keyword
Keywords Ventricular structure-function...

Ventricular structure-function relation

https://read.qxmd.com/read/38490273/patterns-of-atrial-fibrillation-relevant-cardiac-structural-and-functional-changes-predict-functional-and-cognitive-outcomes-in-patients-with-ischemic-stroke-and-atrial-fibrillation
#1
JOURNAL ARTICLE
Jiahuan Guo, Dandan Wang, Jiaokun Jia, Jia Zhang, Yanfang Liu, Jingjing Lu, Ying Tian, Xingquan Zhao
BACKGROUND: Atrial fibrillation (AF) pattern, relevant cardiac changes are important predictors of outcomes in AF, but their impact on patients with ischemic stroke and AF remained unclear. We aimed to explore the impact of AF patterns, cardiac structural and functional markers on long-term functional and cognitive outcomes in ischemic stroke patients with AF. METHODS: Ischemic stroke patients diagnosed with AF were enrolled in this retrospective cohort study. AF pattern was defined by both traditional and novel classification, in which patients were divided into AF diagnosed after stroke (AFDAS) and known before stroke (KAF)...
March 13, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38485036/analysis-and-validation-of-hub-genes-in-neutrophil-extracellular-traps-for-the-long-term-prognosis-of-myocardial-infarction
#2
JOURNAL ARTICLE
Xuan Li, Wenyu Wu, Huan He, Lin Guan, Guancheng Chen, Zhijun Lin, Huan Li, Jialin Jiang, Xin Dong, Zhuoji Guan, Pinliang Chen, Zigang Pan, Weiwei Huang, Runjia Yu, Wenxin Song, Lu Lu, Zhongqi Yang, Zixin Chen, Lingjun Wang, Shaoxiang Xian, Jie Chen
INTRODUCTION: The study focuses on the long-term prognosis of myocardial infarction (MI) influenced by neutrophil extracellular traps (NETs). It also aims to analyze and validate relative hub genes in this process, in order to further explore new therapeutic targets that can improve the prognosis of MI. MATERIALS AND METHODS: We established a MI model in mice by ligating the left anterior descending branch (LAD) and conducted an 8-week continuous observation to study the dynamic changes in the structure and function of the heart in these mice...
March 12, 2024: Gene
https://read.qxmd.com/read/38481714/eligibility-and-potential-benefit-of-transcatheter-edge-to-edge-repair-in-a-contemporary-cohort-with-heart-failure-evidence-from-a-large-integrated-health-care-delivery-system
#3
JOURNAL ARTICLE
Andrew P Ambrosy, Jingrong Yang, Andrew S Tai, Sadia J Dimbil, Elisha A Garcia, Sue Hee Sung, Ankeet S Bhatt, Matthew D Solomon, Ivy A Ku, Jacob M Mishell, Edward J McNulty, Jonathan G Zaroff, Andrew N Rassi, Jeremy Kong, Alan S Go
BACKGROUND: The eligibility and potential benefit of transcatheter edge-to-edge repair (TEER) in addition to guideline-directed medical therapy to treat moderate-severe or severe secondary mitral regurgitation (MR) has not been reported in a contemporary heart failure (HF) population. METHODS: Eligibility for TEER based on Food and Drug Administration (FDA) labeling: (1) HF symptoms, (2) moderate-severe or severe MR, (3) left ventricular ejection fraction (LVEF) 20% to 50%, (4) left ventricular end-systolic dimension 7...
