keyword
https://read.qxmd.com/read/38652897/burn-pit-smoke-condensate-mediated-toxicity-in-human-airway-epithelial-cells
#1
JOURNAL ARTICLE
Arunava Ghosh, Alexis Payton, Samuel C Gallant, Keith L Rogers, Teresa Mascenik, Elise Hickman, Charlotte A Love, Kevin D Schichlein, Timothy R Smyth, Yong Ho Kim, Julia E Rager, M Ian Gilmour, Scott H Randell, Ilona Jaspers
Burn pits are a method of open-air waste management that was common during military operations in Iraq, Afghanistan, and other regions in Southwest Asia. Veterans returning from deployment have reported respiratory symptoms, potentially from exposure to burn pit smoke, yet comprehensive assessment of such exposure on pulmonary health is lacking. We have previously shown that exposure to condensates from burn pit smoke emissions causes inflammation and cytotoxicity in mice. In this study, we explored the effects of burn pit smoke condensates on human airway epithelial cells (HAECs) to understand their impact on cellular targets in the human lung...
April 23, 2024: Chemical Research in Toxicology
https://read.qxmd.com/read/38652713/frequency-complications-and-mortality-of-inhalation-injury-in-burn-patients-a-systematic-review-and-meta-analysis-protocol
#2
JOURNAL ARTICLE
Juliana Elvira Herdy Guerra Avila, Levy Aniceto Santana, Denise Rabelo Suzuki, Vinícius Zacarias Maldaner da Silva, Marcio Luís Duarte, Aline Mizusaki Imoto, Fábio Ferreira Amorim
INTRODUCTION: Burns are tissue traumas caused by energy transfer and occur with a variable inflammatory response. The consequences of burns represent a public health problem worldwide. Inhalation injury (II) is a severity factor when associated with burn, leading to a worse prognosis. Its treatment is complex and often involves invasive mechanical ventilation (IMV). The primary purpose of this study will be to assess the evidence regarding the frequency and mortality of II in burn patients...
2024: PloS One
https://read.qxmd.com/read/38652525/preferences-on-governance-models-for-mental-health-data-qualitative-study-with-young-people
#3
JOURNAL ARTICLE
Emma Grace Carey, Faith Oluwasemilore Adeyemi, Lakshmi Neelakantan, Blossom Fernandes, Mina Fazel, Tamsin Ford, Anne-Marie Burn
BACKGROUND: Improving access to mental health data to accelerate research and improve mental health outcomes is a potentially achievable goal given the substantial data that can now be collected from mobile devices. Smartphones can provide a useful mechanism for collecting mental health data from young people, especially as their use is relatively ubiquitous in high-resource settings such as the United Kingdom and they have a high capacity to collect active and passive data. This raises the interesting opportunity to establish a large bank of mental health data from young people that could be accessed by researchers worldwide, but it is important to clarify how to ensure that this is done in an appropriate manner aligned with the values of young people...
April 23, 2024: JMIR Formative Research
https://read.qxmd.com/read/38651709/a-woman-in-her-fifties-with-a-post-operative-infection-generalised-rash-and-organ-failure
#4
JOURNAL ARTICLE
Naima Borg Tahri, Berit Gravdehaug, Nazli Bahrami, Laurens Reitsma
BACKGROUND: Toxic shock syndrome (TSS) is a rare but potentially life-threatening disease caused by superantigen-producing Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. Staphylococcal TSS received special attention from 1978 to 1981, when an epidemic was observed associated with the use of hyper-absorbent tampons. Today the disease is rare and generally not related to menstruation, but can occur postpartum or in post-surgical wounds, intrauterine devices (IUDs), burns or other soft tissue injuries, mastitis or other focal infections...
April 23, 2024: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://read.qxmd.com/read/38648834/lumbar-spinal-stenosis-diagnosis-and-management
#5
JOURNAL ARTICLE
Charles W Webb, Kenneth Aguirre, Peter H Seidenberg
Lumbar spinal stenosis is a clinical syndrome that affects more than 200,000 people in the United States annually. It is a common cause of chronic insidious low back pain, especially in older patient populations (mean age = 64 years). Lumbar spinal stenosis is a degenerative condition of the spine leading to narrowing in the spaces around the neurovascular bundles and the classic symptom of low back pain that radiates to the buttocks and lower extremities bilaterally. It is typically a progressive waxing and waning process that may deteriorate over years...
