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https://www.readbyqxmd.com/read/29782537/changes-in-the-vibration-sensitivity-and-pressure-pain-thresholds-in-patients-with-burning-mouth-syndrome
#1
Brenda de Souza Moura, Natália Dos Reis Ferreira, Marcos F DosSantos, Maria Elisa Rangel Janini
OBJECTIVE: To investigate the presence of changes in vibration detection and pressure pain threshold in patients with burning-mouth syndrome (BMS). DESIGN OF THE STUDY: Case-control study. The sample was composed of 30 volunteers, 15 with BMS and 15 in the control group. The pressure-pain threshold (PPT) and vibration-detection threshold (VDT) were examined. The clinical evaluation was complemented with the McGill Pain Questionnaire (MPQ), Douleur Neuropathique 4 (DN4) and Beck Depression and Anxiety Inventories (BDI and BAI, respectively)...
2018: PloS One
https://www.readbyqxmd.com/read/29782181/effectiveness-of-an-osteopathic-abdominal-manual-intervention-in-pain-thresholds-lumbopelvic-mobility-and-posture-in-women-with-chronic-functional-constipation
#2
María José Martínez-Ochoa, Juan Carlos Fernández-Domínguez, Jose Miguel Morales-Asencio, Javier González-Iglesias, François Ricard, Ángel Oliva-Pascual-Vaca
OBJECTIVES: To assess the effect of an osteopathic abdominal manual intervention (AMI) on pressure pain thresholds (PPTs), mobility, hip flexibility, and posture in women with chronic functional constipation. DESIGN: Randomized, double-blind placebo-controlled trial. SETTING/LOCATION: Subjects were recruited for the study by referral from different gastroenterology outpatient clinics in the city of Madrid (Spain). SUBJECTS: Sixty-two patients suffering from chronic functional constipation according to the guidelines of the Congress of Rome III...
May 21, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29777953/ultrasound-guided-application-of-percutaneous-electrolysis-as-an-adjunct-to-exercise-and-manual-therapy-for-subacromial-pain-syndrome-a-randomized-clinical-trial
#3
Lorena de-Miguel-Valtierra, Jaime Salom-Moreno, César Fernández-de-Las-Peñas, Joshua A Cleland, José L Arias-Buría
This randomized clinical trial compared the effects of adding US-guided percutaneous electrolysis into a program consisting of manual therapy and exercise on pain, related-disability, function and pressure sensitivity in subacromial pain syndrome. Fifty patients with subacromial pain syndrome were randomized into manual therapy and exercise or percutaneous electrolysis group. All patients received the same manual therapy and exercise program, one session per week for 5 consecutive weeks. Patients assigned to the electrolysis group also received the application of percutaneous electrolysis at each session...
May 16, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29777951/experimental-referred-pain-extends-towards-previously-injured-location-an-explorative-study
#4
Thorvaldur Skuli Palsson, Shellie A Boudreau, Hans Jørgen Krebs, Thomas Graven-Nielsen
Facilitated pain mechanisms have been demonstrated in musculoskeletal pain but it is unclear whether a recent painful injury leaves the pain system sensitized. Pain characteristics were assessed in individuals who recently recovered from ankle pain (recovered pain group; n=25) and sex-matched controls (n=25) in response to tonic-pressure pain and saline-induced pain applied at the shin muscle. Pain intensity and pain referral patterns were recorded bilaterally after the painful muscle stimulus. Pressure pain thresholds (PPTs) were measured at the lower legs and shoulder...
May 16, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29771988/variables-associated-with-sleep-quality-in-chronic-tension-type-headache-a-cross-sectional-and-longitudinal-design
#5
Elena Benito-González, Maria Palacios-Ceña, Juan J Fernández-Muñoz, Matteo Castaldo, Kelun Wang, Antonella Catena, Lars Arendt-Nielsen, César Fernández-de-Las-Peñas
OBJECTIVE: To investigate variables associated at baseline (cross-sectional design) and at one year (longitudinal design) with the quality of sleep in chronic tension-type headache (CTTH). METHODS: One hundred and eighty (n = 180) and 135 individuals with CTTH participated in the cross-sectional and longitudinal design respectively. Clinical features were collected with a 4-weeks headache diary at baseline and one-year follow-up. Sleep quality was assessed at baseline and 1-year follow-up with the Pittsburgh Sleep Quality Index...