March 2024: Structural heart: the journal of the Heart Team
https://read.qxmd.com/read/38466347/sex-specific-structural-and-functional-cardiac-remodeling-during-healthy-aging-assessed-by-cardiovascular-magnetic-resonance
#4
JOURNAL ARTICLE
Leonhard Grassow, Jan Gröschel, Hadil Saad, Leo Dyke Krüger, Johanna Kuhnt, Maximilian Müller, Thomas Hadler, Edyta Blaszczyk, Jeanette Schulz-Menger
BACKGROUND: Aging as a major non-modifiable cardiac risk factor challenges future cardiovascular medicine and economic demands, which requires further assessments addressing physiological age-associated cardiac changes. OBJECTIVES: Using cardiovascular magnetic resonance (CMR), this study aims to characterize sex-specific ventricular adaptations during healthy aging. METHODS: The population included healthy volunteers who underwent CMR at 1...
March 11, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38464894/association-between-left-ventricular-remodeling-and-lipid-profiles-in-obese-children-an-observational-study
#5
JOURNAL ARTICLE
Ying Tang, Guang-Bin Yang, Jun Chen, Ye Chen, Li-Chun Hua
OBJECTIVE: Childhood obesity has become a prominent issue in the society, which can lead to left ventricular remodeling and severe cardiovascular complications in adulthood. It is beneficial to identify the causes of left ventricular remodeling so that targeted measures can be taken to prevent the cardiovascular disease. Therefore, this study aimed to explore the relationship between left ventricular remodeling and changes in blood lipid indexes in obese children. METHODS: This study was conducted on 40 healthy non-obese children and 140 obese children diagnosed in the pediatric health department of our hospital...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38461325/cardiac-biopsies-reveal-differences-in-transcriptomics-between-left-and-right-ventricle-in-patients-with-or-without-diagnostic-signs-of-heart-failure
#6
JOURNAL ARTICLE
Christoffer Frisk, Sarbashis Das, Maria J Eriksson, Anna Walentinsson, Matthias Corbascio, Camilla Hage, Chanchal Kumar, Mattias Ekström, Eva Maret, Hans Persson, Cecilia Linde, Bengt Persson
New or mild heart failure (HF) is mainly caused by left ventricular dysfunction. We hypothesised that gene expression differ between the left (LV) and right ventricle (RV) and secondly by type of LV dysfunction. We compared gene expression through myocardial biopsies from LV and RV of patients undergoing elective coronary bypass surgery (CABG). Patients were categorised based on LV ejection fraction (EF), diastolic function and NT-proBNP into pEF (preserved; LVEF ≥ 45%), rEF (reduced; LVEF < 45%) or normal LV function...
March 9, 2024: Scientific Reports
https://read.qxmd.com/read/38456848/advanced-maternal-age-alters-cardiac-functional-and-structural-adaptations-to-pregnancy-in-rats
#7
JOURNAL ARTICLE
Amy L Wooldridge, Raven Kirschenman, Floor Spaans, Mazhar Pasha, Sandra T Davidge, Christy-Lynn M Cooke
A significant number of pregnancies occur at advanced maternal age (>35 years), which is a risk factor for pregnancy complications. Healthy pregnancies require massive hemodynamic adaptations, including an increased blood volume and cardiac output. There is growing evidence that these cardiovascular adaptations are impaired with age, however, little is known about maternal cardiac function with advanced age. We hypothesized that cardiac adaptations to pregnancy are impaired with advanced maternal age. Younger (4 months; ~early reproductive maturity in humans) and aged (9 months; ~35 years in humans) pregnant Sprague-Dawley rats were assessed and compared to age-matched non-pregnant controls...
March 8, 2024: American Journal of Physiology. Heart and Circulatory Physiology
https://read.qxmd.com/read/38454596/the-effect-of-long-term-soccer-training-on-left-ventricular-structure-and-function-in-elite-male-youth-soccer-players
#8
JOURNAL ARTICLE
Viswanath B Unnithan, Alexander Beaumont, Thomas Rowland, Keith George, Laura Stewart, Nicholas Sculthorpe, Rachel N Lord, David L Oxborough
AIMS: Cardiac adaptations in elite, male adolescent youth soccer players have been demonstrated in relation to training status. The time course of these adaptations and the delineation of the influence of volatile growth phases from the training effect on these adaptations remain unclear. Consequently, the aims of the study were to evaluate the impact of 3 years of elite-level soccer training on changes in left ventricular (LV) structure and function in a group of highly trained elite youth male soccer players (SP) as they transitioned through the pre-to-adolescent phase of their growth...
