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https://www.readbyqxmd.com/read/28426669/a-dynamic-genetic-hormonal-regulatory-network-model-explains-multiple-cellular-behaviors-of-the-root-apical-meristem-of-arabidopsis-thalian
#1
Mónica L García-Gómez, Eugenio Azpeitia, Elena R Álvarez-Buylla
The study of the concerted action of hormones and transcription factors is fundamental to understand cell differentiation and pattern formation during organ development. The root apical meristem of Arabidopsis thaliana is a useful model to address this. It has a stem cell niche near its tip conformed of a quiescent organizer and stem or initial cells around it, then a proliferation domain followed by a transition domain, where cells diminish division rate before transiting to the elongation zone; here, cells grow anisotropically prior to their final differentiation towards the plant base...
April 20, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28424382/-near-miss-outcomes-in-gambling-games
#2
Zsuzsa Pecsenye, Gyozo Kurucz
BACKGROUND: Games of chance operate with an intermittent reinforcement schedule in which the number of games takes the player to win differ in each turn thus they can not predict when the next positive reinforcement arrives. The near miss outcome (close to winning but actually a losing outcome) can be interpreted as a secondary (built in) reinforcement within variable ratio reinforcement schedule that presumably contribute to the development and maintanance of gambling addiction. METHODS: The aim of this publication would be to introduce near miss outcomes and to summarize and critically analyze literature connected to this issue...
2017: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/28421650/keeping-up-with-the-kids-diffusion-of-innovation-in-pediatric-emergency-medicine-among-emergency-physicians
#3
Robert L Cloutier, Rakesh D Mistry, Stephen Cico, Chris Merritt, Samuel H F Lam, Marc Auerbach, L Melissa Skaugset, Jean Klig, Meg Wolff, Myto Duong, Jennifer Walthall
With 30,000,000 emergency department (ED) visits annually, children account for nearly one fourth of all ED visits in the United States. Despite these statistics, EDs across the country remain underprepared to care for pediatric patients [1, 2]. Based on published data, only 45% of EDs report having a pediatric quality improvement plan in place, one third of hospitals do not weigh children in kilograms, less than half have disaster plans in place for pediatric patients and more than 15% are missing critical pediatric emergency equipment [1]...
April 19, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28421402/the-effect-of-losses-disguised-as-wins-and-near-misses-in-electronic-gaming-machines-a-systematic-review
#4
REVIEW
K R Barton, Y Yazdani, N Ayer, S Kalvapalle, S Brown, J Stapleton, D G Brown, K A Harrigan
Near misses and losses disguised as wins have been of interest to gambling researchers and policymakers for many years (e.g., Griffiths in J Gambl Stud 9(2):101-120, 1993). This systematic literature review describes the behavioural, psychological, and psychobiological effects of near misses and losses disguised as wins (LDWs) in an effort to evaluate their precise influence on the player and to highlight areas requiring further investigation. A systematic search for relevant studies was conducted using Scopus, PubMed, PsycINFO, ProQuest Sociology databases, and the Gambling Research Exchange Ontario Knowledge Repository...
April 18, 2017: Journal of Gambling Studies
https://www.readbyqxmd.com/read/28417202/cardiorespiratory-fitness-and-muscle-strength-in-pancreatic-cancer-patients
#5
Dorothea Clauss, Christine Tjaden, Thilo Hackert, Lutz Schneider, Cornelia M Ulrich, Joachim Wiskemann, Karen Steindorf
PURPOSE: Cancer patients frequently experience reduced physical fitness due to the disease itself as well as treatment-related side effects. However, studies on physical fitness in pancreatic cancer patients are missing. Therefore, we assessed cardiorespiratory fitness and muscle strength of pancreatic cancer patients. METHODS: We included 65 pancreatic cancer patients, mostly after surgical resection. Cardiorespiratory fitness was assessed using cardiopulmonary exercise testing (CPET) and 6-min walk test (6MWT)...
