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https://www.readbyqxmd.com/read/27915068/effects-of-the-pulsed-ultrasound-therapy-on-sensory-nerve-conduction-parameters-and-the-pain-threshold-perceptions-in-humans
#1
Othmar Schuhfried, Damir Vukanovic, Christian Kollmann, Karin Pieber, Tatjana Paternostro-Sluga
BACKGROUND: Therapeutic ultrasound is a often used clinical modality in the non-surgical treatment of entrapment neuropathies. To date the possible mechanism of action of pulsed ultrasound therapy on the peripheral nerve in the treatment of entrapment neuropathies is unclear. OBJECTIVE: To examine the effects of pulsed ultrasound therapy on peripheral nerve conduction parameters. DESIGN: A prospective, randomized, single blind, cross-over study...
November 30, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27912882/tenuifolin-a-saponin-derived-from-radix-polygalae-exhibits-sleep-enhancing-effects-in-mice
#2
Qing Cao, Yong Jiang, Su-Ying Cui, Peng-Fei Tu, Yue-Mei Chen, Xiao-Li Ma, Xiang-Yu Cui, Yuan-Li Huang, Hui Ding, Jin-Zhi Song, Bin Yu, Zhao-Fu Sheng, Zi-Jun Wang, Ya-Ping Xu, Guang Yang, Hui Ye, Xiao Hu, Yong-He Zhang
BACKGROUND: Radix Polygalae, the dried root of Polygala tenuifolia, has been extensively used as a traditional Chinese medicine for promoting intelligence and tranquilization. Polygalasaponins extracted from the root of P. tenuifolia possess evident anxiolytic and sedative-hypnotic activities. Previous studies have reported that tenuifolin was a major constituent of polygalasaponins. PURPOSE: The currently study aims to investigate the hypnotic effect and possible mechanism of tenuifolin in freely moving mice...
December 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27910516/plasma-rotation-in-the-peking-university-plasma-test-device
#3
Chijie Xiao, Yihang Chen, Xiaoyi Yang, Tianchao Xu, Long Wang, Min Xu, Dong Guo, Yi Yu, Chen Lin
Some preliminary results of plasma rotations in a linear plasma experiment device, Peking University Plasma Test (PPT) device, are reported in this paper. PPT has a cylindrical vacuum chamber with 500 mm diameter and 1000 mm length, and a pair of Helmholtz coils which can generate cylindrical or cusp magnetic geometry with magnitude from 0 to 2000 G. Plasma was generated by a helicon source and the typical density is about 10(13) cm(-3) for the argon plasma. Some Langmuir probes, magnetic probes, and one high-speed camera are set up to diagnose the rotational plasmas...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27909360/learning-curves-observed-in-establishing-targeted-rate-of-force-application-in-pressure-pain-algometry
#4
Alicia J Emerson Kavchak, Josiah D Sault, Ann Vendrely
Purpose: To determine whether learning curves can be observed with deliberate practice when the goal is to apply a consistent rate of force at 5 N/second during pressure pain threshold (PPT) testing in healthy volunteers. Methods: In this prospective study, 17 clinician participants completed PPT targeted rate-of-application testing with healthy volunteers using three different feedback paradigms. The resultant performances of ramp rate during 36 trials were plotted on a graph and examined to determine whether learning curves were observed...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27902566/conditioned-pain-modulation-in-non-specific-chronic-back-pain-patients-with-chronic-local-pain-chronic-widespread-pain-and-fibromyalgia
#5
Andreas Gerhardt, Wolfgang Eich, Rolf-Detlef Treede, Jonas Tesarz
Findings considering conditioned pain modulation (CPM) in chronic back pain (CBP) are contradictory. This might be because many CBP patients report pain in further areas of the body and altered CPM might influence spatial extent of pain rather than CBP per se. Therefore, we compared CPM in CBP patients with different pain extent. Fibromyalgia syndrome (FMS) patients, for whom CPM-impairment is reported most consistently, were measured for comparison.Based on clinical evaluation and pain-drawings patients were categorized into chronic local back pain (CLP; n=53), chronic widespread back pain (CWP; n=32), and FMS (n=92)...
