Ana Filipa Ferreira, Maria João Azevedo, Juliana Morais, Fábio Trindade, Francisca Saraiva, Sílvia Oliveira Diaz, Inês Nuno Alves, Mariana Fragão-Marques, Carla Sousa, Ana Paula Machado, Adelino Leite-Moreira, Benedita Sampaio-Maia, Carla Ramalho, António Sousa Barros, Inês Falcão-Marques
Pregnant women with cardiovascular risk (CVR) factors are highly prone to develop cardiovascular disease later in life. Thus, recent guidelines suggest extending the follow-up period to 1 yr after delivery. We aimed to evaluate cardiovascular remodeling during pregnancy and determine which CVR factors and potential biomarkers predict postpartum cardiac and vascular reverse remodeling (RR). Our study included a prospective cohort of 76 healthy and 54 obese and/or hypertensive and/or with gestational diabetes pregnant women who underwent transthoracic echocardiography, pulse-wave velocity (PWV), and blood collection at the 1st trimester (1T) and 3rd trimester (3T) of pregnancy as well as at the 1st/6th/12th mo after delivery...
October 1, 2023: American Journal of Physiology. Heart and Circulatory Physiology