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R Miller, K Schmidt, C Kirschbaum, S Enge
The internet-based assessment of response time (RT) and error rate (ERR) has recently become a well-validated alternative to traditional laboratory-based assessment, because methodological research has provided evidence for negligible setting- and setup-related differences in RT and ERR measures of central tendency. However, corresponding data on potential differences in the variability of such performance measures are still lacking, to date. Hence, the aim of this study was to conduct internet-based mental chronometry in both poorly standardized domestic and highly standardized laboratory environments and to compare the variabilities of the corresponding performance measures...
March 15, 2018: Behavior Research Methods
Umut Arslan, Emin Özmert, Sibel Demirel, Firdevs Örnek, Figen Şermet
PURPOSE: One of the main reasons for apoptosis and dormant cell phases in degenerative retinal diseases such as retinitis pigmentosa (RP) is growth factor withdrawal in the cellular microenvironment. Growth factors and neurotrophins can significantly slow down retinal degeneration and cell death in animal models. One possible source of autologous growth factors is platelet-rich plasma. The purpose of this study was to determine if subtenon injections of autologous platelet-rich plasma (aPRP) can have beneficial effects on visual function in RP patients by reactivating dormant photoreceptors...
March 15, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Tanya Moutray, Jennifer R Evans, Noemi Lois, David J Armstrong, Tunde Peto, Augusto Azuara-Blanco
BACKGROUND: Diabetic retinopathy (DR) is a chronic progressive disease of the retinal microvasculature associated with prolonged hyperglycaemia. Proliferative DR (PDR) is a sight-threatening complication of DR and is characterised by the development of abnormal new vessels in the retina, optic nerve head or anterior segment of the eye. Argon laser photocoagulation has been the gold standard for the treatment of PDR for many years, using regimens evaluated by the Early Treatment of Diabetic Retinopathy Study (ETDRS)...
March 15, 2018: Cochrane Database of Systematic Reviews
Sarah P Carter, Laura J Osborne, Keith D Renshaw, Elizabeth S Allen, Benjamin A Loew, Howard J Markman, Scott M Stanley
Long-distance communication has been frequently identified as essential to military couples trying to maintain their relationship during a deployment. Little quantitative research, however, has assessed the types of topics discussed during such communication and how those topics relate to overall relationship satisfaction. The current study draws on a sample of 56 Army couples who provided data through online surveys while the service member was actively deployed. These couples provided information on current marital satisfaction, topics discussed during deployment (problem talk, friendship talk, love talk), and how they communicated via synchronous media (e...
February 2018: Journal of Family Psychology: JFP
Matthew Buican, Zoltan Laczko
In various dimensions, we can sometimes compute observables of interacting conformal field theories (CFTs) that are connected to free theories via the renormalization group (RG) flow by computing protected quantities in the free theories. On the other hand, in two dimensions, it is often possible to algebraically construct observables of interacting CFTs using free fields without the need to explicitly construct an underlying RG flow. In this Letter, we begin to extend this idea to higher dimensions by showing that one can compute certain observables of an infinite set of unitary strongly interacting four-dimensional N=2 superconformal field theories (SCFTs) by performing simple calculations involving sets of nonunitary free four-dimensional hypermultiplets...
February 23, 2018: Physical Review Letters
Rugang Geng, Ram C Subedi, Hoang M Luong, Minh T Pham, Weichuan Huang, Xiaoguang Li, Kunlun Hong, Ming Shao, Kai Xiao, Lawrence A Hornak, Tho D Nguyen
Hyperfine interaction (HFI), originating from the coupling between spins of charge carriers and nuclei, has been demonstrated to strongly influence the spin dynamics of localized charges in organic semiconductors. Nevertheless, the role of charge localization on the HFI strength in organic thin films has not yet been experimentally investigated. In this study, the statistical relation hypothesis that the effective HFI of holes in regioregular poly(3-hexylthiophene) (P3HT) is proportional to 1/N^{0.5} has been examined, where N is the number of the random nuclear spins within the envelope of the hole wave function...
