keyword
MENU ▼
Read by QxMD icon Read
search

Upper limb spasticity

keyword
https://www.readbyqxmd.com/read/29763510/trihexyphenidyl-for-dystonia-in-cerebral-palsy
#1
REVIEW
Adrienne R Harvey, Louise B Baker, Dinah Susan Reddihough, Adam Scheinberg, Katrina Williams
BACKGROUND: Cerebral palsy occurs in up to 2.1 of every 1000 live births and encompasses a range of motor problems and movement disorders. One commonly occurring movement disorder amongst those with cerebral palsy is dystonia: sustained or intermittent involuntary muscle spasms and contractions that cause twisting, repetitive movements and abnormal postures. The involuntary contractions are often very painful and distressing and cause significant limitations to activity and participation...
May 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29753889/onset-time-course-and-prediction-of-spasticity-after-stroke-or-traumatic-brain-injury
#2
REVIEW
K S Sunnerhagen, A Opheim, M Alt Murphy
OBJECTIVE: To describe spasticity from the onset of acquired brain injury, time course over the first year and factors associated with prediction of the development of spasticity METHODS: Recent relevant literature known to the authors, along with a complementary search yielding a total of 9 articles, represented the base for this scoping review. RESULTS: Spasticity can be seen in the first week after brain injury and is more common in the upper than lower extremity...
May 10, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29740633/effect-of-early-use-of-abobotulinumtoxina-after-stroke-on-spasticity-progression-protocol-for-a-randomised-controlled-pilot-study-in-adult-subjects-with-moderate-to-severe-upper-limb-spasticity-ontime-pilot
#3
Keng He Kong, Jovita Balcaitiene, Hugues Berard, Pascal Maisonobe, Khean Jin Goh, Witsanu Kumthornthip, Raymond L Rosales
Introduction: Approximately 15 million people suffer a stroke annually, up to 40% of which may develop spasticity, which can result in impaired limb function, pain and associated involuntary movements affecting motor control.Robust clinical data on spasticity progression, associated symptoms development and functional impairment is scarce. Additionally, maximal duration of muscle tone reduction following botulinum toxin type A (BoNT-A) injections remains undetermined. The ONTIME pilot study aims to explore these issues and evaluate whether abobotulinumtoxinA 500 U (Dysport® ; Ipsen) administered intramuscularly within 12 weeks following stroke delays the appearance or progression of symptomatic (disabling) upper limb spasticity (ULS)...
June 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29734901/the-role-of-selective-peripheral-neurectomy-in-the-treatment-of-upper-limb-spasticity
#4
Li Yenn Yong, Charis H L Wong, Mark Gaston, Wee Leon Lam
BACKGROUND: Management of upper limb spasticity remains challenging. Selective peripheral neurectomy (SPN) is a relatively recent intervention for cases refractory to medical therapy. The aim of this study was to conduct a systematic review looking at the efficacy and outcomes of SPN, in order to clarify the patient selection criteria and surgical technique. METHODS: A search of MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science Core Collection, Open Grey and CINAHL was conducted...
June 2018: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29701038/-dynamic-scalp-acupuncture-combined-with-pnf-therapy-for-upper-limb-motor-impairment-in-ischemic-stroke-spastic-hemiplegia
#5
Lili Qi, Zhenxiang Han, Yixin Zhou, Wenhua Chen, Lixi Chu, Jingjue Lu, Wenjie Xu, Honglin Wang, Zhibo Wang, Juan Ling
OBJECTIVE: On the basic therapy, to assess the clinical effects of dynamic scalp acupuncture, scalp acupuncture combined with proprioceptive neuromuscular facilitation (PNF) therapy and simple PNF therapy for upper limb motor impairment in ischemic post-stroke spastic hemiplegia. METHODS: A total of 90 cases were randomly assigned into a PNF group, a dynamic scalp acupuncture group and a scalp acupuncture group, 30 cases in each group. Basic therapy and PNF therapy were applied in the three groups...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29698489/altered-distribution-of-atg9a-and-accumulation-of-axonal-aggregates-in-neurons-from-a-mouse-model-of-ap-4-deficiency-syndrome
#6
Raffaella De Pace, Miguel Skirzewski, Markus Damme, Rafael Mattera, Jeffrey Mercurio, Arianne M Foster, Loreto Cuitino, Michal Jarnik, Victoria Hoffmann, H Douglas Morris, Tae-Un Han, Grazia M S Mancini, Andrés Buonanno, Juan S Bonifacino
The hereditary spastic paraplegias (HSP) are a clinically and genetically heterogeneous group of disorders characterized by progressive lower limb spasticity. Mutations in subunits of the heterotetrameric (ε-β4-μ4-σ4) adaptor protein 4 (AP-4) complex cause an autosomal recessive form of complicated HSP referred to as "AP-4 deficiency syndrome". In addition to lower limb spasticity, this syndrome features intellectual disability, microcephaly, seizures, thin corpus callosum and upper limb spasticity...
