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https://www.readbyqxmd.com/read/29792999/does-solid-fusion-eliminate-rod-fracture-after-pedicle-subtraction-osteotomy-in-ankylosing-spondylitis-related-thoracolumbar-kyphosis
#1
Shi-Zhou Zhao, Bang-Ping Qian, Mu Qiao, Jun Jiang, Yong Qiu
BACKGROUND CONTEXT: Rod fracture (RF) has a negative impact on the surgical outcome of ankylosing spondylitis (AS) patients following lumbar pedicle subtraction osteotomy (PSO). However, there is a paucity of published studies analyzing the risk factors for RF in PSO-treated AS patients with thoracolumbar kyphosis. PURPOSE: To investigate the risk factors for RF after PSO for thoracolumbar kyphosis secondary to AS. STUDY DESIGN/SETTING: Retrospective single-center study...
May 21, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29788926/correlation-of-increased-corrected-timi-frame-counts-and-the-topographical-extent-of-isolated-coronary-artery-ectasia
#2
Wei Wu, Shuyang Zhang, Yuchao Guo, Ruifeng Liu, Zhujun Shen, Xueqing Zhu, Zhenyu Liu
BACKGROUND: The precise relationship between increased thrombolysis in myocardial infarction (TIMI) frame counts and the topographical extent of isolated coronary artery ectasia (CAE) has not been fully explained. New parameters of linear dimension (LD) and the estimated ectatic area (EEA) together with the diameter and ectasia ratio may be associated with the corrected TIMI frame count (CTFC) in isolated CAE patients. METHODS: The topographical parameters of ectatic coronary arteries and/or segments of 77 isolated CAE patients were consecutively studied...
May 22, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29788715/versatile-electrochemiluminescence-assays-for-pedv-antibody-based-on-rolling-circle-amplification-and-ru-dna-nanotags
#3
Jing Ma, Long Wu, Zhonghua Li, Zhicheng Lu, Wenmin Yin, Axiu Nie, Fan Ding, Biru Wang, Heyou Han
The sensitive and accurate detection methods for PEDV antibody have practical significance for the prevention and treatment of PEDV. In this work, a new multiple pathways signal amplification method was proposed to construct a sensitive electroluminescence (ECL) platform for the detection of PEDV antibody. By using Au NPs modified graphene nanosheet (Au-GN) as substrate, antibody-antigen reaction as recognition unit, rolling circle amplification (RCA) for signal enhancement, and assembled cascade Ru-DNA nanotags as signal label, the proposed platform behaved good specificity and sensitivity...
May 23, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29788153/aggregate-analysis-of-sentinel-events-as-a-strategic-tool-in-safety-management-can-contribute-to-the-improvement-of-healthcare-safety
#4
Angelo B Hooker, Anouk Etman, Matthijs Westra, Wouter J Van der Kam
Objective: To examine if clustering of root causes of sentinel events (SEs) can contribute to organisational improvement of healthcare and patient safety by providing insight into organisational risk factors, patterns and trends. Design: Retrospective, cross-sectional review of SEs from a hospital database reported to the Board of directors in 2016. Setting: A regional teaching hospital in the Netherlands. Intervention(s): Clustering of characteristics and variables of SEs to establish vulnerabilities and patterns of failure factors of the organisation...
May 19, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29780643/late-diagnosis-of-anomalous-aortic-origin-of-a-coronary-artery-from-the-inappropriate-sinus-of-valsalva-during-investigation-of-chest-pain
#5
Brunna Priscylla Américo Carvalho, Marcio Antônio Dos Santos, Wilson Pedro Guimarães Neto, Júlio César Queiroz De França, Márcio Rogério de Souza Braite, Rodrigo Bottura De Araújo, Isabella Gomes Carvalho, Moacir Fernandes de Godoy
In this work are reported two cases of anomalous aortic origin of a coronary artery (AAOCA), with the left main coronary artery (LMCA) arising at the right sinus of Valsalva in a 77-year-old woman and in a 79-year-old man submitted to angiography after positive ischemic tests. The origin of the LMCA or the left descendant artery (LDA) from the right sinus of Valsalva has a prevalence of 0.2%, the origin of the circumflex artery (CXA) from the right sinus 0.5%, and the origin of the right coronary artery (RCA) from the left sinus of Valsalva has a prevalence of 0...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29761325/correction-to-rapid-identification-of-seven-waterborne-exophiala-species-by-rca-dna-padlock-probes
#6
M J Najafzadeh, V A Vicente, Peiying Feng, A Naseri, Jiufeng Sun, A Rezaei-Matehkolaei, G S de Hoog
The Editorial Office of Mycopathologia reports that several paragraphs of Najafzadeh et al. were transcribed with only minor edits from previously published material by Najafzadeh M.J.
