keyword
MENU ▼
Read by QxMD icon Read
search

PPT

keyword
https://www.readbyqxmd.com/read/28078340/biocompatible-cus-based-nanoplatforms-for-efficient-photothermal-therapy-and-chemotherapy-in-vivo
#1
Shuwen Peng, Yuanyuan He, Murat Er, Yuanzhi Sheng, Yueqing Gu, Haiyan Chen
Near-infrared (NIR) photothermal therapy (PTT) is a new approach to ablate cancer without affecting normal tissues. A pivotal concern of PPT is to develop photo-responsive agents with high biocompatibility as well as effective photothermal conversion efficiency. Copper sulfide (CuS) nanoparticles prepared are characterized by their low synthesis cost, wide NIR absorption range, good biocompatibility and favorable NIR photothermal conversion efficiency. CuS nanoparticles were then coated with mesoporous silicon dioxide (SiO2) by the Stober method, and further loaded with anticancer drug doxorubicin (DOX)...
January 12, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28068845/post-traumatic-growth-in-adult-survivors-of-brain-injury-a-qualitative-study-of-participants-completing-a-pilot-trial-of-brief-positive-psychotherapy
#2
Olga Karagiorgou, Jonathan J Evans, Breda Cullen
PURPOSE: Post-traumatic growth (PTG) can occur following acquired brain injury (ABI). It has been proposed that people experiencing psychological distress following ABI may benefit from a positive psychotherapy intervention (PPT) aimed at increasing well-being; PPT may also influence PTG. We aimed to investigate PTG experiences in participants of a positive psychotherapy pilot trial. METHODS: ABI survivors who had received PPT or treatment as usual (TAU) were interviewed individually after the end of the trial...
January 9, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28060194/chronic-lateral-epicondylalgia-does-not-exhibit-mechanical-pain-modulation-in-response-to-noxious-conditioning-heat-stimulus
#3
Edwin Choon Wyn Lim, Michele Sterling, Bill Vicenzino
The impaired attenuation of pain by the application of a noxious conditioning stimulus at a segmentally distinct site, known as conditioned pain modulation, has been implicated in clinical pain states. Chronic lateral epicondylalgia (LE), which is characterized by lower pressure pain thresholds at sites remote to the affected elbow and spinal cord hyperexcitability, is a clinical pain state that might plausibly involve less efficacious conditioned pain modulation. This study aimed to determine if LE exhibits a less efficacious conditioned pain modulation compared to healthy controls...
January 3, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28059472/promoting-active-learning-of-graduate-student-by-deep-reading-in-biochemistry-and-microbiology-pharmacy-curriculum
#4
Ren Peng
To promote graduate students' active learning, deep reading of high quality papers was done by graduate students enrolled in biochemistry and microbiology pharmacy curriculum offered by college of life science, Jiangxi Normal University from 2013 to 2015. The number of graduate students, who participated in the course in 2013, 2014, and 2015 were eleven, thirteen and fifteen, respectively. Through deep reading of papers, presentation, and group discussion in the lecture, these graduate students have improved their academic performances effectively, such as literature search, PPT document production, presentation management, specialty document reading, academic inquiry, and analytical and comprehensive ability...
January 6, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28054261/effectiveness-of-low-level-laser-therapy-on-pain-intensity-pressure-pain-threshold-and-sf-mpq-indexes-of-women-with-myofascial-pain
#5
Laís Valencise Magri, Vinícius Almeida Carvalho, Flávia Cássia Cabral Rodrigues, César Bataglion, Christie Ramos Andrade Leite-Panissi
Women with temporomandibular disorders (TMD) frequently report pain areas in body regions. This process is associated with central sensitization phenomena, present in chronic pain. The low-level laser therapy (LLLT) has been reported as a therapeutic option for the painful TMD treatment. The aim of this study was to analyze the effect of LLLT on pain intensity (visual analogue scale, VAS), pain sensitivity in orofacial and corporal points (pressure pain threshold, PPT), and on Short Form-McGill Pain Questionnaire (SF-MPQ) indexes of women with myofascial pain (subtype of muscle TMD)...
