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Upper limb spasticity

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https://www.readbyqxmd.com/read/29126361/a-survey-of-the-current-practice-of-intramuscular-botulinum-toxin-injections-for-hemiplegic-shoulder-pain-in-the-uk
#1
Richard J Holmes, Louise A Connell
PURPOSE: To describe the current UK practice for the use of intramuscular Botulinum Toxin type A injections to treat hemiplegic shoulder pain. METHOD: A UK-based cross-sectional study using an online survey. Participants (n = 68) were medical and non-medical practitioners recruited via the membership of the British Society for Rehabilitation Medicine and the British Neurotoxin Network. Data was analysed using descriptive statistics and content analysis. RESULTS: The majority of respondents would consider Botulinum Toxin type A for hemiplegic shoulder pain (86...
November 10, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29123918/whole-genome-sequencing-identifies-a-novel-homozygous-exon-deletion-in-the-nt5c2-gene-in-a-family-with-intellectual-disability-and-spastic-paraplegia
#2
Hossein Darvish, Luis J Azcona, Abbas Tafakhori, Mona Ahmadi, Azadeh Ahmadifard, Coro Paisán-Ruiz
Hereditary spastic paraplegias are a rare group of clinically and genetically heterogeneous neurodegenerative diseases, with upper motor neuron degeneration and progressive lower limb spasticity as their main phenotypic features. Despite that 76 distinct loci have been reported and some casual genes identified, most of the underlying causes still remain unidentified. Moreover, a wide range of clinical manifestations is present in most hereditary spastic paraplegias subtypes, adding further complexity to their differential clinical diagnoses...
2017: NPJ Genomic Medicine
https://www.readbyqxmd.com/read/29116382/selective-dorsal-rhizotomy-for-the-treatment-of-severe-spastic-cerebral-palsy-efficacy-and-therapeutic-durability-in-gmfcs-grade-iv-and-v-children
#3
Daniel D'Aquino, Ahmad A Moussa, Amr Ammar, Harshal Ingale, Michael Vloeberghs
BACKGROUND: Selective dorsal rhizotomy (SDR) has been established as an effective surgical treatment for spastic diplegia. The applicability of SDR to the full spectrum of spastic cerebral palsy and the durability of its therapeutic effects remain under investigation. There are currently limited data in the literature regarding efficacy and outcomes following SDR in Gross Motor Function Classification System (GMFCS) IV and V patients. Intrathecal baclofen has traditionally been the surgical treatment of choice for these patients...
November 7, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29094043/hand-passive-mobilization-performed-with-robotic-assistance-acute-effects-on-upper-limb-perfusion-and-spasticity-in-stroke-survivors
#4
Massimiliano Gobbo, Paolo Gaffurini, Laura Vacchi, Sara Lazzarini, Jorge Villafane, Claudio Orizio, Stefano Negrini, Luciano Bissolotti
This single arm pre-post study aimed at evaluating the acute effects induced by a single session of robot-assisted passive hand mobilization on local perfusion and upper limb (UL) function in poststroke hemiparetic participants. Twenty-three patients with subacute or chronic stroke received 20 min passive mobilization of the paretic hand with robotic assistance. Near-infrared spectroscopy (NIRS) was used to detect changes in forearm tissue perfusion. Muscle tone of the paretic UL was assessed by the Modified Ashworth Scale (MAS)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29075344/efficacy-of-cerebrolysin-in-the-reduction-of-spasticity-during-stroke-rehabilitation
#5
R M Martinez
AIM: This study assessed the efficacy of Cerebrolysin on post-stroke spasticity, motor recovery, and global functions in an outpatient rehabilitation setting. METHODS: In this retrospective comparison study, Cerebrolysin was administered at a daily dosage of 10 ml for over 30 days as an intramuscular injection. Control patients did not receive Cerebrolysin. All the patients participated in a standardized physical and occupational rehabilitation therapy for one month at least two times per week...
July 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/29051729/negative-influence-of-motor-impairments-on-upper-limb-movement-patterns-in-children-with-unilateral-cerebral-palsy-a-statistical-parametric-mapping-study
#6
Cristina Simon-Martinez, Ellen Jaspers, Lisa Mailleux, Kaat Desloovere, Jos Vanrenterghem, Els Ortibus, Guy Molenaers, Hilde Feys, Katrijn Klingels
Upper limb three-dimensional movement analysis (UL-3DMA) offers a reliable and valid tool to evaluate movement patterns in children with unilateral cerebral palsy (uCP). However, it remains unknown to what extent the underlying motor impairments explain deviant movement patterns. Such understanding is key to develop efficient rehabilitation programs. Although UL-3DMA has been shown to be a useful tool to assess movement patterns, it results in a multitude of data, challenging the clinical interpretation and consequently its implementation...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29041999/electrodiagnostic-and-nerve-ultrasonographic-features-in-upper-limb-spasticity-an-observational-study
#7
A Picelli, S Tamburin, G Berto, E Chemello, Marialuisa Gandolfi, Leopold Saltuari, Andreas Waldner, Nicola Smania
To better understand the effects of spasticity on peripheral nerves, we evaluated the electrodiagnostic and nerve ultrasonographic features of the median and ulnar nerves in adults with upper limb spasticity. Twenty chronic stroke patients with spastic hemiparesis underwent nerve conduction study and nerve ultrasonography of the median and ulnar nerves at both upper limbs. Affected versus unaffected upper limb comparisons showed significant differences in the median and ulnar nerve distal motor latencies, compound muscle action potentials and F-wave minimal latencies...