May 14, 2018: Mycopathologia
https://www.readbyqxmd.com/read/29759708/intra-atrial-right-coronary-artery-and-its-ablation-implications
#7
Balaji Krishnan, Caroline Cross, Richard Dykoski, David G Benditt, Mackenzie Mbai, Edward McFalls, Jian-Ming Li, Stefan Bertog, Venkatakrishna N Tholakanahalli
OBJECTIVES: The study examined the frequency in which a right coronary artery (RCA) anomaly resulting in intra-atrialization of the vessel might increase risk of RCA damage during routine radiofrequency ablation in the right atrium even with low power or temperature. BACKGROUND: Right coronary artery (RCA) injury with endocardial RF ablation of the right atrium is a rare complication. METHODS: This prospective observational study comprised an analysis of coronary artery anatomies in 331 patients who underwent autopsies at our institution from 2005 to 2014...
September 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29758950/simulated-medication-errors-a-means-of-evaluating-healthcare-professionals-knowledge-and-understanding-of-medication-safety
#8
Hesty Utami Ramadaniati, Jeffery David Hughes, Ya Ping Lee, Lynne Maree Emmerton
OBJECTIVE: To determine multi-disciplinary perceptions of the clinical significance of medication errors (MEs), the responsible health professional(s), the contributing factors and potential preventive strategies. METHODS: The five simulated ME cases represented errors from five wards at a children's hospital in Australia. Pre-determined answers for each case were developed through consensus among the researchers. The root cause analysis (RCA) was undertaken via a questionnaire disseminated to physicians, nurses and pharmacists at the study hospital to seek their opinions on the ME cases...
May 9, 2018: International Journal of Risk & Safety in Medicine
https://www.readbyqxmd.com/read/29755631/anomalous-coronary-artery-from-the-opposite-sinus-acaos-technical-challenges-during-percutaneous-coronary-intervention
#9
Santosh Kumar Sinha, Mahmodula Razi, Anupam Mahrotra, Puneet Aggarwal, Anupam Singh, Lokendra Rekwal, Sunil Tripathi, Nishant Kumar Abhishekh, Vinay Krishna
Anomalies of the coronary arteries are reported in 1-2% of patients among diagnostic angiogram. Ectopic origin of right coronary artery (RCA) from opposite sinus is one of the most common and they are mainly benign, but at times may be malignant. We report a case of a 69-year-old male who underwent early invasive percutaneous coronary intervention for non-ST-segment elevation myocardial infarction (NSTEMI) where RCA arising from left sinus at the root of left main artery was culprit and various technical challenges were encountered while intervening in form of cannulation to tracking of hardwares...
April 2018: Cardiology Research
https://www.readbyqxmd.com/read/29754161/motion-corrected-whole-heart-pet-mr-for-the-simultaneous-visualisation-of-coronary-artery-integrity-and-myocardial-viability-an-initial-clinical-validation
#10
Camila Munoz, Karl P Kunze, Radhouene Neji, Teresa Vitadello, Christoph Rischpler, René M Botnar, Stephan G Nekolla, Claudia Prieto
PURPOSE: Cardiac PET-MR has shown potential for the comprehensive assessment of coronary heart disease. However, image degradation due to physiological motion remains a challenge that could hinder the adoption of this technology in clinical practice. The purpose of this study was to validate a recently proposed respiratory motion-corrected PET-MR framework for the simultaneous visualisation of myocardial viability (18 F-FDG PET) and coronary artery anatomy (coronary MR angiography, CMRA) in patients with chronic total occlusion (CTO)...
