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https://www.readbyqxmd.com/read/28298185/general-practitioners-perceptions-of-population-based-bowel-screening-and-their-influence-on-practice-a-qualitative-study
#1
Greer Dawson, Melanie Crane, Claudine Lyons, Anna Burnham, Tara Bowman, Donna Perez, Joanne Travaglia
BACKGROUND: Although largely preventable, Australia has one of the highest rates of bowel cancer in the world. General Practitioners (GPs) have an important role to play in prevention and early detection of bowel cancer, however in Australia this is yet to be optimised and participation remains low. This study sought to understand how GPs' perceptions of bowel screening influence their attitudes to, and promotion of the faecal occult blood test (FOBT), to identify opportunities to enhance their role...
March 15, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28289733/correcting-for-microbial-blooms-in-fecal-samples-during-room-temperature-shipping
#2
Amnon Amir, Daniel McDonald, Jose A Navas-Molina, Justine Debelius, James T Morton, Embriette Hyde, Adam Robbins-Pianka, Rob Knight
The use of sterile swabs is a convenient and common way to collect microbiome samples, and many studies have shown that the effects of room-temperature storage are smaller than physiologically relevant differences between subjects. However, several bacterial taxa, notably members of the class Gammaproteobacteria, grow at room temperature, sometimes confusing microbiome results, particularly when stability is assumed. Although comparative benchmarking has shown that several preservation methods, including the use of 95% ethanol, fecal occult blood test (FOBT) and FTA cards, and Omnigene-GUT kits, reduce changes in taxon abundance during room-temperature storage, these techniques all have drawbacks and cannot be applied retrospectively to samples that have already been collected...
March 2017: MSystems
https://www.readbyqxmd.com/read/28282604/the-fecal-occult-blood-test-as-a-tool-for-improved-outpatient-qualification-for-colonoscopy-a-single-center-experience-and-10-year-follow-up-survey
#3
Zbigniew Banaszkiewicz, Jacek Budzyński, Krzysztof Tojek, Paweł Jarmocik, Jacek Frasz, Marcin Mrozowski, Maciej Świtoński, Arkadiusz Jawień
PURPOSE: Colonoscopy is not widely and easily available in all countries, even for symptomatic patients. This is one of the causes of tumors not being diagnosed until an advanced stage. The aim of this study was to estimate the efficacy of the fecal occult blood test (FOBT) in the diagnostic work-up of outpatients referred to a colorectal unit due to indistinct abdominal symptoms. PATIENTS/METHODS: Among 10418 consecutive symptomatic individuals referred to the outpatient clinic, an immunochemical FOBT (Hem-Check 1(®)) was recommended for 9432 patients with indistinct symptoms as a tool for qualifying them for colonoscopy...
March 7, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28277021/the-chinese-and-korean-american-immigrant-experience-a-mixed-methods-examination-of-facilitators-and-barriers-of-colorectal-cancer-screening
#4
Mary Y Jung, Cheryl L Holt, Diane Ng, Hwa J Sim, Xiaoxiao Lu, Daisy Le, Hee-Soon Juon, Jun Li, Sunmin Lee
OBJECTIVE: Among Asian Americans, colorectal cancer (CRC) is the second leading cause of cancer deaths. Despite strong evidence that screening can reduce CRC-related mortality, fewer Chinese and Koreans receive screening as compared to non-Hispanic whites and blacks. The objective of this study was to examine facilitators and barriers as well as strategies to promote CRC screening in this population. DESIGN: This study employed a mixed-methods design. We conducted 17 key informant interviews and 12 focus groups in the Washington, D...
February 25, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28270725/a-centrally-generated-primary-care-physician-audit-report-does-not-improve-colonoscopy-uptake-after-a-positive-result-on-a-fecal-occult-blood-test-in-ontario-s-coloncancercheck-program
#5
D Stock, L Rabeneck, N N Baxter, L F Paszat, R Sutradhar, L Yun, J Tinmouth
BACKGROUND: Timely follow-up of fecal occult blood screening with colonoscopy is essential for achieving colorectal cancer mortality reduction. In the present study, we evaluated the effectiveness of centrally generated, physician-targeted audit and feedback to improve colonoscopy uptake after a positive fecal occult blood test (fobt) result within Ontario's population-wide ColonCancerCheck Program. METHODS: This prospective cohort study used data sets from Ontario's ColonCancerCheck Program (2008-2011) that were linked to provincial administrative health databases...
