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https://www.readbyqxmd.com/read/29338956/gender-identity-disparities-in-cancer-screening-behaviors
#1
Ariella R Tabaac, Megan E Sutter, Catherine S J Wall, Kellan E Baker
INTRODUCTION: Transgender (trans) and gender-nonconforming adults have reported reduced access to health care because of discrimination and lack of knowledgeable care. This study aimed to contribute to the nascent cancer prevention literature among trans and gender-nonconforming individuals by ascertaining rates of breast, cervical, prostate, and colorectal cancer screening behaviors by gender identity. METHODS: Publicly available de-identified data from the 2014-2016 Behavioral Risk Factor Surveillance System surveys were utilized to evaluate rates of cancer screenings by gender identity, while controlling for healthcare access, sociodemographics, and survey year...
January 12, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29287053/diagnostic-performance-of-one-off-flexible-sigmoidoscopy-with-fecal-immunochemical-testing-in-a-large-screening-population
#2
Tobias Niedermaier, Korbinian Weigl, Michael Hoffmeister, Hermann Brenner
BACKGROUND: Flexible sigmoidoscopy and fecal immunochemical tests are established diagnostic tests for colorectal cancer (CRC) screening and less invasive, less expensive, and easier to conduct than colonoscopy. However, little is known about their joint diagnostic performance compared to colonoscopy. We aimed to assess the expected diagnostic performance of joint use of flexible sigmoidoscopy and fecal immunochemical test. METHODS: We assessed the overall and site-specific prevalences of colorectal neoplasms and the overall and site-specific sensitivity, specificity, area under the receiver operating characteristics curve of a quantitative fecal immunochemical test (FOB Gold) among 3,466 participants in screening colonoscopy in Germany...
December 28, 2017: Epidemiology
https://www.readbyqxmd.com/read/29246283/greater-adherence-to-a-mediterranean-diet-is-associated-with-lower-prevalence-of-colorectal-adenomas-in-men-of-all-races
#3
Alyson Haslam, Sara Wagner Robb, James R Hébert, Hanwen Huang, Mark H Ebell
To examine potential racial differences in Mediterranean diet scores and whether these differences are associated with the prevalence of colorectal adenoma (CRA), a cross-sectional analysis of data from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial was performed. The authors hypothesize that people consuming a more Mediterranean-like diet have lower odds of CRA. Flexible sigmoidoscopy was used to determine the presence of colorectal adenoma. Mediterranean diet scores were calculated from food frequency questionnaire responses...
December 2017: Nutrition Research
https://www.readbyqxmd.com/read/29225617/fecal-calprotectin-a-reliable-predictor-of-mucosal-healing-after-treatment-for-active-ulcerative-colitis
#4
Vendel Kristensen, Arne Røseth, Tahir Ahmad, Viggo Skar, Bjørn Moum
Objectives: Mucosal healing has become the new goal of treatment in ulcerative colitis. Fecal calprotectin has been demonstrated to differentiate between mucosal inflammation and mucosal healing. With this project, we investigated whether a reduction in f-calprotectin to <250 μg/g after medical treatment for active ulcerative colitis could predict mucosal healing. Material and Methods: After a baseline colonoscopy, 20 patients with active ulcerative colitis were followed with consecutive fecal calprotectin monthly until two measurements of fecal calprotectin < 250 μg/g or a maximum follow-up of 12 months...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29205835/colonoscopy-conversion-after-flexible-sigmoidoscopy-screening-results-from-the-uk-bowel-scope-screening-programme
#5
Keith Siau, Andrew Yew, Sauid Ishaq, Sarah Jewes, Sharan Shetty S, Matthew Brookes, Andrew Veitch, Brian McKaig, Aravinth Murugananthan
INTRODUCTION: In the UK Bowel Scope screening programme (BSSP), patients progress to colonoscopy based on high-risk features on flexible sigmoidoscopy (FS). OBJECTIVE: To assess practice of colonoscopy conversion and predictors of additional adenoma detection on colonoscopy. DESIGN: The Bowel Cancer Screening database was interrogated and collated with endoscopic and histological findings from patients undergoing colonoscopy following FS between August 2013 and August 2016...