April 2024: American Family Physician
https://read.qxmd.com/read/38648452/management-of-corneal-neovascularization-current-and-emerging-therapeutic-approaches
#6
JOURNAL ARTICLE
Duoduo Wu, Kai En Chan, Blanche Xiao Hong Lim, Dawn Ka-Ann Lim, Wendy Meihua Wong, Charmaine Chai, Ray Manotosh, Chris Hong Long Lim
Corneal neovascularization (CoNV) is a sight-threatening condition affecting an estimated 1.4 million people per year, and the incidence is expected to rise. It is a complication of corneal pathological diseases such as infective keratitis, chemical burn, corneal limbal stem cell deficiency, mechanical trauma, and immunological rejection after keratoplasties. CoNV occurs due to a disequilibrium in proangiogenic and antiangiogenic mediators, involving a complex system of molecular interactions. Treatment of CoNV is challenging, and no therapy thus far has been curative...
May 1, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38647997/is-egd-needed-in-all-patients-after-suicidal-or-exploratory-caustic-ingestions
#7
JOURNAL ARTICLE
Michael Levine, Yaron Finkelstein, William J Trautman, Dazhe Cao, Evan Schwarz, Ari Filip, Leanne Cook, Sameer Arbussattar Pathan, Cherie Obilom, Jim Liu, Joseph Yanta, Neta Cohen, Stephen H Thomas
BACKGROUND: Caustic ingestions are relatively uncommon, but remain a significant source of morbidity. Patients with caustic injury often undergo an urgent EGD, although it is not clear if an EGD is routinely needed in an asymptomatic patient. The study has two primary objectives; 1) to determine the utility of routine EGD in asymptomatic suicidal caustic ingestions; 2) to determine if asymptomatic unintentional acidic ingestions can be managed with observation alone, similar to basic ingestions...
April 22, 2024: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://read.qxmd.com/read/38643267/corneal-thermal-burn-injuries-during-long-duration-spaceflight-mechanisms-evaluation-and-management
#8
JOURNAL ARTICLE
Alex Suh, Joshua Ong, Ethan Waisberg, Andrew G Lee
No abstract text is available yet for this article.
April 20, 2024: Eye
https://read.qxmd.com/read/38642486/enhancing-soil-quality-and-yield-through-microbial-assisted-in-situ-residue-management-in-rice-rice-cropping-system-in-odisha-eastern-india
#9
JOURNAL ARTICLE
Periyasamy Panneerselvam, Ansuman Senapati, Debasis Mitra, Ankita Priyadarshini, Smriti Shadangi, Suchismita Behera, Upendra Kumar, Anjani Kumar, Mohammad Shahid, Sandeep Sharma, Rajendra Singh Garhwal, Indra Mani, Amaresh Kumar Nayak
Crop residue management has become more challenging with intensive agricultural operations. Zero tillage and crop residue returns, along with the enhancement of in-situ residue decomposition through microbial intervention, are essential measures for preserving and enhancing soil quality. To address this problem in view of stubble burning, field experiments were conducted in rice-rice (variety Swarna) cropping systems under lowland conditions, wherein the following different residue management practices were adopted viz...
April 19, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38640080/anesthesia-related-closed-claims-in-free-standing-ambulatory-surgery-centers
#10
JOURNAL ARTICLE
Marc Philip T Pimentel, Scott Chung, Jacqueline M Ross, Daniel Wright, Richard D Urman
BACKGROUND: As higher acuity procedures continue to move from hospital-based operating rooms (HORs) to free-standing ambulatory surgery centers (ASCs), concerns for patient safety remain high. We conducted a contemporary, descriptive analysis of anesthesia-related liability closed claims to understand risks to patient safety in the free-standing ASC setting, compared to HORs. METHODS: Free-standing ASC and HOR closed claims between 2015 and 2022 from The Doctors Company that involved an anesthesia provider responsible for the claim were included...
