keyword
MENU ▼
Read by QxMD icon Read
search

Autism randomized

keyword
https://www.readbyqxmd.com/read/29773920/effects-of-emergent-literacy-interventions-for-preschoolers-with-autism-spectrum-disorder
#1
Roxanne F Hudson, Elizabeth A Sanders, Rosanne Greenway, Sharon Xie, Maya Smith, Colin Gasamis, Jay Martini, Ilene Schwartz, Jacob Hackett
Combining data from a series of three planned, consecutive independent randomized controlled trials (RCTs), the present study investigates two literacy interventions for preschool children with autism spectrum disorder (ASD). For the first cohort, children were randomized to interactive book reading treatment (IBR)or a business-as-usual (BAU) control condition; in Cohort 2, children were randomized to phonological awareness treatment (PA)or BAU; in Cohort 3, children were randomized to IBR or PA. Both treatments were implemented weekly in the classroom from November to May...
October 2017: Exceptional Children
https://www.readbyqxmd.com/read/29763417/meta-analyses-of-individual-versus-group-interventions-for-pre-school-children-with-autism-spectrum-disorder-asd
#2
Yoshiyuki Tachibana, Celine Miyazaki, Masashi Mikami, Erika Ota, Rintaro Mori, Yeonhee Hwang, Akiko Terasaka, Eriko Kobayashi, Yoko Kamio
There is little evidence regarding the effects of individual and group intervention for children with autism spectrum disorder (ASD) on important outcomes. We performed meta-analyses using a random effects model to investigate the effectiveness of the individual and group intervention studies and to compare the effectiveness of these two types if possible. The main analysis which excluded studies at a high risk of bias (Analysis I) included 14 randomised controlled trials targeting children with ASD≤6 years of age (594 children)...
2018: PloS One
https://www.readbyqxmd.com/read/29748736/long-term-social-skills-group-training-for-children-and-adolescents-with-autism-spectrum-disorder-a-randomized-controlled-trial
#3
Ulf Jonsson, Nora Choque Olsson, Christina Coco, Anders Görling, Oskar Flygare, Anna Råde, Qi Chen, Steve Berggren, Kristiina Tammimies, Sven Bölte
Social skills group training (SSGT) is widely used for intellectually able children and adolescents with autism spectrum disorder (ASD). Previous studies indicate small to moderate effects on social communication capacities. The duration of most available programs is relatively short, and extended training might lead to further improvement. This randomized controlled trial compared an extended 24-week version of the SSGT program KONTAKT with standard care. The weekly sessions gradually shifted in content from acquisition of new skills to real-world application of the acquired skills...
May 10, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29743090/effectiveness-of-a-multi-level-implementation-strategy-for-asd-interventions-study-protocol-for-two-linked-cluster-randomized-trials
#4
Lauren Brookman-Frazee, Aubyn C Stahmer
BACKGROUND: The Centers for Disease Control (2018) estimates that 1 in 59 children has autism spectrum disorder, and the annual cost of ASD in the U.S. is estimated to be $236 billion. Evidence-based interventions have been developed and demonstrate effectiveness in improving child outcomes. However, research on generalizable methods to scale up these practices in the multiple service systems caring for these children has been limited and is critical to meet this growing public health need...
May 9, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29742275/early-intensive-behavioral-intervention-eibi-for-young-children-with-autism-spectrum-disorders-asd
#5
REVIEW
Brian Reichow, Kara Hume, Erin E Barton, Brian A Boyd
BACKGROUND: The rising prevalence of autism spectrum disorders (ASD) increases the need for evidence-based behavioral treatments to lessen the impact of symptoms on children's functioning. At present, there are no curative or psychopharmacological therapies to effectively treat all symptoms of the disorders. Early intensive behavioral intervention (EIBI) is a treatment based on the principles of applied behavior analysis. Delivered for multiple years at an intensity of 20 to 40 hours per week, it is one of the more well-established treatments for ASD...
