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https://www.readbyqxmd.com/read/29629708/dipyridamole-loaded-biodegradable-pla-nanoplatforms-as-coatings-for-cardiovascular-stents
#1
Veroniki Bakola, Varvara Karagkiozaki, Aikatherini-Rafailia Tsiapla, Foteini Pappa, Ioannis Moutsios, Eleni Pavlidou, Stergious Logothetidis
Cardiovascular Stents are commonly used for the treatment of Cardiovascular Diseases (CVDs) that in developed societies, are the most frequent causes of mortality and morbidity. Recent years, thorough research and development of Drug Eluting Stents (DES) has been done, with emphasis on coronary stenting to avoid the most common complication, the in-stent thrombosis. Dipyridamole (DPM) is a medication that inhibits blood clot formation. Drug Delivery Nanoplatforms consisting of biodegradable polymers can be fabricated via Electrospinning Deposition, known for its cost-effective and versatile advantages, that produces fibrous scaffolds able of sustainable and controllable drug release...
April 9, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29611137/taxonomic-description-and-genome-sequence-of-halobacillus-marinus-sp-nov-a-novel-strain-isolated-from-chilika-lake-india
#2
Ananta N Panda, Samir Ranjan Mishra, Lopamudra Ray, Surajit Das, Gurdeep Rastogi, Ajit Kumar Pattanaik, Tapan Kumar Adhya, Mrutyunjay Suar, Vishakha Raina
moderately halophilic spore forming, motile, Gram-positive, rod-shaped bacterial strain designated as KGW1T was isolated from water sample of Chilika Lake and characterized taxonomically using polyphasic approach. The strain grew in the presence of 0-25% (w/v) NaCl in marine salt agar media, hydrolyzes casein, and gelatin and shows presence of alkaline proteases. The major cell wall menaquinone was MK7 and major cellular fatty acids were anteiso-C15:0 (44.89%), anteiso-C17:0 (6.18%), isoC15:0 (19.38%), and iso-C16:0 (7...
April 2018: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/29608441/diesel-engine-exhaust-exposure-in-underground-mines-comparison-between-different-surrogates-of-particulate-exposure
#3
Alan da Silveira Fleck, Caroline Couture, Jean-François Sauvé, Pierre-Eric Njanga, Eve Neesham-Grenon, Guillaume Lachapelle, Hugo Coulombe, Stéphane Hallé, Simon Aubin, Jérôme Lavoué, Maximilien Debia
Exposure to diesel particulate matter (DPM) is frequently assessed by measuring indicators of carbon speciation, but these measurements may be affected by organic carbon (OC) interference. Furthermore, there are still questions regarding the reliability of direct-reading instruments (DRI) for measuring DPM, since these instruments are not specific and may be interfered by other aerosol sources. This study aimed to to assess DPM exposure in two underground mines by filter-based methods and DRI; and to assess the relationship between the measures of elemental carbon (EC) and the DRI to verify the association of these instruments to DPM...
April 2, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29534005/perceived-benefits-and-barriers-of-a-community-based-diabetes-prevention-and-management-program
#4
Samantha Shawley-Brzoska, Ranjita Misra
This study examined the perceptions of benefits of and barriers to participating in a community-based diabetes program to improve program effectiveness. The Diabetes Prevention and Management (DPM) program was a twenty-two session, 1-year program, modeled after the evidence-based National Diabetes Prevention Program and AADE7 Self-Care Behaviors framework. Community-based participatory research approach was used to culturally tailor the curriculum. Participants included overweight or obese adults with dysglycemia...
March 13, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29498616/marmoricola-silvestris-sp-nov-a-novel-actinobacterium-isolated-from-alpine-forest-soil
#5
Peter Schumann, De-Chao Zhang, Luís França, Rosa Margesin
A Gram-stain-positive, flagellated, catalase- and cytochrome c oxidase-positive bacterial strain, designated S20-100T , was isolated from alpine forest soil. Growth occurred at a temperature range of 0-30 °C, at pH 6-9 and in the presence of 0-1 % (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequence showed that strain S20-100T was related to the genus Marmoricola and had the highest 16S rRNA gene sequence similarity to Marmoricola ginsengisoli Gsoil 097T (98.4 %) and Marmoricola solisilvae KIS18-7T (98...
