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https://www.readbyqxmd.com/read/28732438/investigation-of-killer-immunoglobulin-like-receptor-kir-and-hla-genotypes-to-predict-the-occurrence-of-acute-allograft-rejection-after-kidney-transplantation
#1
Davood Jafari, Mohsen Nafar, Mir Saeed Yekaninejad, Razieh Abdolvahabi, Mahboob Lesan Pezeshki, Efat Razaghi, Ali Akbar Amirzargar
After kidney transplantation, natural killer (NK) cells play a pivotal role in triggering the immune response to the allogeneic grafts primarily by their killer-cell immunoglobulin-like receptors (KIR). This process may be one mechanism that contributes to graft rejection. In this study, we have evaluated whether acute rejection after kidney transplantation was associated with predicted NK cell alloreactivity based on KIR gene and ligand along with KIR/HLA compound genotype analysis. After kidney transplantation, natural killer (NK) cells play a pivotal role in triggering the immune response to the allogeneic grafts primarily by their killer-cell immunoglobulin-like receptors (KIR)...
June 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28732434/effects-of-intraperitoneal-injection-of-allogeneic-bone-marrow-derived-mesenchymal-stem-cells-on-bronchiolitis-obliterans-in-mice-model
#2
Sakine Işık, Nevin Uzuner, Meral Karaman, Özkan Karaman, Müge Kıray, İlknur Kozanoğlu, Hüsnü Alper Bağrıyanık, Zeynep Arıkan-Ayyıldız, Melis Kartal Yandım, Yusuf Baran
Bone marrow-derived mesenchymal stem cells (BMSCs) can ameliorate a variety of lung diseases such as asthma, lung fibrosis, and acute lung injury by its anti-inflammatory and immunmodulatory effects. In this study, we developed a mouse model of bronchiolitis obliterans (BO) and evaluated the effects of the intraperitoneal administration of BMSCs on lung histopathology and cytokine levels. 25 BALB/c mice were divided into four groups; control group (Group I), BO developed and 1x106 BMSCs-injected group (Group II), non-BO, 1x106 BMSCs-injected group (Group III), and BO developed and saline-injected group (Group IV)...
June 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28732363/meta-analysis-of-the-association-between-the-inflammatory-potential-of-diet-and-colorectal-cancer-risk
#3
Yu Fan, Xin Jin, Changfeng Man, Zhenjun Gao, Xiaoyan Wang
OBJECTIVES: The inflammatory potential of diet has been inconsistently linked to colorectal cancer (CRC) risk. This meta-analysis aimed to evaluate the association of the inflammatory potential of diet, as estimated by the dietary inflammatory index (DII) score, with CRC risk. MATERIALS AND METHODS: The PubMed and Embase databases were searched for relevant studies from inception to February 2017. All cohort and case-control studies investigating the association of the DII score with CRC risk were selected...
July 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732327/prediagnostic-serum-calcium-and-albumin-and-ovarian-cancer-a-nested-case-control-study-in-the-norwegian-janus-serum-bank-cohort
#4
Gary G Schwartz, Steinar Tretli, Linda Vos, Trude E Robsahm
BACKGROUND: Women with higher serum calcium may be more likely to be diagnosed and die of ovarian cancer. We evaluated that finding in a large, prospective cohort. METHODS: We conducted a nested case-control study using a population-based biobank from Norway. We compared 202 ovarian cancer cases and 202 controls, matched for age, date at blood draw, and county of residence, with respect to serum calcium and albumin, adjusted for anthropometric variables. We evaluated risks using the entire follow-up period as well as 2-15 years and 16-25 years ("early" and "late", respectively)...
July 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28732251/nutrient-deficiency-and-obstetrical-outcomes-in-pregnant-women-following-roux-en-y-gastric-bypass-a-retrospective-danish-cohort-study-with-a-matched-comparison-group
#5
Lianna Hede Hammeken, Ramsina Betsagoo, Ann Nygaard Jensen, Anne Nødgaard Sørensen, Charlotte Overgaard
OBJECTIVE: Roux-en-Y gastric bypass surgery and small-for-gestational-age births are known to be associated although the etiology is not fully understood. This study aimed to investigate pregnancy outcomes and maternal nutritional status among pregnant women with a history of Roux-en-Y gastric bypass using maternal anemia and gestational weight gain as indicators of micronutrient and macronutrient deficiency in pregnancy. STUDY DESIGN: The study was designed as a retrospective matched cohort study...
