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abobotulinumtoxinA

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https://www.readbyqxmd.com/read/28431634/multicenter-observational-study-of-abobotulinumtoxina-neurotoxin-in-cervical-dystonia-the-anchor-cd-registry
#1
Richard M Trosch, Alberto J Espay, Daniel Truong, Ramon Gil, Carlos Singer, Peter A LeWitt, Mark F Lew, Michele Tagliati, Charles H Adler, Jack J Chen, Dominic Marchese, Cynthia L Comella
BACKGROUND: The ANCHOR-CD prospective observational registry study evaluated the effectiveness of abobotulinumtoxinA in adult idiopathic cervical dystonia (CD) in clinical practice. METHODS: Adults with CD were eligible. Treating physicians determined abobotulinumtoxinA dose and treatment interval. The primary endpoint was patient response rate (Toronto Western Spasmodic Torticollis Rating Scale [TWSTRS] score reduction≥25% and Patient Global Impression of Change [PGIC] score of +2 or +3 at Week 4 of Cycle 1)...
May 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28388721/safety-and-patient-satisfaction-of-abobotulinumtoxina-for-aesthetic-use-a-systematic-review
#2
Joel L Cohen, Nicolo Scuderi
HASH(0x43fb368)
May 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28388720/new-uses-of-abobotulinumtoxina-in-aesthetics
#3
Joel Schlessinger, Erin Gilbert, Joel L Cohen, Joely Kaufman
BotulinumtoxinA (BoNT-A) is now widely established for the main approved indication of reducing glabellar lines, and is also widely used off-label to improve the appearance of wrinkles and lines in other parts of the face. The number of aesthetic procedures continues to increase as the patient population becomes more diverse, in particular with increasing numbers of people of color and men. Further developments in treatment may continue to expand the audience for BoNT-A by making procedures more comfortable and by delivering a more natural, less static appearance...
May 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28388719/the-practical-use-of-abobotulinumtoxina-in-aesthetics
#4
Michael A C Kane, Gary Monheit
Botulinum toxin (BoNT) has been approved for aesthetic use since 2002. Since then, clinical studies and expert use have informed our understanding of how BoNT exerts its clinical effect and the practical use of this product across a number of aesthetic applications. This review discusses the clinical properties and characteristics of abobotulinumtoxinA, which patients are suitable for its use, and how it can be utilized to treat facial rhytides.
May 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28388718/abobotulinumtoxina-a-25-year-history
#5
Gary D Monheit, Andy Pickett
During the late 1960s and early 1970s, Alan Scott showed that intramuscular injections of botulinum toxin (BoNT) corrected nonaccommodative strabismus without resorting to surgery. The UK doctors who trained with Scott soon realized the significant potential offered by BoNT type A as a therapeutic option for several difficult-to-treat diseases. This led to a collaboration between these pioneering clinicians and the Centre for Applied Microbiology and Research at Porton Down, United Kingdom, and, in turn, to the development and commercialization of abobotulinumtoxinA as Dysport (Dystonia/Porton Down; Ipsen Biopharm Ltd...
May 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28388717/key-parameters-for-the-use-of-abobotulinumtoxina-in-aesthetics-onset-and-duration
#6
Mark Nestor, Glynis Ablon, Andy Pickett
Time to onset of response and duration of response are key measures of botulinum toxin efficacy that have a considerable influence on patient satisfaction with aesthetic treatment. However, there is no overall accepted definition of efficacy for aesthetic uses of botulinumtoxinA (BoNT-A). Mechanical methods of assessment do not lend themselves to clinical practice and clinicians rely instead on assessment scales such as the Frontalis Activity Measurement Standard, Frontalis Rating Scale, Wrinkle Severity Scale, and Subject Global Assessment Scale, but not all of these have been fully validated...
May 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28388716/introduction-to-the-supplement-a-review-of-abobotulinumtoxina-dysport
#7
Jeffrey S Dover
No abstract text is available yet for this article.