May 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29701910/can-you-spot-a-liar-deception-mindreading-and-the-case-of-autism-spectrum-disorder
#6
David M Williams, Toby Nicholson, Catherine Grainger, Sophie E Lind, Peter Carruthers
Detection of deception is of fundamental importance for everyday social life and might require "mindreading" (the ability to represent others' mental states). People with diminished mindreading, such as those with autism spectrum disorder (ASD), might be at risk of manipulation because of lie detection difficulties. In Experiment 1, performance among 216 neurotypical adults on a realistic lie detection paradigm was significantly negatively associated with number of ASD traits, but not with mindreading ability...
April 27, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29694241/a-1-5-year-follow-up-of-parent-training-and-atomoxetine-for-attention-deficit-hyperactivity-disorder-symptoms-and-noncompliant-disruptive-behavior-in-autism
#7
L Eugene Arnold, Nicole Ober, Michael G Aman, Benjamin Handen, Tristram Smith, Xueliang Pan, Susan L Hyman, Jill Hollway, Luc Lecavalier, Kristin Page, Robert Rice
OBJECTIVE: To examine status of children with autism spectrum disorder (ASD) 10 months after a 34-week clinical trial of atomoxetine (ATX) and parent training (PT). METHODS: In a 2 × 2 design, 128 children with ASD and attention-deficit/hyperactivity disorder (ADHD) were randomly assigned ATX, PT+placebo, PT+ATX, or placebo alone. PT was weekly for 10 weeks, and then monthly. ATX/placebo was titrated over 6 weeks [≤1.8 mg/kg/d], and then maintained until week 10...
April 25, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29691794/efficacy-of-the-asap-intervention-for-preschoolers-with-asd-a-cluster-randomized-controlled-trial
#8
Brian A Boyd, Linda R Watson, Stephanie S Reszka, John Sideris, Michael Alessandri, Grace T Baranek, Elizabeth R Crais, Amy Donaldson, Anibal Gutierrez, LeAnne Johnson, Katie Belardi
The advancing social-communication and play (ASAP) intervention was designed as a classroom-based intervention, in which the educational teams serving preschool-aged children with autism spectrum disorder are trained to implement the intervention in order to improve these children's social-communication and play skills. In this 4-year, multi-site efficacy trial, classrooms were randomly assigned to ASAP or a business-as-usual control condition. A total of 78 classrooms, including 161 children, enrolled in this study...
April 24, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29687457/a-randomized-waitlist-controlled-trial-of-cognitive-behavior-therapy-to-improve-emotion-regulation-in-children-with-autism
#9
Jonathan A Weiss, Kendra Thomson, Priscilla Burnham Riosa, Carly Albaum, Victoria Chan, Andrea Maughan, Paula Tablon, Karen Black
BACKGROUND: Mental health problems are common among individuals with autism spectrum disorder (ASD), and difficulties with emotion regulation processes may underlie these issues. Cognitive behavior therapy (CBT) is considered an efficacious treatment for anxiety in children with ASD. Additional research is needed to examine the efficacy of a transdiagnostic treatment approach, whereby the same treatment can be applied to multiple emotional problems, beyond solely anxiety. The purpose of the present study was to examine the efficacy of a manualized and individually delivered 10-session, transdiagnostic CBT intervention, aimed at improving emotion regulation and mental health difficulties in children with ASD...
April 23, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29682095/brain-responses-underlying-anthropomorphism-agency-and-social-attribution-in-autism-spectrum-disorder
#10
Carla J Ammons, Constance F Doss, David Bala, Rajesh K Kana
Background: Theory of Mind (ToM), the ability to attribute mental states to oneself and others, is frequently impaired in Autism Spectrum Disorder (ASD) and may result from altered activation of social brain regions. Conversely, Typically Developing (TD) individuals overextend ToM and show a strong tendency to anthropomorphize and interpret biological motion in the environment. Less is known about how the degree of anthropomorphism influences intentional attribution and engagement of the social brain in ASD...