April 26, 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29669522/home-based-bimanual-training-based-on-motor-learning-principles-in-children-with-unilateral-cerebral-palsy-and-their-parents-the-coad-study-rationale-and-protocols
#7
Marlous Schnackers, Laura Beckers, Yvonne Janssen-Potten, Pauline Aarts, Eugène Rameckers, Jan van der Burg, Imelda de Groot, Rob Smeets, Sander Geurts, Bert Steenbergen
BACKGROUND: Home-based training is considered an important intervention in rehabilitation of children with unilateral cerebral palsy. Despite consensus on the value of home-based upper limb training, no evidence-based best practice exists. Promoting compliance of children to adhere to an intensive program while keeping parental stress levels low is an important challenge when designing home-based training programs. Incorporating implicit motor learning principles emerges to be a promising method to resolve this challenge...
April 18, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29664754/self-reported-upper-limb-functioning-of-pupils-with-cerebral-palsy-by-the-international-classification-of-functioning-disability-and-health
#8
Zoltán Lénárt, Eszter Szabó-Szemenyei, Adrienn A Tóth, Lajos Kullmann
International Classification of Functioning, Disability, and Health: Children and Youth Version has shown an increasing role in the assessment of children with cerebral palsy (CP), but just a few researchers use it for individuals' self-assessment. In this study, we present the self-assessment of functioning of students with CP and changes by the end of a school year. Thirty-seven pupils with spastic CP involving upper limbs, 24 pupils with typical development, and 20 pupils with speech and language disorders were studied by International Classification of Functioning, Disability, and Health core sets for CP...
April 16, 2018: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/29649706/quantitative-assessment-for-flexed-elbow-deformity-during-gait-following-botulinum-toxin-a-treatment
#9
Hiroki Tanikawa, Hitoshi Kagaya, Keisuke Inagaki, Yusuke Kotsuji, Keita Suzuki, Kenta Fujimura, Masahiko Mukaino, Satoshi Hirano, Eiichi Saitoh, Yoshikiyo Kanada
BACKGROUND: The effect of botulinum toxin A (BoNTA) injection on flexed-elbow deformity is usually evaluated using the Modified Ashworth Scale (MAS), but only with the muscle tone at rest. Some patients show the flexed-elbow deformity during gait despite low muscle tone at rest. OBJECTIVE: This study aimed to evaluate the effect of BoNTA injection on flexed-elbow deformity during gait using a three-dimensional motion analysis system. METHODS: Twenty stroke patients with spastic flexed-elbow deformity during gait received BoNTA injections into the upper limb muscles...
April 6, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29608917/time-dependent-bidirectional-anti-and-pro-spinal-hyper-reflexia-and-muscle-spasticity-effect-after-chronic-spinal-glycine-transporter-2-glyt2-oligonucleotide-induced-downregulation
#10
Kota Kamizato, Silvia Marsala, Michael Navarro, Manabu Kakinohana, Oleksandr Platoshyn, Tetsuya Yoshizumi, Nadezda Lukacova, Ed Wancewicz, Berit Powers, Curt Mazur, Martin Marsala
The loss of local spinal glycine-ergic tone has been postulated as one of the mechanisms contributing to the development of spinal injury-induced spasticity. In our present study using a model of spinal transection-induced muscle spasticity, we characterize the effect of spinally-targeted GlyT2 downregulation once initiated at chronic stages after induction of spasticity in rats. In animals with identified hyper-reflexia, the anti-spasticity effect was studied after intrathecal treatment with: i) glycine, ii) GlyT2 inhibitor (ALX 1393), and iii) GlyT2 antisense oligonucleotide (GlyT2-ASO)...
