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https://www.readbyqxmd.com/read/28749331/pertussis-surveillance-and-control-exploring-variations-and-delays-in-testing-laboratory-diagnostics-and-public-health-service-notifications-the-netherlands-2010-to-2013
#1
Jeanne Heil, Henriëtte L G Ter Waarbeek, Christian J P A Hoebe, Peter H A Jacobs, Dirk W van Dam, Thera A M Trienekens, Jochen W L Cals, Inge H M van Loo, Nicole H T M Dukers-Muijrers
Pertussis is most severe among unvaccinated infants (< 1 year of age), and still leads to several reported deaths in the Netherlands every year. In order to avoid pertussis-related infant morbidity and mortality, pertussis surveillance data are used to guide pertussis control measures. However, more insight into the accuracy of pertussis surveillance and control, and into the range of healthcare and public health-related factors that impede this are needed. We analysed a unique combination of data sources from one Dutch region of 1...
July 13, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28744699/evaluating-iowa-severe-maternal-morbidity-trends-and-maternal-risk-factors-2009-2014
#2
Brittni N Frederiksen, Catherine J Lillehoj, Debra J Kane, Dave Goodman, Kristin Rankin
Objectives To describe statewide SMM trends in Iowa from 2009 to 2014 and identify maternal characteristics associated with SMM, overall and by age group. Methods We used 2009-2014 linked Iowa birth certificate and hospital discharge data to calculate SMM based on a 25-condition definition and 24-condition definition. The 24-condition definition parallels the 25-condition definition, but excludes blood transfusions. We calculated SMM rates for all delivery hospitalizations (N = 196,788) using ICD-9-CM diagnosis and procedure codes...
July 25, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28735811/improving-hospital-quality-to-reduce-disparities-in-severe-maternal-morbidity-and-mortality
#3
Elizabeth A Howell, Jennifer Zeitlin
Significant racial/ethnic disparities in maternal morbidity and mortality exist in the United States. Black women are 3-4 times more likely to die a pregnancy-related death as compared with white women. Growing research suggests that hospital quality may be a critical lever for improving outcomes and narrowing disparities. This overview reviews the evidence demonstrating that hospital quality is related to maternal mortality and morbidity, discusses the pathways through which these associations between quality and severe maternal morbidity generate disparities, and concludes with a discussion of possible levers for action to reduce disparities by improving hospital quality...
July 20, 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/28734972/non-tubal-ectopic-pregnancies-an-overview-and-treatment-via-local-injection
#4
REVIEW
A V Dolinko, R A Vrees, G N Frishman
Ectopic pregnancies account for 1.5-2% of all pregnancy in the United States. Of these, approximately 10 percent implant in non-tubal locations, including the abdominal cavity, cervix, ovary, interstitial portion of the fallopian tube, broad ligament, the uterine cornua, or within a cesarean section scar. Because these pregnancies tend to present later than typical tubal pregnancies, they have been associated with greater maternal morbidity and mortality. Advances in ultrasound technology have allowed for earlier diagnosis of non-tubal ectopic pregnancies, which in turn has led to the development of novel minimally invasive techniques to manage them...
July 19, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28733065/severe-maternal-morbidity-associated-with-maternal-birthplace-a-population-based-register-study
#5
Marcelo L Urquia, Susitha Wanigaratne, Joel G Ray, K S Joseph
OBJECTIVE: This study sought to quantify the risk of severe maternal morbidity (SMM) according to maternal country of birth in Canada. METHODS: The study analyzed 1 252 543 in-hospital deliveries of Ontario residents discharged between April 1, 2002, and March 31, 2012. The main outcome measure was a composite indicator of SMM used for surveillance. The top 10 most common component conditions were also evaluated. Maternal country of birth and other immigration characteristics were obtained through linkage with official immigration records...