May 12, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29752496/what-are-the-conditions-of-riparian-ecosystems-identifying-impaired-floodplain-ecosystems-across-the-western-u-s-using-the-riparian-condition-assessment-rca-tool
#11
William W Macfarlane, Jordan T Gilbert, Joshua D Gilbert, William C Saunders, Nate Hough-Snee, Chalese Hafen, Joseph M Wheaton, Stephen N Bennett
Environmental stressors associated with human land and water-use activities have degraded many riparian ecosystems across the western United States. These stressors include (i) the widespread expansion of invasive plant species that displace native vegetation and exacerbate streamflow and sediment regime alteration; (ii) agricultural and urban development in valley bottoms that decouple streams and rivers from their floodplains and reduce instream wood recruitment and retention; and (iii) flow modification that reduces water quantity and quality, degrading aquatic habitats...
May 11, 2018: Environmental Management
https://www.readbyqxmd.com/read/29745198/-response-and-adaptation-of-photosynthesis-of-cucumber-seedlings-to-high-temperature-stress
#12
Sheng Nan Sun, Qiang Wang, Chen Chen Sun, Feng Jiao Liu, Huan Gai Bi, Xi Zhen Ai
Cucumber seedlings (Cucumis sativus Jinyou 35) were used to study the effects of high temperature (HT: 42 ℃/32 ℃) and sub-high temperature (SHT: 35 ℃/25 ℃) on its photosynthesis and growth. The results showed that the growth of cucumber seedlings was dramatically inhibited by the high and sub-high temperature stresses. The photosynthetic rate (Pn ) was gradually reduced, while intercellular CO2 concentration (Ci ) was increased as heat stress lasted. Under heat stress, stomatal conductance (gs ), transpiration rate (Tr ), photorespiration rate (Pr ) and dark respiration rate (Dr ) showed a trend from rise to decline in cucumber seedlings, which implied that heat-induced decline of photosynthesis was mainly due to non-stomatal limitation...
May 18, 2017: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29744224/right-coronary-artery-originating-from-the-left-do-not-miss-the-diagnosis
#13
Sedat Türkoğlu, Serkan Ünlü, Gülten Aydoğdu Taçoy, Murat Özdemir
Objective: Left circumflex (LCx) artery originating from the right coronary arterial (RCA) system has been reported as the most common form of anomalous origination of a coronary artery from the opposite sinus (ACAOS). However, some studies claim that RCA originating from the left coronary sinus (LCS) is the most frequent form. The aim of this study was to determine the most common type of ACAOS in a single center. Materials and Methods: The database of the catheterization laboratory was retrospectively searched...
2018: Cardiology Research and Practice
https://www.readbyqxmd.com/read/29737362/-regional-citrate-anticoagulation-in-renal-replacement-therapy-in-the-intensive-care-station-recommendations-from-the-renal-section-of-the-dgiin-%C3%A3-giain-and-divi
#14
REVIEW
M Schmitz, M Joannidis, D Czock, S John, A Jörres, S J Klein, M Oppert, V Schwenger, J Kielstein, A Zarbock, D Kindgen-Milles, C Willam
BACKGROUND: Regional citrate anticoagulation (RCA) in continuous renal replacement therapy can effectively anticoagulate dialysis circuits without having adverse effects on systemic heparin application. In particular, in continuous renal replacement therapy RCA is well established and represents a safe procedure with longer filter lifetimes and fewer bleeding complications. OBJECTIVES: To provide guidance on the indications, advantages and disadvantages, and use of RCA, current recommendations from the renal section of the DGIIN (Deutschen Gesellschaft für Internistische Intensivmedizin und Notfallmedizin), ÖGIAIN (Österreichischen Gesellschaft für Internistische und Allgemeine Intensivmedizin und Notfallmedizin) and DIVI (Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin) are stated...
May 8, 2018: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/29736852/thoracic-involvement-in-erdheim-chester-disease-computed-tomography-imaging-findings-and-their-association-with-the-braf-v600e-mutation
#15
S Mojdeh Mirmomen, Arlene Sirajuddin, Moozhan Nikpanah, Rolf Symons, Anna K Paschall, Ioannis Papageorgiou, William A Gahl, Kevin O'Brien, Juvianee I Estrada-Veras, Ashkan A Malayeri
OBJECTIVES: To investigate the computed tomography (CT) thoracic findings in Erdheim-Chester disease (ECD) and evaluate the association of these findings with the BRAFV600E mutation. METHODS: This was a prospective study of patients with ECD (n=61, men=46) who underwent thoracic CT imaging. CT examinations were independently interpreted by two experienced radiologists. Association of imaging findings with BRAFV600E was achieved via the Chi-square or Fisher's exact test and odds ratios (OR) with 95% confidence intervals (CI), as appropriate...