March 30, 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29587833/use-of-hybrid-assistive-limb-hal-%C3%A2-for-a-postoperative-patient-with-cerebral-palsy-a-case-report
#11
Yuki Mataki, Hiroshi Kamada, Hirotaka Mutsuzaki, Yukiyo Shimizu, Ryoko Takeuchi, Masafumi Mizukami, Kenichi Yoshikawa, Kazushi Takahashi, Mayumi Matsuda, Nobuaki Iwasaki, Hiroaki Kawamoto, Yasuyoshi Wadano, Yoshiyuki Sankai, Masashi Yamazaki
BACKGROUND: The Hybrid Assistive Limb (HAL® ) is an exoskeleton wearable robot suit that assists in voluntary control of knee and hip joint motion. There have been several studies on HAL intervention effects in stroke, spinal cord injury, and cerebral palsy. However, no study has investigated HAL intervention for patients with cerebral palsy after surgery. CASE PRESENTATION: We report a case of using HAL in a postoperative patient with cerebral palsy. A 15-year-old boy was diagnosed with spastic diplegia cerebral palsy Gross Motor Function Classification System level IV, with knee flection contracture, equinus foot, and paralysis of the right upper extremity with adduction contracture...
March 27, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29562552/physical-therapy-in-patients-with-disorders-of-consciousness-impact-on-spasticity-and-muscle-contracture
#12
A Thibaut, S Wannez, T Deltombe, G Martens, S Laureys, C Chatelle
BACKGROUND: Spasticity is a frequent complication after severe brain injury, which may prevent the rehabilitation process and worsen the patients' quality of life. OBJECTIVES: In this study, we investigated the correlation between spasticity, muscle contracture, and the frequency of physical therapy (PT) in subacute and chronic patients with disorders of consciousness (DOC). METHODS: 109 patients with subacute and chronic disorders of consciousness (Vegetative state/Unresponsive wakefulness syndrome - VS/UWS; minimally conscious state - MCS and patients who emerged from MCS - EMCS) were included in the study (39 female; mean age: 40±13...
2018: NeuroRehabilitation
https://www.readbyqxmd.com/read/29553309/effect-of-adding-upper-limb-rehabilitation-to-botulinum-toxin-a-on-upper-limb-activity-after-stroke-protocol-for-the-intense-trial
#13
Natasha A Lannin, Louise Ada, Coralie English, Julie Ratcliffe, Maria Crotty
Rationale Although clinical practice guidelines recommend that management of moderate to severe spasticity include the use of botulinum toxin-A in conjunction with therapy, there is currently no evidence to support the addition of therapy. Aims To determine the effect and cost-benefit of adding evidence-based movement training to botulinum toxin-A. Sample size estimate A total of 136 participants will be recruited in order to be able to detect a between-group difference of seven points on the Goal Attainment Scale T-score with 80% power at a two-tailed significance level of 0...
January 1, 2018: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29544888/clinical-phenotype-of-hereditary-spastic-paraplegia-due-to-kif1c-gene-mutations-across-life-span
#14
Didem Yücel-Yılmaz, Emrah Yücesan, Dilek Yalnızoğlu, Kader Karlı Oğuz, Mahmut Şamil Sağıroğlu, Uğur Özbek, Esra Serdaroğlu, Başar Bilgiç, Sevim Erdem, Sibel Aylin Uğur İşeri, Haşmet Hanağası, Hakan Gürvit, Rıza Köksal Özgül, Ali Dursun
Hereditary spastic paraplegias (HSPs) are a group of genetic disorders resulting in pyramidal tract impairment, predominantly in lower limbs. KIF1C gene has recently been identified as one of the genetic causes of HSP and associated with pure or complicated HSP. We present three patients with complicated HSP from two unrelated families, who had early onset progressive cerebellar signs and developed pyramidal tract signs during follow-up. Whole exome sequencing in these patients followed by segregation analysis identified novel truncating KIF1C mutations (c...