December 5, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29197686/the-impact-of-screening-on-cancer-incidence-and-mortality-in-missouri-usa-2004-2013
#6
Y Yoshida, C L Schmaltz, J Jackson-Thompson, E J Simoes
OBJECTIVES: Population-based evidence regarding impact of cancer screenings and cancer rates in Missouri is lacking. This study examined whether screenings of breast cancer, cervical cancer, and colorectal cancer impact early-stage cancer incidence and mortality in Missouri. STUDY DESIGN: This is an ecological study based on county-specific estimates of selected cancer screening prevalence and early-stage cancer incidence and cancer mortality. METHODS: County-specific prevalence of clinical breast examination, mammography, Pap test, sigmoidoscopy or colonoscopy, and fecal occult blood test (FOBT) were generated from Missouri County-Level Study (2003, 2007, and 2011)...
November 30, 2017: Public Health
https://www.readbyqxmd.com/read/29174953/signature-celebration-of-gastroenterology-colorectal-cancer
#7
Andrew T Chan, Paul Moayyedi
Gastroenterology has published many seminal articles that have transformed our understanding of colorectal cancer (CRC) as well as being influential in promoting colorectal cancer screening which has saved many people from developing the disease. CRC has a hereditary component most notably highlighted in Lynch syndrome. A key paper reported that the majority of mutations in patients with hereditary nonpolyposis colorectal cancer harbored mutations in the MLH1 or MSH2 mismatch repair proteins. Continuing on the gene mutation theme, another paper...
November 23, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29168060/the-role-of-physician-recommendation-in-colorectal-cancer-screening-receipt-among-immigrant-chinese-americans
#8
Jane Jih, Minh P Nguyen, Irene Ly, Janice Y Tsoh, Gem M Le, Kent Woo, Elaine Chan, Ginny Gildengorin, Susan L Stewart, Adam Burke, Rena Pasick, Stephen J McPhee, Tung T Nguyen
Chinese Americans have low colorectal cancer (CRC) screening rates. It is unclear whether physicians should offer all CRC screening modalities (fecal occult blood test [FOBT], sigmoidoscopy, colonoscopy) to Chinese Americans to increase screening. Seven hundred and twenty-five Chinese Americans were asked in a survey if their physician had ever recommended CRC screening and to self-report receipt and type of CRC screening. Participants whose physician had recommended all CRC screening modalities were significantly more likely to report ever having screening (adjusted odds ratio 4...
November 22, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29153075/is-whole-colon-investigation-by-colonoscopy-computerised-tomography-colonography-or-barium-enema-necessary-for-all-patients-with-colorectal-cancer-symptoms-and-for-which-patients-would-flexible-sigmoidoscopy-suffice-a-retrospective-cohort-study
#9
Wendy Atkin, Kate Wooldrage, Urvi Shah, Kate Skinner, Jeremy P Brown, Willie Hamilton, Ines Kralj-Hans, Michael R Thompson, Karen G Flashman, Steve Halligan, Siwan Thomas-Gibson, Margaret Vance, Amanda J Cross
BACKGROUND: For patients referred to hospital with suspected colorectal cancer (CRC), it is current standard clinical practice to conduct an examination of the whole colon and rectum. However, studies have shown that an examination of the distal colorectum using flexible sigmoidoscopy (FS) can be a safe and clinically effective investigation for some patients. These findings require validation in a multicentre study. OBJECTIVES: To investigate the links between patient symptoms at presentation and CRC risk by subsite, and to provide evidence of whether or not FS is an effective alternative to whole-colon investigation (WCI) in patients whose symptoms do not suggest proximal or obstructive disease...
November 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29123576/the-efficacy-and-safety-of-the-biosimilar-product-inflectra%C3%A2-compared-to-the-reference-drug-remicade%C3%A2-in-rescue-therapy-in-adult-patients-with-ulcerative-colitis
#10
Magdalena Kaniewska, Andrzej Moniuszko, Grażyna Rydzewska
Introduction: The biosimilar product Inflectra® has been approved by the European Medicine Agency (EMA) for the same indications as its reference drug, infliximab, based on studies in patients with rheumatic diseases. Thus far, there have not been enough data regarding its efficacy and safety in ulcerative colitis (UC). Aim: To assess the efficacy and safety of the biosimilar product Inflectra® in comparison with its reference biological agent (Remicade®) in rescue therapy in adult patients presenting with severe exacerbation of UC, as well as to evaluate recurrence rate during a 6-month observation after finish of treatment...