July 18, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28731823/maternal-fetal-outcomes-in-34-pregnant-women-with-type-1-diabetes-in-sensor-augmented-insulin-pump-therapy
#6
Ana María Gómez, Lisseth Fernanda Marín Carrillo, Carol M Arévalo Correa, Oscar Mauricio Muñoz Velandia, Martín Alonso Rondón Sepúlveda, Jaime Luis Silva Herrera, Diana Cristina Henao Carrillo
BACKGROUND: Pregnancy in women with type 1 diabetes (T1D) is associated with increased risk of maternal complications and neonatal morbidity and mortality. Optimizing glycemic control improves these outcomes. OBJECTIVE: To describe the experience of using sensor-augmented insulin pump therapy (SAPT) and SAPT + low-glucose suspension (LGS) on pregnant women with T1D, including neonatal and maternal outcomes. METHODS: A prospective observational study was conducted in women with T1D who started SAPT and SAPT + LGS before or during pregnancy at the San Ignacio University Hospital Diabetes Center in Bogotá, Colombia...
July 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28729012/evidence-that-children-born-at-early-term-37-38-6-7-weeks-are-at-increased-risk-for-diabetes-and-obesity-related-disorders
#7
Dorit Paz Levy, Eyal Sheiner, Tamar Wainstock, Ruslan Sergienko, Daniella Landau, Asnat Walfisch
BACKGROUND: Prematurity is known to be associated with high rates of endocrine and metabolic complications in the offspring. Early term (37 0/7-38 6/7 weeks' gestation) born offspring were also shown to exhibit long term morbidity resembling that of late preterm, in several health categories. OBJECTIVE: We aimed to determine whether early term delivery impacts on the long-term endocrine and metabolic health of the offspring. STUDY DESIGN: A population-based cohort analysis was performed, including all term singleton deliveries occurring during 1991-2013 at a single regional tertiary medical center...
July 17, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28726984/physiology-and-endocrinology-symposium-alterations-in-uteroplacental-hemodynamics-during-melatonin-supplementation-in-sheep-and-cattle
#8
C O Lemley, K A Vonnahme
Compromised placental function can result in fetal growth restriction which is associated with greater risk of neonatal morbidity and mortality. Large increases in transplacental nutrient and waste exchange, which support the exponential increase in fetal growth during the last half of gestation, are dependent primarily on the rapid growth and vascularization of the uteroplacenta. The amplitude of melatonin secretion has been associated with improved oxidative status and altered cardiovascular function in several mammalian species; however, melatonin mediated alterations of uteroplacental capacity in sheep and cattle are lacking...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28722551/promoting-research-to-improve-maternal-neonatal-infant-and-adolescent-health-in-west-africa-the-role-of-the-west-african-health-organisation
#9
Issiaka Sombie, Aissa Bouwayé, Yves Mongbo, Namoudou Keita, Virgil Lokossou, Ermel Johnson, Laurent Assogba, Xavier Crespin
West Africa has adopted numerous strategies to counter maternal and infant mortality, provides national maternal and infant health programmes, and hosts many active technical and financial partners and non-governmental organisations. Despite this, maternal and infant morbidity and mortality indicators are still very high. In this commentary, internal actors and officials of the West African Health Organisation (WAHO) examine the regional organisation's role in promoting research as a tool for strengthening maternal and infant health in West Africa...
July 12, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28720616/concomitant-preterm-birth-and-severe-small-for-gestational-age-birth-weight-among-infants-of-immigrant-mothers-in-ontario-originating-from-the-philippines-and-east-asia-a-population-based-study
#10
Emily Bartsch, Alison L Park, Jennifer Jairam, Joel G Ray
OBJECTIVES: Women from the Philippines form one of the largest immigrant groups to North America. Their newborns experience higher rates of preterm birth (PTB), and separately, small-for-gestational age (SGA) birth weight, compared with other East Asians. It is not known if Filipino women are at elevated risk of concomitant PTB and severe SGA (PTB-SGA), a pathological state likely reflective of placental dysfunction and neonatal morbidity. METHODS: We conducted a population-based study of all singleton or twin live births in Ontario, from 2002 to 2011, among immigrant mothers from the Philippines (n=27 946), Vietnam (n=15 297), Hong Kong (n=5618), South Korea (n=5148) and China (n=42 517)...
