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https://www.readbyqxmd.com/read/28432004/impact-of-right-ventricular-side-branch-occlusion-during-percutaneous-coronary-intervention-of-chronic-total-occlusions-on-right-ventricular-function
#1
Pepijn A van Diemen, Wynand J Stuijfzand, Stefan P Biesbroek, Pieter G Raijmakers, Roel S Driessen, Stefan P Schumacher, Alexander Nap, Albert C van Rossum, Niels van Royen, Robin Nijveldt, Paul Knaapen
OBJECTIVE: To determine the impact of right ventricular side branch (RVB) occlusion, during percutaneous coronary interventions (PCIs) of chronic total occlusions (CTOs) of the right coronary artery (RCA), on right ventricular (RV) function. BACKGROUND: Developments in PCI techniques have expanded PCI CTO feasibility. However, the utilization of dissection and reentry techniques and extensive stent implantation increases the risk of coronary side branch occlusion...
April 11, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28431861/cardiac-computed-tomography-derived-myocardial-mass-at-risk-using-the-voronoi-based-segmentation-algorithm-a-histological-validation-study
#2
Seiko Ide, Satoru Sumitsuji, Osamu Yamaguchi, Yasushi Sakata
BACKGROUND: Myocardial mass at risk (MMAR) is an important predictor of adverse cardiac events in patients with ischemic heart disease. This study aims to validate the accuracy of MMAR calculated from cardiac computed tomography (CCT) data using the Voronoi-based segmentation algorithm in comparison with actual MMAR measured on ex-vivo swine hearts prepared by injecting a dye into the coronary arteries. METHODS: Fifteen extracted swine hearts had India ink injected into one of the major coronary arteries...
April 18, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28426162/motion-corrected-simultaneous-cardiac-positron-emission-tomography-and-coronary-mr-angiography-with-high-acquisition-efficiency
#3
Camila Munoz, Radhouene Neji, Gastão Cruz, Andrew Mallia, Sami Jeljeli, Andrew J Reader, Rene M Botnar, Claudia Prieto
PURPOSE: Develop a framework for efficient free-breathing simultaneous whole-heart coronary magnetic resonance angiography (CMRA) and cardiac positron emission tomography (PET) on a 3 Tesla PET-MR system. METHODS: An acquisition that enables nonrigid motion correction of both CMRA and PET has been developed. The proposed method estimates translational motion from low-resolution 2D MR image navigators acquired at each heartbeat and 3D nonrigid respiratory motion between different respiratory bins from the CMRA data itself...
April 20, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28420590/volume-and-dimensions-of-angiographically-normal-coronary-arteries-assessed-by-multidetector-computed-tomography
#4
Samuel Kiil Sørensen, Jørgen Tobias Kühl, Andreas Fuchs, Jakob Boesgaard Norsk, Lars Valeur Køber, Børge Grønne Nordestgaard, Klaus Fuglsang Kofoed
BACKGROUND: The objective of this study was to determine normal values for coronary artery volume (CAV) and individual vasculature and segment dimensions. METHODS: We examined 200 healthy volunteers with an Agatston score of 0 and a normal, high quality coronary CTA. Using 320 slice multidetector row CT and designated vessel tracing software with border detection algorithm, the main coronary arteries and branches were delineated and total and segmental dimensions calculated...