April 19, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38639968/hyperdiluted-botulinum-toxin-and-intense-pulsed-light-treatment-a-case-series-to-illustrate-a-novel-protocol-for-hypertrophic-scar-reduction
#11
JOURNAL ARTICLE
Mike D Clague, Greg Goodman, Cindy Taing, Lauren Stuart, Margo Orsatti, John Holbrook, John Delaney, Bridgina Mackay
Hypertrophic scars can have significant and far-reaching effects on patients that range from itching to creating difficulty with mobility, all of which can negatively impact the individual's quality of life. A recent study showed that many patients with recent scars report pain, burning, pruritus, erythema, in combination with psychological difficulties that impact bodily movement, choice of clothing, and participation in leisure activities. Botulinum toxin Type A (BoNTA) and intense pulsed light (IPL) have shown promise in treating such scars...
April 2024: Plast Aesthet Nurs (Phila)
https://read.qxmd.com/read/38638130/temporal-characterization-of-acute-pain-and-toxicity-kinetics-during-radiation-therapy-for-head-and-neck-cancer-a-retrospective-study
#12
JOURNAL ARTICLE
Vivian Salama, Sara Youssef, Tianlin Xu, Kareem A Wahid, Jaime Chen, Jillian Rigert, Anna Lee, Katherine A Hutcheson, Brandon Gunn, Jack Phan, Adam S Garden, Steven J Frank, William Morrison, Jay P Reddy, Michael T Spiotto, Mohamed A Naser, Cem Dede, Renjie He, Abdallah S R Mohamed, Lisanne V van Dijk, Ruitao Lin, Carlos J Roldan, David I Rosenthal, Clifton D Fuller, Amy C Moreno
OBJECTIVES: Pain during Radiation Therapy (RT) for oral cavity/oropharyngeal cancer (OC/OPC) is a clinical challenge due to its multifactorial etiology and variable management. The objective of this study was to define complex pain profiles through temporal characterization of pain descriptors, physiologic state, and RT-induced toxicities for pain trajectories understanding. MATERIALS AND METHODS: Using an electronic health record registry, 351 OC/OPC patients treated with RT from 2013 to 2021 were included...
September 2023: Oral Oncol Rep
https://read.qxmd.com/read/38633689/pain-and-wound-management-in-fungating-merkel-cell-carcinoma-within-a-palliative-setting-the-first-case-report-of-this-predicament
#13
Shaan Mohan, Ahmad Khan
Merkel cell carcinoma (MCC) is a rare type of skin cancer of the neuroendocrine Merkel mechanoreceptors. These cells are closely associated with nerve terminals and, given their proximity to cutaneous tissue, have the propensity to develop into deeply ulcerated, fungating malignancies. These friable wounds are easily irritated, and can cause significant pain for patients. We report a palliative case of severe, fungating MCC of the left scalp where the main contributor to the patient's illness burden is pain...
2024: Indian Journal of Palliative Care
https://read.qxmd.com/read/38633473/inhaled-volatile-anesthetics-in-the-intensive-care-unit
#14
REVIEW
Erin D Wieruszewski, Mariam ElSaban, Patrick M Wieruszewski, Nathan J Smischney
The discovery and utilization of volatile anesthetics has significantly transformed surgical practices since their inception in the mid-19th century. Recently, a paradigm shift is observed as volatile anesthetics extend beyond traditional confines of the operating theatres, finding diverse applications in intensive care settings. In the dynamic landscape of intensive care, volatile anesthetics emerge as a promising avenue for addressing complex sedation requirements, managing refractory lung pathologies including acute respiratory distress syndrome and status asthmaticus, conditions of high sedative requirements including burns, high opioid or alcohol use and neurological conditions such as status epilepticus...
March 9, 2024: World Journal of Critical Care Medicine
https://read.qxmd.com/read/38632298/the-efficacy-of-green-silica-nanoparticles-synthesized-from-rice-straw-in-the-management-of-callosobruchus-maculatus-col-bruchidae
#15
JOURNAL ARTICLE
Samar Sayed Ibrahim, Huda Hassan Elbehery, Ahmed Samy
Rice straw, a byproduct of harvesting rice, must be disposed of by farmers in a variety of ways, including burning, which is hazardous for the environment. To address this issue, the straw needs to be utilized and turned into valuable products. One such product is nano-silica (SNPs), which will be synthesized and investigated in our study as a safe alternative to chemical insecticides. Rice straw-derived SNPs were synthesized using the Sol-Gel method. The contact toxicity of SNPs on Callosobruchus maculatus, a major pest of cowpea seeds, has been assessed...