February 2017: Current Oncology
https://www.readbyqxmd.com/read/28258145/comparison-of-fecal-collection-methods-for-microbiota-studies-in-bangladesh
#6
Emily Vogtmann, Jun Chen, Muhammad G Kibriya, Yu Chen, Tariqul Islam, Mahbubul Eunes, Alauddin Ahmed, Jabun Naher, Anisur Rahman, Amnon Amir, Jianxin Shi, Christian C Abnet, Heidi Nelson, Rob Knight, Nicholas Chia, Habibul Ahsan, Rashmi Sinha
To our knowledge, fecal microbiota collection methods have not been evaluated in low and middle income countries. Therefore, we evaluated five different fecal sample collections methods for technical reproducibility, stability, and accuracy within the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh. Fifty participants from HEALS provided fecal samples in the clinic which were aliquoted into no solution, 95% ethanol, RNAlater, post-development fecal occult blood test (FOBT) cards, and fecal immunochemical test (FIT) tubes...
March 3, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28248632/faecal-occult-blood-testing-fobt-based-colorectal-cancer-screening-trends-and-predictors-of-non-use-findings-from-the-south-australian-setting-and-implications-for-increasing-fobt-uptake
#7
Kamelia Todorov, Carlene Wilson, Greg Sharplin, Nadia Corsini
Objective The present study used data from three South Australian population health surveys to examine trends in knowledge, recent use and reasons for use or non-use of faecal occult blood testing (FOBT) for colorectal cancer (CRC) screening from 2011 to 2014. Screening awareness and demographic factors related to non-use were also examined.Methods FOBT trends were examined for respondents aged 50-75 years across survey years (n ~ 1000). Logistic regression analyses were undertaken to determine predictors of non-use and reasons for non-use of FOBT based on latest data...
March 2, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28244584/factors-that-could-influence-women-s-participation-in-colorectal-cancer-screening-an-italian-study
#8
G Bocci, G Troiano, G Messina, N Nante, S Civitelli
BACKGROUND: Colorectal cancer (CRC) is the 2nd most common cancer in women worldwide. In Italy, only 50% of people invited to get the Fecal Occult Blood Test (FOBT) decided to do it. Women's participation in breast and cervical screening is, instead, very high (>70%). The aim of our study was to investigate the beliefs, the feelings and the psychological factors that could influence the participation of women in CRC screening. METHODS: We conducted a cross sectional study, in the Hospital of Siena, Central Italy, in 2011...
March 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/28243039/fecal-occult-blood-testing-for-the-prediction-of-small-bowel-pathology-detected-by-capsule-endoscopy-a-systematic-review-and-meta-analysis
#9
Diana E Yung, Sanju Vijayan, Tomer Avni, Sarah Douglas, Uri Kopylov, Anastasios Koulaouzidis
BACKGROUND: Fecal occult blood testing (FOBT) has been suggested as a potential screening tool for small-bowel capsule endoscopy (CE). We conducted a meta-analysis of studies correlating FOBT and CE findings to examine the predictive value of positive FOBT for CE findings. METHODS: PubMed and Embase search. Sensitivity, specificity and diagnostic odds ratios (DORs) were calculated. RESULTS: Six studies were identified. Four used fecal immunochemical testing (FIT), one used FIT and guaiac FOBT, one used hemoglobin/haptoglobin complex testing (Hb/Hpt)...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28239755/increasing-cancer-screening-among-old-order-anabaptist-women-through-specialized-women-s-health-and-integrated-cancer-screening-interventions
#10
Kate McBride, Dionne Gesink
Our objective was to develop, deliver, and evaluate a cancer screening intervention focused on rural Anabaptist communities in Ontario, Canada, to increase routine cancer screenings among women. We carried out three cancer prevention and screening interventions with Old Order Anabaptist women. Each intervention consisted of: transportation to the site, pre-arranged screening services, health teachings, fellowship and shopping, and an evaluative survey. Seventy five women total participated over three interventions...
