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emla ointment

M Ghasemi
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
Dilia Giuggioli, Andreina Manfredi, Caterina Vacchi, Marco Sebastiani, Amelia Spinella, Clodoveo Ferri
OBJECTIVES: Digital ulcers (DU) may develop in half of systemic sclerosis (SSc) patients; they are often resistant to treatments. Deep wound debridement is crucial for DU healing, but very difficult to carry out without adequate procedural pain management. Here, we report the results of our experience on procedural pain management in scleroderma DU. METHODS: The study included 51 DU observed in 32 consecutive SSc patients; procedural pain was treated following a definite schedule: local lidocaine and prilocaine (25 mg of either agent per gram of cream, EMLA 5%) were initially used in all cases, followed by local and oral morphine, according to the severity of pain scored on a 10 cm visual analogue scale (VAS)...
January 2015: Clinical and Experimental Rheumatology
Sediqeh Khalili, Mahboubeh Safavi, Rozita Rezaei, Maria Bidmeshki, Fatemeh Shirzad, Mostafa Nasiri
AIM: This study was aimed to explore the effect of applying diclofenac gel and a eutectic mixture of local anesthetic (EMLA) cream on vein puncture pain severity with vein catheter in the patients undergoing cesarean section. MATERIALS AND METHODS: The sample comprised 90 women undergoing elective cesarean section that referred to Imam Ali Hospital's maternity section in Amol city (Northern Iran). Data collection tools included visual analog scale for pain severity and a checklist for short term possible side-effects of diclofenac gel, EMLA cream and Vaseline ointment as placebo...
September 2014: International Journal of Applied and Basic Medical Research
John M David, Sandra Duarte Vogel, Kimberly Longo, Daniel Sanchez, Gregory Lawson
OBJECTIVE: To investigate a topical local anesthesia technique as a means to prevent and/or diminish pain in mice in a laboratory setting associated with tail vein injections performed by personnel in training. STUDY DESIGN: Prospective, randomized experimental trial. ANIMALS: Thirty six adult female, 23-28 g CD-1 mice from an in-house training colony. They were acclimated to routine training and handling classes. METHODS: Eutectic mixture of local anesthetics (EMLA) cream (2...
November 2014: Veterinary Anaesthesia and Analgesia
Michelle Franz-Montan, Daniela Baroni, Giovana Brunetto, Viviane Roberta Vieira Sobral, Camila Morais Gonçalves da Silva, Paulo Venâncio, Patricia Wiziack Zago, Cintia Maria Saia Cereda, Maria Cristina Volpato, Daniele Ribeiro de Araújo, Eneida de Paula, Francisco Carlos Groppo
OBJECTIVE: To characterize liposomal-lidocaine formulations for topical use on oral mucosa and to compare their in vitro permeation and in vivo anesthetic efficacy with commercially available lidocaine formulations. MATERIALS AND METHODS: Large unilamellar liposomes (400 nm) containing lidocaine were prepared using phosphatidylcholine, cholesterol, and α-tocoferol (4:3:0.07, w:w:w) and were characterized in terms of membrane/water partition coefficient, encapsulation efficiency, size, polydispersity, zeta potential, and in vitro release...
March 2015: Journal of Liposome Research
Reem Al Qahtani, Laila Younis Abu-Salem, Kamalesh Pal
BACKGROUND: Neonatal circumcision is one of the oldest and most frequently performed surgical procedures on males. Newborns demonstrate strong endogenous reaction to pain and therefore modalities are being explored for optimum pain relief during circumcision. Pediatric nurses have a vital role for the use of these modalities and minimising the pain response during the neonatal minor procedures. AIM: The aim of this study was to assess the effectiveness of eutectic mixture of local anaesthetic (EMLA) cream compared with oral sucrose and both in alleviating pain in neonatal circumcision...
January 2014: African Journal of Paediatric Surgery: AJPS
Salvatore Martellucci, Giulio Pagliuca, Marco de Vincentiis, Antonio Greco, Massimo Fusconi, Armando De Virgilio, Chiara Rosato, Andrea Gallo
Radiofrequency volumetric tissue reduction is a minimally invasive technique in the treatment of turbinate hypertrophy and is generally performed under local anesthesia. However, perioperative discomfort and pain are common side effects and studies concerning the technique of choice to anesthetize the nasal mucosa in this procedure are lacking. The aim of this prospective controlled trial is to assess the effectiveness of EMLA(®) cream as a topical anesthetic for radiofrequency volumetric tissue reduction of inferior turbinates comparing its effect with that obtained using a traditional anesthetic technique...
