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https://www.readbyqxmd.com/read/28299816/serum-biochemical-profile-enzymatic-activity-and-lipid-peroxidation-in-organs-of-laying-hens-fed-diets-containing-cashew-nut-shell-liquid
#1
N M Braz, E R Freitas, M T S Trevisan, G A J do Nascimento, R P R Salles, C E B Cruz, N N P Farias, I N G da Silva, P H Watanabe
The objective of this study was to evaluate the effect of feeding laying hens diets containing cashew nut shell liquid (CNSL) as a source of anacardic acid on the blood biochemical parameters as well as the enzymatic activity and lipid peroxidation of liver and tissues of the reproductive system (ovary, magnum, and uterus). A total of 216 Hisex White commercial laying hens were distributed randomly into six treatments, with six replicates of six birds. Treatments consisted of a diet without growth promoter (GP); a diet with GP; and diets without GP, with addition of increasing levels of CNSL (0...
March 16, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28281223/effects-of-excess-dietary-fluoride-on-serum-biochemical-indices-egg-quality-and-concentrations-of-fluoride-in-soft-organs-eggs-and-serum-of-laying-hens
#2
Liping Miao, Lanlan Li, Mingxing Qi, Minyao Zhou, Nannan Zhang, Xiaoting Zou
This study was conducted to investigate the effects of excess dietary fluoride (F) on serum biochemical indices, egg quality, and concentrations of F in soft tissues, eggs, and serum of laying hens. Commercial laying hens (n = 576, 51 weeks of age) were randomly allotted to 6 treatments with 6 replicates of 16 birds. The basal diets contained fluorine inclusions at a level of 16 mg/kg, and graded sodium fluoride was added to the basal diet to achieve fluorine inclusions, respectively, at a level of 200, 400, 600, 800, and 1000 mg/kg in the experimental diets...
March 9, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28238709/occludin-expression-and-regulation-in-small-follicles-of-the-layer-and-broiler-breeder-hen
#3
C S Stephens, P A Johnson
Synchronized yolk accumulation and follicle development are essential for egg production in oviparous species. In birds, yolk is incorporated into the oocyte by an avian specific yolk receptor (LR8), and it has been suggested that occludin (OCLN), a tight junction protein, mediates transfer of yolk material to the oocyte surface. OCLN may be a key regulator of yolk accumulation and follicle growth, however, the expression and regulation of OCLN in granulosa cells during various stages of follicle development is unknown...
February 24, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28178600/whole-flaxseed-diet-alters-estrogen-metabolism-to-promote-2-methoxtestradiol-induced-apoptosis-in-hen-ovarian-cancer
#4
Anushka Dikshit, Karen Hales, Dale Buchanan Hales
The study reported here demonstrates that a flaxseed-supplemented diet causes ovarian tumors in the laying hen to undergo apoptosis, resulting in a reduction of tumor burden, reducing the frequency and severity of ovarian cancer. We have previously shown in normal ovaries that flaxseed and its components down-regulate ERalpha and alter the expression of enzymes that metabolize estrogen. In this study, we analyzed the effects of the two main components of whole flaxseed, ligan and omega 3 fatty acids on estrogen metabolism and the estrogen receptor in ovarian tumors...
April 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28161970/toxicity-of-senna-occidentalis-seeds-in-laying-hens-and-its-effects-on-egg-production
#5
André T Gotardo, Mitsue Haraguchi, Paulo C F Raspantini, Maria L Z Dagli, Silvana L Górniak
Senna occidentalis is a toxic leguminous plant found in many tropical and subtropical regions of the world and causes poisoning mainly in confined animals. The seeds are the most toxic part of the plant and may be present in animal rations. The main toxic component of the S. occidentalis seed is a dianthrone, an anthraquinone-derived compound that affects mitochondrial function. This study evaluated the effects on egg production of low-level contamination of the S. occidentalis in the laying hens' diet. Forty-eight one-day-old pullets were randomly allocated into two treatment groups: control, birds that received no experimental treatment; and external and internal tegument (ET/IT), birds that received a diet containing 0...
February 6, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/27931938/improving-the-secretory-capacity-of-chinese-hamster-ovary-cells-by-ectopic-expression-of-effector-genes-lessons-learned-and-future-directions
#6
REVIEW
Henning Gram Hansen, Nuša Pristovšek, Helene Faustrup Kildegaard, Gyun Min Lee
Chinese hamster ovary (CHO) cells are the preferred cell factory for the production of therapeutic glycoproteins. Although efforts primarily within bioprocess optimization have led to increased product titers of recombinant proteins (r-proteins) expressed in CHO cells, post-transcriptional bottlenecks in the biosynthetic pathway of r-proteins remain to be solved. To this end, the ectopic expression of transgenes (effector genes) offers great engineering potential. However, studies on effector genes have in some cases led to inconsistent results...
