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https://www.readbyqxmd.com/read/29346499/repeatability-and-agreement-of-visual-acuity-using-the-etdrs-number-chart-landolt-c-chart-or-etdrs-alphabet-chart-in-eyes-with-or-without-sight-threatening-diseases
#1
Voraporn Chaikitmongkol, Onnisa Nanegrungsunk, Direk Patikulsila, Paisan Ruamviboonsuk, Neil M Bressler
Importance: The Early Treatment Diabetic Retinopathy Study (ETDRS) alphabet chart is not feasible for measuring best-corrected visual acuity (BCVA) for individuals who are unfamiliar with the Roman alphabet. The ETDRS Landolt C chart is an alternative, but it may not reflect true BCVA among those with confusion between left and right. The ETDRS number chart might overcome these limitations, but little is known regarding its reliability. Objective: To evaluate repeatability and agreement of BCVA using the ETDRS number chart or Landolt C chart compared with ETDRS alphabet charts in healthy and diseased eyes...
January 18, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29346241/chronic-central-serous-chorioretinopathy-early-and-late-morphological-and-functional-changes-after-verteporfin-photodynamic-therapy
#2
Pierluigi Iacono, Massimiliano Tedeschi, Barbara Boccassini, Adele Chiaravalloti, Monica Varano, Mariacristina Parravano
PURPOSE: To describe early and late morphological and functional changes in subjects receiving photodynamic therapy (PDT) for chronic central serous chorioretinopathy. METHODS: Patients with chronic central serous chorioretinopathy were prospectively enrolled and received standard PDT. At the baseline examination, each subject underwent complete ophthalmological examination, including best-corrected visual acuity (BCVA) assessment, fluorescein angiography and indocyanine green angiography, spectral domain optical coherence tomography, and microperimetry...
January 16, 2018: Retina
https://www.readbyqxmd.com/read/29344805/salivary-biomarkers-for-oral-cancer-and-pre-cancer-screening-a-review
#3
REVIEW
J Kaur, R Jacobs, Y Huang, N Salvo, C Politis
OBJECTIVE: The objective of the study was to conduct a systematic review of the literature assessing potential salivary biomarkers of oral cancer and pre-cancer and discuss emerging issues and challenges in relation to oral cancer and pre-cancer diagnostics. MATERIALS AND METHODS: Search for articles involved the Medline, PubMed, and EMBASE. Specific terms were used from January 1995 to March 2017 by three experts. RESULTS: This search collected 270 articles, of which 105 articles such as reviews, case reports, news, letter to editor, etc...
January 17, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29344385/improving-attendance-to-genetic-counselling-services-for-gynaecological-oncology-patients
#4
Hanoon P Pokharel, Neville F Hacker, Lesley Andrews
Background: Gynaecological cancers may be the sentinel malignancy in women who carry a mutation in BRCA1 or 2, a mis-match repair gene causing Lynch Syndrome or other genes. Despite published guidelines for referral to a genetics service, a substantial number of women do not attend for the recommended genetic assessment. The study aims to determine the outcomes of systematic follow-up of patients diagnosed with ovarian or endometrial cancer from Gynaecologic-oncology multidisciplinary meetings who were deemed appropriate for genetics assessment...
2018: Gynecologic Oncology Research and Practice
https://www.readbyqxmd.com/read/29342498/patient-reminder-and-recall-interventions-to-improve-immunization-rates
#5
REVIEW
Julie C Jacobson Vann, Robert M Jacobson, Tamera Coyne-Beasley, Josephine K Asafu-Adjei, Peter G Szilagyi
BACKGROUND: Immunization rates for children and adults are rising, but coverage levels have not reached optimal goals. As a result, vaccine-preventable diseases still occur. In an era of increasing complexity of immunization schedules, rising expectations about the performance of primary care, and large demands on primary care providers, it is important to understand and promote interventions that work in primary care settings to increase immunization coverage. One common theme across immunization programs in many nations involves the challenge of implementing a population-based approach and identifying all eligible recipients, for example the children who should receive the measles vaccine...
