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https://www.readbyqxmd.com/read/28807533/evaluation-of-the-effects-of-prostate-radiation-therapy-on-occludin-expression-and-ultrasonography-characteristics-of-the-bladder
#1
Milad Baradaran-Ghahfarokhi, Alireza Amouheidari, Daryoush Shahbazi-Gahrouei, Hamid Reza Baradaran-Ghahfarokhi, Kari Tanderup, Wolfgang Dörr, Parvaneh Shokrani
PURPOSE: To evaluate the effects of radiation dose in prostate radiation therapy (RT) on occludin expression and ultrasonography characteristics of the bladder. METHODS AND MATERIALS: Urine samples of 64 prostate RT patients were collected before, at regular intervals during, and 3 months after RT. Occludin expression analysis was performed, and bladder wall echogenicity and echotexture were investigated by ultrasound and the gray-scale histogram analysis method...
June 20, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28779902/-erythropoiesis-stimulating-agents-literature-review-of-uses-and-indications-in-advanced-oncological-and-non-oncological-disease-in-the-elderly
#2
Nieves Fernandez Letamendi, Teresa Fernandez Letamendi, M Angeles Montañes Gracia, Valle Recasens Flores
The aim of this article is to review possible indications and controversies about the most frequent uses of ESAs in the treatment of anaemia in elderly patients with oncological and non-oncological diseases. Using PubMed a systematic review was carried out on articles published from 1985 to September 2016, as well as a review of the main Spanish, European, and American consensus guidelines on each of the following diseases in which could pose the treatment of anaemia associated with ESA. A review was also carried out on the main Spanish, European and American consensus guidelines regarding the management of anaemia related to the diseases outlined in this article...
August 2, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28618234/successful-treatment-of-acute-radiation-proctitis-with-aloe-vera-a-preliminary-randomized-controlled-clinical-trial
#3
Adeleh Sahebnasagh, Arash Ghasemi, Jafar Akbari, Abbas Alipour, Hossein Lashkardoost, Shahram Ala, Ebrahim Salehifar
BACKGROUND: Acute radiation proctitis (ARP) is a common side-effect that affects up to 50% of patients receiving radiotherapy. The aim of this study was to evaluate the role of a topical preparation of Aloe vera in the treatment of ARP induced by radiotherapy of pelvic area. SUBJECTS AND INTERVENTIONS: In this double-blind placebo-controlled trial, 20 consecutive patients with ARP after external-beam radiation therapy (46-72 Gy) of pelvic malignancies were randomized to receive either Aloe vera 3% or placebo ointment, 1 g twice daily for 4 weeks...
June 15, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28549594/-recommendations-for-the-organ-donation-from-patients-with-brain-or-medullary-primitive-tumors-on-behalf-of-the-association-of-the-neuro-oncologists-of-french-expression-anocef-and-the-club-of-neuro-oncology-of-the-french-society-of-neurosurgery
#4
REVIEW
Didier Frappaz, Emilie Le Rhun, Arnaud Dagain, Benoît Averland, Luc Bauchet, Alexandre Faure, Christian Guillaume, Sonia Zouaoui, François Provot, Florence Vachiery, Luc Taillandier, Khê Hoang-Xuan
Requests of organs to be transplanted increase. As a matter of urgency, it is not always easy to decide if a patient carrier of a brain tumor can be candidate in the donation. After a review of the literature, the members of the Association of the Neuro-oncologists of French Expression (ANOCEF) and the Club of Neuro-oncology of the French Society of Neurosurgery propose consensual recommendations in case of donor carrier of primitive tumor intra-cranial or intra-medullary. A contact with the neuro-oncologist/neurosurgeon will allow to discuss the indication in case of glioma of grade I/II/III, according to the grade, the current status (absence of progressive disease), the number of surgeries and of lines of treatment...
May 23, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28490359/cryopreservation-of-reproductive-material-before-cancer-treatment-a-qualitative-study-of-health-care-professionals-views-about-ways-to-enhance-clinical-care
#5
Karin Hammarberg, Maggie Kirkman, Catharyn Stern, Robert I McLachlan, Debra Gook, Luk Rombauts, Beverley Vollenhoven, Jane R W Fisher
BACKGROUND: Cancer treatment can diminish fertility in women and men. The need for fertility preservation is growing as increasing numbers of people survive cancer. Cryostorage of reproductive material to preserve potential for conception for cancer survivors has moved from being experimental to being a part of clinical management of women and men who are diagnosed with cancer in their reproductive years. There is little existing evidence about how fertility preservation services can be enhanced to meet the complex needs of patients who are diagnosed with cancer in their reproductive years...