February 27, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28236518/an-out-of-pocket-cost-removal-intervention-on-fecal-occult-blood-test-attendance
#11
Takahiro Tabuchi, Hiroshi Murayama, Takahiro Hoshino, Tomio Nakayama
INTRODUCTION: To date, no comparative study has assessed the impact of a cost-removal intervention on fecal occult blood testing (FOBT). In 2012, the Japanese government introduced a nationwide project to remove out-of-pocket costs for FOBT. The study objective was to evaluate the differential impact of the intervention on FOBT attendance in the total population and various subgroups. METHODS: This study analyzed 309,103 people in national, repeated cross-sectional studies, observed pre- and post-intervention (2010 and 2013), using covariate-adjusted difference-in-differences estimates to compare intervention and no-intervention groups...
February 21, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28218734/-lesions-detected-in-six-spanish-colorectal-cancer-screening-population-based-programmes-cribea-project-spain
#12
Isabel Portillo Villares, Eunate Arana-Arri, Isabel Idigoras Rubio, Josep Alfons Espinás Piñol, Francisco Pérez Riquelme, Mariola de la Vega Prieto, Alvaro González Aledo, Elena Oceja Setien, Mercedes Vanaclocha Espi, Josefa Ibáñez Cabanell, Dolores Salas Trejo
OBJECTIVE: In this study, the results of six Colorectal Cancer Screening Population Programmes are shown (Catalonia, Valence, Murcia, Cantabria, the Basque Country and the Canary Islands collected between 2005 and 2012. These programmes use the faeces occult blood test (FOBt) biennial. Objective: To determine and compare the results of lesions detected by the programmes, participation, sex, age and test used. METHODS: Retrospective cohort study based on people invited, aged between 50-74 years, in at least a complete round...
February 20, 2017: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/28210537/multilevel-predictors-of-colorectal-cancer-testing-modality-among-publicly-and-privately-insured-people-turning-50
#13
Stephanie B Wheeler, Tzy-Mey Kuo, Anne Marie Meyer, Christa E Martens, Kristen M Hassmiller Lich, Florence K L Tangka, Lisa C Richardson, Ingrid J Hall, Judith Lee Smith, Maria E Mayorga, Paul Brown, Trisha M Crutchfield, Michael P Pignone
Understanding multilevel predictors of colorectal cancer (CRC) screening test modality can help inform screening program design and implementation. We used North Carolina Medicare, Medicaid, and private, commercially available, health plan insurance claims data from 2003 to 2008 to ascertain CRC test modality among people who received CRC screening around their 50th birthday, when guidelines recommend that screening should commence for normal risk individuals. We ascertained receipt of colonoscopy, fecal occult blood test (FOBT) and fecal immunochemical test (FIT) from billing codes...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28190597/costs-of-colorectal-cancer-screening-provision-in-cdc-s-colorectal-cancer-control-program-comparisons-of-colonoscopy-and-fobt-fit-based-screening
#14
Sujha Subramanian, Florence K L Tangka, Sonja Hoover, Janet Royalty, Amy DeGroff, Djenaba Joseph
We assess annual costs of screening provision activities implemented by 23 of the Centers for Disease Control and Prevention's Colorectal Cancer Control Program (CRCCP) grantees and report differences in costs between colonoscopy and FOBT/FIT-based screening programs. We analysed annual cost data for the first three year of the CRCCP (July 2009-June 2011) for each screening provision activity and categorized them into clinical and non-clinical screening provision activities. The largest cost components for both colonoscopy and FOBT/FIT-based programs were screening and diagnostic services, program management, and data collection and tracking...
February 7, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28188568/a-comprehensive-electronic-health-record-based-patient-navigation-module-including-technology-driven-colorectal-cancer-outreach-and-education
#15
Sunny Ajeesh, Rustveld Luis
The purpose of this concept paper is to propose an innovative multifaceted patient navigation module embedded in the Electronic Health Record (EHR) to address barriers to efficient and effective colorectal cancer (CRC) care. The EHR-based CRC patient navigation module will include several patient navigation features: (1) CRC screening registry; (2) patient navigation data, including CRC screening data, outcomes of patient navigation including navigation status (CRC screening referrals, fecal occult blood test (FOBT) completed, colonoscopy scheduled and completed, cancelations, reschedules, and no-shows); (3) CRC counseling aid; and 4) Web-based CRC education application including interactive features such as a standardized colonoscopy preparation guide, modifiable CRC risk factors, and links to existing resources...
