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https://www.readbyqxmd.com/read/28804005/performance-assessment-of-the-saps-ii-and-sofa-scoring-systems-in-hanta-virus-hemorrhagic-fever-with-renal-syndrome
#1
Zhenjun Yu, Ni Zhou, Ali Li, Jie Chen, Huazhong Chen, Zebao He, Fei Yan, Haihong Zhao, Jiansheng Zhu
BACKGROUND: Hemorrhagic Fever with Renal Syndrome (HFRS), caused by the hantavirus, is a natural infectious disease characterized by fever, hemorrhage and renal damage. China is the most severely endemic area for HFRS in the world. In recent years, critical scoring systems based on quantitative classification have become an important clinical tool for predicting and evaluating the prognosis of critical illness, and provide guidelines for clinical practice. METHODS: The sample comprised 384 patients with HFRS treated in the Taizhou Hospital from January 2006 to February 2017...
August 10, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28703752/effects-of-promotional-materials-on-attitudes-and-fear-towards-colorectal-cancer-screening-among-chinese-older-adults-an-experimental-study
#2
Doris Y P Leung, Joanne M T Chen, Vivian W Q Lou, Eliza M L Wong, Aileen W K Chan, Winnie K W So, Carmen W H Chan
Colorectal cancer (CRC) screening is a cost-effective prevention and control strategy. However, the promotion of CRC screening for older adults may be difficult because reading CRC prevention information may evoke embarrassment, fear, and anxiety towards the screening procedure and cancer diagnosis. This study aims to (1) examine the effects of three promotional materials for CRC screening on the attitudes toward CRC screening tests (screening interest, screening effectiveness, and trust in the screening results) and cancer fear, and (2) to explore the interaction effect of cancer fear with screening effectiveness and trust in the screening results on screening interest of the three screening tests (fecal occult blood test (FOBT), flexible sigmoidoscopy, and colonoscopy) among Chinese older adults...
July 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28691053/performance-report-cards-increase-adenoma-detection-rate
#3
Michael Sai Lai Sey, Andy Liu, Samuel Asfaha, Victoria Siebring, Vipul Jairath, Brian Yan
BACKGROUND AND STUDY AIMS : Adenoma detection rate (ADR) is an important measure of colonoscopy quality, as are polyp, advanced ADR, and adenocarcinoma detection rates. We investigated whether performance report cards improved these outcome measures. PATIENTS AND METHODS : Endoscopists were given report cards comparing their detection rates to the institutional mean on an annual basis. Detection rates were evaluated at baseline, 1 year after report cards (Year 1), and 2 years after report cards (Year 2)...
July 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28689518/colon-cancer-screening-is-it-time-yet
#4
EDITORIAL
Hadi Bhurgri, Sami Samiullah
The month of March is dedicated to Colon Cancer Awareness. Worldwide, colorectal cancer (CRC) incidence has been on the rise. It is currently the third most common cancer in men (746,000 cases, 10.0% of the total) and the second in women (614,000 cases, 9.2% of the total).1 Arecent meta-analysis reported a 61% risk reduction in CRC incidence with colonoscopy.2 Unlike screening programs for breast and prostate cancers, not only has CRC screening reduced mortality from colon cancer and detected early CRC, it has also decreased the incidence of CRC through detection and removal of pre-cancerous lesions...
June 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28664503/predictors-of-colorectal-cancer-knowledge-and-screening-among-asian-americans-aged-50-75-years-old
#5
Hee-Soon Juon, Jenny Guo, Jin Kim, Sunmin Lee
Colorectal cancer, the second leading cause of mortality in the USA, can be prevented with colorectal cancer screening. However, many people who should receive the screening do not get screened. To learn more, this study estimated the prevalence of up-to-date colorectal cancer (CRC) screening and examined the relationship between CRC knowledge and screening compliance among Asian Americans living in the Baltimore-Washington Metropolitan area. The study included a cross-sectional sample of 274 Chinese, Korean, and Vietnamese Americans aged 50-75 years old...