2018: PloS One
https://www.readbyqxmd.com/read/29771165/cluster-subgroups-based-on-overall-pressure-pain-sensitivity-and-psychosocial-factors-in-chronic-musculoskeletal-pain-differences-in-clinical-outcomes
#6
Suzana C Almeida, Steven Z George, Raquel D V Leite, Anamaria S Oliveira, Thais C Chaves
OBJECTIVE: We aimed to empirically derive psychosocial and pain sensitivity subgroups using cluster analysis within a sample of individuals with chronic musculoskeletal pain (CMP) and to investigate derived subgroups for differences in pain and disability outcomes. METHODS: Eighty female participants with CMP answered psychosocial and disability scales and were assessed for pressure pain sensitivity. A cluster analysis was used to derive subgroups, and analysis of variance (ANOVA) was used to investigate differences between subgroups...
May 17, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29767650/immediate-effect-of-continuous-ultrasound-vs-sham-ultrasound-for-bilateral-masseter-myalgia-a-double-blinded-trial
#7
Haseeb Hussain, Heidi Crow, Yoly Gonzalez, W D McCall
AIMS: To investigate the local and segmental effects of therapeutic ultrasound at a dose of 0.4 w/cm2 with 100% duty cycle for 5 minutes compared to the effect of sham ultrasound on painful masticatory muscles. METHODS: A total of 20 adult female subjects with bilateral masseter myalgia diagnosed according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) were included. Each subject was randomized to either an active ultrasound group or a sham ultrasound group...
May 15, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29767649/experimental-psychological-stress-on-quantitative-sensory-testing-response-in-patients-with-temporomandibular-disorders
#8
Dyna Mara Araújo Oliveira Ferreira, Yuri Martins Costa, Henrique Müller de Quevedo, Leonardo Rigoldi Bonjardim, Paulo César Rodrigues Conti
AIMS: To assess the modulatory effects of experimental psychological stress on the somatosensory evaluation of myofascial temporomandibular disorder (TMD) patients. METHODS: A total of 20 women with myofascial TMD and 20 age-matched healthy women were assessed by means of a standardized battery of quantitative sensory testing. Cold detection threshold (CDT), warm detection threshold (WDT), cold pain threshold (CPT), heat pain threshold (HPT), mechanical pain threshold (MPT), wind-up ratio (WUR), and pressure pain threshold (PPT) were performed on the facial skin overlying the masseter muscle...
May 15, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29765322/therapeutic-potential-of-ginsenosides-as-an-adjuvant-treatment-for-diabetes
#9
REVIEW
Litao Bai, Jialiang Gao, Fan Wei, Jing Zhao, Danwei Wang, Junping Wei
Ginseng, one of the oldest traditional Chinese medicinal herbs, has been used widely in China and Asia for thousands of years. Ginsenosides extracted from ginseng, which is derived from the roots and rhizomes of Panax ginseng C. A. Meyer, have been used in China as an adjuvant in the treatment of diabetes mellitus. Owing to the technical complexity of ginsenoside production, the total ginsenosides are generally extracted. Accumulating evidence has shown that ginsenosides exert antidiabetic effects. In vivo and in vitro tests revealed the potential of ginsenoside Rg1, Rg3, Rg5, Rb1, Rb2, Rb3, compound K, Rk1, Re, ginseng total saponins, malonyl ginsenosides, Rd, Rh2, F2, protopanaxadiol (PPD) and protopanaxatriol (PPT)-type saponins to treat diabetes and its complications, including type 1 diabetes mellitus, type 2 diabetes mellitus, diabetic nephropathy, diabetic cognitive dysfunction, type 2 diabetes mellitus with fatty liver disease, diabetic cerebral infarction, diabetic cardiomyopathy, and diabetic erectile dysfunction...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29764452/risk-factors-for-korean-women-to-develop-an-isthmocele-after-a-cesarean-section
#10
I Y Park, M R Kim, H N Lee, Y Gen, M J Kim
BACKGROUND: The increase in number of cesarean section (CS) operations has resulted in an increase in cases of isthmocele development. The objective of this study is to determine the risk factors for isthmocele development after CS. METHODS: Isthmocele measurements were taken for 404 women with a history of at least one low transverse CS. The following potential risk factors were investigated: patient's age at CS, cause of CS, weeks of gestation at CS, premature rupture of membrane (PROM), phase of labor, type suture (single/double layer), operation time, uterine flexion (anteversion/retroversion), and blood transfusion during operation...
