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https://www.readbyqxmd.com/read/28732566/association-of-circulating-irisin-levels-with-metabolic-and-metabolite-profiles-of-korean-adolescents
#1
Han Byul Jang, Hyo-Jin Kim, Jae Heon Kang, Sang Ick Park, Kyung Hee Park, Hye-Ja Lee
CONTEXT: Irisin, a novel exercise-induced myokine, has been suggested to regulate energy metabolism. OBJECTIVE: We studied the relationship between circulating irisin and metabolic and metabolite profiles of Korean adolescents, and investigated the effects of physical activity, obesity, and metabolic syndrome (MetS) on irisin levels. MATERIALS AND METHODS: Data were obtained from the Korean Children-Adolescents Study. Our cross-sectional study included 618 adolescents (370 normal-weight and 248 obese adolescents; 316 boys and 302 girls) aged 12-15years...
August 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28728752/nano-structured-antimicrobial-surfaces-from-nature-to-synthetic-analogues
#2
REVIEW
Aaron Elbourne, Russell J Crawford, Elena P Ivanova
The scientific and industrial interest in antimicrobial surfaces has significantly increased in recent times. This interest is largely in response to the persistent microbial contamination of industrial and, importantly, medical implant surfaces. Bacterial contamination of implant surfaces often leads to infection at the implant-tissue interface, and with the prevalence of increasing levels of antimicrobial resistance, the treatment of these infections is becoming far more challenging. Recently, many naturally occurring, high-aspect-ratio surface topographies have been discovered that exhibit high levels of biocidal efficacy...
July 8, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28719492/fifty-men-3510-marathons-cardiac-risk-factors-and-coronary-artery-calcium-scores
#3
William O Roberts, Robert S Schwartz, Ross F Garberich, Samantha Carlson, Thomas Knickelbine, Jonathan G Schwartz, Gretchen Peichel, John R Lesser, Kelly Wickstrom, Kevin M Harris
INTRODUCTION/PURPOSE: Many male marathon runners have elevated coronary artery calcium (CAC) scores despite high physical activity. We examined the association between CAC scores, cardiovascular risk factors, and lifestyle habits in long term marathoners. METHODS: We recruited men who had run ≥1 marathon annually for 25 consecutive years. CAC was assessed using coronary computed tomography angiography. Atherosclerotic cardiovascular disease (CAD) risk factors were measured with a 12-lead ECG, serum lipid panel, height, weight, resting blood pressure and heart rate, and a risk factor questionnaire...
July 17, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28716139/elevated-c-reactive-protein-interleukin-6-tumor-necrosis-factor-alpha-and-glycemic-load-associated-with-type-2-diabetes-mellitus-in-rural-thais-a-cross-sectional-study
#4
Chanchira Phosat, Pornpimol Panprathip, Noppanath Chumpathat, Pattaneeya Prangthip, Narisara Chantratita, Ngamphol Soonthornworasiri, Somchai Puduang, Karunee Kwanbunjan
BACKGROUND: The elevated levels of inflammatory markers, including C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), and interleukin 6 (IL6) are supposed to be associated with type 2 diabetes mellitus (T2DM). Frequent high glycemic load (GL) consumption, central obesity, and a lack of physical activity are considered to be T2DM risk factors. This study aimed to determine the difference of these inflammatory markers as well as GL in individuals with versus those without T2DM in rural Thais...
July 17, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28704597/are-incident-gallstones-associated-to-sex-dependent-changes-with-age-a-cohort-study
#5
D M Shabanzadeh, S A Holmboe, L T Sørensen, A Linneberg, A-M Andersson, T Jørgensen
Age and female sex have repeatedly been identified as gallstone determinants but the underlying mechanisms are not clarified. The objectives of this study were to determine if changes with age in physiology, lifestyle, or reproductive hormones were associated with incident gallstones. A cohort study of a general population random sample (N = 2366) aged 30-60 years was performed. Participants were ultrasound screened for gallstones in 1982-84 and again in 1993-94. Lifestyle data and blood samples were obtained and re-analyzed in 2004...