December 6, 2016: Biotechnology Advances
https://www.readbyqxmd.com/read/27892879/cytokine-activation-during-embryonic-development-and-in-hen-ovary-and-vagina-during-reproductive-age-and-salmonella-infection
#7
M Anastasiadou, G Michailidis
Salmonellosis is one of the most important zoonotic diseases and is usually associated with consumption of Salmonella Enteritidis (SE) contaminated poultry meat or eggs. Contamination with SE is usually the result of infection of the digestive tract, or reproductive organs, especially the ovary and vagina. Thus, knowledge of endogenous innate immune mechanisms operating in the ovary and vagina of hen is an emerging aspect of reproductive physiology. Cytokines are key factors for triggering the immune response and inflammation in chicken to Salmonella infection...
December 2016: Research in Veterinary Science
https://www.readbyqxmd.com/read/27832956/effects-of-pcb-126-and-pcb-153-on-secretion-of-steroid-hormones-and-mrna-expression-of-steroidogenic-genes-star-hsd3b-cyp19a1-and-estrogen-receptors-er%C3%AE-er%C3%AE-in-prehierarchical-chicken-ovarian-follicles
#8
Andrzej Sechman, Marta Batoryna, Piotr A Antos, Anna Hrabia
The objective of this study was to assess the in vitro effects of dioxin-like PCB 126 and non-dioxin-like PCB 153 on basal and ovine LH (oLH)-stimulated testosterone (T) and estradiol (E2) secretion and expression of steroidogenic genes (STAR, HSD3B and CYP19A1) and estrogen receptors α (ERα) and β (ERβ) in white (WF) and yellowish (YF) prehierarchical follicles of the hen ovary. Steroid concentrations in a medium and gene expression in follicles following 6h of exposition were determined by RIA and real-time qPCR, respectively...
December 15, 2016: Toxicology Letters
https://www.readbyqxmd.com/read/27702917/colonization-of-internal-organs-by-salmonella-serovars-heidelberg-and-typhimurium-in-experimentally-infected-laying-hens-housed-in-enriched-colony-cages-at-different-stocking-densities
#9
Richard K Gast, Rupa Guraya, Deana R Jones, Jean Guard, Kenneth E Anderson, Darrin M Karcher
Contaminated eggs produced by infected commercial laying flocks are often implicated as sources of human infections with Salmonella Enteritidis, but Salmonella serovars Heidelberg and Typhimurium have also been associated with egg-transmitted illness. Contamination of the edible contents of eggs is a consequence of the colonization of reproductive tissues in systemically infected hens. In recent years, the animal welfare implications of diverse poultry housing and management systems have been vigorously debated, but the food safety significance of laying hen housing remains uncertain...
October 4, 2016: Poultry Science
https://www.readbyqxmd.com/read/27652192/laying-performance-digestibility-and-plasma-hormones-in-laying-hens-exposed-to-chronic-heat-stress-as-affected-by-betaine-vitamin-c-and-or-vitamin-e-supplementation
#10
Youssef A Attia, Abd El-Hamid E Abd El-Hamid, Ahmed A Abedalla, Marfat A Berika, Mohammed A Al-Harthi, Osman Kucuk, Kazim Sahin, Baha M Abou-Shehema
Heat stress had a negative effect on laying hens' performance, thus this research was to study the influences of betaine (Bet, 1000 mg/kg betaine), vitamin C (VC, 200 mg/kg ascorbic acid), and vitamin E (VE, 150 mg/kg α-Tocopherol acetate) and their possible combinations on egg production, digestibility of nutrients, plasma hormones and reproductive organs of dual-purpose hens exposed to chronic heat stress. Two hundred and eighty eight hens and thirty-six cocks from 32 to 48 weeks of age were divided into nine treatment groups of four replicates, each containing eight hens and one cock...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27610732/highly-pathogenic-eurasian-h5n8-avian-influenza-outbreaks-in-two-commercial-poultry-flocks-in-california
#11
Simone Stoute, Richard Chin, Beate Crossley, C Gabriel Sentíes-Cué, Arthur Bickford, Mary Pantin-Jackwood, Richard Breitmeyer, Annette Jones, Silvia Carnaccini, H L Shivaprasad
In January 2015, a highly pathogenic Eurasian lineage H5N8 avian influenza (AI) virus (AIV) was detected in a commercial meat turkey flock in Stanislaus County, CA. Approximately 3 wk later, a similar case was diagnosed in commercial brown layers from a different company located in Kings County, CA. Five 14-wk-old turkey hens were submitted to the California Animal Health and Food Safety Laboratory System (CAHFS), Turlock, and eleven 12-wk-old chickens were submitted to CAHFS, Tulare laboratory due to an acute increase in flock mortality...
