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https://www.readbyqxmd.com/read/29223113/comparisons-of-severity-classification-systems-for-oropharyngeal-dysfunction-in-children-with-cerebral-palsy-relations-with-other-functional-profiles
#1
Yu-Ra Goh, Ja Young Choi, Seon Ah Kim, Jieun Park, Eun Sook Park
This study aimed to investigate the relationships between various classification systems assessing the severity of oropharyngeal dysphagia and communication function and other functional profiles in children with cerebral palsy (CP). This is a prospective, cross-sectional, study in a university-affiliated, tertiary-care hospital. We recruited 151 children with CP (mean age 6.11 years, SD 3.42, range 3-18yr). The Eating and Drinking Ability Classification System (EDACS) and the dysphagia scales of Functional Oral Intake Scale (FOIS), Swallow Function Scales (SFS), and Food Intake Level Scale (FILS) were used...
December 6, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29215821/a-fast-3-dimensional-magnetic-resonance-imaging-reconstruction-for-surgical-planning-of-uterine-myomectomy
#2
Sa Ra Lee, Young Jae Kim, Kwang Gi Kim
BACKGROUND: Uterine myoma is the most common benign gynecologic tumor in reproductive-aged women. During myomectomy for women who want to preserve fertility, it is advisable to detect and remove all myomas to decrease the risk of additional surgery. However, finding myomas during surgery is often challenging, especially for deep-seated myomas. Therefore, three-dimensional (3D) preoperative localization of myomas can be helpful for the surgical planning for myomectomy. However, the previously reported manual 3D segmenting method takes too much time and effort for clinical use...
January 8, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29211321/recovery-mechanism-of-degraded-black-phosphorus-field-effect-transistors-by-1-2-ethanedithiol-chemistry-and-extended-device-stability
#3
Do-Hyun Kwak, Hyun-Soo Ra, Jinhoon Yang, Min-Hye Jeong, A-Young Lee, Wonki Lee, Jun Yeon Hwang, Joo-Hyoung Lee, Jong-Soo Lee
Black phosphorus (BP) has drawn enormous attention for both intriguing material characteristics and electronic and optoelectronic applications. In spite of excellent advantages for semiconductor device applications, the performance of BP devices is hampered by the formation of phosphorus oxide on the BP surface under ambient conditions. It is thus necessary to resolve the oxygen-induced degradation on the surface of BP to recover the characteristics and stability of the devices. To solve this problem, it is demonstrated that a 1,2-ethanedithiol (EDT) treatment is a simple and effective way to remove the bubbles formed on the BP surface...
December 6, 2017: Small
https://www.readbyqxmd.com/read/29210204/validation-and-reliability-of-the-timed-up-and-go-test-for-measuring-objective-functional-impairment-in-patients-with-long-standing-rheumatoid-arthritis-a-cross-sectional-study
#4
Toshihisa Kojima, Hajime Ishikawa, Sakae Tanaka, Nobuhiko Haga, Keiichiro Nishida, Masao Yukioka, Jun Hashimoto, Hisaaki Miyahara, Yasuo Niki, Tomoatsu Kimura, Hiromi Oda, Shuji Asai, Koji Funahashi, Masayo Kojima, Naoki Ishiguro
AIM: This study aimed to validate the Timed Up and Go test (TUG) for measuring objective functional impairment in patients with established rheumatoid arthritis (RA) based on a prospective observational cohort of RA patients undergoing joint surgery. METHODS: We collected data on demographics, Health Assessment Questionnaire Disability Index (HAQ-DI), and associations between TUG and HAQ-DI and other patient-reported outcomes, including European Quality of life scale (EQ-5D) were determined...