July 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28713331/thyroid-stimulating-hormone-receptor-antibodies-in-pregnancy-clinical-relevance
#11
REVIEW
Ines Bucci, Cesidio Giuliani, Giorgio Napolitano
Graves' disease is the most common cause of thyrotoxicosis in women of childbearing age. Approximately 1% of pregnant women been treated before, or are being treated during pregnancy for Graves' hyperthyroidism. In pregnancy, as in not pregnant state, thyroid-stimulating hormone (TSH) receptor (TSHR) antibodies (TRAbs) are the pathogenetic hallmark of Graves' disease. TRAbs are heterogeneous for molecular and functional properties and are subdivided into activating (TSAbs), blocking (TBAbs), or neutral (N-TRAbs) depending on their effect on TSHR...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28711079/new-evidence-in-the-management-of-chronic-hypertension-in-pregnancy
#12
Tiina Podymow, Phyllis August
Chronic hypertension complicates 1% to 5% of all pregnancies, but debate continues regarding the benefits of lowering blood pressure in pregnancy as well as the optimal blood pressure targets. Women with chronic hypertension are at significant risk for maternal and fetal morbidity and mortality, yet it remains unclear whether antihypertensive treatment during pregnancy lowers these risks. Severe hypertension (systolic ≥ 160 mm Hg) should be treated, but there is considerable variability in the approach to mild-to-moderate hypertension (140-159/90-109 mm Hg)...
July 2017: Seminars in Nephrology
https://www.readbyqxmd.com/read/28710882/mid-trimester-preterm-premature-rupture-of-membranes-pprom-etiology-diagnosis-classification-international-recommendations-of-treatment-options-and-outcome
#13
REVIEW
Michael Tchirikov, Natalia Schlabritz-Loutsevitch, James Maher, Jörg Buchmann, Yuri Naberezhnev, Andreas S Winarno, Gregor Seliger
Mid-trimester preterm premature rupture of membranes (PPROM), defined as rupture of fetal membranes prior to 28 weeks of gestation, complicates approximately 0.4%-0.7% of all pregnancies. This condition is associated with a very high neonatal mortality rate as well as an increased risk of long- and short-term severe neonatal morbidity. The causes of the mid-trimester PPROM are multifactorial. Altered membrane morphology including marked swelling and disruption of the collagen network which is seen with PPROM can be triggered by bacterial products or/and pro-inflammatory cytokines...
July 15, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28709727/consensus-bundle-on-severe-hypertension-during-pregnancy-and-the-postpartum-period
#14
Peter S Bernstein, James N Martin, John R Barton, Laurence E Shields, Maurice L Druzin, Barbara M Scavone, Jennifer Frost, Christine H Morton, Catherine Ruhl, Joan Slager, Eleni Z Tsigas, Sara Jaffer, M Kathryn Menard
Complications arising from hypertensive disorders of pregnancy are among the leading causes of preventable severe maternal morbidity and mortality. Timely and appropriate treatment has the potential to significantly reduce hypertension-related complications. To assist health care providers in achieving this goal, this patient safety bundle provides guidance to coordinate and standardize the care provided to women with severe hypertension during pregnancy and the postpartum period. This is one of several patient safety bundles developed by multidisciplinary work groups of the National Partnership for Maternal Safety under the guidance of the Council on Patient Safety in Women's Health Care...
July 1, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28709445/twin-twin-transfusion-syndrome-study-protocol-for-developing-disseminating-and-implementing-a-core-outcome-set
#15
Asma Khalil, Helen Perry, James Duffy, Keith Reed, Ahmet Baschat, Jan Deprest, Kurt Hecher, Liesbeth Lewi, Enrico Lopriore, Dick Oepkes
BACKGROUND: Twin-Twin Transfusion Syndrome (TTTS) is associated with an increased risk of perinatal mortality and morbidity. Several treatment interventions have been described for TTTS, including fetoscopic laser surgery, amnioreduction, septostomy, expectant management, and pregnancy termination. Over the last decade, fetoscopic laser surgery has become the primary treatment. The literature to date reports on many different outcomes, making it difficult to compare results or combine data from individual studies, limiting the value of research to guide clinical practice...