March 2024: Scandinavian Journal of Medicine & Science in Sports
https://read.qxmd.com/read/38449779/a-rare-case-report-of-type-1-congenital-disorders-of-glycosylation-with-acute-decompensated-heart-failure-and-the-incidental-discovery-of-congenital-disorders-of-glycosylation-associated-dilated-cardiomyopathy-and-acute-myocarditis
#9
Woo Sze Yang, Suchi Grover, Emma Smith, Joseph B Selvanayagam
BACKGROUND: Congenital disorders of glycosylation (CDG) are rare genetically inherited defects leading to enzyme deficiency or malfunction in the glycosylation pathway. Normal glycosylation is essential to the development of normal cardiac anatomy and function. Congenital disorders of glycosylation-related cardiomyopathy are often the first manifestation detected in early life and may lead to sudden cardiac death. Approximately one-fifth of CDG types are related to cardiac diseases that include cardiomyopathy, rhythm disturbances, pericardial effusions, and structural heart disease...
March 2024: European Heart Journal. Case Reports
https://read.qxmd.com/read/38437242/impact-of-hypertensive-disorders-of-pregnancy-on-offspring-cardiovascular-function-study-from-fetal-life-to-early-childhood
#10
JOURNAL ARTICLE
S Dimopoulou, D Neculcea, I Papastefanou, A Galan, M Androulaki, K H Nicolaides, M Charakida
OBJECTIVE: Epidemiological studies suggest that children following in utero exposure to hypertensive disorders of pregnancy (HDP) may be at increased long term cardiovascular risk. However, data in early childhood are lacking. We aimed to investigate the independent influence of HDP on childhood heart after accounting for differences in childhood risk factor profile. METHODS: We performed detailed cardiovascular assessment in fetuses at mid-gestation and at a median of 2...
March 4, 2024: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38436994/ferumoxytol-enhanced-cardiac-cine-mri-reconstruction-using-a-variable-splitting-spatiotemporal-network
#11
JOURNAL ARTICLE
Chang Gao, Zhengyang Ming, Kim-Lien Nguyen, Jianing Pang, Arash Bedayat, Brian M Dale, Xiaodong Zhong, J Paul Finn
BACKGROUND: Balanced steady-state free precession (bSSFP) imaging is commonly used in cardiac cine MRI but prone to image artifacts. Ferumoxytol-enhanced (FE) gradient echo (GRE) has been proposed as an alternative. Utilizing the abundance of bSSFP images to develop a computationally efficient network that is applicable to FE GRE cine would benefit future network development. PURPOSE: To develop a variable-splitting spatiotemporal network (VSNet) for image reconstruction, trained on bSSFP cine images and applicable to FE GRE cine images...
March 4, 2024: Journal of Magnetic Resonance Imaging: JMRI
https://read.qxmd.com/read/38413438/elevated-itga1-levels-in-type-2-diabetes-implications-for-cardiac-function-impairment
#12
JOURNAL ARTICLE
Mengqi Su, Yilin Hou, Sidong Cai, Wenpeng Li, Yinxia Wei, Run Wang, Min Wu, Mingya Liu, Junlei Chang, Kelaier Yang, Kaihang Yiu, Cong Chen
AIMS/HYPOTHESIS: Type 2 diabetes mellitus is known to contribute to the development of heart failure with preserved ejection fraction (HFpEF). However, identifying HFpEF in individuals with type 2 diabetes early on is often challenging due to a limited array of biomarkers. This study aims to investigate specific biomarkers associated with the progression of HFpEF in individuals with type 2 diabetes, for the purpose of enabling early detection and more effective management strategies. METHODS: Blood samples were collected from individuals with type 2 diabetes, both with and without HFpEF, for proteomic analysis...