January 4, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28054105/comparative-developmental-toxicity-of-desalination-brine-and-sulfate-dominated-saltwater-in-a-euryhaline-fish
#6
Allison Kupsco, Rafid Sikder, Daniel Schlenk
Desalination is a promising sustainable solution to meet growing water needs of cities across the United States. However, the environmental impacts of the resulting filtrate (brine) discharged to surface water need to be evaluated before large-scale desalination can be successful in the United States. Developing fish are especially sensitive to changes in salinity and varying ionic composition. Limited research is available on the impacts of hypersalinity on chronic vertebrate embryonic development, particularly on sublethal effects...
January 4, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28053139/cuff-pressure-pain-detection-is-associated-with-both-sex-and-physical-activity-level-in-nonathletic-healthy-subjects
#7
Dag Lemming, Björn Börsbo, Anna Sjörs, Eva-Britt Lind, Lars Arendt-Nielsen, Thomas Graven-Nielsen, Björn Gerdle
: PURPOSE : The aim of this study was to evaluate pressure pain sensitivity on leg and arm in 98 healthy persons (50 women) using cuff algometry. Furthermore, associations with sex and physical activity level were investigated. METHOD:  Normal physical activity level was defined as Godin Leisure-Time Exercise Questionnaire (GLTEQ) score ≤ 45 and high activity level as GLTEQ > 45. A pneumatic double-chamber cuff was placed around the arm or leg where a single chamber was inflated...
January 4, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28052089/evaluation-of-pressure-pain-threshold-as-a-measure-of-perceived-stress-and-high-job-strain
#8
Lisbeth Hven, Poul Frost, Jens Peter Ellekilde Bonde
OBJECTIVE: To investigate whether pressure pain threshold (PPT), determined by pressure algometry, can be used as an objective measure of perceived stress and job strain. METHODS: We used cross-sectional base line data collected during 1994 to 1995 within the Project on Research and Intervention in Monotonous work (PRIM), which included 3123 employees from a variety of Danish companies. Questionnaire data included 18 items on stress symptoms, 23 items from the Karasek scale on job strain, and information on discomfort in specified anatomical regions was also collected...
2017: PloS One
https://www.readbyqxmd.com/read/28042685/lumbopelvic-core-stabilization-exercise-and-pain-modulation-among-individuals-with-chronic-nonspecific-low-back-pain
#9
Aatit Paungmali, Leonard H Joseph, Sitilertpisan Patraporn, Ubon Pirunsan, Sureeporn Uthaikhup
BACKGROUND: Lumbopelvic stabilization training (LPST) may provide therapeutic benefits on pain modulation in chronic nonspecific low back pain conditions. This study aimed to examine the effects of LPST on pain threshold and pain intensity in comparison to the passive automated cycling intervention and control intervention among patients with chronic nonspecific low back pain. METHODS: A within-subject, repeated-measures, crossover randomized controlled design was conducted among 25 participants (7 males and 18 females) with chronic nonspecific low back pain...
January 2, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28039375/cholinergic-glutamatergic-and-gabaergic-neurons-of-the-ppt-have-distinct-effects-on-sleep-wake-behavior-in-mice
#10
Daniel Kroeger, Loris L Ferrari, Gaetan Petit, Carrie E Mahoney, Patrick M Fuller, Elda Arrigoni, Thomas E Scammell
: The pedunculopontine tegmental nucleus (PPT) has long been implicated in the regulation of cortical activity and behavioral states, including rapid eye movement (REM) sleep. For example, electrical stimulation of the PPT region during sleep leads to rapid awakening, whereas lesions of the PPT in cats reduce REM sleep. Though these effects have been linked with the activity of cholinergic PPT neurons, the PPT also includes intermingled glutamatergic and GABAergic cell populations, and the precise roles of cholinergic, glutamatergic and GABAergic PPT cell groups in regulating cortical activity and behavioral state remains unknown...
December 30, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28034980/patients-with-concomitant-chronic-neck-pain-and-myofascial-pain-in-masticatory-muscles-have-more-widespread-pain-and-distal-hyperalgesia-than-patients-with-only-chronic-neck-pain
#11
Daniel Muñoz-García, Ibai Lopez-Uralde-Villanueva, Héctor Beltrán-Alacreu, Roy La Touche, Josué Fernández-Carnero
OBJECTIVE: Insufficient evidence exists to compare widespread pain (WP), pain sensibility, and psychological factors that occur in patients presenting with chronic neck pain (CNP) or a combination of temporomandibular disorder (TMD) and other complaints. The present study compared the pain sensibility and psychological factors of subjects with CNP with those with TMD + CNP. DESIGN: Cross-sectional study. SETTING: Local community. SUBJECTS: A nonprobabilistic convenience sample of 86 persons with CNP or TMD was recruited into three groups: CNP, TMD with myofascial pain in masticatory muscles with cocomitant CNP (TMD + CNP), and asymptomatic control groups consisted of 27, 29, and 30 participants, respectively...