April 17, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28413825/color-change-detection-activity-in-the-primate-superior-colliculus
#6
James P Herman, Richard J Krauzlis
The primate superior colliculus (SC) is a midbrain structure that participates in the control of spatial attention. Previous studies examining the role of the SC in attention have mostly used luminance-based visual features (e.g., motion, contrast) as the stimuli and saccadic eye movements as the behavioral response, both of which are known to modulate the activity of SC neurons. To explore the limits of the SC's involvement in the control of spatial attention, we recorded SC neuronal activity during a task using color, a visual feature dimension not traditionally associated with the SC, and required monkeys to detect threshold-level changes in the saturation of a cued stimulus by releasing a joystick during maintained fixation...
March 2017: ENeuro
https://www.readbyqxmd.com/read/28411898/balancing-overscreening-and-underdiagnosis-in-secondary-hypertension-the-case-of-fibromuscular-dysplasia
#7
REVIEW
Marcel Ruzicka, Sarah E Kucharski, Swapnil Hiremath
Knowledge about fibromuscular dysplasia (FMD) has broadened over the last several decades. It is no longer considered a rare and benign entity limited to renal arteries and causing just hypertension. It affects other parts of the arterial tree nearly as frequently as the renal arteries. Complications of undiagnosed and untreated extrarenal FMD can be debilitating and life threatening. However, this disease, specifically extrarenal FMD, is not well known to many physicians and patients. Combined with the nonspecific symptoms and signs of the disease, this leads to delayed diagnosis and missed opportunity to prevent serious vascular complications...
May 2017: Cardiology Clinics
https://www.readbyqxmd.com/read/28406275/high-self-reported-non-adherence-to-antiretroviral-therapy-amongst-adolescents-living-with-hiv-in-malawi-barriers-and-associated-factors
#8
Maria H Kim, Alick C Mazenga, Xiaoying Yu, Saeed Ahmed, Mary E Paul, Peter N Kazembe, Elaine J Abrams
INTRODUCTION: Globally adolescents and young adults account for more than 40% of new HIV infections, and HIV-related deaths amongst adolescents increased by 50% from 2005 to 2012. Adherence to antiretroviral therapy (ART) is critical to control viral replication and preserve health; however, there is a paucity of research on adherence amongst the growing population of adolescents living with HIV/AIDS (ALHIV) in Southern Africa. We examined levels of self-reported ART adherence, barriers to adherence, and factors associated with non-adherence amongst ALHIV in Malawi...
March 30, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28405123/maternal-near-miss-a-perimortem-caesarean-section-resulting-in-a-remarkable-foetomaternal-recovery-in-a-rural-tertiary-care-centre-in-eastern-india
#9
Dasgupta Anirban, Ramotra Rohini, Santra Debjyoti, Dasgupta Subhendu, Pushpam Preeti, Mandal Sibapada, Murmu Shankar
No abstract text is available yet for this article.
April 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28404198/molecular-fluorescence-guided-surgery-of-peritoneal-carcinomatosis-of-colorectal-origin-a-single-centre-feasibility-study
#10
Niels J Harlaar, Marjory Koller, Steven J de Jongh, Barbara L van Leeuwen, Patrick H Hemmer, Schelto Kruijff, Robert J van Ginkel, Lukas B Been, Johannes S de Jong, Gursah Kats-Ugurlu, Matthijs D Linssen, Annelies Jorritsma-Smit, Marleen van Oosten, Wouter B Nagengast, Vasilis Ntziachristos, Gooitzen M van Dam
BACKGROUND: Optimum cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is essential for the curative treatment of peritoneal carcinomatosis of colorectal origin. At present, surgeons depend on visual inspection and palpation for tumour detection. Improved detection of tumour tissue using molecular fluorescence-guided surgery could not only help attain a complete cytoreduction of metastatic lesions, but might also prevent overtreatment by avoiding resection of benign lesions...