May 10, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28247630/-salvage-external-beam-radiation-therapy-for-prostate-cancer-recurrence-after-high-intensity-focused-ultrasound-ablation
#6
R N Fomkin, V M Popkov, T V Shatylko
The article outlines oncological and functional outcomes of salvage external beam radiation therapy after HIFU-ablation in 49 patients. The study determined overall and relapse-free survival, compared the rates of adverse events stratified by CTCAE, erectile function and continence scores assessed by questionnaire survey. Univariate and multivariate analysis of risk factors for failure of salvage radiation therapy after prostate HIFU-ablation were conducted. In univariate analysis the level of prostate-specific antigen (PSA) prior to radiotherapy, the risk group, PSA nadir after radiotherapy, PSA nadir greater than 0...
August 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28186840/fertility-preservation-care-for-children-and-adolescents-with-cancer-an-inquiry-to-quantify-professionals-barriers
#7
Nikoletta Panagiotopoulou, Frederik W van Delft, Juliet P Hale, Jane A Stewart
PURPOSE: There is a growing interest in fertility preservation as emerging research is highlighting the prevalence of infertility among young cancer survivors and its negative impact on quality of life. Previous qualitative research has identified barriers of fertility preservation care among professionals. The aim of this study was to assess the prevalence of these barriers among pediatric and adolescent oncology healthcare professionals and evaluate factors that influence them. METHODS: Based on previously identified barriers and experts' input, a questionnaire was developed and sent to 88 professionals drawn from the multidisciplinary pediatric and adolescent oncology team of a large Principal Treatment Centre...
February 10, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28152724/utilization-of-an-innovative-tool-to-improve-oncology-patient-outcomes
#8
Jessica O'Driscoll, Jaimika Patel, Marie Decker, Joanne McGovern
231 Background: Introduction of an electronic board can improve interdisciplinary communication to ensure early intervention and improve patient outcomes. Early detection and prevention is key. The early stages of physiologic demise may be demonstrated by subtle changes in the patient's vital signs. The purpose of this study was to implement a visual tool to indicate and update the acuity of patients on the oncology unit. The parameters displayed included vital signs, Hendrich, and Braden scale. The goal of the electronic board was to create a continuously accessible resource for the interdisciplinary team for rapid assessment of the patient's condition throughout rounds and all shifts...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28118213/a-case-report-subanesthetic-ketamine-infusion-for-treatment-of-cancer-related-pain-produces-urinary-urge-incontinence
#9
Barbara A Vickers, Wayne Lee, Joann Hunsberger
Oncology patients undergoing treatment can experience substantial pain related to their disease or prescribed therapy. Ketamine infusions at subanesthetic doses have been used at our institution to supplement the pain management regimens of 262 patients. We present 2 cases in which young adult patients being treated with subanesthetic ketamine for cancer-related pain experienced urinary urgency and incontinence after initiation or increase of the ketamine infusion. This adverse effect has not been reported previously at this dosing range...
January 23, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28068157/cancer-survivors-preference-for-follow-up-care-providers-a-cross-sectional-study-from-the-population-based-profiles-registry
#10
Lotte J Huibertse, Mies van Eenbergen, Belle H de Rooij, Maarten T Bastiaens, Laurent M C L Fossion, Rob B de la Fuente, Paul J M Kil, Evert L Koldewijn, A H P Meier, Roland J M Mommers, A Q Niemer, Jorg R Oddens, Eric H G M Oomens, Mandy Prins, Kees-Peter de Roos, Monique R T M Thissen, Martine W H Timmermans, Bart P Wijsman, Lonneke V van de Poll-Franse, Nicole P M Ezendam
BACKGROUND: The best practice for the organization of follow-up care in oncology is under debate, due to growing numbers of cancer survivors. Understanding survivors' preferences for follow-up care is elementary for designing patient-centred care. Based on data from prostate cancer and melanoma survivors, this study aims to identify: 1) preferences for follow-up care providers, for instance the medical specialist, the oncology nurse or the general practitioner; 2) characteristics associated with these preferences and 3) the preferred care provider to discuss cancer-related problems...
