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https://www.readbyqxmd.com/read/29045970/-unilateral-patellar-resurfacing-in-bilateral-total-knee-arthroplasty-a-randomized-controlled-study
#1
J F Wang, Z Li, K S Zhang, F Yuan, R J Li, Q J Zhong, Z P Guan
OBJECTIVE: To perform unilateral patellar resurfacing and contralateral patellar retention in bilateral total knee arthroplasty (TKA) randomly, and to compare the clinical effects of patellar retention with patellar resurfacing in TKA. METHODS: In the study, 14 bilateral knee osteoarthritis (OA) patients were randomized in the bilateral TKA to receive unilateral patellar resurfacing and contralateral patellar retention, including 28 knees, all were females, 53 to 78 years old, with average (66...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045964/-increased-serum-c-c-chemokine-ligand-19-levels-correlated-with-b-cell-abnormalities-in-systemic-lupus-erythematosus
#2
H J Liu, L J Shi, F L Hu, H H Yao, Z G Li, Y Jia
OBJECTIVE: To detect the levels of serum C-C chemokine ligand 19 (CCL19) in patients with systemic lupus erythematosus (SLE) and to evaluate the correlation between CCL19 expression and clinical features and laboratory parameters, trying to reveal the possible role of CCL19 in the pathogenesis of systemic lupus erythematosus. METHODS: The levels of serum CCL19 were measured by enzyme linked immunosorbent assay (ELISA) in 90 patients with SLE and 30 healthy controls...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045956/-co-morbidity-of-vasovagal-syncope-and-postural-tachycardia-syndrome-with-allergic-diseases-in-children
#3
Y Liao, Q Y Zhang, H X Li, Y L Wang, P Liu, J B DU
OBJECTIVE: To explore the clinical characteristics of the co-morbidity of vasovagal syncope (VVS) and postural tachycardia syndrome (POTS) with allergic diseases in children. METHODS: A re-trospective analysis was launched to summarize the clinical data of children with VVS and POTS. They were divided into allergic group and non-allergic group according to the history of allergic diseases. The participants' clinical characteristics were compared between allergic group and non-allergic group using independent sample t test or rank sum test; composition comparisons were completed by Chi-square test...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045954/-pulmonary-arterial-hypertension-as-leading-manifestation-of-methylmalonic-aciduria-clinical-characteristics-and-gene-testing-in-15-cases
#4
X Q Liu, H Yan, J X Qiu, C Y Zhang, J G Qi, X Zhang, H J Xiao, Y L Yang, Y H Chen, J B DU
OBJECTIVE: To deepen our understanding of Methylmalonic aciduria (MMA) associated pulmonary hypertension (PH) by analyzing the characteristics of clinical presentation, pulmonary high resolusion CT(HRCT), treatment response and gene mutation. METHODS: This study includes 15 cases of pediatric patients with MMA associated PH diagnosed and treated in Peking University First Hospital pediatric department between May 2012 and May 2016 with symptoms of PH as their leading presentation...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045947/prediction-of-the-future-need-for-institutional-care-in-finnish-older-people-a-comparison-of-two-birth-cohorts
#5
Marika Salminen, Sini Eloranta, Jenni Vire, Paula Viikari, Laura Viikari, Tero Vahlberg, Aapo Lehtonen, Seija Arve, Maarit Wuorela, Matti Viitanen
BACKGROUND: More recent birth cohorts of older people have better physical and cognitive status than earlier cohorts. As such, this could be expected to diminish the need for institutional care. The prediction of the future need for institutional care provides essential information for the planning and delivery of future care and social services as well as the resources needed. OBJECTIVE: To predict the future need for institutional care among older Finnish people born in 1940...
October 19, 2017: Gerontology
https://www.readbyqxmd.com/read/29045860/mechanics-and-buckling-of-biopolymeric-shells-and-cell-nuclei
#6
Edward J Banigan, Andrew D Stephens, John F Marko
We study a Brownian dynamics simulation model of a biopolymeric shell deformed by axial forces exerted at opposing poles. The model exhibits two distinct, linear force-extension regimes, with the response to small tensions governed by linear elasticity and the response to large tensions governed by an effective spring constant that scales with radius as R(-0.25). When extended beyond the initial linear elastic regime, the shell undergoes a hysteretic, temperature-dependent buckling transition. We experimentally observe this buckling transition by stretching and imaging the lamina of isolated cell nuclei...