December 5, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29206093/the-clinical-effectiveness-and-cost-effectiveness-of-treat-to-target-strategies-in-rheumatoid-arthritis-a-systematic-review-and-cost-effectiveness-analysis
#5
Allan Wailoo, Emma S Hock, Matt Stevenson, Marrissa Martyn-St James, Andrew Rawdin, Emma Simpson, Ruth Wong, Naila Dracup, David L Scott, Adam Young
BACKGROUND: Treat to target (TTT) is a broad concept for treating patients with rheumatoid arthritis (RA). It involves setting a treatment target, usually remission or low disease activity (LDA). This is often combined with frequent patient assessment and intensive and rapidly adjusted drug treatment, sometimes based on a formal protocol. OBJECTIVE: To investigate the clinical effectiveness and cost-effectiveness of TTT compared with routine care. DATA SOURCES: Databases including EMBASE and MEDLINE were searched from 2008 to August 2016...
November 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29200912/biphasic-augmentation-of-alpha-adrenergic-contraction-by-plumbagin-in-rat-systemic-arteries
#6
Hae Jin Kim, Hae Young Yoo, Yin Hua Zhang, Woo Kyung Kim, Sung Joon Kim
Plumbagin, a hydroxy 1,4-naphthoquinone compound from plant metabolites, exhibits anticancer, antibacterial, and antifungal activities via modulating various signaling molecules. However, its effects on vascular functions are rarely studied except in pulmonary and coronary arteries where NADPH oxidase (NOX) inhibition was suggested as a mechanism. Here we investigate the effects of plumbagin on the contractility of skeletal artery (deep femoral artery, DFA), mesenteric artery (MA) and renal artery (RA) in rats...
November 2017: Korean Journal of Physiology & Pharmacology
https://www.readbyqxmd.com/read/29200759/increased-skin-irritation-by-hydroquinone-and-rsetinoic-acid-used-in-combination
#7
Gwang Hoon Kim, Kyung Ah Cheong, Ai-Young Lee
Background: Hydroquinone (HQ) is frequently combined with retinoic acid (RA) to enhance lightening efficacy, which may also affect skin irritancy. Although skin irritation leads to postinflammatory hyperpigmentation, little research has been performed to compare skin irritancy between each component and the combination. Objective: This study was done to examine whether HQ-RA combination increased skin irritation induced by HQ or RA alone. Methods: Patch testing was performed using maximum therapeutic and higher concentrations of HQ and RA in 10 volunteers, and then, it was performed using their popular therapeutic concentrations and combination in the other 20 volunteers...
December 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/29196384/trends-in-joint-replacement-surgery-in-patients-with-rheumatoid-arthritis
#8
Bradley L Young, Shawna L Watson, Jorge L Perez, Gerald McGwin, Jasvinder A Singh, Brent A Ponce
OBJECTIVE: This study analyzed trends in large total joint arthroplasties (TJA) and in the proportion of these procedures performed on patients with rheumatoid arthritis (RA). METHODS: The US Nationwide Inpatient Sample (2002-2012) was used to identify the incidences of total shoulder (TSA), elbow (TEA), knee (TKA), hip (THA), and ankle (TAA) arthroplasty and the proportion of these performed with coexisting RA. RESULTS: The prevalence of RA among patients with TJA increased 3...
December 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/29193612/a-direct-role-for-hepatitis-b-virus-x-protein-in-inducing-mitochondrial-membrane-permeabilization
#9
Hye-Ra Lee, Young Youn Cho, Gi Young Lee, Deok-Gyun You, Young Do Yoo, Yoon Jun Kim
Hepatitis B virus X protein (HBx) acts as a multifunctional protein that regulates intracellular signaling pathways during HBV infection. It has mainly been studied in terms of its interaction with cellular proteins. Here, we show that HBx induces membrane permeabilization independently of the mitochondrial permeability transition pore complex. We generated mitochondrial outer membrane-mimic liposomes to observe the direct effects of HBx on membranes. We found that HBx induced membrane permeabilization, and the region comprising the transmembrane domain and the mitochondrial targeting sequence was sufficient for this process...