December 2016: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28400712/inverted-u-shaped-curvilinear-relationship-between-challenge-and-one-s-intrinsic-motivation-evidence-from-event-related-potentials
#11
Qingguo Ma, Guanxiong Pei, Liang Meng
The balance between task demand and one's competence is critical for the maintenance of intrinsic motivation. According to Flow theory and Self-determination theory, optimal challenge gives rise to the maximum intrinsic motivation, and an inverted U-shaped curvilinear relationship between perceived challenge and one's intrinsic motivation is suggested. In order to provide direct experimental evidences for predictions of these theories, in this study, we employed the two-player StopWatch game that we previously designed, which made references to the game format of a badminton tournament...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28399034/sentinel-lymphadenectomy-in-vulvar-cancer-using-near-infrared-fluorescence-from-indocyanine-green-compared-with-technetium-99m-nanocolloid
#12
Philipp Soergel, Hermann Hertel, Anna Kaarina Nacke, Rüdiger Klapdor, Thorsten Derlin, Peter Hillemanns
OBJECTIVE: Nowadays, sentinel diagnostic is performed using technetium 99m (Tc) nanocolloid as a radioactive marker and sometimes patent blue. In the last years, indocyanine green has been evaluated for sentinel diagnostic in different tumor entities. Indocyanine green is a fluorescent molecule that emits a light signal in the near-infrared band after excitation. Our study aimed to evaluate indocyanine green compared with the criterion-standard Tc-nanocolloid. METHODS: We included patients with primary, unifocal vulvar cancer of less than 4 cm with clinically node-negative groins in this prospective trial...
April 8, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28397797/general-characteristics-of-relative-dispersion-in-the-ocean
#13
Raffaele Corrado, Guglielmo Lacorata, Luigi Palatella, Rosalia Santoleri, Enrico Zambianchi
The multi-scale and nonlinear nature of the ocean dynamics dramatically affects the spreading of matter, like pollutants, marine litter, etc., of physical and chemical seawater properties, and the biological connectivity inside and among different basins. Based on the Finite-Scale Lyapunov Exponent analysis of the largest available near-surface Lagrangian data set from the Global Drifter Program, our results show that, despite the large variety of flow features, relative dispersion can ultimately be described by a few parameters common to all ocean sub-basins, at least in terms of order of magnitude...
April 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28394804/risk-factors-prevalence-and-site-concordance-of-human-papillomavirus-in-high-risk-greek-men
#14
Savas Tsikis, Lea Hoefer, George Bethimoutis, Electra Nicolaidou, Vassilios Paparizos, Christina Antoniou, Leonidas Chardalias, Georgios-Emmanouil Stavropoulos, Shruti Sharma, Bradley C Long, Ibro Mujacic, Sabah Kadri, Jeremy P Segal, Larissa V Furtado, John Schneider, Angella Charnot-Katsikas
The aim of this study was to determine the risk factors, genotype-specific prevalence, and concordance of human papillomavirus (HPV) infections at three anatomical sites in a cohort of high-risk Greek men. Patients were recruited from sexually transmitted infection and HIV clinics in Athens. Samples were obtained from oral, penile, and anal sites of 294 study participants and HPV testing was performed on 882 samples using next-generation sequencing. Patients also completed a questionnaire assessing risk factors for infection...
April 7, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28392728/external-quality-assessment-beyond-the-analytical-phase-an-australian-perspective
#15
REVIEW
Tony Badrick, Stephanie Gay, Euan J McCaughey, Andrew Georgiou
External Quality Assessment (EQA) is the verification, on a recurring basis, that laboratory results conform to expectations for the quality required for patient care. It is now widely recognised that both the pre- and post-laboratory phase of testing, termed the diagnostic phases, are a significant source of laboratory errors. These errors have a direct impact on both the effectiveness of the laboratory and patient safety. Despite this, Australian laboratories tend to be focussed on very narrow concepts of EQA, primarily surrounding test accuracy, with little in the way of EQA programs for the diagnostic phases...