July 2017: Functional Neurology
https://www.readbyqxmd.com/read/29033227/spasticity-and-hyperselective-neurectomy-in-the-upper-limb
#8
M Gras, C Leclercq
Spasticity is a complex pathology, both in terms of assessment and treatment. This article focuses on the clinical examination (objective, capacity, performance and function), which is key for choosing a treatment and can be helped by botulinum toxin injections. The treatment involves physical therapy, occupational therapy, medications and surgery. Neurectomy has been used in the upper limb since 1912 and is one of the therapeutic options for spasticity. This treatment is usually reserved for nonfunctional hands...
October 12, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28973961/adapting-tai-chi-for-upper-limb-rehabilitation-post-stroke-a-feasibility-study
#9
Shujuan Pan, Dahlia Kairy, Hélène Corriveau, Michel Tousignant
Background: Tai chi (TC) has been reported as being beneficial for improving balance post stroke, yet its utility in upper limb rehabilitation remains unknown. Methods: Twelve chronic stroke survivors with persistent paresis of an upper limb underwent 60 minutes of adapted TC twice a week for eight weeks, with a 4-week follow up. A 10-min TC home program was recommended for the days without sessions. TC level of performance, attendance to the sessions, duration of self-practice at home, and adapted TC movements used were recorded...
September 30, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28973024/is-two-better-than-one-muscle-vibration-plus-robotic-rehabilitation-to-improve-upper-limb-spasticity-and-function-a-pilot-randomized-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Rocco Salvatore Calabrò, Antonino Naro, Margherita Russo, Demetrio Milardi, Antonino Leo, Serena Filoni, Antonia Trinchera, Placido Bramanti
Even though robotic rehabilitation is very useful to improve motor function, there is no conclusive evidence on its role in reducing post-stroke spasticity. Focal muscle vibration (MV) is instead very useful to reduce segmental spasticity, with a consequent positive effect on motor function. Therefore, it could be possible to strengthen the effects of robotic rehabilitation by coupling MV. To this end, we designed a pilot randomized controlled trial (Clinical Trial NCT03110718) that included twenty patients suffering from unilateral post-stroke upper limb spasticity...
2017: PloS One
https://www.readbyqxmd.com/read/28971038/effective-site-for-the-application-of-extracorporeal-shock-wave-therapy-on-spasticity-in-chronic-stroke-muscle-belly-or-myotendinous-junction
#11
Sang Ho Yoon, Min Kyung Shin, Eun Jung Choi, Hyo Jung Kang
OBJECTIVE: To compare the effect of extracorporeal shock-wave therapy (ESWT) applied at the muscle belly and myotendinous junction on spasticity in the upper and lower limbs of chronic stroke patients. METHODS: Of the 151 patients, a total of 80 patients with stroke-induced spasticity on the elbow flexor and 44 patients on the knee flexor were enrolled for a prospective, randomized clinical trial. The patients were divided into control, muscle belly, and myotendinous junction groups, and a total of three ESWT sessions (0...
August 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28957737/interplay-of-upper-and-lower-motor-neuron-degeneration-in-amyotrophic-lateral-sclerosis
#12
Mamede de Carvalho, Artiom Poliakov, Cristiano Tavares, Michael Swash
OBJECTIVE: We studied motor unit recruitment to test a new method to identify motor unit firing rate (FR) variability. METHODS: We studied 68 ALS patients, with and without upper neuron signs (UMN) in lower limbs, 24 patients with primary lateral sclerosis (PLS), 13 patients with spinal cord lesion and 39 normal subjects. All recordings were made from tibialis anterior muscles of normal strength. Subjects performed a very slight contraction in order to activate 2 motor units in each recording...
September 19, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28947166/upper-limb-isokinetic-strengthening-versus-passive-mobilization-in-patients-with-chronic-stroke-a-randomized-controlled-trial
#13
F Coroian, C Jourdan, K Bakhti, C Palayer, A Jaussent, M C Picot, D Mottet, M Julia, H Y Bonnin, I Laffont
OBJECTIVE: To assess the benefit of isokinetic strengthening (IS) of the upper limb (UL) in chronic stroke patients, compared to passive mobilization. DESIGN: Randomized blinded assessor controlled trial. SETTING: PRM departments of two University Hospitals. PARTICIPANTS: 20 patients with incomplete hemiplegia, 16 men, mean age 64 years, median time since stroke 32 months. INTERVENTION: A 6-week comprehensive rehabilitation program, 3 days/week, three sessions/day...