2018: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/29676605/meta-analysis-of-big-five-personality-traits-in-autism-spectrum-disorder
#11
Jennifer Lodi-Smith, Jonathan D Rodgers, Sara A Cunningham, Christopher Lopata, Marcus L Thomeer
The present meta-analysis synthesizes the emerging literature on the relationship of Big Five personality traits to autism spectrum disorder. Studies were included if they (1) either (a) measured autism spectrum disorder characteristics using a metric that yielded a single score quantification of the magnitude of autism spectrum disorder characteristics and/or (b) studied individuals with an autism spectrum disorder diagnosis compared to individuals without an autism spectrum disorder diagnosis and (2) measured Big Five traits in the same sample or samples...
April 1, 2018: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29656107/statistical-testing-and-power-analysis-for-brain-wide-association-study
#12
Weikang Gong, Lin Wan, Wenlian Lu, Liang Ma, Fan Cheng, Wei Cheng, Stefan Grünewald, Jianfeng Feng
The identification of connexel-wise associations, which involves examining functional connectivities between pairwise voxels across the whole brain, is both statistically and computationally challenging. Although such a connexel-wise methodology has recently been adopted by brain-wide association studies (BWAS) to identify connectivity changes in several mental disorders, such as schizophrenia, autism and depression, the multiple correction and power analysis methods designed specifically for connexel-wise analysis are still lacking...
April 5, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29651456/systematic-reconstruction-of-autism-biology-from-massive-genetic-mutation-profiles
#13
Weijun Luo, Chaolin Zhang, Yong-Hui Jiang, Cory R Brouwer
Autism spectrum disorder (ASD) affects 1% of world population and has become a pressing medical and social problem worldwide. As a paradigmatic complex genetic disease, ASD has been intensively studied and thousands of gene mutations have been reported. Because these mutations rarely recur, it is difficult to (i) pinpoint the fewer disease-causing versus majority random events and (ii) replicate or verify independent studies. A coherent and systematic understanding of autism biology has not been achieved. We analyzed 3392 and 4792 autism-related mutations from two large-scale whole-exome studies across multiple resolution levels, that is, variants (single-nucleotide), genes (protein-coding unit), and pathways (molecular module)...
April 2018: Science Advances
https://www.readbyqxmd.com/read/29644586/brief-report-autism-spectrum-disorder-a-comprehensive-survey-of-randomized-controlled-trials
#14
Samuel Tromans, Clive Adams
We searched the Cochrane Central Register of Controlled Trials to provide an overview of evidence from randomized controlled trials (RCTs) of therapeutic interventions for autism spectrum disorders. From the final survey (529 RCTs), the mean size was 49 participants (standard deviation 50, range 1-479, median 36, mode 40), with a sharp increase in the number of RCTs from 2008. The most frequently evaluated intervention was antipsychotic treatment (n = 44, 3006 participants). The journal with the most RCTs was the Journal of Autism and Developmental Disorders (N = 104)...
April 11, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29644582/a-randomized-placebo-controlled-cross-over-pilot-study-of-riluzole-for-drug-refractory-irritability-in-autism-spectrum-disorder
#15
Logan K Wink, Ryan Adams, Paul S Horn, Charles R Tessier, Andrew P Bantel, Michael Hong, Rebecca C Shaffer, Ernest V Pedapati, Craig A Erickson
Riluzole is a glutamatergic modulator of particular interest in autism spectrum disorder (ASD). In this 12-week randomized, double-blind, placebo-controlled, crossover pilot study we evaluated the safety and tolerability of 5-week of adjunctive riluzole treatment (vs. 5-week of placebo, with 2-week washout period) targeting ASD-associated drug-refractory irritability in eight individuals age 12-25 years. All participants tolerated riluzole 200 mg per day, however there were no statistically significant findings for the overall treatment effect, the treatment effect by week within period of the study, or a cross-over effect across the periods of the study on the Clinical Global Impression Improvement Scale or the Aberrant Behavior Checklist Irritability subscale...