February 23, 2018: Physical Review Letters
P Rodriguez-Fernandez, A E White, N T Howard, B A Grierson, G M Staebler, J E Rice, X Yuan, N M Cao, A J Creely, M J Greenwald, A E Hubbard, J W Hughes, J H Irby, F Sciortino
A long-standing enigma in plasma transport has been resolved by modeling of cold-pulse experiments conducted on the Alcator C-Mod tokamak. Controlled edge cooling of fusion plasmas triggers core electron heating on time scales faster than an energy confinement time, which has long been interpreted as strong evidence of nonlocal transport. This Letter shows that the steady-state profiles, the cold-pulse rise time, and disappearance at higher density as measured in these experiments are successfully captured by a recent local quasilinear turbulent transport model, demonstrating that the existence of nonlocal transport phenomena is not necessary for explaining the behavior and time scales of cold-pulse experiments in tokamak plasmas...
February 16, 2018: Physical Review Letters
Z H Zhong, R X Tang, M Zhou, X H Deng, Y Pang, W R Paterson, B L Giles, J L Burch, R B Tobert, R E Ergun, Y V Khotyaintsev, P-A Lindquist
Secondary flux ropes are suggested to play important roles in energy dissipation and particle acceleration during magnetic reconnection. However, their generation mechanism is not fully understood. In this Letter, we present the first direct evidence that a secondary flux rope was generated due to the evolution of an electron vortex, which was driven by the electron Kelvin-Helmholtz instability in an ion diffusion region as observed by the Magnetospheric Multiscale mission. The subion scale (less than the ion inertial length) flux rope was embedded within the electron vortex, which contained a secondary electron diffusion region at the trailing edge of the flux rope...
February 16, 2018: Physical Review Letters
Lauren Massimo, Sharon X Xie, Lior Rennert, Donna M Fick, Amy Halpin, Katerina Placek, Andrew Williams, Katya Rascovsky, David J Irwin, Murray Grossman, Corey T McMillan
To evaluate whether occupational attainment influences the trajectory of longitudinal cognitive decline in behavioral variant frontotemporal degeneration (bvFTD). Single-center, retrospective, longitudinal study. Sixty-three patients meeting consensus criteria for bvFTD underwent evaluation at the University of Pennsylvania Frontotemporal Degeneration Center. All patients were studied longitudinally on letter-guided fluency, category-naming fluency and Boston Naming Test (BNT). Occupational attainment was defined categorically by assigning each individual's occupation to a professional or non-professional category...
March 14, 2018: Brain Imaging and Behavior
Eva Purkey, Rupa Patel, Tracey Beckett, Françoise Mathieu
OBJECTIVE: To understand the primary care experiences of women who have a history of childhood trauma and chronic disease. DESIGN: Qualitative study using in-depth interviews with directed content analysis. SETTING: Family health team in Kingston, Ont. PARTICIPANTS: Twenty-six women. METHODS: Letters of invitation were sent to eligible participants followed by a telephone survey. Women with an adverse childhood experience (ACE) score of 4 or higher and with 2 or more chronic conditions were invited to participate in a one-on-one interview...
March 2018: Canadian Family Physician Médecin de Famille Canadien
Lunia Sofia Lima Azevedo, Lucas Gaspar Ribeiro, André Schmidt, Antônio Pazin Filho
We sought to evaluate the impact of Advanced Cardiac Life Support (ACLS) training in the professional career and work environment of physicians who took the course in a single center certified by the American Heart Association (AHA). Of the 4631 students (since 1999 to 2009), 2776 were located, 657 letters were returned, with 388 excluded from the analysis for being returned lacking addressees. The final study population was composed of 269 participants allocated in 3 groups (< 3 years, 3-5 and > 5years)...
March 2018: Ciência & Saúde Coletiva
Jeroen J Stekelenburg, Mirjam Keetels, Jean Vroomen
Numerous studies have demonstrated that the vision of lip movements can alter the perception of auditory speech syllables (McGurk effect). While there is ample evidence for integration of text and auditory speech, there are only a few studies on the orthographic equivalent of the McGurk effect. Here, we examined whether written text, like visual speech, can induce an illusory change in the perception of speech sounds on both the behavioral and neural level. In a sound categorization task, we found that both text and visual speech changed the identity of speech sounds from an /aba/-/ada/ continuum, but the size of this audiovisual effect was considerably smaller for text than visual speech...
March 14, 2018: European Journal of Neuroscience
Tianlu Wang, Celine R Gillebert
Visuospatial attention and short-term memory allow us to prioritize, select, and briefly maintain part of the visual information that reaches our senses. These cognitive abilities are quantitatively accounted for by Bundesen's theory of visual attention (TVA; Bundesen, 1990). Previous studies have suggested that TVA-based assessments are sensitive to inter-individual differences in spatial bias, visual short-term memory capacity, top-down control, and processing speed in healthy volunteers as well as in patients with various neurological and psychiatric conditions...