October 2014: European Archives of Oto-rhino-laryngology
Manal Abuelkheir, Deema Alsourani, Ayman Al-Eyadhy, Mohamad-Hani Temsah, Sultan Ayoub Meo, Fahad Alzamil
OBJECTIVES: To evaluate the effectiveness of topical eutectic mixture of local anaesthetics (EMLA®) cream in reducing the pain associated with vaccination injections. METHODS: This was a randomized, double-blind, placebo-controlled study that included children who presented for routine immunization. Eligible children were randomly assigned to receive either EMLA® or placebo cream. The Modified Behavioural Pain Scale (MBPS) was used to assess baseline and postvaccination pain scores, while a visual analogue scale (VAS) was used to assess pain at the time of the needle prick and at the end of the injection...
April 2014: Journal of International Medical Research
Erich Knolle, Markus Zadrazil, Gabor Geza Kovacs, Stephanie Medwed, Gisela Scharbert, Michael Schemper
Topical capsaicin 8% was developed for the treatment of peripheral neuropathic pain. The pain reduction is associated with a reversible reduction of epidermal nerve fiber density (ENFD). During its application, topical capsaicin 8% provokes distinct pain. In a randomized, double-blind study analyzed with a block factorial analysis of variance, we tested whether cooling the skin would result in reliable prevention of the application pain without inhibiting reduction of ENFD. A capsaicin 8% patch was cut into 4 quarters and 2 each were applied for 1 hour on the anterior thighs of 12 healthy volunteers...
December 2013: Pain
Baldomero Arnau, Esther Jovell, Stephanie Redón, Marta Canals, Vanessa Mir, Elena Jiménez
We investigated the efficacy of 5% lidocaine 25 mg-prilocaine 25 mg/g cream (EMLA(®) ) applied to the uterine cervix for reducing pain during diagnostic or operative hysteroscopy, using a visual analogue scale (VAS) for pain in a prospective randomized, non-blinded, controlled study in 92 successive patients. Patients were randomized to either 3 mL of EMLA cream or 3 mL of ultrasound gel (placebo), placed endocervically and exocervically, 10 min before hysteroscopy. Intensity of pain was evaluated immediately after the procedure using a 10-cm VAS...
August 2013: Acta Obstetricia et Gynecologica Scandinavica
Devendra Gupta, Kamal Kishore, Sonal Rastogi, Prabhat K Singh, Anil Agarwal, Uttam Singh
BACKGROUND: Topical capsaicin and eutectic mixture of local anesthetics (EMLA) have been found to be equally effective in minimizing the pain of venipuncture. After the injection of capsaicin, both tertiary amine local anesthetics and their quaternary ammonium derivatives can elicit a prolonged and predominantly sensory/nociceptor selective block. We hypothesized that the combined application of capsaicin and ELMA will be more effective than their individual effect, and lower concentrations of individual drugs in this mixture may also be associated with reduced side effects...
March 2013: Anesthesia and Analgesia
Michelle Briggs, E Andrea Nelson, Marrissa Martyn-St James
BACKGROUND: Venous leg ulcers affect up to 1% of people at some time in their lives and are often painful. The main treatments are compression bandages and dressings. Topical treatments to reduce pain during and between dressing changes are sometimes used. OBJECTIVES: To determine the effects of topical agents or dressings for pain in venous leg ulcers. SEARCH METHODS: For this third update the following databases were searched: Cochrane Wounds Group Specialised Register (searched 9 May 2012); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 4); Ovid MEDLINE (2009 to April Week 4 2012); Ovid MEDLINE (In-Process & Other Non-Indexed Citations May 08, 2012); Ovid EMBASE (2009 to 2012 Week 18); and EBSCO CINAHL (2009 to May 2 2012)...
November 14, 2012: Cochrane Database of Systematic Reviews
S Schreiber, L Ronfani, G P Chiaffoni, L Matarazzo, M Minute, E Panontin, F Poropat, C Germani, E Barbi
UNLABELLED: Venipuncture and intravenous cannulation are the most common painful procedures performed on children. The most widely used topical anesthetic is eutectic mixture of local anesthetics (EMLA). EMLA use is associated with a transient cutaneous vasoconstriction which can make it difficult to identify veins. We assessed with a prospective, multicenter, observational study whether EMLA interferes with venipuncture and intravenous cannulation. The primary study outcome was a success at first attempt in the course of venipuncture or venous cannulation...
