic resonance imaging (MRI) or ultrasound...
April 20, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29674852/long-term-prospective-outcomes-after-minimally-invasive-trans-iliac-sacroiliac-joint-fusion-using-triangular-titanium-implants
#5
Emily Darr, S Craig Meyer, Peter G Whang, Don Kovalsky, Clay Frank, Harry Lockstadt, Robert Limoni, Andy Redmond, Philip Ploska, Michael Y Oh, Daniel Cher, Abhineet Chowdhary
Background: Minimally invasive sacroiliac joint fusion (SIJF) has become an increasingly accepted surgical option for chronic sacroiliac (SI) joint dysfunction, a prevalent cause of unremitting low back/buttock pain. Objective: The objective of this study was to report clinical and functional outcomes of SIJF using triangular titanium implants (TTI) in the treatment of chronic SI joint dysfunction due to degenerative sacroiliitis or sacroiliac joint (SIJ) disruption at 3 years postoperatively...
2018: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29672748/biopsychosocial-profiles-and-functional-correlates-in-older-adults-with-chronic-low-back-pain-a-preliminary-study
#6
Debra K Weiner, Angela Gentili, Katherine Coffey-Vega, Natalia Morone, Michelle Rossi, Subashan Perera
Objective: To describe key peripheral and central nervous system (CNS) conditions in a group of older adults with chronic low back pain (CLBP) and their association with pain severity and self-reported and performance-based physical function. Design: Cross-sectional. Setting: Outpatient VA clinics. Subjects: Forty-seven community-dwelling veterans with CLBP (age 68.0 ± 6.5 years, range = 60-88 years, 12.8% female, 66% white) participated...
April 16, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29666994/whole-body-mri-in-spondyloarthritis-spa-preliminary-results-suggest-that-dwi-outperforms-stir-for-lesion-detection
#7
Frederic E Lecouvet, Nicolas Vander Maren, Laurence Collette, Nicolas Michoux, Perrine Triqueneaux, Maria Stoenoiu, Frederic Houssiau, Jacques Malghem, Marie-Laurence Denis, Ahmed Larbi, Adrien Nzeusseu Toukap
PURPOSE: To compare the diagnostic accuracy of DWI and STIR sequences in Whole body (WB) MRI of SpA patients. MATERIALS AND METHODS: Twenty consecutive patients with confirmed active SpA and 20 controls were investigated with identical WB MRI protocols, including DWI and STIR images. Two observers recorded 'lesions' (high signal intensity foci on STIR and high b-value DWI) in 17 anatomical areas, making a 17-point 'area score' and a 40-point 'lesion score'. ROC performance, inter-observer agreement, correlation with clinical parameters and spine and sacro-iliac joints (SIJ) MRI scores were assessed...
April 17, 2018: European Radiology
https://www.readbyqxmd.com/read/29664756/mri-in-spondyloarthritis-when-and-how
#8
Georg Kröber, Ulrich Weber
PURPOSE OF REVIEW: To summarize recent advances and challenges of using MRI toward early recognition of axial spondyloarthritis (SpA). RECENT FINDINGS: Low-grade bone marrow edema (BME) on sacroiliac joint (SIJ) MRI is nonspecific and may be misleading in recognition of axial SpA. Structural features on SIJ MRI along with BME may not only facilitate recognition of early disease, but also enhance specificity. Structural lesions on MRI and low-dose computed tomography are highly concordant, adding to criterion validity of SIJ MRI...
April 13, 2018: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/29587851/clinical-and-mri-remission-in-patients-with-nonradiographic-axial-spondyloarthritis-who-received-long-term-open-label-adalimumab-treatment-3-year-results-of-the-ability-1-trial
#9
Désirée van der Heijde, Joachim Sieper, Walter P Maksymowych, Robert G Lambert, Su Chen, Maja Hojnik, Jaclyn K Anderson, Aileen L Pangan
BACKGROUND: Adalimumab was effective in treating patients with nonradiographic axial spondyloarthritis (nr-axSpA) in the 12-week ABILITY-1 trial. We present long-term efficacy and safety results of adalimumab from the open-label ABILITY-1 extension, including the relationship between clinical and magnetic resonance imaging (MRI) remission and impact of sustained clinical remission on physical function. METHODS: Patients received adalimumab 40 mg every other week or placebo for 12 weeks, then open-label adalimumab for up to 144 weeks...