2017: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29118559/long-term-efficacy-of-vacuum-assisted-therapy-endo-sponge%C3%A2-in-large-anastomotic-leakages-following-anterior-rectal-resection
#11
Alessandro Mussetto, Rosario Arena, Andrea Buzzi, Lorenzo Fuccio, Silvia Dari, Mario Luciano Brancaccio, Omero Triossi
Background: The aim of our study was to test the long-term efficacy of Endo-SPONGE® therapy in a group of patients treated in our center with vacuum-assisted therapy because of anastomotic leakages after colorectal surgery. Methods: Eleven patients [male: 6; mean age: 71 (range: 44-82) years] who had anastomotic leakage treated with Endo-SPONGE® placement were included in the study. Patient records were examined retrospectively. All patients with documented anastomotic leakage on abdominal computed tomography following an anterior resection of the rectum for rectal cancer underwent sigmoidoscopy to determine the extent of the anastomotic defect and the size of the presacral abscess...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29104169/asymptomatic-clostridium-difficile-carriage-rate-post-fecal-microbiota-transplant-is-low-a-prospective-clinical-and-stool-assessment
#12
Jessica R Allegretti, Andrew Allegretti, Emmalee Phelps, Huiping Xu, Zain Kassam, Monika Fischer
OBJECTIVES: We aimed to assess the asymptomatic C. difficile carriage rates following FMT. METHODS: All patients who underwent FMT for recurrent CDI via colonoscopy or sigmoidoscopy between June 2013 and April 2015 and had a minimum of 8-week follow-up post-FMT at two tertiary care referral centers were included in the study. Patients were prospectively followed both clinically and with stool assessments for 8 weeks post FMT. Assessments occurred at 1 week and 4 weeks post-FMT to assess for failure...
November 2, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29101688/racial-disparities-and-factors-affecting-michigan-colorectal-cancer-screening
#13
Vincent Grzywacz, Nasir Hussain, Neli Ragina
INTRODUCTION: The objective of this study was to investigate the various factors that influence colorectal cancer screening in Michigan using 6091 participants in the Michigan Behavioral Risk Factor Surveillance System representing adults ≥ 50 years old. METHODS: Screening for colorectal cancer was assessed as fecal occult blood testing or colonoscopy/sigmoidoscopy. Full models simultaneously adjusted for alcohol use, angina/coronary heart disease, stroke, heart attack, gender, income, marital status, race, age, diabetes, disability, exercise, health care coverage, health care access, smoking, and mental health...
November 3, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29099422/the-endoscopic-and-histologic-findings-of-infants-who-have-experienced-brief-resolved-unexplained-events
#14
Chaowapong Jarasvaraparn, Maria B R Gallegos, Madhuri S Mulekar, Bin Wang, David A Gremse, Karen D Crissinger
INTRODUCTION: A brief resolved unexplained event (BRUE) describes an event associated with a change in muscle tone, color, respiration, and responsiveness that is unexplained after an appropriate examination. Some infants with higher risk BRUE may undergo endoscopy as part of their evaluation. OBJECTIVE: This retrospective study aimed to identify the endoscopic findings in infants who have experienced a higher risk BRUE. We also compared the characteristics, prenatal, natal, and postnatal risk factors between 23 infants who underwent endoscopic evaluation and 23 race-matched/sex-matched/term-matched/preterm-matched infants who did not undergo endoscopic evaluation...