January 18, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29340884/-i-would-like-to-discuss-it-further-with-an-expert-a-focus-group-study-of-finnish-adults-perspectives-on-genetic-secondary-findings
#6
M Vornanen, K Aktan-Collan, N Hallowell, H Konttinen, H Kääriäinen, A Haukkala
Lowered costs of genomic sequencing facilitate analyzing large segments of genetic data. Ethical debate has focused on whether and what kind of incidental or secondary findings (SFs) to report, and how to obtain valid informed consent. However, people's support needs after receiving SFs have received less attention. We explored Finnish adults' perspectives on reporting genetic SFs. In this qualitative study which included four focus group discussions (N = 23) we used four vignette letters, each reporting a genetic SF predisposing to a different disease: familial hypercholesterolemia, long QT syndrome, Lynch syndrome, and Li-Fraumeni syndrome...
January 16, 2018: Journal of Community Genetics
https://www.readbyqxmd.com/read/29340166/withdrawal-of-antihypertensive-therapy-in-people-with-dementia-feasibility-study
#7
Veronika van der Wardt, Jennifer K Burton, Simon Conroy, Tomas Welsh, Pip Logan, Jaspal Taggar, Lukasz Tanajewski, John Gladman
Background: This study explored the feasibility of a randomised controlled withdrawal trial of antihypertensive medication in normotensive people with dementia. Feasibility aspects included response, recruitment, exclusion and drop-out rates, suitability of outcome measures, acceptability of study procedures and an indicative economic evaluation for a randomised controlled trial. Methods: A cohort study attempting the withdrawal of antihypertensive drugs where appropriate and a feasibility study of home-based blood pressure monitoring, in people with dementia treated for hypertension, was undertaken...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29339977/necessity-for-retrospective-evaluation-of-past-positive-chemicals-in-in-vitro-chromosomal-aberration-tests-using-recommended-cytotoxicity-indices
#8
Hiroshi Honda, Yurika Fujita, Toshio Kasamatsu, Anne Fuchs, Rolf Fautz, Osamu Morita
We have demonstrated that retrospective evaluation of existing data of in vitro chromosomal aberration test using the new cytotoxicity indices RICC (relative increase in cell count) or RPD (relative population doubling) reduces the false-positive rate. We have constructed an algorithm to predict the likelihood that past-positive results would differ when retested accordingly. Here, we emphasize the importance of reviewing existing in vitro chromosomal aberration test results. The present Letter not only supports the rediscovery of potentially useful chemicals excluded from further development as a result of misclassification due to in vitro false-positive results, but also contributes to the development of a precise Quantitative Structure-Activity Relationship (QSAR) model by providing an appropriate training data-set...
2018: Genes and Environment: the Official Journal of the Japanese Environmental Mutagen Society
https://www.readbyqxmd.com/read/29332496/double-jeopardy-insurance-animal-harm-and-domestic-violence
#9
Tania Signal, Nik Taylor, Karena J Burke, Luke Brownlow
Although the role of companion animals within the dynamic of domestic violence (DV) is increasingly recognized, the overlap of animal harm and insurance discrimination for victims/survivors of DV has not been considered. Prompted by a case study presented in a National Link Coalition LINK-Letter, this research note examines "Pet Insurance" policies available in Australia and whether nonaccidental injury caused by an intimate partner would be covered. We discuss the implications of exclusion criteria for victims/survivors of DV, shelters providing places for animals within a DV dynamic, and, more broadly, for cross- or mandatory-reporting (of animal harm) initiatives...
June 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29329979/how-acute-stress-may-enhance-subsequent-memory-for-threat-stimuli-outside-the-focus-of-attention-dlpfc-amygdala-decoupling
#10
Yu Luo, Guillén Fernández, Erno Hermans, Susanne Vogel, Yu Zhang, Hong Li, Floris Klumpers
Stress-related disorders, e.g., anxiety and depression, are characterized by decreased top-down control for distracting information, as well as a memory bias for threatening information. However, it is unclear how acute stress biases mnemonic encoding and leads to prioritized storage of threat-related information even if outside the focus of attention. In the current study, healthy adults (N = 53, all male) were randomly assigned to stress induction using the socially evaluated cold-pressor test (SECPT) or a control condition...