March 2, 2018: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29480870/the-clinical-effect-of-rehabilitation-following-arthroscopic-rotator-cuff-repair-a-meta-analysis-of-early-versus-delayed-passive-motion
#6
REVIEW
Shuxiang Li, Han Sun, Xiaomin Luo, Kun Wang, Guofeng Wu, Jian Zhou, Peng Wang, Xiaoliang Sun
BACKGROUND: The argument on the recommended rehabilitation protocol following arthroscopic rotator cuff repair remains to be resolved. So this meta-analysis was presented to evaluate the differences of clinical effects between the 2 distinct rehabilitation protocols after arthroscopic rotator cuff repair. METHODS: The PubMed, Cochrane Library, Web of Science, and EMBASE were systematically searched. Only randomized controlled trials (RCTs) published up to July 25, 2017, comparing early passive motion (EPM) versus delayed passive motion (DPM) rehabilitation protocols following arthroscopic rotator cuff repair were identified...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29478267/a-bayesian-nonparametric-approach-to-causal-inference-on-quantiles
#7
Dandan Xu, Michael J Daniels, Almut G Winterstein
We propose a Bayesian nonparametric approach (BNP) for causal inference on quantiles in the presence of many confounders. In particular, we define relevant causal quantities and specify BNP models to avoid bias from restrictive parametric assumptions. We first use Bayesian additive regression trees (BART) to model the propensity score and then construct the distribution of potential outcomes given the propensity score using a Dirichlet process mixture (DPM) of normals model. We thoroughly evaluate the operating characteristics of our approach and compare it to Bayesian and frequentist competitors...
February 25, 2018: Biometrics
https://www.readbyqxmd.com/read/29462356/nutrient-fortification-of-human-donor-milk-affects-intestinal-function-and-protein-metabolism-in-preterm-pigs
#8
Jing Sun, Yanqi Li, Duc Ninh Nguyen, Martin S Mortensen, Chris H P van den Akker, Tom Skeath, Susanne E Pors, Stanislava Pankratova, Silvia Rudloff, Søren J Sørensen, Douglas G Burrin, Thomas Thymann, Per T Sangild
Background: Nutrient fortification of human milk is often required to secure adequate growth and organ development for very preterm infants. There is concern that formula-based fortifiers (FFs) induce intestinal dysfunction, feeding intolerance, and necrotizing enterocolitis (NEC). Bovine colostrum (BC) may be an alternative nutrient fortifier, considering its high content of protein and milk bioactive factors. Objective: We investigated whether BC was superior to an FF product based on processed bovine milk and vegetable oil to fortify donor human milk (DHM) for preterm pigs, used as a model for infants...
February 16, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29461816/photolytic-reactivity-of-organometallic-chromium-bipyridine-complexes
#9
Benjamin E Olafsen, Giuseppe V Crescenzo, Luke P Moisey, Brian O Patrick, Kevin M Smith
Known stable [Cr(bpy)2 (Ph)2 ](BPh4 ) complexes undergo reductive elimination of biphenyl with visible-light photolysis using household incandescent or compact fluorescent light bulbs. A series of [Cr(R-bpy)2 (Ar)2 ](X) complexes (R = H or CMe3 ; Ar = Ph, C6 H4 -CMe3 , or C6 H4 -OMe; X = I, BPh4 , or PF6 ) were prepared, and the effect of varying the bipyridine and aryl ligands on the UV-visible spectra and electrochemistry of the chromium(III) complexes was investigated. Photolysis of a mixture of two different bis(aryl) complexes gave only the homocoupled biaryl products by1 H NMR and gas chromatography/mass spectrometry analysis...
February 20, 2018: Inorganic Chemistry
https://www.readbyqxmd.com/read/29455178/disabling-pansclerotic-morphoea-of-childhood
#10
Indirakshi Jamalpur, Harikrishna Reddy Mogili, Abhilash Koratala
Disabling pansclerotic morphoea (DPM) of childhood is a severe and often fatal variant of deep morphoea. It usually starts in childhood and rarely seen in adults. The course of the disease is progressive with lifelong morbidity in the form of joint contractures and immobility. The causes of mortality include complications such as sepsis, gangrene and cardiopulmonary involvement. Herein, we discuss the case of a 15-year-old girl with limb deformity and finger contractures, that is, bone involvement. The diagnosis of DPM of childhood was fortuitously made after the correction of limb deformity, when the patient was seen in the dermatology department for evaluation of skin discolouration on the thighs...