October 17, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/29045850/comparison-of-conventional-2d-ultrasound-to-mr-imaging-for-prenatal-estimation-of-birth-weight-in-twin-pregnancy
#7
Caroline Kadji, Elisa Bevilacqua, Ivan Hurtado, Andrew Carlin, Mieke M Cannie, Jacques C Jani
BACKGROUND: During prenatal follow-up of twin pregnancies, accurate identification of birthweight and birthweight discordance is important in order to identify the high risk group and plan perinatal care. Unfortunately prenatal evaluation of birthweight discordance by 2-dimensional ultrasound (US) has been far from optimal. OBJECTIVE: To prospectively compare estimates of fetal weight based on 2-dimensional US (US-EFW) and MR imaging (MR-EFW) to actual birth weight in women carrying twin pregnancies...
October 15, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29045707/the-social-determinants-of-lesbian-gay-bisexual-and-transgender-youth-suicidality-in-england-a-mixed-methods-study
#8
Elizabeth McDermott, Elizabeth Hughes, Victoria Rawlings
Background: Lesbian, gay, bisexual and transgender (LGBT) youth have a higher risk of suicidality and self-harm than heterosexual youth populations but little is known about the underlying mechanisms. We aimed to investigate the social determinants of this mental health inequality. Methods: A two-stage sequential mixed method study was conducted. Firstly, 29 semi-structured interviews with LGBT youth (aged 13-25 years old) were completed. Data was analysed thematically...
October 17, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/29045681/international-patterns-and-trends-in-endometrial-cancer-incidence-1978-2013
#9
Joannie Lortet-Tieulent, Jacques Ferlay, Freddie Bray, Ahmedin Jemal
Background: Cancers of the corpus uteri-primarily of the endometrium-rank as the sixth most common neoplasm in women worldwide. Analyses of the global patterns and trends of uterine cancer rates are needed in view of the ongoing obesity epidemic, a major risk factor for the disease. Methods: Data on endometrial cancer (ICD-10 C54) incidence from population-based cancer registries in 43 populations, published in CI5plus or by registries, were extracted for 1978 to 2013...
October 16, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29045671/association-between-self-rated-health-and-ideal-cardiovascular-health-the-baptist-health-south-florida-employee-study
#10
Oluseye Ogunmoroti, Ovie A Utuama, Joseph A Salami, Javier Valero-Elizondo, Erica S Spatz, Maribeth Rouseff, Don Parris, Sankalp Das, Henry Guzman, Arthur Agatston, Theodore Feldman, Emir Veledar, Wasim Maziak, Khurram Nasir
Background: There is increasing evidence of the role psychosocial factors play as determinants of cardiovascular health (CVH). We examined the association between self-rated health (SRH) and ideal CVH among employees of a large healthcare organization. Methods: Data were collected in 2014 from employees of Baptist Health South Florida during an annual voluntary health risk assessment and wellness fair. SRH was measured using a self-administered questionnaire where responses ranged from poor, fair, good, very good to excellent...
October 17, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/29045647/mechanical-aortic-valve-replacement-in-non-elderly-adults-meta-analysis-and-microsimulation
#11
Nelleke M Korteland, Jonathan R G Etnel, Bardia Arabkhani, M Mostafa Mokhles, Arezo Mohamad, Jolien W Roos-Hesselink, Ad J J C Bogers, Johanna J M Takkenberg
Aims: To support decision-making regarding prosthetic valve selection in non-elderly adults, we aim to provide a detailed overview of outcome after contemporary mechanical aortic valve replacement (AVR). Methods and results: A systematic review was conducted for papers reporting clinical outcome after AVR with bileaflet mechanical valves with a mean patient age ≥18 and ≤55 years, published between 1 January 1995 and 31 December 2015. Through meta-analysis outcomes were pooled and entered into a microsimulation model to calculate (event-free) life expectancy and lifetime event risk...