December 29, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28032633/estrogen-receptors-%C3%AE-and-%C3%AE-play-major-roles-in-ethanol-evoked-myocardial-oxidative-stress-and-dysfunction-in-conscious-ovariectomized-rats
#12
Fanrong Yao, Abdel A Abdel-Rahman
BACKGROUND: We documented the dependence of ethanol (EtOH)-evoked myocardial dysfunction on estrogen (E2 ), and our recent estrogen receptor (ER) blockade study, in proestrus rats, implicated ERα signaling in this phenomenon. However, a limitation of selective pharmacological loss-of-function approach is the potential contribution of the other 2 ERs to the observed effects because crosstalk exists between the 3 ERs. Here, we adopted a "regain"-of-function approach (using selective ER subtype agonists) to identify the ER subtype(s) required for unraveling the E2 -dependent myocardial oxidative stress/dysfunction caused by EtOH in conscious ovariectomized (OVX) rats...
December 29, 2016: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28029783/platinum-coated-gold-nanorods-efficient-reactive-oxygen-scavengers-that-prevent-oxidative-damage-toward-healthy-untreated-cells-during-plasmonic-photothermal-therapy
#13
Mena Aioub, Sajanlal R Panikkanvalappil, Mostafa A El-Sayed
As a minimally invasive therapeutic strategy, gold nanorod (AuNR)-based plasmonic photothermal therapy (PPT) has shown significant promise for the selective ablation of cancer cells. However, the heat stress experienced by cells during the PPT treatment produces significant amounts of reactive oxygen species (ROS), which could harm healthy, untreated tissue near the point of care by inducing irreversible damage to DNA, lipids, and proteins, potentially causing cellular dysfunction or mutation. In this study, we utilized biocompatible Pt-coated AuNRs (PtAuNRs) with different platinum shell thicknesses as an alternative to AuNRs often used for the treatment...
January 3, 2017: ACS Nano
https://www.readbyqxmd.com/read/28027399/activation-of-bdnf-trkb-signaling-in-the-pedunculopontine-tegmental-nucleus-ppt-a-novel-mechanism-for-the-homeostatic-regulation-of-rem-sleep
#14
Abigail K Barnes, Richa Koul-Tiwari, Jennifer M Garner, Phillip A Geist, Subimal Datta
REM sleep dysregulation is a symptom of many neuropsychiatric disorders, yet the mechanisms of REM sleep homeostatic regulation are not fully understood. We have shown that, after REM sleep deprivation, the pedunculopontine tegmental nucleus (PPT) plays a critical role in the generation of recovery REM sleep. In the present study, we used multidisciplinary techniques to show a causal relationship between BDNF-TrkB signaling in the PPT and the development of REM sleep homeostatic drive. Rats were randomly assigned to conditions of unrestricted sleep or selective REM sleep deprivation (RSD) with PPT microinjections of vehicle control or a dose of a TrkB receptor inhibitor (2, 3, or 4 nmol K252a or 4 nmol ANA-12)...
December 27, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28025376/local-and-generalized-endogenous-pain-modulation-in-healthy-men-effects-of-exercise-and-exercise-induced-muscle-damage
#15
Christopher D Black, Brandon K Tynes, Alexander R Gonglach, Dwight E Waddell
: Isometric exercise has been shown to activate endogenous pain inhibitory pathways in healthy adults, but not in some clinical pain populations. OBJECTIVE:  Exercise-induced muscle damage (EIMD) and the associated delayed-onset muscle soreness (DOMS) are a model for studying clinical pain; thus, our purpose was to examine the effects of isometric exercise on pressure pain threshold (PPT) in the presence and absence of DOMS. METHODS:  Data were collected on 23 males (22...