February 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29431791/the-disclosure-of-mesoscale-behaviour-of-a-3d-smm-monolayer-on-au-111-through-a-multilevel-approach
#11
Guglielmo Fernandez Garcia, Alessandro Lunghi, Federico Totti, Roberta Sessoli
Here we present a computational study of a full- and a half-monolayer of a Fe4 single molecule magnet ([Fe4(L)2(dpm)6], where H3L = 2-hydroxymethyl-2-phenylpropane-1,3-diol and Hdpm = dipivaloylmethane, Fe4Ph) on an unreconstructed surface of Au(111). This has been possible through the application of an integrated approach, which allows the explicit inclusion of the packing effects in the classical dynamics to be used in a second step in periodic and non-periodic high level DFT calculations. In this way we can obtain access to mesoscale geometrical data and verify how they can influence the magnetic properties of interest of the single Fe4 molecule...
February 12, 2018: Nanoscale
https://www.readbyqxmd.com/read/29405794/assessment-of-lacrimal-resistance-using-a-manometric-tear-duct-irrigation-system
#12
Ebube E Obi, Oyinkan Olurin, Peter M Mota, Zuzana Sipkova, Oana Vonica, Andrew R Pearson
Lacrimal surgery aims to provide a low-resistance tear drainage passage. An assessment of lacrimal resistance guides decisions on surgery. We present results of a modified tear duct irrigation system that reliably measures lacrimal outflow resistance. Patients in a specialist lacrimal clinic had a full work-up to the point of tear duct syringing. The tear ducts were irrigated using a manometric system, which applied a fixed, known head of fluid pressure to a lacrimal cannula. Fluid flow is recorded and the lacrimal resistance derived as fluid pressure/fluid flow (units cmH20 secml-1, for simplicity presented as drops per minute, dpm)...
February 6, 2018: Orbit
https://www.readbyqxmd.com/read/29394806/-a-case-of-intrahepatic-cholangiocarcinoma-with-ductal-plate-malformation-pattern
#13
Mari Sekiya, Kazuhiko Sakamoto, Satoshi Matsukuma, Yoshihiro Tokuhisa, Yukio Tokumitsu, Hiroto Matsui, Shinsuke Kanekiyo, Shinobu Tomochika, Michihisa Iida, Shigeru Takeda, Nobuaki Suzuki, Shigefumi Yoshino, Shoichi Hazama, Yoshinobu Hoshii, Hiroaki Nagano
A 56-year-old man with HCV infection was referred to our hospital for further evaluation and treatment of hepatic tumor. Abdominal enhanced computed tomography demonstrated an S8 hepatic tumor, about 15mm in maximal diameter. The tumor showed enhancement on the arterial phase and washout on equilibrium phase. EOB-MRI scan also showed the hepatic tumor with enhancement in the early phase and washout in the delayed phase. Liver function was normal. Serum AFP and PIVKA- II were normal and CEA and CA19-9 were elevated...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29355388/muscle-structure-and-gene-expression-in-pectoralis-major-muscle-in-response-to-deep-pectoral-myopathy-induction-in-fast-and-slow-growing-commercial-broilers
#14
S Yalcin, K Şahin, M Tuzcu, G Bilgen, S Özkan, G T Izzetoğlu, R Işik
1. The objective of this study was to determine muscle structure and gene expression in pectoralis major (p. major) muscle of broilers in response to deep pectoral myopathy (DPM) induction. 2. A total of 160 chickens from slow- and fast-growing broilers were raised under same conditions. Half of the broilers from each strain were encouraged to wing flap when they reached 2800 g body weight. Pectoralis minor (p. minor) muscle of the broilers was inspected for the occurrence of DPM and p. major samples were collected from broilers with or without DPM...
February 19, 2018: British Poultry Science
https://www.readbyqxmd.com/read/29350024/accurate-quantification-of-radiosulfur-in-chemically-complex-atmospheric-samples
#15
Mang Lin, Mark H Thiemens
An ultralow-level liquid scintillation counting (LSC) technique has been used in measuring radiosulfur (cosmogenic 35 S) in natural samples. The ideal half-life of 35 S (∼87 days) renders it a new way to examine various biogeochemical problems. A major limitation of the technique is that complex chemical compositions in atmospheric samples may lead to color quenching of LSC cocktails, a serious problem prolonging the pretreatment time (>1 week) and hampering the accurate determination of 35 S. For application of the technique where many of the most important atmospheric chemical processes are examined, significant interferences arise and accurate analysis in small samples is not possible...