June 29, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28660489/novel-approach-to-fecal-occult-blood-testing-by-assay-of-erythrocyte-specific-microrna-markers
#6
Chung Wah Wu, Xiaoming Cao, Calise K Berger, Patrick H Foote, Douglas W Mahoney, Julie A Simonson, Bradley W Anderson, Tracy C Yab, William R Taylor, Lisa A Boardman, John B Kisiel, David A Ahlquist
BACKGROUND: Fecal occult blood testing (FOBT) has historically relied on methods to detect hemoglobin with no fundamental innovations in decades. AIM: To examine microRNA (miRNA) as a new marker class for FOBT. METHODS: Candidate miRNA markers were identified by small RNA sequencing of human whole blood compared to colorectal epithelia. Markers were tested in human blood cell subsets and blood from non-human species. We assessed assay linearity in blood spiking and marker stability in stool over incubation experiments...
August 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28655982/clinical-impact-of-the-immunochemical-fecal-occult-blood-test-for-colorectal-cancer-screening-in-brazil
#7
Cláudio R Teixeira, Michele L Bonotto, Júlio P Lima, Luciana F Figueiredo, Leonardo Conrado, Carlos Frasca
BACKGROUND: Colorectal cancer (CRC) screening programs based on the fecal occult blood test (FOBT) reduce CRC mortality. We carried out an observational prospective study to determine the accuracy of immunochemical FOBTs for the detection of CRC in individuals at average risk for the disease. METHODS: This population-based study was performed between April 2015 and January 2016 in two gastroenterology referral centers in Southern Brazil. It included 1039 average-risk volunteers aged 50-75 years who were symptom-free for colonic disease...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28648086/lower-morbidity-and-improved-outcomes-in-patients-with-screen-detected-colorectal-cancer
#8
David Mansouri
Screening for colorectal cancer is now integrated into the fabric of healthcare systems across the world, as a wealth of evidence exists as regards its benefits in reducing cancer-specific mortality through the detection of early-stage disease. Options for screening include both endoscopic and stool-based tests, with a majority of countries opting for repeated faecal occult blood screening tests (FOBt). These can be either guaiac-based, as is the current system across the UK, or immunoglobulin-based, as is the case in the accompanying article from Spain...
June 26, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28626067/the-impact-of-a-population-based-screening-program-on-income-and-immigration-related-disparities-in-colorectal-cancer-screening
#9
Tara Kiran, Richard H Glazier, Rahim Moineddin, Sumei Gu, Andrew S Wilton, Lawrence Paszat
A population-based program promoting the Fecal Occult Blood Test (FOBT) for colorectal cancer screening was introduced in 2008 in Ontario, Canada, where opportunistic screening with colonoscopy had been increasing in frequency. We evaluated the impact of the program on income and immigration-related disparities in screening. We used linked administrative data to calculate colorectal cancer screening rates for eligible Ontarians in each year between 2001/02 (n=2,852,619) and 2013/14 (n=4,139,304). We quantified disparities using an "inequality ratio" of screening rates in the most disadvantaged group relative to the most advantaged group...
June 16, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28614895/endocuff-assisted-vs-standard-colonoscopy-in-the-fecal-occult-blood-test-based-uk-bowel-cancer-screening-programme-e-cap-study-a-randomized-trial
#10
Rupam Bhattacharyya, Fergus Chedgy, Kesavan Kandiah, Carole Fogg, Bernard Higgins, Ben Haysom-Newport, Lisa Gadeke, Fergus Thursby-Pelham, Richard Ellis, Patrick Goggin, Gaius Longcroft-Wheaton, Pradeep Bhandari
Background and study aims Up to 25 % colorectal adenomas are missed during colonoscopy. The aim of this study was to investigate whether the endocuff could improve polyp detection in an organized bowel cancer screening program (BCSP). Patients and methods This parallel group, single-blinded, randomized controlled trial included patients with positive fecal occult blood test (FOBT) who were attending for BCSP colonoscopy. The primary outcome was the number of polyps per patient. Secondary outcomes included the number of adenomas per patient, adenoma and polyp detection rates, and withdrawal times...