May 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28375973/incobotulinumtoxina-for-aesthetic-indications-a-systematic-review-of-prospective-comparative-trials
#8
Welf Prager, Diana Nogueira Teixeira, Phillip S Leventhal
BACKGROUND: IncobotulinumtoxinA is a botulinum toxin type A (BoNTA) indicated for temporary improvement in the appearance of upper facial lines with well-established efficacy and safety profiles. Whether incobotulinumtoxinA and other BoNTAs are equipotent is subject of debate. OBJECTIVE: To compare the efficacy of incobotulinumtoxinA and other BoNTAs for aesthetic applications. MATERIALS AND METHODS: PubMed and Embase were systematically searched for prospective clinical trials comparing incobotulinumtoxinA with onabotulinumtoxinA, abobotulinumtoxinA, or placebo for aesthetic applications...
April 3, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28367260/a-single-blind-split-face-randomized-pilot-study-comparing-the-effects-of-intradermal-and-intramuscular-injection-of-two-commercially-available-botulinum-toxin-a-formulas-to-reduce-signs-of-facial-aging
#9
Priya Sapra, Shantel Demay, Sheetal Sapra, Julie Khanna, Kelli Mraud, Jennifer Bonadonna
Objective: To examine the effectiveness of intradermal botulinum toxin type A injection in improving skin texture and midface lift while reducing pore size and sebum production, as well as investigate the differences in effectiveness between onabotulinumtoxinA and abobotulinumtoxinA using intradermal and intramuscular injection methods. Design: A 16-week, single-blind, split-face, randomized study. Each patient served as their own control, receiving onabotulinumtoxinA and abobotulinumtoxinA randomized to either the left or right side of the face...
February 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28263010/bilateral-analgesic-effects-of-abobotulinumtoxina-dysport-%C3%A2-following-unilateral-administration-in-the-rat
#10
C Favre-Guilmard, P-E Chabrier, M Kalinichev
BACKGROUND: In addition to inhibition of muscle and glandular hyperactivity, botulinum neurotoxin (BoNT) type A also interferes with pain processing. Previously, in a rat model of paclitaxel-induced polyneuropathy, abobotulinumtoxinA (aboBoNT-A) elicited analgesic effects not only in the injected paw, but also in the contralateral, non-injected paw. METHODS: Here, we assessed bilateral analgesic effects of unilateral aboBoNT-A in several chronic pain models in Sprague-Dawley rats...
May 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28200002/liquid-formulation-of-abobotulinumtoxina-exhibits-a-favorable-efficacy-and-safety-profile-in-moderate-to-severe-glabellar-lines-a-randomized-double-blind-placebo-and-active-comparator-controlled-trial
#11
Benjamin Ascher, Philippe Kestemont, Dominique Boineau, Isaac Bodokh, Annette Stein, Marc Heckmann, Markus Dendorfer, Tatjana Pavicic, Magali Volteau, Anissa Tse, Philippe Picaut, Berthold Rzany
No abstract text is available yet for this article.
February 14, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28068857/abobotulinumtoxina-dysport-%C3%A2-improves-function-according-to-goal-attainment-in-children-with-dynamic-equinus-due-to-cerebral-palsy
#12
Ann Tilton, Barry Russman, Resa Aydin, Umit Dincer, Raul G Escobar, Sehim Kutlay, Zbigniew Lipczyk, Juan Carlos Velez, Anne-Sophie Grandoulier, Anissa Tse, Philippe Picaut, Mauricio R Delgado
This secondary analysis of a large (n = 241), randomized, double-blind study evaluated the efficacy of 2 doses of abobotulinumtoxinA + standard of care (SOC) versus placebo + SOC in enabling children with dynamic equinus due to cerebral palsy to achieve their functional goals using Goal Attainment Scaling. Most parents/caregivers selected goals targeting aspects of gait improvement as most relevant. Mean (95% confidence interval) Goal Attainment Scaling T scores at week 4 were higher for both abobotulinumtoxinA groups versus placebo (treatment difference vs placebo: 10 U/kg/leg: 5...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/27852706/efficacy-of-two-injection-site-localisation-techniques-for-botulinum-toxin-injections-a-single-blind-crossover-randomised-trial-protocol-among-adults-with-hemiplegia-due-to-stroke
#13
Claire Morel, Isabelle Hauret, Nicolas Andant, Armand Bonnin, Bruno Pereira, Emmanuel Coudeyre
INTRODUCTION: Botulinum toxin injections are an effective treatment for limb spasticity following stroke. Different tracking techniques are used for this purpose: palpation, electrostimulation, electromyography and ultrasound. Yet very few studies have compared these different techniques, and none has successfully proved the superior efficacy of ultrasound-guided injections compared to another tracking method. The primary objective of our study was therefore to compare the efficacy of botulinum toxin injections depending on the tracking technique used: ultrasound versus electrostimulation...