February 27, 2024: Diabetologia
https://read.qxmd.com/read/38369940/association-of-echocardiography-related-parameters-with-the-prognosis-of-liver-cirrhosis-a-retrospective-cohort-study
#13
JOURNAL ARTICLE
Weiwei Wang, Liyan Dong, Yue Gao, Fangbo Gao, Zhongchao Wang, Min Ding, Chunru Gu, Zhe Li, Yue Yin, Menghua Zhu, Hongxin Chen, Hongyu Li, Xingshun Qi
BACKGROUND: Cardiac morphology and function, which are conventionally evaluated by echocardiography, are often abnormal in decompensated cirrhosis. We aimed to evaluate the association of echocardiography-related parameters with prognosis in cirrhosis. METHODS: This retrospective study included 104 decompensated cirrhotic patients, in whom cardiac structure and function were measured by echocardiography, including mitral inflow early diastolic velocity/mitral inflow late diastolic velocity (E/A), left atrium diameter, left ventricular end-diastolic dimension, interventricular septal thickness, left ventricular posterior wall thickness, right atrial transverse diameter, right atrial longitudinal diameter, right ventricular dimension (RVD), stroke volume, cardiac output, left ventricular ejection fraction, and fractional shortening...
February 19, 2024: Current Medical Research and Opinion
https://read.qxmd.com/read/38365103/increased-grey-matter-volumes-in-the-temporal-lobe-and-its-relationship-with-cognitive-functioning-in-euthymic-patients-with-bipolar-disorder
#14
JOURNAL ARTICLE
D Porta-Casteràs, M Vicent-Gil, M Serra-Blasco, G Navarra-Ventura, B Solé, L Montejo, C Torrent, A Martinez-Aran, V De la Peña-Arteaga, D Palao, E Vieta, N Cardoner, M Cano
BACKGROUND: Bipolar disorder (BD) is characterized by episodic mood dysregulation, although a significant portion of patients suffer persistent cognitive impairment during euthymia. Previous magnetic resonance imaging (MRI) research suggests BD patients may have accelerated brain aging, observed as lower grey matter volumes. How these neurostructural alterations are related to the cognitive profile of BD is unclear. METHODS: We aim to explore this relationship in euthymic BD patients with multimodal structural neuroimaging...
February 14, 2024: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://read.qxmd.com/read/38360102/long-term-changes-in-cardiac-remodelling-in-prevalent-kidney-graft-recipients
#15
JOURNAL ARTICLE
V Panisset, N Girerd, E Bozec, Z Lamiral, Q d'Herve, L Frimat, S Girerd
BACKGROUND: Approximately 15% of kidney transplant (KT) recipients develop de novo heart failure after KT. There are scarce data reporting the long-term changes in cardiac structure and function among KT recipients. Despite the improvement in renal function, transplant-related complications as well as immunosuppressive therapy could have an impact on cardiac remodelling during follow-up. We aimed to describe the long-term changes in echocardiographic parameters in prevalent KT recipients and identify the clinical and laboratory factors associated with these changes...
February 13, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38358359/amphiregulin-improves-ventricular-remodeling-after-myocardial-infarction-by-modulating-autophagy-and-apoptosis
#16
JOURNAL ARTICLE
Nana Li, Ni Xia, Junyi He, Meilin Liu, Muyang Gu, Yuzhi Lu, Haoyi Yang, Zhiheng Hao, Lingfeng Zha, Xuhong Wang, Weimin Wang, Desheng Hu, Jiong Hu, Xiang Cheng
Myocardial infarction (MI) is defined as sudden ischemic death of myocardial tissue. Amphiregulin (Areg) regulates cell survival and is crucial for the healing of tissues after damage. However, the functions and mechanisms of Areg after MI remain unclear. Here, we aimed to investigate Areg's impact on myocardial remodeling. Mice model of MI was constructed and Areg-/- mice were used. Expression of Areg was analyzed using western blotting, RT-qPCR, flow cytometry, and immunofluorescence staining. Echocardiographic analysis, Masson's trichrome, and triphenyltetrazolium chloride staining were used to assess cardiac function and structure...
