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Benign biliary stricture

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https://www.readbyqxmd.com/read/28815030/a-combined-bile-and-urine-proteomic-test-for-cholangiocarcinoma-diagnosis-in-patients-with-biliary-strictures-of-unknown-origin
#1
Torsten Voigtländer, Jochen Metzger, Bastian Schönemeier, Mark Jäger, Harald Mischak, Michael P Manns, Tim O Lankisch
BACKGROUND: Detection of cholangiocarcinoma (CC) remains a diagnostic challenge particularly in patients with primary sclerosing cholangitis (PSC). We recently established diagnostic peptide marker models in bile and urine to detect CC. Our aim was to combine both models to reach a higher diagnostic accuracy of CC diagnosis. METHODS: Bile (BPA) and urine (UPA) proteome analysis by capillary electrophoresis mass spectrometry was performed in a case-control phase II study on 87 patients (36 CC including 13 with CC on top of PSC, 33 PSC and 18 other benign disorders)...
August 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28776138/a-new-fully-covered-self-expandable-metal-stent-for-the-treatment-of-postsurgical-benign-biliary-strictures
#2
Jun Wu, Dong-Xun Zhou, Tian-Tian Wang, Dao-Jian Gao, Bing Hu
BACKGROUND: Endotherapy with plastic stent (PS) placement is the main modality for treating benign biliary strictures (BBSs). Fully covered self-expandable metal stents (FCSEMSs) are being increasingly used for BBS management, with high stricture resolution. However, traditional metal tents are associated with high migration, causing treatment failure. METHODS: We investigated the efficacy and safety of a new FCSEMS for postsurgical BBS treatment and compared these parameters between the FCSEMS and PS treatment through retrospective analysis...
August 3, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28738976/proposal-of-a-diagnostic-algorithm-for-intraductal-ultrasonography-to-distinguish-between-benign-and-malignant-biliary-strictures
#3
Yao-Sheng Wang, Chiao-Hsiung Chuang, Jhong-Han Wu, Chiung-Yu Chen
To reexamine the recognizability of intraductal ultrasonography (IDUS) findings from an imaging database and propose a novel algorithm for clinical application. IDUS images of 102 patients who had undergone IDUS examinations for indeterminate causes of common bile duct dilation were independently reviewed by two endoscopists. The strength of the inter-rater agreement between the endoscopists was analyzed using Cohen's kappa (κ). An algorithm was implemented by arranging the IDUS characteristics according to their recognizability...
July 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28725941/endoscopic-stents-for-the-biliary-tree-and-pancreas
#4
REVIEW
Rajesh Krishnamoorthi, Mahendran Jayaraj, Richard Kozarek
OPINION STATEMENT: PURPOSE OF REVIEW: To review the recently published literature on biliary and pancreatic stents. RECENT FINDINGS: Covered self-expanding metal stents (SEMS) are increasingly being used in the endoscopic management of benign biliary strictures. Given the costs associated with SEMS, plastic stents are still the most commonly used stents. In this setting, SEMS are preferred over plastic stents for palliation of malignant biliary strictures due to superior patency and have a role in preoperative management of malignant biliary strictures...
July 20, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28706774/are-dominant-strictures-in-primary-sclerosing-cholangitis-a-risk-factor-for-cholangiocarcinoma
#5
REVIEW
Roger W Chapman, Kate D Williamson
PURPOSE OF REVIEW: Cholangiocarcinoma is a devastating, unpredictable complication of large duct primary sclerosing cholangitis (PSC), which occurs in 5-15% of patients. The aim of this review is to discuss whether dominant strictures (DS) occurring in the larger bile ducts in PSC are a risk factor for the development of cholangiocarcinoma. RECENT FINDINGS: The development of DS is related to specific genetic polymorphisms affecting the innate immune system and the microbiome...
2017: Current Hepatology Reports
https://www.readbyqxmd.com/read/28664637/author-s-response-endoscopic-biodegradable-biliary-stents-in-the-treatment-of-benign-biliary-strictures-the-first-report-in-clinical-use-in-patients-antti-siiki-irina-rinta-kiikka-and-johanna-laukkarinen
#6
Antti Siiki, Irina Rinta-Kiikka, Johanna Laukkarinen
We appreciate the comments of Dr. Koksal and co-workers on our recent article. In brief, we reported on two first patients with benign biliary strictures treated with self-expanding poly-dioxanone biodegradable biliary stents (BDBS) inserted in endoscopic retrograde cholangiography (ERC). The authors underline that BDBS may cause epithelial hyperplasia in the bile duct similarly to oesophageal use. This article is protected by copyright. All rights reserved.
June 30, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28645679/percutaneous-management-of-benign-biliary-disorders-in-children
#7
G Kahriman, N Ozcan, S B Gorkem
PURPOSE: The goal of this study was to analyze the outcomes of percutaneous transhepatic management of benign biliary disorders in pediatric patients. MATERIALS AND METHODS: This study included 11 pediatric patients who underwent percutaneous transhepatic biliary interventional procedures between September 2007 and December 2016. There were 3 males and 8 females with a mean age of 9.6±5.4 (SD)years (range: 2-17years). Technical details, complications and outcome of the procedures were evaluated...