March 27, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29549893/effect-of-sacroiliac-joint-mobilization-on-the-level-of-soft-tissue-pain-threshold-in-asymptomatic-women
#10
Tomasz Sipko, Adam Paluszak, Agnieszka Siudy
OBJECTIVE: This study aimed to evaluate the effect of sacroiliac joint (SIJ) mobilization and/or self-mobilization on the level of soft tissue pain threshold in 21- to 23-year-old asymptomatic women (n = 20). METHODS: The FPIX Wagner Algometer was applied to compute the pressure pain threshold (PPT) over the right and left side of the iliolumbar ligament and lumbar erector spinae (L3). Measurements were taken of the right SIJ before and after a randomized protocol of oscillating mobilization, self-mobilization, and placebo treatment...
March 2018: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29538011/computed-tomography-in-axial-spondyloarthritis
#11
Sovira Tan, Michael M Ward
PURPOSE OF REVIEW: Computed tomography (CT) is increasingly being used in ankylosing spondylitis (AS) for imaging the spine and sacroiliac joint (SIJ). We review new insights to diagnosis and evaluation revealed by the use of CT. RECENT FINDINGS: Studies using low-dose CT in AS to detect syndesmophytes can image the entire spine, but semiquantitative scoring of the scans by human readers decreases the reliability and validity of this method. The thoracic spine is the segment most involved with syndesmophytes...
March 13, 2018: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/29532415/in-vitro-git-tolerance-of-microencapsulated-bifidobacterium-bifidum-atcc-35914-using-polysaccharide-protein-matrix
#12
Rabia Iqbal, Tahir Zahoor, Nuzhat Huma, Amer Jamil, Gülhan Ünlü
Longevity of probiotic is the main concern for getting maximum benefits when added in food product. Bifidobacterium, a probiotic, tends to lose its viability during gastrointestinal track (GIT) transit and storage of food. Their viability can be enhanced through microencapsulation technology. In this study, Bifidobacterium bifidum (B. bifidum) ATCC 35914 was encapsulated by using two experimental plans. In the first plan, chitosan (CH) at 0.6, 0.8, and 1.0% and sodium alginate (SA) at 4, 5, and 6% were used...
March 12, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29509655/gender-specific-sacroiliac-joint-biomechanics-during-standing-upright-a-finite-element-study
#13
Amin Joukar, Anoli Shah, Ali Kiapour, Ardalan Seyed Vosoughi, Bradley Duhon, Anand K Agarwal, Hossein Elgafy, Nabil Ebraheim, Vijay K Goel
STUDY DESIGN: The comparison of sacroiliac joint (SIJ) angular motions, pelvis ligaments strain, load sharing, and stress distribution across the joint for male and female spine-pelvis-femur models using finite element analysis. OBJECTIVE: To quantify biomechanical parameters at SIJ for all motions for both male and female models. SUMMARY OF BACKGROUND DATA: SIJ has been recognized as a main source of pain in 13% to 30% of patients with low back pain...
March 5, 2018: Spine
https://www.readbyqxmd.com/read/29481980/biomechanical-evaluation-of-sacroiliac-joint-fixation-with-decortication
#14
Yushane C Shih, Brian P Beaubien, Qingshan Chen, Jonathan N Sembrano
BACKGROUND CONTEXT: Fusion typically consists of joint preparation, grafting, and rigid fixation. Fusion has been successfully used to treat symptomatic disruptions of the sacroiliac joint (SIJ) and degenerative sacroiliitis using purpose-specific, threaded implants. The biomechanical performance of these systems is important but has not been studied. PURPOSE: The objective of this study was to compare two techniques for placing primary (12.5 mm) and secondary (8...
February 23, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29479474/mri-for-diagnosis-of-axial-spondyloarthritis-major-advance-with-critical-limitations-not-everything-that-glisters-is-gold-standard
#15
REVIEW
Cédric Lukas, Catherine Cyteval, Maxime Dougados, Ulrich Weber
Recognition of axial spondyloarthritis (SpA) remains challenging, as no unique reference standard is available to ascertain diagnosis. Imaging procedures have been used for long in the field, in particular pelvic radiography, to capture structural changes evocative of sacroiliitis, the key feature in SpA. The introduction of MRI of the sacroiliac joints (SIJs) has led to a major shift in recognition of the disorder. MRI has been shown to detect the initial inflammatory processes, in particular osteitis depicted by bone marrow oedema, even in patients having not yet developed structural lesions...
