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Cesare Carlo Ferrari, Kerstin Lorenz, Gianlorenzo Dionigi, Henning Dralle
BACKGROUND: Thyroid hemiagenesis is a rare congenital anomaly, and still more rarely associated with primary hyperparathyroidism (pHPT). Due to the embryologic pathways of the thyroid and parathyroid glands, it remains unclear whether or not thyroid hemiagenesis may be linked to ipsilateral parathyroid agenesis, and consequently, surgical strategy for thyroid hemiagenesis associated pHPT (THAP) does not only depend on preoperative localization but also on the thyroid anomaly. METHODS: Including the present case report, a total of nine cases with THAP retrieved from the literature were reviewed...
December 2014: Langenbeck's Archives of Surgery
G Fröhlich, A Grawe, N Schmidt, R Roth, E Märker-Hermann
HISTORY AND ADMISSION FINDINGS: A 37-year-old man complained about a lack of strength, an unproductive cough and myalgia predominantly thigh-focused with subfebrile temperatures for days. INVESTIGATIONS: Laboratory investigations indicated rhabdomyolysis with acute kidney injury (AKI). Drug misuse was denied. Exertion and trauma could be excluded as well as rheumatologic or other infectious causes often responsible for rhabdomyolysis. PCR of a nasopharyngeal swab was positive for influenza A virus subtype H1N1...
November 2013: Deutsche Medizinische Wochenschrift
B Walther
BACKGROUND: Vitamin K antagonists not only influence the synthesis of coagulation factors but also the activation of other vitamin K dependent proteins. Among other possible side effects, arterial calcification has been focused on in recent years. HISTORY AND FINDINGS: Four patients under long-term anticoagulation for more than 10 years developed medial calcific sclerosis. In case 1 we identified an unexplained medial calcific sclerosis on x-ray after a trauma by chance...
May 2013: Deutsche Medizinische Wochenschrift
M Haap, O Tschritter, F Artunc, I Rettig, R Riessen
A hypercalcemic crisis is a life-threatening disease with multiorgan failure due to severe hypercalcemia. If left untreated, a hypercalcemic crisis is associated with a very high mortality and requires immediate diagnostic and therapeutic interventions. Especially a rapid rise to high calcium levels impairs the function of several organ systems and leads to central nervous, renal, cardiovascular and gastrointestinal symptoms. A hypercalcemic crisis is caused in more than 90 % by malignancy or primary hyperparathyreoidism and only in very rare cases by other diseases such as granulomatous diseases or other endocrinological diseases...
May 2012: Deutsche Medizinische Wochenschrift
C Ibbeken, J U Becker, M W Baumgärtel
Lithium is widely used in the treatment of bipolar disorders. Long-term administration of lithium often leads to side effects concerning the subjects: nephrology, endocrinology and surgery. This review emphasizes nephrotoxicity.Lithium treatment may disturb responsiveness to antidiuretic hormone (ADH), causing a nephrogenic diabetes insipidus. Furthermore long-term lithium therapy may trigger hyperparathyreoidism with hypercalcemia and chronic interstitial nephritis with development of microcysts. Long-term patients have an increased risk to develop impaired renal function...
January 2012: Deutsche Medizinische Wochenschrift
A Sauer-Schulz, G Schnauder, H Dittmann, K Müssig
HISTORY AND ADMISSION FINDINGS: A 51-year-old woman was admitted from a mental institution for evaluation of hypercalcemia. She was treated with lithium for a bipolar disorder since 25 years. She complained of polydypsia and polyuria. The physical examination findings were unremarkable up to manic symptoms. INVESTIGATIONS: Laboratory values showed elevated serum calcium and parathormone. Serum phosporus was within the normal range. Neck ultrasound revealed a goiter with one nodule in the right thyroid lobe and a suspected enlarged lower left parathyroid gland...