September 22, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28919314/24-hour-alberta-stroke-program-early-ct-score-assessment-in-post-stroke-spasticity-development-in-patients-with-a-first-documented-anterior-circulation-ischemic-stroke
#14
Ondrej Volny, Maria Justanova, Petra Cimflova, Linda Kasickova, Ivana Svobodova, Jan Muzik, Martin Bares
BACKGROUND: Neuroanatomic substrates responsible for development of post-stroke spasticity are still poorly understood. The study is focused on identification of brain regions within the territory of the middle cerebral artery associated with spasticity development. METHODS: This is a single-center prospective cohort study of first documented anterior circulation ischemic strokes with a neurologic deficit lasting >7 days (from March 2014 to September 2016, all patients are involved in a registry)...
September 14, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28917371/cannabinoids-for-spasticity-due-to-multiple-sclerosis-or-paraplegia-a-systematic-review-and-meta-analysis-of-randomized-clinical-trials
#15
REVIEW
Victoria P da Rovare, Gabriel P A Magalhães, Guilherme D A Jardini, Matheus L Beraldo, Mariel O Gameiro, Arnav Agarwal, Gustavo José Luvizutto, Lucas Paula-Ramos, Samira Esteves Afonso Camargo, Luciane Dias de Oliveira, Rodrigo Bazan, Regina El Dib
OBJECTIVES: Spasticity remains highly prevalent in patients with spinal cord injury and multiple sclerosis. To summarize the effects of cannabinoids compared with usual care, placebo for spasticity due to multiple sclerosis (MS) or paraplegia. METHODS: Searches of MEDLINE, EMBASE, CENTRAL and LILACS to March 2017 were performed to identify randomized controlled trials. The primary outcomes were spasticity and spasm frequency. The criteria were any patient with MS and spasticity affecting upper or lower limbs or both, and that had a confirmed diagnosis of MS based on validated criteria, or however defined by the authors of the included studies...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28888345/erratum-to-contralesional-cathodal-versus-dual-transcranial-direct-current-stimulation-for-decreasing-upper-limb-spasticity-in-chronic-stroke-individuals-a-clinical-and-neurophysiological-study
#16
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28870592/computer-based-assessment-of-upper-limb-incoordination-in-autosomal-recessive-spastic-ataxia-of-charlevoix-saguenay-patients-a-pilot-study
#17
Hung Tien Bui, Olivier Audet, Jean Mathieu, Cynthia Gagnon, Mario Leone
Ataxia refers to a group of neurological disorders characterized by a lack of coordination during voluntary movements. One of the most commonly used tests to assess upper-limb coordination is the Archimedes spiral test. The purpose of this research is to present an innovative computer-based Archimedes spiral test that can accurately assess coordination. Forty nine individuals (age: 25.2±7.1years) were recruited including thirteen patients diagnosed with Autosomal Recessive Spastic Ataxia of Charlevoix/Saguenay (ARSACS)...
September 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28870058/technologically-advanced-assessment-of-upper-limb-spasticity-a-pilot-study
#18
Federico Posteraro, Simona Crea, Stefano Mazzoleni, Mihai Berteanu, Ileana Ciobanu, Nicola Vitiello, Marco Cempini, Sabata Gervasio, Natalie Mrachacz-Kersting
BACKGROUND: Spasticity is a muscle disorder associated with upper motor neuron syndrome occurring in neurological disorders, such as stroke, multiple sclerosis, spinal cord injury and others. It influences the patient's rehabilitation, interfering with function, limiting independence, causing pain and producing secondary impairments, such as contractures or other complications. Due to the heterogeneity of clinical signs of spasticity, there is no agreement on the most appropriate assessment and measurement modality for the evaluation of treatment outcomes...
September 4, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28813915/vibrofocus-design-of-a-focal-vibro-tactile-robotic-assistive-system-for-spasticity-rehabilitation
#19
Tijana Jevtic Vojinovic, Aleksandar Zivanovic, Tom Carlson, Rui C V Loureiro
The main focus of spasticity treatment is to alleviate pain, improve function and reduce risk of additional complications. In this paper the design of a robotic system with enhanced focal vibro-tactile stimulation for the treatment of spasticity in the upper limbs is presented. Building on emerging evidence on the use of vibrations in the treatment of spasticity, we propose a new integrated approach. Our design combines the use of vibro-tactile stimulation of the high tone muscle with robotic movement assistance to augment rehabilitation outcomes in patients with spasticity in the upper limbs...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813912/transverse-forces-versus-modified-ashworth-scale-for-upper-limb-flexion-extension-in-para-sagittal-plane
#20
Nitin Seth, Denise Johnson, Hussein A Abdullah
Spasticity is a common impairment following an upper motor neuron lesion in conditions such as stroke and brain injury. A clinical issue is how to best quantify and measure spasticity. Recently, research has been performed to develop new methods of spasticity quantification using various systems. This paper follows up on previous work taking a closer look at the role of transversal forces obtained via rehabilitation robot for motions in the para-sagittal plane. Results from 45 healthy individuals and 40 individuals with acquired brain injury demonstrate that although the passive upper motions are vertical, horizontal forces into and away from the individual's body demonstrate a relationship with the Modified Ashworth Scale...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
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