2018: Frontiers in Psychology
Jacqueline Cummine, Daniel Aalto, Amberley Ostevik, Kulpreet Cheema, William Hodgetts
Reading is a complex process that includes the integration of information about letters (graphemes) and sounds (phonemes). In many circumstances, such as noisy environments, response inhibition is an additional factor that plays a marked role in successful oral reading. Response inhibition can take the form of task relevant inhibition (i.e., foils in a go/no-go task) and task irrelevant inhibition (i.e., distractor information). Here we investigated task relevant inhibition by having participants (N = 30) take part in two tasks: go/no-go naming with nonwords foils (GNG-NW) and go/no-go naming with pseudohomophones foils (GNG-PH)...
March 12, 2018: Journal of Psycholinguistic Research
Ian M MacDonald, Pamela C Sieving
PURPOSE: To review the contributions to ophthalmic genetics through the American Journal of OphthalmologyDesign: Perspective. METHODS: A literature search to retrieve original articles, letters, editorials, and published lectures from 1966 to 2017, providing a 50 year review. Titles were excluded that gave no reference to genetics or presented findings related to a non-genetic ocular condition. RESULTS: From a search of the Scopus database, 719 articles were ascertained...
March 9, 2018: American Journal of Ophthalmology
Katharine Wallis, Rebecca Tuckey
INTRODUCTION High-risk prescribing in general practice is common and places patients at increased risk of adverse events. AIM The Safer Prescribing and Care for the Elderly (SPACE) intervention, comprising audit and feedback plus practice mail-out to patients with high-risk prescribing, was designed to promote medicines review and support safer prescribing. This study aims to test the SPACE intervention feasibility in general practice. METHODS This feasibility study involved an Auckland Primary Health Organisation (PHO), a clinical advisory pharmacist, two purposively sampled urban general practices, and seven GPs...
June 2017: Journal of Primary Health Care
Jeong-Im Han, Sujin Oh
This study examined two possible sources of asymmetrical lexical access: phonetic proximity to the nearest L1 category and orthographic information. Three groups of native Korean speakers learned Arabic non-words with sound pairs with/without an L1-dominant category (/l-r/ vs. /χ-ħ/), and then their phonetic categorization and lexical encoding abilities were evaluated. One group was presented with the same letters for the target pair (e.g., <l> for both /l/ and /r/), the second group, different letters (e...
March 12, 2018: Journal of Psycholinguistic Research
Clara Casco, Michele Barollo, Giulio Contemori, Luca Battaglini
BACKGROUND: In recent years, the introduction of visual rehabilitation for patients with homonymous visual field defects has been met with both enthusiasm and caution. Despite the evidence that restitutive training results in expansion of the visual field, several concerns have been raised. OBJECTIVE: We tested the effectiveness of a new rehabilitative protocol called "Neuro Restoration Training" (NRT) in reducing visual field defects and in restituting visual functions in the restored hemianopic area...
2018: Restorative Neurology and Neuroscience
Hee Sun Kang, Jennie C De Gagne, Ye Dong Son, Sun-Mi Chae
PROBLEM: It has been reported that some adolescents and young women who started taking human papillomavirus (HPV) vaccination are not completing all three doses. The aim of this study was to systematically review intervention studies on HPV vaccination completion. ELIGIBILITY CRITERIA: Intervention studies with a comparison group that assessed HPV vaccination completion rate as the primary outcome variable in adolescents and adults younger than 26years of age, and published in English from 2006 to 2016, were eligible for review...
March 2018: Journal of Pediatric Nursing
Clément Belletier, Valérie Camos
Recent studies suggest that social presence undermines performance in difficult tasks because the presence of others would automatically capture the attention needed to achieve these tasks. Here, we tested whether this attentional capture (caused by the experimenter presence) affects working memory. Several models suggest that maintenance in working memory relies on an attentional mechanism. Besides this mechanism, another nonattentional verbal rehearsal could also maintain verbal information. In experiment 1, we varied the presence of the experimenter while participants had to memorize letters during a short retention interval...
March 10, 2018: Annals of the New York Academy of Sciences
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