December 2011: Deutsche Medizinische Wochenschrift
Z Somlóová, J Rosa, O Petrák, B Strauch, T Zelinka, R Holaj, J Widimský
Arterial hypertension is a common worldwide disease with a prevalence of approximately 26%. Secondary cause is known in 5-10% of patients with hypertension. We should think of secondary hypertension in all patients with resistant hypertension, in patients with sudden deterioration in the control of hypertension and in patients with laboratory and clinical signs of diseases associated with secondary hypertension. It is important to distinguish between secondary hypertension and pseudo-resistance (noncompliance to treatment, white coat syndrome)...
September 2011: Vnitr̆ní Lékar̆ství
T Kienitz, M Ventz, E Kaminsky, M Quinkler
INTRODUCTION: The most common form of familial hypophosphatemic rickets is X-linked. PHEX has been identified as the gene defective in this phosphate wasting disorder leading to decreased renal phosphate reabsorption, hypophosphatemia and inappropriate concentrations of 1,25-dihydroxyvitamin D in regard to hypophosphatemia. Clinical manifestation are skeletal deformities, short stature, osteomalacia, dental abscesses, bone pain, and loss of hearing. SUBJECTS AND METHODS: We report 3 cases of hypophosphatemic rickets with genetic mutational analysis of the PHEX gene...
July 2011: Experimental and Clinical Endocrinology & Diabetes
G Türkoglu-Raach, H-J Gröne, T Sitter, M Fischereder
HISTORY AND CLINICAL FINDINGS: A 70-year-old woman was admitted to hospital with fatigue, pallor and shortness of breath on mild exertion. In her past medical history only borderline hypertension and allergy to penicillin were to note. INVESTIGATIONS: Actual laboratory findings revealed renal failure with metabolic acidosis and hyperkalaemia. A normochrome normocytic anemia and secondary hyperparathyreoidism were suggestive of a subacute course. The renal biopsy showed histological features of a subacute tubulo-interstitial nephritis...
June 2010: Deutsche Medizinische Wochenschrift
N Diehm, J C van den Berg, V Schnyder, J Bühler, T Willenberg, M Widmer, M G Mohaupt, I Baumgartner
BACKGROUND: Vascular access patency is of vital importance for patients requiring haemodialysis. This analysis validates potential risk factors and benefits in patients undergoing vascular access procedures. PATIENTS AND METHODS: Vascular access procedures performed over a two-year period were retrospectively analysed. Clinical data and concomitant medication were retrieved from files as were surgical data following a standardized data capture sheet. Outcome parameters were primary (PP) and secondary patency (SP) as well as freedom from repeated revascularization...
May 2010: VASA. Zeitschrift Für Gefässkrankheiten
No abstract text is available yet for this article.
April 19, 1947: Medical Journal of Australia
Luis Augusto Tavares Russo, Luiz Henrique de Gregório, Paulo Gustavo Sampaio Lacativa, Lizanka Paola F Marinheiro
OBJECTIVES: This study was designed to determine mean serum concentrations of 25-hydroxyvitamin D (25OHD) in postmenopausal women with low bone mineral density (BMD), to find the cutoff of parathormone (PTH) elevation, and to evaluate the correlation 25OHD with BMD, biochemical parameters and vertebral fracture presence. METHODS: Transversal study, with collection of 25OHD and PTH, and determination of DMO and column radiograph. RESULTS: A high incidence of inadequate serum concentrations of 25OHD (68...
December 2009: Arquivos Brasileiros de Endocrinologia e Metabologia
Dariusz Runowski, Bozena Jachimiak
UNLABELLED: The medical history and treatment of 2.5 years old girl with chronic kidney disease and heavy hyperparathyreoidism was presented in this case report. This girl was treated by peritoneal dialysis (APD) due to chronic kidney disease and congenital nephrotic syndrome. The secondary paraidothyreoidism was a reason of the epiphysial of the upper end of the femur, which appeared despite of the treatment by the Vitamin D3 (Calciphediol and Alphacalcidol) and phosphate binding drugs like Calcium Carbonate and Sevelamer...