February 2013: European Journal of Pediatrics
Stephanie C J Keating, Aurelie A Thomas, Paul A Flecknell, Matthew C Leach
BACKGROUND: Ear tattooing is a routine procedure performed on laboratory, commercial and companion rabbits for the purpose of identification. Although this procedure is potentially painful, it is usually performed without the provision of analgesia, so compromising animal welfare. Furthermore, current means to assess pain in rabbits are poor and more reliable methods are required. The objectives of this study were to assess the physiological and behavioural effects of ear tattooing on rabbits, evaluate the analgesic efficacy of topical local anaesthetic cream application prior to this procedure, and to develop a scale to assess pain in rabbits based on changes in facial expression...
2012: PloS One
Fan Hui-Chen, Chen Hsiu-Lin, Chen Shun-Line, Tasi Tai-Ling, Wang Li-Jung, Tseng Hsing-I, Yang San-Nan
BACKGROUND: Painful procedures for premature infants in neonatal intensive care units remain inevitable. The goal of this study is to evaluate the effect of an eutectic mixture of local anesthetic (EMLA) cream for minimizing pain in premature infants during venipuncture in neonatal intensive care units. METHODS: This study enrolled 32 premature infants. A repeated-measures design was used. The scores of the 'Neonatal Pain, Agitation and Sedation Scale' (N-PASS) of each enrolled preterm infant were measured before, during and 10 min after venipuncture without and with EMLA cream use...
February 2013: Journal of Tropical Pediatrics
Mojgan Rahimi, Ali Reza Kazemeini, Nasim Pourtabatabaei, Amir Reza Honarmand
PURPOSE: We compared the efficacy and side effects of diclofenac and a topical eutectic mixture of local anesthetics (EMLA) for pain relief after hemorrhoidectomy. METHODS: Ninety patients, nominated for elective hemorrhoidectomy, were recruited for this randomized clinical trial and were randomly categorized into three groups (30 patients in each group). After surgery, the patients in the first group received one 100 mg diclofenac suppository, those in the second group received 5 g of EMLA, and those in the third group received 5 g of petrolatum ointment (control group)...
December 2012: Surgery Today
J-L Schmutz, P Trechot
No abstract text is available yet for this article.
January 2012: Annales de Dermatologie et de Vénéréologie
Lori Huff, Annette Hamlin, Diane Wolski, Tracy McClure, Aris Beoglos Eliades, Laurie Weaver, Deb Shelestak
The purpose of this study was to investigate whether the application of heat placed to a child's potential intravenous (IV) site after the application of EMLA Cream™ decreases vasoconstriction, therefore promoting atraumatic care in the hospitalized pediatric patient. Venipuncture in children is a painful and frequently performed procedure. While use of EMLA Cream™ to reduce pain on insertion is a common practice with pediatric patients, no studies had measured venous size in relation to EMLA Cream™ and heat application...
2009: Issues in Comprehensive Pediatric Nursing
T Iannitti, S Capone, B Palmieri
AIM: Nowadays there is great attention in trying to slow and reverse the facial aging process. Esthetic medicine has been primarily based on the surgical approach for many years, but now, in order to solve the problem of aging skin, there is an increasing interest into non-invasive, possibly painless, procedures that can guarantee the patient a quick recovery. In this perspective the use of chemical peeling and dermabrasion, to achieve skin rejuvenation, is growing worldwide. These techniques are also relevant to treat skin pigmentation irregularities and to remove keratoses, lentigines, acne and other skin related conditions...
June 2011: Minerva Chirurgica
Santosh Kumar, Sunil Kumar, Raguram Ganesamoni, Arup K Mandal, Seema Prasad, Shrawan K Singh
The objective of the study was to compare the efficacy of dimethyl sulfoxide (DMSO) mixed with lignocaine and eutectic mixture of local anesthetics (EMLA) cream as topically applied surface anesthetics in relieving pain during shock wave lithotripsy (SWL) in a prospective randomized study. Of the 160 patients, 80 patients received DMSO with lignocaine and 80 patients received EMLA cream, applied to the skin of the flank at the area of entry of shock waves. SWL was done with Seimens lithostar multiline lithotripter...
June 2011: Urological Research
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