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https://www.readbyqxmd.com/read/29327313/reduction-of-pain-sensitivity-after-somatosensory-therapy-in-children-with-autism-spectrum-disorders
#1
Inmaculada Riquelme, Samar M Hatem, Pedro Montoya
Children with autism spectrum disorders (ASD) often present with somatosensory dysfunction including an abnormal reactivity to tactile stimuli and altered pain perception. A therapy based on somatosensory stimuli has shown effectiveness in reducing pain sensitivity among adults with cerebral palsy. The present study aims at exploring the influence of somatosensory therapy on somatosensory parameters in children with ASD. Children with high-functioning ASD were randomly assigned to either the intervention (n = 29) or the control group (n = 30)...
January 12, 2018: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/29325223/maternal-thyroid-hormone-insufficiency-during-pregnancy-and-risk-of-neurodevelopmental-disorders-in-offspring-a-systematic-review-and-meta-analysis
#2
William Thompson, Ginny Russell, Genevieve Baragwanath, Justin Matthews, Bijay Vaidya, Jo Thompson-Coon
BACKGROUND: In the last two decades, several studies have examined the association between maternal thyroid hormone insufficiency during pregnancy and neurodevelopmental disorders in children and shown conflicting results. AIM: This systematic review aimed to assess the evidence for an association between maternal thyroid hormone insufficiency during pregnancy and neurodevelopmental disorders in children. We also sought to assess whether levothyroxine treatment for maternal thyroid hormone insufficiency improves child neurodevelopment outcomes...
January 11, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29316336/enhancing-interactions-during-daily-routines-a-randomized-controlled-trial-of-a-web-based-tutorial-for-parents-of-young-children-with-asd
#3
Lisa V Ibañez, Kenneth Kobak, Amy Swanson, Lisa Wallace, Zachary Warren, Wendy L Stone
Children with Autism Spectrum Disorder (ASD) often experience difficulty participating in everyday home routines, such as bed time or bath time. This randomized controlled trial examined the efficacy of an interactive, web-based parenting tutorial for improving children's engagement in daily routines (i.e., proximal outcomes) as well improving children's social communication and parenting efficacy and stress (i.e., broad outcomes). Parents of children with ASD between 18 and 60 months were randomly assigned to the Tutorial group (n = 52) or the Control group (n = 52)...
January 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29306218/toddlers-at-risk-for-autism-spectrum-disorders-from-kerala-india-a-community-based-screening
#4
Jaisoorya Ts, Preeti Jacob, Shoba Srinath, Sunil Kumar G, Manoj L, Gokul Gr, Diana L Robins, Thennarasu K
AIMS: To study the at-risk rate for Autism Spectrum Disorders (ASD) on a parent-report questionnaire in toddlers between the ages of 16-24 months. MATERIALS AND METHODS: 6237 toddlers from Kerala, India selected by cluster random sampling were surveyed by community nurses using the Modified Checklist for Autism in Toddlers - Revised (M-CHAT-R) translated to Malayalam and culturally adapted. RESULTS: 5.5% toddlers were at risk on M-CHAT-R and 2...
December 28, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29299606/association-of-maternal-use-of-folic-acid-and-multivitamin-supplements-in-the-periods-before-and-during-pregnancy-with-the-risk-of-autism-spectrum-disorder-in-offspring
#5
Stephen Z Levine, Arad Kodesh, Alexander Viktorin, Lauren Smith, Rudolf Uher, Abraham Reichenberg, Sven Sandin
Importance: The association of maternal use of folic acid and multivitamin supplements before and during pregnancy with the risk of autism spectrum disorder (ASD) in offspring is unclear. Objective: To examine the associations between the use of maternal folic acid and multivitamin supplements before and during pregnancy and the risk of ASD in offspring. Design, Setting, and Participants: A case-control cohort study of 45 300 Israeli children born between January 1, 2003, and December 31, 2007, were followed up from birth to January 26, 2015, for the risk of ASD...
