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https://www.readbyqxmd.com/read/28640236/a-decision-mixture-model-based-method-for-inshore-ship-detection-using-high-resolution-remote-sensing-images
#1
Fukun Bi, Jing Chen, Yin Zhuang, Mingming Bian, Qingjun Zhang
With the rapid development of optical remote sensing satellites, ship detection and identification based on large-scale remote sensing images has become a significant maritime research topic. Compared with traditional ocean-going vessel detection, inshore ship detection has received increasing attention in harbor dynamic surveillance and maritime management. However, because the harbor environment is complex, gray information and texture features between docked ships and their connected dock regions are indistinguishable, most of the popular detection methods are limited by their calculation efficiency and detection accuracy...
June 22, 2017: Sensors
https://www.readbyqxmd.com/read/28614441/prevalence-and-factors-associated-with-minor-psychiatric-disorders-in-hospital-housekeeping-workers
#2
Cintia da Silva Marconato, Ana Carolina de Souza Magnago, Tânia Solange Bosi de Souza Magnago, Graziele de Lima Dalmolin, Rafaela Andolhe, Juliana Petri Tavares
OBJECTIVE: Investigating the prevalence and factors associated with minor psychiatric disorders (MPDs) in Hospital housekeeping workers. METHOD: A cross-sectional study carried out in 2013 with workers from the cleaning service of a public university hospital in Rio Grande do Sul, Brazil. Data were collected through a form containing sociodemographic, occupational, habits and health variables. The Self-Reporting Questionnaire-20 was used in order to evaluate MPDs...
June 12, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28609786/gravimetric-measurements-of-filtering-facepiece-respirators-challenged-with-diesel-exhaust
#3
Swathi Satish, Jacob J Swanson, Kai Xiao, Andrew S Viner, David B Kittelson, David Y H Pui
Elevated concentrations of diesel exhaust have been linked to adverse health effects. Filtering facepiece respirators (FFRs) are widely used as a form of respiratory protection against diesel particulate matter (DPM) in occupational settings. Previous results (Penconek A, Drążyk P, Moskal A. (2013) Penetration of diesel exhaust particles through commercially available dust half masks. Ann Occup Hyg; 57: 360-73.) have suggested that common FFRs are less efficient than would be expected for this purpose based on their certification approvals...
June 13, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28511839/the-implication-of-the-osteolysis-threshold-and-interfacial-gaps-on-periprosthetic-osteolysis-in-cementless-total-hip-replacement
#4
Hamidreza Alidousti, Neil W Bressloff
Osteolysis around joint replacements may develop due to migration of wear particles from the joint space into gaps between the interface bone and the implant where they can accumulate in high concentrations to cause tissue damage. Osteolysis may appear in various postoperative times and morphological shapes which can be generalized into linear and focal. However, there are no clear explanations on the causes of such variations. Patients' degree of sensitivity to polyethylene particles (osteolysis thresholds), the local particle concentration and the access route provided by the interface gaps have been described as determining factors...
May 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28437870/assessing-the-likelihood-and-magnitude-of-a-population-health-benefit-following-the-market-introduction-of-a-modified-risk-tobacco-product-enhancements-to-the-dynamic-population-modeler-dpm-1
#5
Annette M Bachand, Sandra I Sulsky, Geoffrey M Curtin
Researchers and those responsible for evaluating and implementing policies intended to reduce population harm must assess the potential for both intended and unintended consequences associated with those policies. Such assessments should be based on the combined dimensions of magnitude, and thus likelihood, of shifts in exposure patterns needed to produce a population benefit or harm, and magnitude of the expected population benefit or harm. In response to this assessment need, we provide a conceptual description of the dynamic population modeler, DPM(+1), as well as illustrative analyses that estimate the effects on all-cause mortality, life expectancy, and quality of life-adjusted life expectancy if exposure patterns in the population shift from a higher risk product (e...