March 12, 2018: Brain & Development
https://www.readbyqxmd.com/read/29543678/clinical-notes-on-chiari-malformation
#15
Rajani Singh, Rajnish Arora, Raj Kumar
Chiari malformations (CMs) are variant structural setup of cerebellum and brain stem at the craniovertebral junction. Normally the cerebellum and parts of the brain stem lie above the foramen magnum. When the part of the cerebellum and/or brainstem protrudes into the upper spinal canal through foramen magnum, it is defined as CM. Chiari malformations may develop when part of the skull is smaller than normal or misshapen, due to which the cerebellum herniates into spinal canal through foramen magnum. This compresses the cerebellum and brainstem affecting functions controlled by these parts and blocks the flow of cerebrospinal fluid that surrounds and cushions the brain and spinal cord...
March 14, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29492272/mirror-therapy-for-an-adult-with-central-post-stroke-pain-a-case-report
#16
Davide Corbetta, Elisabetta Sarasso, Federica Agosta, Massimo Filippi, Roberto Gatti
Background: Treatment of central post-stroke pain (CPSP) after a thalamic-capsular stroke is generally based on pharmacological approach as it is low responsive to physiotherapy. In this case report, the use of mirror therapy (MT) for the reduction of CPSP in a subject after a stroke involving thalamus is presented. Case presentation: Five years after a right lenticular-capsular thalamic stroke, despite a good recovery of voluntary movement that guaranteed independence in daily life activities, a 50-year-old woman presented with mild weakness and spasticity, an important sensory loss and a burning pain in the left upper limb...
2018: Archives of physiotherapy
https://www.readbyqxmd.com/read/29490539/activity-gains-after-upper-limb-surgery-for-spasticity-in-patients-with-spinal-cord-injury
#17
Johanna Wangdell, Carina Reinholdt, Jan Fridén
Spasticity is a common and increasingly prevalent secondary complication of spinal cord injury. The aim of the study was to evaluate patient-experienced gains in prioritized activities after surgery to reduce the effects of spasticity in upper limbs in tetraplegia. The study includes evaluation of 30 operations for 27 patients performed on hypertonic tetraplegic hands during 2007-2015 using the Canadian Occupational Performance Measure. Activity performance increased at both 6 months and 12 months by a mean of 3...
January 1, 2018: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29482558/spasticity-assessment-based-on-the-hilbert-huang-transform-marginal-spectrum-entropy-and-the-root-mean-square-of-surface-electromyography-signals-a-preliminary-study
#18
Baohua Hu, Xiufeng Zhang, Jingsong Mu, Ming Wu, Yong Wang
BACKGROUND: Most of the objective and quantitative methods proposed for spasticity measurement are not suitable for clinical application, and methods for surface electromyography (sEMG) signal processing are mainly limited to the time-domain. This study aims to quantify muscle activity in the time-frequency domain, and develop a practical clinical method for the objective and reliable evaluation of the spasticity based on the Hilbert-Huang transform marginal spectrum entropy (HMSEN) and the root mean square (RMS) of sEMG signals...
February 27, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29473352/-effects-of-pricking-and-cupping-combined-with-rehabilitation-training-on-elbow-flexion-spasticity-of-upper-limb-after-stroke-and-its-iemg-value
#19
Zhiqiang Huang, Ning Zhao, Zhaoyuan Su, Jiafu Su, Qiang Wu
OBJECTIVE: Based on rehabilitation training, to observe the clinical effect difference between pricking combined with cupping and western medication for elbow flexion spasticity of upper limb of stroke patients. METHODS: Sixty patients were randomly assigned by SPSS software random number generator into a comprehension group and a western medication group, 30 cases in each one. Rehabilitation was used in the two groups. Pricking and cupping were applied at the affected abdominal center of biceps brachii muscle on Tuesday and Friday continuously for 4 weeks in the comprehensive group...
February 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29466440/predictors-of-activities-of-daily-living-outcomes-after-upper-limb-robot-assisted-therapy-in-subacute-stroke-patients
#20
Marco Franceschini, Michela Goffredo, Sanaz Pournajaf, Stefano Paravati, Maurizio Agosti, Francesco De Pisi, Daniele Galafate, Federico Posteraro
BACKGROUND: Upper limb recovery is one of the main goals of post-stroke rehabilitation due to its importance for autonomy in Activities of Daily Living (ADL). Although the efficacy of upper limb Robot-assisted Therapy (RT) is well established in literature, the impact of the initial status of the patient on the effects of RT is still understudied. This paper aims to identify whether demographic, clinical and motor characteristics of stroke patients may influence the ability to independently perform ADL after RT...
2018: PloS One
keyword
keyword
9453
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"