April 11, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29643711/dental-utilization-and-expenditures-by-children-and-adolescents-with-autism-spectrum-disorders-a-population-based-cohort-study
#16
Kai-Chun Chang, Ling-Yi Wang, Jen-Hung Wang, Cheng-Kuang Shaw, Ming-Jay Hwang, Chih-Hao Wu, Huai-Kuan Huang
Objectives: It is understood that children and adolescents with autism spectrum disorders (ASDs) have difficulty in receiving dental treatment. This study explores the differences in dental utilization and expenditure between two groups: children and adolescents with and without ASD. Different conditions that affect these results will be examined, including area of residence, category of treatment, and preferences concerning type of dental institution in Taiwan. Materials and Methods: The health service research database of the National Health Research Institutes, which features population-based, randomly selected samples collected from 2001 to 2010, was utilized in this study...
January 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29629638/fluctuations-in-clinical-symptoms-with-changes-in-serum-25-oh-vitamin-d-levels-in-autistic-children-three-cases-report
#17
Feiyong Jia, Ling Shan, Bing Wang, Honghua Li, Junyan Feng, Zhida Xu, Khaled Saad
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder caused by complicated interactions between genetic and environmental factors. Clinical trials, including case reports, case-control studies, and a double-blinded randomized clinical study, have suggested that high-dose vitamin D3 regimens may ameliorate the core symptoms of ASD. Vitamin D3 supplementation was effective in about three-quarters of children with ASD. To further investigate the relationship between vitamin D and ASD symptoms in vitamin D-responsive autistic children, changes in symptoms were assessed in three children with ASD who were given vitamin D3 supplementation followed by a long interruption...
April 8, 2018: Nutritional Neuroscience
https://www.readbyqxmd.com/read/29620914/effects-of-metformin-on-spatial-and-verbal-memory-in-children-with-asd-and-overweight-associated-with-atypical-antipsychotic-use
#18
Michael G Aman, Jill A Hollway, Jeremy Veenstra-VanderWeele, Benjamin L Handen, Kevin B Sanders, James Chan, Eric Macklin, L Eugene Arnold, Taylor Wong, Cassandra Newsom, Rianne Hastie Adams, Sarah Marler, Naomi Peleg, Evdokia A Anagnostou
OBJECTIVES: Studies in humans and rodents suggest that metformin, a medicine typically used to treat type 2 diabetes, may have beneficial effects on memory. We sought to determine whether metformin improved spatial or verbal memory in children with autism spectrum disorder (ASD) and overweight associated with atypical antipsychotic use. METHODS: We studied the effects of metformin (Riomet® ) concentrate on spatial and verbal memory in 51 youth with ASD, ages 6 through 17 years, who were taking atypical antipsychotic medications, had gained significant weight, and were enrolled in a trial of metformin for weight management...
April 5, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29610408/family-characteristics-and-children-s-receipt-of-autism-services-in-low-resourced-families
#19
Elizabeth A Karp, Rebecca Dudovitz, Bergen B Nelson, Wendy Shih, Amanda Gulsrud, Felice Orlich, Costanza Colombi, Alice A Kuo
OBJECTIVES: Parents of children with autism spectrum disorder (ASD) face competing demands when caring for their child and fulfilling family commitments. It remains unknown whether family obligations and parental stress might decrease the use of intervention services for young children with ASD. METHODS: The current study is a secondary analysis of baseline date from a published randomized control trial with 147 low-resourced caregiver-child dyads. Demographic information, data on service use, maternal employment, parent's perception of their child's development, and parental stress were collected for primary caregivers of 2- to 5-year-old children with ASD from 5 sites...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29609630/rationale-and-design-for-cognitive-behavioral-therapy-for-anxiety-disorders-in-children-with-autism-spectrum-disorder-a-study-protocol-of-a-randomized-controlled-trial
#20
Tina R Kilburn, Merete Juul Sørensen, Mikael Thastum, Ronald M Rapee, Charlotte Ulrikka Rask, Kristian Bech Arendt, Per Hove Thomsen
BACKGROUND: Autism spectrum disorder (ASD) is found in approximately 1% of the population and includes core symptoms that affect general and social development. Beside these core symptoms, it is suggested that up to 60% of children with ASD suffer from comorbid anxiety disorders which may further affect educational, social and general development as well as quality of life. The main goal of this study is to examine the effectiveness of a manualized cognitive behavioral therapy (CBT) anxiety program adapted for children with ASD...
April 2, 2018: Trials
keyword
keyword
94526
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"