April 17, 2024: Scientific Reports
https://read.qxmd.com/read/38632014/severe-back-labor-pain-masks-a-scald-caused-by-shower-hydrotherapy-a-case-report
#16
P J Angle, V Ashok, G Liu, M Trenholm, J Montbriand
Shower hydrotherapy is generally considered benign during labor. We report a case of extensive scalds in a primigravida who used shower hydrotherapy to treat severe back labor pain from fetal malposition. Interestingly, her back pain was so severe that she felt no pain as her scald developed, describing the hot water from the showerhead as the only measure which "soothed" her pain. Her scald was diagnosed presumptively during assessment for epidural analgesia. The nature of her back labor pain, associated with occiput posterior fetal head position and her management are described...
March 28, 2024: International Journal of Obstetric Anesthesia
https://read.qxmd.com/read/38631147/high-risk-and-low-prevalence-diseases-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis
#17
REVIEW
Christiaan van Nispen, Brit Long, Alex Koyfman
INTRODUCTION: Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious conditions that carry a high rate of morbidity and mortality. OBJECTIVE: This review highlights the pearls and pitfalls of SJS/TEN, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence. DISCUSSION: SJS/TEN is a rare, delayed hypersensitivity reaction resulting in de-epithelialization of the skin and mucous membranes...
April 6, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38623992/navigating-scar-care-an-evaluation-of-scar-treatment-patient-education-materials
#18
JOURNAL ARTICLE
Artur Manasyan, Erin Ross, Brigette Cannata, Nicolas Malkoff, Elizabeth Flores, Haig A Yenikomshian, T Justin Gillenwater
While patient education materials (PEMs) across various specialties have been reported as being too difficult to read, the quality and understandability of PEMs related to scar management have not been assessed. In this study, we report the breadth of scar management interventions and readability of online PEMs authored by academic societies and university hospitals. Websites of academic medical societies and university hospitals with scar revision PEMs were assessed for relevance. PEM readability was assessed via Flesch Reading Ease, Flesch-Kincaid Grade Level, and Gunning-Fox Index scores...
April 16, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://read.qxmd.com/read/38622748/a-case-of-severe-benzalkonium-chloride-intoxication-in-a-cat
#19
JOURNAL ARTICLE
Silva Rubini, Roberto Rubini, Silvia Bertocchi, Silvia Zordan, Alice Magri, Filippo Barsi, Maria Sampieri, Carlo Alessandro Locatelli, Erika Baldini, Stefano Manfredini, Silvia Vertuani
BACKGROUND: Benzalkonium chloride (BAC) is a quaternary ammonium compound (QAC), that can be found in a wide variety of household products-from disinfectants to medicaments and home fragrances-but also professional products. In pets, cats have long been reported as more sensitive than dogs to QACs; in fact, signs of irritation such as oral ulcerations, stomatitis and pharyngitis can be observed after contact with concentrations of 2% or lower. In a review of 245 cases of BAC exposure in cats, reported by the Veterinary Poisons Information Service (United Kingdom) only 1...
April 15, 2024: Acta Veterinaria Scandinavica
https://read.qxmd.com/read/38622036/investigation-of-pre-discharge-learning-needs-and-affecting-factors-in-individuals-with-burns
#20
JOURNAL ARTICLE
Ahmet Özdemir, Ebru Yildiz Karadeniz, Emine Kaplan Serin
BACKGROUND: In discharge phase process, supporting patients to develop their own self-care strategies will increase their self-management skills and reduce complications and other health problems that may arise. AIM: The aim of the study is to examine the learning needs of individuals with burns regarding pre-discharge care and treatment and the factors affecting them. METHOD: Data from this cross-sectional study was collected with the "Descriptive Characteristics Form" and "Patient Learning Needs Scale (PLNS)"...
April 9, 2024: Journal of Tissue Viability
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