February 10, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28182647/performance-analysis-of-a-machine-learning-flagging-system-used-to-identify-a-group-of-individuals-at-a-high-risk-for-colorectal-cancer
#16
Yaron Kinar, Pinchas Akiva, Eran Choman, Revital Kariv, Varda Shalev, Bernard Levin, Steven A Narod, Ran Goshen
Individuals with colorectal cancer (CRC) have a tendency to intestinal bleeding which may result in mild to severe iron deficiency anemia, but for many colon cancer patients hematological abnormalities are subtle. The fecal occult blood test (FOBT) is used as a pre-screening test whereby those with a positive FOBT are referred to colonscopy. We sought to determine if information contained in the complete blood count (CBC) report coud be processed automatically and used to predict the presence of occult colorectal cancer (CRC) in the setting of a large health services plan...
2017: PloS One
https://www.readbyqxmd.com/read/28155016/power-of-screening-tests-for-colorectal-cancer-enhanced-by-high-levels-of-m2-pk-in-addition-to-fobt
#17
Cristina Zaccaro, Ilaria Maria Saracino, Giulia Fiorini, Natale Figura, John Holton, Valentina Castelli, Valeria Pesci, Luigi Gatta, Dino Vaira
Colorectal cancer (CRC) is a multistep process that involves adenoma-carcinoma sequence. CRC can be prevented by routine screening, which can detect precancerous lesions. The aim of this study is to clarify whether faecal occult blood test (i-FOBT), tumor M2 pyruvate kinase (t-M2-PK), and endocannabinoid system molecules (cannabinoid receptors type 1-CB1, type 2-CB2, and fatty acid amide hydrolase-FAAH) might represent better diagnostic tools, alone or in combination, for an early diagnosis of CRC. An immunochemical FOB test (i-FOBT) and quantitative ELISA stool test for t-M2-PK were performed in 127 consecutive patients during a 12 month period...
February 2, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28139497/the-expression-and-significance-of-feces-cyclooxygensae-2-mrna-in-colorectal-cancer-and-colorectal-adenomas
#18
Xiaofeng Li, Lixia Kong, Suhuan Liao, Jing Lu, Lin Ma, Xiaohua Long
BACKGROUND/AIM: This study aims to explore the expression and significance of feces cyclooxygensae-2 (COX-2) mRNA in colorectal cancer and colorectal adenomas. MATERIALS AND METHODS: The expression of feces COX-2 mRNA in colorectal cancer (n = 28), colorectal adenomas (n = 54), and normal control group (n = 11) were examined by reverse transcriptase polymerase chain reaction (RT-PCR). The positive rate of fecal occult blood test (FOBT) were detected in colorectal cancer (n = 30), colorectal adenomas (n = 56), and normal control group (n = 11); the sensitivity of the two methods was also compared...
January 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28117881/comparative-effectiveness-of-screening-strategies-for-colorectal-cancer
#19
Afsaneh Barzi, Heinz-Josef Lenz, David I Quinn, Sarmad Sadeghi
BACKGROUND: Screening for colorectal cancer (CRC) has been successful in decreasing the incidence and mortality from CRC. Although new screening tests have become available, their relative impact on CRC outcomes remains unexplored. This study compares the outcomes of various screening strategies on CRC outcomes. METHODS: A Markov model representing the natural history of CRC was built and validated against empiric data from screening trials as well as the Microstimulation Screening Analysis (MISCAN) model...
January 24, 2017: Cancer
https://www.readbyqxmd.com/read/28089385/tailored-telephone-counselling-to-increase-participation-of-underusers-in-a-population-based-colorectal-cancer-screening-programme-with-faecal-occult-blood-test-a-randomized-controlled-trial
#20
B Denis, G Broc, E A Sauleau, I Gendre, K Gana, P Perrin
BACKGROUND: Despite the involvement of general practitioners, the mailing of several recall letters and of the faecal occult blood test (FOBT) kit, the uptake remains insufficient in the French colorectal cancer-screening programme. Some studies have demonstrated a greater efficacy of tailored telephone counselling over usual care, untailored invitation mailing and FOBT kit mailing. We evaluated the feasibility and the effectiveness of telephone counselling on participation in the population-based FOBT colorectal cancer-screening programme implemented in Alsace (France)...
February 2017: Revue D'épidémiologie et de Santé Publique
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