February 2017: Acta Oncologica
https://www.readbyqxmd.com/read/27822086/danish-colorectal-cancer-group-database
#11
REVIEW
Peter Ingeholm, Ismail Gögenur, Lene H Iversen
AIM OF DATABASE: The aim of the database, which has existed for registration of all patients with colorectal cancer in Denmark since 2001, is to improve the prognosis for this patient group. STUDY POPULATION: All Danish patients with newly diagnosed colorectal cancer who are either diagnosed or treated in a surgical department of a public Danish hospital. MAIN VARIABLES: The database comprises an array of surgical, radiological, oncological, and pathological variables...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27734798/rectal-bleeding-and-prolapse%C3%A2-not-always-benign-diseases-rather-anal-cancer-the-importance-of-a-correct-decision-making-since-primary-care
#12
G Cocorullo, R Tutino, N Falco, T Fontana, G Salamone, L Licari, G Gulotta
Rectal bleeding is very common in general population with a prevalence of 10-20 %. Primary care physicians have to stratify patients basing on urgency and on the colo-rectal cancer risk and to conduct a decision making for the correct management. We report a case of a 61-years-old woman, complaining rectal bleeding and an anal mass attended to their family doctor who does a visit but without a digital rectal examination and diagnosed a hemorrhoidal prolapse suggesting medical therapy. For the persistence of symptoms she comes to our service from emergency attention...
May 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27600298/profiling-clinical-platelet-and-plasma-use-to-inform-blood-supply-and-contingency-planning-puppy-the-prospective-utilization-of-platelets-and-plasma-study
#13
Pasquale L Fedele, Mark N Polizzotto, George Grigoriadis, Neil Waters, Mary Comande, Marija Borosak, David Portbury, Erica M Wood
BACKGROUND: Demand for platelet (PLT) and plasma transfusions is increasing. Improved clinical supply and contingency planning requires greater understanding of usage profiles and urgency of clinical requirement. STUDY DESIGN AND METHODS: This study was a random-sample survey of PLT and plasma units produced in Victoria, Australia, to determine product disposition, recipient demographics, clinical indications for transfusion, and urgency (or "deferability") of need...
October 2016: Transfusion
https://www.readbyqxmd.com/read/27529573/a-review-of-the-oncology-patient-s-challenges-for-utilizing-fertility-preservation-services
#14
Dina M Flink, Jeanelle Sheeder, Laxmi A Kondapalli
PURPOSE: The American Society of Clinical Oncology issued practice guidelines in 2006 to provide critical information about fertility impact to adolescents and young adults (AYA) at the time of cancer diagnosis. Survivors continue to express concerns about their long-term reproductive health after cancer therapy even as treatment options for fertility preservation evolve. An underutilization of fertility preservation methods by cancer patients continues to persist. A review of the literature cites barriers and challenges that limit fertility information and preservation options for AYA cancer patients...
March 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/27505051/core-outcomes-for-colorectal-cancer-surgery-a-consensus-study
#15
Angus G K McNair, Robert N Whistance, Rachael O Forsythe, Rhiannon Macefield, Jonathan Rees, Anne M Pullyblank, Kerry N L Avery, Sara T Brookes, Michael G Thomas, Paul A Sylvester, Ann Russell, Alfred Oliver, Dion Morton, Robin Kennedy, David G Jayne, Richard Huxtable, Roland Hackett, Susan J Dutton, Mark G Coleman, Mia Card, Julia Brown, Jane M Blazeby
BACKGROUND: Colorectal cancer (CRC) is a major cause of worldwide morbidity and mortality. Surgical treatment is common, and there is a great need to improve the delivery of such care. The gold standard for evaluating surgery is within well-designed randomized controlled trials (RCTs); however, the impact of RCTs is diminished by a lack of coordinated outcome measurement and reporting. A solution to these issues is to develop an agreed standard "core" set of outcomes to be measured in all trials to facilitate cross-study comparisons, meta-analysis, and minimize outcome reporting bias...