July 12, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28732080/age-related-decrements-in-dual-task-performance-comparison-of-different-mobility-and-cognitive-tasks-a-cross-sectional-study
#6
Paolo Riccardo Brustio, Daniele Magistro, Massimiliano Zecca, Emanuela Rabaglietti, Monica Emma Liubicich
This cross-sectional study investigated the age-related differences in dual-task performance both in mobility and cognitive tasks and the additive dual-task costs in a sample of older, middle-aged and young adults. 74 older adults (M = 72.63±5.57 years), 58 middle-aged adults (M = 46.69±4.68 years) and 63 young adults (M = 25.34±3.00 years) participated in the study. Participants performed different mobility and subtraction tasks under both single- and dual-task conditions. Linear regressions, repeated-measures and one-way analyses of covariance were used, The results showed: significant effects of the age on the dual and mobility tasks (p<0...
2017: PloS One
https://www.readbyqxmd.com/read/28732068/effects-of-liver-stage-clearance-by-primaquine-on-gametocyte-carriage-of-plasmodium-vivax-and-p-falciparum
#7
Rahel Wampfler, Natalie E Hofmann, Stephan Karl, Inoni Betuela, Benson Kinboro, Lina Lorry, Mariabeth Silkey, Leanne J Robinson, Ivo Mueller, Ingrid Felger
BACKGROUND: Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatment transmission. Randomized PQ treatment in a treatment-to-reinfection cohort in Papua New Guinean children permitted the study of Pv and Pf gametocyte carriage after radical cure and to investigate the contribution of Pv relapses. METHODS: Children received radical cure with Chloroquine, Artemether-Lumefantrine plus either PQ or placebo...
July 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28731980/running-performance-nationality-sex-and-age-in-the-10-km-half-marathon-marathon-and-the-100-km-ultramarathon-iaaf-1999-2015
#8
Pantelis T Nikolaidis, Vincent O Onywera, Beat Knechtle
Nikolaidis PT, Onywera VO, and Knechtle B. Running performance, nationality, sex, and age in the 10-km, half-marathon, marathon, and the 100-km ultramarathon IAAF 1999-2015. J Strength Cond Res 31(8): 2189-2207, 2017-The aim of this study was to examine the performance of the world's best runners in the 10-km, half-marathon, marathon, and 100-km races by age, sex, and nationality during 1999-2015, using data from the International Association of Athletics Federations (IAAF). A total of 38,895 runners (17,136 women and 21,759 men) were evaluated, with 2,594 (1,360 women and 1,234 men) in the 10-km; 11,595 (5,225 women and 6,370 men) in the half-marathon; 23,973 (10,208 women and 13,765 men) in the marathon; and 733 (343 women and 390 men) in 100-km events...
August 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28731979/global-positioning-system-analysis-of-a-high-school-football-scrimmage
#9
Benjamin H Gleason, Matthew L Sams, John T Salley, A Andrew Pustina, Michael H Stone
Gleason, BH, Sams, M, Salley, JT, Pustina, A, and Stone, MH. Global positioning system analysis of a high school football scrimmage. J Strength Cond Res 31(8): 2183-2188, 2017-The purpose of this study was to examine the physical demands of a high school American football scrimmage. Male high school football players (N = 25) participated in a spring scrimmage. Global positioning system data and game film were recorded throughout the entirety of the scrimmage to determine the total distance covered, the distance covered in different velocity bands, the number of accelerations and decelerations performed, and the work-to-rest ratio of the scrimmage...
August 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28731934/long-term-evaluation-of-specular-microscopic-changes-following-nd-yag-iridotomy-in-chronic-primary-angle-closure-glaucoma-eyes
#10
Ramanjit Sihota, Esha Agarwal, Mathew James, Meena Verma, Lalit Kumar, Tanuj Dada, Viney Gupta, Kulwant Singh Kapoor
AIM: The aim of this study was to evaluate specular microscopy of chronic primary angle-closure glaucoma (CPACG) eyes at least 1 year after Nd:YAG iridotomy, and compare them with CPACG eyes without an iridotomy and age-matched, normal eyes. PATIENTS AND METHOD: Consecutive patients of CPACG at the Glaucoma service were screened. All patients underwent slit-lamp biomicroscopy, +90 D examination, and applanation tonometry. A total of 100 eyes of 100 consecutive patients of CPACG with an Nd:YAG iridotomy performed ≥1 year before, who met all inclusion/exclusion criteria, 60 consecutive CPACG eyes without an iridotomy, and 60 age and refraction-matched control eyes were enrolled...