April 24, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28437852/a-diagnostic-microdosing-approach-to-investigate-platinum-sensitivity-in-non-small-cell-lung-cancer
#6
Si-Si Wang, Maike Zimmermann, Hongyong Zhang, Tzu-Yin Lin, Michael Malfatti, Kurt Haack, Kenneth W Turteltaub, George D Cimino, Ralph de Vere White, Chong-Xian Pan, Paul T Henderson
The platinum-based drugs cisplatin, carboplatin and oxaliplatin are often used for chemotherapy, but drug resistance is common. The prediction of resistance to these drugs via genomics is a challenging problem since hundreds of genes are involved. A possible alternative is to use mass spectrometry to determine the propensity for cells to form drug-DNA adducts-the pharmacodynamic drug-target complex for this class of drugs. The feasibility of predictive diagnostic microdosing was assessed in non-small cell lung cancer (NSCLC) cell culture and a pilot clinical trial...
August 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28425920/development-of-a-fast-monte-carlo-dose-calculation-system-for-online-adaptive-radiation-therapy-quality-assurance
#7
Yuhe Wang, Thomas R Mazur, Justin C Park, Deshan Yang, Sasa Mutic, H Harold Li
No abstract text is available yet for this article.
April 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28415388/targeted-delivery-of-docetaxel-via-pi-pi-stacking-stabilized-dendritic-polymeric-micelles-for-enhanced-therapy-of-liver-cancer
#8
Xiaolong Tang, Shuping Zhou, Xinrong Tao, Jian Wang, Fangyu Wang, Yong Liang
Delivery of taxane-based chemotherapeutics including Docetaxel (DTX) by conventional polymeric micelles still suffers from insufficient stability and rapid premature release during the circulation, which limits their targeting and anticancer efficiency. To conquer these challenges, we developed a novel DTX-loaded Pi-Pi stacking-stabilized dendritic polymeric micelle for targeted therapy of liver cancer. This dendritic polymeric micelle, referred to DPM-DTX-cRGD, was self-assembled from DTX and biodegradable dendritic block copolymers Poly(amidoamine)-poly(γ-benzyl-l-Glutamate)-b-polyethylene glycol-cRGD (PAM-PBLG-b-PEG-cRGD)...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28409073/facial-paralysis-and-hearing-loss-a-rare-manifestation-of-prostate-cancer-metastases
#9
Uroosa Ibrahim, Amina Saqib, Farhan Mohammad, Muhammad R Raza, Nikhil Nalluri, Frank Forte
Dural prostate metastases (DPM) are a rare manifestation of metastatic prostate cancer seen in approximately one to six percent of cases. Presenting symptoms may include signs of elevated intracranial pressure, headache, altered mental status, or cranial nerve palsies. Hearing loss, sensory changes, dysarthria, and dysphagia are rare symptoms in DPM that were present in our patient. We present a case of a 58-year-old male with a known diagnosis of adenocarcinoma of the prostate presenting with symptoms of acute exacerbation of chronic obstructive pulmonary disease (COPD), sub-acute right-sided hearing loss, and right-sided facial paralysis...
March 3, 2017: Curēus
https://www.readbyqxmd.com/read/28400239/efficient-synthesis-of-a-multi-substituted-diphenylmethane-skeleton-as-a-steroid-mimetic
#10
Takashi Misawa, Katsuya Tanaka, Yosuke Demizu, Masaaki Kurihara
Steroids are important components of cell membranes and are involved in several physiological functions. A diphenylmethane (DPM) skeleton has recently been suggested to act as a mimetic of the steroid skeleton. However, difficulties are associated with efficiently introducing different substituents between two phenyl rings of the DPM skeleton, and, thus, further structural development based on the DPM skeleton has been limited. We herein developed an efficient synthetic method for introducing different substituents into two phenyl rings of the DPM skeleton...
March 24, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28400188/devascularized-parenchymal-mass-associated-with-partial-nephrectomy-predictive-factors-and-impact-on-functional-recovery
#11
Wen Dong, Jitao Wu, Chalairat Suk-Ouichai, Elvis Caraballo Antonio, Erick Remer, Jianbo Li, Joseph Zabell, Sudhir Isharwal, Steven C Campbell
PURPOSE: Parenchymal mass loss is the predominant factor associated with functional outcomes after partial nephrectomy (PN), and is primarily due to excised parenchymal mass (EPM) and/or devascularized parenchymal mass (DPM). We evaluate the importance of EPM and DPM relative to functional recovery after PN. MATERIALS AND METHODS: 168 PN patients had necessary studies to determine EPM and DPM and evaluate parenchymal mass changes and functional loss within the operated kidney...