July 13, 2017: Andrology
https://www.readbyqxmd.com/read/28704534/short-term-variation-in-ntprobnp-after-lifestyle-intervention-in-severe-obesity
#6
Debora Fedele, Virginia Bicchiega, Alessandro Collo, Federica Barutta, Erika Pistone, Gabriella Gruden, Graziella Bruno
AIM: Natriuretic peptides are not only involved in cardiovascular adaption to various conditions, but also in metabolic diseases. We performed this study to assess the effect of a very short time of lifestyle inpatient intervention on NTproBNP values in normotensive subjects with severe obesity and normal cardiac function. METHODS: We recruited 14 consecutive obese normotensive subjects with normal cardiac function who were aged 30 years and more and were referred to inpatient rehabilitation in an academic clinic over a two months period...
2017: PloS One
https://www.readbyqxmd.com/read/28700959/relationship-between-physical-activity-practice-and-metabolic-profile-of-postmenopausal-women-under-treatment-with-aromatase-inhibitors-for-breast-cancer
#7
Thais R S de Paulo, Juliana Viezel, Bruna L Aro, Sylvia C Seidinger, Ana Carolina A C Trindade, Diego G D Christofaro, Ismael F Freitas
OBJECTIVE: To analyze the relationship between physical activity practice and metabolic profile of postmenopausal women under treatment with aromatase inhibitors (AIs) for the treatment of breast cancer. STUDY DESIGN: Cross-sectional study, conducted with 101 postmenopausal women (aged 50-80 years). The sample was divided into two groups; group without cancer (GW; n=65) and breast cancer group treated with AIs (GC; n=36). Physical activity (PA) was evaluated by questionnaire...
July 5, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28699499/effectiveness-of-argan-oil-on-knee-osteoarthritis-symptoms-a-randomized-controlled-clinical-trial
#8
Jamila Essouiri, Taoufik Harzy, Nadia Benaicha, Mourad Errasfa, Abourazzak Fatima Ezzahra
BACKGROUND: Knee osteoarthritis (KOA) is a common chronic degenerative disorder. It causes joints pain, walking difficulties and a decline of general physical function. Many pain drugs and treatment modalities can be prescribed for KOA. Among traditional medicine in Morocco, Argan oil has been used in the treatment of knee osteoarthritis to reduce pain and improve physical activity, though there have been no medical-based evidence for such treatment. Argan oil is known to have anti-oxidant and lipid modulatory properties due to its content of many substances, such as tocopherols, phytosterols, saturated and unsaturated fatty acids...
July 10, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28698350/efficacy-of-nanocurcumin-supplementation-on-insulin-resistance-lipids-inflammatory-factors-and-nesfatin-among-obese-patients-with-non-alcoholic-fatty-liver-disease-nafld-a-trial-protocol
#9
Seyed Ali Jazayeri-Tehrani, Seyed Mahdi Rezayat, Siavash Mansouri, Mostafa Qorbani, Seyed Moayed Alavian, Milad Daneshi-Maskooni, Mohammad-Javad Hosseinzadeh-Attar
OBJECTIVES: Different studies have been conducted on the role of curcumin in health since having multiple properties, including antioxidant and anti-inflammatory effects. Due to the lack of studies regarding curcumin effects on obese patients with non-alcoholic fatty liver disease (NAFLD), our protocol was designed to assess nanocurcumin impacts on blood sugar, lipids, inflammatory indices, insulin resistance and liver function, especially by nesfatin. SETTING: This trial will be conducted in the Oil Company central hospital of Tehran, Iran with a primary level of care...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28691397/cyanidin-3-glucoside-increases-whole-body-energy-metabolism-by-upregulating-brown-adipose-tissue-mitochondrial-function
#10
Yilin You, Xiaoxue Yuan, Xiaomeng Liu, Chen Liang, Minghui Meng, Yuanyuan Huang, Xue Han, Jielong Guo, Yu Guo, Chenglong Ren, Qianwen Zhang, Xiangyu Sun, Tingting Ma, Guojie Liu, Wanzhu Jin, Weidong Huang, Jicheng Zhan
SCOPE: Obesity develops when energy intake exceeds energy expenditure. Promoting brown adipose tissue (BAT) formation and function increases energy expenditure and may protect against obesity. Cyanidin-3-glucoside (C3G) is an anthocyanin compound which occurs naturally in many fruits and vegetables. In this study, we investigated the effect and mechanism of C3G on the prevention of obesity. METHODS AND RESULTS: Db/db mice received C3G dissolved in drinking water for 16 weeks; Drinking water served as the vehicle treatment...