July 20, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28731889/stent-thrombosis-with-bioabsorbable-polymer-drug-eluting-stents-insights-from-the-food-and-drug-administration-database
#11
Abdur R Khan, Avnish Tripathi, Talha A Farid, Bilal Abaid, Deepak L Bhatt, Jon R Resar, Michael P Flaherty
BACKGROUND: SYNERGY, a bioabsorbable polymer-based, everolimus-eluting stent (BP-DES), recently received regulatory approval in the USA for use in percutaneous coronary interventions. Yet, information on the safety of BP-DES in routine clinical practice is limited. Our aim was to compare the safety of the recently approved BP-DES with current durable polymer drug-eluting stents (DP-DES) by analyzing adverse events, namely, stent thrombosis (ST), reported to the Manufacturer and User Facility Device Experience (MAUDE) database...
July 20, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28731844/outcome-by-gender-in-the-veterans-health-administration-motivating-overweight-obese-veterans-everywhere-weight-management-program
#12
Bryan C Batch, Karen Goldstein, William S Yancy, Linda L Sanders, Susanne Danus, Steven C Grambow, Hayden B Bosworth
BACKGROUND: Few evaluations of the Veterans Health Administration Motivating Overweight/Obese Veterans Everywhere (MOVE!) weight management program have assessed 6-month weight change or factors associated with weight change by gender. MATERIALS AND METHODS: Analysis of administrative data from a national sample of veterans in the VA MOVE! PROGRAM: HASH(0x317f0f0) RESULTS: A total of 62,882 participants were included, 14...
July 21, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28731807/distribution-of-citations-received-by-scientific-papers-published-in-the-imaging-literature-from-2001-to-2010-decreasing-inequality-and-polarization
#13
Soo Jeong Yoon, Dae Young Yoon, Hyung Jin Lee, Sora Baek, Kyoung Ja Lim, Young Lan Seo, Eun Joo Yun
OBJECTIVE: The objective of this study was to assess the distribution of citations received by scientific papers published in the imaging literature between 2001 and 2010. MATERIALS AND METHODS: We extracted the number of citations of all articles and reviews for 5 years after publication using the Scopus (Elsevier) citation database of imaging journals between 2001 and 2010. We quantitatively analyzed article and review citations from each journal and each year, including the number, proportion, and annual number of citations of the most- (≥ 20 citations) and least-cited (three or fewer citations) papers; ratio of most-cited to least-cited papers; 75/25 percentile citation ratio; 90/10 percentile citation ratio; Gini coefficient; and Kolkata index...
August 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28731779/arthroscopic-labral-base-repair-in-the-hip-5-year-minimum-clinical-outcomes
#14
Benjamin G Domb, Leslie C Yuen, Victor Ortiz-Declet, Jody Litrenta, Itay Perets, Austin W Chen
BACKGROUND: Arthroscopic labral base repair (LBR) in the hip is a previously described technique designed to restore the native functional anatomy of the labrum by reproducing its seal against the femoral head. LBR has been shown to have good short-term outcomes. Hypothesis/Purpose: The purpose was to evaluate clinical outcomes of an LBR cohort with a minimum 5-year follow-up. It was hypothesized that patients who underwent LBR would continue to have significant improvement from their preoperative scores and maintain scores similar to their 2-year outcomes...