April 4, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28414671/three-s-a-crowd-an-extremely-rare-case-of-cor-triatriatum-dexter
#5
A Elagizi, R Marvin, G O'Bryan, V Vyas, L Arcement
INTRODUCTION: Cor triatriatum is a congenital cardiac anomaly in which the left (sinister) or right (dexter) atrium is divided into two compartments by residual embryonic tissue, resulting in a tri-atrial heart. As cor triatriatum dextrum can present clinically in various ways and have multiple associated cardiac anomalies, this report attempts to contribute to what is known about this exceedingly rare disorder. CASE: A 40 year old Hispanic man with a medical history of gastritis presented with complaints of palpitations, dizziness and bilateral lower extremity edema...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28414417/graphene-nanoprobes-for-real-time-monitoring-of-isothermal-nucleic-acid-amplification
#6
Fan Li, Xiaoguo Liu, Bin Zhao, Juan Yan, Qian Li, Ali Aldalbahi, Jiye Shi, Shiping Song, Chunhai Fan, Lihua Wang
Isothermal amplification is an efficient way to amplify DNA with high accuracy, however, the real-time monitoring for quantification analysis mostly relied on expensive and precisely designed probes. In the present study, Graphene oxide (GO)-based nano probe was used to real-time monitor the isothermal amplification process. The interaction between GO and different DNA structures was systematically investigated, including single-stranded DNA (ssDNA), double-stranded DNA (dsDNA), DNA 3-helix, and long rolling circle amplification (RCA) and hybridization chain reaction (HCR) products, which existed in one-, two- and three-dimensional structures...
April 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28407129/a-noninferiority-trial-comparing-a-heparin-grafted-membrane-plus-citrate-containing-dialysate-versus-regional-citrate-anticoagulation-results-of-the-cited-study
#7
Björn Meijers, Christoph Metalidis, Thomas Vanhove, Ruben Poesen, Dirk Kuypers, Pieter Evenepoel
Background.: Anticoagulation is a prerequisite for successful haemodialysis. Heparin and low-molecular weight heparins are routinely used despite increased bleeding risk. Regional citrate anticoagulation (RCA) is efficacious, but is laborious and may induce metabolic disturbances. Heparin-grafted membranes are less efficacious. It is not known whether combining citrate-containing dialysate and a heparin-grafted membrane is a valid anticoagulation strategy. Methods.: We performed a randomized crossover noninferiority trial, with a prespecified noninferiority threshold of 10% in maintenance dialysis patients ( n  = 25)...
April 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28400923/significance-of-inferior-wall-ischemia-in-non-dominant-right-coronary-artery-anatomy
#8
Ali Osama Malik, Oliver Abela, Subodh Devabhaktuni, Arhama Aftab Malik, Gayle Allenback, Chowdhury H Ahsan, Sanjay Malhotra, Jimmy Diep
AIM: To investigate the relationship of inferior wall ischemia on myocardial perfusion imaging in patients with non-dominant right coronary artery anatomy. METHODS: This was a retrospective observational analysis of consecutive patients who presented to the emergency department with primary complaint of chest pain. Only patients who underwent single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) were included. Patients who showed a reversible defect on SPECT MPI and had coronary angiography during the same hospitalization was analyzed...
March 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28392779/complementary-metaproteomic-approaches-to-assess-the-bacterioplankton-response-toward-a-phytoplankton-spring-bloom-in-the-southern-north-sea
#9
Lars Wöhlbrand, Bernd Wemheuer, Christoph Feenders, Hanna S Ruppersberg, Christina Hinrichs, Bernd Blasius, Rolf Daniel, Ralf Rabus
Annually recurring phytoplankton spring blooms are characteristic of temperate coastal shelf seas. During these blooms, environmental conditions, including nutrient availability, differ considerably from non-bloom conditions, affecting the entire ecosystem including the bacterioplankton. Accordingly, the emerging ecological niches during bloom transition are occupied by different bacterial populations, with Roseobacter RCA cluster and SAR92 clade members exhibiting high metabolic activity during bloom events...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28381215/a-case-of-successful-reperfusion-through-a-combination-of-intracoronary-thrombolysis-and-aspiration-thrombectomy-in-st-segment-elevation-myocardial-infarction-associated-with-an-ectatic-coronary-artery
#10
Yonggu Lee, Eunjin Kim, Bae Keun Kim, Jeong-Hun Shin
BACKGROUND: Large thrombus burdens in ectatic coronary arteries that remain after aspiration thrombectomy can negatively impact outcomes following percutaneous coronary interventions in patients with acute myocardial infarction. CASE PRESENTATION: A 53-year-old man presented with ST-segment elevation myocardial infarction (STEMI). Coronary angiography revealed an ectatic right coronary artery (RCA) that was completely occluded in the mid portion by a large amount of thrombus...