December 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28017564/rapid-and-sensitive-analysis-of-polychlorinated-biphenyls-and-acrylamide-in-food-samples-using-ionic-liquid-based-in-situ-dispersive-liquid-liquid-microextraction-coupled-to-headspace-gas-chromatography
#16
Cheng Zhang, Cecilia Cagliero, Stephen A Pierson, Jared L Anderson
A simple and rapid ionic liquid (IL)-based in situ dispersive liquid-liquid microextraction (DLLME) method was developed and coupled to headspace gas chromatography (HS-GC) employing electron capture (ECD) and mass spectrometry (MS) detection for the analysis of polychlorinated biphenyls (PCBs) and acrylamide at trace levels from milk and coffee samples. The chemical structures of the halide-based ILs were tailored by introducing various functional groups to the cations to evaluate the effect of different structural features on the extraction efficiency of the target analytes...
December 8, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28013424/effects-of-different-salinities-on-growth-performance-survival-digestive-enzyme-activity-immune-response-and-muscle-fatty-acid-composition-in-juvenile-american-shad-alosa-sapidissima
#17
Zhi-Feng Liu, Xiao-Qiang Gao, Jiu-Xiang Yu, Xiao-Ming Qian, Guo-Ping Xue, Qiao-Yun Zhang, Bao-Liang Liu, Lei Hong
The effects of salinity on survival, growth, special activity of digestive enzymes, nonspecific immune response, and muscle fatty acid composition were evaluated in the American shad (Alosa sapidissima). Juveniles of 35 days after hatching were reared at 0 (control), 7, 14, 21, and 28 ppt for 60 days. At the end of the experiment, juvenile American shad presented higher survival and specific growth rate (SGR) in salinity group (7, 14, and 21 ppt) than control group (P < 0.05). The special activity of trypsin and chymotrypsin was highest in fish reared at 21 ppt, while the highest lipase special activity was obtained in control group (P < 0...
December 24, 2016: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28012221/transcriptomic-imprints-of-adaptation-to-fresh-water-parallel-evolution-of-osmoregulatory-gene-expression-in-the-alewife
#18
Jonathan P Velotta, Jill L Wegrzyn, Samuel Ginzburg, Lin Kang, Sergiusz Czesny, Rachel J O'Neill, Stephen D McCormick, Pawel Michalak, Eric T Schultz
Comparative approaches in physiological genomics offer an opportunity to understand the functional importance of genes involved in niche exploitation. We used populations of Alewife (Alosa pseudoharengus) to explore the transcriptional mechanisms that underlie adaptation to fresh water. Ancestrally anadromous Alewives have recently formed multiple, independently derived, landlocked populations, which exhibit reduced tolerance of saltwater and enhanced tolerance of fresh water. Using RNA-seq, we compared transcriptional responses of an anadromous Alewife population to two landlocked populations after acclimation to fresh (0 ppt)- and salt-water (35 ppt)...
December 24, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/28008644/test-retest-reliability-of-quantitative-sensory-testing-for-mechanical-somatosensory-and-pain-modulation-assessment-of-masticatory-structures
#19
Yuri M Costa, Orlando Morita-Neto, Everardo N S de Araújo-Júnior, Fernanda A Sampaio, Paulo César R Conti, Leonardo R Bonjardim
BACKGROUND: Assessing the reliability of medical measurements is a crucial step toward the elaboration of an applicable clinical instrument. There are few studies that evaluate the reliability of somatosensory assessment and pain modulation of masticatory structures. OBJECTIVES: To estimate the test-retest reliability, i.e., over time, of the mechanical somatosensory assessment of anterior temporalis, masseter and temporomandibular joint (TMJ) and the conditioned pain modulation (CPM) using the anterior temporalis as the test site...
December 23, 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28007924/impact-of-periodic-presumptive-treatment-for-bacterial-vaginosis-on-the-vaginal-microbiome-among-women-participating-in-the-preventing-vaginal-infections-trial
#20
Jennifer E Balkus, Sujatha Srinivasan, Omu Anzala, Joshua Kimani, Chloe Andac, Jane Schwebke, David N Fredricks, R Scott McClelland
BACKGROUND: Evidence suggests specific vaginal bacteria that are associated with bacterial vaginosis (BV) may increase risk of adverse health outcomes in women. Among women participating in a randomized trial, we assessed the effect of periodic presumptive treatment (PPT) on detection and concentrations of select vaginal bacteria. METHODS: HIV-uninfected, nonpregnant women from the US and Kenya received intravaginal metronidazole 750mg plus miconazole 200mg or placebo for 5 consecutive nights each month for 12 months...
December 22, 2016: Journal of Infectious Diseases
keyword
keyword
94332
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"