May 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29045600/development-and-validation-of-a-stability-indicating-reversed-phase-uplc-uv-method-for-the-assay-of-imidacloprid-and-estimation-of-its-related-compounds
#12
Jingzhi Tian, Abu Rustum
Imidacloprid is used as an active pharmaceutical ingredient (API) in veterinary drugs to control fleas and ticks for dogs and cats. Here we are reporting for the first time a validated stability-indicating reversed-phase UPLC-UV method for the assay of imidacloprid and estimation of its related compounds. The stability-indicating capability of this method has been demonstrated by a forced degradation study. All related compounds including processing impurities, imidacloprid API and degradates from stressed samples were well separated from each other...
October 17, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/29045595/performance-of-apanteles-hemara-hymenoptera-braconidae-on-two-amaranth-leaf-webbers-spoladea-recurvalis-and-udea-ferrugalis-lepidoptera-crambidae
#13
S T O Othim, K M Agbodzavu, R Kahuthia-Gathu, K S Akutse, S Muchemi, S Ekesi, K K M Fiaboe
Amaranth is an African indigenous vegetable that is gaining popularity due to its nutritional, medicinal, and economic values. In East Africa, frequent outbreaks of Lepidopteran leaf-webbers, Spoladea recurvalis F. (Lepidoptera: Crambidae) and Udea ferrugalis Hübner (1976) are reported on this crop, causing up to 100% foliage loss. The larval endoparasitoid Apanteles hemara Nixon is also frequently found associated with these pests during the outbreaks, however, its performance on both pests has never been documented...
October 14, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/29045567/individualized-positive-end-expiratory-pressure-in-obese-patients-during-general-anaesthesia-a-randomized-controlled-clinical-trial-using-electrical-impedance-tomography
#14
C Nestler, P Simon, D Petroff, S Hammermüller, D Kamrath, S Wolf, A Dietrich, L M Camilo, A Beda, A R Carvalho, A Giannella-Neto, A W Reske, H Wrigge
Background: General anaesthesia leads to atelectasis, reduced end-expiratory lung volume (EELV), and diminished arterial oxygenation in obese patients. We hypothesized that a combination of a recruitment manoeuvre (RM) and individualized positive end-expiratory pressure (PEEP) can avoid these effects. Methods: Patients with a BMI ≥35 kg m-2 undergoing elective laparoscopic surgery were randomly allocated to mechanical ventilation with a tidal volume of 8 ml kg-1 predicted body weight and (i) an RM followed by individualized PEEP titrated using electrical impedance tomography (PEEPIND) or (ii) no RM and PEEP of 5 cm H2O (PEEP5)...
October 16, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29045554/veliparib-with-temozolomide-or-carboplatin-paclitaxel-versus-placebo-with-carboplatin-paclitaxel-in-patients-with-brca1-2-locally-recurrent-metastatic-breast-cancer-randomized-phase-ii-study
#15
H S Han, V Diéras, M Robson, M Palácová, P K Marcom, A Jager, I Bondarenko, D Citrin, M Campone, M L Telli, S M Domchek, M Friedlander, B Kaufman, J E Garber, Y Shparyk, E Chmielowska, E H Jakobsen, V Kaklamani, W Gradishar, C K Ratajczak, C Nickner, Q Qin, J Qian, S P Shepherd, S J Isakoff, S Puhalla
Background: Homologous recombination defects in BRCA1/2-mutated tumors result in sensitivity to poly(ADP-ribose) polymerase (PARP) inhibitors, which interfere with DNA damage repair. Veliparib, a potent PARP inhibitor, enhanced the antitumor activity of platinum agents and temozolomide in early phase clinical trials. This phase II study examined the safety and efficacy of intermittent veliparib with carboplatin/paclitaxel (VCP) or temozolomide (VT) in patients with BRCA1/2-mutated breast cancer...