November 28, 2016: Pain
https://www.readbyqxmd.com/read/27898461/cold-pain-threshold-identifies-a-subgroup-of-patients-with-knee-osteoarthritis-that-present-with-multimodality-hyperalgesia-and-elevated-pain-levels
#6
Anthony Wright, Heather A E Benson, Rob Will, Penny Moss
OBJECTIVES: Cold hyperalgesia has been established as an important marker of pain severity in a number of conditions. This study aimed to establish the extent to which patients with knee osteoarthritis (OA) demonstrate widespread cold, heat, and pressure hyperalgesia. OA participants with widespread cold hyperalgesia were compared with the remaining OA cohort to determine whether they could be distinguished in terms of hyperalgesia, pain report, pain quality, and physical function. METHODS: A total of 80 participants with knee OA and 40 matched healthy controls participated...
November 24, 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27896031/salinity-and-temperature-significantly-influence-seed-germination-seedling-establishment-and-seedling-growth-of-eelgrass-zostera-marina-l
#7
Shaochun Xu, Yi Zhou, Pengmei Wang, Feng Wang, Xiaomei Zhang, Ruiting Gu
Globally, seagrass beds have been recognized as critical yet declining coastal habitats. To mitigate seagrass losses, seagrass restorations have been conducted in worldwide over the past two decades. Seed utilization is considered to be an important approach in seagrass restoration efforts. In this study, we investigated the effects of salinity and temperature on seed germination, seedling establishment, and seedling growth of eelgrass Zostera marina L. (Swan Lake, northern China). We initially tested the effects of salinity (0, 5, 10, 15, 20, 25, 30, 35, and 40 ppt) and water temperature (5, 10, 15, and 20 °C) on seed germination to identify optimal levels...
2016: PeerJ
https://www.readbyqxmd.com/read/27886420/posterior-tibial-tendinopathy-associated-with-matrix-metalloproteinase-13-promoter-genotype-and-haplotype
#8
REVIEW
Francielle Boçon de Araujo Munhoz, José Eduardo Baroneza, Alexandre Godoy-Santos, Túlio Diniz Fernandes, Filipe Polese Branco, Lupe Furtado Alle, Ricardo Lehtonen de Souza, Maria Cristina Leme Godoy Dos Santos
BACKGROUND: Posterior tibial tendon (PTT) is particularly vulnerable and its insufficiency is recognized as the main cause of adult acquired flat foot. Some patients have a predisposition without clinically recognized cause, suggesting that individual characteristics play an important role in tendinopathy. Objective was investigated whether genetic variants in matrix metalloproteinases (MMPs) are associated with PTT dysfunction. METHODS: 100 women who presented PTT dysfunction, with histopathological examination of the tendon and magnetic resonance image (MRI) confirming tendinopathy, while 100 asymptomatic women who present intact PPT at MRI constituted the control group were evaluated for MMP-13 g...
November 25, 2016: Journal of Gene Medicine
https://www.readbyqxmd.com/read/27885640/differences-in-topographical-pressure-pain-sensitivity-maps-of-the-scalp-between-patients-with-migraine-and-healthy-controls
#9
Johanna Barón, Marina Ruiz, María Palacios-Ceña, Pascal Madeleine, Ángel L Guerrero, Lars Arendt-Nielsen, César Fernández-de-Las-Peñas
OBJECTIVE: To investigate differences in topographical pressure pain sensitivity maps of the scalp between patients with migraine and healthy controls considering the chronicity (episodic/chronic) and side (strictly unilateral/bilateral) of the symptoms. BACKGROUND: It seems that the trigeminal area is sensitized in migraine. No study has investigated topographical pressure sensitivity maps of the scalp in patients with migraine. METHODS: Pressure pain thresholds (PPTs) were assessed from 21 points distributed over the scalp in 86 patients with episodic migraine, 76 with chronic migraine, and 42 healthy age and matched healthy controls in a blinded design...