November 15, 2016: BMJ Open
https://www.readbyqxmd.com/read/27810581/effect-of-botulinum-toxin-on-disabling-neuropathic-pain-a-case-presentation-suggesting-a-new-therapeutic-strategy
#14
Michelangelo Buonocore, Laura Demartini, Silvia Mandrini, Anna Dall'Angelo, Elena Dalla Toffola
This case presentation describes a 47-year-old woman who developed complex regional pain syndrome type II with severe neuropathic pain following iatrogenic transection of the tibial nerve at the ankle. The pain and disability progressively worsened over time, markedly impaired ambulation, and were not relieved despite various analgesic treatments. After injection of botulinum toxin (abobotulinumtoxinA, BoNT-A) in the leg muscles the tendons of which pass through the tarsal tunnel (together with the tibial nerve), her pain decreased and her walking capacity improved...
February 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673230/poster-485-safety-and-tolerability-of-abobotulinumtoxina-dysport-in-children-2-17-years-with-lower-limb-spasticity-due-to-cerebral-palsy-a-pooled-analysis-of-8-clinical-trials
#15
Dennis Matthews, George C Camba, Ignacio Pascual-Pascual, Ann H Tilton, Mark Gormley, Adnan Mahmood, Philippe Picaut, Daniel Snyder, Mauricio R Delgado
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673067/poster-313-relationship-between-abobotulinumtoxina-injections-into-shoulder-muscles-and-patient-centred-primary-goal-selection-and-achievement-sub-analyses-from-the-upper-limb-international-spasticity-ulis-ii-study
#16
Jorge Jacinto, Jovita Balcaitiene, Pascal Maisonobe, Klemens Fheodoroff, Stephen Ashford, Lynne Turner-Stokes
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673063/poster-308-improvement-of-spasticity-active-movements-and-active-function-after-repeated-injections-of-abobotulinumtoxina-dysport-in-adults-with-spastic-paresis-in-the-upper-limb-results-of-a-phase-iii-open-label-extension-study
#17
Christina Marciniak, Fatma Gul, Ziyad Ayyoub, David M Simpson, Heather W Walker, Michael Wimmer, Claire Vilain, Jean-Michel Graciès
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673052/poster-296-abobotulinumtoxina-injection-patterns-in-patients-with-cervical-dystonia-from-the-anchor-cd-registry-study
#18
Cynthia L Comella, George C Camba, Daniel Truong, Alberto J Espay, Daniel Snyder, Dominic Marchese, Richard Trosch
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673048/poster-292-improvement-of-spasticity-following-abobotulinumtoxina-dysport%C3%A2-injections-in-shoulder-muscles-in-hemiparetic-patients-with-upper-limb-spasticity-sub-analysis-of-a-prospective-long-term-open-label-study-with-single-and-repeated-injection-cycles
#19
Fatma Gul, Michael O'Dell, Robert Jech, Marta Banach, Claire Vilain, Anne-Sophie As Grandoulier, Jean-Michel Germain, Jean-Michel Graciès
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673046/poster-288-efficacy-and-safety-of-repeated-abobotulinumtoxina-injections-in-adults-with-lower-limb-spasticity
#20
Jean-Michel Gracies, Alberto Esquenazi, Allison Brashear, Steven R Edgley, Michael O'Dell, Peter Hedera, Bruce S Rubin, Philippe Picaut
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
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