July 14, 2017: Trials
https://www.readbyqxmd.com/read/28707745/survival-of-the-fetus-during-maternal-thoracotomy-under-cardiopulmonary-bypass-for-infective-endocarditis
#16
Li Luo, Qiulei Sun, Liping Chen, Demei Ying, Xiaohua Wu, Zhengqiong Chen
Infective endocarditis (IE) during pregnancy is a rare but serious condition. Cardiopulmonary bypass during pregnancy has a high rate of fetal morbidity and mortality. We here report the case of a 22-year-old pregnant woman with confirmed IE. Multiple large cardiac valve vegetations, severe aortic valve regurgitation, and hemodynamic compromise were observed. With full implementation of fetal monitoring and protection strategies, open heart surgery was performed at 31.4 weeks' gestation to aid survival, followed by an elective cesarean delivery at 34...
July 14, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28701023/preterm-preeclampsia-and-timing-of-delivery-a-systematic-literature-review
#17
José Paulo de Siqueira Guida, Fernanda Garanhani Surita, Mary Angela Parpinelli, Maria Laura Costa
Introduction Preeclampsia, a multifactorial disease with pathophysiology not yet fully understood, is a major cause of maternal and perinatal morbidity and mortality, especially when preterm. The diagnosis is performed when there is an association between arterial hypertension and proteinuria or evidence of severity. There are unanswered questions in the literature considering the timing of delivery once preterm preeclampsia has been diagnosed, given the risk of developing maternal complications versus the risk of adverse perinatal outcomes associated with prematurity...
July 12, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28700503/mir-210-and-mir-155-as-potential-diagnostic-markers-for-pre-eclampsia-pregnancies
#18
Lu Gan, Zheng Liu, Ming Wei, Yulong Chen, Xiaomei Yang, Lihong Chen, Xiaomin Xiao
Pre-eclampsia (PE) is one of the leading causes of maternal and neonatal morbidity and mortality. In recent years, many studies have shown that microRNAs (miRNA) play important roles in the development of PE. However, the molecular pathogenesis of PE remains unknown.In the present study, we performed a case-control study to verify the differential expression of 4 candidate miRNAs (miR-210, miR-155, miR-125b-5p, and miR-125a-5p) in 20 PE pregnancies and 20 healthy pregnancies. The real-time quantitative reverse transcriptase-polymerase chain reaction has been utilized to estimate the Ct values in both groups...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28698073/does-a-body-mass-index-greater-than-25kg-m-2-increase-maternal-and-neonatal-morbidity-a-french-historical-cohort-study
#19
P Deruelle, E Servan-Schreiber, O Riviere, C Garabedian, F Vendittelli
OBJECTIVES: To evaluate, in a French multicenter cohort, the risk of C-section based on a high pre-pregnancy body mass index (BMI). Secondary objectives were to assess the risk of elective C-section, severe post-partum hemorrhage (>1L), severe perineal tears (3rd and 4th degree) and neonatal complications according to pre-pregnancy BMI. STUDY DESIGN: This historical cohort study analyzed records from the French AUDIPOG perinatal database. Inclusion criteria were deliveries≥22 weeks (or with a birth weight≥500g)...
July 8, 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28697534/consensus-bundle-on-severe-hypertension-during-pregnancy-and-the-postpartum-period
#20
Peter S Bernstein, James N Martin, John R Barton, Laurence E Shields, Maurice L Druzin, Barbara M Scavone, Jennifer Frost, Christine H Morton, Catherine Ruhl, Joan Slager, Eleni Z Tsigas, Sara Jaffer, M Kathryn Menard
Complications arising from hypertensive disorders of pregnancy are among the leading causes of preventable severe maternal morbidity and mortality. Timely and appropriate treatment has the potential to significantly reduce hypertension-related complications. To assist health care providers in achieving this goal, this patient safety bundle provides guidance to coordinate and standardize the care provided to women with severe hypertension during pregnancy and the postpartum period. This is one of several patient safety bundles developed by multidisciplinary work groups of the National Partnership for Maternal Safety under the guidance of the Council on Patient Safety in Women's Health Care...
July 11, 2017: Journal of Midwifery & Women's Health
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