January 9, 2018: NeuroImage
https://www.readbyqxmd.com/read/29329723/prolonged-grief-and-cognitive-decline-a-prospective-population-based-study-in-middle-aged-and-older-persons
#11
Heidi C Saavedra Pérez, M Arfan Ikram, Nese Direk, Henning Tiemeier
OBJECTIVE: Bereavement can result in unresolved and prolonged grief, often termed prolonged grief disorder (PGD). The impact of PGD on cognitive functioning is poorly understood. The aim of the study was to compare the cognitive decline, assessed by repeated measures of different cognition domains, between persons with normal and PGD and a non-grieving reference population in a 7-year follow-up study. METHODS: The study sample comprised 3126 non-demented persons, mean age: 64 years, of the Rotterdam Study...
December 12, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29328239/te-polarized-design-for-metallic-slit-lenses-a-way-to-deep-subwavelength-focusing-over-a-broad-wavelength-range
#12
Yechuan Zhu, Weizheng Yuan, Wenli Li, Hao Sun, Kunlun Qi, Yiting Yu
Slit arrays based on noble metals have been widely proposed as planar transverse-magnetic (TM)-lenses, illuminated by a linearly polarized light with the polarization perpendicular to slits and implementing the focusing capability beyond the diffraction limit. However, due to intrinsic plasmonic losses, these TM-lenses cannot work efficiently in the ultraviolet wavelengths. In this Letter, taking advantage of the unique transmission through metallic slits not involving plasmonic losses, a metallic slit array with transverse-electric (TE)-polarized design is proposed, showing for the first time, to the best of our knowledge, the realization of sub-diffraction-limit focusing for ultraviolet light...
January 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29321634/navon-s-classical-paradigm-concerning-local-and-global-processing-relates-systematically-to-visual-object-classification-performance
#13
Christian Gerlach, Nicolas Poirel
Forty years ago David Navon tried to tackle a central problem in psychology concerning the time course of perceptual processing: Do we first see the details (local level) followed by the overall outlay (global level) or is it rather the other way around? He did this by developing a now classical paradigm involving the presentation of compound stimuli; large letters composed of smaller letters. Despite the usefulness of this paradigm it remains uncertain whether effects found with compound stimuli relate directly to visual object recognition...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29321126/toward-mhealth-brief-contact-interventions-in-suicide-prevention-case-series-from-the-suicide-intervention-assisted-by-messages-siam-randomized-controlled-trial
#14
Sofian Berrouiguet, Mark Erik Larsen, Catherine Mesmeur, Michel Gravey, Romain Billot, Michel Walter, Christophe Lemey, Philippe Lenca
BACKGROUND: Research indicates that maintaining contact either via letter or postcard with at-risk adults following discharge from care services after a suicide attempt (SA) can reduce reattempt risk. Pilot studies have demonstrated that interventions using mobile health (mHealth) technologies are feasible in a suicide prevention setting. OBJECTIVE: The aim of this study was to report three cases of patients recruited in the Suicide Intervention Assisted by Messages (SIAM) study to describe how a mobile intervention may influence follow-up...
January 10, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29320992/caesarean-delivery-related-blood-transfusion-correlates-in-a-tertiary-hospital-in-southwest-nigeria
#15
Fatimat M Akinlusi, Kabiru A Rabiu, Idayat A Durojaiye, Adeniyi A Adewunmi, Tawaqualit A Ottun, Yusuf A Oshodi
BACKGROUND: Caesarean delivery carries a risk of major intra-operative blood loss and its performance is often delayed by non-availability of blood and blood products. Unnecessary cross-matching and reservation of blood lead to apparent scarcity in centres with limited supply. This study set out to identify the risk factors for blood transfusion in women who underwent caesarean delivery at a tertiary obstetric unit with a view to ensuring efficient blood utilization. METHODS: A prospective cohort analysis of 906 women who had caesarean deliveries at the Lagos State University Teaching Hospital, Nigeria between January and December, 2011...