February 20, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29300809/evaluation-of-1-nitropyrene-as-a-surrogate-measure-for-diesel-exhaust
#16
Erin A Riley, Emily E Carpenter, Joemy Ramsay, Emily Zamzow, Christopher Pyke, Michael H Paulsen, Lianne Sheppard, Terry M Spear, Noah S Seixas, Dale J Stephenson, Christopher D Simpson
We investigated the viability of particle bound 1-nitropyrene (1-NP) air concentration measurements as a surrogate of diesel exhaust (DE) exposure, as compared with industry-standard elemental carbon (EC) and total carbon (TC) measurements. Personal exposures are reported for 18 employees at a large underground metal mine during four different monitoring campaigns. Full-shift personal air exposure sampling was conducted using a Mine Safety and Health Administration (MSHA) compliant diesel particulate matter (DPM) impactor cassette downstream of a GS-1 cyclone pre-selector...
March 12, 2018: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29285939/development-of-a-highly-efficient-hybrid-white-organic-light-emitting-diode-with-a-single-emission-layer-by-solution-processing
#17
Jun-Yi Wu, Show-An Chen
We use a mixed host, 2,6-bis[3-(carbazol-9-yl)phenyl]pyridine blended with 20 wt % tris(4-carbazoyl-9-ylphenyl)amine, to lower the hole-injection barrier, along with the bipolar and high-photoluminescence-quantum-yield (Φp = 84%), blue thermally activated delay fluorescence (TADF) material of 9,9-dimethyl-9,10-dihydroacridine-2,4,6-triphenyl-1,3,5-triazine (DMAC-TRZ) as a blue dopant to compose the emission layer for the fabrication of a TADF blue organic-light-emitting diode (BOLED). The device is highly efficient with the following performance parameters: maximum brightness (Bmax ) = 57586 cd/m2 , maximum current efficiency (CEmax ) = 35...
February 7, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29243994/ultrasonic-characterisation-of-particle-retention-by-a-double-porosity-medium
#18
Ruonan Bai, Abdellah Alem, Hervé Franklin, Alain Tinel, Huaqing Wang, Fatima Kachkouch, Said Taibi, Laurent Bizet
A study was undertaken to characterise the evolution of the clogging of various porous media during filtration experiments. Long-term tracer tests were carried out at various flow velocities. To highlight the effects of intraporosity on transport and retention mechanisms, both single porosity and double porosity media (DPM) were used. The presence of matrix porosity in the two investigated DPM provided additional sites, promoting retention of suspended particles (SP). The particle size distribution (PSD) of the recovered particles increased with time...
December 22, 2017: Environmental Technology
https://www.readbyqxmd.com/read/29240695/energy-efficient-real-time-scheduling-using-dpm-on-mobile-sensors-with-a-uniform-multi-cores
#19
Youngmin Kim, Ki-Seong Lee, Chan-Gun Lee
In wireless sensor networks (WSNs), sensor nodes are deployed for collecting and analyzing data. These nodes use limited energy batteries for easy deployment and low cost. The use of limited energy batteries is closely related to the lifetime of the sensor nodes when using wireless sensor networks. Efficient-energy management is important to extending the lifetime of the sensor nodes. Most effort for improving power efficiency in tiny sensor nodes has focused mainly on reducing the power consumed during data transmission...
December 14, 2017: Sensors
https://www.readbyqxmd.com/read/29240546/the-psychosocial-themes-of-children-with-a-congenital-heart-defect
#20
Ronél van der Watt, Carina Pheiffer, Stephen Brown
Children living with a congenital heart defect (CHD) carry the burden of a condition affecting their biological, psychological, and social functioning. Even though the physical heartbeats of these children might be inaudible and defective, their intra- and inter-personal 'stories in sound' need to be heard and understood. The aim of this research study was to explore these 'stories in sound' in children diagnosed with CHD. A qualitative, exploratory, descriptive study using thematic analysis was conducted. Semi-structured interviews were conducted with six boys and three girls between the ages of eight and fourteen years, who were diagnosed with CHD...
November 2017: Journal of Child and Adolescent Mental Health
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