January 3, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29287877/evaluation-and-remediation-of-central-auditory-processing-disorders-in-children-with-autism-spectrum-disorders
#6
Hesham Kozou, Hanan Galal Azouz, Rania M Abdou, Alyaa Shaltout
OBJECTIVES: This study was carried out to assess various skills of central auditory processing (CAP) in children with autism spectrum disorders (ASD) and to evaluate the efficacy of auditory training in these children. METHODS: This study is a non-randomized clinical experiment. 30 high functioning ASD children aged from 7 to 12 years were included in the study. They underwent behavioral assessments of CAP skills with subsequent remediation by dichotic training therapy for the children who revealed dichotic deficits...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29286586/cognitive-enhancement-therapy-for-adult-autism-spectrum-disorder-results-of-an-18-month-randomized-clinical-trial
#7
Shaun M Eack, Susan S Hogarty, Deborah P Greenwald, Maralee Y Litschge, Shannondora A Porton, Carla A Mazefsky, Nancy J Minshew
Cognitive remediation is a promising approach to treating core cognitive deficits in adults with autism, but rigorously controlled trials of comprehensive interventions that target both social and non-social cognition over a sufficient period of time to impact functioning are lacking. This study examined the efficacy of cognitive enhancement therapy (CET) for improving core cognitive and employment outcomes in adult autism. Verbal adult outpatients with autism spectrum disorder (N = 54) were randomized to an 18-month, single-blind trial of CET, a cognitive remediation approach that integrates computer-based neurocognitive training with group-based training in social cognition, or an active enriched supportive therapy (EST) comparison focused on psychoeducation and condition management...
December 29, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29280711/efficacy-of-occupational-therapy-using-ayres-sensory-integration%C3%A2-a-systematic-review
#8
Roseann C Schaaf, Rachel L Dumont, Marian Arbesman, Teresa A May-Benson
This systematic review addresses the question "What is the efficacy of occupational therapy using Ayres Sensory Integration® (ASI) to support functioning and participation as defined by the International Classification of Functioning, Disability and Health for persons with challenges in processing and integrating sensory information that interfere with everyday life participation?" Three randomized controlled trials, 1 retroactive analysis, and 1 single-subject ABA design published from 2007 to 2015, all of which happened to study children with autism, met inclusion criteria...
January 2018: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/29274502/subtyping-cognitive-profiles-in-autism-spectrum-disorder-using-a-random-forest-algorithm
#9
E Feczko, N Balba, O Miranda-Dominguez, M Cordova, S L Karalunas, L Irwin, D V Demeter, A P Hill, B H Langhorst, J Grieser Painter, J Van Santen, E J Fombonne, J L Nigg, D A Fair
DSM-5 Autism Spectrum Disorder (ASD) comprises a set of neurodevelopmental disorders characterized by deficits in social communication and interaction and repetitive behaviors or restricted interests, and may both affect and be affected by multiple cognitive mechanisms. This study attempts to identify and characterize cognitive subtypes within the ASD population using a random forest (RF) machine learning classification model. We trained our model on measures from seven tasks that reflect multiple levels of information processing...
December 20, 2017: NeuroImage
https://www.readbyqxmd.com/read/29262472/-structural-change-of-the-corpus-callosum-fibers-in-toddlers-with-autism-spectrum-disorder-two-year-follow-up
#10
C Chang, N N Qiu, T Xiao, X Xiao, K K Chu, Y Li, Q R Wu, H Fang, X Y Ke
Objective: To conduct a follow-up investigation of structural changes of the corpus callosum fibers of toddlers (2 to 5 years of age) with autism spectrum disorder(ASD) and to explore the associations with clinical symptoms. Method: In this prospective randomized controlled study, ASD children who were diagnosed in the Child Mental Health Research Center, Nanjing Brain Hospital Affiliated to Nanjing Medical University from May 2011 to November 2012 were included in the ASD group, and developmentally delayed children were included in the control group (DD group)...