September 2016: Avian Diseases
https://www.readbyqxmd.com/read/27599936/pathogenicity-of-virulent-infectious-bronchitis-virus-isolate-yn-on-hen-ovary-and-oviduct
#12
Qi Zhong, Yan-Xin Hu, Ji-Hui Jin, Ye Zhao, Jing Zhao, Guo-Zhong Zhang
Avian infectious bronchitis is an economically important poultry disease caused by avian infectious bronchitis virus (IBV). IBV isolate YN is a virulent strain, which is genetically similar to most of the prevalent strains in China. In this study, 21-day-old commercial laying hens were infected with IBV strain YN. The damaging effects of the virus on the reproductive organs were evaluated with clinical observations, gross autopsy and histopathological examinations during the 100-day monitoring period post infection...
September 25, 2016: Veterinary Microbiology
https://www.readbyqxmd.com/read/27505353/the-hippo-mst-pathway-member-sav1-plays-a-suppressive-role-in-development-of-the-prehierarchical-follicles-in-hen-ovary
#13
Zhichao Lyu, Ning Qin, Thobela Louis Tyasi, Hongyan Zhu, Dehui Liu, Shuguo Yuan, Rifu Xu
The Hippo/MST signaling pathway is a critical player in controlling cell proliferation, self-renewal, differentiation, and apoptosis of most tissues and organs in diverse species. Previous studies have shown that Salvador homolog 1 (SAV1), a scaffolding protein which functions in the signaling system is expressed in mammalian ovaries and play a vital role in governing the follicle development. But the exact biological effects of chicken SAV1 in prehierarchical follicle development remain poorly understood. In the present study, we demonstrated that the SAV1 protein is predominantly expressed in the oocytes and undifferentiated granulosa cells in the various sized prehierarchical follicles of hen ovary, and the endogenous expression level of SAV1 mRNA appears down-regulated from the primordial follicles to the largest preovulatory follicles (F2-F1) by immunohistochemistry and real-time RT-PCR, respectively...
2016: PloS One
https://www.readbyqxmd.com/read/27465898/enhancement-of-ovarian-tumor-detection-by-dr6-targeted-ultrasound-imaging-agents-in-laying-hen-model-of-spontaneous-ovarian-cancer
#14
Animesh Barua, Seby L Edassery, Sa'Rah McNeal, Janice M Bahr, Pincas Bitterman, Sanjib Basu, Sameer Sharma, Jacques S Abramowicz
OBJECTIVE: The lack of an effective early detection test leads to high case to death ratio of women with ovarian cancer (OVCA). To improve early detection, tumor-associated imaging targets need to be established and imaging agents to image these targets need to be developed. Targeted imaging agents offer potential for improvement of signal intensities from their targets. Expression of death receptor 6 (DR6) by ovarian malignant cells and tumor-associated microvessels increases during OVCA development and represents a novel target for ultrasound imaging...
October 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27418660/tissue-colonization-and-circulating-t-lymphocytes-in-laying-hens-upon-oral-challenge-with-salmonella-enterica-serovars
#15
Kannan V Balan, Elmer C Bigley, Dennis W Gaines, Uma S Babu
Evaluating the potential of Salmonella serovars for tissue colonization and egg contamination in laying hens is critical due to widespread consumption of poultry and egg-containing products. The 2009 FDA Egg Rule was implemented to target the eradication of Salmonella enterica Enteritidis (SE) from layers; however, other Salmonella serovars, such as Heidelberg (SH) and Typhimurium (ST), have also been associated with poultry-related outbreaks. We conducted this study to see if serovars other than SE could colonize in laying hens, cause egg contamination, and modulate circulating T-cell populations...