November 28, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29189308/lactotripeptides-supplementations-alleviate-the-decrease-in-maximal-isometric-force-following-high-intensity-eccentric-exercise-a-randomized-placebo-controlled-double-blinded-clinical-trial
#10
Kaname Tagawa, Song-Gyu Ra, Youngju Choi, Seiji Maeda
OBJECTIVE: To investigate whether lactotripeptides (LTP) supplementations alleviate the decrease in the maximal isometric force (MIF), an indirect marker of muscle damage, following eccentric exercise (ECC). DESIGN: Twenty-two young men performed 50-ECC of the elbow flexors using an isokinetic dynamometer. The subjects were randomly assigned to either the placebo or LTP group, and were each given a 4.5 mg/day placebo or LTP three-time on the exercise day and the day after...
November 20, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29189215/lateral-transperitoneal-adrenalectomy-versus-posterior-retroperitoneoscopic-adrenalectomy-for-benign-adrenal-gland-disease-randomized-controlled-trial-at-a-single-tertiary-medical-center
#11
Young Jun Chai, Hyeong Won Yu, Ra-Yeong Song, Su-Jin Kim, June Young Choi, Kyu Eun Lee
OBJECTIVE: The aim of this study was to compare the surgical outcomes of lateral transperitoneal adrenalectomy (LTA) and posterior retroperitoneoscopic adrenalectomy (PRA) for benign adrenal tumor. BACKGROUND: Although LTA is the standard treatment for benign adrenal gland tumor, PRA has recently gained popularity. Studies comparing the surgical outcomes of the 2 approaches have reported conflicting findings and thus it remains unclear which approach is superior...
November 20, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29184867/comorbidity-of-gynecological-and-non-gynecological-diseases-with-adenomyosis-and-endometriosis
#12
Eun Ji Choi, Seong Beom Cho, Sa Ra Lee, Young Mi Lim, Kyungah Jeong, Hye-Sung Moon, Hyewon Chung
Objective: Adenomyosis and endometriosis are relatively common gynecological diseases that exhibit many common features. This study identified gynecological and non-gynecological diseases that exhibited comorbidity with adenomyosis and endometriosis in Korean women. Methods: We used Health Insurance Review and Assessment data from 2009 to 2011 and searched for adenomyosis and endometriosis (coded as N80.1 and D25 in International Classification of Disease, 10th revision [ICD-10], respectively)...
November 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29179713/analysis-of-the-characteristics-of-cracked-teeth-and-evaluation-of-pulp-status-according-to-periodontal-probing-depth
#13
Sung-Eun Yang, A-Ra Jo, Hye-Jin Lee, Sin-Young Kim
BACKGROUND: The purpose of this study was to analyze the characteristics of cracked teeth and to evaluate pulp status according to periodontal probing depth (PPD). METHODS: A total of 182 cracked teeth were included. The location and type of the cracked teeth, age and gender of the patients, restoration type, pulp status, PPD, and radiographic findings were analyzed. RESULTS: Mandibular second molars (25.3%) were the most frequently involved teeth, followed by mandibular first molars (22...
November 28, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29175130/urinary-incontinence-is-strongly-associated-with-depression-in-middle-aged-and-older-korean-women-data-from-the-korean-longitudinal-study-of-ageing
#14
Young-Mee Lim, Sa Ra Lee, Eun Ji Choi, Kyungah Jeong, Hye Won Chung
OBJECTIVE: To investigate the relationship between urinary incontinence (UI) and depression in middle-aged and older Korean women. STUDY DESIGN: A total of 1116 participants diagnosed with UI among 7486 respondents were included in this study, using data from a well-established survey that investigated a nationally representative population: the Korean Longitudinal Study of Ageing (KLoSA). Computer-assisted personal interviewing was used to assess the status of UI and depression...
November 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29174850/association-between-pepsin-in-the-saliva-and-the-subjective-symptoms-in-patients-with-laryngopharyngeal-reflux
#15
Ah Ra Jung, Oh Eun Kwon, Jung Min Park, Sung Hwa Dong, Su Young Jung, Young Chan Lee, Young-Gyu Eun
OBJECTIVES: Our study was designed to further evaluate the relationships between the saliva pepsin level and the symptoms and quality of life of patients with laryngopharyngeal reflux (LPR). STUDY DESIGN: A prospective cohort study without controls. SETTING: Tertiary teaching hospital. SUBJECTS AND METHODS: We analyzed 50 patients diagnosed with LPR by 24-hour multichannel intraluminal impedance pH monitoring. All subjects were instructed to collect saliva samples upon waking in the morning...