May 15, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29762685/urine-multi-drug-screening-with-gc-ms-or-lc-ms-ms-using-salle-hybrid-ppt-spe
#11
Junhui Lee, Jiwon Park, Ahra Go, Heesung Moon, Sujin Kim, Sohee Jung, Wonjoon Jeong, Heesun Chung
To intoxicated patients in the emergency room, toxicological analysis can be considerably helpful for identifying the involved toxicants. In order to develop a urine multi-drug screening (UmDS) method, gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS-MS) were used to determine targeted and unknown toxicants in urine. A GC-MS method in scan mode was validated for selectivity, limit of detection (LOD) and recovery. An LC-MS-MS multiple reaction monitoring (MRM) method was validated for lower LOD, recovery and matrix effect...
May 14, 2018: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/29760378/the-ginsenoside-ppd-exerts-anti-endometriosis-effects-by-suppressing-estrogen-receptor-mediated-inhibition-of-endometrial-stromal-cell-autophagy-and-nk-cell-cytotoxicity
#12
Bing Zhang, Wen-Jie Zhou, Chun-Jie Gu, Ke Wu, Hui-Li Yang, Jie Mei, Jia-Jun Yu, Xiao-Fan Hou, Jian-Song Sun, Feng-Yuan Xu, Da-Jin Li, Li-Ping Jin, Ming-Qing Li
Endometriosis (EMS) is an estrogen-dependent gynecological disease with a low autophagy level of ectopic endometrial stromal cells (eESCs). Impaired NK cell cytotoxic activity is involved in the clearance obstruction of the ectopic endometrial tissue in the abdominopelvic cavity. Protopanaxadiol (PPD) and protopanaxatriol (PPT) are two metabolites of ginsenosides, which have profound biological functions, such as anti-cancer activities. However, the role and mechanism of ginsenosides and metabolites in endometriosis are completely unknown...
May 14, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29757826/physical-activity-levels-predict-exercise-induced-hypoalgesia-in-older-adults
#13
Thomas Ohlman, Leah Miller, Keith E Naugle, Kelly M Naugle
Prior research indicates that older adults exhibit a deficient capacity to activate multiple pain inhibitory mechanisms, including pain inhibition after acute exercise termed exercise-induced hypoalgesia (EIH). The influence of physical activity levels and psychological processes on EIH in older adults remains unclear. PURPOSE: This study examined potential psychological and physical activity predictors of the magnitude of EIH following submaximal isometric exercise in healthy older adult men and women...
May 4, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29751194/the-central-sensitization-inventory-and-pain-sensitivity-questionnaire-an-exploration-of-construct-validity-and-associations-with-widespread-pain-sensitivity-among-individuals-with-shoulder-pain
#14
Rogelio A Coronado, Steven Z George
BACKGROUND: The Central Sensitization Inventory (CSI) and Pain Sensitivity Questionnaire (PSQ) are alternatives to quantitative sensory testing (QST) for inferring central sensitization. OBJECTIVE: Explore 1) comparative validity of the CSI and PSQ with QST (construct validity) and pain-related psychological questionnaires (concurrent validity), and 2) associations with widespread pain sensitivity. METHODS: Seventy-eight participants with unilateral shoulder pain less than 6 months (mean ± SD age = 39...
May 3, 2018: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/29746993/combination-of-exercise-and-acupuncture-vs-acupuncture-alone-for-treatment-of-myofascial-pain-syndrome-a-randomized-clinical-trial
#15
Bina Eftekharsadat, Elmira Porjafar, Fariba Eslamian, Seyed Kazem Shakouri, Hamid Reza Fadavi, Seyed Ahmad Raeissadat, Arash Babaei-Ghazani
Myofascial pain syndrome (MPS) is a common musculoskeletal disorder. This study was designed to compare the effects of aerobic exercise plus acupuncture with acupuncture alone in treatment of patients with MPS. Sixty four patients (55 female and 9 male) with myofascial pain syndrome in their neck and shoulders participated in the study with mean age of 33.1± 6.4. Participants were randomly allocated to aerobic exercise plus acupuncture (n = 32) or acupuncture alone (n = 32) groups. Outcome measurements included Visual Analog Scale (VAS), Pressure Pain Threshold (PPT), Neck Disability Index (NDI) and Quality of Life which was measured with QoL-SF36 scale...