February 29, 2024: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://read.qxmd.com/read/38354974/a-treadmill-exercise-reduced-cardiac-fibrosis-inflammation-and-vulnerability-to-ischemia-reperfusion-in-rat-pristane-induced-arthritis
#17
JOURNAL ARTICLE
C Peyronnel, J Kessler, S Devaux, C Houdayer, M Tournier, M Chouk, D Wendling, H Martin, P Totoson, C Demougeot
AIMS: To explore cardiac structural and functional parameters and myocardial sensitivity to ischemia in a rat model of chronic arthritis, pristane-induced arthritis (PIA), and to investigate the effects of a running exercise protocol on cardiac disorders related to rheumatoid arthritis (RA). MAIN METHODS: 3 groups of male Dark Agouti rats were formed: Controls, PIA and PIA-Exercise. The PIA-Exercise group was subjected to an individualized treadmill running protocol during the remission phase...
February 12, 2024: Life Sciences
https://read.qxmd.com/read/38337590/mitral-annular-calcification-related-valvular-disease-a-challenging-entity
#18
REVIEW
Abdulrahman S Museedi, Thierry H Le Jemtel
Mitral valve annular calcification-related valvular disease is increasingly common due to the rising prevalence of age-related mitral annular calcifications. Mitral annular calcification alters the structure and function of the mitral valve annulus, which in turn causes mitral valve regurgitation, stenosis, or both. As it frequently coexists with comorbid conditions and overlapping symptoms, mitral annular calcification-related valvular disease poses significant diagnostic and therapeutic challenges. For instance, left ventricular diastolic dysfunction hinders the assessment of mitral valvular disease...
February 3, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38337535/advances-in-multi-modality-imaging-in-hypertrophic-cardiomyopathy
#19
REVIEW
Fraser C Goldie, Matthew M Y Lee, Caroline J Coats, Sabrina Nordin
Hypertrophic cardiomyopathy (HCM) is characterized by abnormal growth of the myocardium with myofilament disarray and myocardial hyper-contractility, leading to left ventricular hypertrophy and fibrosis. Where culprit genes are identified, they typically relate to cardiomyocyte sarcomere structure and function. Multi-modality imaging plays a crucial role in the diagnosis, monitoring, and risk stratification of HCM, as well as in screening those at risk. Following the recent publication of the first European Society of Cardiology (ESC) cardiomyopathy guidelines, we build on previous reviews and explore the roles of electrocardiography, echocardiography, cardiac magnetic resonance (CMR), cardiac computed tomography (CT), and nuclear imaging...
February 1, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38315669/a-deep-patient-similarity-learning-framework-for-the-assessment-of-diastolic-dysfunction-in-elderly-patients
#20
JOURNAL ARTICLE
Rohan Shah, Marton Tokodi, Ankush Jamthikar, Sabha Bhatti, Ehimare Akhabue, Grace Casaclang-Verzosa, Naveena Yanamala, Partho P Sengupta
BACKGROUND AND AIMS: Age-related changes in cardiac structure and function are well recognized and make the clinical determination of abnormal LV diastolic function (LVDD) particularly challenging in the elderly. We investigated whether a deep neural network (DeepNN) model[70] of LVDD, previously validated in a younger cohort, can be implemented in an older population to predict incident heart failure (HF). METHODS: A previously developed DeepNN was tested on 5,596 older participants (66-90 years; 57% female; 20% black) from the Atherosclerosis Risk in Communities study...
February 5, 2024: European Heart Journal Cardiovascular Imaging
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