June 14, 2017: Endoscopy
https://www.readbyqxmd.com/read/28584248/fecal-occult-blood-test-results-of-the-national-colorectal-cancer-screening-program-in-south-korea-2006-2013
#11
John Hoon Rim, Taemi Youk, Jung Gu Kang, Byung Kyu Park, Heon Yung Gee, Jeong-Ho Kim, Jongha Yoo
There has been controversy regarding the clinical utility of fecal occult blood test (FOBT) as a screening tool for colorectal cancer (CRC) in the general population. The purpose of this study was to examine the results of Korea national CRC screening using FOBT from 2006 to 2013 and to evaluate the implementation of the program. We analyzed the results of FOBT, colonoscopy, and the side effects during colonoscopy for the subjects (n = 20,609,909) from the Korea National Health Insurance Cancer Screening database...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28572616/comparison-of-non-invasive-biomarkers-faecal-baff-calprotectin-and-fobt-in-discriminating-ibs-from-ibd-and-evaluation-of-intestinal-inflammation
#12
Yu Fu, Lingli Wang, Cheng Xie, Kaifang Zou, Lei Tu, Wei Yan, Xiaohua Hou
Faecal calprotectin and faecal occult blood test (FOBT) were widely used in the diagnosis and assessment of intestinal inflammation in inflammatory bowel disease (IBD). Recently we identified an excellent new biomarker B cell-activating factor (BAFF) for IBD. Here in this study we compared the efficacy of faecal BAFF, calprotectin and FOBT to find the "best non-invasive marker". Results showed that for discriminating IBD from IBS, BAFF ≥227.3 pg/ml yield 84% sensitivity, 100% specificity, 100% positive predictive value (PPV) and 64% negative predictive value (NPV) while calprotectin ≥50 µg/g yield 76% sensitivity, 93% specificity, 97% PPV and 53% NPV...
June 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28494531/stages-of-adoption-for-fobt-and-colonoscopy-tests-for-colorectal-cancer-screening-in-korea
#13
Nhung Bui Cam, Hana Cho, Yoon Young Lee, Mina Suh, Boyoung Park, Jae Kwan Jun, Yeol Kim, Kui Son Choi
Purpose: While colorectal cancer (CRC) is common in Asian countries, screening for CRC is not. Moreover, CRC screening behaviors in Asian populations remain largely unknown. The present study aimed to investigate the stages of adopting CRC screening in Korea according to screening modality. Materials and Methods: Data were obtained from the 2014 Korean National Cancer Screening Survey, a cross-sectional survey that utilized nationally representative random sampling to investigate cancer screening rates...
May 10, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28493543/contribution-of-patient-physician-and-environmental-factors-to-demographic-and-health-variation-in-colonoscopy-follow-up-for-abnormal-colorectal-cancer-screening-test-results
#14
Melissa R Partin, Amy A Gravely, James F Burgess, David A Haggstrom, Sarah E Lillie, David B Nelson, Sean M Nugent, Aasma Shaukat, Shahnaz Sultan, Louise C Walter, Diana J Burgess
BACKGROUND: Patient, physician, and environmental factors were identified, and the authors examined the contribution of these factors to demographic and health variation in colonoscopy follow-up after a positive fecal occult blood test/fecal immunochemical test (FOBT/FIT) screening. METHODS: In total, 76,243 FOBT/FIT-positive patients were identified from 120 Veterans Health Administration (VHA) facilities between August 16, 2009 and March 20, 2011 and were followed for 6 months...
May 11, 2017: Cancer
https://www.readbyqxmd.com/read/28490420/testing-the-effectiveness-of-a-primary-care-intervention-to-improve-uptake-of-colorectal-cancer-screening-a-randomized-controlled-trial-protocol
#15
Natalie Dodd, Mariko Leanne Carey, Elise Mansfield, Christopher Oldmeadow
BACKGROUND: Screening for colorectal cancer (CRC) significantly reduces mortality associated with this disease. In Australia, the National Bowel Cancer Screening Program provides regular fecal occult blood tests (FOBT) for those aged 50 to 74 years, however, participation rates in the program have plateaued at 36%. Given low uptake in the National Bowel Cancer Screening Program, it is necessary to explore alternate methods to increase CRC screening rates. Primary care is a promising adjunct setting to test methods to increase CRC screening participation...