April 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28379404/a-prospective-study-of-external-stenting-of-saphenous-vein-grafts-to-the-right-coronary-artery-the-vest-ii-study
#11
David P Taggart, Sanaz Amin, Jasmina Djordjevic, Evangelos K Oikonomou, Sheena Thomas, Anna-Maria Kampoli, Nikant Sabharwal, Charalambos Antoniades, George Krasopoulos
OBJECTIVES: External stents significantly reduce intimal hyperplasia and improve lumen uniformity and flow pattern in saphenous vein grafts (SVG) 1 year after coronary artery bypass grafting. However, recent studies have shown that at 1 year there is a lower patency of externally stented SVG to the right coronary artery (RCA) (55-60%) when compared to the left sided coronary arteries (85-90%). In the current study, we investigated whether avoidance of both fixation of the external stent to the anastomoses and the use of metal clips to ligate SVG side branches would improve the early patency of externally stented SVG to the RCA...
May 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28373781/the-prevalence-of-coronary-artery-anomalies-in-qassim-province-detected-by-cardiac-computed-tomography-angiography
#12
Osama A Smettei, Sawsan Sayed, Rami M Abazid
BACKGROUND: Coronary artery anomalies (CAAs) affect about 1% of the general population based on invasive coronary angiography (ICA) data, computed tomography angiography (CTA) enables better visualization of the origin, course, relation to the adjacent structures, and termination of CAAs compared to ICA. OBJECTIVE: The aim of our work is to estimate the frequency of CAAs in Qassim province among patients underwent cardiac CTA at Prince Sultan Cardiac Center. METHODS: Retrospective analysis of the CTA data of 2235 patients between 2009 and 2015...
April 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28372501/hyperlactatemia-predicts-citrate-intolerance-with-regional-citrate-anticoagulation-during-continuous-renal-replacement-therapy
#13
Jia-Neng Tan, Sabrina Wong Peixin Haroon, Amartya Mukhopadhyay, Titus Lau, Tanusya M Murali, Jason Phua, Zong-Yao Tan, Nicholas Lee, Horng-Ruey Chua
PURPOSE: We aim to determine whether hyperlactatemia, which suggests multi-organ dysfunction and impaired organic substrate metabolism, may predict intolerance to regional citrate anticoagulation (RCA) during continuous venovenous hemofiltration (CVVH). METHODS: We performed a single-center, retrospective observational study in critically ill patients with acute kidney injury or end-stage renal disease and evaluated the association of peak serum lactate levels with citrate intolerance (CI) during the initial 72 hours of RCA-CVVH, defined by serum total-to-ionized calcium >2...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28370773/a-dnazyme-feedback-amplification-strategy-for-biosensing
#14
Meng Liu, Qiang Zhang, Dingran Chang, Jimmy Gu, John D Brennan, Yingfu Li
We report a signal amplification strategy termed DNAzyme feedback amplification (DFA) that takes advantage of rolling-circle amplification (RCA) and an RNA-cleaving DNAzyme (RCD). DFA employs two specially programmed DNA complexes, one composed of a primer and a circular template containing the antisense sequence of an RCD, and the other composed of the same circular template and an RNA-containing substrate for the RCD. RCA is initiated at the first complex to produce RCD elements that go on to cleave the substrate in the second complex...
March 28, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28366607/influence-about-the-flow-of-distal-branch-after-intervention-of-the-right-coronary-artery-chronic-total-occlusion
#15
Hsiu-Yu Fang, Chiung-Jen Wu, Chih-Yuan Fang, Wei-Chieh Lee
OBJECTIVE: Limited data are available for the clinical outcomes after the recanalization of right coronary artery (RCA) chronic total occlusion (CTO). The study aims to assess the clinical outcomes in the antegrade flow of the distal branch after successful RCA CTO percutaneous coronary intervention (PCI). METHODS: Between January 2002 and December 2012, 538 patients who underwent RCA CTO PCI were enrolled. The clinical outcomes as myocardial infarction (MI), target vessel revascularization, cardiac death, major adverse cardiac events, and all-cause mortality, were compared to the antegrade flow of distal branch after successful RCA CTO PCI...