November 2, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29075916/a-novel-endoscopic-treatment-for-anastomotic-leakage-post-anterior-resection-padlock-over-the-scope-clip
#15
Callum Robertson, Francesca Savioli, Kawan Shalli
BACKGROUND: Anastomotic dehisense is a serious complication of anterior resections. We have had success in our centre utilising Endosponge therapy to salvage anastomotic leaks but this requires multiple endoscopic sessions and can take around 6 weeks to heal in some cases. This can delay further management such as chemotherapy. AIM: We describe the novel use of Padlock over the scope clips to manage patients with anastomotic dehisense post anterior resection. METHOD: Padlock over the scope clips were used to manage three patients who presented with anastomotic breakdown post laparoscopic anterior resection between February 2016 and July 2017...
October 26, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29073707/-french-comment-on-article-acceptability-of-two-colorectal-cancer-screening-tests-pain-as-a-key-determinant-in-sigmoidoscopy
#16
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Endoscopy
https://www.readbyqxmd.com/read/29067154/a-positive-sehcat-test-results-in-fewer-subsequent-investigations-in-patients-with-chronic-diarrhoea
#17
James M Turner, Sanjeev S Pattni, Richard N Appleby, Julian Rf Walters
Chronic diarrhoea is a common condition, resulting from a number of different disorders. Bile acid diarrhoea, occurring in about a third of these patients, is often undiagnosed. We hypothesised that a positive diagnosis of bile acid diarrhoea would reduce the need for subsequent investigations for alternative diagnoses. METHODS: Patients previously recruited to a study of chronic diarrhoea who had selenium homocholic acid taurine (SeHCAT) testing and subsequent follow-up at our institution were identified...
October 2017: Frontline Gastroenterology
https://www.readbyqxmd.com/read/29057085/the-evaluation-of-risk-benefit-ratio-for-gut-tissue-sampling-in-hiv-cure-research
#18
EDITORIAL
Vikram Mehraj, Peter Ghali, Rayoun Ramendra, Cecilia Costiniuk, Bertrand Lebouché, Rosalie Ponte, Robert Reinhard, Jose Sousa, Nicolas Chomont, Eric A Cohen, Petronela Ancuta, Jean-Pierre Routy
INTRODUCTION: Antiretroviral therapy (ART) does not cure HIV infection due to the persistence of HIV reservoirs in long-lived memory CD4 T cells present in the blood, lymph nodes, intestinal tract, and other tissues. Interest grows in obtaining gut-tissue samples for HIV persistence studies, which poses an ethical challenge to provide study volunteers with adequate information on risks and benefits. Herein we assess the risks and benefits of undergoing gut biopsy procedures for HIV pathogenesis and reservoir studies...
October 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29040021/flexible-sigmoidoscopy-and-ct-colonography-screening-patients-experience-with-and-factors-for-undergoing-screening-insight-from-the-proteus-colon-trial
#19
Carlo Senore, Loredana Correale, Daniele Regge, Cesare Hassan, Gabriella Iussich, Marco Silvani, Arrigo Arrigoni, Lia Morra, Nereo Segnan
Purpose To compare the acceptability of computed tomographic (CT) colonography and flexible sigmoidoscopy (FS) screening and the factors predicting CT colonographic screening participation, targeting participants in a randomized screening trial. Materials and Methods Eligible individuals aged 58 years (n = 1984) living in Turin, Italy, were randomly assigned to be invited to screening for colorectal cancer with FS or CT colonography. After individuals who had died or moved away (n = 28) were excluded, 264 of 976 (27...
October 17, 2017: Radiology
https://www.readbyqxmd.com/read/29033437/acute-anorectal-thrombophlebitis-caused-by-a-protein-c-deficiency
#20
Yuji Eso, Satoshi Yoshiji, Yuto Nakakubo, Minoru Matsuura, Hiroshi Seno
A 46-year-old man visited the emergency department of our hospital with a 3-day history of anal pain, hemorrhaging, and a slight fever. He had previously been diagnosed with protein C deficiency and was prescribed dabigatran, a direct oral anticoagulant. Contrast-enhanced computed tomography showed severe rectal wall thickening with partial defect of enhancement. In addition, sigmoidoscopy revealed a dusky purplish swollen anorectal mucosa just above the dentate line. He was diagnosed with acute anorectal thrombophlebitis, and anticoagulant therapy with heparin was initiated...
October 16, 2017: Internal Medicine
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