April 8, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28381304/evaluation-of-biosecurity-measures-to-prevent-indirect-transmission-of-porcine-epidemic-diarrhea-virus
#12
Yonghyan Kim, My Yang, Sagar M Goyal, Maxim C-J Cheeran, Montserrat Torremorell
BACKGROUND: The effectiveness of biosecurity methods to mitigate the transmission of porcine epidemic diarrhea virus (PEDV) via farm personnel or contaminated fomites is poorly understood. This study was undertaken to evaluate the effectiveness of biosecurity procedures directed at minimizing transmission via personnel following different biosecurity protocols using a controlled experimental setting. RESULTS: PEDV RNA was detected from rectal swabs of experimentally infected (INF) and sentinel pigs by real-time reverse transcription polymerase chain reaction (rRT-PCR)...
April 5, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28346827/effects-of-cerium-oxide-and-ferrocene-nanoparticles-addition-as-fuel-borne-catalysts-on-diesel-engine-particulate-emissions-environmental-and-health-implications
#13
Zhi-Hui Zhang, Rajasekhar Balasubramanian
This study systematically examined the potential impacts of doping CeO2 and Fe(C5H5)2 nanoparticles as fuel-borne catalysts (FBCs) to ultralow sulfur diesel (ULSD) fuel on the physical, chemical and toxicological characteristics of diesel particulate matter (DPM). The FBCs-doped fuels are effective in promoting soot oxidation and reducing the DPM mass emissions, but lead to a significant increase in the total particle counts due to the formation of self-nucleated metallic nanoparticles. Compared to undoped ULSD, the FBCs-doped fuels result in higher concentrations of particle-phase polycyclic aromatic hydrocarbons (PAHs) and n-alkanes, higher fractions of organic carbon (OC) and water-soluble organic carbon (WSOC) in particles, show slight alterations in soot nanostructure, reduce soot ignition temperature and activation energy...
April 18, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28258928/inhaled-dry-powder-mannitol-in-children-with-cystic-fibrosis-a-randomised-efficacy-and-safety-trial
#14
K De Boeck, E Haarman, J Hull, L C Lands, A Moeller, A Munck, J Riethmüller, H Tiddens, S Volpi, J Leadbetter, B Charlton, A Malfroot
INTRODUCTION: Inhaled mannitol has beneficial effects on lung function, mucociliary clearance, quality of life and sputum properties. This trial examined the efficacy of inhaled mannitol in children with cystic fibrosis (CF). METHODS: The efficacy of inhaled mannitol in children with CF aged 6-17years was assessed in a phase 2, randomised, placebo-controlled crossover study. Subjects were randomly assigned to mannitol 400mg every 12h or matching placebo for 8weeks, followed by an 8week washout and an 8week period with the alternate treatment...
May 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28225274/a-rational-design-of-a-selective-inhibitor-for-kv1-1-channels-prevalent-in-demyelinated-nerves-that-improves-their-impaired-axonal-conduction
#15
Ahmed Al-Sabi, Declan Daly, Patrick Hoefer, Gemma K Kinsella, Charles Metais, Mark Pickering, Caroline Herron, Seshu Kumar Kaza, Kieran Nolan, J Oliver Dolly
K(+) channels containing Kv1.1 α subunits, which become prevalent at internodes in demyelinated axons, may underlie their dysfunctional conduction akin to muscle weakness in multiple sclerosis. Small inhibitors were sought with selectivity for the culpable hyper-polarizing K(+) currents. Modeling of interactions with the extracellular pore in a Kv1.1-deduced structure identified diaryldi(2-pyrrolyl)methane as a suitable scaffold with optimized alkyl ammonium side chains. The resultant synthesized candidate [2,2'-((5,5'(di-p-topyldiaryldi(2-pyrrolyl)methane)bis(2,2'carbonyl)bis(azanediyl)) diethaneamine·2HCl] (8) selectively blocked Kv1...