November 25, 2016: Headache
https://www.readbyqxmd.com/read/27884690/conditioned-pain-modulation-and-pressure-pain-sensitivity-in-the-adult-danish-general-population-the-danfund-study
#10
S Skovbjerg, T Jørgensen, L Arendt-Nielsen, J F Ebstrup, T Carstensen, T Graven-Nielsen
: Increased pressure pain sensitivity and impaired descending pain control have been associated with chronic pain, but knowledge on the variability in the adult general population is lacking. Pressure pain thresholds (PPTs) and descending pain control as assessed by conditioning pain modulation (CPM) were recorded in a randomly selected sample (n=2199, 53% females) of the Danish adult general population aged 18-70 years. PPTs were recorded over the tibialis anterior muscle and the upper trapezius muscle...
November 21, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27884526/impacts-of-changes-in-climate-and-landscape-pattern-on-ecosystem-services
#11
Ruifang Hao, Deyong Yu, Yupeng Liu, Yang Liu, Jianmin Qiao, Xue Wang, Jinshen Du
The restoration of degraded vegetation can effectively improve ecosystem services, increase human well-being, and promote regional sustainable development. Understanding the changing trends in ecosystem services and their drivers is an important step in informing decision makers for the development of reasonable landscape management measures. From 2001 to 2014, we analyzed the changing trends in five critical ecosystem services in the Xilingol Grassland, which is typical of grasslands in North China, including net primary productivity (NPP), soil conservation (SC), soil loss due to wind (SL), water yield (WY) and water retention (WR)...
November 22, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27876459/local-and-widespread-hyperalgesia-in-female-runners-with-patellofemoral-pain-are-influenced-by-running-volume
#12
Marcella Ferraz Pazzinatto, Danilo de Oliveira Silva, Juliana Pradela, Maira Bergamaschi Coura, Christian Barton, Fábio Mícolis de Azevedo
OBJECTIVES: To compare pressure pain threshold (PPT) around the knee (local hyperalgesia) and at a site remote to the knee (widespread hyperalgesia) between female runners with and without patellofemoral pain (PFP); and to evaluate the relationship between running volume, self-reported knee function and PPT measures. DESIGN: Cross-sectional study. METHODS: Twenty female runners with PFP and twenty pain-free female runners participated in the study...
November 11, 2016: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/27873118/current-update-of-a-carboxymethylcellulose-peg-conjugate-platform-for-delivery-of-insoluble-cytotoxic-agents-to-tumors
#13
Yang Yang, Joseph Bteich, Shyh-Dar Li
Cytotoxic chemotherapeutic agents are used as the standard therapy for a range of significant cancers, but many of these drugs suffer from poor water solubility and low selectivity, limiting their clinical efficacy. To overcome these shortcomings, Cellax™ drug delivery platform was developed. Cellax™ is a polymer-based nanoparticle drug delivery system designed to solubilize hydrophobic drugs and target them to solid tumors, thereby enhancing the efficacy and reducing the side effects. Cellax-docetaxel (Cellax-DTX) displayed improved pharmacokinetic, safety, and efficacy profiles compared to native DTX (Taxotere®) and Nab-paclitaxel (Nab-PTX, Abraxane®) in multiple animal models...
November 21, 2016: AAPS Journal
https://www.readbyqxmd.com/read/27872630/control-of-wilt-and-rot-pathogens-of-tomato-by-antagonistic-pink-pigmented-facultative-methylotrophic-delftia-lacustris-and-bacillus-spp
#14
Veeranan Janahiraman, Rangasamy Anandham, Soon W Kwon, Subbiah Sundaram, Veeranan Karthik Pandi, Ramasamy Krishnamoorthy, Kiyoon Kim, Sandipan Samaddar, Tongmin Sa
The studies on the biocontrol potential of pink pigmented facultative methylotrophic (PPFM) bacteria other than the genus Methylobacterium are scarce. In the present study, we report three facultative methylotrophic isolates; PPO-1, PPT-1, and PPB-1, respectively, identified as Delftia lacustris, Bacillus subtilis, and Bacillus cereus by 16S rRNA gene sequence analysis. Hemolytic activity was tested to investigate the potential pathogenicity of isolates to plants and humans, the results indicates that the isolates PPO-1, PPT-1, and PPB-1 are not pathogenic strains...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27867153/cultivating-the-scientific-research-ability-of-undergraduate-students-in-teaching-of-genetics
#15
Xing Wanjin, Morigen Morigen
The classroom is the main venue for undergraduate teaching. It is worth pondering how to cultivate undergraduate's research ability in classroom teaching. Here we introduce the practices and experiences in teaching reform in genetics for training the research quality of undergraduate students from six aspects: (1) constructing the framework for curriculum framework systematicaly, (2) using the teaching content to reflect research progress, (3) explaining knowledge points with research activities, (4) explaining the scientific principles and experiments with PPT animation, (5) improving English reading ability through bilingual teaching, and (6) testing students' analysing ability through examination...
