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Maria Nirvana da Cruz Formiga, Marcello Ferretti Fanelli, Aldo Lourenço Abadde Dettino, Ulisses Ribaldo Nicolau, Marcelo Cavicchioli, Eduardo Nóbrega Pereira Lima, Celso Abdon Lopes de Mello
BACKGROUND: Identify in advance responder patients to chemotherapy in metastatic colorectal cancer (CRC) would allow prompt interruption of ineffective therapies in non-responder patients. Hence, predictive markers are sought in numerous trials to detect responder patients, including tumor shrinkage measured by imaging methods. Usually, Response Evaluation Criteria in Solid Tumors (RECIST) is used to evaluate tumor response in metastatic CRC, but these criteria are questionable with use of biological agents associated to chemotherapy...
June 2016: Journal of Gastrointestinal Oncology
Ashraf El Houfi, Nadeem Javed, Caitlyn T Solem, Cynthia Macahilig, Jennifer M Stephens, Nirvana Raghubir, Richard Chambers, Jim Z Li, Seema Haider
OBJECTIVES: To describe real-world treatment patterns and health care resource use and to estimate opportunities for early-switch (ES) from intravenous (IV) to oral (PO) antibiotics and early-discharge (ED) for patients hospitalized in the United Arab Emirates (UAE) with methicillin-resistant Staphylococcus aureus (MRSA) complicated skin and soft tissue infections. METHODS: This retrospective observational medical chart review study enrolled physicians from four UAE sites to collect data for 24 patients with documented MRSA complicated skin and soft tissue infections, hospitalized between July 2010 and June 2011, and discharged alive by July 2011...
2015: Infection and Drug Resistance
Nirvana Sadaghianloo, Elixène Jean-Baptiste, Hacène Gaid, Mohamed S Islam, Christophe Robino, Serge Declemy, Alan Dardik, Réda Hassen-Khodja
OBJECTIVE: The timing and urgency of salvage attempts for acutely thrombosed hemodialysis vascular accesses remain poorly defined. We examined the outcome of early surgical thrombectomy after acute access thrombosis to assess the influence of expedited timing on access salvage. METHODS: Between January 2007 and October 2012, 114 surgical thrombectomy attempts were performed on 82 patients to salvage 89 accesses. The time between the diagnosis of thrombosis and admission to the operative suite (T1), the time between diagnosis and the following dialysis session (T2), and clinical and biologic parameters were collected prospectively...
May 2014: Journal of Vascular Surgery
Aurélien Mousnier, Elixène Jean-Baptiste, Nirvana Sadaghianloo, Serge Declemy, Sophie Brizzi, Réda Hassen-Khodja
BACKGROUND: Subintimal recanalization allows for the treatment of percutaneously extended occlusive lesions. The aim of this study was to evaluate the feasibility and short- and mid-term results of subintimal recanalization in the treatment of femoropopliteal occlusive lesions in patients with critical ischemia. METHODS: Between January 2009 and December 2010, consecutive patients with critical ischemia presenting with femoropopliteal arterial occlusion were included in this study...
May 2013: Annals of Vascular Surgery
Subramani Sellappan, Casimir C Akoh
Vidalia onion varieties Nirvana, DPS 1032, Yellow 2025, King-Midas, and SBO 133 grown at Vidalia, Georgia, were analyzed for flavonoid content. A high-performance liquid chromatographic (HPLC) method with photodiode array detection was used for quantification. Compounds were analyzed as aglycons after acid hydrolysis with 1.2 M HCl. Identification of each compound was based on comparison of its retention time and UV spectra with those of pure commercial standards. Three major flavonoids, kaempferol, myricetin, and quercetin, were identified and quantified...
September 11, 2002: Journal of Agricultural and Food Chemistry
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