2018: RMD Open
https://www.readbyqxmd.com/read/29430880/frequency-and-anatomic-distribution-of-magnetic-resonance-imaging-features-in-the-sacroiliac-joints-of-young-athletes-exploring-background-noise-toward-a-data-driven-definition-of-sacroiliitis-in-early-spondyloarthritis
#16
Ulrich Weber, Anne Grethe Jurik, Anna Zejden, Ejnar Larsen, Steen Hylgaard Jørgensen, Kaspar Rufibach, Christian Schioldan, Søren Schmidt-Olsen
OBJECTIVE: Low-grade bone marrow edema (BME) has been reported in the sacroiliac (SI) joints of 25% of healthy individuals and patients with nonspecific mechanical back pain, thus challenging the specificity and predictive value of magnetic resonance imaging (MRI) for the discrimination of early spondyloarthritis (SpA). It is unknown whether stress injury in competition sports may trigger BME. This study sought to explore the frequency and anatomic distribution of SI joint MRI lesions in recreational and elite athletes...
May 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29430266/minimally-invasive-sacroiliac-joint-fusion-2-year-radiographic-and-clinical-outcomes-with-a-principles-based-sij-fusion-system
#17
William W Cross, Arnold Delbridge, Donald Hales, Louis C Fielding
Background: Sacroiliac joint (SIJ) degeneration is a common source of low back pain (LBP). Minimally invasive (MI) SIJ fusion procedures have demonstrated meaningful clinical improvement. A recently developed MI SIJ fusion system incorporates decortication, placement of bone graft and fixation with threaded implants (DC/BG/TF). Patients and Methods: Nineteen patients who had MI SIJ fusion with DC/BG/TF were enrolled at three centers. Fusion was assessed in CT images obtained 12 and 24 months postoperatively by an independent radiographic core laboratory...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29419679/the-efficacy-and-safety-of-using-cooled-radiofrequency-in-treating-chronic-sacroiliac-joint-pain-a-prisma-compliant-meta-analysis
#18
Hui-Hui Sun, Su-Yang Zhuang, Xin Hong, Xin-Hui Xie, Lei Zhu, Xiao-Tao Wu
BACKGROUND: Cooled radiofrequency procedure is a novel minimally invasive surgical technique and has been occasionally utilized in managing chronic sacroiliac joint (SIJ) pain. A meta-analysis was conducted to systematically assess the efficacy and safety of using cooled radiofrequency in treating patients with chronic SIJ pain in terms of pain and disability relief, patients' satisfaction degree as well as complications. METHODS: Studies of using cooled radiofrequency procedure in managing SIJ pain were retrieved from Medline and Web of Science according to inclusion and exclusion criteria...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29416268/robot-assisted-ureteral-reconstruction-current-status-and-future-directions
#19
REVIEW
Paurush Babbar, Nitin Yerram, Andrew Sun, Sij Hemal, Prithvi Murthy, Darren Bryk, Naveen Nandanan, Yaw Nyame, Maxx Caveney, Ryan Nelson, Ryan Berglund
Robotic surgery in the treatment in certain urological diseases has become a mainstay. With the increasing use of the robotic platform, some surgeries which were historically performed open have transitioned to a minimally invasive technique. Recently, the robotic approach has become more utilized for ureteral reconstruction. In this article, the authors review the surgical techniques for a number of major ureteral reconstuctive surgeries and briefly discuss the outcomes reported in the literature.
January 2018: Urology Annals
https://www.readbyqxmd.com/read/29415262/anatomical-comparison-of-radiofrequency-ablation-techniques-for-sacroiliac-joint-pain
#20
Shannon L Roberts, Alison Stout, Eldon Y Loh, Nathan Swain, Paul Dreyfuss, Anne M Agur
Objective: To compare the percentage of sacral lateral branches (LBs) that would be captured if lesions were created by seven current sacroiliac joint (SIJ) radiofrequency ablation (RFA) techniques: three monopolar and four bipolar. Design: Cadaveric fluoroscopy study. Setting: Anatomy and surgical skills laboratories. Subjects: Forty cadaveric SIJs. Methods: LBs were exposed, radiopaque wires were sutured to LBs, and anterior-posterior fluoroscopic images through the S1 superior endplate were obtained...
February 5, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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