November 20, 2016: Yi Chuan, Hereditas
https://www.readbyqxmd.com/read/27867056/manipulation-of-ph-sensitive-interactions-between-podophyllotoxin-chitosan-for-enhanced-controlled-drug-release
#16
Chao Chen, Yong Yu, Xiaoli Wang, Ping Shi, Yibing Wang, Ping Wang
Podophyllotoxin (PPT) offers a broad-spectrum of anticancer activities, but little has been reported for its controlled release. This work shows that by manipulating molecular interactions between PPT and Chitosan, efficient nanoscale capsulation of PPT can be realized. The drug encapsulation efficiency is as high as 52%, with a final particle drug loading in the order of 10% (wt/wt). It further demonstrates that changes in pH can also significantly affect the rate of drug release from the Chitosan nanoparticles...
November 17, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27863792/presence-of-latent-myofascial-trigger-points-and-determination-of-pressure-pain-thresholds-of-the-shoulder-girdle-in-healthy-children-and-young-adults-a-cross-sectional-study
#17
Luciane S Sacramento, Paula R Camargo, Aristides L Siqueira-Júnior, Jean P Ferreira, Tania F Salvini, Francisco Alburquerque-Sendín
OBJECTIVE: The primary objective of this study was to compare the number of myofascial trigger points (MTPs) and the pressure pain thresholds (PPTs) in the shoulder girdle, on the dominant and nondominant sides, between healthy children and adults. The secondary aim was to assess the correlations between the number of MTPs and the PPTs in these populations. METHODS: A cross-sectional study was performed. Thirty-five children (aged 9.1 ± 1.7 years) and 35 adults (aged 23...
November 15, 2016: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/27862644/bilateral-experimental-neck-pain-reorganize-axioscapular-muscle-coordination-and-pain-sensitivity
#18
S W Christensen, R P Hirata, T Graven-Nielsen
BACKGROUND: Neck pain is a large clinical problem where reorganized trunk and axioscapular muscle activities have been hypothesised contributing to pain persistence and pain hypersensitivity. This study investigated the effects of bilateral experimental neck pain on trunk and axioscapular muscle function and pain sensitivity. METHODS: In 25 healthy volunteers, bilateral experimental neck pain was induced in the splenius capitis muscles by hypertonic saline injections...
November 11, 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27859944/user-independent-assessment-of-conditioning-pain-modulation-by-cuff-pressure-algometry
#19
T Graven-Nielsen, M Izumi, K K Petersen, L Arendt-Nielsen
BACKGROUND: The use of conditioning pain modulation (CPM) is hampered by poor reproducibility and lack of user-independent paradigms. This study refined the CPM paradigm by applying user-independent cuff algometry. METHODS: In 20 subjects, the CPM effect of conditioning with cuff stimulation on the arm was investigated by pain test stimuli on the contralateral leg before and in parallel with different cuff conditionings (10, 30, 60 kPa/60 s; 30, 60 kPa/10 s)...
November 11, 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27857633/clinical-effectiveness-of-dry-needling-immediately-after-application-on-myofascial-trigger-point-in-upper-trapezius-muscle
#20
Maryam Ziaeifar, Amir Massoud Arab, Mohammad Reza Nourbakhsh
OBJECTIVE: The purpose of this study was to investigate the effect of dry needling (DN) on pain intensity and pressure pain threshold (PPT) compared with ischemic compression (IC) immediately and 48 hours after each treatment session in individuals with myofascial trigger points in the upper trapezius muscle. METHODS: Thirty-one patients with myofascial trigger points in the upper trapezius muscle participated in this study. Patients were randomly assigned to a standard (N = 17) or experimental group (N = 14)...
December 2016: Journal of Chiropractic Medicine
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