May 10, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28475117/a-label-free-quantitative-fecal-hemoglobin-detection-platform-for-colorectal-cancer-screening
#16
Gita V Soraya, Thanh C Nguyen, Chathurika D Abeyrathne, Duc H Huynh, Jianxiong Chan, Phuong D Nguyen, Babak Nasr, Gursharan Chana, Patrick Kwan, Efstratios Skafidas
The early detection of colorectal cancer is vital for disease management and patient survival. Fecal hemoglobin detection is a widely-adopted method for screening and early diagnosis. Fecal Immunochemical Test (FIT) is favored over the older generation chemical based Fecal Occult Blood Test (FOBT) as it does not require dietary or drug restrictions, and is specific to human blood from the lower digestive tract. To date, no quantitative FIT platforms are available for use in the point-of-care setting. Here, we report proof of principle data of a novel low cost quantitative fecal immunochemical-based biosensor platform that may be further developed into a point-of-care test in low-resource settings...
May 5, 2017: Biosensors
https://www.readbyqxmd.com/read/28469908/measuring-and-improving-cervical-breast-and-colorectal-cancer-screening-rates-in-a-multi-site-urban-practice-in-toronto-canada
#17
Joshua Feldman, Sam Davie, Tara Kiran
Our Family Health Team is located in Toronto, Canada and provides care to over 35 000 patients. Like many practices in Canada, we took an opportunistic approach to cervical, breast, and colorectal cancer screening. We wanted to shift to a proactive, population-based approach but were unable to systematically identify patients overdue for screening or calculate baseline screening rates. Our initiative had two goals: (1) to develop a method for systematically identifying patients eligible for screening and whether they were overdue and (2) to increase screening rates for cervical, breast, and colorectal cancer...
2017: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/28464181/utility-of-hemoccult-testing-before-therapeutic-anticoagulation-in-venous-thromboembolism
#18
Ryan Urbas, Marwan Badri, Nicole E Albert, Catherine Prince, Barani Mayilvaganan
OBJECTIVES: Fecal occult blood testing (FOBT) is performed routinely before starting therapeutic anticoagulation in patients despite it never being validated to predict gastrointestinal bleeding (GIB) risk. Our objective was to determine the utility in checking the guaiac FOBT test (gFOBT) before initiating therapeutic anticoagulation in patients with a new diagnosis of venous thromboembolism (VTE). METHODS: This was a retrospective chart review that examined patients with a diagnosis of VTE admitted during a 2-year period in one mid-sized tertiary care center...
May 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28463410/long-term-risk-of-colorectal-cancer-after-negative-colonoscopy-in-a-danish-gfobt-screening-cohort
#19
Andreas Bjerrum, Ole Andersen, Anders Fischer, Jan Lindebjerg, Elsebeth Lynge
Faecal occult blood test (FOBT) screening for colorectal cancer (CRC) is implemented in several countries. Approximately half of all screen positive persons have negative colonoscopy, but consensus is lacking on how these persons should be followed up. Health authorities in Denmark and The Netherlands recommend suspending screening for 8-10 years, while patients in UK are invited to screening after 2 years. In this cohort-study, we followed 166,277 individuals invited to FOBT-screening in 2005-2006 and a reference group comprising the remaining 1,240,348 Danes of the same age...
April 30, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28447326/ct-colonography-role-in-fobt-based-screening-programs-for-colorectal-cancer
#20
REVIEW
Lapo Sali, Grazia Grazzini, Mario Mascalchi
Computed tomographic colonography (CTC) is a minimally invasive imaging examination for the colon, and is safe, well tolerated and accurate for the detection of colorectal cancer (CRC) and advanced adenoma. While the role of CTC as a primary test for population screening of CRC is under investigation, the fecal occult blood test (FOBT) has been recommended for population screening of CRC in Europe. Subjects with positive FOBT are invited to undergo total colonoscopy, which has some critical issues, such as suboptimal compliance, contraindications and the possibility of an incomplete exploration of the colon...
August 2017: Clinical Journal of Gastroenterology
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