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https://www.readbyqxmd.com/read/29921192/decoding-new-york-state-s-prescription-monitoring-program
#1
Sanya Virani, Elie G Aoun, Nicholas Genova, Navjot Brainch, Camila Albuquerque Gomes, Saeed Ahmed, Brian Hurley, Lama Bazzi
This column describes the Internet System for Tracking Over-Prescribing (I-STOP), New York State's prescription monitoring program, and its compatibility with HIPAA and Part 2 of Volume 42 of the Code of Federal Regulations (CFR). The authors review use of information that is permitted by I-STOP and CFR for health care operations, including disclosure, and present information from the state Bureau of Narcotics Enforcement about appropriate use of the program. Physicians are permitted, for example, to contact other prescribers in I-STOP, even without explicit permission from the patient, an area in which physicians need more training...
June 20, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29730002/protective-and-antioxidative-effect-of-rubropunctatin-against-oxidative-protein-damage-induced-by-metal-catalyzed-reaction
#2
Mohan A Dhale, Manjunatha Javagal, Mohan-Kumari H Puttananjaiah
Monascus purpureus is known to produce several coloured secondary metabolites. In this study, M. purpureus CFR 410-11 mutant fermented with rice was dried and extracted in hexane for purification of pigment. The purity of the isolated pigment was confirmed by different chromatography techniques. The spectroscopic analysis revealed its structural identity as rubropunctatin. The antioxidant potencies of isolated rubropunctatin were evaluated. Rubropunctatin scavenged 16% 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical and inhibited 20% superoxide generation at 8 μg/ml concentration...
May 3, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29659858/zaaps-programme-results-for-2016-an-activity-and-spectrum-analysis-of-linezolid-using-clinical-isolates-from-medical-centres-in-42-countries
#3
Rodrigo E Mendes, Lalitagauri Deshpande, Jennifer M Streit, Helio S Sader, Mariana Castanheira, Patricia A Hogan, Robert K Flamm
Objectives: To report the linezolid activity, resistance mechanisms and epidemiological typing of selected isolates observed during the 2016 Zyvox® Annual Appraisal of Potency and Spectrum (ZAAPS) programme. Methods: A total of 8325 organisms were consecutively collected from 76 centres in 42 countries (excluding the USA). Broth microdilution susceptibility testing was performed and isolates displaying linezolid MICs of ≥4 mg/L were molecularly characterized...
April 6, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29657049/prognostic-implication-of-thermodilution-coronary-flow-reserve-in-patients-with-indeterminate-pressure-bounded-coronary-flow-reserve
#4
Joo Myung Lee, Tae-Min Rhee, Doyeon Hwang, Jonghanne Park, Chee Hae Kim, Ki Hong Choi, Eun-Seok Shin, Chang-Wook Nam, Joon-Hyung Doh, Bon-Kwon Koo
BACKGROUND: Recently, the concept of pressure-bounded coronary flow reserve (PB-CFR) has been introduced. However, using pressure-only data, a substantial proportion of patients could not be classified into high or low PB-CFR and remained as indeterminate PB-CFR. The current study evaluated the prognostic implication of thermodilution-based CFR (thermo-CFR) in patients with indeterminate PB-CFR. METHODS: Among 199 patients (211 lesions) with indeterminate PB-CFR, 170 patients (179 lesions) with deferral of revascularization were analyzed for the current study...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29425834/population-pharmacokinetics-pharmacodynamics-of-linezolid-in-sepsis-patients-with-and-without-continuous-renal-replacement-therapy
#5
Takeshi Ide, Yoshio Takesue, Kazuro Ikawa, Norifumi Morikawa, Takashi Ueda, Yoshiko Takahashi, Kazuhiko Nakajima, Kenta Takeda, Shinichi Nishi
PURPOSE: The purpose of this study was to identify the optimum dosing regimen of linezolid in sepsis patients with and without renal dysfunction and sepsis patients on low-dose continuous renal replacement therapy (CRRT) using a pharmacokinetics/pharmacokinetics (PK/PD) approach. METHODS: Sepsis patients with and without renal dysfunction (creatinine clearance < 50 mL/min), and sepsis patients on low-dose CRRT (dose: 800 mL/h) were studied. The PK data were modeled using a two-compartment model, and then used for simulation...