February 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28392577/educating-orphaned-and-vulnerable-children-in-elgeyo-marakwet-county-kenya
#16
Grace Jepkemboi, Pauline Jolly, KaNesha Gillyard, Lydia Lissanu
According to UNICEF, 13.3 million children (0-17 years) worldwide have lost one or both parents to AIDS. Nearly 12 million of these children live in sub-Saharan Africa. Together, with other children who have been severely impacted by the AIDS pandemic, these orphaned and vulnerable children (OVC) are at higher risk of missing out on schooling, living in households with less food security, and suffering from anxiety and depression. Although the needs of OVC are complex and influenced by numerous variables, the provision of education has the potential to address many aspects of a child's well-being, including food and nutrition, health care, social welfare, and protection...
September 2016: Childhood Education
https://www.readbyqxmd.com/read/28391614/a-mixed-methods-study-of-maternal-near-miss-and-death-after-emergency-cesarean-delivery-at-a-referral-hospital-in-somaliland
#17
Hamda A Abdillahi, Khadra A Hassan, Jonah Kiruja, Fatumo Osman, Jama A Egal, Marie Klingberg-Allvin, Kerstin Erlandsson
OBJECTIVE: To explore maternal near miss and death after emergency cesarean delivery in Somaliland, including the impact of the prerequisite for family consent. METHODS: A facility-based, mixed-methods study was conducted to assess all maternal near misses and deaths recorded at a referral hospital that provided services to women from all regions of Somaliland. The data sources comprised a quantitative prospective cross-sectional study using the WHO near-miss tool (performed from August 1 to December 31, 2015) and qualitative interviews with 17 healthcare providers working at the referral hospital who were in direct contact with the women in labor (performed from January 15 to March 15, 2015)...
April 8, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28390547/image-acquisition-in-general-radiography-the-utilisation-of-ddr
#18
C M Hayre, A Eyden, S Blackman, K Carlton
OBJECTIVE: This article explores image acquisition with DDR. General radiographic technology continues to advance therefore it remains paramount to continually reflect on DDR hardware and software amongst radiographers in an imaging modality that constitutes approximately 90% of all radiological examinations. METHOD: This article reports findings from a wider ethnographic study of two general radiography environments in the United Kingdom (UK). Participant observation and semi-structured interviews were the methods used to uncover original data...
May 2017: Radiography
https://www.readbyqxmd.com/read/28389543/genetic-stability-and-evolution-of-sigb-allele-used-for-listeria-sensu-stricto-subtyping-and-phylogenetic-inference
#19
Jingqiu Liao, Martin Wiedmann, Jasna Kovac
Sequencing of single genes remains an important tool that allows for rapid classification of bacteria. Sequencing of a portion of sigB, which encodes a stress responsive alternative sigma factor, has emerged as a commonly used molecular tool for initial characterization of diverse Listeria isolates. In this study, evolutionary approaches were used to assess the validity of sigB allelic typing for Listeria For a dataset of 4,280 isolates, sigB allelic typing showed a Simson Index of Discrimination of 0.96. Analyses of 164 sigB allelic types (ATs) found among the 6 Listeria sensu stricto (s...
April 7, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28384490/multiuse-trail-intersection-safety-analysis-a-crowdsourced-data-perspective
#20
Ben Jestico, Trisalyn A Nelson, Jason Potter, Meghan Winters
Real and perceived concerns about cycling safety are a barrier to increased ridership in many cities. Many people prefer to bike on facilities separated from motor vehicles, such as multiuse trails. However, due to underreporting, cities lack data on bike collisions, especially along greenways and multiuse paths. We used a crowdsourced cycling incident dataset (2005-2016) from BikeMaps.org for the Capital Regional District (CRD), BC, Canada. Our goal was to identify design characteristics associated with unsafe intersections between multiuse trails and roads...
April 3, 2017: Accident; Analysis and Prevention
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