December 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29262470/-sleep-problems-and-the-association-with-the-levels-of-6-sulfatoxymelatonin-in-children-with-autism-spectrum-disorder
#11
P P Han, M Y Zou, X L Yang, X C Liu, S Liang, C H Sun, W Xia, L J Wu
Objective: To identify the prevalence of sleep problems in children with autism spectrum disorder (ASD) and to explore the association with the main melatonin metabolite, 6-sulfatoxymelatonin (6-SM). Method: This was a prospective case-control study. Children with ASD were recruited from Child Development and Behavioral Research Center (CDBRC) of the Harbin Medical University and Harbin Special Education School from October 2015 to April 2017 (ASD group) . Healthy controls were selected from five kindergartens and one primary school in Harbin by the stratified cluster random sampling (control group) ...
December 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29241345/effects-of-attentional-focus-on-motor-learning-in-children-with-autism-spectrum-disorder
#12
Andy Cy Tse
Inability to acquire a new motor skill is a common motor difficulty in children with autism spectrum disorder. The purpose of this study is to examine whether the motor learning benefits of an external focus of attention for typically developing children and children with intellectual disabilities could also be applied to children with autism spectrum disorder. Children ( N = 65; mean age = 10.01 years) diagnosed with high-functioning autism spectrum disorder were randomly assigned into one of the three groups: external focus ( n = 22), internal focus ( n = 22), and control ( n = 21)...
December 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29238390/modulatory-effect-of-association-of-brain-stimulation-by-light-and-binaural-beats-in-specific-brain-waves
#13
Mauricio Rocha Calomeni, Vernon Furtado da Silva, Bruna Brandão Velasques, Olavo Guimarães Feijó, Juliana Marques Bittencourt, Alair Pedro Ribeiro de Souza E Silva
Introduction: One of the positive effects of brain stimulation is interhemispheric modulation as shown in some scientific studies. This study examined if a type of noninvasive stimulation using binaural beats with led-lights and sound would show different modulatory effects upon Alfa and SMR brain waves of elderlies and children with some disease types. Subjects: The sample included 75 individuals of both genders, being, randomly, divided in 6 groups. Groups were named elderly without dementia diagnosis (EWD), n=15, 76±8 years, elderly diagnosed with Parkinson's disease (EDP), n=15, 72±7 years, elderly diagnosed with Alzheimer's disease (EDA), n=15, 81±6 years...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29238311/assessing-risk-of-bias-in-randomized-controlled-trials-for-autism-spectrum-disorder
#14
Paola Matiko Martins Okuda, Cheryl Klaiman, Jessica Bradshaw, Morganne Reid, Hugo Cogo-Moreira
Aim: To determine construct validity and reliability indicators of the Cochrane risk of bias (RoB) tool in the context of randomized clinical trials (RCTs) for autism spectrum disorder (ASD). Methods: Confirmatory factor analysis was used to evaluate a unidimensional model consisting of 9 RoB categorical indicators evaluated across 94 RCTs addressing interventions for ASD. Results: Only five of the nine original RoB items returned good fit indices and so were retained in the analysis...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29237275/an-exploratory-longitudinal-study-of-social-and-language-outcomes-in-children-with-autism-in-bilingual-home-environments
#15
Vanessa Zhou, Jeffrey A Munson, Jessica Greenson, Yan Hou, Sally Rogers, Annette M Estes
Little is known about outcomes of early intervention for children with autism spectrum disorder reared in bilingual homes. There are concerns that social communication deficits among children with autism spectrum disorder may reduce the developmental benefits of early intervention for children with autism spectrum disorder raised in bilingual environments. We conducted an exploratory analysis of cross-sectional and longitudinal data from a larger study to explore associations between home language environment and language ability and social skills in response to early autism spectrum disorder intervention...