March 22, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28359485/giant-coronary-artery-aneurysm-in-a-middle-aged-woman
#16
Akriti Naraen, Pramod Reddy, Chiara Notarstefano, Manoj Kudavali
Giant coronary artery aneurysm (CAA) is a rare clinicopathologic entity, and there is a dearth of information regarding presentation, diagnosis, and subsequent management. We present a case of a giant aneurysm of the proximal right coronary artery (RCA) that was 1.5 × 1.5 cm with direct communication between the aneurysmal cavity and the aortic sinus. The deficit in the RCA ostium was closed with a patch of bovine pericardium. The distal communication of the aneurysm to the mid-RCA was clearly delineated and tied off...
April 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28358682/curvilinear-3-d-imaging-using-row-column-addressed-2-d-arrays-with-a-diverging-lens-feasibility-study
#17
Hamed Bouzari, Mathias Engholm, Christopher Beers, Matthias B Stuart, Svetoslav I Nikolov, Erik V Thomsen, Jorgen A Jensen
Constructing a double-curved row-columnaddressed (RCA) 2-D array or applying a diverging lens over the flat RCA 2-D array can extend the imaging field-of-view (FOV) to a curvilinear volume without increasing the aperture size, which is necessary for applications such as abdominal and cardiac imaging. Extended FOV and low channel count of double-curved RCA 2-D arrays make 3-D imaging possible with equipment in the price range of conventional 2-D imaging. This study proposes a delay-and-sum beamformation scheme specific to double-curved RCA 2-D arrays and validates its focusing ability based on simulations...
March 24, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28343170/mirnas-single-nucleotide-polymorphisms-snps-and-age-related-macular-degeneration-amd
#18
REVIEW
John Paul SanGiovanni, Peter M SanGiovanni, Przemysław Sapieha, Vincent De Guire
Advanced age-related macular degeneration (AAMD) is a complex sight-threating disease of public health significance. Micro RNAs (miRNAs) have been proposed as biomarkers for AAMD. The presence of certain single nucleotide polymorphisms (SNPs) may influence the explanatory value of these biomarkers. Here we present findings from an integrated approach used to determine whether AAMD-associated SNPs have the capacity to influence miRNA-mRNA pairing and, if so, to what extent such pairing may be manifested in a discrete AAMD transcriptome...
May 1, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28335983/ideal-guiding-catheter-position-during-bilaterally-engaged-percutaneous-coronary-intervention
#19
Kensuke Yokoi, Masahiko Hara, Yasunori Ueda, Satoru Sumitsuji, Masaki Awata, Youssef K Salah, Daijiro Kabata, Ayumi Shintani, Yasushi Sakata
Using a novel combined angiography computed tomography (CT) system, we evaluated the impact of the intra-aortic root position of a right coronary artery (RCA) catheter on its coaxiality. We retrospectively enrolled 19 patients who underwent CT scans during bilaterally engaged percutaneous coronary intervention. Coaxiality was defined as the angle between the RCA and the RCA catheter. The coaxiality was better when the RCA catheter was placed anterior to the left main coronary artery catheter (median 27.0° vs 53...
March 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28335318/a-label-free-and-sensitive-fluorescent-qualitative-assay-for-bisphenol-a-based-on-rolling-circle-amplification-exonuclease-iii-combined-cascade-amplification
#20
Xia Li, Juan Song, Qing-Wang Xue, Fu-Heng You, Xia Lu, Yan-Cong Kong, Shu-Yi Ma, Wei Jiang, Chen-Zhong Li
Bisphenol A (BPA) detection in drinking water and food packaging materials has attracted much attention since the discovery that BPA can interfere with normal physiological processes and cause adverse health effects. Here, we constructed a label-free aptamer fluorescent assay for selective and sensitive detection of BPA based on the rolling circle amplification (RCA)/Exonuclease III (Exo III)-combined cascade amplification strategy. First, the duplex DNA probe (RP) with anti-BPA aptamer and trigger sequence was designed for BPA recognition and signal amplification...
October 21, 2016: Nanomaterials
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