February 6, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29118655/the-burden-of-dengue-source-reduction-measures-and-serotype-patterns-in-myanmar-2011-to-2015-r2
#6
Pwint Mon Oo, Khin Thet Wai, Anthony D Harries, Hemant Deepak Shewade, Tin Oo, Aung Thi, Zaw Lin
Background: Myanmar is currently classified as a high burden dengue country in the Asian Pacific region. The Myanmar vector-borne diseases control (VBDC) program has collected data on dengue and source reduction measures since 1970, and there is a pressing need to collate, analyze, and interpret this information. The aim of this study was to describe the burden of hospital-based dengue disease, dengue control measures, and serotype patterns in Myanmar between 2011 and 2015. Methods: This was a cross-sectional study using annual records from the Dengue Fever/Dengue Hemorrhagic Fever Prevention and Control Project in Myanmar...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/29069202/association-of-inflammation-and-endothelial-dysfunction-with-coronary-microvascular-resistance-in-patients-with-cardiac-syndrome-x
#7
Ming Long, Zhibin Huang, Xiaodong Zhuang, Zena Huang, Yue Guo, Xinxue Liao, Chufan Luo
BACKGROUND: Although a proportion of CSX patients have impaired brachial artery flow-mediated dilatation (FMD) in response to hyperemia, suggesting that endothelial dysfunction in these patients may be systemic and not just confined to the coronary circulation; the underlying mechanisms triggering endothelial dysfunction in these patients are still incompletely understood. OBJECTIVES: To assess the association of the index of Microcirculatory Resistance (IMR) with endothelial dysfunction and inflammation in patients with CSX...
November 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29023038/evaluation-of-autothermal-thermophilic-aerobic-digester-performance-for-the-stabilization-of-municipal-wastewater-sludge
#8
Reza Shokoohi, Alireza Rahmani, Ghorban Asgari, Abdollah Dargahi, Yaser Vaziri, Mohammad Attar Abbasi
BACKGROUND AND OBJECTIVE: Sludge stabilization process in terms of operational, environmental and economic indexes is the most important stage of treatment and its disposal. This study was aimed to determine the performance of Autothermal Thermophilic Aerobic Digestion (ATAD) system as one of the low-cost and biocompatible methods of sludge treatment. MATERIALS AND METHODS: This study has been done using a laboratory scale Autothermal Thermophilic Aerobic Digestion (ATAD)...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/28699843/social-workers-have-an-obligation-to-all-patients-regarding-confidentiality-%C3%A2-however-for-some-patients-the-obligation-is-greater
#9
Karlynn BrintzenhofeSzoc, Caitlyn Gilbert
Social workers are held to many ethical obligations regarding patients including maintaining patient confidentiality and staying up to date on confidentiality laws, statutes, and regulations. As the landscape of health care continues to change, including the increased use of technology to maintain patient records, highlights this need. The changes in the regulations on confidentiality of those who are receiving substance use treatment, 42 CFR Part 2, are presented. The other regulations and laws covered include HIPAA, HITECH, and the ACA...
July 12, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28574240/medicare-program-advancing-care-coordination-through-episode-payment-models-epms-cardiac-rehabilitation-incentive-payment-model-and-changes-to-the-comprehensive-care-for-joint-replacement-model-cjr-delay-of-effective-date-final-rule-delay-of-effective-date
#10
(no author information available yet)
This final rule finalizes May 20, 2017 as the effective date of the final rule titled "Advancing Care Coordination Through Episode Payment Models (EPMs); Cardiac Rehabilitation Incentive Payment Model; and Changes to the Comprehensive Care for Joint Replacement Model (CJR)" originally published in the January 3, 2017 Federal Register. This final rule also finalizes a delay of the applicability date of the regulations at 42 CFR part 512 from July 1, 2017 to January 1, 2018 and delays the effective date of the specific CJR regulations listed in the DATES section from July 1, 2017 to January 1, 2018...