May 7, 2018: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/29738892/effect-of-short-term-cold-water-immersion-on-muscle-pain-sensitivity-in-elite-track-cyclists
#16
Sebastian Klich, Igor Krymski, Kamil Michalik, Adam Kawczyński
OBJECTIVE: To determine the effect of short-term cold-water immersion (CWI) on muscle pain sensitivity after maximal anaerobic power training in track cyclists. DESIGN: Repeated measures. SETTING: University Laboratory. PARTICIPANTS: 12 elite sprint track cyclists (age 24,75 ± 4,23 years). MAIN OUTCOME MEASURES: PPT measurements were made on dominant lower extremity (right) in 20 reference points, including anterior thigh muscles, posterior thigh muscles and posterior cuff muscles...
May 1, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29733117/incorporation-of-photobiomodulation-therapy-into-a-therapeutic-exercise-program-for-knee-osteoarthritis-a-placebo-controlled-randomized-clinical-trial
#17
Cid A F de Paula Gomes, Ernesto C P Leal-Junior, Almir V Dibai-Filho, Adriano R de Oliveira, André S Bley, Daniela A Biasotto-Gonzalez, Paulo de Tarso Camillo de Carvalho
OBJECTIVE: To investigate the clinical effects of incorporation of phototherapy in a therapeutic exercise program for individuals with knee osteoarthritis (OA) when compared to a group that received exercise alone and to a group that received exercise + placebo phototherapy. MATERIALS AND METHODS: This is a randomized, blinded and placebo-controlled trial. Thus, sixty male and female individuals aged 40-80 years with knee pain in the previous 6 months participated of the study, with diagnosis of unilateral knee OA based on the criteria established by the American College of Rheumatology and radiographic confirmation and Grades 2 or 3 of the Kellgren-Lawrence Classification...
May 7, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29730170/the-antidepressant-effects-of-rosiglitazone-on-rats-with-depression-induced-by-neuropathic-pain
#18
Jian Zong, Xingzhi Liao, Bingxu Ren, Zhiping Wang
A growing number of studies reported that rosiglitazone (a PPARgamma agonist) could ameliorate the painful state and prevent stress-induced depression. However, whether rosiglitazone can prevent pain-induced depression is unclear. This study aimed to explore the antidepressant effects of rosiglitazone in L5 spinal nerve transection (SNT) induced neuropathic pain rats. In addition, AMPK inhibitor (Compound C) and autophagic antagonist (3-methyladenine, 3-MA) were applied to investigate the underlying therapeutic mechanisms...
May 3, 2018: Life Sciences
https://www.readbyqxmd.com/read/29727907/pancreatic-beta-cell-proliferation-induced-by-estradiol-17%C3%AE-is-foxo1-dependent
#19
Sigal Shaklai, Meital Grafi-Cohen, Orli Sharon, Nadav Sagiv, Gabi Shefer, Dalia Somjen, Naftali Stern
Estradiol-17β (E2) and the Foxo1 transcription factor have each been implicated in the regulation of β-cell proliferation. Interaction between Foxo1and estrogen receptor alpha (ERα), effecting cell cycle, has been demonstrated in breast cancer cells, but has not been studied thus far in β-cells. Using human islets and the INS1-E β-cell line, this study investigated the contribution of Foxo1 to E2-mediated β-cell replication. Foxo1 expression was knocked down in INS1-E cells using siRNA and Foxo1 activity was inhibited in human islets with a specific Foxo1 inhibitor (AS1842856)...
May 4, 2018: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29727811/development-and-psychometric-evaluation-of-the-pornography-purchase-task
#20
Kyler Mulhauser, Emily Miller Short, Jeremiah Weinstock
Excessive pornography use and hypersexuality are frequently evaluated via direct self-report of problem severity and negative consequences associated with these behaviors. These face-valid assessments may be less sensitive to problems of hypersexuality in persons with low insight into their condition or in persons with motivation to minimize the negative impact of their pornography use. Demand for addictive substances has been effectively evaluated through a behavioral economic framework using a hypothetical purchase task, in which respondents are asked to report their degree of engagement with the substance as the financial costs associated with use increase...
April 26, 2018: Addictive Behaviors
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