June 20, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28643071/forgotten-biliary-stents-ignorance-is-not-bliss
#8
Saket Kumar, Abhijit Chandra, Rugved Kulkarni, Ajeet Pratap Maurya, Vishal Gupta
BACKGROUND: Endoscopic biliary stenting is a common procedure in routine gastroenterology practice. Plastic stents are the most common type of stents used and are indicated mainly for short-term biliary drainage. Prolonged indwelling plastic stents can result in disastrous complications. METHODS: We conducted a retrospective analysis of patients who presented with complications of forgotten biliary stents in a tertiary care hospital during January 2010 to October 2016...
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28636091/biodegradable-stents-in-the-treatment-of-benign-biliary-strictures-does-one-size-fit-all
#9
Aydin Seref Koksal, Ahmet Tarik Eminler, Erkan Parlak
We read the article entitled 'Endoscopic biodegradable biliary stents in the treatment of benign biliary strictures: First report on clinical use in patients' by Siiki et al with great interest (1). The authors successfully treated two patients with benign biliary strictures, possibly due to choledocholithiasis, with endoscopic insertion of polydioxanone biodegradable biliary stents. They reported that the treatment was uneventful and the stents were completely dissolved between 3 and 6 months without leaving a sequela in the bile ducts...
June 21, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28597680/fishbone-impaction-in-the-colon
#10
Armando Peixoto, Marco Silva, Branca Órfão, Guilherme Macedo
Postoperative benign biliary stricture in the anastomotic site is one of the most common complications of biliary-enteric anastomosis, with a rate of 6.87% after 2-13 years of follow-up. If untreated, biliary strictures can induce other complications such as recurrent cholangitis, intrahepatic stones, pancreatitis and secondary biliary cirrhosis. We report our experience with extracorporeal shock wave lithotripsy (ESWL) in a patient with a massive symptomatic stone proximal to an anastomotic biliary stricture...
June 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28597679/successful-extracorporeal-shock-wave-lithotripsy-eswl-treatment-of-a-symptomatic-massive-biliary-stone-proximal-to-an-anastomotic-biliary-stricture
#11
Rosangela Muratori, Daniele Mandolesi, Maria Cristina Galaverni, Francesco Azzaroli
Postoperative benign biliary stricture in the anastomotic site is one of the most common complications of biliary-enteric anastomosis, with a rate of 6.87% after 2-13 years of follow-up. If untreated, biliary strictures can induce other complications such as recurrent cholangitis, intrahepatic stones, pancreatitis and secondary biliary cirrhosis. We report our experience with extracorporeal shock wave lithotripsy (ESWL) in a patient with a massive symptomatic stone proximal to an anastomotic biliary stricture...
June 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28561199/efficacy-of-self-expandable-metal-stents-in-management-of-benign-biliary-strictures-and-comparison-with-multiple-plastic-stents-a-meta-analysis
#12
Muhammad Ali Khan, Todd H Baron, Faisal Kamal, Bilal Ali, Richard Nollan, Mohammad Kashif Ismail, Claudio Tombazzi, Everson L A Artifon, Alessandro Repici, Mouen A Khashab
Background and study aims There is burgeoning interest in the utilization of covered self-expandable metal stents (CSEMSs) for managing benign biliary stricture (BBS). This systematic review and meta-analysis evaluated cumulative stricture resolution and recurrence rates using CSEMSs and compared performance of CSEMSs and multiple plastic stents (MPS) in BBS management. Method Searches in several databases identified studies including ≥ 10 patients that utilized CSEMSs for BBS treatment. Weighted pooled rates were calculated for stricture resolution and recurrence...
July 2017: Endoscopy
https://www.readbyqxmd.com/read/28543841/role-of-fluorescence-in-situ-hybridization-in-diagnosing-cholangiocarcinoma-in-indeterminate-biliary-strictures
#13
Z H Liew, T J Z Loh, T K H Lim, T H Lim, C J L Khor, S J Mesenas, C S C Kong, W C Ong, D M Y Tan
BACKGROUND: Brush cytology, the conventional method to diagnose cholangiocarcinoma, has been plagued by low diagnostic sensitivity and false-negative results. We aim to study the clinical utility of fluorescence in situ hybridization (FISH) in enhancing identification of malignant biliary strictures. METHODS: Brush cytologic specimens collected from endoscopic retrograde cholangiopancreatography (ERCP) for biliary strictures in a tertiary hospital in Singapore from March 2013 to July 2015 were examined by FISH technique using UroVysion probe set in this study...
May 19, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28507752/effective-treatment-of-benign-biliary-strictures-with-a-removable-fully-covered-self-expandable-metal-stent-a-prospective-multicenter-european-study
#14
Arthur Schmidt, Tilman Pickartz, Markus M Lerch, Fabrizio Fanelli, Fausto Fiocca, Pierleone Lucatelli, Fabrizio Cereatti, Albrecht Hoffmeister, Werner van Steenbergen, Matthias Kraft, Benjamin Meier, Karel Caca
BACKGROUND: Temporary placement of removable, fully covered, self-expandable metal stents (fcSEMS) for treatment of benign biliary strictures (BBS) has been reported to be effective. However, the optimal extraction time point remains unclear and stent migration has been a major concern. OBJECTIVE: The objective of this study was to evaluate the efficacy and safety of this treatment modality using an fcSEMS with a special antimigration design and prolonged stent indwell time...