April 2009: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
P N Khalil, K Hallfeldt
No abstract text is available yet for this article.
November 6, 2008: MMW Fortschritte der Medizin
J Hedvig, L Podracká, D Potoceková
BACKGROUND: Cardiovascular diseases are the leading course of morbidity/mortality in children with chronic kidney disease. Recently it has been shown that a brain natriuretic peptide is a sensitive cardiac marker for classification of the cardiovascular risk in adults. Whether it has the same diagnostic value in children with chronic kidney diseases has to be established. The purpose of the study was to evaluate whether the brain natriuretic peptide can predict cardiac dysfunction in children with chronic kidney disease...
2008: Casopís Lékar̆ů C̆eských
St Farese
The Hungry Bone Syndrome (HBS) represents an important cause of prolonged hypocalcemia after parathyreoidectomy (PTX) due to primary, secondary or tertiary hyperparathyreoidism. The sudden postoperative withdrawal of parathyroid hormone (PTH) induces a stop in osteoclastic bone resorption without affecting the osteoblastic activity. Consequently, an increased bone uptake of calcium, phosphate and magnesium is observed. Risk factors for the development of HBS include: Large parathyroid adenomas, age > 60 years, high preoperative levels of serum PTH, calcium and alkaline phosphatase...
May 2007: Therapeutische Umschau. Revue Thérapeutique
Eli Johanne Nordal, Ingrid Os
BACKGROUND: Itching commonly occurs in patients with chronic renal failure, and can be a most distressful and sometimes disabling symptom. METHOD: This article is based on literature identified through a Pubmed search, textbooks and own clinical experience. RESULTS AND INTERPRETATION: Inflammatory processes seem to be important in the pathogenesis of uremic pruritus; mechanisms for interference from others factors are not fully understood...
May 3, 2007: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
Petar Kes, Nikolina Basić-Jukić, Ivana Jurić, Bruna Brunetta
Up to 90% of chronic haemodialysis patients have blood preasure (BP) greater than 140/90 mmHg. This suggests that only a minor number of the haemodialysis patients have adequate BP control. This is associated with significantly increased morbidity and mortality in haemodialysis population when compared with normal, healthy population. The main aim of antihypertensive treatment in hypertensive haemodialysis patients is to achieve BP values which should not differ from those recommended for general population...
November 2006: Lijec̆nic̆ki Vjesnik
S Adámek, P Libánský, O Nanka, J Sedý, P Pafko
453 patients underwent surgery for primary hyperparathyreoidism between 1994 and 2003. In all patients, biochemical parameters were monitored and X-ray with USG of the neck was done. Struma nodosa was concommitantly present in 48 % of treated patients with primary hyperparathyroidism. In such cases, MRI offers better resolution of soft tissues. 98.6 % of treated patients had postoperative decrease of blood calcium to normal level. 5.4 % of cases were reoperations for primary hyperparathyroidism. In 12 % of cases, pathologically changed parathyroid glands in dystopic localization were found...
April 2005: Zentralblatt Für Chirurgie
B Gerber, B Hauser, C E Reusch
1,25-Dihydroxycholecalciferol (1,25-(OH)2-D3) and 25-hydroxycholecalciferol (25-OH-D3) were measured among dogs with hypercalcaemia (total serum calcium > 3.01 mmol/L) due to various causes. All values were compared to those of healthy control dogs. Serum 1,25-(OH)]2-D3 was measured by a radioimmunoassay test and serum 25-OH-D3 was measured by a protein binding assay. 1,25-(OH)2-D3 ranged from 26 to 332 pmol/L (median 110.0) in dogs with lymphoma (n = 12); from 61 to 398 pmol/L (median 248.0) in dogs with primary hyperparathyreoidism (n = 5); from 28 to 310 pmol/L (median 88...
November 2004: Veterinary Research Communications
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