August 2016: PLoS Medicine
https://www.readbyqxmd.com/read/26991701/2016-creating-a-culture-of-safety-in-oncology
#16
Lisa Kennedy Sheldon
Nurses play vital roles in preventing errors and improving the quality of care for patients. However, in the breakthrough Institute of Medicine (IOM) reports, To Err Is Human: Building a Safer Health System (IOM, 1999) and Crossing the Quality Chasm: A New Health System for the 21st Century (IOM, 2001), it was estimated that about 44,000-98,000 Americans die each year as a result of medical errors. Gibson and Singh's (2003) book, Wall of Silence: The Untold Story of the Medical Mistakes That Kill and Injure Millions of Americans, shared real-life stories of medical mistakes to help raise awareness and create a sense of urgency for the issues surrounding healthcare errors...
April 2016: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/26341520/patients-experiences-and-perspectives-of-multiple-concurrent-symptoms-in-advanced-cancer-a-semi-structured-interview-study
#17
Skye T Dong, Phyllis N Butow, Allison Tong, Meera Agar, Frances Boyle, Benjamin C Forster, Martin Stockler, Melanie R Lovell
PURPOSE: Patients with advanced cancer typically experience multiple concurrent symptoms, which have a detrimental impact on patient outcomes. No studies to date have qualitatively explored advanced cancer patients' perceptions of multiple symptoms in oncology and palliative care settings. Understanding the experience of multiple symptoms can inform integrated clinical pathways for treating, assessing and reducing symptom burden. This study aims to describe the beliefs, attitudes and experiences of patients with multiple symptoms in advanced cancer...
March 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/26264590/long-term-effects-of-neoadjuvant-chemoradiotherapy-followed-by-sphincter-preserving-resection-on-anal-sphincter-function-in-relation-to-quality-of-life-among-locally-advanced-rectal-cancer-patients-a-cross-sectional-analysis
#18
Zerrin Ozgen, Sevgi Ozden, Beste M Atasoy, Hazan Ozyurt, Rasim Gencosmanoglu, Nese Imeryuz
BACKGROUND: There is growing recognition for the consequences of rectal cancer treatment to maintain an adequate functional sphincter in the long-term rather than preserving the anal sphincter itself. This study aims to evaluate long-term effects of neoadjuvant chemoradiotherapy (nCRT) followed by sphincter-preserving resection on anal sphincter function in relation to quality of life (QoL) among locally advanced rectal cancer patients. METHODS: Twenty-nine patients treated with nCRT followed by low anterior resection surgery were included in this study...
2015: Radiation Oncology
https://www.readbyqxmd.com/read/26126000/self-reported-health-related-quality-of-life-issues-for-aboriginal-and-torres-strait-islander-patients-with-experience-of-cancer-in-australia-a-review-of-literature
#19
REVIEW
Jasmine M Micklem
BACKGROUND: Aboriginal peoples and Torres Strait Islander peoples (who comprise the indigenous people or the original inhabitants of Australia before colonization) are more likely to experience cancers with poorer prognoses, are more likely to be diagnosed with cancer at a later stage of disease progression, are less likely to receive adequate cancer treatment and are more likely to pass away due to cancer, compared with other Australians. Cancer and biomedical therapies for cancer often have significant, ongoing effects on patient health-related quality of life (HRQL)...
December 2015: International Journal of Evidence-based Healthcare
https://www.readbyqxmd.com/read/26068490/systematic-review-of-radiation-therapy-toxicity-reporting-in-randomized-controlled-trials-of-rectal-cancer-a-comparison-of-patient-reported-outcomes-and-clinician-toxicity-reporting
#20
REVIEW
Alexandra Gilbert, Lucy Ziegler, Maisie Martland, Susan Davidson, Fabio Efficace, David Sebag-Montefiore, Galina Velikova
The use of multimodal treatments for rectal cancer has improved cancer-related outcomes but makes monitoring toxicity challenging. Optimizing future radiation therapy regimens requires collection and publication of detailed toxicity data. This review evaluated the quality of toxicity information provided in randomized controlled trials (RCTs) of radiation therapy in rectal cancer and focused on the difference between clinician-reported and patient-reported toxicity. Medline, EMBASE, and the Cochrane Library were searched (January 1995-July 2013) for RCTs reporting late toxicity in patients treated with regimens including preoperative (chemo)radiation therapy...
July 1, 2015: International Journal of Radiation Oncology, Biology, Physics
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