December 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29234931/a-pilot-randomized-controlled-trial-of-the-access-program-a-group-intervention-to-improve-social-adaptive-functioning-stress-coping-and-self-determination-outcomes-in-young-adults-with-autism-spectrum-disorder
#16
Tasha M Oswald, Breanna Winder-Patel, Steven Ruder, Guibo Xing, Aubyn Stahmer, Marjorie Solomon
The purpose of this pilot randomized controlled trial was to investigate the acceptability and efficacy of the Acquiring Career, Coping, Executive control, Social Skills (ACCESS) Program, a group intervention tailored for young adults with autism spectrum disorder (ASD) to enhance critical skills and beliefs that promote adult functioning, including social and adaptive skills, self-determination skills, and coping self-efficacy. Forty-four adults with ASD (ages 18-38; 13 females) and their caregivers were randomly assigned to treatment or waitlist control...
December 12, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29226773/exercise-effects-for-children-with-autism-spectrum-disorder-metabolic-health-autistic-traits-and-quality-of-life
#17
Chrystiane V A Toscano, Humberto M Carvalho, José P Ferreira
This study examined the effects of a 48-week exercise-based intervention on the metabolic profile, autism traits, and perceived quality of life in children with autism spectrum disorder (ASD). We randomly allocated 64 children with ASD (aged 6-12 years) to experimental ( n = 46) and control groups ( n = 18) and used multilevel regression modeling to examine responses to receiving or not receiving the intervention. The experimental group showed beneficial effects on metabolic indicators (high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and total cholesterol), autism traits, and parent-perceived quality of life...
January 1, 2017: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29216519/mine-is-better-than-yours-investigating-the-ownership-effect-in-children-with-autism-spectrum-disorder-and-typically-developing-children
#18
Calum Hartley, Sophie Fisher
Ownership has a unique and privileged influence on human psychology. Typically developing (TD) children judge their objects to be more desirable and valuable than similar objects belonging to others. This 'ownership effect' is due to processing one's property in relation to 'the self'. Here we explore whether children with autism spectrum disorder (ASD) - a population with impaired self-understanding - prefer and over-value property due to ownership. In Experiment 1, we discovered that children with ASD did not favour a randomly endowed toy and frequently traded for a different object...
December 4, 2017: Cognition
https://www.readbyqxmd.com/read/29216234/infant-and-dyadic-assessment-in-early-community-based-screening-for-autism-spectrum-disorder-with-the-preaut-grid
#19
Bertrand Olliac, Graciela Crespin, Marie-Christine Laznik, Oussama Cherif Idrissi El Ganouni, Jean-Louis Sarradet, Colette Bauby, Anne-Marie Dandres, Emeline Ruiz, Claude Bursztejn, Jean Xavier, Bruno Falissard, Nicolas Bodeau, David Cohen, Catherine Saint-Georges
BACKGROUND: The need for early treatment of autism spectrum disorders (ASD) necessitates early screening. Very few tools have been prospectively tested with infants of less than 12 months of age. The PREAUT grid is based on dyadic assessment through interaction and shared emotion and showed good metrics for predicting ASD in very-high-risk infants with West syndrome. METHODS: We assessed the ability of the PREAUT grid to predict ASD in low-risk individuals by prospectively following and screening 12,179 infants with the PREAUT grid at four (PREAUT-4) and nine (PREAUT-9) months of age...
2017: PloS One
https://www.readbyqxmd.com/read/29212472/autism-risk-classification-using-placental-chorionic-surface-vascular-network-features
#20
Jen-Mei Chang, Hui Zeng, Ruxu Han, Ya-Mei Chang, Ruchit Shah, Carolyn M Salafia, Craig Newschaffer, Richard K Miller, Philip Katzman, Jack Moye, Margaret Fallin, Cheryl K Walker, Lisa Croen
BACKGROUND: Autism Spectrum Disorder (ASD) is one of the fastest-growing developmental disorders in the United States. It was hypothesized that variations in the placental chorionic surface vascular network (PCSVN) structure may reflect both the overall effects of genetic and environmentally regulated variations in branching morphogenesis within the conceptus and the fetus' vital organs. This paper provides sound evidences to support the study of ASD risks with PCSVN through a combination of feature-selection and classification algorithms...
December 6, 2017: BMC Medical Informatics and Decision Making
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