May 19, 2017: Federal Register
https://www.readbyqxmd.com/read/28432157/effect-of-interleukin-6-inhibition-on-coronary-microvascular-and-endothelial-function-in-myocardial-infarction
#11
RANDOMIZED CONTROLLED TRIAL
Espen Holte, Ola Kleveland, Thor Ueland, Gabor Kunszt, Marte Bratlie, Kaspar Broch, Annika E Michelsen, Bjørn Bendz, Brage H Amundsen, Svend Aakhus, Jan Kristian Damås, Lars Gullestad, Pål Aukrust, Rune Wiseth
OBJECTIVE: Interleukin-6 (IL-6) is a driver of inflammation and associated endothelial cell activation in acute coronary syndromes. We evaluated the effect of the IL-6 receptor antagonist tocilizumab on coronary microvascular function and endothelial dysfunction measured by coronary flow reserve (CFR) and markers of endothelial cell activation in patients with non-ST-elevation myocardial infarction (NSTEMI). METHODS: This substudy was part of a two-centre, double-blind, randomised, placebo-controlled trial evaluating the effect of a single dose of tocilizumab in NSTEMI...
October 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28378162/coronary-flow-reserve-in-mitral-stenosis-before-and-after-percutaneous-balloon-mitral-valvuloplasty
#12
Ragab A Mahfouz, Mohammad Gouda, Waleed Elawdy, Ashraf Dewedar
We aimed to evaluate the coronary flow reserve (CFR) before and after percutaneous balloon mitral valvuloplasty (PBMV) in patients with mitral stenosis (MS) and its association to clinical events. A prospective study included 45 patients with mitral stenosis candidate for PBMV (age 38 ± 19 years, 27 were females) and 20 with matched age and sex, healthy controls were included in the study. Noninvasive CFR was measured using transthoracic echocardiography and utilizing adenosine stress echocardiography (0...
September 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28273867/comparative-epidemiology-of-human-fatal-infections-with-novel-high-h5n6-and-h5n1-and-low-h7n9-and-h9n2-pathogenicity-avian-influenza-a-viruses
#13
Zu-Qun Wu, Yi Zhang, Na Zhao, Zhao Yu, Hao Pan, Ta-Chien Chan, Zhi-Ruo Zhang, She-Lan Liu
This study aimed to assess the mortality risks for human infection with high (HPAI) and low (LPAI) pathogenicity avian influenza viruses. The HPAI case fatality rate (CFR) was far higher than the LPAI CFR [66.0% (293/444) vs. 68.75% (11/16) vs. 40.4% (265/656) vs. 0.0% (0/18) in the cases with H5N1, H5N6, H7N9, and H9N2 viruses, respectively; p < 0.001]. Similarly, the CFR of the index cases was greater than the secondary cases with H5N1 [100% (43/43) vs. 43.3% (42/97), p < 0.001]. Old age [22.5 vs. 17 years for H5N1, p = 0...
March 4, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28219136/-an-epidemiological-investigation-of-pediatric-patients-under-14-with-large-area-burns-a-multicenter-study
#14
W F Cheng, D X Zhao, Z A Shen, H Y Zhang, J J Tu, Z Q Yuan, P Duan, G D Song
Objective: To investigate and evaluate the epidemiological characteristics of patients under 14 with large area burns in China. Methods: Data of pediatric patients aged 0-14yr with ≥30% total body surface area (TBSA) burned admitted into 106 burn centers in the mainland of China in 2014 were retrieved. The children were divided into three age groups: 0-3, 4-6 and 7-14 years according to the age. Information of age, gender, time of burn injury, causes of burns, admission time, prehospital emergency care of burn wound, burn area, inhalation injuries, the case fatality rate and length of hospital stay were collected for analysis...