July 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28731606/feasibility-of-home-based-dietetic-intervention-to-improve-the-nutritional-status-of-older-adults-post-hospital-discharge
#15
Aliza Haslinda Hamirudin, Karen Walton, Karen Charlton, Amanda Carrie, Linda Tapsell, Marianna Milosavljevic, Glen Pang, Jan Potter
AIM: To determine if a model of home-based dietetic care improves dietary intake and weight status in a specific group of older adults post-hospitalisation. METHODS: The Department of Veterans' Affairs clients aged 65 years and over were recruited from hospitals in a regional area of New South Wales, Australia (n = 32 men, n = 36 women). Nutritional status was assessed at home at baseline (within two weeks post-discharge) and three months post-discharge using a diet history, a food frequency checklist and Mini Nutritional Assessment (MNA)...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731600/spot-testing-urine-ph-a-novel-dietary-biomarker-a-randomised-cross-over-trial
#16
Benjamin H Parmenter, Gary J Slater, Lynda A Frassetto
AIM: Spot-tests of urine pH are claimed to be an accessible biomarker of net acid excretion (NAE), and as such, they may be able to determine changes in an individual's intake of acid- or base-forming foods. To test this hypothesis, we aimed to determine if spot-tests of urine pH could index NAE and relay the consumption of a fruit and vegetable (F&V) concentrate whilst determining this concentrate's capacity to modulate NAE. METHODS: In a double blind, placebo-controlled, cross-over trial, healthy adults (n = 13) were allocated by simple randomisation to receive a F&V concentrate or placebo for three days each, with diet standardised throughout...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731583/the-effectiveness-of-transcutaneous-tibial-nerve-stimulation-ttns-for-adults-with-overactive-bladder-syndrome-a-systematic-review
#17
REVIEW
Joanne Booth, Lesley Connelly, Sylvia Dickson, Fiona Duncan, Maggie Lawrence
AIMS: To evaluate effectiveness of transcutaneous tibial nerve stimulation (TTNS) for treating adults with overactive bladder (OAB) of idiopathic or neurogenic origin, using a systematic review of the literature. METHODS: Systematic searches of four databases were undertaken between 1980 and 2017. Included studies investigated effects of TTNS on OAB. Study selection, data extraction, quality appraisal was performed by two independent reviewers. Narrative analysis was undertaken where meta-analysis was not possible due to study heterogeneity...
July 21, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28731580/rewiring-the-glucose-transportation-and-central-metabolic-pathways-for-overproduction-of-n-acetylglucosamine-in-bacillus-subtilis
#18
Yang Gu, Jieying Deng, Yanfeng Liu, Jianghua Li, Hyun-Dong Shin, Guocheng Du, Jian Chen, Long Liu
N-acetylglucosamine (GlcNAc) is an important amino sugar extensively used in the healthcare field. in a previous study, we constructed the recombinant Bacillus subtilis strain BSGN6-PxylA -glmS-pP43NMK-GNA1 (BN0-GNA1) for microbial production of GlcNAc by pathway design and modular optimization. Here, we further improved the production of GlcNAc by rewiring both the glucose transportation and central metabolic pathways. First, the phosphotransferase system (PTS) was blocked by deletion of three genes, yyzE (encoding the PTS system transporter subunit iiA YyzE), ypqE (encoding the PTS system transporter subunit iiA YpqE), and ptsG (encoding the PTS system glucose-specific EiiCBA component), resulting in 47...
July 21, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28731562/relative-validity-of-a-brief-fat-and-fibre-behaviour-questionnaire-in-a-population-of-overweight-and-obese-breast-cancer-survivors-a-note-of-caution
#19
Megan E Whelan, Elisabeth A H Winkler, Elizabeth G Eakin, Marina M Reeves
AIM: Dietary intake assessment is often difficult in research contexts because of time and resource constraints and participant burden. Valid, reliable and brief assessments of dietary behaviour are needed. Additionally, examination of instrument performance in a variety of populations is needed. This study assessed relative validity and responsiveness to change of the Fat and Fibre Behaviour Questionnaire (FFBQ) in a population of breast cancer survivors compared with dietary intake measured by 24-hour recalls...
February 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731446/effect-of-apoe-genotype-on-synaptic-proteins-in-earlier-adult-life
#20
Lindsey I Sinclair, Seth Love
BACKGROUND: Possession of APOEɛ4 is a strong risk factor for late-onset Alzheimer's disease and is associated with loss of synaptic proteins in the elderly even in the absence of Alzheimer's disease. OBJECTIVE: We hypothesized that ɛ4 allele possession in non-demented adults aged under-75 would also be associated with alterations in the levels of synaptic proteins. METHODS: We measured synaptophysin, PSD95, drebrin, SNAP-25, and septin 7 by ELISA in hippocampus and superior temporal gyrus from 103 adults aged <75 without dementia...
July 17, 2017: Journal of Alzheimer's Disease: JAD
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