April 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28475277/a-stepwise-procedure-for-removal-of-an-embedded-self-expandable-metallic-stent-by-dual-knife
#15
Ya-Wei Bi, Zhao-Shen Li, Liang-Hao Hu
Benign biliary stricture (BBS) occurs in 7.3%-30.0% patients with chronic pancreatitis(1, 2) . In the management of BBS, fully covered self-expandable metallic stent (FCSEMS) is currently well used(3-5) . However, proximal migration of FCSEMS occurs in 10.0% recipients and is much more difficult to manage(5) . A 44-year-old man was admitted with abdominal pain and recurred obstructive jaundice a month after removal of last biliary plastic stents. This article is protected by copyright. All rights reserved.
May 5, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28411396/the-usefulness-of-adding-p53-immunocytochemistry-to-bile-drainage-cytology-for-the-diagnosis-of-malignant-biliary-strictures
#16
Min-Kyung Yeo, Kyung-Hee Kim, Yong-Moon Lee, Byung Seok Lee, Song-Yi Choi
BACKGROUND: Obstructive jaundice is frequently caused by bile duct strictures. Determination of malignant strictures is crucial for the initiation of appropriate treatment. Cytologic examination of bile drainage fluid is an easy and reproducible method of detecting malignant cells. This method, however, frequently yields indeterminate results, such as atypia or suspicious of malignancy, due to difficulties in differentiating malignancy from benign atypia. Immunocytochemical assessment of p53 expression by cells in bile drainage fluid may enhance the ability to detect malignancy...
April 14, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28406769/dexamethasone-effect-on-the-expression-of-transforming-growth-factor-%C3%AE-1-smads-signaling-pathway-in-benign-biliary-stricture-fibroblasts-in-rodent
#17
Ke -Yue Li, Cheng -Xian Shi, Jian -Zhao Huang, Ke -Li Tang
OBJECTIVE: To investigate the effects of dexamethasone on transforming growth factor (TGF)-β1/Smads signaling pathway in benign biliary stricture (BBS) fibroblasts. STUDY DESIGN: An experimental study. PLACE AND DURATION OF STUDY: Guizhou Medical University, Guiyang, Guizhou, China, from January to August 2016. METHODOLOGY: Fibroblasts derived from rabbit BBS model were cultured and identified, then treated by different concentration of dexamethasone (0...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28337833/acute-cholangitis-current-concepts
#18
REVIEW
David Lan Cheong Wah, Christopher Christophi, Vijayaragavan Muralidharan
BACKGROUND: Acute cholangitis, also known as ascending cholangitis, is a life-threatening systemic condition that results from a biliary tree infection and obstruction. Severe acute cholangitis was reported to have a mortality rate between 11 and 27% in the 1990s. This article is a literature review about acute cholangitis. Its aim is to review the latest literature about acute cholangitis and to discuss its pathogenesis, clinical presentation, diagnosis, prognosis, risk factors and treatment...
July 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28314602/endoscopic-rendez-vous-reconstruction-of-complete-biliary-obstruction
#19
B Neu, S Nennstiel, S von Delius, M Abdelhafez, M Bajbouj, R M Schmid, H Berger, H Feussner, A Meining
BACKGROUND AND STUDY AIMS: Complete biliary strictures normally require surgical intervention. We describe an alternative, minimally invasive endoscopic/percutaneous rendez-vous technique for the reconstruction of complete benign biliary strictures. PATIENTS AND METHODS: Complete biliary strictures were reconstructed in four patients using a rendez-vous percutaneous-endoscopic or percutaneous-percutaneous route guided by fluoroscopic and visual (transillumination) control...
February 27, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28301778/risk-stratified-versus-non-risk-stratified-diagnostic-testing-for-management-of-suspected-acute-biliary-obstruction-comparative-effectiveness-costs-and-the-role-of-mr-cholangiopancreatography
#20
Stella K Kang, David Hoffman, Bart Ferket, Michelle I Kim, R Scott Braithwaite
Purpose To analyze the cost-effectiveness of the American Society for Gastrointestinal Endoscopy (ASGE) risk stratification guidelines versus magnetic resonance (MR) cholangiopancreatography-based treatment of patients with possible choledocholithiasis. Materials and Methods A decision-analytic model was constructed to compare cost and effectiveness of three diagnostic strategies for gallstone disease with possible choledocholithiasis: noncontrast MR cholangiopancreatography, contrast material-enhanced MR imaging/MR cholangiopancreatography, and ASGE risk stratification guidelines for diagnostic evaluation recommending endoscopy (high risk), MR cholangiopancreatography (intermediate risk), or no test (low risk)...
August 2017: Radiology
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