July 10, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28688988/bactericidal-activity-of-self-assembled-palmitic-and-stearic-fatty-acid-crystals-on-highly-ordered-pyrolytic-graphite
#11
Elena P Ivanova, Song Ha Nguyen, Yachong Guo, Vladimir A Baulin, Hayden K Webb, Vi Khanh Truong, Jason V Wandiyanto, Christopher J Garvey, Peter J Mahon, David E Mainwaring, Russell J Crawford
The wings of insects such as cicadas and dragonflies have been found to exhibit nanostructure arrays that are assembled from fatty acids, and that physically interact with and significantly disrupt bacterial cell membranes. Such mechanobactericidal surfaces are of significant interest, as they can kill bacteria without the need for antibacterial chemicals. Here, we report on the bactericidal effect of two main lipid components of insect wings epicuticle, palmitic (C16) and stearic (C18) fatty acid films after re-crystallisation on the surface of highly ordered pyrolytic graphite...
July 5, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28686191/the-gene-lifestyle-interaction-on-leptin-sensitivity-and-lipid-metabolism-in-adults-a-population-based-study
#12
Harry Freitag Luglio, Dian Caturini Sulistyoningrum, Emy Huriyati, Yi Yi Lee, Wan Abdul Manan Wan Muda
BACKGROUND: Obesity has been associated with leptin resistance and this might be caused by genetic factors. The aim of this study was to investigate the gene-lifestyle interaction between -866G/A UCP2 (uncoupling protein 2) gene polymorphism, dietary intake and leptin in a population based study. METHODS: This is a cross sectional study conducted in adults living at urban area of Yogyakarta, Indonesia. Data of adiposity, lifestyle, triglyceride, high density lipoprotein (HDL) cholesterol, leptin and UCP2 gene polymorphism were obtained in 380 men and female adults...
July 7, 2017: Nutrients
https://www.readbyqxmd.com/read/28664691/influence-of-protein-deficient-diet-vitamin-b-sub-2-sub-supplementation-and-physical-training-on-serum-composition-of-polyunsaturated-fatty-acids-pufas-in-rats
#13
Aneta Lewicka, Sławomir Lewicki, Anna Kłos, Bogdan Dębski, Tomasz Kurył, Jerzy Bertrandt
[b]Introduction[/b]. Prolonged shortages of protein in the diet significantly alter the composition and content of polyunsaturated fatty acids (PUFA) in tissues and body fluids. One of nutritional factors which may reduce negative effects of protein malnutrition might be vitamin B[sub]2[/sub] due to its influence on lipids metabolism. [b]Objective. [/b]The aim of the study was to investigate the influence of low protein (LP) diet enriched with vitamin B[sub]2[/sub] on the content and composition of PUFA in the blood serum of rats treated with dosed physical exercise...
May 11, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28663239/secretory-phospholipase-a2-group-iia-pla2g2a-modulates-insulin-sensitivity-and-metabolism
#14
Michael S Kuefner, Kevin Pham, Jeanna R Redd, Erin J Stephenson, Innocence Harvey, Xiong Deng, Dave Bridges, Eric Boilard, Marshall B Elam, Edwards A Park
Secretory phospholipase A2 group IIA (PLA2G2A) is a member of a family of secretory phospholipases which have been implicated in inflammation, atherogenesis and antibacterial actions. Here, we evaluated the role of PLA2G2A in the metabolic response to a high fat diet. C57BL/6 mice do not express PLA2g2a due to a frameshift mutation. We fed C57BL/6 mice expressing the human PLA2G2A gene (IIA+ mice) a fat diet and assessed the physiologic response. After 10 weeks on the high fat diet, the C57BL/6 mice were obese, but the IIA+ mice did not gain weight or accumulate lipid...