January 10, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29317844/a-survey-of-adult-referrals-to-specialist-attention-deficit-hyperactivity-disorder-clinics-in-canada
#16
Larry J Klassen, C Matthew Blackwood, Christopher J Reaume, Samuel Schaffer, James G Burns
Background: Canadian guidelines encourage family physicians to diagnose/manage adults with uncomplicated attention-deficit/hyperactivity disorder (ADHD); specialist referral is recommended only for complex cases. This retrospective case review investigated adults referred to Canadian ADHD clinics. Methods: Adult ADHD specialists reviewed referral letters/charts of patients (aged ≥18 years and no family history/known/expressed childhood ADHD) from family physicians/psychiatrists over 2 years...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29316115/multimorbidity-not-hiv-markers-predicts-unplanned-admission-among-people-with-hiv-in-regional-nsw
#17
Natalie Edmiston, Kathy Petoumenos, David J Smith
BACKGROUND: Multimorbidity and unplanned admissions are common among people with HIV (PWH). AIMS: The aim was to determine factors predictive of unplanned admission among PWH in regional NSW and compare care coordination between people with and without unplanned admissions. METHOD: A prospective cohort study of PWH attending a regional HIV service was conducted. Baseline HIV specific results and multimorbidity markers including Cumulative Illness Rating Scale (CIRS) were assessed as predictors of time to first unplanned admission using cox regression analysis...
January 8, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29313450/response-to-tennekes-2018-the-resilience-of-the-beehive-journal-of-toxicology-and-environmental-health-b-20-316-386
#18
Keith R Solomon, Gladys L Stephenson
This paper is a response to a letter from Dr. H Tennekes ("The Resilience of the Beehive" Journal of Toxicology and Environmental Health B 20: 316-386). Here we emphasize that our quantitative weight of evidence analyses were focused on the level of the honeybee colony. These colony-level responses include redundancy and resiliency as well as a number of possible sublethal effects of pesticides on the colony. We also note that the literature has shown that binding of neonicotinoid insecticides to the nicotinic acetylcholine receptor is reversible...
January 9, 2018: Journal of Toxicology and Environmental Health. Part B, Critical Reviews
https://www.readbyqxmd.com/read/29313291/parafoveal-letter-position-coding-in-reading
#19
Joshua Snell, Daisy Bertrand, Jonathan Grainger
The masked-priming lexical decision task has been the paradigm of choice for investigating how readers code for letter identity and position. Insight into the temporal integration of information between prime and target words has pointed out, among other things, that readers do not code for the absolute position of letters. This conception has spurred various accounts of the word recognition process, but the results at present do not favor one account in particular. Thus, employing a new strategy, the present study moves out of the arena of temporal- and into the arena of spatial information integration...
January 8, 2018: Memory & Cognition
https://www.readbyqxmd.com/read/29309089/evaluating-the-effectiveness-of-one-on-one-conversations-to-increase-colorectal-cancer-screening-in-a-community-based-clinical-setting
#20
Tyler J Fleming, Martha G Benitez, Miranda L Ritterman Weintraub
Context: The American Cancer Society's 80% by 2018 initiative aims to increase at-home colorectal cancer (CRC) screening. Objective: To assess the effectiveness of one-on-one conversations with patients about CRC screening on compliance with at-home fecal immunochemical tests (FITs). Setting: Federally funded health care center serving a largely minority, urban, underserved population in Vallejo, California. Methods: Patients aged 50 to 75 years were divided into 3 main intervention arms: (1) patients who received a one-on-one in-person consultation to discuss the need for CRC screening and the screening process, as well as a FIT; (2) patients who received a telephone call to discuss the need for CRC screening and the screening process before receiving a FIT in the mail; and (3) patients who were mailed a FIT with a letter explaining the importance of completing the FIT and instructions...
January 1, 2018: Journal of the American Osteopathic Association
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