November 24, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29172841/anti-inflammatory-effects-of-artemisia-scoparia-and-its-active-constituent-3-5-dicaffeoyl-epi-quinic-acid-against-activated-mast-cells
#16
Sun-Young Nam, Na-Ra Han, So-Young Rah, Youngwan Seo, Hyung-Min Kim, Hyun-Ja Jeong
OBJECTIVES: Artemisia scoparia Waldst. et Kit. (AS) has been used to treat inflammation, urticaria and hepatitis. However, the scientific studies of AS and its active compound for inflammatory reactions in activated human mast cell line, HMC-1 cells have not yet been elucidated. MATERIALS AND METHODS: Here, we isolated 3,5-dicaffeoyl-epi-quinic acid (DEQA) from AS butanol fraction. The anti-inflammatory effect of AS and its new active compound, DEQA was examined in HMC-1 cells by studying the following markers: phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-induced thymic stromal lymphopoietin (TSLP), tumor necrosis factor (TNF)-α, interleukin (IL)-1β and IL-6 secretion and mRNA expression by ELISA and RT-PCR, respectively...
November 27, 2017: Immunopharmacology and Immunotoxicology
https://www.readbyqxmd.com/read/29168791/administration-of-protocatechuic-acid-reduces-traumatic-brain-injury-induced-neuronal-death
#17
Sang Hwon Lee, Bo Young Choi, Song Hee Lee, A Ra Kho, Jeong Hyun Jeong, Dae Ki Hong, Sang Won Suh
Protocatechuic acid (PCA) was first purified from green tea and has shown numerous biological activities, including anti-apoptotic, anti-inflammatory, and anti-atherosclerotic effects. The effect of PCA on traumatic brain injury (TBI)-induced neuronal death has not previously been evaluated. TBI is defined as damage to the brain resulting from external mechanical force, such as rapid acceleration or deceleration, impact, blast waves, or penetration by a projectile. TBI causes neuronal death in the hippocampus and cerebral cortex...
November 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29159252/granulomatous-hepatitis-in-a-healthy-adult-after-bacillus-calmette-gu%C3%A3-rin-injection-into-a-plantar-wart
#18
Do Sik Moon, Woo Young Choi, Na-Ra Yoon, Dong-Min Kim
No abstract text is available yet for this article.
November 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/29147095/histochemical-characteristics-in-relation-to-meat-quality-traits-of-eight-major-muscles-from-hanwoo-steers
#19
Sung-Hyun Joo, Kyu-Won Lee, Young-Hwa Hwang, Seon-Tea Joo
The objective of this study was to determine the relationship between composition of muscle fiber types and meat quality traits of eight major muscles from Hanwoo steers. Longissimus lumborum (LL), psoas major (PM), semimembranosus (SM), semitendinosus (ST), gluteus medius (GM), triceps brachii (TB), rectus abdominis (RA) and superficialis flexor (SF) muscles were obtained from 9 Hanwoo steers and subjected to histochemical analysis. There were significant (p<0.05) differences in fiber number percentage (FNP) and fiber area percentage (FAP) of fiber types among these 8 major muscles...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/29142817/an-unusual-case-of-aortic-right-atrium-fistula-a-diagnostic-and-therapeutic-challenge
#20
Maria Chiara Todaro, Alessandro Aprile, Adriana Ravera, Gaetano Senatore
An aorta-to-right atrium (RA) fistula is an anomalous communication between the ascending or descending thoracic aorta and the RA. In this report, we describe a case of an idiopathic aortic root-to-RA fistula occasionally found during a coronary angiography performed in a young patient admitted for acute chest pain with evidence of multivessel coronary artery disease. The anatomical peculiarity of this fistulous communication is that it gave origin to collateral vessels furnishing the inferolateral wall of the left ventricle...
October 2017: Journal of Cardiovascular Echography
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