May 7, 2018: European Radiology
https://www.readbyqxmd.com/read/29729845/plan-optimization-for-mediastinal-radiotherapy-estimation-of-coronary-arteries-motion-with-ecg-gated-cardiac-imaging-and-creation-of-compensatory-expansion-margins
#16
Mario Levis, Viola De Luca, Christian Fiandra, Simona Veglia, Antonella Fava, Marco Gatti, Mauro Giorgi, Sara Bartoncini, Federica Cadoni, Domenica Garabello, Riccardo Ragona, Andrea Riccardo Filippi, Umberto Ricardi
BACKGROUND AND PURPOSE: Inadvertent heart and coronary arteries (CA) irradiation may increase the risk of coronary artery disease (CAD) in patients receiving thoracic irradiation. To date, the entity of cardiac-related CA displacement and the possible margins to be used for planning organs at risk volume (PRV) have been poorly described. Aim of this study was to quantify CA displacement and to estimate PRV through the use of ECG-gated computed tomography (CT) scans. MATERIAL AND METHODS: Eight patients received an ECG-gated intravenous contrast enhanced CT for non-cancer related reasons...
May 2, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29721644/morphology-oriented-epigenetic-research
#17
REVIEW
Sohei Kitazawa, Ryuma Haraguchi, Riko Kitazawa
Cytosine methylation plays a major role in the regulation of sequential and tissue-specific expression of genes. De novo aberrant DNA methylation and demethylation are also crucial processes in tumorigenesis and tumor progression. The mechanisms of how and when such aberrant methylation and demethylation occur in tumor cells are still obscure, however. To evaluate subtle epigenetic alteration among minor subclonal populations, morphology-oriented epigenetic analysis is requisite, especially where heterogeneity and flexibility are as notable as in the process of cancer progression and cellular differentiation at critical stages...
May 2, 2018: Histochemistry and Cell Biology
https://www.readbyqxmd.com/read/29721433/lectin-binding-patterns-and-immunohistochemical-antigen-detection-in-placenta-and-lungs-of-brucella-abortus-bovine-infected-fetuses
#18
María Andrea Fiorentino, Fernando Alberto Paolicchi, Carlos Manuel Campero, Claudio G Barbeito
Lectin binding relies on the affinity of these substances for specific terminal sugars. The method facilitates the identification of complex structures to which the terminal sugar attaches and may reveal physiological or pathological changes in cells, intracellular interactions or extracellular transport pathways. This study was carried out to investigate the effect of infection with Brucella abortus on the pattern of lectin binding in bovine fetal lungs (n=6) and bovine placentas (n=5). Fetal lungs and placenta from heifers experimentally inoculated with B...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29716804/root-cause-analysis-of-diagnostic-and-surgical-failures-in-the-treatment-of-suspected-cushing-s-disease
#19
Hasan A Zaidi, David L Penn, David J Cote, Edward R Laws
Cushing's disease (CD) is a condition characterized by excess glucocorticoid from an ACTH pituitary adenoma. Identifying surgical candidates represents a major diagnostic challenge. We performed a root cause analysis (RCA) of treatment failures for patients with suspected CD. The present study aims to categorize failures in treatment. Medical records were reviewed from 2008 to 2017 for all patients treated surgically for suspected CD. Demographics, past medical history, endocrine outcomes, imaging findings, laboratory studies and clinical features were collected...
April 28, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29704305/exponential-isothermal-amplification-of-nucleic-acids-and-amplified-assays-for-proteins-cells-and-enzyme-activities
#20
Michael S Reid, X Chris Le, Hongquan Zhang
Isothermal exponential amplification techniques, such as strand-displacement amplification (SDA), rolling circle amplification (RCA), loop-mediated isothermal amplification (LAMP), nucleic acid sequence-based amplification (NASBA), helicase-dependent amplification (HDA), and recombinase polymerase amplification (RPA), have great potential for on-site, point-of-care, and in-situ assay applications. These amplification techniques eliminate the need for temperature cycling required for polymerase chain reaction (PCR) while achieving comparable amplification yield...
April 27, 2018: Angewandte Chemie
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