December 1, 2016: Poultry Science
https://www.readbyqxmd.com/read/27295280/characteristics-tissue-specific-expression-and-hormonal-regulation-of-expression-of-tyrosine-aminotransferase-in-the-avian-female-reproductive-tract
#16
W Lim, G Song
Tyrosine aminotransferase (TAT) catalyzes the transamination of tyrosine to p-hydroxyphenylpyruvate. Accumulation of tyrosine in the body due to a genetic mutation in the TAT gene causes tyrosomia type II in humans. The TAT gene is regarded as a model for studying steroid-inducible factors regulating a variety of biological functions of TAT. However, little is known of the effects of estrogen on the expression of the TAT gene in chickens. Therefore, in the present study, we identified expression of the avian TAT gene in various organs...
October 2016: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/27174747/autocrine-paracrine-proliferative-effect-of-ovarian-gh-and-igf-i-in-chicken-granulosa-cell-cultures
#17
S Marisela Ahumada-Solórzano, Carlos G Martínez-Moreno, Martha Carranza, José Ávila-Mendoza, José Luis Luna-Acosta, Steve Harvey, Maricela Luna, Carlos Arámburo
It is known that growth hormone (GH) and its receptor (GHR) are expressed in granulosa cells (GC) and thecal cells during the follicular development in the hen ovary, which suggests GH is involved in autocrine/paracrine actions in the female reproductive system. In this work, we show that the knockdown of local ovarian GH with a specific cGH siRNA in GC cultures significantly decreased both cGH mRNA expression and GH secretion to the media, and also reduced their proliferative rate. Thus, we analyzed the effect of ovarian GH and recombinant chicken GH (rcGH) on the proliferation of pre-hierarchical GCs in primary cultures...
August 1, 2016: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/27143766/comparative-evaluation-of-dietary-supplementation-with-mannan-oligosaccharide-and-oregano-essential-oil-in-forced-molted-and-fully-fed-laying-hens-between-82-and-106-weeks-of-age
#18
M Bozkurt, E Bintaş, Ş Kırkan, H Akşit, K Küçükyılmaz, G Erbaş, M Çabuk, D Akşit, U Parın, G Ege, B Koçer, K Seyrek, A E Tüzün
The aim of this study was to investigate the efficacy of feed-grade preparations of mannan oligosaccharides ( MOS: ) and oregano essential oil ( OEO: ) in forced molted or fully fed 82-week-old, laying hens. A 2 × 3 factorial experiment investigated the influence of molting vs. full feeding and dietary supplements [i.e., unsupplemented control, MOS (1 g/kg) diet, and OEO (24 mg/kg) diet] on production parameters, egg quality, serum stress indicators, blood constituents, tibial characteristics, liver antioxidant status, and cecal microflora composition...
November 1, 2016: Poultry Science
https://www.readbyqxmd.com/read/27118516/alteration-of-gene-expression-by-zinc-oxide-nanoparticles-or%C3%A2-zinc-sulfate-in%C3%A2-vivo-and-comparison-with-in%C3%A2-vitro-data-a%C3%A2-harmonious-case
#19
Wei-Dong Zhang, Yong Zhao, Hong-Fu Zhang, Shu-Kun Wang, Zhi-Hui Hao, Jing Liu, Yu-Qing Yuan, Peng-Fei Zhang, Hong-Di Yang, Wei Shen, Lan Li
Granulosa cells (GCs) are those somatic cells closest to the female germ cell. GCs play a vital role in oocyte growth and development, and the oocyte is necessary for multiplication of a species. Zinc oxide (ZnO) nanoparticles (NPs) readily cross biologic barriers to be absorbed into biologic systems that make them promising candidates as food additives. The objective of the present investigation was to explore the impact of intact NPs on gene expression and the functional classification of altered genes in hen GCs in vivo, to compare the data from in vivo and in vitro studies, and finally to point out the adverse effects of ZnO NPs on the reproductive system...
August 2016: Theriogenology
https://www.readbyqxmd.com/read/27025442/the-effect-of-cooling-management-on-blood-flow-to-the-dominant-follicle-and-estrous-cycle-length-at-heat-stress
#20
Hen Honig, Lior Ofer, Moshe Kaim, Shamay Jacobi, Dima Shinder, Eran Gershon
The use of ultrasound imaging for the examination of reproductive organs has contributed substantially to the fertility management of dairy cows around the world. This method has many advantages such as noninvasiveness and immediate availability of information. Adding Doppler index to the ultrasound imaging examination, improved the estimation of blood volume and flow rate to the ovaries in general and to the dominant follicle in particular. The aim of this study was to examine changes in the blood flow to the dominant follicle and compare them to the follicular development throughout the cycle...
July 15, 2016: Theriogenology
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