March 23, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28166462/comparison-of-personal-diesel-and-biodiesel-exhaust-exposures-in-an-underground-mine
#16
Eric A Lutz, Rustin J Reed, Vivien S T Lee, Jefferey L Burgess
This study aimed to compare personal exposures to diesel fuel and a biodiesel blend exhaust in an underground mine. Personal exposure monitoring was performed in a non-operational, hard rock underground mine during use of a load-haul-dump vehicle. Eight-hour time-weighted average (TWA8) exposure concentrations of ultra-low sulfur diesel and 75% biodiesel/25% diesel blend (B75) fuels were compared.  Compared to diesel, use of B75 was associated with relative percent reductions of 22 and 28% in median respirable (r) diesel particulate matter (DPM) and nitrogen dioxide and 25 and 23% increases in median total DPM and nitric oxide TWA8 exposure concentrations, respectively...
July 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28152694/using-a-disease-pathway-management-approach-to-improve-the-quality-of-breast-cancer-care-in-ontario
#17
Jasmin Soobrian, Ashley Tyrrell, Clement Li, Derek Muradali, Margaret F Forbes, Angelika Gollnow, Jillian Ross, Claire Holloway
109 Background: Disease Pathway Management (DPM) is used by Cancer Care Ontario (CCO) to set priorities for cancer control, plan cancer services, and improve the quality of care in Ontario by promoting standardization. The DPM approach applies a framework to examine the performance of the entire system from prevention to end of life care, and to identify any gaps within the system. In 2014, DPM began its breast cancer pathway initiative by mapping the patient journey, depicting evidence-based best practice along the breast cancer care continuum, identifying where further guidance is needed for clinical decision making, and identifying gaps in quality of care and performance measurement indicators...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152692/pathway-map-development-as-an-approach-to-identifying-priority-areas-for-quality-improvement-in-ontario
#18
Jasmin Soobrian, Joan Murphy, Lorraine Elit, Michael F Milosevic, Angelika Gollnow, Jillian Ross, Claire Holloway
108 Background: Disease Pathway Management (DPM) is the unifying approach to the way in which Cancer Care Ontario (CCO) sets priorities for cancer control, plans cancer services and improves the quality of care in Ontario. In 2014 DPM began developing a cervical cancer pathway map (CCPM) to map the patient journey along the cervical cancer care continuum. OBJECTIVE: to report on the CPPM development process as a tool to identify key priorities for cervical cancer management in Ontario...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28147238/endoscopic-evacuation-of-basal-ganglia-hematoma-surgical-technique-outcome-and-learning-curve
#19
Lichao Ma, Yuanzheng Hou, Ruyuan Zhu, Xiaolei Chen
BACKGROUND: Minimally invasive endoscopic hematoma evacuation is a promising treatment option for intracerebral hemorrhage. However, the technique still needs improvement. We report our clinical experience of using this technique to evacuate deep-seated basal ganglia hematomas. METHODS: The frontal approach was used in most patients. The preoperative and postoperative hematoma volumes, Glasgow Coma Scale, hematoma evacuation rate, 30-day mortality, and long-term outcome defined by the modified Rankin Scale were analyzed retrospectively...
May 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28056894/study-protocol-the-norfolk-diabetes-prevention-study-ndps-a-46%C3%A2-month-multi-centre-randomised-controlled-parallel-group-trial-of-a-lifestyle-intervention-with-or-without-additional-support-from-lay-lifestyle-mentors-with-type-2-diabetes-to-prevent-transition
#20
Melanie Pascale, Nikki Murray, Max Bachmann, Garry Barton, Allan Clark, Amanda Howe, Colin Greaves, Mike Sampson
BACKGROUND: This 7 year NIHR programme [2011-2018] tests the primary hypothesis that the NDPS diet and physical activity intervention will reduce the risk of transition to type 2 diabetes (T2DM) in groups at high risk of Type 2 diabetes. The NDPS programme recognizes the need to reduce intervention costs through group delivery and the use of lay mentors with T2DM, the realities of normal primary care, and the complexity of the current glycaemic categorisation of T2DM risk. METHODS: NDPS identifies people at highest risk of T2DM on the databases of 135 general practices in the East of England for further screening with ab fasting plasma glucose and glycosylated haemoglobin [HbA1c]...
January 6, 2017: BMC Public Health
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