June 29, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/28662555/cardiovascular-disease-risk-factors-after-an-employer-based-risk-reduction-program-an-observational-cohort-study
#15
David H Holben, Chelsea Rambo, Cheryl Howe, Deborah H Murray, Jay H Shubrook
Context: The burden of cardiovascular disease (CVD) continues to be a public health concern. Workplace interventions that focus on modifying lifestyle habits may reduce CVD risk factors in people at risk. Objective: To determine the effectiveness of a comprehensive lifestyle intervention program that integrated dietary modification, physical activity, stress management, and behavior modification counseling to reduce the risk of CVD in at-risk adults. Methods: Twelve 1-year cohorts who participated in a comprehensive employer-sponsored lifestyle intervention program targeting diet, exercise, behavior modification, and stress management between 2006 and 2010 at a rural university in Appalachian Ohio were studied...
July 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28655124/evaluation-in-terms-of-dietary-habits-of-rheumatic-process-a-clinical-study
#16
Özgür Taşpınar, İhami Gültepe, Yaşar Keskin, Teoman Aydın, Müge Kepekçi, Ahmet Serdar Mutluer, İknur Türk Hocaoglu
OBJECTIVE: The aim of this study is the show to comparison between dietary habits of Ankylosing spondylitis (AS) and rheumatoid arthritis (RA) patient. METHODS: In this context, 56 RA patient which are diagnose by American Collage of Rhuomatology-2010 (ACR) rheumatoid arthritis criteria and 28 AS patient which are diagnose by Modified New York Criteria evaluated with their nutrititional status, after that by this evaluation a related form filled by face to face interview in rheumatology outpatient clinic of Physical Therapy and Rehabilitation Department of Bezmialem Vakif University...
June 3, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28654182/the-d-lactate-dehydrogenase-modld1-is-essential-for-growth-and-infection-related-development-in-magnaporthe-oryzae
#17
Tengsheng Zhou, Li Qin, Xiaohan Zhu, Wenyun Shen, Jitao Zou, Zonghua Wang, Yangdou Wei
Rice blast disease caused by Magnaporthe oryzae is initiated by the attachment of conidia to plant surfaces. Germ tubes emerging from conidia develop melanized appressoria to physically penetrate the host surface. Previous studies revealed that appressorium development requires the breakdown of storage lipids and glycogen that occur in peroxisomes and the cytosol respectively, culminating in production of pyruvate. However, the downstream product(s) entering the mitochondria for further oxidation is unclear...
May 18, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28652525/sugar-sweetened-beverages-consumption-positively-associated-with-the-risks-of-obesity-and-hypertriglyceridemia-among-children-aged-7-18-years-in-south-china
#18
Baoting He, Weiqing Long, Xiuhong Li, Wenhan Yang, Yajun Chen, Yanna Zhu
AIMS: Excessive consumption of sugar-sweetened beverages (SSBs) may increase the prevalence of obesity and other metabolic risk factors. However, data regarding the relationship between SSB consumption and metabolic risk factors are insufficient in Chinese children. Hence, we aimed to explore the association between SSB consumption and cardio-metabolic risk factors in children aged 7-18 years living in South China. METHODS: A cross-sectional study was conducted in a total of 2,032 children aged 7-18 years were enrolled, including 1,013 boys and 1,019 girls...
June 23, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28651395/-analysis-of-dietary-pattern-and-diabetes-mellitus-influencing-factors-identified-by-classification-tree-model-in-adults-of-fujian
#19
F L Yu, Y Ye, Y S Yan
Objective: To find out the dietary patterns and explore the relationship between environmental factors (especially dietary patterns) and diabetes mellitus in the adults of Fujian. Methods: Multi-stage sampling method were used to survey residents aged ≥18 years by questionnaire, physical examination and laboratory detection in 10 disease surveillance points in Fujian. Factor analysis was used to identify the dietary patterns, while logistic regression model was applied to analyze relationship between dietary patterns and diabetes mellitus, and classification tree model was adopted to identify the influencing factors for diabetes mellitus...
May 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28645028/lipid-homeostasis-and-regulated-cell-death
#20
REVIEW
Eran Agmon, Brent R Stockwell
Modern lipidomics analysis paints a dynamic picture of membrane organizations, as changing and adapting lipid assemblies that play an active role in cellular function. This article highlights how the lipid composition of membranes determines specific organelle functions, how homeostatic mechanisms maintain these functions by regulating physical properties of membranes, and how cells disrupt lipid homeostasis to bring about regulated cell death (RCD). These are broad phenomena, and representative examples are reviewed here...
June 20, 2017: Current Opinion in Chemical Biology
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