February 14, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28160262/comparison-between-the-summed-difference-score-and-myocardial-blood-flow-measured-by-13-n-ammonia
#15
Raffaele Giubbini, Alessia Peli, Elisa Milan, Roberto Sciagrà, Luca Camoni, Domenico Albano, Mattia Bertoli, Mattia Bonacina, Federica Motta, Massimo Statuto, Carlo Alberto Rodella, Antonio De Agostini, Raffaella Calabretta, Francesco Bertagna
BACKGROUND: Both the myocardial perfusion pattern and myocardial blood flow (MBF) are used to assess patients with suspected coronary artery disease (CAD). The aim of this study was to compare the perfusion pattern (using the summed difference score [SDS]) to MBF in a consecutive group of patients undergoing PET/CT with 13 N-ammonia (13 NH3 ). METHODS: 47 consecutive patients, aged 65 ± 12 years (42 men) with known or suspected CAD, underwent vasodilator stress/rest PET/CT with 13 NH3 for clinical indications...
February 3, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27799017/the-perceived-impact-of-42-cfr-part-2-on-coordination-and-integration-of-care-a-qualitative-analysis
#16
Dennis McCarty, Traci Rieckmann, Robin L Baker, K John McConnell
OBJECTIVE: Title 42 of the Code of Federal Regulations Part 2 (42 CFR Part 2) controls the release of patient information about treatment for substance use disorders. In 2016, the Substance Abuse and Mental Health Services Administration (SAMHSA) released a proposed rule to update the regulations, reduce provider burdens, and facilitate information exchange. Oregon's Medicaid program (Oregon Health Plan) altered the financing and structure of medical, dental, and behavioral care to promote greater integration and coordination...
March 1, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/27540979/a-comparison-of-facemask-and-respirator-filtration-test-methods
#17
COMPARATIVE STUDY
Samy Rengasamy, Ronald Shaffer, Brandon Williams, Sarah Smit
NIOSH published a Federal Register Notice to explore the possibility of incorporating FDA required filtration tests for surgical masks (SMs) in the 42 CFR Part 84 respirator certification process. There have been no published studies comparing the filtration efficiency test methods used for NIOSH certification of N95 filtering facepiece respirators (N95 FFRs) with those used by the FDA for clearance of SMs. To address this issue, filtration efficiencies of "N95 FFRs" including six N95 FFR models and three surgical N95 FFR models, and three SM models were measured using the NIOSH NaCl aerosol test method, and FDA required particulate filtration efficiency (PFE) and bacterial filtration efficiency (BFE) methods, and viral filtration efficiency (VFE) method...
February 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/27456069/declining-incidence-of-intracerebral-hemorrhage-over-two-decades-in-a-population-based-study
#18
S Sacco, R Ornello, D Degan, C Tiseo, F Pistoia, A Carolei
BACKGROUND AND PURPOSE: The incidence and case-fatality rate (CFR) of primary intracerebral hemorrhage (PICH) over two decades were assessed in a prospective population-based study. METHODS: Cases of incident first-ever PICH were recorded over a 2-year period (2011-2012) from multiple sources in the district of L'Aquila, central Italy. Included patients were followed up to 1 year after the event to ascertain CFRs. Current data were compared with those previously collected from 1994 through 1998...
November 2016: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27328564/proposed-hhs-rule-could-modernize-42-cfr-part-2-at-last
#19
Donna Marbury
No abstract text is available yet for this article.
2016: Behavioral Healthcare
https://www.readbyqxmd.com/read/27146399/middle-east-respiratory-syndrome-coronavirus-current-situation-and-travel-associated-concerns
#20
REVIEW
Jaffar A Al-Tawfiq, Ali S Omrani, Ziad A Memish
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 brought back memories of the occurrence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002. More than 1500 MERS-CoV cases were recorded in 42 months with a case fatality rate (CFR) of 40%. Meanwhile, 8000 cases of SARS-CoV were confirmed in six months with a CFR of 10%. The clinical presentation of MERS-CoV ranges from mild and non-specific presentation to progressive and severe pneumonia. No predictive signs or symptoms exist to differentiate MERS-CoV from community-acquired pneumonia in hospitalized patients...
June 2016: Frontiers of Medicine
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