September 29, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29045514/exploratory-analysis-of-the-association-of-depth-of-response-and-survival-in-patients-with-metastatic-non-small-cell-lung-cancer-treated-with-a-targeted-therapy-or-immunotherapy
#16
C E McCoach, G M Blumenthal, L Zhang, A Myers, S Tang, R Sridhara, P Keegan, R Pazdur, R C Doebele, D Kazandjian
Background: Response Evaluation Criteria in Solid Tumors (RECIST) permits rapid evaluation of new therapeutic strategies in cancer. However, RECIST does not capture the heterogeneity of response in highly active therapies. Depth of tumor response may provide a more granular view of response. We explored the association between, depth of response (DepOR), with overall survival (OS) and progression free survival (PFS) for patients with NSCLC being treated with an ALK inhibitor (ALKi) or an anti-PD-1 antibody (Ab)...
August 2, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29045499/obstetric-and-psychological-characteristics-of-women-choosing-epidural-analgesia-during-labour-a-cohort-study
#17
Vasilis Sitras, Jūratė Šaltytė Benth, Malin Eberhard-Gran
OBJECTIVES: To investigate the obstetric and psychological characteristics of women who opt to use epidural analgesia (EDA) during labour and the impact of participating in labour preparation courses on women's decisions to use EDA. DESIGN: Longitudinal cohort study. SETTING: Akershus University Hospital, Norway. POPULATION: 2596 women with singleton pregnancies and intended vaginal delivery. METHODS: Data were collected using two self-completed questionnaires at pregnancy weeks 17 and 32...
2017: PloS One
https://www.readbyqxmd.com/read/29045463/submillisievert-standard-pitch-ct-pulmonary-angiography-with-ultra-low-dose-contrast-media-administration-a-comparison-to-standard-ct-imaging
#18
Saravanabavaan Suntharalingam, Christian Mikat, Elena Stenzel, Youssef Erfanian, Axel Wetter, Thomas Schlosser, Michael Forsting, Kai Nassenstein
OBJECTIVES: To evaluate the image quality and radiation dose of submillisievert standard-pitch CT pulmonary angiography (CTPA) with ultra-low dose contrast media administration in comparison to standard CTPA. MATERIALS AND METHODS: Hundred patients (56 females, 44 males, mean age 69.6±15.4 years; median BMI: 26.6, IQR: 5.9) with suspected pulmonary embolism were examined with two different protocols (n = 50 each, group A: 80 kVp, ref. mAs 115, 25 ml of contrast medium; group B: 100 kVp, ref...
2017: PloS One
https://www.readbyqxmd.com/read/29045424/cats-and-owners-interact-more-with-each-other-after-a-longer-duration-of-separation
#19
Matilda Eriksson, Linda J Keeling, Therese Rehn
Little is known about the cat's (Felis silvestris catus) need for human contact, although it is generally believed that cats are more independent pets than e.g. dogs. In this study, we investigated the effect of time left alone at home on cat behaviour (e.g. social and distress-related) before, during and after separation from their owner. Fourteen privately owned cats (single-housed) were each subjected to two treatments: the cat was left alone in their home environment for 30 min (T0.5) and for 4 h (T4). There were no differences between treatments in the behaviour of the cat (or owner) before owner departure, nor during the first 5 min of separation...
2017: PloS One
https://www.readbyqxmd.com/read/29045343/brachial-ankle-pulse-wave-velocity-compared-with-mean-arterial-pressure-and-pulse-pressure-in-risk-stratification-in-a-chinese-population
#20
Yi-Chao Lu, Ping Lyu, Hong-Yan Zhu, Dong-Xu Xu, Sulaiman Tahir, Hai-Feng Zhang, Fang Zhou, Wen-Ming Yao, Lei Gong, Yan-Li Zhou, Rong Yang, Yan-Hui Sheng, Dong-Jie Xu, Xiang-Qing Kong, Jan A Staessen, Xin-Li Li
BACKGROUND: Brachial-ankle pulse wave velocity (baPWV) can be easily measured in an observer-independent way, but lacks robust population-based validation in terms of fatal combined with nonfatal outcomes. METHOD: To address this issue, we studied 4251 Chinese randomly recruited Gaoyou County (54.1% women; mean age, 52.1). RESULTS: In the whole study population, mean values were 102.4 mmHg for mean arterial pressure (MAP), 51.1 mmHg for pulse pressure, and 14...
October 16, 2017: Journal of Hypertension
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